Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionprotein serine kinase activity

RAF1 KALRN TTK CDC7 CDK13 SRPK3 PRKCQ OXSR1 PRKG2

1.95e-043631119GO:0106310
GeneOntologyMolecularFunctiondinitrosyl-iron complex binding

GSTA1 GSTA3

3.03e-0451112GO:0035731
GeneOntologyMolecularFunctionprotein kinase activity

RAF1 ERBB3 KALRN TTK PXK CDC7 CDK13 SRPK3 PRKCQ OXSR1 PRKG2

5.15e-0460011111GO:0004672
GeneOntologyMolecularFunctionnucleoside-triphosphatase regulator activity

PDE6D RHOD KALRN LARS1 FAM13B RHOU TIAM2 RABEP1 EIF5 HERC2

5.31e-0450711110GO:0060589
GeneOntologyMolecularFunctionGTPase regulator activity

PDE6D RHOD KALRN LARS1 FAM13B RHOU TIAM2 RABEP1 EIF5 HERC2

5.31e-0450711110GO:0030695
GeneOntologyMolecularFunctionsteroid delta-isomerase activity

GSTA1 GSTA3

6.32e-0471112GO:0004769
DomainRab5-bind

KLC2 RABEP1 KLC1

4.03e-0661113PF09311
DomainRabaptin_Rab5-bd_dom

KLC2 RABEP1 KLC1

4.03e-0661113IPR015390
DomainRibosomal_L44e

RPL36AL RPL36A

3.50e-0521112IPR000552
DomainRibosomal_L44e

RPL36AL RPL36A

3.50e-0521112PD002841
DomainRIBOSOMAL_L44E

RPL36AL RPL36A

3.50e-0521112PS01172
DomainRibosomal_L44

RPL36AL RPL36A

3.50e-0521112PF00935
Domain-

RPL36AL RPL36A

3.50e-05211123.10.450.80
DomainZF_TRAF

TRAF3 TRAF5 TRAFD1

5.59e-05131113PS50145
DomainPkinase

RAF1 KALRN TTK PXK CDC7 CDK13 SRPK3 PRKCQ OXSR1 PRKG2

9.18e-0538111110PF00069
DomainLipin_N

LPIN3 LPIN2

1.05e-0431112IPR007651
DomainLipin_mid

LPIN3 LPIN2

1.05e-0431112IPR031703
DomainKINESIN_LIGHT

KLC2 KLC1

1.05e-0431112PS01160
DomainLipin_N

LPIN3 LPIN2

1.05e-0431112PF04571
DomainADF/Cofilin

DSTN CFL1

1.05e-0431112IPR017904
DomainLipin_mid

LPIN3 LPIN2

1.05e-0431112PF16876
DomainKinesin_light_repeat

KLC2 KLC1

1.05e-0431112IPR015792
DomainSIAH-type

TRAF3 TRAF5 TRAFD1

1.08e-04161113IPR013323
DomainProt_kinase_dom

RAF1 ERBB3 KALRN TTK PXK CDC7 CDK13 SRPK3 PRKCQ OXSR1 PRKG2

1.59e-0448911111IPR000719
DomainPROTEIN_KINASE_DOM

RAF1 ERBB3 KALRN TTK PXK CDC7 CDK13 SRPK3 PRKCQ OXSR1 PRKG2

1.70e-0449311111PS50011
DomainKinesin_light

KLC2 KLC1

2.08e-0441112IPR002151
DomainSer/Thr_kinase_AS

RAF1 KALRN TTK CDC7 CDK13 SRPK3 PRKCQ OXSR1 PRKG2

2.81e-043571119IPR008271
DomainS_TKc

RAF1 KALRN TTK CDC7 CDK13 SRPK3 PRKCQ OXSR1 PRKG2

2.93e-043591119SM00220
DomainPROTEIN_KINASE_ST

RAF1 KALRN TTK CDC7 CDK13 SRPK3 PRKCQ OXSR1 PRKG2

3.11e-043621119PS00108
DomainPentatricopeptide_repeat

KLC2 PTCD2 KLC1

3.32e-04231113IPR002885
DomainGST_alpha

GSTA1 GSTA3

3.46e-0451112IPR003080
DomainTRAF-like

TRAF3 TRAF5 TRAFD1

3.78e-04241113IPR008974
DomainKinase-like_dom

RAF1 ERBB3 KALRN TTK PXK CDC7 CDK13 SRPK3 PRKCQ OXSR1 PRKG2

3.83e-0454211111IPR011009
DomainPROTEIN_KINASE_ATP

RAF1 ERBB3 KALRN TTK CDC7 CDK13 SRPK3 PRKCQ OXSR1 PRKG2

4.11e-0445911110PS00107
DomainProtein_kinase_ATP_BS

RAF1 KALRN TTK CDC7 CDK13 SRPK3 PRKCQ OXSR1 PRKG2

4.34e-043791119IPR017441
DomainLNS2

LPIN3 LPIN2

5.17e-0461112IPR013209
DomainLNS2

LPIN3 LPIN2

5.17e-0461112SM00775
DomainTNF_rcpt--assoc_TRAF

TRAF3 TRAF5

5.17e-0461112IPR012227
DomainLNS2

LPIN3 LPIN2

5.17e-0461112PF08235
DomainLNS2/PITP

LPIN3 LPIN2

5.17e-0461112IPR031315
DomainTPR_10

KLC2 KLC1

5.17e-0461112PF13374
DomainCullin_CS

CUL4B CUL1

7.21e-0471112IPR016157
DomainCULLIN

CUL4B CUL1

7.21e-0471112SM00182
DomainRBD

RAF1 TIAM2

7.21e-0471112SM00455
DomainRBD_dom

RAF1 TIAM2

7.21e-0471112IPR003116
DomainRBD

RAF1 TIAM2

7.21e-0471112PS50898
DomainCullin_neddylation_domain

CUL4B CUL1

9.57e-0481112IPR019559
Domainzf-TRAF

TRAF3 TRAF5

9.57e-0481112PF02176
DomainCullin_Nedd8

CUL4B CUL1

9.57e-0481112PF10557
DomainCullin_Nedd8

CUL4B CUL1

9.57e-0481112SM00884
DomainTPR

KLC2 PPID TTC7B CABIN1 KLC1

1.04e-031291115SM00028
DomainTPR_repeat

KLC2 PPID TTC7B CABIN1 KLC1

1.19e-031331115IPR019734
DomainCullin_homology

CUL4B CUL1

1.23e-0391112IPR016158
DomainRibosomal_zn-bd

RPL36AL RPL36A

1.23e-0391112IPR011332
Domain-

KLC2 TTK PPID TTC7B CABIN1 KLC1

1.49e-0320711161.25.40.10
DomainADF

DSTN CFL1

1.53e-03101112SM00102
DomainCofilin_ADF

DSTN CFL1

1.53e-03101112PF00241
DomainADF_H

DSTN CFL1

1.53e-03101112PS51263
DomainCullin

CUL4B CUL1

1.53e-03101112PF00888
DomainADF-H

DSTN CFL1

1.53e-03101112IPR002108
DomainCULLIN_2

CUL4B CUL1

1.53e-03101112PS50069
DomainCullin_N

CUL4B CUL1

1.53e-03101112IPR001373
DomainCULLIN_1

CUL4B CUL1

1.53e-03101112PS01256
DomainTPR-contain_dom

KLC2 PPID TTC7B CABIN1 KLC1

2.02e-031501115IPR013026
DomainTPR_1

KLC2 PPID TTC7B KLC1

2.04e-03901114IPR001440
DomainTPR_1

KLC2 PPID TTC7B KLC1

2.04e-03901114PF00515
DomainCullin_repeat-like_dom

CUL4B CUL1

2.22e-03121112IPR016159
DomainMATH

TRAF3 TRAF5

2.22e-03121112PS50144
DomainZnf_TRAF

TRAF3 TRAF5

2.22e-03121112IPR001293
DomainMATH/TRAF_dom

TRAF3 TRAF5

2.22e-03121112IPR002083
DomainMATH

TRAF3 TRAF5

2.22e-03121112SM00061
DomainMATH

TRAF3 TRAF5

2.22e-03121112PF00917
DomainTPR-like_helical_dom

KLC2 TTK PPID TTC7B CABIN1 KLC1

2.69e-032331116IPR011990
Domain-

TRAF3 TRAF5

3.04e-031411123.90.890.10
Domain-

TRAF3 TRAF5

3.04e-031411122.60.210.10
DomainTPR_REGION

KLC2 PPID TTC7B CABIN1 KLC1

3.06e-031651115PS50293
DomainTPR

KLC2 PPID TTC7B CABIN1 KLC1

3.06e-031651115PS50005
DomainCyclophilin-type_PPIase_CS

PPIB PPID

5.60e-03191112IPR020892
Pubmed

Paralog knockout profiling identifies DUSP4 and DUSP6 as a digenic dependence in MAPK pathway-driven cancers.

CUL4B CUL1 RAF1 ERBB3 TRAF3 RPL36AL DSTN RPL36A CFL1 MTMR8 PPIB GALNT13 PIAS4 CDK13 PRKCQ OXSR1

2.02e-097301131634857952
Pubmed

A high-throughput approach for measuring temporal changes in the interactome.

CUL4B CUL1 RAN GLRX3 CFL1 LARS1 KLC2 RPS17 MCM6 IDE HNRNPUL1 POLA2 PPIB PPID DIMT1 RABEP1 EIF5 NCOA7 OXSR1 CDC73 KLC1

8.65e-0914551132122863883
Pubmed

TBK1 phosphorylation activates LIR-dependent degradation of the inflammation repressor TNIP1.

CUL1 RAN RPL36AL RPL36A DSP CFL1 WDR46 LARS1 RPS17 MCM6 APOB HNRNPUL1 PPIB DIMT1 CEBPZ CDK13 C3

1.22e-089491131736574265
Pubmed

The Nse5/6-like SIMC1-SLF2 complex localizes SMC5/6 to viral replication centers.

CUL4B RAN RBM11 SETX DSP CFL1 RSF1 RPS17 HNRNPUL1 NDUFA8 PPIB CEBPZ PRRC2C EIF5 ANKRD11 CDC73 SPEN

1.31e-089541131736373674
Pubmed

Characterizing ZC3H18, a Multi-domain Protein at the Interface of RNA Production and Destruction Decisions.

RAN RBM11 RPL36AL RPL36A DSP CFL1 LARS1 RPS17 HNRNPUL1 PPIB DIMT1 CEBPZ PRRC2C CDC73 SPEN

1.61e-087311131529298432
Pubmed

Two-Dimensional Fractionation Method for Proteome-Wide Cross-Linking Mass Spectrometry Analysis.

CUL4B CUL1 RAN RPL36AL RPL36A DSP CFL1 LARS1 RPS17 MCM6 IDE SUCLG2 PPIB PRRC2C TNFSF13B EIF5

1.64e-088471131635235311
Pubmed

Genetic and Proteomic Interrogation of Lower Confidence Candidate Genes Reveals Signaling Networks in β-Catenin-Active Cancers.

CUL1 RAF1 RAN RPL36AL DSTN CFL1 LARS1 KLC2 RPS17 MCM6 HNRNPUL1 PPID CRYL1 DIMT1 ZNF608 CEBPZ OXSR1 PATJ KLC1

2.07e-0812471131927684187
Pubmed

Gain of Additional BIRC3 Protein Functions through 3'-UTR-Mediated Protein Complex Formation.

CUL1 RAN RPL36A DSP CFL1 WDR46 LARS1 RPS17 MCM6 APOB FASTKD2 IDE HNRNPUL1 PPIB DIMT1 CEBPZ KCTD16 EIF5 CDC73 SPEN

3.26e-0814251132030948266
Pubmed

Tumor suppressor BAP1 nuclear import is governed by transportin-1.

RAF1 RAN DSTN RPL36A DSP GLRX3 CFL1 TCP11L1 LARS1 RPS17 MCM6 HNRNPUL1 PPIB DIMT1 PRRC2C EIF5 PATJ KLC1

3.36e-0811491131835446349
Pubmed

Systematically defining selective autophagy receptor-specific cargo using autophagosome content profiling.

RAN TRAF3 SETX DSP CFL1 LARS1 RPS17 APOB FASTKD2 HNRNPUL1 POLA2 ANKZF1 TTK PPID GLG1 PRRC2C EIF5 C3 OXSR1

3.86e-0812971131933545068
Pubmed

Proteomic profiling of VCP substrates links VCP to K6-linked ubiquitylation and c-Myc function.

CUL1 RAN SETX DSTN DSP CFL1 RSF1 WDR46 LARS1 RPS17 MCM6 FASTKD2 HNRNPUL1 SUCLG2 PPIB DIMT1 CEBPZ LTN1 HERC2

7.47e-0813531131929467282
Pubmed

A probability-based approach for high-throughput protein phosphorylation analysis and site localization.

SETX KALRN CFL1 RSF1 KLC2 MCM6 POLA2 ANKZF1 TRAFD1 CDK13 SPEN KLC1

9.69e-085031131216964243
Pubmed

A central chaperone-like role for 14-3-3 proteins in human cells.

RAF1 SETX DSP KLC2 HNRNPUL1 TTK LPIN3 PRRC2C RABEP1 EIF5 ANKRD11 NCOA7 SRPK3 PATJ KLC1

1.36e-078611131536931259
Pubmed

SERBP1 Promotes Stress Granule Clearance by Regulating 26S Proteasome Activity and G3BP1 Ubiquitination and Protects Male Germ Cells from Thermostimuli Damage.

CUL4B RAN RPL36AL DSTN RPL36A DSP GLRX3 CFL1 LARS1 MCM6 SUCLG2 HMCES CDK13 EIF5 OXSR1

1.74e-078781131537223481
Pubmed

A protein-interaction network of interferon-stimulated genes extends the innate immune system landscape.

CUL1 RAF1 RAN TRAF3 DSTN RPL36A GLRX3 LARS1 HNRNPUL1 SUCLG2 SORT1 TRAFD1 DIMT1 CEBPZ PRRC2C TNFSF13B LTN1 OASL CABIN1

1.95e-0714401131930833792
Pubmed

The mRNA-bound proteome and its global occupancy profile on protein-coding transcripts.

RAN RPL36A WDR46 RPS17 FASTKD2 HNRNPUL1 PPIB DIMT1 CEBPZ CDK13 PRRC2C EIF5 PTCD2 SPEN

3.86e-078071131422681889
Pubmed

Genome-wide CRISPR screens identify novel regulators of wild-type and mutant p53 stability.

CUL1 RBM11 SETX DSP KLC2 TTK CDC7 PIAS4 PRRC2C RABEP1 PATJ SPEN

5.11e-075881131238580884
Pubmed

Spatiotemporal profile of postsynaptic interactomes integrates components of complex brain disorders.

CACNA1A RAN TRAF3 DSTN KALRN CFL1 PPIB JAKMIP2 PRRC2C RABEP1 KCTD16 CDC73 HERC2 CABIN1 KLC1

5.60e-079631131528671696
Pubmed

C9orf72 protein quality control by UBR5-mediated heterotypic ubiquitin chains.

CUL1 RAF1 RAN RPL36AL DSTN RPL36A DSP CFL1 LARS1 RPS17 MCM6 HNRNPUL1 NDUFA8 CDC7 TRAFD1 DIMT1 WDR48

6.60e-0712571131737317656
Pubmed

Assembly of the U5 snRNP component PRPF8 is controlled by the HSP90/R2TP chaperones.

RAN DSTN DSP GLRX3 CFL1 LARS1 RPS17 MCM6 HNRNPUL1 NDUFA8 ANKZF1 PPIB DIMT1 CEBPZ CDK13 GLG1 PRRC2C CDC73

7.22e-0714151131828515276
Pubmed

An important role for CDK2 in G1 to S checkpoint activation and DNA damage response in human embryonic stem cells.

CUL4B RAN DSTN DSP CFL1 LARS1 RPS17 MCM6 PPIB GLG1

7.33e-073971131021319273
Pubmed

Large-scale mapping of human protein-protein interactions by mass spectrometry.

CUL1 RAF1 DSTN RPL36A DSP GLRX3 CFL1 LARS1 KLC2 HNRNPUL1 PPIB SORT1 PHYH RABEP1 OXSR1 HERC2 KLC1

8.83e-0712841131717353931
Pubmed

An organelle-specific protein landscape identifies novel diseases and molecular mechanisms.

CUL4B RAF1 PDE6D GLRX3 TCP11L1 LARS1 MCM6 HNRNPUL1 PPID CDC7 LPIN3 TRAFD1 RABEP1 C3 PRKG2 KLC1 WDR48

1.30e-0613211131727173435
Pubmed

Genome-wide association analysis of metabolic traits in a birth cohort from a founder population.

APOB AR SORT1 LIPC

1.49e-0626113419060910
Pubmed

Proteome-wide identification of HSP70/HSC70 chaperone clients in human cells.

RAN RBM11 RPL36AL DSTN RPL36A DSP CFL1 MCM6 IDE HNRNPUL1 NDUFA8 SUCLG2 PPIB PPID GLG1 EIF5 OXSR1

2.07e-0613671131732687490
Pubmed

Loss of ER retention motif of AGR2 can impact mTORC signaling and promote cancer metastasis.

CUL1 RAN RPL36AL DSTN DSP GLRX3 CFL1 LARS1 HNRNPUL1 PPIB GLG1 MOV10L1 RBM46

2.34e-068071131330575818
Pubmed

A quantitative chaperone interaction network reveals the architecture of cellular protein homeostasis pathways.

CUL4B RAF1 RPS17 MCM6 PPID SORT1 CDK13 RABEP1 LTN1

3.06e-06363113925036637
Pubmed

Targeting USP10 induces degradation of oncogenic ANLN in esophageal squamous cell carcinoma.

RAN DSTN DSP CFL1 LARS1 RPS17 HNRNPUL1 PPIB DIMT1 CEBPZ PRRC2C OASL EIF5 C3 PATJ SPEN

3.17e-0612571131636526897
Pubmed

KAP1 facilitates reinstatement of heterochromatin after DNA replication.

WDR46 LARS1 RPS17 MCM6 SUCLG2 DIMT1 CEBPZ LTN1 EIF5 OXSR1 CDC73 KLC1

3.31e-067041131229955894
Pubmed

A Human Tyrosine Phosphatase Interactome Mapped by Proteomic Profiling.

RAF1 RAN TRAF3 MTMR8 RPS17 MCM6 IDE DIMT1 WDR97 LTN1 TMEM131L C3 OXSR1 CDC73

3.49e-069741131428675297
Pubmed

Hdac4 Interactions in Huntington's Disease Viewed Through the Prism of Multiomics.

CACNA1A RAN KALRN DSP PPIB TTC7B PRRC2C EIF5 C3 HERC2

3.64e-064751131031040226
Pubmed

CLEC16A interacts with retromer and TRIM27, and its loss impairs endosomal trafficking and neurodevelopment.

CUL4B RAF1 MCM6 FASTKD2 TTK CDC7 SORT1 TRAFD1 PRRC2C CDC73 HERC2

4.80e-066061131136538041
Pubmed

BAP1 regulation of the key adaptor protein NCoR1 is critical for γ-globin gene repression.

RAN RPL36AL RPL36A CFL1 WDR46 LARS1 MCM6 FASTKD2 HNRNPUL1 SUCLG2 PPIB TTK DIMT1 CEBPZ PRKCQ OXSR1

5.77e-0613181131630463901
Pubmed

Functional proteomics establishes the interaction of SIRT7 with chromatin remodeling complexes and expands its role in regulation of RNA polymerase I transcription.

CUL4B DSP RSF1 WDR46 MCM6 HNRNPUL1 CEBPZ PRRC2C OASL HERC2 SPEN

9.68e-066531131122586326
Pubmed

A Global Analysis of the Receptor Tyrosine Kinase-Protein Phosphatase Interactome.

ERBB3 SETX MTMR8 APOB PPIB TRAFD1 CDK13 HERC2 SPEN

9.90e-06420113928065597
Pubmed

SMYD3 Impedes Small Cell Lung Cancer Sensitivity to Alkylation Damage through RNF113A Methylation-Phosphorylation Cross-talk.

CUL1 RPL36AL DSTN RPL36A DSP CFL1 LARS1 RPS17 HNRNPUL1 CDK13 PRRC2C

9.96e-066551131135819319
Pubmed

Determining the differences in actin binding by human ADF and cofilin.

DSTN CFL1

1.05e-052113211812157
Pubmed

Up-regulation and pre-activation of TRAF3 and TRAF5 in inflammatory bowel disease.

TRAF3 TRAF5

1.05e-052113223329887
Pubmed

Hepatic sortilin regulates both apolipoprotein B secretion and LDL catabolism.

APOB SORT1

1.05e-052113222751103
Pubmed

Single amino acid substitutions confer the antiviral activity of the TRAF3 adaptor protein onto TRAF5.

TRAF3 TRAF5

1.05e-052113223150880
Pubmed

Crystal structures of the tetratricopeptide repeat domains of kinesin light chains: insight into cargo recognition mechanisms.

KLC2 KLC1

1.05e-052113222470497
Pubmed

Proteomic profiling identifies an UV-induced activation of cofilin-1 and destrin in human epidermis.

DSTN CFL1

1.05e-052113215816841
Pubmed

The linkage of Kennedy's neuron disease to ARA24, the first identified androgen receptor polyglutamine region-associated coactivator.

RAN AR

1.05e-052113210400640
Pubmed

ADF and Cofilin1 Control Actin Stress Fibers, Nuclear Integrity, and Cell Survival.

DSTN CFL1

1.05e-052113226655907
Pubmed

Androgen receptor transcriptional activity is required for heregulin-1β-mediated nuclear localization of the HER3/ErbB3 receptor tyrosine kinase.

ERBB3 AR

1.05e-052113237380074
Pubmed

Structural plasticity of the N-terminal capping helix of the TPR domain of kinesin light chain.

KLC2 KLC1

1.05e-052113229036226
Pubmed

ARA24/Ran enhances the androgen-dependent NH2- and COOH-terminal interaction of the androgen receptor.

RAN AR

1.05e-052113218565325
Pubmed

Contribution of ApoB-100/SORT1-Mediated Immune Microenvironment in Regulating Oxidative Stress, Inflammation, and Ferroptosis After Spinal Cord Injury.

APOB SORT1

1.05e-052113238337131
Pubmed

ADF and cofilin-1 collaborate to promote cortical actin flow and the leader bleb-based migration of confined cells.

DSTN CFL1

1.05e-052113234169836
Pubmed

N-cofilin can compensate for the loss of ADF in excitatory synapses.

DSTN CFL1

1.05e-052113222046357
Pubmed

Influence of the -514C/T polymorphism in the promoter of the hepatic lipase gene on postprandial lipoprotein metabolism.

APOB LIPC

1.05e-052113215135253
Pubmed

Association of APOB and LIPC polymorphisms with type 2 diabetes in Chinese Han population.

APOB LIPC

1.05e-052113229883758
Pubmed

Interaction between ApoB and hepatic lipase mediates the uptake of ApoB-containing lipoproteins.

APOB LIPC

1.05e-05211329685400
Pubmed

Mapping the ADF/cofilin binding site on monomeric actin by competitive cross-linking and peptide array: evidence for a second binding site on monomeric actin.

DSTN CFL1

1.05e-052113217196218
Pubmed

Solution structure of human cofilin: actin binding, pH sensitivity, and relationship to actin-depolymerizing factor.

DSTN CFL1

1.05e-052113214627701
Pubmed

Differential involvement of destrin and cofilin-1 in the control of invasive properties of Isreco1 human colon cancer cells.

DSTN CFL1

1.05e-052113217583572
Pubmed

RioK1, a new interactor of protein arginine methyltransferase 5 (PRMT5), competes with pICln for binding and modulates PRMT5 complex composition and substrate specificity.

RPL36AL RPL36A LARS1 RPS17 MCM6 HNRNPUL1 SUCLG2 DIMT1 CDC73

1.09e-05425113921081503
Pubmed

N-Terminal Acetyltransferase Naa40p Whereabouts Put into N-Terminal Proteoform Perspective.

RAN RBM11 RPL36A DSP CFL1 RSF1 LARS1 HNRNPUL1 PRRC2C RABEP1 EIF5 NCOA7 KLC1

1.12e-059341131333916271
Pubmed

A genome-wide IR-induced RAD51 foci RNAi screen identifies CDC73 involved in chromatin remodeling for DNA repair.

CUL1 RAN DSP CFL1 RPS17 CDC73

1.13e-05153113627462432
Pubmed

Study of FOXO1-interacting proteins using TurboID-based proximity labeling technology.

RAN RPL36A DSP CFL1 APOB PPIB C3

1.53e-05243113736964488
Pubmed

In-Depth In Vivo Crosslinking in Minutes by a Compact, Membrane-Permeable, and Alkynyl-Enrichable Crosslinker.

RAN RPL36AL RPL36A DSP PPRC1 CFL1 RSF1 SANBR RPS17 APOB PPIB ZNF608 CEBPZ CDK13 PRRC2C SPEN

1.76e-0514421131635575683
Pubmed

Global landscape of HIV-human protein complexes.

CUL1 DSP LARS1 MCM6 SUCLG2 ANKZF1 GLG1 CTNNA3 HERC2

1.93e-05457113922190034
Pubmed

SARS-CoV-2 nucleocapsid protein binds host mRNAs and attenuates stress granules to impair host stress response.

RAN DSP CFL1 LARS1 RPS17 MCM6 HNRNPUL1 NDUFA8 CDC73

2.14e-05463113934901782
Pubmed

The HIV-1 Tat protein recruits a ubiquitin ligase to reorganize the 7SK snRNP for transcriptional activation.

RAN RPL36AL DSTN RPL36A DSP CFL1 LARS1 RPS17 HNRNPUL1 PPIB LPIN3 DIMT1 CDK13 CDC73

2.32e-0511531131429845934
Pubmed

Synthetic Lethal and Resistance Interactions with BET Bromodomain Inhibitors in Triple-Negative Breast Cancer.

CUL4B CUL1 RAN DSTN GLRX3 RSF1 MCM6 XPA POLA2 PPID CDK13 OXSR1 CDC73

2.65e-0510141131332416067
Pubmed

Large-scale proteomics and phosphoproteomics of urinary exosomes.

CUL4B RAN DSTN KALRN DSP PPIB TIAM2 GSTA1 CRYL1 GLG1 OXSR1 PATJ SPEN

2.71e-0510161131319056867
Pubmed

The RNA-mediated estrogen receptor α interactome of hormone-dependent human breast cancer cell nuclei.

RPL36AL SETX RHOD RPS17 NDUFA8 ANKZF1 DIMT1 CEBPZ CDK13 GLG1 LTN1 EIF5 ANKRD11 HERC2 PATJ SPEN

2.77e-0514971131631527615
Pubmed

Cell cycle-dependent phosphorylation regulates RECQL4 pathway choice and ubiquitination in DNA double-strand break repair.

CUL4B CUL1 RAN RPL36A GLRX3 CFL1 PEG3 LARS1 RPS17 MCM6 FASTKD2 HNRNPUL1 TTK DIMT1 PRRC2C

2.85e-0513351131529229926
Pubmed

The midnolin-proteasome pathway catches proteins for ubiquitination-independent degradation.

RAN RPL36AL RPL36A DSP CFL1 RPS17 NDUFA8 PPIB SORT1 DIMT1

2.90e-056041131037616343
Pubmed

The ubiquitin-specific protease USP36 SUMOylates EXOSC10 and promotes the nucleolar RNA exosome function in rRNA processing.

RPL36AL RPL36A WDR46 RPS17 DIMT1 CEBPZ CDK13 PRRC2C C3

2.97e-05483113936912080
Pubmed

Genetic differences between the determinants of lipid profile phenotypes in African and European Americans: the Jackson Heart Study.

APOB SORT1 LIPC

3.12e-0519113319148283
Pubmed

Synapsin and synaptic vesicle protein expression during embryonic and post-natal lens fiber cell differentiation.

KLC2 RABEP1 KLC1

3.12e-0519113315529118
Pubmed

Adipose tissue deficiency, glucose intolerance, and increased atherosclerosis result from mutation in the mouse fatty liver dystrophy (fld) gene.

LPIN3 LPIN2

3.13e-053113210884287
Pubmed

Temporal and spatial regulation of the phosphatidate phosphatases lipin 1 and 2.

LPIN3 LPIN2

3.13e-053113218694939
Pubmed

Identification of lipidomic profiles associated with drug-resistant prostate cancer cells.

LPIN3 LPIN2

3.13e-053113233596934
Pubmed

Actin-Depolymerizing Factor and Cofilin-1 Have Unique and Overlapping Functions in Regulating Intestinal Epithelial Junctions and Mucosal Inflammation.

DSTN CFL1

3.13e-053113226878213
Pubmed

Actin filament turnover drives leading edge growth during myelin sheath formation in the central nervous system.

DSTN CFL1

3.13e-053113226166299
Pubmed

Signal transduction elements of TC21, an oncogenic member of the R-Ras subfamily of GTP-binding proteins.

RAF1 TRAF3

3.13e-053113210557073
Pubmed

Actin-depolymerizing factor and cofilin-1 play overlapping roles in promoting rapid F-actin depolymerization in mammalian nonmuscle cells.

DSTN CFL1

3.13e-053113215548599
Pubmed

Effect of SORT1, APOB and APOE polymorphisms on LDL-C and coronary heart disease in Pakistani subjects and their comparison with Northwick Park Heart Study II.

APOB SORT1

3.13e-053113227112212
Pubmed

Structural mechanism of nuclear transport mediated by importin β and flexible amphiphilic proteins.

CUL4B CUL1

3.13e-053113225435324
Pubmed

The bridging function of hepatic lipase clears plasma cholesterol in LDL receptor-deficient "apoB-48-only" and "apoB-100-only" mice.

APOB LIPC

3.13e-053113214679168
Pubmed

Complete loss of function of the ubiquitin ligase HERC2 causes a severe neurodevelopmental phenotype.

XPA HERC2

3.13e-053113227759030
Pubmed

A high-carbohydrate diet effects on the A allele of hepatic lipase polymorphism on the apoB100/apoAI ratio in young Chinese males.

APOB LIPC

3.13e-053113223457133
Pubmed

The three mouse actin-depolymerizing factor/cofilins evolved to fulfill cell-type-specific requirements for actin dynamics.

DSTN CFL1

3.13e-053113211809832
Pubmed

Characterisation of an mRNA encoding a human ribosomal protein homologous to the yeast L44 ribosomal protein.

RPL36AL RPL36A

3.13e-05311323542712
Pubmed

Androgen and glucocorticoid receptors interact with insulin degrading enzyme.

IDE AR

3.13e-05311328051160
Pubmed

Attention-Deficit/Hyperactivity Disorder-like Phenotype in a Mouse Model with Impaired Actin Dynamics.

DSTN CFL1

3.13e-053113224768258
Pubmed

Specificity and heregulin regulation of Ebp1 (ErbB3 binding protein 1) mediated repression of androgen receptor signalling.

ERBB3 AR

3.13e-053113215583694
Pubmed

HepaCAM inhibits cell proliferation and invasion in prostate cancer by suppressing nuclear translocation of the androgen receptor via its cytoplasmic domain.

RAN AR

3.13e-053113230664187
Pubmed

ADF/n-cofilin-dependent actin turnover determines platelet formation and sizing.

DSTN CFL1

3.13e-053113220530287
Pubmed

Lipin 2/3 phosphatidic acid phosphatases maintain phospholipid homeostasis to regulate chylomicron synthesis.

LPIN3 LPIN2

3.13e-053113230507612
Pubmed

Lipin proteins form homo- and hetero-oligomers.

LPIN3 LPIN2

3.13e-053113220735359
Pubmed

Study of LPIN1, LPIN2 and LPIN3 in rhabdomyolysis and exercise-induced myalgia.

LPIN3 LPIN2

3.13e-053113222481384
Pubmed

Cyclophilin D, a component of the permeability transition-pore, is an apoptosis repressor.

PPIB PPID

3.13e-053113214729611
Pubmed

Coordinated regulation of XPA stability by ATR and HERC2 during nucleotide excision repair.

XPA HERC2

3.13e-053113223178497
Pubmed

TIRF microscopy analysis of human Cof1, Cof2, and ADF effects on actin filament severing and turnover.

DSTN CFL1

3.13e-053113226996939
Pubmed

ADF/cofilin regulates secretory cargo sorting at the TGN via the Ca2+ ATPase SPCA1.

DSTN CFL1

3.13e-053113221571222
Pubmed

Lipin-1 and lipin-3 together determine adiposity in vivo.

LPIN3 LPIN2

3.13e-053113224634820
Pubmed

A study of the expression and interaction of Destrin, cofilin, and LIMK in Debakey I type thoracic aortic dissection tissue.

DSTN CFL1

3.13e-053113220873970
InteractionH1-4 interactions

RAN TRAF3 RPL36AL PPRC1 RSF1 RPS17 HNRNPUL1 POLA2 LPIN3 TRAFD1 DIMT1 CEBPZ CDK13 OASL FER1L5

3.93e-0665611315int:H1-4
InteractionCAPZB interactions

CUL4B RPL36AL RPL36A RHOD CFL1 RSF1 LARS1 RPS17 IDE NDUFA8 AR CDC7 PRRC2C RABEP1 EIF5 CDC73 PATJ CABIN1 KLC1

5.60e-06104911319int:CAPZB
InteractionCDK2 interactions

CUL4B CUL1 RAN DSTN DSP CFL1 LARS1 RPS17 MCM6 POLA2 PPIB TTK CDC7 SORT1 CDK13 GLG1

7.60e-0678311316int:CDK2
InteractionBIRC3 interactions

RAF1 RAN TRAF3 RPL36A DSP CFL1 WDR46 LARS1 RPS17 MCM6 APOB FASTKD2 IDE HNRNPUL1 PPIB DIMT1 CEBPZ KCTD16 EIF5 CDC73 SPEN

1.46e-05133411321int:BIRC3
InteractionEED interactions

CUL4B CUL1 RAN RBM11 SETX DSTN DSP GLRX3 CFL1 PEG3 WDR46 LARS1 MCM6 HNRNPUL1 NDUFA8 PPIB AR DIMT1 CEBPZ LTN1 HERC2 SPEN

1.49e-05144511322int:EED
InteractionCOP1 interactions

CUL4B CUL1 RBM11 SETX DSP TTK LPIN3 ZNF608 LPIN2 PTCD2

1.52e-0532611310int:COP1
InteractionFOXO1 interactions

RAN TRAF3 RPL36A DSP CFL1 APOB PPIB FAM13B AR C3

2.60e-0534711310int:FOXO1
InteractionMYCBP2 interactions

CUL4B RAF1 RAN ERBB3 CFL1 AR PRRC2C CTNNA3 HERC2 WDR48

3.15e-0535511310int:MYCBP2
InteractionBAP1 interactions

CUL4B RAF1 RAN DSTN RPL36A DSP GLRX3 CFL1 TCP11L1 LARS1 RPS17 MCM6 HNRNPUL1 PPIB AR DIMT1 PRRC2C EIF5 PATJ KLC1

3.89e-05131411320int:BAP1
InteractionSMC5 interactions

CUL4B RAN RBM11 SETX DSP CFL1 RSF1 RPS17 HNRNPUL1 NDUFA8 PPIB CEBPZ PRRC2C EIF5 ANKRD11 CDC73 SPEN

4.12e-05100011317int:SMC5
InteractionTNIP1 interactions

CUL1 RAN TRAF3 RPL36AL RPL36A DSP CFL1 WDR46 LARS1 RPS17 MCM6 APOB HNRNPUL1 PPIB DIMT1 CEBPZ CDK13 GLG1 C3

4.44e-05121711319int:TNIP1
InteractionGAR1 interactions

CUL4B RAF1 RPL36AL WDR46 GSTA1 CEBPZ SRPK3 HERC2

4.95e-052321138int:GAR1
InteractionH2AC8 interactions

CUL4B CUL1 RPL36AL RSF1 RPS17 MCM6 HMCES

6.32e-051771137int:H2AC8
InteractionTUBB interactions

CUL4B CUL1 RAF1 ERBB3 SETX RPL36A TCP11L1 LARS1 TTK PPID SORT1 CDK13 LTN1 EIF5

6.33e-0573511314int:TUBB
InteractionUCHL5 interactions

RAF1 DSP CFL1 KLC2 APOB IDE AR HERC2 KLC1

7.87e-053191139int:UCHL5
InteractionEEF1A1 interactions

CUL4B CUL1 RAF1 RAN DSP CFL1 LARS1 RPS17 HNRNPUL1 PPID LIPC PRRC2C CDC73 HERC2

9.29e-0576211314int:EEF1A1
InteractionNAA40 interactions

RAF1 RAN RBM11 RPL36A DSP GLRX3 CFL1 RSF1 LARS1 KLC2 HNRNPUL1 PRRC2C RABEP1 EIF5 NCOA7 KLC1

1.11e-0497811316int:NAA40
InteractionZC3H18 interactions

RAN RBM11 RPL36AL RPL36A DSP CFL1 LARS1 RPS17 HNRNPUL1 PPIB DIMT1 CEBPZ PRRC2C CDC73 SPEN

1.14e-0487711315int:ZC3H18
InteractionEEF2 interactions

CUL4B CUL1 RAF1 RAN DSP LARS1 RPS17 NDUFA8 AR CEBPZ CDK13 CDC73

1.15e-0458811312int:EEF2
InteractionXPA interactions

XPA HMCES RHOU CDC7 HERC2

1.23e-04861135int:XPA
InteractionCSTA interactions

CUL4B RAF1 DSP OASL HERC2 CABIN1

1.23e-041371136int:CSTA
InteractionGAPDH interactions

CUL4B CUL1 RAF1 RAN DSTN DSP CFL1 PPIB AR LIPC PRRC2C CDC73 HERC2

1.24e-0468611313int:GAPDH
InteractionSERBP1 interactions

CUL4B CUL1 RAF1 RAN RPL36AL DSTN RPL36A DSP GLRX3 CFL1 LARS1 MCM6 SUCLG2 HMCES PIAS4 DIMT1 CDK13 PRRC2C EIF5 OXSR1

1.28e-04143211320int:SERBP1
InteractionYWHAZ interactions

CUL1 RAF1 ERBB3 CFL1 RSF1 KLC2 HNRNPUL1 FAM13B AR LPIN3 RABEP1 KCTD16 EIF5 LPIN2 CTNNA3 C3 CDC73 HERC2 KLC1

1.29e-04131911319int:YWHAZ
InteractionCEBPB interactions

RAN DSP GLRX3 CFL1 RSF1 LARS1 KLC2 RPS17 MCM6 XPA HNRNPUL1 NDUFA8 POLA2 PPIB AR CDK13 PRRC2C EIF5 CDC73 KLC1

1.41e-04144311320int:CEBPB
InteractionACE2 interactions

CUL4B RAN RBM11 RPL36AL DSTN RPL36A DSP CFL1 LARS1 RPS17 MCM6 HNRNPUL1 PPIB PIAS4 PRRC2C RABEP1 NCOA7

1.42e-04110611317int:ACE2
InteractionNCBP2 interactions

CUL1 RAF1 RAN PPRC1 EIF5 SPEN

1.44e-041411136int:NCBP2
InteractionSRP9 interactions

RAF1 RHOD LARS1 RHOU TMPRSS11B DIMT1 GLG1 PRRC2C SRPK3 CDC73

1.46e-0442711310int:SRP9
InteractionNOP10 interactions

RAF1 RPL36AL SRPK3 HERC2 WDR48

1.61e-04911135int:NOP10
InteractionCNBP interactions

RAF1 RAN ERBB3 RPS17 HNRNPUL1 AR TMPRSS11B PRRC2C

1.65e-042761138int:CNBP
InteractionCAP1 interactions

RAF1 RAN TRAF3 DSP CFL1 LARS1 MCM6

1.68e-042071137int:CAP1
InteractionFAHD2A interactions

SETX DSTN CFL1 HMCES

1.77e-04501134int:FAHD2A
InteractionWDR82 interactions

CUL4B RAF1 RBM11 TRAF3 SETX DSP CDC73

2.00e-042131137int:WDR82
InteractionDCAF8 interactions

CUL4B RAF1 RAN RBM11 DSP FASTKD2

2.09e-041511136int:DCAF8
InteractionMYCN interactions

CUL4B RAN RPL36AL DSTN RPL36A DSP CFL1 RPS17 APOB FASTKD2 HNRNPUL1 NDUFA8 PPIB HMCES DIMT1 CEBPZ CDK13 PRRC2C C3

2.17e-04137311319int:MYCN
InteractionEIF6 interactions

CUL1 RAF1 RAN RBM11 CFL1 POLA2 PPIB CEBPZ LTN1

2.17e-043651139int:EIF6
InteractionCIAO1 interactions

RBM11 TRAF5 RPL36AL DSP GLRX3 LARS1 POLA2 CDC73

2.26e-042891138int:CIAO1
InteractionAGR2 interactions

CUL1 RAN RPL36AL DSTN DSP GLRX3 CFL1 LARS1 HNRNPUL1 PPIB GLG1 MOV10L1 ANKRD11 RBM46 C3

2.26e-0493411315int:AGR2
InteractionRBM28 interactions

CUL1 RAF1 RPL36AL WDR46 RPS17 SORT1 CEBPZ OASL SRPK3

2.30e-043681139int:RBM28
InteractionTRPC4AP interactions

CUL4B RBM11 DSP PRRC2C KLC1

2.87e-041031135int:TRPC4AP
InteractionSMU1 interactions

CUL4B RAF1 DSTN DSP AR RABEP1 SPEN

2.95e-042271137int:SMU1
InteractionNEFL interactions

RBM11 KALRN IDE AR PIAS4 RABEP1

2.96e-041611136int:NEFL
InteractionRSBN1 interactions

RAF1 RPL36AL PPRC1 WDR46 CEBPZ OASL

2.96e-041611136int:RSBN1
InteractionTNIK interactions

CACNA1A RAF1 DSTN KALRN GALNT13 TIAM2 CDC73 HERC2 CABIN1

2.97e-043811139int:TNIK
InteractionPCBD1 interactions

CUL4B CUL1 RAF1 CEBPZ PRRC2C

3.00e-041041135int:PCBD1
InteractionRPL35 interactions

CUL4B CUL1 RPL36AL RPL36A WDR46 RPS17 HNRNPUL1 CEBPZ OASL EIF5 HERC2

3.02e-0455811311int:RPL35
InteractionHSP90AB1 interactions

CUL4B CUL1 RAF1 ERBB3 DSP LARS1 MCM6 HNRNPUL1 PPID AR CRYL1 CDK13 PRRC2C CDC73 SPEN

3.04e-0496011315int:HSP90AB1
InteractionGSTA3 interactions

GSTA1 GSTA3

3.08e-0451132int:GSTA3
InteractionCLTC interactions

CUL1 RAF1 RHOD LARS1 KLC2 FASTKD2 AR RHOU TMPRSS11B TRAFD1 CDC73 HERC2

3.11e-0465511312int:CLTC
InteractionTNFRSF17 interactions

TRAF3 TRAF5 TNFSF13B

3.19e-04241133int:TNFRSF17
InteractionMDM2 interactions

CUL4B CUL1 ERBB3 TRAF5 RPL36AL RPL36A MCM6 APOB PPIB AR PIAS4 HERC2

3.24e-0465811312int:MDM2
GeneFamilyLipins

LPIN3 LPIN2

4.81e-0537321043
GeneFamilyTNF receptor associated factors

TRAF3 TRAF5

3.33e-0477321056
GeneFamilyCullins

CUL4B CUL1

4.43e-0487321032
GeneFamilyUPF1 like RNA helicases

SETX MOV10L1

8.64e-04117321169
GeneFamilyTetratricopeptide repeat domain containing|Bardet-Biedl syndrome associated|BBSome

KLC2 PPID TTC7B KLC1

1.21e-03115734769
GeneFamilyCyclophilin peptidylprolyl isomerases

PPIB PPID

2.63e-0319732909
GeneFamilyRho family GTPases

RHOD RHOU

2.91e-0320732390
GeneFamilyGlutathione S-transferases

GSTA1 GSTA3

4.54e-0325732567
CoexpressionGSE22611_UNSTIM_VS_2H_MDP_STIM_MUTANT_NOD2_TRANSDUCED_HEK293T_CELL_DN

CUL1 PDE6D RSF1 CRYL1 PHYH GLG1 CDC73 CABIN1

1.50e-061861138M8175
ToppCelldroplet-Marrow-nan-3m|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SETX RSF1 HNRNPUL1 ZNF608 CEBPZ PRRC2C ANKRD11

4.57e-0718411371154a5ad7b8512272b7476f949ddac350910bfb7
ToppCellPBMC_fresh-frozen-Severe-critical_progression_d03-09-Lymphocytic-Lymphocytic_T-CD8-positive,_alpha-beta_T_cell-T_CD8_c07-TYROBP|Severe-critical_progression_d03-09 / Compartment, severity and other cell annotations on 10x 3' data (130k)

CACNA1A DSTN RPL36A CFL1 LRRC69 RPS17 TNFSF13B

6.09e-0719211373b0a52e4e77ae4539a034dcb419773b8e2aa5d51
ToppCell(04)_Interm._basal>secr.-(2)_GFP_FOXI1|(04)_Interm._basal>secr. / shred by cell type by condition

SETX RSF1 PPIB PRRC2C LPIN2 ANKRD11 NCOA7

7.74e-07199113753ca3861f9e00dab3f3fbefb0837857ee39ab084
ToppCellmegakaryocytic-Megakaryocyte|megakaryocytic / Lineage and Cell class

RAN RPL36AL RPL36A CFL1 RPS17 PPIB TTK

8.01e-072001137806e745ac1556b8158719f14a757df6e6d7ac77f
ToppCellfacs-Large_Intestine-Proximal-3m-Epithelial|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ERBB3 DSP CDK13 LPIN2 NCOA7 PRKG2

5.33e-061731136e1378201b15ffb98e196ac39fe3ee4b4078953bd
ToppCellfacs-Large_Intestine-Proximal-3m|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ERBB3 DSP CDK13 LPIN2 NCOA7 PRKG2

5.33e-06173113699532bb768ee35fed939a377acb5215d3f8904bd
ToppCellTuft-tuft-4|World / Class top

TRAF5 ACTRT3 KALRN JAKMIP2 FAM13B OASL

5.51e-061741136d6f306ebf66061bf9e9742000bfedce12d277452
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell-|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

DSTN KALRN SORT1 CTNNA3 TMEM131L SRPK3

9.66e-061921136bfab13793e54de2550ee171397f7ece0625cdb4a
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

DSTN KALRN SORT1 CTNNA3 TMEM131L SRPK3

9.66e-061921136b54b0d5b88139905521c8d5d58332e89c08d589c
ToppCellMild_COVID-19|World / Disease group,lineage and cell class (2021.01.30)

KALRN TRIM34 TRAFD1 OASL LPIN2 NCOA7

9.95e-061931136325b0768827bf8701bfb7f686bb11fd8b1a41a5c
ToppCell5'-Adult-SmallIntestine-Epithelial-Tuft-related-BEST4+_epithelial|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

DSP TIAM2 CRYL1 RABEP1 PRKG2 GP2

1.06e-051951136e87b11e3242fdbed2e7f383e6876ec375af32bd4
ToppCellB_cells-ISG-high_B_cells|B_cells / Immune cells in Kidney/Urine in Lupus Nephritis

CACNA1A DSP TRAFD1 TNFSF13B OASL LPIN2

1.06e-051951136b64d9e1a8834401b4dc501566546647754ae21fc
ToppCellBAL-Mild|BAL / Location, Disease Group, Cell group, Cell class (2021.03.09)

RPL36AL KALRN TRIM34 TRAFD1 OASL NCOA7

1.09e-0519611366566e6671257f7df4d3f375e84f0b292ab4bcde1
ToppCellBAL-Mild|BAL / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

RPL36AL KALRN TRIM34 TRAFD1 OASL NCOA7

1.09e-0519611363408d561d29802fca9eff5c54ccf70818d240cea
ToppCell(00)_Basal-(2)_GFP_FOXI1|(00)_Basal / shred by cell type by condition

SETX RSF1 PPIB PRRC2C RABEP1 ANKRD11

1.18e-05199113619674e1eaeb51e4196d847cb62aa437c852951d3
ToppCellControl_saline-Epithelial_airway-airway_epithelial-Airway-Club|Control_saline / Treatment groups by lineage, cell group, cell type

TMC1 RHOD DSP JAKMIP2 GSTA3 C3

1.18e-0519911365cc8b553a58669a30eb10845beb23983dcdf5a6a
ToppCellASK440-Epithelial|ASK440 / Donor, Lineage and Cell class of Lung cells from Dropseq

ERBB3 DSTN DSP GSTA1 C3 PATJ

1.22e-052001136cb617e2a0ca82b470b473b8d5906bc8879c85718
ToppCell(13)_Th17|World / shred on Cell_type and subtype

RPL36AL RPL36A CFL1 RPS17 TNFSF13B LPIN2

1.33e-052031136e8d5db46093160d403ecd51142c3939d522bca8b
ToppCelldroplet-Liver-LIVER_NPC-30m-Epithelial-hepatocyte|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TRAF5 DSTN GSTA1 GSTA3 PHYH

2.91e-05140113539083c3e288d1878fdc4c798e600fb156daff8a9
ToppCelldroplet-Liver-LIVER_NPC-30m-Epithelial|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TRAF5 DSTN GSTA1 GSTA3 PHYH

2.91e-05140113506e14a375ea85175c809ff5a0ea16e865ccb4ad5
ToppCelldroplet-Liver-Npc-21m-Epithelial-nan|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

KLC2 FASTKD2 GSTA1 LIPC

3.22e-05711134cf4c8715c2bd77fc86e45cc01bcc7aa6044e091d
ToppCell18-Distal-Epithelial-Basal_cell|Distal / Age, Tissue, Lineage and Cell class

CACNA1A RBM11 DSP GSTA1 NCOA7

5.18e-051581135183f445967e09e871c93d8e94781ed9fec894169
ToppCellClub_cells-Donor_05|World / lung cells shred on cell class, cell subclass, sample id

DSP APOB GALNT13 GSTA1 LIPC

6.19e-0516411354e25e6362ef793b08de2f4d1dccb6b1fc9c072a5
ToppCelldroplet-Spleen-SPLEEN-1m-Myeloid-granulocyte|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DSTN RHOU TIAM2 SORT1 C3

6.37e-051651135b671c6a950e70f64776c2104baccb3dc2bb6a1ba
ToppCellPBMC-Severe-Lymphocyte-B-B_cell-B_naive-B_naive-1|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

TRAF5 DSP RPS17 ZNF608 TMEM131L

6.37e-051651135fead3f2032f8fa5f7f0159a4434989b3d65debbb
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Degenerative_Proximal_Tubule_Epithelial_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

CACNA1A TMC1 GSTA1 CTNNA3 PATJ

6.74e-0516711353edb0570e583bb527165bcd8a4c25a042054043b
ToppCellPBMC_fresh-frozen-Mild-Moderate_progression_d02_child-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD4_c01-LEF1|Mild-Moderate_progression_d02_child / Compartment, severity and other cell annotations on 10x 3' data (130k)

CUL1 ERBB3 ANKZF1 PRKCQ

6.83e-0586113479c4326df78f0a5b3ef13b2fb4e5074934536e35
ToppCell343B-Lymphocytic-NK_cells-NK_cell_E|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)

KALRN KLC2 POLA2 PATJ ZNF726

8.18e-051741135a1f745962a104c6f4b86b7e482da8755384c773a
ToppCellPND07-Immune-Immune_Myeloid-Megakaryocyte/Platelet-Megakaryocyte/Platelet-Megakaryocyte/Platelet_mature|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

TMC1 KALRN LIPC LPIN2 PRKCQ

8.18e-051741135a3f4981b10afa9d41a1c66c7f98522a8a534f82b
ToppCellPND07-Immune-Immune_Myeloid-Megakaryocyte/Platelet|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

TMC1 KALRN LIPC LPIN2 PRKCQ

8.18e-0517411356cc108dde4b3f98a78a6040280f0d5e4aaa5bd75
ToppCellPND07-Immune-Immune_Myeloid-Megakaryocyte/Platelet-Megakaryocyte/Platelet|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

TMC1 KALRN LIPC LPIN2 PRKCQ

8.18e-0517411354b8bc5568e36031c8ecf001bb646809038c23919
ToppCellfacs-Large_Intestine-Proximal-3m-Epithelial-enterocyte_of_epithelium_of_large_intestine|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RHOD APOB LPIN2 NCOA7 PRKG2

8.63e-0517611357622f5a8e7320cc7b593141854107ecaf4adff7f
ToppCellfacs-Marrow-Granulocytes-3m-Myeloid|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DSTN RHOU SORT1 TNFSF13B C3

8.87e-051771135065bebd22031f143e90a407f952b444a3f8818c7
ToppCellE16.5-Immune-Immune_Myeloid-Megakaryocyte/Platelet-Megakaryocyte/Platelet|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

TMC1 KALRN LIPC LPIN2 PRKCQ

8.87e-05177113584591e28482ab62a5ef41e61043eb64912766356
ToppCellE16.5-Immune-Immune_Myeloid-Megakaryocyte/Platelet-Megakaryocyte/Platelet-Megakaryocyte/Platelet_mature|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

TMC1 KALRN LIPC LPIN2 PRKCQ

8.87e-0517711354bc100062891d07cacd10ffba38966cc6302c92f
ToppCellE16.5-Immune-Immune_Myeloid-Megakaryocyte/Platelet|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

TMC1 KALRN LIPC LPIN2 PRKCQ

8.87e-0517711359f3a2adb9cd4f0a059afc87b6e377a9702154bb1
ToppCellfacs-Marrow-Granulocytes-3m|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DSTN RHOU SORT1 TNFSF13B C3

8.87e-051771135eb304f20aab075bd17aa3aef819386c0e1a235bd
ToppCelldroplet-Tongue-nan-24m-Epithelial|Tongue / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DSP IDE GSTA1 GSTA3 OASL

9.10e-051781135a3176b2b335db22bb0fb71aafa5d7a287809396e
ToppCellC_00|World / shred on cell type and cluster

TRAF5 RPL36AL RPS17 PRRC2C ANKRD11

9.35e-051791135da2dadc3266ffebd4a34ac61bfa05fddcadcde4c
ToppCellCiliated_cells-A-Donor_08|World / lung cells shred on cell class, cell subclass, sample id

KALRN GSTA1 GSTA3 LPIN3 ZNF662

9.35e-0517911351c41314b6fcfcac8d62034e7037570120d58f20f
ToppCelldroplet-Liver-LIVER_NPC-30m-Epithelial-nan|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DSTN TIAM2 GSTA3 PHYH

9.66e-0594113447e02e184a259a61c86c81503f36da243c5e3e8d
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD|renal_cortex_nuclei / Celltypes from Cells and Nuclei per compartment and clinical group

CACNA1A GSTA1 KCTD16 PATJ GP2

9.85e-051811135c80ffa2ded5975a88e9a1a7d333196f95237bf0a
ToppCelldroplet-Pancreas-PANCREAS-30m-Epithelial|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RPL36A RPS17 PPIB GSTA3 GP2

9.85e-051811135cf8f7798559fedf91ee21b3ebc93171cfd14f89f
ToppCelldroplet-Pancreas-PANCREAS|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RPL36A RPS17 PPIB GSTA3 GP2

1.01e-041821135ecb8c1d0b9e0766fae4dd2568456eb78a3cfce9a
ToppCelldroplet-Pancreas-PANCREAS-30m|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RPL36A RPS17 PPIB GSTA3 GP2

1.01e-041821135cf1ccfc4709364763fa73e60d5f2c05ce268d5c1
ToppCellfacs-Pancreas-Endocrine-18m-Epithelial-pancreatic_A_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RPL36A RPS17 RHOU GALNT13 KCTD16

1.01e-041821135f5f42e23832d0210560009ce6fd8eee89751e252
ToppCellRA-13._Vascular_Smooth_Muscle|RA / Chamber and Cluster_Paper

CACNA1A TRAF5 DSTN KALRN SORT1

1.04e-041831135818fd886e0188091310825f9145fa53328f2c979
ToppCelldroplet-Tongue-nan-24m-Epithelial-keratinocyte|Tongue / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DSP IDE GSTA1 OASL PSAPL1

1.04e-0418311359e6c96ada930e8559246a270dfc69fb3cbb3bdf3
ToppCellRA-13._Vascular_Smooth_Muscle|World / Chamber and Cluster_Paper

CACNA1A TRAF5 DSTN KALRN SORT1

1.04e-041831135cae2ee08f985a6f005b4b8e959e465350315156a
ToppCellControl-Epithelial_alveolar-AT_2|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

DSP GALNT13 C3 PRKCQ PATJ

1.06e-04184113551e129b3fcc2df083eda05a3afe3717218b1e52b
ToppCellControl-Epithelial_alveolar-AT_2-AT2_Progenitor|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

DSP GALNT13 C3 PRKCQ PATJ

1.09e-0418511358ca1374501eca01d8468130b74d50abfd4329fbe
ToppCellLPS-IL1RA-Epithelial_alveolar-AT_2-AT2_Progenitor|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

PPIB GALNT13 C3 PRKCQ PATJ

1.09e-041851135929b68b05b7686341329ac756d7df172cb4b810b
ToppCelldroplet-Marrow-BM-30m-Hematologic-megakaryocyte-erythroid_progenitor_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DSTN MCM6 CDC7 TNFSF13B C3

1.09e-0418511354157cc14b06bb99ee67ac1526622cf546e727efc
ToppCelldroplet-Spleen-nan-3m|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SETX RPL36A RPS17 PXK PRRC2C

1.12e-04186113526f1e9930adf2fe4af0819e56f69915bd8330e4a
ToppCelldroplet-Spleen-nan-3m-Lymphocytic|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SETX RPL36A RPS17 PXK PRRC2C

1.15e-04187113591c8e93bde0d1d1a4e324b0acf2afda00f4fb3bf
ToppCellLPS-antiTNF-Epithelial_alveolar|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

DSP GALNT13 C3 PRKCQ PATJ

1.15e-041871135201ff693e4756ee3e44762885b3a303a77eb535b
ToppCellLPS-antiTNF-Epithelial_alveolar-AT_1-Differentiating_AT2|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

DSP GALNT13 C3 PRKCQ PATJ

1.15e-04187113558d48128547ee3513d0bf7f78e61b76b1c472ca9
ToppCelldroplet-Spleen-nan-3m-Lymphocytic-nan|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SETX RPL36A RPS17 PXK PRRC2C

1.15e-041871135382db691eb0b3e089e816bed3d6699cc2d4e1bda
ToppCellLPS-IL1RA+antiTNF-Epithelial_alveolar|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

DSP GALNT13 C3 PRKCQ PATJ

1.18e-04188113543a0508d2524a5b310e89e9422843dcaab999bc3
ToppCellPCW_13-14-Epithelial-Epithelial_airway-epi_proximal_progenitor1_(6)|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung

ERBB3 DSP CTNNA3 PRKG2 PATJ

1.18e-0418811350d86044bc340e3efb90d0022dd299873639d831c
ToppCellPCW_10-12-Epithelial-Epithelial_airway-epi_proximal_progenitor1_(6)|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung

ERBB3 DSP AR CTNNA3 PATJ

1.18e-041881135beb2df2332a46cc81b10e8e29fc9829020111f03
ToppCellfacs-Lung-EPCAM-24m-Mesenchymal-fibroblast_of_lung|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GSTA3 SORT1 TNFSF13B C3 PRKG2

1.24e-04190113500fd993675faf53adf985b9316a18c8a33242029
ToppCellfacs-Lung-EPCAM-24m-Mesenchymal-Alveolar_Fibroblast|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GSTA3 SORT1 TNFSF13B C3 PRKG2

1.24e-0419011358cda09d761c6b504a744959d587c183f94f1beeb
ToppCellPBMC_fresh-frozen-Severe-critical_convalescent_d14-21|PBMC_fresh-frozen / Compartment, severity and other cell annotations on 10x 3' data (130k)

CACNA1A RPL36A LRRC69 RPS17 TNFSF13B

1.24e-0419011357179f980f895d3e5b839b5ae26b5c991787bfe3a
ToppCelldroplet-Large_Intestine-COLON_PROXIMAL|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DSP APOB HNRNPUL1 PRRC2C ANKRD11

1.27e-04191113560c986d2dcbc19d9338c03da6cb5e1d92fd48f8e
ToppCelldroplet-Fat-BAT+GAT+MAT|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RPL36A RPS17 GSTA3 ANKRD11 SRPK3

1.27e-0419111354a201939e418f7268be09d59e08fc99f238a4136
ToppCelldroplet-Fat-BAT+GAT+MAT-30m|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RPL36A RPS17 GSTA3 ANKRD11 SRPK3

1.27e-041911135fa4e9ffdcde10b832d8ad2b6b4a704ac8b681e2e
ToppCellfacs-Lung-24m-Mesenchymal-fibroblast-alveolar_fibroblast|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

GSTA3 SORT1 TNFSF13B C3 PRKG2

1.27e-04191113580484d39f34703a33b9bac09826b7a526e883cab
ToppCellfacs-Lung-24m-Mesenchymal-fibroblast-alveolar_fibroblast-alveolar_fibroblast_l49|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

GSTA3 SORT1 TNFSF13B C3 PRKG2

1.27e-0419111355c4e4e9de14edfae072a2a2882220a31bebf51b2
ToppCellEpithelial-alveolar_epithelial_cell_type_1/2_(AT1/AT2-like)|World / Lineage, Cell type, age group and donor

ERBB3 ZNF608 CTNNA3 PRKG2 PATJ

1.27e-041911135d3733c8c4bda70c4390e5601fdda6188a64be944
ToppCell5'-GW_trimst-2-LargeIntestine-Epithelial-epithelial_progenitor_cell-Stem_cells|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

ERBB3 DSP RPS17 PATJ GP2

1.27e-041911135a8d77095ba20b47fc70ba04f80759fbce873253d
ToppCelldroplet-Large_Intestine-COLON_PROXIMAL-30m-Epithelial|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DSP APOB HNRNPUL1 PRRC2C ANKRD11

1.27e-04191113509db184cb90fe282a14474d7217068c58092c6f8
ToppCelldroplet-Large_Intestine-COLON_PROXIMAL-30m|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DSP APOB HNRNPUL1 PRRC2C ANKRD11

1.27e-041911135973117730d6ba5f127e7a0bfabfd0ff2ca7ac131
ToppCellCOVID-19_Severe-CD4+_Tcm|World / disease group, cell group and cell class

RPL36A RPS17 LPIN2 PRKCQ PATJ

1.30e-0419211353352f13a6e706991dcf3ec173587bb6aba36a385
ToppCellPCW_07-8.5-Epithelial-Epithelial_alveolar-distal|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

ERBB3 DSP AR CTNNA3 PATJ

1.30e-041921135b7c01e12b3e9be960a741b08835f1dfff65d0d47
ToppCellBAL-Mild|BAL / Compartment, Disease Groups and Clusters

CACNA1A TRIM34 TRAFD1 OASL C3

1.30e-0419211351a6cbf014d3f7a3fb6f53adab078c4742e7137de
ToppCellNeuron-Postmitotic-Inhibitory_Neuron-SST-MGE1-4|World / Primary Cells by Cluster

RPS17 JAKMIP2 ZNF608 EIF5 TMEM131L

1.33e-0419311352eb6e4cff4fe3ce564c1581f6f7df4834895aaa9
ToppCelldroplet-Bladder-nan-24m-Epithelial-basal_bladder_epithelial_cell_(Krt5+)|Bladder / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RPL36A DSP RPS17 GSTA3 LPIN2

1.36e-041941135c48de3b9c281345c8f65427703837dd921b01826
ToppCell5'-Adult-SmallIntestine-Epithelial-mature_enterocytic-Paneth|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

RPS17 APOB GALNT13 GSTA1 GP2

1.36e-0419411352f6e62a4ec8707bd5a16c0734c5131af55207ea2
ToppCellsystemic_lupus_erythematosus-flare-Lymphocytic-lymphocyte-male|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex

TCP11L1 POLA2 CDC7 PTCD2 PRKCQ

1.36e-0419411358f4b63b0b9a40765205e4ca6bd94a675a83dbe3d
ToppCellPCW_07-8.5-Epithelial|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

ERBB3 DSP AR CTNNA3 PATJ

1.36e-041941135f63ceedb88a9abc8644ee94adfd541e7817c1e3a
ToppCellPCW_07-8.5-Epithelial-Epithelial_airway|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

ERBB3 DSP AR CTNNA3 PATJ

1.36e-041941135f95c8dc242c9aebcadfe61b1ed033349cb7e5a88
ToppCell5'-GW_trimst-2-LargeIntestine-Epithelial-mature_enterocytic-Enterocyte|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

ERBB3 APOB GSTA1 CRYL1 PRKG2

1.36e-041941135fcbf9c4f3801ab1a34fcd62c752fabc97fc7bde1
ToppCelldroplet-Pancreas-PANCREAS-30m-Epithelial-pancreatic_B_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CACNA1A PEG3 TMEM215 PRRC2C ANKRD11

1.40e-0419511353e519cffa6144a62b06124642a14c9ff39b76554
ToppCelldroplet-Pancreas-PANCREAS-30m-Epithelial-pancreatic_B_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CACNA1A PEG3 TMEM215 PRRC2C ANKRD11

1.40e-0419511357796ea9247f4c63762f0de8490fed08b9717fa23
ToppCell5'-Parenchyma_lung-Epithelial-Epithelial_transtional|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

ERBB3 DSTN GSTA1 NCOA7 C3

1.43e-041961135982ed511edb3f802d8e6a46cd8e97f6482f49437
ToppCell5'-Parenchyma_lung-Epithelial-Epithelial_transtional-epithelial_cell_of_lung-Transitional_Club-AT2|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

ERBB3 DSTN GSTA1 NCOA7 C3

1.43e-0419611357e52c212e2b910f2f25fdbedc92fe1c9d3e2602f
ToppCellMild-CD4+_T_activated|World / Disease group and Cell class

SETX TRAFD1 OASL LPIN2 NCOA7

1.43e-041961135417b4fc2e4388f34c410576131b02936f93e46b6
ToppCell5'-Parenchyma_lung-Epithelial-Epithelial_transtional-epithelial_cell_of_lung|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

ERBB3 DSTN GSTA1 NCOA7 C3

1.43e-04196113514aa7a0cb905983ca98e05f8fa9a1c94f2031333
ToppCellLPS_anti-TNF-Epithelial_alveolar-AT_1-Differentiating_AT2|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type

TMC1 DSP LPIN2 C3 PATJ

1.46e-0419711353d13a4f2e86422900ee2194e8a1fd1cf9750d5d3
ToppCellwk_08-11-Epithelial-Distal_epithelial_progenitor-epi-tip_intermediate|wk_08-11 / Celltypes from embryonic and fetal-stage human lung

ERBB3 DSP PEG3 AR PATJ

1.50e-04198113584697f316d9195ebe838cf57f4dbdd9feea43bec
ToppCellTransverse-T_cell-Th17|T_cell / Region, Cell class and subclass

RPL36A CFL1 RPS17 HNRNPUL1 TNFSF13B

1.50e-041981135918068ffd682c896c11d576072bde270630539d9
ToppCellwk_08-11-Epithelial-Distal_epithelial_progenitor|wk_08-11 / Celltypes from embryonic and fetal-stage human lung

ERBB3 DSP PEG3 AR PATJ

1.50e-041981135eda85a592527992b51a00f288cff0c3239c47e6f
ToppCellNS-critical-LOC-Epithelial-Secretory_LYPD2|LOC / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

ERBB3 DSTN DSP GSTA1 C3

1.50e-0419811354a481e1edb80b950c823ed926842cd5132cfb27f
ToppCell5'-GW_trimst-1.5-SmallIntestine-Epithelial|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

ERBB3 DSP APOB GSTA1 CRYL1

1.50e-0419811358fbc461315986e357a0961a261ed10880637d6ad
ToppCell5'-Adult-SmallIntestine-Epithelial-epithelial_progenitor_cell-Stem_cells|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

ERBB3 RPS17 GALNT13 GSTA1 GP2

1.53e-041991135f544229f471b4717166dd4b588399afe45cc31b5
ToppCellBiopsy_IPF-Epithelial-SCGB3A2+_SCGB1A1+|Biopsy_IPF / Sample group, Lineage and Cell type

ERBB3 DSTN GSTA1 NCOA7 C3

1.53e-041991135c6150f5fe2ce4466149a4d553acb907034a72efb
ToppCellNS-critical-LOC-Epithelial|LOC / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

ERBB3 DSTN DSP TMPRSS11B GSTA1

1.53e-041991135d64adb68502be596ce55fb2cb63fe1cfa2c5f8ba
ToppCellfacs-Mammary_Gland-Mammary_Gland-3m-Epithelial-basal_cell|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RAN RPL36AL DSTN RPL36A RPS17

1.53e-0419911351b74f6fbf2628f335ba5eb49b679d2f72068bbbe
ToppCell390C-Lymphocytic-CD4_T-cell-CD4+_Naive_T_cell_/_CD4+_Trm_cell|CD4_T-cell / Donor, Lineage, Cell class and subclass (all cells)

RAN RPL36AL RPL36A CFL1 RPS17

1.53e-0419911350ef7f8e85d1402d72405ec58c6e5cc05d1cc339a
Diseasenemaline myopathy 7 (implicated_via_orthology)

DSTN CFL1

1.38e-0521102DOID:0110934 (implicated_via_orthology)
Diseasehip circumference

MCM6 SUCLG2 TMPRSS11B LIPC TRAFD1 LTN1 PATJ GP2

4.06e-053381108EFO_0005093
Diseasemyoglobinuria (implicated_via_orthology)

LPIN3 LPIN2

4.12e-0531102DOID:0080108 (implicated_via_orthology)
Diseaseobesity (implicated_via_orthology)

AR LPIN3 LIPC LPIN2 MED12L C3

1.59e-042151106DOID:9970 (implicated_via_orthology)
DiseaseAlzheimer's disease 1 (implicated_via_orthology)

KLC2 KLC1

2.86e-0471102DOID:0080348 (implicated_via_orthology)
Diseasecholesteryl ester 18:3 measurement

APOB SUCLG2 LIPC

4.50e-04401103EFO_0010346
DiseaseHead and Neck Carcinoma

ERBB3 CDC73

6.08e-04101102C3887461
Diseasebody surface area

ERBB3 TRAF3 TIAM2 ZNF608 TNFSF13B ANKRD11 NCOA7 PRKG2 PATJ

6.90e-046431109EFO_0022196
Diseaseplatelet crit

KALRN APOB FAM13B PXK GSTA1 CDC7 LPIN3 TRAFD1 CDK13 TNFSF13B TMEM131L

8.68e-0495211011EFO_0007985
Diseasekeratinocyte carcinoma

CFL1 RHOU ANKRD11 HERC2

1.01e-031181104EFO_0010176
DiseaseHyperlipoproteinemia Type IIb

APOB LIPC

1.05e-03131102C1704417
Diseaselow density lipoprotein triglyceride measurement

APOB LIPC

1.40e-03151102EFO_0009946
Diseasetriglycerides to total lipids in chylomicrons and extremely large VLDL percentage

APOB LIPC

1.40e-03151102EFO_0022328
Diseaselipid metabolism disorder (implicated_via_orthology)

LPIN3 LPIN2

1.40e-03151102DOID:3146 (implicated_via_orthology)
DiseaseInsulin Resistance

AR LIPC C3

1.48e-03601103C0021655
DiseaseInsulin Sensitivity

AR LIPC C3

1.48e-03601103C0920563
DiseaseHyperlipoproteinemia Type IIa

APOB LIPC

1.60e-03161102C0745103
Diseasesickle cell anemia (is_implicated_in)

APOB C3

1.60e-03161102DOID:10923 (is_implicated_in)
Diseasethyroxine measurement, triiodothyronine measurement

GALNT13 TIAM2

1.81e-03171102EFO_0005130, EFO_0008392
DiseaseLipidemias

APOB LIPC

1.81e-03171102C1706412
Diseaselevel of Sphingomyelin (d32:1) in blood serum

LIPC RABEP1

1.81e-03171102OBA_2045173
Diseasecholesterol to total lipids in chylomicrons and extremely large VLDL percentage

APOB LIPC

1.81e-03171102EFO_0022232
DiseaseHyperlipidemia

APOB LIPC

1.81e-03171102C0020473
DiseaseHypercholesterolemia, Familial

APOB LIPC

2.03e-03181102C0020445
Diseaseskin sensitivity to sun

ANKRD11 HERC2

2.26e-03191102EFO_0004795
Diseaselaryngeal squamous cell carcinoma (is_marker_for)

ERBB3 CDC73

2.26e-03191102DOID:2876 (is_marker_for)
DiseaseJT interval

FAM13B TTC7B CDK13 TNFSF13B NCOA7

2.41e-032481105EFO_0007885
Diseasethyroid peroxidase antibody measurement

KALRN GLG1 TMEM131L

2.49e-03721103EFO_0005666
Diseasetype 1 diabetes mellitus (is_marker_for)

APOB LIPC C3

2.49e-03721103DOID:9744 (is_marker_for)
Diseasecholesteryl esters to total lipids in chylomicrons and extremely large VLDL percentage

APOB LIPC

2.76e-03211102EFO_0022246
Diseasedocosahexaenoic acid to total fatty acids percentage

APOB LIPC

2.76e-03211102EFO_0022262
Diseaseprostate cancer (is_marker_for)

RAF1 ERBB3 AR CDK13

2.81e-031561104DOID:10283 (is_marker_for)
Diseaseneonatal abstinence syndrome

KALRN RHOU OXSR1

3.02e-03771103EFO_0005799
Diseaselymphocyte count

ERBB3 TRAF3 PDE6D KALRN SANBR PPID LIPC CDK13 RABEP1 TNFSF13B MED12L ANKRD11 C3

3.17e-03146411013EFO_0004587
Diseasespermatogenic failure (is_implicated_in)

AKAP3 MOV10L1

3.31e-03231102DOID:0111910 (is_implicated_in)
Diseasenephrotic syndrome (biomarker_via_orthology)

CFL1 APOB

3.60e-03241102DOID:1184 (biomarker_via_orthology)

Protein segments in the cluster

PeptideGeneStartEntry
NKRVCEEIAIIPSKK

RPS17

31

P08708
IKRLPKLKAVFDCVV

CACNA1A

1356

O00555
KIPVCIKVIEDKSGR

ERBB3

736

P21860
PEEVKKRKKAVLFCL

CFL1

26

P23528
KKIEEKRKILCCITP

ANKRD11

2446

Q6UB99
KKPRIEDEECVRLDK

CDC73

136

Q6P1J9
LDKRLVKDIAKVAPA

ACTRT3

306

Q9BYD9
SPIKCREALKLEEKK

C3

1586

P01024
PEEIKKRKKAVIFCL

DSTN

26

P60981
KEVEKKLRCLLADLP

CDK13

636

Q14004
ADCVKKVKEERPLFP

RAF1

586

P04049
LTKVTICKDREGKPK

RBM11

36

P57052
PIVLCGNKVDIKDRK

RAN

116

P62826
CRLFIGAIPKEKKKE

RBM46

141

Q8TBY0
KKADVEEEIKIPVVC

RABEP1

336

Q15276
VCPPEEKDAKLALIK

GSTA1

111

P08263
CAPKKEKVAIKRINL

OXSR1

36

O95747
LPEELCDLKKLRILD

LRRC69

191

Q6ZNQ3
RKKPLEDLVCKLADI

LTN1

586

O94822
REVIEKKPEVFKVAC

LPIN3

731

Q9BQK8
CRALKTFVKDRKEIP

MCM6

91

Q14566
ELLKRVRETEKQCKP

JAKMIP2

311

Q96AA8
AKDLLVKLFVREPEK

PRKCQ

606

Q04759
CEKLVKREKPRELIF

MED12L

681

Q86YW9
LKEPERLCTDKELIL

MED12L

1261

Q86YW9
PDRLRKCVEQKIDIL

MOV10L1

501

Q9BXT6
EKCIQDFLKIKIPDR

KCTD16

396

Q68DU8
KKLKVRDEPPEEICT

MTMR8

536

Q96EF0
DTICPKAPKLEERLK

GLRX3

226

O76003
EEPVDVEKMRKCLLK

HERC2

1646

O95714
IQRVPRIKLEKLKCD

KIAA2026

501

Q5HYC2
EKRIERCLPEDIKKM

FAM13B

686

Q9NYF5
LCRPEEKDAKIALIK

GSTA3

111

Q16772
EARVPKKILKCKAVS

PDE6D

46

O43924
QLDCGPREIKVKVDK

GP2

226

P55259
DIEKAVELMCLVPKR

KALRN

2086

O60229
LRPTQEKIFVKCEIK

LIPC

476

P11150
IKELDRIIACKRKNP

AR

836

P10275
KTTKKIVLRLECVEP

RPL36AL

61

Q969Q0
EKRILEELCSPFIVK

PRKG2

501

Q13237
VRAKKPENCEKLVTL

PEG3

106

Q9GZU2
AEPLCKRALEIREKV

KLC2

301

Q9H0B6
CVRKQLKKERPIILD

OASL

291

Q15646
LLARIKEDRKTVVCP

GALNT13

221

Q8IUC8
KVPIIVVGCKTDLRK

RHOD

121

O00212
KPLIKREKPEETCAA

CTNNA3

856

Q9UI47
REPKIQVSELCKKAI

GLG1

281

Q92896
ALEDKRVRLQPECKK

GLG1

1096

Q92896
LIKDLKSKEVPEARA

APOB

761

P04114
ELAKEIRVKAEPFIK

EIF5

366

P55010
VLKEKIFEEQPCLRK

CABIN1

196

Q9Y6J0
VDPILIKCLAEKLEE

GCNT4

416

Q9P109
EERKKPTEEEIRKIC

ANKZF1

371

Q9H8Y5
KEVPAQDLRKLCERL

CDC7

451

O00311
VPVIKKCIDILIEKE

CUL1

746

Q13616
DEETGLCLLPLKEKK

DSP

2436

P15924
IQECVPEDLELKKKI

CRYL1

91

Q9Y2S2
IRRLDKPKKLSAECA

IDE

891

P14735
DKRPPILECLEKLEK

RSF1

576

Q96T23
KDPRRCLEEGKLVNK

NDUFA8

51

P51970
KLDSACLLKPREVVE

PPRC1

421

Q5VV67
VKPADLKKRIESLID

CUL4B

881

Q13620
CLAPVDLVVKKELRA

HMCES

266

Q96FZ2
ELLCNKPEEEKALLV

CEBPZ

371

Q03701
EKAKKVVACELDPRL

DIMT1

76

Q9UNQ2
CLKVKPVVSQFLREK

FADS6

306

Q8N9I5
AEPLCKRALEIREKV

KLC1

316

Q07866
AKVREKVKDVPALVA

PTCD2

316

Q8WV60
RKAIVICPTDEDLKD

HNRNPUL1

526

Q9BUJ2
EKICRKEVKPLGLTV

PHYH

86

O14832
CAPARDEEVKKLKDI

TCP11L1

191

Q9NUJ3
GVNPVREVKDLKKKC

SORT1

726

Q99523
GEKLLLFCKEDRKVI

TRIM34

101

Q9BYJ4
VAKITPEKVCKFIRL

PSAPL1

351

Q6NUJ1
EKRLLKKHEETECPL

TRAFD1

71

O14545
ERELCPLKTSKKLPE

TMEM131L

1101

A2VDJ0
EKLLRELAEDCKRPL

FER1L5

621

A0AVI2
LKECLSLDPEERKKA

NCOA7

436

Q8NI08
KTTKKIVLRLECVEP

RPL36A

61

P83881
PIKACADKLKREIEL

LARS1

96

Q9P2J5
CIGKDAPIALKRKLE

FASTKD2

316

Q9NYY8
EVKGEKPAKLCVIAE

PPID

166

Q08752
CAEKLKRLDEKLGIL

PRRC2C

481

Q9Y520
DKPLKDVIIADCGKI

PPIB

191

P23284
EFCEIEVKKPKRKRS

SETX

1151

Q7Z333
QKLPDIREVLTCKIE

POLA2

211

Q14181
LKEEPVDVEKRKCLL

HERC2P3

371

Q9BVR0
KKLLTKETERRIPCI

SANBR

331

Q6NSI8
NEKCREPVLRKDLKE

TRAF5

141

O00463
VDEIKLLKCVRDSDP

SRPK3

121

Q9UPE1
LDEKRQIIATVKCKP

TMC1

96

Q8TDI8
KVPEQPVKEDRKLCE

AKAP3

616

O75969
VLIELDKCKEKPVPE

RHOU

171

Q7L0Q8
ITKACRELELKVPLV

SUCLG2

376

Q96I99
PDCKEKVLRKDLRDH

TRAF3

151

Q13114
IRVLICEEKAPVLKM

WDR48

286

Q8TAF3
PCFRKPKDKEVVELL

TMEM215

81

Q68D42
HIKCELPLEKTCKDR

TIAM2

1461

Q8IVF5
PCVVLTRVKEKEGKV

SPEN

876

Q96T58
IRKICLPEAKMKLSE

TMPRSS11B

286

Q86T26
ERKEKKERIPVFCID

SNX14

581

Q9Y5W7
SPEVKIVELVKDCKG

PATJ

681

Q8NI35
LVKKMCRKAPDVVDD

WDR97

766

A6NE52
KPIICISAEEKIQRK

TTC41P

1186

Q6P2S7
IPTKLKEALRIAKEC

PXK

411

Q7Z7A4
EVKALLEKVPAELIC

WDR46

501

O15213
PELCKALVKEKLRLD

PIAS4

296

Q8N2W9
AVSKPDLIICLEKEK

ZNF726

46

A6NNF4
KDCDLEKREPPLKFI

XPA

151

P23025
AVKVLKECIRLKPDD

TTC7B

416

Q86TV6
DVLKCCLKRDPKQRI

TTK

766

P33981
DCERKSELPLKELGK

ZNF608

1126

Q9ULD9
EDRELVLRKDCPKIV

ZSCAN9

196

O15535
EMKLKECVSILPRKE

TNFSF13B

21

Q9Y275
LICPEGVLKRKKEDF

ZNF662

81

Q6ZS27
REVIEKKPEKFKIEC

LPIN2

776

Q92539