Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	intramolecular oxidoreductase activity, transposing S-S bonds	PDIA4 TXNDC2 PDILT	9.55e-06	22	38	3	GO:0016864
GeneOntologyMolecularFunction	protein disulfide isomerase activity	PDIA4 TXNDC2 PDILT	9.55e-06	22	38	3	GO:0003756
GeneOntologyMolecularFunction	intramolecular oxidoreductase activity	PDIA4 TXNDC2 PDILT	1.73e-04	57	38	3	GO:0016860
GeneOntologyMolecularFunction	lysine-acetylated histone binding	KMT2A ZZZ3	1.48e-03	30	38	2	GO:0070577
GeneOntologyMolecularFunction	acetylation-dependent protein binding	KMT2A ZZZ3	1.58e-03	31	38	2	GO:0140033
GeneOntologyMolecularFunction	protein-disulfide reductase activity	PDIA4 TXNDC2	2.13e-03	36	38	2	GO:0015035
GeneOntologyMolecularFunction	disulfide oxidoreductase activity	PDIA4 TXNDC2	3.03e-03	43	38	2	GO:0015036
GeneOntologyMolecularFunction	oxidoreductase activity, acting on a sulfur group of donors	PDIA4 TXNDC2	5.27e-03	57	38	2	GO:0016667
GeneOntologyMolecularFunction	isomerase activity	PDIA4 TXNDC2 PDILT	5.77e-03	192	38	3	GO:0016853
GeneOntologyMolecularFunction	RNA polymerase binding	ERCC6 WAC	6.80e-03	65	38	2	GO:0070063
GeneOntologyMolecularFunction	basal RNA polymerase II transcription machinery binding	NOLC1 WAC	7.01e-03	66	38	2	GO:0001099
GeneOntologyMolecularFunction	basal transcription machinery binding	NOLC1 WAC	7.01e-03	66	38	2	GO:0001098
GeneOntologyBiologicalProcess	regulation of hydrogen peroxide catabolic process	HP NNT	1.98e-05	4	38	2	GO:2000295
HumanPheno	Wide nasal bridge	KMT2A LTBP1 SIN3A ERCC6 TCOF1 WAC TRPS1	4.78e-05	508	12	7	HP:0000431
HumanPheno	Contracture of the distal interphalangeal joint of the fingers	KMT2A SIN3A	7.59e-05	6	12	2	HP:0009697
HumanPheno	Dilatation of renal calices	KMT2A WAC	7.59e-05	6	12	2	HP:0100581
HumanPheno	Abnormal renal calyx morphology	KMT2A WAC	7.59e-05	6	12	2	HP:0011130
HumanPheno	Ivory epiphyses of the phalanges of the hand	ERCC6 TRPS1	7.59e-05	6	12	2	HP:0010234
HumanPheno	Sclerosis of finger phalanx	ERCC6 TRPS1	1.41e-04	8	12	2	HP:0100899
HumanPheno	Ivory epiphyses	ERCC6 TRPS1	1.81e-04	9	12	2	HP:0010583
HumanPheno	Branchial fistula	SIN3A TCOF1	2.27e-04	10	12	2	HP:0009795
MousePheno	zygomatic arch hypoplasia	TCOF1 TRPS1	4.16e-06	2	29	2	MP:0030377
MousePheno	short maxilla	LTBP1 TCOF1 TRPS1	6.98e-05	39	29	3	MP:0000097
MousePheno	skin photosensitivity	ERCC6 FECH	8.67e-05	7	29	2	MP:0001202
MousePheno	delayed tooth eruption	ENAM TRPS1	1.85e-04	10	29	2	MP:0003053
MousePheno	abnormal maxilla morphology	ENAM LTBP1 TCOF1 TRPS1	2.10e-04	144	29	4	MP:0000455
MousePheno	small maxilla	LTBP1 TCOF1 TRPS1	2.41e-04	59	29	3	MP:0004540
MousePheno	abnormal erythrocyte cell number	MKI67 ENAM KMT2A DIDO1 RAB5A FECH	2.96e-04	457	29	6	MP:0001586
MousePheno	short mandible	LTBP1 TCOF1 TRPS1	3.07e-04	64	29	3	MP:0000088
MousePheno	vertebral fusion	KMT2A TCOF1 WAC NPAT	3.37e-04	163	29	4	MP:0004609
MousePheno	abnormal zygomatic arch morphology	TCOF1 TRPS1	3.72e-04	14	29	2	MP:0004469
MousePheno	fused joints	KMT2A TCOF1 WAC NPAT	3.95e-04	170	29	4	MP:0003189
MousePheno	abnormal mandible morphology	ENAM LTBP1 TCOF1 TRPS1	4.51e-04	176	29	4	MP:0000458
MousePheno	small basisphenoid bone	LTBP1 TRPS1	4.90e-04	16	29	2	MP:0004462
MousePheno	rib fusion	KMT2A TCOF1 NPAT	5.50e-04	78	29	3	MP:0000154
Domain	THIOREDOXIN_1	PDIA4 TXNDC2 PDILT	1.60e-05	25	37	3	PS00194
Domain	LisH	NOLC1 TCOF1 NPAT	2.27e-05	28	37	3	IPR006594
Domain	LisH	NOLC1 TCOF1 NPAT	2.27e-05	28	37	3	SM00667
Domain	LISH	NOLC1 TCOF1 NPAT	2.27e-05	28	37	3	PS50896
Domain	Thioredoxin	PDIA4 TXNDC2 PDILT	3.10e-05	31	37	3	PF00085
Domain	Thioredoxin_domain	PDIA4 TXNDC2 PDILT	7.24e-05	41	37	3	IPR013766
Domain	THIOREDOXIN_2	PDIA4 TXNDC2 PDILT	8.36e-05	43	37	3	PS51352
Domain	Thioredoxin	PDIA4 TXNDC2	2.94e-04	13	37	2	IPR005746
Domain	PHD	KMT2A DIDO1 INTS12	4.38e-04	75	37	3	PF00628
Domain	Znf_PHD-finger	KMT2A DIDO1 INTS12	5.10e-04	79	37	3	IPR019787
Domain	PHD	KMT2A DIDO1 INTS12	7.23e-04	89	37	3	SM00249
Domain	Znf_PHD	KMT2A DIDO1 INTS12	7.71e-04	91	37	3	IPR001965
Domain	ZF_PHD_2	KMT2A DIDO1 INTS12	8.74e-04	95	37	3	PS50016
Domain	ZF_PHD_1	KMT2A DIDO1 INTS12	9.01e-04	96	37	3	PS01359
Domain	-	PDIA4 TXNDC2 PDILT	1.80e-03	122	37	3	3.40.30.10
Domain	Thioredoxin-like_fold	PDIA4 TXNDC2 PDILT	2.25e-03	132	37	3	IPR012336
Domain	Znf_FYVE_PHD	KMT2A DIDO1 INTS12	3.05e-03	147	37	3	IPR011011
Domain	ER_TARGET	PDIA4 PDILT	3.90e-03	47	37	2	PS00014
Domain	Zinc_finger_PHD-type_CS	DIDO1 INTS12	7.34e-03	65	37	2	IPR019786
Pubmed	Menin and Menin-Associated Proteins Coregulate Cancer Energy Metabolism.	MKI67 NOLC1 KMT2A DIDO1 SIN3A TCOF1 RSL1D1 WAC TRPS1	1.58e-10	341	40	9	32971831
Pubmed	Human transcription factor protein interaction networks.	MKI67 PDIA4 NOLC1 SLX4IP KMT2A DIDO1 SIN3A ZZZ3 INTS12 RSL1D1 KIFC1 TRPS1 NPAT	3.84e-09	1429	40	13	35140242
Pubmed	Functional proteomics establishes the interaction of SIRT7 with chromatin remodeling complexes and expands its role in regulation of RNA polymerase I transcription.	MKI67 PDIA4 NOLC1 KMT2A DIDO1 EIF4G3 TCOF1 NNT RSL1D1	4.47e-08	653	40	9	22586326
Pubmed	The Nse5/6-like SIMC1-SLF2 complex localizes SMC5/6 to viral replication centers.	MKI67 NOLC1 SLX4IP KMT2A DIDO1 ZZZ3 RSL1D1 KIFC1 WAC NPAT	9.24e-08	954	40	10	36373674
Pubmed	A probability-based approach for high-throughput protein phosphorylation analysis and site localization.	MKI67 NOLC1 DIDO1 ERCC6 EIF4G3 TCOF1 RSL1D1 WAC	9.28e-08	503	40	8	16964243
Pubmed	NuRD subunit CHD4 regulates super-enhancer accessibility in rhabdomyosarcoma and represents a general tumor dependency.	MKI67 NOLC1 KMT2A TCOF1 RSL1D1	1.25e-07	103	40	5	32744500
Pubmed	The E3 ubiquitin ligase HECTD1 contributes to cell proliferation through an effect on mitosis.	MKI67 NOLC1 DIDO1 SIN3A ERCC6 EIF4G3 RSL1D1 KIFC1 NEMF	1.60e-07	759	40	9	35915203
Pubmed	PRISMA and BioID disclose a motifs-based interactome of the intrinsically disordered transcription factor C/EBPα.	MKI67 PDIA4 NOLC1 KMT2A DIDO1 SIN3A INTS12 RSL1D1 KIFC1 WAC	3.52e-07	1103	40	10	34189442
Pubmed	The in vivo Interaction Landscape of Histones H3.1 and H3.3.	MKI67 KMT2A DIDO1 SIN3A ERCC6 INTS12 KIFC1 NPAT	3.91e-07	608	40	8	36089195
Pubmed	Proximity-dependent Mapping of the Androgen Receptor Identifies Kruppel-like Factor 4 as a Functional Partner.	KMT2A SIN3A INTS12 KIFC1 WAC TRPS1	6.10e-07	268	40	6	33640491
Pubmed	Proteomic characterization of chromosomal common fragile site (CFS)-associated proteins uncovers ATRX as a regulator of CFS stability.	MKI67 NOLC1 SLX4IP DIDO1 TCOF1 HP NNT RSL1D1	6.62e-07	652	40	8	31180492
Pubmed	N-Terminal Acetyltransferase Naa40p Whereabouts Put into N-Terminal Proteoform Perspective.	MKI67 NOLC1 KMT2A DIDO1 SIN3A EIF4G3 TCOF1 RSL1D1 WAC	9.05e-07	934	40	9	33916271
Pubmed	H4K20me0 recognition by BRCA1-BARD1 directs homologous recombination to sister chromatids.	MKI67 NOLC1 KMT2A DIDO1 SIN3A ZZZ3 INTS12 TCOF1 RSL1D1 WAC	1.50e-06	1294	40	10	30804502
Pubmed	The ubiquitin ligase Uhrf2 is a master regulator of cholesterol biosynthesis and is essential for liver regeneration.	MKI67 NOLC1 KMT2A INTS12	2.98e-06	86	40	4	37253089
Pubmed	Phosphorylation of proteins by inositol pyrophosphates.	NOLC1 TCOF1	3.87e-06	3	40	2	15604408
Pubmed	Haploinsufficiency of MeCP2-interacting transcriptional co-repressor SIN3A causes mild intellectual disability by affecting the development of cortical integrity.	MKI67 SIN3A	7.73e-06	4	40	2	27399968
Pubmed	Recruitment of the Mammalian Histone-modifying EMSY Complex to Target Genes Is Regulated by ZNF131.	KMT2A LTBP1 SIN3A NPAT	7.93e-06	110	40	4	26841866
Pubmed	SMYD3 Impedes Small Cell Lung Cancer Sensitivity to Alkylation Damage through RNF113A Methylation-Phosphorylation Cross-talk.	MKI67 NOLC1 SIN3A TCOF1 RSL1D1 FECH TRPS1	8.84e-06	655	40	7	35819319
Pubmed	Cross-linking mass spectrometry reveals the structural topology of peripheral NuRD subunits relative to the core complex.	SIN3A MAP6 TRPS1	1.16e-05	38	40	3	33283408
Pubmed	Differential Mitochondrial Requirements for Radially and Non-radially Migrating Cortical Neurons: Implications for Mitochondrial Disorders.	MKI67 NNT	1.29e-05	5	40	2	27050514
Pubmed	Trps1 Regulates Development of Craniofacial Skeleton and Is Required for the Initiation of Palatal Shelves Fusion.	MKI67 TRPS1	1.29e-05	5	40	2	31130868
Pubmed	MYC multimers shield stalled replication forks from RNA polymerase.	MKI67 NOLC1 DIDO1 SIN3A TCOF1 RSL1D1 RAB5A KIFC1	1.42e-05	989	40	8	36424410
Pubmed	BioID identifies novel c-MYC interacting partners in cultured cells and xenograft tumors.	KMT2A DIDO1 SIN3A WAC	1.73e-05	134	40	4	25452129
Pubmed	HIV-1 Vpr induces cell cycle arrest and enhances viral gene expression by depleting CCDC137.	MKI67 NOLC1 TCOF1 RSL1D1	2.55e-05	148	40	4	32538781
Pubmed	Large-scale characterization of HeLa cell nuclear phosphoproteins.	MKI67 NOLC1 KMT2A DIDO1 SIN3A TCOF1 RSL1D1	2.59e-05	774	40	7	15302935
Pubmed	HRG1 is essential for heme transport from the phagolysosome of macrophages during erythrophagocytosis.	LAMP3 FECH	2.70e-05	7	40	2	23395172
Pubmed	The Role of Epithelial Stat3 in Amelogenesis during Mouse Incisor Renewal.	MKI67 ENAM	2.70e-05	7	40	2	29550820
Pubmed	Trps1 and its target gene Sox9 regulate epithelial proliferation in the developing hair follicle and are associated with hypertrichosis.	MKI67 TRPS1	2.70e-05	7	40	2	23133399
Pubmed	E2F activation of S phase promoters via association with HCF-1 and the MLL family of histone H3K4 methyltransferases.	KMT2A SIN3A	2.70e-05	7	40	2	17612494
Pubmed	MYC Protein Interactome Profiling Reveals Functionally Distinct Regions that Cooperate to Drive Tumorigenesis.	KMT2A DIDO1 SIN3A RSL1D1 NPAT	4.25e-05	339	40	5	30415952
Pubmed	Systematic analysis of human protein complexes identifies chromosome segregation proteins.	MKI67 PDIA4 NOLC1 HP RSL1D1 KIFC1 FECH TRPS1	4.31e-05	1155	40	8	20360068
Pubmed	Leukemia proto-oncoprotein MLL forms a SET1-like histone methyltransferase complex with menin to regulate Hox gene expression.	KMT2A SIN3A	4.62e-05	9	40	2	15199122
Pubmed	Interaction network of human early embryonic transcription factors.	MKI67 PDIA4 KMT2A ZZZ3 TRPS1	5.01e-05	351	40	5	38297188
Pubmed	A higher-order complex containing AF4 and ENL family proteins with P-TEFb facilitates oncogenic and physiologic MLL-dependent transcription.	KMT2A SIN3A	5.77e-05	10	40	2	20153263
Pubmed	Transcription factor epiprofin is essential for tooth morphogenesis by regulating epithelial cell fate and tooth number.	MKI67 ENAM	5.77e-05	10	40	2	18156176
Pubmed	PI3K-mediated PDGFRα signaling regulates survival and proliferation in skeletal development through p53-dependent intracellular pathways.	MKI67 TCOF1	5.77e-05	10	40	2	24788519
Pubmed	RECQ1 helicase is involved in replication stress survival and drug resistance in multiple myeloma.	TCOF1 HP RSL1D1 KIFC1	5.85e-05	183	40	4	28186131
Pubmed	Human CpG binding protein interacts with MLL1, MLL2 and hSet1 and regulates Hox gene expression.	KMT2A KIFC1	7.05e-05	11	40	2	18082152
Pubmed	HSP27 and HSP70 interact with CD10 in C4-2 prostate cancer cells.	NOLC1 NNT FECH	7.31e-05	70	40	3	17342744
Pubmed	Phosphoproteome analysis of the human mitotic spindle.	MKI67 KMT2A ERCC6 RSL1D1	9.96e-05	210	40	4	16565220
Pubmed	BAP1 regulation of the key adaptor protein NCoR1 is critical for γ-globin gene repression.	MKI67 NOLC1 KMT2A DIDO1 TCOF1 RSL1D1 RAB5A FECH	1.09e-04	1318	40	8	30463901
Pubmed	PTENα and PTENβ promote carcinogenesis through WDR5 and H3K4 trimethylation.	MKI67 KMT2A SIN3A RSL1D1	1.13e-04	217	40	4	31685992
Pubmed	Cell-fate determination by ubiquitin-dependent regulation of translation.	NOLC1 TCOF1	1.16e-04	14	40	2	26399832
Pubmed	The protein interaction landscape of the human CMGC kinase group.	DIDO1 OCEL1 FAM90A1 TCOF1 RSL1D1 TRPS1	1.34e-04	695	40	6	23602568
Pubmed	Multisite dependency of an E3 ligase controls monoubiquitylation-dependent cell fate decisions.	NOLC1 TCOF1	1.34e-04	15	40	2	29999490
Pubmed	A point mutation in the Pdia6 gene results in loss of pancreatic β-cell identity causing overt diabetes.	MKI67 PDIA4	1.34e-04	15	40	2	34487921
Pubmed	Identifying biological pathways that underlie primordial short stature using network analysis.	MKI67 PDIA4 NOLC1 TCOF1 NNT RSL1D1 KIFC1	1.50e-04	1024	40	7	24711643
Pubmed	The human protein disulfide isomerase gene family.	PDIA4 PDILT	1.53e-04	16	40	2	23245351
Pubmed	Constraint of gene expression by the chromatin remodelling protein CHD4 facilitates lineage specification.	MKI67 SIN3A	1.53e-04	16	40	2	26116663
Pubmed	Chondroitin sulfate synthase 1 (Chsy1) is required for bone development and digit patterning.	MKI67 TRPS1	1.73e-04	17	40	2	22280990
Pubmed	Coregulator Sin3a Promotes Postnatal Murine β-Cell Fitness by Regulating Genes in Ca2+ Homeostasis, Cell Survival, Vesicle Biosynthesis, Glucose Metabolism, and Stress Response.	MKI67 SIN3A	1.73e-04	17	40	2	32245798
Pubmed	A Functional Switch of NuRD Chromatin Remodeling Complex Subunits Regulates Mouse Cortical Development.	MKI67 SIN3A	1.73e-04	17	40	2	27806305
Pubmed	Identification of proteins associated with ligand-activated estrogen receptor α in human breast cancer cell nuclei by tandem affinity purification and nano LC-MS/MS.	MKI67 EIF4G3 TCOF1 RSL1D1	1.80e-04	245	40	4	21182205
Pubmed	Gain of Additional BIRC3 Protein Functions through 3'-UTR-Mediated Protein Complex Formation.	MKI67 PDIA4 NOLC1 TCOF1 NNT RSL1D1 KIFC1 NEMF	1.86e-04	1425	40	8	30948266
Pubmed	Lung epithelial tip progenitors integrate glucocorticoid- and STAT3-mediated signals to control progeny fate.	MKI67 LAMP3	1.95e-04	18	40	2	27578791
Pubmed	The multi-subunit GID/CTLH E3 ubiquitin ligase promotes cell proliferation and targets the transcription factor Hbp1 for degradation.	MKI67 NOLC1 SIN3A RSL1D1	2.03e-04	253	40	4	29911972
Pubmed	Construction of long-transcript enriched cDNA libraries from submicrogram amounts of total RNAs by a universal PCR amplification method.	PDIA4 NOLC1 DIDO1 MAP6 RSL1D1 FECH NPAT	2.13e-04	1084	40	7	11544199
Pubmed	Npat-dependent programmed Sertoli cell proliferation is indispensable for testis cord development and germ cell mitotic arrest.	MKI67 NPAT	2.18e-04	19	40	2	31084574
Pubmed	An endoplasmic reticulum stress regulator, Tmbim6, modulates secretory stage of mice molar.	MKI67 ENAM	2.42e-04	20	40	2	30963569
Pubmed	CHK2-BRCA1 tumor-suppressor axis restrains oncogenic Aurora-A kinase to ensure proper mitotic microtubule assembly.	MKI67 PDIA4 NOLC1 TCOF1 KIFC1	2.47e-04	494	40	5	26831064
Pubmed	Systematic bromodomain protein screens identify homologous recombination and R-loop suppression pathways involved in genome integrity.	NOLC1 SIN3A ZZZ3 ERCC6 TCOF1 FECH TRPS1	2.54e-04	1116	40	7	31753913
Pubmed	The RNA-mediated estrogen receptor α interactome of hormone-dependent human breast cancer cell nuclei.	KMT2A DIDO1 ERCC6 INTS12 EIF4G3 NMT2 KIFC1 TRPS1	2.60e-04	1497	40	8	31527615
Pubmed	Unbiased Identification of trans Regulators of ADAR and A-to-I RNA Editing.	MKI67 DIDO1 SIN3A TCOF1	2.64e-04	271	40	4	32433965
Pubmed	Control of a neuronal morphology program by an RNA-binding zinc finger protein, Unkempt.	SIN3A RAB5A WAC NPAT	2.64e-04	271	40	4	25737280
Pubmed	ALL-1 is a histone methyltransferase that assembles a supercomplex of proteins involved in transcriptional regulation.	KMT2A SIN3A	2.67e-04	21	40	2	12453419
Pubmed	ATP6AP2 variant impairs CNS development and neuronal survival to cause fulminant neurodegeneration.	MKI67 RAB5A	2.67e-04	21	40	2	30985297
Pubmed	Concomitant inactivation of foxo3a and fancc or fancd2 reveals a two-tier protection from oxidative stress-induced hydrocephalus.	MKI67 KIFC1	2.67e-04	21	40	2	24483844
Pubmed	Sin3a regulates epithelial progenitor cell fate during lung development.	MKI67 SIN3A	2.67e-04	21	40	2	28619823
Pubmed	Nuclear actin interactome analysis links actin to KAT14 histone acetyl transferase and mRNA splicing.	MKI67 NOLC1 ZZZ3 TCOF1 WAC	2.76e-04	506	40	5	30890647
Pubmed	The HECT type ubiquitin ligase NEDL2 is degraded by anaphase-promoting complex/cyclosome (APC/C)-Cdh1, and its tight regulation maintains the metaphase to anaphase transition.	KMT2A DIDO1 ZZZ3 ERCC6	3.03e-04	281	40	4	24163370
Pubmed	Epithelial-derived gasdermin D mediates nonlytic IL-1β release during experimental colitis.	RAB5A VPS4B	3.21e-04	23	40	2	32597834
Pubmed	Xrcc4 physically links DNA end processing by polynucleotide kinase to DNA ligation by DNA ligase IV.	NOLC1 TCOF1	3.80e-04	25	40	2	15385968
Pubmed	ZNF750 Regulates Skin Barrier Function by Driving Cornified Envelope and Lipid Processing Pathways.	SPRR4 MKI67	3.80e-04	25	40	2	37660780
Pubmed	Characterization and evolution of the novel gene family FAM90A in primates originated by multiple duplication and rearrangement events.	FAM90A2P FAM90A1	3.80e-04	25	40	2	17684299
Pubmed	Quantitative interaction proteomics and genome-wide profiling of epigenetic histone marks and their readers.	DIDO1 SIN3A ZZZ3	3.97e-04	124	40	3	20850016
Pubmed	SRCAP complex promotes lung cancer progression by reprograming the oncogenic transcription of Hippo-YAP/TAZ signaling pathway.	KMT2A DIDO1 SIN3A ZZZ3 TCOF1	4.01e-04	549	40	5	38280479
Pubmed	TNF deficiency causes alterations in the spatial organization of neurogenic zones and alters the number of microglia and neurons in the cerebral cortex.	MKI67 NNT	4.45e-04	27	40	2	31505254
Pubmed	Connecting the Dots in the Neuroglobin-Protein Interaction Network of an Unstressed and Ferroptotic Cell Death Neuroblastoma Model.	PDIA4 NOLC1 HP	5.09e-04	135	40	3	31405213
Pubmed	The interactome of the histone gene regulatory factor HiNF-P suggests novel cell cycle related roles in transcriptional control and RNA processing.	MKI67 NPAT	5.13e-04	29	40	2	17577209
Pubmed	MLL1 is essential for retinal neurogenesis and horizontal inner neuron integrity.	MKI67 KMT2A	5.13e-04	29	40	2	30093671
Pubmed	Elucidation of the BMI1 interactome identifies novel regulatory roles in glioblastoma.	MKI67 DIDO1 EIF4G3 RSL1D1	5.49e-04	329	40	4	34316702
Pubmed	Failure of epithelial tube maintenance causes hydrocephalus and renal cysts in Dlg5-/- mice.	MKI67 RAB5A	5.87e-04	31	40	2	17765678
Pubmed	Chr21 protein-protein interactions: enrichment in proteins involved in intellectual disability, autism, and late-onset Alzheimer's disease.	EIF4G3 TCOF1 RSL1D1 NMT2 WAC NEMF TRPS1	5.92e-04	1285	40	7	35914814
Pubmed	FBW7 suppresses ovarian cancer development by targeting the N6-methyladenosine binding protein YTHDF2.	KMT2A DIDO1 RSL1D1 NEMF FECH	6.05e-04	601	40	5	33658012
Pubmed	CHD3 and CHD4 form distinct NuRD complexes with different yet overlapping functionality.	MKI67 NOLC1 KMT2A TCOF1 RSL1D1	6.23e-04	605	40	5	28977666
Pubmed	Proteomic analysis of complexes formed by human topoisomerase I.	MKI67 TCOF1	6.26e-04	32	40	2	15848144
Pubmed	Use of RDA analysis of knockout mice to identify myeloid genes regulated in vivo by PU.1 and C/EBPalpha.	CSF2RB HP	6.26e-04	32	40	2	9611252
Pubmed	The DNA sequence and comparative analysis of human chromosome 10.	MKI67 ERCC6 NMT2 WAC	6.56e-04	345	40	4	15164054
Pubmed	Lhx2 is a direct NF-κB target gene that promotes primary hair follicle placode down-growth.	MKI67 TRPS1	6.66e-04	33	40	2	26952977
Pubmed	Systematic screening reveals a role for BRCA1 in the response to transcription-associated DNA damage.	MKI67 ZZZ3 RSL1D1	6.78e-04	149	40	3	25184681
Pubmed	TBK1 phosphorylation activates LIR-dependent degradation of the inflammation repressor TNIP1.	MKI67 PDIA4 NOLC1 TCOF1 RSL1D1 KIFC1	7.06e-04	949	40	6	36574265
Pubmed	A genome-wide association study in 19 633 Japanese subjects identified LHX3-QSOX2 and IGF1 as adult height loci.	LTBP1 SIN3A	7.07e-04	34	40	2	20189936
Pubmed	SLX4IP acts with SLX4 and XPF-ERCC1 to promote interstrand crosslink repair.	SLX4IP MAP6	7.07e-04	34	40	2	31495888
Pubmed	Compartmentalization of the SUMO/RNF4 pathway by SLX4 drives DNA repair.	MKI67 SLX4IP DIDO1 ZZZ3	7.45e-04	357	40	4	37059091
Pubmed	A protein interaction landscape of breast cancer.	MKI67 LTBP1 TCOF1 NNT RSL1D1	7.69e-04	634	40	5	34591612
Pubmed	Analysis of Ku70 S155 Phospho-Specific BioID2 Interactome Identifies Ku Association with TRIP12 in Response to DNA Damage.	KMT2A INTS12 KIFC1	7.74e-04	156	40	3	37108203
Pubmed	Targeted ubiquitination and degradation of G-protein-coupled receptor kinase 5 by the DDB1-CUL4 ubiquitin ligase complex.	NOLC1 SIN3A TCOF1	7.74e-04	156	40	3	22952844
Pubmed	Genetic Screens Reveal FEN1 and APEX2 as BRCA2 Synthetic Lethal Targets.	MKI67 KMT2A ERCC6	7.89e-04	157	40	3	30686591
Pubmed	Proximity biotinylation and affinity purification are complementary approaches for the interactome mapping of chromatin-associated protein complexes.	KMT2A LTBP1 RSL1D1 RAB5A KIFC1	8.31e-04	645	40	5	25281560
Pubmed	Proteome-wide identification of HSP70/HSC70 chaperone clients in human cells.	SPRR4 PDIA4 NOLC1 SIN3A TCOF1 NNT RSL1D1	8.53e-04	1367	40	7	32687490
Interaction	FAM90A26 interactions	FAM90A1 FAM90A26	3.65e-06	2	39	2	int:FAM90A26
Interaction	ZBTB38 interactions	MYBPH ERCC6 TCOF1 WAC NEMF	8.51e-06	145	39	5	int:ZBTB38
Interaction	SIRT7 interactions	MKI67 PDIA4 NOLC1 KMT2A DIDO1 EIF4G3 TCOF1 NNT RSL1D1	9.50e-06	744	39	9	int:SIRT7
Interaction	HECTD1 interactions	MKI67 NOLC1 DIDO1 SIN3A ERCC6 EIF4G3 RSL1D1 KIFC1 NEMF FECH	1.28e-05	984	39	10	int:HECTD1
Interaction	SMC5 interactions	MKI67 NOLC1 SLX4IP KMT2A DIDO1 ZZZ3 RSL1D1 KIFC1 WAC NPAT	1.47e-05	1000	39	10	int:SMC5
Interaction	MEN1 interactions	MKI67 NOLC1 KMT2A DIDO1 SIN3A ERCC6 TCOF1 RSL1D1 WAC TRPS1	1.89e-05	1029	39	10	int:MEN1
Interaction	H2BC5 interactions	MKI67 PDIA4 NOLC1 KMT2A TCOF1 NEMF	3.88e-05	331	39	6	int:H2BC5
Interaction	UHRF2 interactions	MKI67 NOLC1 KMT2A DIDO1 INTS12	4.01e-05	200	39	5	int:UHRF2
Interaction	H3C3 interactions	MKI67 KMT2A DIDO1 SIN3A INTS12 KIFC1 NPAT	4.02e-05	495	39	7	int:H3C3
Interaction	H2BC13 interactions	MKI67 PDIA4 NOLC1 KMT2A TCOF1	5.05e-05	210	39	5	int:H2BC13
Interaction	CSNK2A2 interactions	MKI67 NOLC1 KMT2A SIN3A ERCC6 FAM90A1 TCOF1 NMT2	5.77e-05	718	39	8	int:CSNK2A2
Interaction	SNX29 interactions	PDIA4 LAMP3 RAB5A	7.30e-05	42	39	3	int:SNX29
Interaction	H3-3A interactions	MKI67 KMT2A DIDO1 SIN3A ERCC6 INTS12 KIFC1 NPAT	7.76e-05	749	39	8	int:H3-3A
Interaction	TERF2IP interactions	MKI67 SLX4IP KMT2A DIDO1 ZZZ3 KIFC1 NPAT	8.00e-05	552	39	7	int:TERF2IP
Interaction	NAA40 interactions	MKI67 NOLC1 KMT2A DIDO1 SIN3A EIF4G3 TCOF1 RSL1D1 WAC	8.17e-05	978	39	9	int:NAA40
Interaction	CEBPA interactions	MKI67 PDIA4 NOLC1 KMT2A DIDO1 SIN3A INTS12 RSL1D1 KIFC1 WAC	9.54e-05	1245	39	10	int:CEBPA
Interaction	NOP56 interactions	MKI67 PDIA4 NOLC1 ERCC6 TCOF1 RSL1D1 NEMF	9.77e-05	570	39	7	int:NOP56
Interaction	APEX1 interactions	PDIA4 NOLC1 KMT2A DIDO1 OCEL1 SIN3A EIF4G3 TCOF1 RSL1D1 TRPS1	1.13e-04	1271	39	10	int:APEX1
Interaction	CXXC1 interactions	MKI67 KMT2A ZZZ3 KIFC1	1.21e-04	132	39	4	int:CXXC1
Interaction	KLF16 interactions	NOLC1 SIN3A INTS12 RSL1D1 TRPS1 NPAT	1.54e-04	425	39	6	int:KLF16
Interaction	NUP43 interactions	MKI67 KMT2A CCDC168 ZZZ3 EIF4G3 RSL1D1 NPAT	1.73e-04	625	39	7	int:NUP43
Interaction	ARL4D interactions	MKI67 NOLC1 TCOF1 RSL1D1	1.79e-04	146	39	4	int:ARL4D
Interaction	CUL7 interactions	MKI67 PDIA4 NOLC1 ERCC6 TCOF1 NNT RSL1D1 TRPS1	1.79e-04	845	39	8	int:CUL7
Interaction	NSD2 interactions	MKI67 SIN3A TCOF1 HP RSL1D1	1.89e-04	278	39	5	int:NSD2
Interaction	CYP4V2 interactions	SIN3A NEMF	1.99e-04	11	39	2	int:CYP4V2
Interaction	HDAC1 interactions	MKI67 NOLC1 KMT2A SIN3A ZZZ3 ERCC6 VPS4B TRPS1 NPAT	2.11e-04	1108	39	9	int:HDAC1
Interaction	PI4KB interactions	NOLC1 TCOF1 RAB5A	2.12e-04	60	39	3	int:PI4KB
Interaction	RBBP5 interactions	MKI67 KMT2A SIN3A ZZZ3 TCOF1	2.19e-04	287	39	5	int:RBBP5
Interaction	YY1 interactions	MKI67 KMT2A DIDO1 SIN3A ZZZ3 INTS12	2.20e-04	454	39	6	int:YY1
Interaction	CAVIN1 interactions	NOLC1 ERCC6 TCOF1 NNT RAB5A	2.37e-04	292	39	5	int:CAVIN1
Interaction	DNAH3 interactions	MKI67 RSL1D1	2.38e-04	12	39	2	int:DNAH3
Interaction	HCFC1 interactions	MKI67 KMT2A DIDO1 SIN3A ZZZ3	2.41e-04	293	39	5	int:HCFC1
Interaction	RNF113A interactions	MKI67 NOLC1 SIN3A TCOF1 RSL1D1 FECH TRPS1	3.22e-04	692	39	7	int:RNF113A
Interaction	BRD3 interactions	MKI67 NOLC1 KMT2A LTBP1 INTS12 FAM90A1	3.45e-04	494	39	6	int:BRD3
Interaction	RCOR1 interactions	MKI67 SIN3A ZZZ3 VPS4B TRPS1 NPAT	3.45e-04	494	39	6	int:RCOR1
Interaction	CHD4 interactions	MKI67 NOLC1 KMT2A SIN3A ERCC6 TCOF1 RSL1D1 TRPS1	3.63e-04	938	39	8	int:CHD4
Interaction	SRPK2 interactions	MKI67 NOLC1 DIDO1 OCEL1 FAM90A1 TCOF1 RSL1D1	3.99e-04	717	39	7	int:SRPK2
GeneFamily	PHD finger proteins	KMT2A DIDO1 INTS12	1.49e-04	90	21	3	88
GeneFamily	Protein disulfide isomerases	PDIA4 PDILT	2.66e-04	21	21	2	692
GeneFamily	Fibronectin type III domain containing	MYBPH CSF2RB	1.46e-02	160	21	2	555
Coexpression	PUJANA_ATM_PCC_NETWORK	MYBPH MKI67 NOLC1 DIDO1 ZZZ3 CSF2RB TCOF1 RSL1D1 VPS4B KIFC1 NPAT	2.94e-06	1394	38	11	M9585
ToppCell	E18.5-samps-Mesenchymal-Matrix_fibroblast-matrix_-_immature_4\|E18.5-samps / Age Group, Lineage, Cell class and subclass	MKI67 ERCC6 TCOF1 TXNDC2	5.06e-06	130	39	4	169d88bffd7cd813a484d809defa638ceaca4bcb
ToppCell	facs-Brain_Myeloid-Cortex-3m-Myeloid-macrophage\|Brain_Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MKI67 LTBP1 HP TRPS1	9.64e-06	153	39	4	0ef7c45cdd854c79e527006034029767f8e108b2
ToppCell	facs-Limb_Muscle-Muscle_Diaphragm-18m-Myeloid-new-cluster\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MKI67 LAMP3 HP KIFC1	1.60e-05	174	39	4	718e14d9a4264456459bec4c062c94c3a848d43a
ToppCell	droplet-Lung-18m-Hematologic-myeloid-classical_monocyte-classical_monocyte_l14\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	MKI67 CSF2RB HP TRPS1	1.60e-05	174	39	4	02ab165b064acb91f2d3f59cc5be195899d61a83
ToppCell	facs-Limb_Muscle-Muscle_Diaphragm-18m-Myeloid-macrophage\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MKI67 LAMP3 HP KIFC1	1.64e-05	175	39	4	61fdafba120fbda063d4dc05263d6f8d1dcab1e1
ToppCell	facs-Limb_Muscle-Muscle_Diaphragm-18m-Myeloid\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MKI67 LAMP3 HP KIFC1	1.64e-05	175	39	4	8de8031fdf2af187642833feb80caa64932897cf
ToppCell	PND10-Immune-Immune_Myeloid-Monocytic-Macrophage-iMON-iMON_G2M\|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	MKI67 SLX4IP OCEL1 KIFC1	1.67e-05	176	39	4	90f8bb11f339f67f08692a0c33dd420f5cda2861
ToppCell	Bac-SEP-Lymphocyte-B-Plasmablast\|Bac-SEP / Disease, Lineage and Cell Type	MKI67 PDIA4 ENAM KIFC1	2.21e-05	189	39	4	6339b6d1056e07cefb0e1b2a0e479913c5783c8a
ToppCell	10x_3'_v3-blood_(10x_3'_v3)-lymphocytic-B_lymphocytic-plasma_cell\|blood_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type	MKI67 PDIA4 ENAM KIFC1	2.30e-05	191	39	4	b23fdcd3090df9f58310b4dc8f7dc0c6d6b33226
ToppCell	mild-Myeloid-Immature_Neutrophils_2\|mild / Cohort 2 (Rhapsody WB + PBMC) with disease condition, lineage and cell classs	MKI67 B4GALNT3 HP KIFC1	2.35e-05	192	39	4	0445fdc670fa7b847dcd0a061d7736ddcf3519ba
ToppCell	Tracheal-10x5prime-Immune_Myeloid-Macrophage_alveolar-Macro_alv_dividing\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	MKI67 CSF2RB KIFC1 ZNF114	2.50e-05	195	39	4	c96755d2eb98112b703b5dbee9c88730ace7dcbf
ToppCell	Sepsis-Bac-SEP-Lymphocyte-B-Plasmablast\|Bac-SEP / Disease, condition lineage and cell class	MKI67 PDIA4 ENAM KIFC1	2.65e-05	198	39	4	614055c11d1dd2f3f2b8783ec35a8f4570cad161
ToppCell	COVID-19-COVID-19_Mild-Myeloid-immature_Neutrophil\|COVID-19_Mild / Disease, condition lineage and cell class	MKI67 CCDC168 FAM90A1 HP	2.71e-05	199	39	4	e222b90caf45904d8f763574e7b6aac13333df92
ToppCell	Brain_organoid-organoid_Tanaka_cellReport-5w-Neuronal-Intermediate\|5w / Sample Type, Dataset, Time_group, and Cell type.	KMT2A EIF4G3 MAP6 WAC	2.76e-05	200	39	4	c92e4fc0442404481fcac623d691dae6215b852d
ToppCell	saliva-Severe-critical_progression_d12-22_no-steroids-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD4_c01-LEF1\|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)	NNT PDILT KIFC1	2.86e-04	147	39	3	e99197e3c2e9d63153cc55ae62b30b8363c2267e
ToppCell	Dividing_Macrophages-Donor_02\|World / lung cells shred on cell class, cell subclass, sample id	MKI67 FAM90A1 KIFC1	2.92e-04	148	39	3	66b51aa6690bf8fbc90fa5a6f86191703e2d5046
ToppCell	10x5'-bone_marrow-Lymphocytic_B-GC_B_(I)\|bone_marrow / Manually curated celltypes from each tissue	MKI67 CCDC168 KIFC1	3.47e-04	157	39	3	d4da4057917dda066da0f2aac2621fdaf1fb943b
ToppCell	E15.5-Hematopoietic\|E15.5 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	CSF2RB HP FECH	3.47e-04	157	39	3	6315aef4b9bf673069d43a730d4e940011509ac1
ToppCell	droplet-Limb_Muscle-MUSCLE-30m-Myeloid-unknown\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MKI67 HP KIFC1	3.54e-04	158	39	3	1e7bf5f51a6582026b844095fc11434430a83dab
ToppCell	CV-Mild-3\|Mild / Virus stimulation, Condition and Cluster	TCOF1 KIFC1 FECH	4.09e-04	166	39	3	5599f90fc0e15a3670b03187085eba91228390a2
ToppCell	wk_20-22-Hematologic-Myeloid-Mast\|wk_20-22 / Celltypes from embryonic and fetal-stage human lung	CCDC168 CSF2RB NMT2	4.09e-04	166	39	3	004ab6a1425d812c7ce572205875fd702d4a9659
ToppCell	droplet-Marrow-BM_(NON-STC)-30m-Myeloid\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MKI67 CSF2RB HP	4.16e-04	167	39	3	1bd27ffe381d26731b6d4cc5f29b27f1bac4473b
ToppCell	367C-Myeloid-Dendritic-pDC\|367C / Donor, Lineage, Cell class and subclass (all cells)	MYBPH ENAM CSF2RB	4.16e-04	167	39	3	650de8cd5df070639b8aa292aacead739cfdb02c
ToppCell	droplet-Trachea-3m-Hematologic-myeloid-granulocyte-granulocyte_l34\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	MKI67 CSF2RB KIFC1	4.23e-04	168	39	3	84977db9d71e59208727885320cc18d80d064380
ToppCell	(3)_DC_plasmacytoid\|World / Lung cell shreds - cell class (v4) and cell subclass (v4)	MYBPH ENAM CSF2RB	4.23e-04	168	39	3	8a913db9b2a1a4ff96fb139734a3834e6aa263f1
ToppCell	healthy_donor-Myeloid-Monocytic-Developing_Neutrophil\|healthy_donor / Disease condition, Lineage, Cell class and subclass	MKI67 HP KIFC1	4.38e-04	170	39	3	cfd7f29805b7c51666b0eaf269c36c96b8765a1a
ToppCell	367C-Myeloid-Dendritic-pDC\|Dendritic / Donor, Lineage, Cell class and subclass (all cells)	MYBPH ENAM ZNF114	4.38e-04	170	39	3	fbb7019c6fba87326702b51f6819ea1af5f3a9b7
ToppCell	droplet-Kidney-nan-24m-Lymphocytic-lymphocyte\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MKI67 HP KIFC1	4.46e-04	171	39	3	ff117bf1a0755aa7d7c3db29749a7b9b90cc0b2f
ToppCell	facs-Marrow-T_cells-18m-Myeloid-granulocytopoietic_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MKI67 HP KIFC1	4.46e-04	171	39	3	95e87987a2332fa646849fb0de785f1e0b8a07dd
ToppCell	facs-Marrow-T_cells-18m-Myeloid-granulocytopoietic_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MKI67 HP KIFC1	4.46e-04	171	39	3	36657e277aad75c4f157c1726c48e09b5836cf37
ToppCell	droplet-Marrow-BM_(NON-STC)-30m\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MKI67 HP FECH	4.53e-04	172	39	3	31c5710fd7ebb221e703545595f5ec0ee3a32bcf
ToppCell	droplet-Kidney-nan-24m-Lymphocytic-CD45\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MKI67 HP KIFC1	4.53e-04	172	39	3	95219814e37259e34be053572cc95d4639360c27
ToppCell	droplet-Marrow-BM_(NON-STC)\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MKI67 HP FECH	4.53e-04	172	39	3	6004327045f03d832fdabe6cb2f8b1b1db57789a
ToppCell	droplet-Spleen-SPLEEN-30m\|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MKI67 HP FECH	4.53e-04	172	39	3	02cc4a9fb7902c572cee37ba828749db4913ee87
ToppCell	renal_papilla_nuclei-Adult_normal_reference-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell_cycling-Cycling_Proximal_Tubule_Epithelial_Cell_low-phase\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	MKI67 ERCC6 CSF2RB	4.61e-04	173	39	3	506efcaa5afd6ed5e565c4c4def6a4505fea97c5
ToppCell	Multiple_Sclerosis-Lymphocyte-B-Plasmablast\|Multiple_Sclerosis / Disease, Lineage and Cell Type	MKI67 PDIA4 ENAM	4.69e-04	174	39	3	e8d2aa9505817aac3fe068080774d19458f07b01
ToppCell	Dividing_Macrophages-IPF_03\|World / lung cells shred on cell class, cell subclass, sample id	MKI67 CCDC168 KIFC1	4.77e-04	175	39	3	0a8bf455babb3271aa00642199fb58b0b02dc3ac
ToppCell	PND03-Endothelial-Endothelial_blood-vessel-Macrovascular_EC-VEC-VEC_G2M\|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	MKI67 CCDC168 KIFC1	4.77e-04	175	39	3	d43ae33a6256606ce848247cad32d74f21b38988
ToppCell	T_cells-Tph_and_Tfh\|T_cells / Immune cells in Rheumatoid Arthritis Joint Synovial Tissues	MAP6 FECH TRPS1	4.85e-04	176	39	3	56c055488e34605d32562571a2fee621b47c9441
ToppCell	wk_20-22-Hematologic-Meg-ery-Cycling_definitive_erythroblast\|wk_20-22 / Celltypes from embryonic and fetal-stage human lung	MKI67 KIFC1 FECH	4.85e-04	176	39	3	98814f0a67411b2f7b25dc489b2aadb77f45a853
ToppCell	PND07-Epithelial-Epithelial_Alveolar-Epithelial_Alveolar-AT2-AT2_G2M\|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	MKI67 LAMP3 KIFC1	4.93e-04	177	39	3	a68c3688f12aee22f3cb4049c4bccacbacb0fae6
ToppCell	systemic_lupus_erythematosus-treated-Lymphocytic_B-plasmablast-female\|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex	MKI67 PDIA4 ENAM	4.93e-04	177	39	3	d2c1f46913ac00bbc0bb9320d5652edc01b34179
ToppCell	systemic_lupus_erythematosus-treated-Lymphocytic_B-plasmablast\|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex	MKI67 PDIA4 ENAM	4.93e-04	177	39	3	65e090aad0ffb737ce034e25bd5b12a0b1dd9684
ToppCell	normal-na-Lymphocytic_B-plasmablast-female\|normal / PBMC cell types (v2) per disease, treatment status, and sex	MKI67 PDIA4 ENAM	5.01e-04	178	39	3	40a280c1e35963dd45d1809a3e85b568344dd1f5
ToppCell	normal-na-Lymphocytic_B-plasmablast\|normal / PBMC cell types (v2) per disease, treatment status, and sex	MKI67 PDIA4 ENAM	5.01e-04	178	39	3	4fe87c713770173336177e3488f7b4a3be54f71b
ToppCell	facs-Marrow-Granulocytes-18m-Myeloid-granulocytopoietic_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MKI67 HP KIFC1	5.01e-04	178	39	3	15a99080e9f669572ab6d82934f324e6714846c1
ToppCell	droplet-Spleen-SPLEEN-30m-Hematologic-proerythroblast\|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MKI67 CSF2RB HP	5.01e-04	178	39	3	be8af4d85b8835a85a168639c37857dcaa6b00bf
ToppCell	Healthy_donor-Plasmablast\|Healthy_donor / disease group, cell group and cell class (v2)	MKI67 ENAM KIFC1	5.01e-04	178	39	3	388b8b4fa20dcc6e9ae4b06118e20b2c20c52bde
ToppCell	facs-Marrow-Granulocytes-18m-Myeloid-granulocytopoietic_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MKI67 HP KIFC1	5.01e-04	178	39	3	200308e109abb7e6f8816a6f8cce6d56862d4098
ToppCell	Control-Developping_Plasmablast\|Control / disease group and sub_cluster of B and Plasma cells(res = 0.5)	MKI67 PDIA4 KIFC1	5.09e-04	179	39	3	9383568f78b07b8cca72ece5d15fea209aa54ea9
ToppCell	3'_v3-blood-Lymphocytic_B_plasma-Plasmablasts\|blood / Manually curated celltypes from each tissue	MKI67 PDIA4 KIFC1	5.09e-04	179	39	3	7d3bd1f9e126a4a9e0a84720a6cc0b3d235e65ee
ToppCell	5'-Adult-Appendix-Hematopoietic-Plasma_cells\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	PDIA4 ENAM CSF2RB	5.09e-04	179	39	3	ba7744b903abfc28b39a00472661f152e9ae39fd
ToppCell	CV-Healthy-2\|CV / Virus stimulation, Condition and Cluster	LAMP3 NOLC1 KIFC1	5.18e-04	180	39	3	e182e5c495dd82d4fcbf1a920086c70b064801f3
ToppCell	3'-Pediatric_IBD-SmallIntestine-Hematopoietic-B_cells-Cycling_plasma_cell\|Pediatric_IBD / Celltypes from developing, pediatric, Crohn's, & adult GI tract	MKI67 ENAM KIFC1	5.18e-04	180	39	3	ce2fc270f9d9110c2544083f61936b0b7d3b7eb3
ToppCell	HSPCs-Mono_prog.\|HSPCs / Lineage and Cell class	PDIA4 HP TRPS1	5.26e-04	181	39	3	a188f0d22426d8723ba394d94d20431afa6722a7
ToppCell	Healthy_Control-Lymphoid-T-\|Healthy_Control / Condition, Lineage, Cell class and cell subclass	MKI67 HP KIFC1	5.26e-04	181	39	3	ac1ee313910c05b1b3cb497bae14565464919c21
ToppCell	facs-Marrow-Granulocytes-3m-Myeloid-granulocytopoietic_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MKI67 HP KIFC1	5.26e-04	181	39	3	566249e04dd491e6287ad2101b7b1ab11031ed8b
ToppCell	facs-Marrow-Granulocytes-3m-Myeloid-granulocytopoietic_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MKI67 HP KIFC1	5.26e-04	181	39	3	db9528dc7cb0230e4c36cb27da69102c588c7ee9
ToppCell	facs-Marrow-B-cells-18m-Myeloid-granulocytopoietic_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MKI67 HP KIFC1	5.35e-04	182	39	3	c075756cd4bb484ede1be2bcdb9eac60eab0573a
ToppCell	facs-Limb_Muscle-Muscle_Diaphragm\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MKI67 LAMP3 HP	5.35e-04	182	39	3	81c394959414173016426961478f670cd822f8b3
ToppCell	5'-Adult-SmallIntestine-Hematopoietic-Plasma_cells\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	ENAM KMT2A CSF2RB	5.35e-04	182	39	3	a00abff41c12b71d5860c494b8c722d649fd5f36
ToppCell	facs-Limb_Muscle-Muscle_Diaphragm-18m\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MKI67 LAMP3 HP	5.35e-04	182	39	3	41a7543c8b703441ff6ac2307faffe5f798b2c41
ToppCell	5'-Adult-SmallIntestine-Hematopoietic-Plasma_cells-IgA_plasma_cell\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	ENAM KMT2A CSF2RB	5.35e-04	182	39	3	626aabfd9ac662c1d189f7c4b660482914d9e669
ToppCell	PND01-Immune-Immune_Myeloid-Monocytic-Macrophage-AM-AM_prolif\|PND01 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	MKI67 SLX4IP CSF2RB	5.35e-04	182	39	3	57f8b8d7b132f3ad6f2b1e79c3812fe938657d2c
ToppCell	facs-Marrow-B-cells-18m-Myeloid-granulocytopoietic_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MKI67 HP KIFC1	5.35e-04	182	39	3	9025178ede571e3808d4657ad4892152f336c9b4
ToppCell	3'_v3-blood-Lymphocytic_B_plasma\|blood / Manually curated celltypes from each tissue	MKI67 PDIA4 KIFC1	5.43e-04	183	39	3	2477183a290b2c45b6fa091ed76969a3826fe3d9
ToppCell	3'-Child09-12-SmallIntestine-Hematopoietic-Plasma_cells-IgA_plasma_cell\|Child09-12 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	PDIA4 ENAM CSF2RB	5.43e-04	183	39	3	c5e90577b57a86c06afdf89d4b519b3694f813f9
ToppCell	droplet-Spleen-nan-24m-Lymphocytic-immature_NKT_cell\|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MKI67 NMT2 KIFC1	5.52e-04	184	39	3	b998803180322a5ea2b567928dea531c26816c3c
ToppCell	PND10-Immune-Immune_Lymphocytic_T/NK-Lymphocytic_B-B-B_G2M\|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	MKI67 TCOF1 KIFC1	5.52e-04	184	39	3	8f40093de5bb978f046d66e8f05f333686a009a4
ToppCell	droplet-Marrow-nan-3m-Myeloid\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	EIF4G3 TCOF1 TRPS1	5.61e-04	185	39	3	7adfa929930cfa795cbfbd9f1a0b439e08aa765d
ToppCell	3'-Child04-06-SmallIntestine-Hematopoietic-Plasma_cells-IgA_plasma_cell\|Child04-06 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	MKI67 PDIA4 ENAM	5.61e-04	185	39	3	ff598af88c7f9d7224cc4ed96b1c3463ef76b550
ToppCell	PBMC_fresh-frozen-Mild-Moderate_convalescent_d36-51-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD4_c13-MKI67-CCL5_l\|Mild-Moderate_convalescent_d36-51 / Compartment, severity and other cell annotations on 10x 3' data (130k)	MKI67 MAP6 KIFC1	5.61e-04	185	39	3	a3cd0511fa7cf317c3fcb7082fa785bbf51c5cef
ToppCell	3'-Child09-12-SmallIntestine-Hematopoietic-Plasma_cells\|Child09-12 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	PDIA4 ENAM CSF2RB	5.61e-04	185	39	3	a4792d8df52d80951fb9d022c49821df52100e67
ToppCell	droplet-Spleen-SPLEEN-30m-Hematologic\|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MKI67 KIFC1 FECH	5.69e-04	186	39	3	ac6e32cf07f0f013101ca7aedae0c562857f182b
ToppCell	mild_COVID-19-Plasmablast\|mild_COVID-19 / disease group, cell group and cell class (v2)	MKI67 PDIA4 ENAM	5.69e-04	186	39	3	a639d2183b85b1be6e6da2b2e112aec5149d5bcd
ToppCell	droplet-Spleen-SPLEEN-30m-Hematologic-nan\|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MKI67 KIFC1 FECH	5.69e-04	186	39	3	7cdcf507a9a1349ed2cf62b79116367c3fc732dd
ToppCell	systemic_lupus_erythematosus-flare-Lymphocytic_B-B_plasma\|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex	MKI67 PDIA4 ENAM	5.78e-04	187	39	3	88d20f150df61ef0e3ee0c3e9895b094920c4b09
ToppCell	PBMC_fresh-frozen-Severe-critical_progression_d03-09-Hematopoietic-Megakaryocytic\|Severe-critical_progression_d03-09 / Compartment, severity and other cell annotations on 10x 3' data (130k)	MKI67 LTBP1 FECH	5.78e-04	187	39	3	69068480f6819a6c8560ecbb05deb156b4055e12
ToppCell	droplet-Marrow-nan-24m-Myeloid-macrophage\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PDIA4 NOLC1 RSL1D1	5.78e-04	187	39	3	f491ec986dd44e2dabdf4a75c3101e3b6c921872
ToppCell	B_cells-Plasma_cells_and_plasmablasts\|World / Immune cells in Kidney/Urine in Lupus Nephritis	PDIA4 ENAM CSF2RB	5.78e-04	187	39	3	9325cadd5f2c667d526696899e7aa36a98226d4b
ToppCell	PBMC_fresh-frozen-Severe-critical_progression_d03-09-Hematopoietic-Megakaryocytic-Megakaryocyte-Mega\|Severe-critical_progression_d03-09 / Compartment, severity and other cell annotations on 10x 3' data (130k)	MKI67 LTBP1 FECH	5.78e-04	187	39	3	9c8b932a15b8b50982cba4cf8db750e257eb9503
ToppCell	PND03\|World / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	CSF2RB HP RAB5A	5.78e-04	187	39	3	b3fcb36d853adfdea7172c5591de06f027e50af3
ToppCell	PBMC_fresh-frozen-Severe-critical_progression_d03-09-Hematopoietic\|Severe-critical_progression_d03-09 / Compartment, severity and other cell annotations on 10x 3' data (130k)	MKI67 LTBP1 FECH	5.78e-04	187	39	3	46e15419e80bd7180f3171a99d845b01bb635e53
ToppCell	(2)_5-FU-(2)_LEPR+_perivascular_cells_and_VE-Cad+_vascular_cells_(mixed)\|(2)_5-FU / Stress and Cell class	PDIA4 LTBP1 HP	5.78e-04	187	39	3	6bbf0f7fe203274dae8d582652f35cd3187c0065
ToppCell	systemic_lupus_erythematosus-flare-Lymphocytic_B-B_plasma-female\|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex	MKI67 PDIA4 ENAM	5.78e-04	187	39	3	158c2c003fd225ba61793fb06eece232fb063d05
ToppCell	droplet-Marrow-nan-24m-Myeloid-granulocytopoietic_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MKI67 KIFC1 FECH	5.78e-04	187	39	3	99724aa3dbdcb073ea3bfe80cc825ecae5495db8
ToppCell	droplet-Marrow-nan-24m-Myeloid-Cd4_positive_Macrophages\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PDIA4 NOLC1 RSL1D1	5.78e-04	187	39	3	96dc5dc4dbc1b33c2e66666e9027cfbf7972090b
ToppCell	PBMC_fresh-frozen-Severe-critical_progression_d03-09-Hematopoietic-Megakaryocytic-Megakaryocyte\|Severe-critical_progression_d03-09 / Compartment, severity and other cell annotations on 10x 3' data (130k)	MKI67 LTBP1 FECH	5.78e-04	187	39	3	0d17b07770e4c881a7ca53a5bd42471457d198fb
ToppCell	control-Lymphocytic-Plasmablast\|control / Cohort 2 (Rhapsody WB + PBMC) with disease condition, lineage and cell classs	MKI67 PDIA4 ENAM	5.78e-04	187	39	3	94a44b31ce9fe6fb4758769018fb746e93c8f043
ToppCell	mild_COVID-19-Plasmablast\|World / disease group, cell group and cell class (v2)	MKI67 ENAM KIFC1	5.87e-04	188	39	3	9a5ba6abdc307402301dae25db2a5f3e0d576417
ToppCell	5'-Parenchyma_lung-Immune_Lymphocytic-Lymphocytic_B-plasma_cell-Plasma_cells-Plasma_cells_L.1.7.1.0\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	MKI67 PDIA4 ENAM	5.87e-04	188	39	3	6844cebca177fdf38b21a40d606230a033717a3a
ToppCell	droplet-Marrow-nan-18m-Myeloid-Cd4_positive_Macrophages\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PDIA4 NOLC1 RSL1D1	5.87e-04	188	39	3	1ff13434dfe60c8184d5f33041e325eca41392bc
ToppCell	COVID-19-lung-Plasma_cells_PRDM1/BLIMP_int\|COVID-19 / Disease (COVID-19 only), tissue and cell type	MKI67 PDIA4 ENAM	5.87e-04	188	39	3	599195338070ac6b79bd114609d9e10cac4f1df4
ToppCell	severe_COVID-19-Plasmablast\|World / disease group, cell group and cell class (v2)	MKI67 ENAM KIFC1	5.87e-04	188	39	3	25ca19af4ac419a0f5026a6ccbd8b554b268a6f3
ToppCell	droplet-Marrow-BM-30m-Myeloid-Cd4_positive_Macrophages\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	NOLC1 TCOF1 RSL1D1	5.87e-04	188	39	3	b2472a294b25fc2f0da7f18519fdcb9ca166c6f0
ToppCell	droplet-Marrow-nan-18m-Myeloid-macrophage\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PDIA4 NOLC1 RSL1D1	5.87e-04	188	39	3	9fc3f17045606f1fe29d296326da9482db58433b
ToppCell	3'_v3-lymph-node_spleen-Myeloid_Dendritic-Cycling_Dendritic\|lymph-node_spleen / Manually curated celltypes from each tissue	MKI67 KIFC1 ZNF114	5.87e-04	188	39	3	723348a1836a074e068320cb736ce6a953e0038f
ToppCell	systemic_lupus_erythematosus-managed-Lymphocytic_B-plasmablast-female\|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex	MKI67 PDIA4 ENAM	5.87e-04	188	39	3	ecba5d06cbf3254448255a2aeefffe711f43310e
ToppCell	3'-Broncho-tracheal-Immune_Lymphocytic-Lymphocytic_T/NK-natural_killer_cell-NK_cells-NK_cells_L.1.3.2.0\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	MKI67 CCDC168 KIFC1	5.87e-04	188	39	3	319fbeca200ab998daf49fcaee0bfdb57bf7ee4b
ToppCell	droplet-Tongue-nan\|Tongue / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	WAC NEMF TRPS1	5.87e-04	188	39	3	d62cc37e86b7b186e53aeb7f421c4e5ee28f23bd
Disease	Treacher Collins syndrome (implicated_via_orthology)	NOLC1 TCOF1	2.29e-05	6	37	2	DOID:2908 (implicated_via_orthology)
Disease	Craniofacial Abnormalities	SIN3A ERCC6 TCOF1 TRPS1	4.33e-05	156	37	4	C0376634
Disease	Colorectal Carcinoma	MKI67 ZZZ3 ERCC6 TCOF1 PDILT WAC	2.20e-04	702	37	6	C0009402
Disease	Severe Congenital Microcephaly	SIN3A ERCC6	6.95e-04	31	37	2	C3853041
Disease	Microlissencephaly	SIN3A ERCC6	7.88e-04	33	37	2	C1956147
Disease	lung cancer (is_marker_for)	MKI67 ERCC6	1.10e-03	39	37	2	DOID:1324 (is_marker_for)
Disease	body surface area	DIDO1 LTBP1 B4GALNT3 PDILT TRPS1	1.18e-03	643	37	5	EFO_0022196
Disease	lean body mass	SLX4IP DIDO1 LTBP1 TRPS1	1.27e-03	379	37	4	EFO_0004995
Disease	non-high density lipoprotein cholesterol measurement	ENAM ZZZ3 B4GALNT3 HP TRPS1	1.87e-03	713	37	5	EFO_0005689
Disease	leukemia	KMT2A HP	2.18e-03	55	37	2	C0023418

Protein segments in the cluster

Peptide	Gene	Start	Entry
IPVQQPEKRKQKPSP	B4GALNT3	506	Q6L9W6
TPFGTQIPQKQEKKP	ERCC6	246	Q03468
TQPPKKAVEKQQPVE	NOLC1	306	Q14978
AIAKKLPKNEPQNPG	RAB5A	176	P20339
QPQPGPHKAKTKKIV	OCEL1	101	Q9H607
QKTQKPPQKPAPAVV	INTS12	221	Q96CB8
PVPPKSQKAQGLRNK	NPAT	986	Q14207
TPFGTQIPQKQEKKP	ERCC6	246	P0DP91
PVKNQGPVVPESVKN	MAP6	701	Q96JE9
KKTPKSPVGVQPILN	HP	321	P00738
KIQQPSKNPSVPMQK	NMT2	76	O60551
PVKKQPQKPRGGQRV	NEMF	921	O60524
KPQVEANPGPLNKDK	FAM90A1	86	Q86YD7
TGLKNQKPVPAVPVQ	KIFC1	101	Q9BW19
GKGPVFVKPKNTQPV	LTBP1	751	Q14766
QDIKKPVQQPAKQAP	LAMP3	46	Q9UQV4
NLPGSKRQPQTPKEK	MKI67	2416	P46013
QVKKPPGQAVPQVPV	CSF2RB	856	P32927
AVGKQPAPRNLVPKK	DIDO1	556	Q9BTC0
QSKQKKVAPRPSIPV	KMT2A	1341	Q03164
ETQKPNQTQSKKPPQ	ENAM	121	Q9NRM1
KVQQQKAFPGTVPIP	CCDC168	6306	Q8NDH2
AKPQVQPQKRKPKTG	FECH	56	P22830
VPTQQQPPPAKREKK	EIF4G3	126	O43432
PKNIPQGAPVKQKTV	NNT	441	Q13423
VVVVVAKPKGPPVQK	PDILT	561	Q8N807
KGPPQKAGPVAVQVK	TCOF1	586	Q13428
KPQVEANPGPLNKDK	FAM90A26	86	D6RGX4
GTVKKPQLNNKPQRP	SIN3A	406	Q96ST3
TVNLQIPFQGKPKPQ	MYBPH	191	Q13203
KPVIKSQPVPKNNKG	PDIA4	511	P13667
SQPVPKNNKGPVKVV	PDIA4	516	P13667
SQPKVSTPVVKQGPV	WAC	476	Q9BTA9
PCPKQSPRVAKTQQK	SLX4IP	281	Q5VYV7
KKAQKPVKEGQPSPA	VPS4B	81	O75351
KAPPNVKNEGPLNVV	TRPS1	1186	Q9UHF7
PQLVPIGKKTPANEK	RSL1D1	366	O76021
KKQCPPKGTIIPAQQ	SPRR4	51	Q96PI1
PIQPKLGNIPKASVK	TXNDC2	156	Q86VQ3
PIQPKLGNIPKASVK	TXNDC2	261	Q86VQ3
KPQVEANPGPLNKDK	FAM90A2P	86	Q658T7
KKRPEPVPIQKGNNN	ZZZ3	51	Q8IYH5
QGVNNVKPPAVAPEK	ZNF114	101	Q8NC26