Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	enzyme-substrate adaptor activity	PRAMEF7 PRAMEF1 PRAMEF2 ANAPC7 PRAMEF12 TUT1 PRAMEF8 PRAMEF13 PRAMEF14	1.09e-06	95	221	9	GO:0140767
GeneOntologyMolecularFunction	nuclear retinoic acid receptor binding	PRAMEF7 PRAMEF1 PRAMEF2 PRAMEF12 PRAMEF8 PRAMEF13 PRAMEF14	2.39e-06	55	221	7	GO:0042974
GeneOntologyMolecularFunction	ubiquitin-like ligase-substrate adaptor activity	PRAMEF7 PRAMEF1 PRAMEF2 PRAMEF12 PRAMEF8 PRAMEF13 PRAMEF14	3.48e-05	82	221	7	GO:1990756
GeneOntologyMolecularFunction	microfilament motor activity	MYO7B MYH7B MYO1B MYO1F MYO15A	5.92e-05	38	221	5	GO:0000146
GeneOntologyMolecularFunction	actin filament binding	MYO7B VPS16 MYH7B SYNE1 MYO1B FMNL3 MYO1F MACF1 MYO15A KLHL17	2.29e-04	227	221	10	GO:0051015
GeneOntologyMolecularFunction	cytoskeletal motor activity	KIF1A MYO7B DNAH14 MYH7B MYO1B MYO1F MYO15A	3.45e-04	118	221	7	GO:0003774
GeneOntologyMolecularFunction	alpha1-adrenergic receptor activity	ADRA1B ADRA1A	3.63e-04	3	221	2	GO:0004937
GeneOntologyMolecularFunction	transmembrane signaling receptor activity	GABRG1 IGSF6 AVPR2 GPR146 ADRA1B ADRA1A GPR142 OR6C70 SCN7A ADGRE4P OR5K2 FGFR1 TAS2R20 GPR21 OR4C16 OR4C6 GRIN2D CRHR1 OR9A1P P2RX1 OR11A1 P2RY2 OR52L2P OR5H8 TLR4 PTCH2 OR5H2 OR51G1 OR51B4	4.80e-04	1353	221	29	GO:0004888
GeneOntologyMolecularFunction	monoatomic ion channel activity	GABRG1 ANO9 ITPR2 SLC26A8 SLC9C1 CLCN1 CLCN5 SCN5A SCN7A SCN9A KCNQ3 GRIN2D P2RX1 KCNH5	6.26e-04	459	221	14	GO:0005216
GeneOntologyBiologicalProcess	blastocyst formation	PRAMEF7 PRAMEF1 PRAMEF2 RTN4 PRAMEF12 PRAMEF8 SKIL PRAMEF13 PRAMEF14	1.52e-07	78	221	9	GO:0001825
GeneOntologyBiologicalProcess	somatic stem cell population maintenance	PRAMEF7 PRAMEF1 PRAMEF2 MED12 PRAMEF12 PRAMEF8 PRAMEF13 PRAMEF14	2.15e-05	108	221	8	GO:0035019
GeneOntologyBiologicalProcess	blastocyst development	PRAMEF7 INTS1 PRAMEF1 PRAMEF2 RTN4 PRAMEF12 PRAMEF8 SKIL PRAMEF13 PRAMEF14	2.43e-05	179	221	10	GO:0001824
GeneOntologyCellularComponent	Cul2-RING ubiquitin ligase complex	PRAMEF7 PRAMEF1 PRAMEF2 PRAMEF12 PRAMEF8 PRAMEF13 PRAMEF14 ASB4	3.14e-08	47	222	8	GO:0031462
GeneOntologyCellularComponent	cullin-RING ubiquitin ligase complex	PRAMEF7 CAND1 CUL9 PRAMEF1 PRAMEF2 ANAPC7 PRAMEF12 PRAMEF8 PRAMEF13 CCNF PRAMEF14 ASB4 TNFAIP1	4.62e-07	212	222	13	GO:0031461
GeneOntologyCellularComponent	ubiquitin ligase complex	UBR1 PRAMEF7 CAND1 CUL9 PRAMEF1 PRAMEF2 PCGF6 ANAPC7 MED12 PRAMEF12 PRAMEF8 PRAMEF13 CCNF PRAMEF14 ASB4 TNFAIP1	1.23e-06	352	222	16	GO:0000151
GeneOntologyCellularComponent	early endosome	MON2 RIN3 VPS16 RCC2 TBC1D16 ZFYVE9 CLCN5 RABGAP1L VPS18 MYO1B ALS2 HPS3 ZFYVE28 P2RY2 TLR4 CD274	6.00e-05	481	222	16	GO:0005769
GeneOntologyCellularComponent	motile cilium	PRAMEF7 IFT172 PRAMEF1 PRAMEF2 DNAH14 DNAAF5 SLC26A8 SLC9C1 TAS2R20 PRAMEF12 PRAMEF8 PRAMEF13 CFAP69	1.16e-04	355	222	13	GO:0031514
GeneOntologyCellularComponent	autophagosome	AUP1 LRRK2 VPS16 SRPX VPS18 ATP13A2 WDFY3	2.84e-04	119	222	7	GO:0005776
GeneOntologyCellularComponent	myosin complex	MYO7B MYH7B MYO1B MYO1F MYO15A	4.06e-04	59	222	5	GO:0016459
GeneOntologyCellularComponent	transferase complex	PRPSAP1 UBR1 PRAMEF7 CAND1 CCNP CUL9 PRAMEF1 PRAMEF2 PCGF6 ANAPC7 MED12 OGT PRAMEF12 CCNJ PRAMEF8 PRAMEF13 CCNF PRAMEF14 ASB4 TNFAIP1 WDFY3 KRTCAP2	6.24e-04	963	222	22	GO:1990234
GeneOntologyCellularComponent	voltage-gated sodium channel complex	SCN5A SCN7A SCN9A	7.20e-04	17	222	3	GO:0001518
GeneOntologyCellularComponent	sarcolemma	SLC30A1 ADRA1B ADRA1A CLCN1 SCN5A DMD AKAP6 SSPN	9.92e-04	190	222	8	GO:0042383
MousePheno	abnormal duodenum morphology	PRAMEF7 PRAMEF1 PRAMEF2 GDNF PRAMEF12 FADS6 PRAMEF8 PRAMEF13	1.05e-06	64	171	8	MP:0003271
MousePheno	abnormal spermatogonia proliferation	PRAMEF7 PRAMEF1 PRAMEF2 PRAMEF12 PRAMEF8 PRAMEF13 PRAMEF14	1.51e-06	47	171	7	MP:0002685
MousePheno	abnormal jejunum morphology	PRAMEF7 PRAMEF1 PRAMEF2 PRAMEF12 PRAMEF8 PRAMEF13	9.68e-06	41	171	6	MP:0004002
MousePheno	increased kidney weight	PRAMEF7 LRRK2 PRAMEF1 PRAMEF2 ZZEF1 GDNF PRAMEF12 PRAMEF8 PRAMEF13 PRAMEF14	1.15e-05	145	171	10	MP:0003917
MousePheno	enlarged urinary bladder	PRAMEF7 RABGAP1 PRAMEF1 PRAMEF2 NELFA PRAMEF12 PRAMEF8 PRAMEF13 PTCH2	1.24e-05	116	171	9	MP:0011874
MousePheno	abnormal cecum morphology	PRAMEF7 PRAMEF1 PRAMEF2 PRAMEF12 FADS6 PRAMEF8 PRAMEF13 TLR4	2.83e-05	99	171	8	MP:0000494
Domain	PRAME_family	PRAMEF7 PRAMEF1 PRAMEF2 PRAMEF12 PRAMEF8 PRAMEF13	5.34e-08	19	216	6	IPR026271
Domain	-	PRAMEF7 LRRK2 PRAMEF1 PRAMEF2 LRCH1 LRRC14B TONSL SLITRK6 CARMIL2 PRAMEF12 PRAMEF8 PRAMEF13 NLRP2 TLR4 LRCH4 NLRP4	1.09e-06	321	216	16	3.80.10.10
Domain	L_dom-like	PRAMEF7 LRRK2 PRAMEF1 PRAMEF2 LRCH1 LRRC14B TONSL SLITRK6 CARMIL2 PRAMEF12 PRAMEF8 PRAMEF13 NLRP2 TLR4 LRCH4 NLRP4	1.45e-06	328	216	16	IPR032675
Domain	ARM-type_fold	MON2 CAND1 IFT172 LRRK2 INTS1 CUL9 ITPR2 DNAAF5 COPG1 SCYL3 HEATR5A FMNL3 RNPEP WDFY3 CFAP69 PPP6R3	2.23e-06	339	216	16	IPR016024
Domain	IQ	MYO7B SCN5A SCN7A SCN9A MYH7B MYO1B MYO1F MYO15A	4.38e-06	81	216	8	SM00015
Domain	IQ_motif_EF-hand-BS	MYO7B SCN5A SCN7A SCN9A MYH7B MYO1B MYO1F MYO15A	9.66e-06	90	216	8	IPR000048
Domain	Kinesin-like	KIF1A RABGAP1 RABGAP1L	2.97e-05	6	216	3	IPR022164
Domain	DUF3694	KIF1A RABGAP1 RABGAP1L	2.97e-05	6	216	3	PF12473
Domain	-	MON2 CAND1 LRRK2 CUL9 DNAAF5 MED12 COPG1 SCYL3 HEATR5A WDFY3 CFAP69	5.74e-05	222	216	11	1.25.10.10
Domain	Myosin_head_motor_dom	MYO7B MYH7B MYO1B MYO1F MYO15A	7.27e-05	38	216	5	IPR001609
Domain	MYOSIN_MOTOR	MYO7B MYH7B MYO1B MYO1F MYO15A	7.27e-05	38	216	5	PS51456
Domain	Myosin_head	MYO7B MYH7B MYO1B MYO1F MYO15A	7.27e-05	38	216	5	PF00063
Domain	MYSc	MYO7B MYH7B MYO1B MYO1F MYO15A	7.27e-05	38	216	5	SM00242
Domain	ARM-like	MON2 CAND1 LRRK2 CUL9 DNAAF5 MED12 COPG1 SCYL3 HEATR5A WDFY3 CFAP69 PPP6R3	7.57e-05	270	216	12	IPR011989
Domain	IQ	MYO7B SCN5A SCN9A MYH7B MYO1B MYO1F MYO15A	1.02e-04	93	216	7	PS50096
Domain	Na_channel_asu	SCN5A SCN7A SCN9A	1.72e-04	10	216	3	IPR001696
Domain	Na_trans_assoc	SCN5A SCN7A SCN9A	1.72e-04	10	216	3	IPR010526
Domain	Na_trans_assoc	SCN5A SCN7A SCN9A	1.72e-04	10	216	3	PF06512
Domain	Ion_trans_dom	ITPR2 SLC9C1 SCN5A SCN7A SCN9A KCNQ3 KCNH5	3.63e-04	114	216	7	IPR005821
Domain	Ion_trans	ITPR2 SLC9C1 SCN5A SCN7A SCN9A KCNQ3 KCNH5	3.63e-04	114	216	7	PF00520
Domain	LRR_6	TONSL CARMIL2 NLRP2 TLR4 NLRP4	4.29e-04	55	216	5	PF13516
Domain	SPEC	DMD AKAP6 SYNE1 MACF1	4.85e-04	32	216	4	SM00150
Domain	Spectrin/alpha-actinin	DMD AKAP6 SYNE1 MACF1	4.85e-04	32	216	4	IPR018159
Pubmed	Differences in gene expression between mouse and human for dynamically regulated genes in early embryo.	PRAMEF7 PRAMEF1 PRAMEF2 PRAMEF12 PRAMEF8 PRAMEF13 NLRP2 PRAMEF14 NLRP4	9.68e-14	28	223	9	25089626
Pubmed	Oocyte-specific gene Oog1 suppresses the expression of spermatogenesis-specific genes in oocytes.	PRAMEF7 PRAMEF1 PRAMEF2 PRAMEF12 PRAMEF8 PRAMEF13 PRAMEF14	1.22e-11	18	223	7	29731491
Pubmed	Identification of a new expanding family of genes characterized by atypical LRR domains. Localization of a cluster preferentially expressed in oocyte.	PRAMEF7 PRAMEF1 PRAMEF2 PRAMEF12 PRAMEF8 PRAMEF13 PRAMEF14	1.22e-11	18	223	7	14675769
Pubmed	The promoter of the oocyte-specific gene, Oog1, functions in both male and female meiotic germ cells in transgenic mice.	PRAMEF7 PRAMEF1 PRAMEF2 PRAMEF12 PRAMEF8 PRAMEF13 PRAMEF14	1.22e-11	18	223	7	23894331
Pubmed	Oogenesin is a novel mouse protein expressed in oocytes and early cleavage-stage embryos.	PRAMEF7 PRAMEF1 PRAMEF2 PRAMEF12 PRAMEF8 PRAMEF13 PRAMEF14	1.22e-11	18	223	7	12890732
Pubmed	Thirteen Ovary-Enriched Genes Are Individually Not Essential for Female Fertility in Mice.	PRAMEF7 PRAMEF1 PRAMEF2 PRAMEF12 PRAMEF8 PRAMEF13 NLRP2 PRAMEF14	1.31e-11	30	223	8	38786026
Pubmed	Pramel7 mediates ground-state pluripotency through proteasomal-epigenetic combined pathways.	PRAMEF7 PRAMEF1 PRAMEF2 PRAMEF12 PRAMEF8 PRAMEF13 PRAMEF14	1.91e-11	19	223	7	28604677
Pubmed	Preferentially Expressed Antigen in Melanoma (PRAME) and the PRAME Family of Leucine-Rich Repeat Proteins.	PRAMEF7 PRAMEF1 PRAMEF2 PRAMEF12 PRAMEF8 PRAMEF13 PRAMEF14	2.93e-11	20	223	7	26694250
Pubmed	Pramel7 mediates LIF/STAT3-dependent self-renewal in embryonic stem cells.	PRAMEF7 PRAMEF1 PRAMEF2 PRAMEF12 PRAMEF8 PRAMEF13 PRAMEF14	2.93e-11	20	223	7	21425410
Pubmed	Oog1, an oocyte-specific protein, interacts with Ras and Ras-signaling proteins during early embryogenesis.	PRAMEF7 PRAMEF1 PRAMEF2 PRAMEF12 PRAMEF8 PRAMEF13 PRAMEF14	2.93e-11	20	223	7	16580637
Pubmed	Sertoli cell-only phenotype and scRNA-seq define PRAMEF12 as a factor essential for spermatogenesis in mice.	PRAMEF7 PRAMEF1 PRAMEF2 PRAMEF12 PRAMEF8 PRAMEF13 PRAMEF14	6.37e-11	22	223	7	31729367
Pubmed	Oogenesis specific genes (Nobox, Oct4, Bmp15, Gdf9, Oogenesin1 and Oogenesin2) are differentially expressed during natural and gonadotropin-induced mouse follicular development.	PRAMEF7 PRAMEF1 PRAMEF2 PRAMEF12 PRAMEF8 PRAMEF13 PRAMEF14	9.11e-11	23	223	7	19480014
Pubmed	Incomplete reactivation of Oct4-related genes in mouse embryos cloned from somatic nuclei.	PRAMEF7 PRAMEF1 PRAMEF2 PRAMEF12 PRAMEF8 PRAMEF13 PRAMEF14	1.77e-10	25	223	7	12620990
Pubmed	MAGE-B4, a binding partner of PRAMEF12, is dispensable for spermatogenesis and male fertility in mice.	PRAMEF7 PRAMEF1 PRAMEF2 PRAMEF12 PRAMEF8 PRAMEF13 PRAMEF14	1.77e-10	25	223	7	37451217
Pubmed	Expression profiling in transgenic FVB/N embryonic stem cells overexpressing STAT3.	PRAMEF7 PRAMEF1 PRAMEF2 PRAMEF12 PRAMEF8 PRAMEF13 PRAMEF14	2.40e-10	26	223	7	18500982
Pubmed	Differential expression of PRAMEL1, a cancer/testis antigen, during spermatogenesis in the mouse.	PRAMEF7 PRAMEF1 PRAMEF2 PRAMEF12 PRAMEF8 PRAMEF13	7.58e-10	17	223	6	23565261
Pubmed	Mouse Pramel1 regulates spermatogonial development by inhibiting retinoic acid signaling during spermatogenesis.	PRAMEF7 PRAMEF1 PRAMEF2 PRAMEF12 PRAMEF8 PRAMEF13	7.58e-10	17	223	6	37781892
Pubmed	Pramel15 facilitates zygotic nuclear DNMT1 degradation and DNA demethylation.	PRAMEF7 PRAMEF1 PRAMEF2 PRAMEF12 PRAMEF8 PRAMEF13	1.13e-09	18	223	6	39181896
Pubmed	LSM14B is essential for oocyte meiotic maturation by regulating maternal mRNA storage and clearance.	PRAMEF7 PRAMEF1 PRAMEF2 PRAMEF12 PRAMEF8 PRAMEF13 PRAMEF14	1.19e-09	32	223	7	37889087
Pubmed	Retinoic acid receptors are required for skeletal growth, matrix homeostasis and growth plate function in postnatal mouse.	PRAMEF7 PRAMEF1 PRAMEF2 PRAMEF12 PRAMEF8 PRAMEF13 PRAMEF14	2.34e-09	35	223	7	19389355
Pubmed	Transcriptome analysis of mouse stem cells and early embryos.	MON2 PRAMEF7 HPSE2 PRAMEF1 PRAMEF2 SMYD4 ALS2 PRAMEF12 SRGAP2 PRAMEF8 PRAMEF13 DIS3 PRAMEF14 LRCH4 KLHL17	1.59e-08	363	223	15	14691545
Pubmed	Mbd3, a component of the NuRD co-repressor complex, is required for development of pluripotent cells.	PRAMEF7 PRAMEF1 PRAMEF2 PRAMEF12 PRAMEF8 PRAMEF13 PRAMEF14	1.75e-08	46	223	7	17287250
Pubmed	DUX is a non-essential synchronizer of zygotic genome activation.	PRAMEF7 PRAMEF1 PRAMEF2 PRAMEF12 PRAMEF8 PRAMEF13 PRAMEF14	3.20e-08	50	223	7	31806660
Pubmed	A dual-activity topoisomerase complex regulates mRNA translation and turnover.	MON2 RIN3 INTS1 CUL9 ZZEF1 MAPK8IP3 ITPR2 TBC1D16 SCN5A INTS11 PLA2G6 FGFR1 MED12 ANKRD16 SZT2 GEMIN5 SRGAP2 GRIN2D LARS2 ATP13A2 WDFY3 SNAPC4 PC CD276 KLHL17	5.55e-08	1105	223	25	35748872
Pubmed	An abundance of X-linked genes expressed in spermatogonia.	PRAMEF7 PRAMEF1 PRAMEF2 PRAMEF12 PRAMEF8 PRAMEF13 NLRP4	1.04e-07	59	223	7	11279525
Pubmed	Cracking the egg: molecular dynamics and evolutionary aspects of the transition from the fully grown oocyte to embryo.	PRAMEF7 PRAMEF1 PRAMEF2 PLA2G6 FHIP1A ALS2 PRAMEF12 PRAMEF8 PRAMEF13 NLRP2 PRAMEF14 LRCH4 NLRP4	2.21e-07	326	223	13	17015433
Pubmed	Prediction of the coding sequences of mouse homologues of KIAA gene: III. the complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.	TET2 DENND2A CAND1 ZZEF1 LRCH1 RCC2 TRANK1 AKAP6 SZT2 RTN4 DIS3 IVNS1ABP FMNL3 ZFYVE28 PPP6R3	1.95e-06	529	223	15	14621295
Pubmed	ZAR1 and ZAR2 are required for oocyte meiotic maturation by regulating the maternal transcriptome and mRNA translational activation.	PRAMEF7 PRAMEF1 PRAMEF2 PRAMEF12 PRAMEF8 PRAMEF13	1.99e-06	58	223	6	31598710
Pubmed	The DNA sequence and biological annotation of human chromosome 1.	PRAMEF7 PEX10 PRAMEF1 PRAMEF2 INTS11 IL19 ZDHHC18 SZT2 SCYL3 PRAMEF12 C1orf74 PRAMEF8 ATP13A2 DMBX1 SH2D5 PRAMEF14 PTCH2 MACF1 MAP3K21 KRTCAP2 KLHL17	3.56e-06	1031	223	21	16710414
Pubmed	Functional proteomics establishes the interaction of SIRT7 with chromatin remodeling complexes and expands its role in regulation of RNA polymerase I transcription.	KIF1A INTS1 CUL9 RCC2 MED12 COPG1 NUMA1 GEMIN5 MYO1B DDX51 PRPF8 DIS3 RNPEP MACF1 NNT PPP6R3	5.68e-06	653	223	16	22586326
Pubmed	Postural changes in blood pressure associated with interactions between candidate genes for chronic respiratory diseases and exposure to particulate matter.	ITPR2 CRHR1 TLR4 ELANE	7.35e-06	20	223	4	19590686
Pubmed	Construction of long-transcript enriched cDNA libraries from submicrogram amounts of total RNAs by a universal PCR amplification method.	PRAMEF7 ANO9 PRAMEF1 PRAMEF2 AKAP6 SOST OGT GEMIN5 ALS2 PRAMEF12 SRGAP2 PRAMEF8 PRAMEF13 DIS3 SSPN PRAMEF14 TLR4 ITPRIP MACF1 SLC35F2 NLRP4	7.64e-06	1084	223	21	11544199
Pubmed	USP7 represses lineage differentiation genes in mouse embryonic stem cells by both catalytic and noncatalytic activities.	TET2 PRAMEF7 LRRK2 HPSE2 PRAMEF1 PRAMEF2 CLCN5 KLHL34 WNK3 PRAMEF12 PRAMEF8 PRAMEF13 PRAMEF14 MYO1F TMEM35A NNT	8.43e-06	674	223	16	37196079
Pubmed	CLEC16A interacts with retromer and TRIM27, and its loss impairs endosomal trafficking and neurodevelopment.	MON2 PRPSAP1 CAND1 AUP1 GCDH DNAAF5 PARP4 OGT SZT2 FPGS MYO1B RFC3 DIS3 PC PPP6R3	9.94e-06	606	223	15	36538041
Pubmed	Sequencing analysis of forty-eight human image cDNA clones similar to Drosophila mutant protein.	PRUNE1 TLR4 KCNH5	1.42e-05	8	223	3	10524757
Pubmed	A genome-wide in situ hybridization map of RNA-binding proteins reveals anatomically restricted expression in the developing mouse brain.	PRAMEF7 MRPL44 PRAMEF1 PRAMEF2 PRAMEF12 TUT1 PRAMEF8 PRPF8 PRAMEF13 RNPEP PRAMEF14	1.68e-05	347	223	11	16033648
Pubmed	A multi-factor trafficking site on the spliceosome remodeling enzyme BRR2 recruits C9ORF78 to regulate alternative splicing.	MON2 MRPL44 VPS16 CEP120 ANAPC7 COPG1 RTN4 NUMA1 MYO1B DDX51 PRPF8 RNPEP NNT PPP6R3	1.77e-05	560	223	14	35241646
Pubmed	Deterministic and stochastic allele specific gene expression in single mouse blastomeres.	PRAMEF7 PRAMEF1 PRAMEF2 FGFR1 PRAMEF12 PRAMEF8 PRAMEF13 PRAMEF14 FRZB PTCH2 SLC35F2 NLRP4	2.14e-05	424	223	12	21731673
Pubmed	USP7 targets XIAP for cancer progression: Establishment of a p53-independent therapeutic avenue for glioma.	MYO7B RCC2 DMD SYNE1 NUMA1 MYO1B PRPF8 MACF1 PC	2.22e-05	234	223	9	36243803
Pubmed	E3 ubiquitin ligase RNF123 targets lamin B1 and lamin-binding proteins.	KIF1A TTC21A INTS1 ZZEF1 DNAH14 ITPR2 PARP4 ADRA1A R3HCC1L COPG1 IGDCC3 PRPF8 IVNS1ABP ZFYVE28 FRY TNFAIP1	2.47e-05	736	223	16	29676528
Pubmed	SARS-CoV-2 Nsp6 damages Drosophila heart and mouse cardiomyocytes through MGA/MAX complex-mediated increased glycolysis.	MON2 CAND1 AUP1 DARS1 ZZEF1 DNAAF5 PCGF6 OGT COPG1 RTN4 GEMIN5 RFC3 PRPF8 IVNS1ABP PPP6R3	2.54e-05	657	223	15	36180527
Pubmed	C5orf51 is a component of the MON1-CCZ1 complex and controls RAB7A localization and stability during mitophagy.	MON2 KIF1A AUP1 RABGAP1 VPS16 ITPR2 ZFYVE9 EIF2AK3 VPS18 RTN4 SCYL3 HPS3 LRCH4	2.56e-05	504	223	13	34432599
Pubmed	Large-scale analysis of ion channel gene expression in the mouse heart during perinatal development.	CLCN1 CLCN5 SCN5A SCN7A SCN9A KCNQ3 P2RX1	3.38e-05	139	223	7	16985003
Pubmed	An alpha1A-adrenergic-extracellular signal-regulated kinase survival signaling pathway in cardiac myocytes.	ADRA1B ADRA1A	4.09e-05	2	223	2	17283256
Pubmed	Sarcospan reduces dystrophic pathology: stabilization of the utrophin-glycoprotein complex.	DMD SSPN	4.09e-05	2	223	2	18981229
Pubmed	Soluble B7-H3 promotes the invasion and metastasis of pancreatic carcinoma cells through the TLR4/NF-κB pathway.	TLR4 CD276	4.09e-05	2	223	2	27273624
Pubmed	Combined Gemcitabine and Immune-Checkpoint Inhibition Conquers Anti-PD-L1 Resistance in Low-Immunogenic Mismatch Repair-Deficient Tumors.	MLH1 CD274	4.09e-05	2	223	2	34206051
Pubmed	Upregulated PD-L1 delays human neutrophil apoptosis and promotes lung injury in an experimental mouse model of sepsis.	CD274 ELANE	4.09e-05	2	223	2	34473230
Pubmed	TLR4 signaling induces B7-H1 expression through MAPK pathways in bladder cancer cells.	TLR4 CD274	4.09e-05	2	223	2	18608206
Pubmed	Mylk3 null C57BL/6N mice develop cardiomyopathy, whereas Nnt null C57BL/6J mice do not.	MYLK3 NNT	4.09e-05	2	223	2	32213617
Pubmed	MLK4 has negative effect on TLR4 signaling.	TLR4 MAP3K21	4.09e-05	2	223	2	21602844
Pubmed	PD-L1 expression in colorectal cancer and its relationship with TLR-4 expression.	TLR4 CD274	4.09e-05	2	223	2	32862585
Pubmed	Nuclear alpha1-adrenergic receptors signal activated ERK localization to caveolae in adult cardiac myocytes.	ADRA1B ADRA1A	4.09e-05	2	223	2	18802028
Pubmed	Immunohistological analyses of neutral glycosphingolipids and gangliosides in normal mouse skeletal muscle and in mice with neuromuscular diseases.	CLCN1 DMD	4.09e-05	2	223	2	8595265
Pubmed	ATP-induced vasodilation and purinergic receptors in the human leg: roles of nitric oxide, prostaglandins, and adenosine.	P2RX1 P2RY2	4.09e-05	2	223	2	19118095
Pubmed	Alpha1-adrenergic receptors prevent a maladaptive cardiac response to pressure overload.	ADRA1B ADRA1A	4.09e-05	2	223	2	16585965
Pubmed	Oligomerization of the alpha 1a- and alpha 1b-adrenergic receptor subtypes. Potential implications in receptor internalization.	ADRA1B ADRA1A	4.09e-05	2	223	2	12888550
Pubmed	The cellular factors Vps18 and Mon2 are required for efficient production of infectious HIV-1 particles.	MON2 VPS18	4.09e-05	2	223	2	21450827
Pubmed	Kinetic Analysis of Membrane Potential Dye Response to NaV1.7 Channel Activation Identifies Antagonists with Pharmacological Selectivity against NaV1.5.	SCN5A SCN9A	4.09e-05	2	223	2	26861708
Pubmed	High levels of sarcospan are well tolerated and act as a sarcolemmal stabilizer to address skeletal muscle and pulmonary dysfunction in DMD.	DMD SSPN	4.09e-05	2	223	2	27798107
Pubmed	Loss of sarcospan exacerbates pathology in mdx mice, but does not affect utrophin amelioration of disease.	DMD SSPN	4.09e-05	2	223	2	33432327
Pubmed	TLR4-induced B7-H1 on keratinocytes negatively regulates CD4+ T cells and CD8+ T cells responses in oral lichen planus.	TLR4 CD274	4.09e-05	2	223	2	27762043
Pubmed	Sarcospan Regulates Cardiac Isoproterenol Response and Prevents Duchenne Muscular Dystrophy-Associated Cardiomyopathy.	DMD SSPN	4.09e-05	2	223	2	26702077
Pubmed	PD-L1 Expression in Mismatch Repair-deficient Endometrial Carcinomas, Including Lynch Syndrome-associated and MLH1 Promoter Hypermethylated Tumors.	MLH1 CD274	4.09e-05	2	223	2	27984238
Pubmed	{alpha}1-Adrenergic receptor subtypes in nonfailing and failing human myocardium.	ADRA1B ADRA1A	4.09e-05	2	223	2	19919991
Pubmed	Membrane recruitment of endogenous LRRK2 precedes its potent regulation of autophagy.	LRRK2 TLR4	4.09e-05	2	223	2	24682598
Pubmed	Myo1b Promotes Premature Endothelial Senescence and Dysfunction via Suppressing Autophagy: Implications for Vascular Aging.	LRRK2 MYO1B	4.09e-05	2	223	2	36654782
Pubmed	Fibroblast growth factor receptor 1 activation in mammary tumor cells promotes macrophage recruitment in a CX3CL1-dependent manner.	FGFR1 CX3CL1	4.09e-05	2	223	2	23029290
Pubmed	Differences in the signaling pathways of α(1A)- and α(1B)-adrenoceptors are related to different endosomal targeting.	ADRA1B ADRA1A	4.09e-05	2	223	2	23717684
Pubmed	Myotonic ADR-MDX mutant mice show less severe muscular dystrophy than MDX mice.	CLCN1 DMD	4.09e-05	2	223	2	10093060
Pubmed	Mutual interference of myotonia and muscular dystrophy in the mouse: a study on ADR-MDX double mutants.	CLCN1 DMD	4.09e-05	2	223	2	10093061
Pubmed	Abnormal myocardial contraction in alpha(1A)- and alpha(1B)-adrenoceptor double-knockout mice.	ADRA1B ADRA1A	4.09e-05	2	223	2	14519431
Pubmed	Neutrophils activate macrophages for intracellular killing of Leishmania major through recruitment of TLR4 by neutrophil elastase.	TLR4 ELANE	4.09e-05	2	223	2	17785837
Pubmed	Male contraception via simultaneous knockout of α1A-adrenoceptors and P2X1-purinoceptors in mice.	ADRA1A P2RX1	4.09e-05	2	223	2	24297884
Pubmed	B7-H1 and B7-H3 are independent predictors of poor prognosis in patients with non-small cell lung cancer.	CD274 CD276	4.09e-05	2	223	2	25609202
Pubmed	Activation of the unfolded protein response is associated with impaired granulopoiesis in transgenic mice expressing mutant Elane.	EIF2AK3 ELANE	4.09e-05	2	223	2	21285438
Pubmed	Dystrophic mdx mouse myoblasts exhibit elevated ATP/UTP-evoked metabotropic purinergic responses and alterations in calcium signalling.	DMD P2RY2	4.09e-05	2	223	2	30684640
Pubmed	PD-L1 Expression in Mismatch Repair-deficient Endometrial Carcinoma and Tumor-associated Immune Cells: Differences Between MLH1 Methylated and Nonmethylated Subgroups.	MLH1 CD274	4.09e-05	2	223	2	33332859
Pubmed	TLR4 is a regulator of trained immunity in a murine model of Duchenne muscular dystrophy.	DMD TLR4	4.09e-05	2	223	2	35169163
Pubmed	Disrupted mechanical stability of the dystrophin-glycoprotein complex causes severe muscular dystrophy in sarcospan transgenic mice.	DMD SSPN	4.09e-05	2	223	2	17311848
Pubmed	Myosin-7b Promotes Distal Tip Localization of the Intermicrovillar Adhesion Complex.	MYO7B MYH7B	4.09e-05	2	223	2	27666969
Pubmed	B-cell tumor development in Tet2-deficient mice.	TET2 CD19	4.09e-05	2	223	2	29581109
Pubmed	The immune checkpoint B7-H3 (CD276) regulates adipocyte progenitor metabolism and obesity development.	CD274 CD276	4.09e-05	2	223	2	35476450
Pubmed	Attenuated purinergic receptor function in patients with type 2 diabetes.	P2RX1 P2RY2	4.09e-05	2	223	2	19808895
Pubmed	alpha(1A)- and alpha(1B)-adrenergic receptors differentially modulate antidepressant-like behavior in the mouse.	ADRA1B ADRA1A	4.09e-05	2	223	2	19540213
Pubmed	The alpha(1A/C)- and alpha(1B)-adrenergic receptors are required for physiological cardiac hypertrophy in the double-knockout mouse.	ADRA1B ADRA1A	4.09e-05	2	223	2	12782680
Pubmed	Nuclear localization drives α1-adrenergic receptor oligomerization and signaling in cardiac myocytes.	ADRA1B ADRA1A	4.09e-05	2	223	2	22120526
Pubmed	Neutrophil elastase modulates cytokine expression: contribution to host defense against Pseudomonas aeruginosa-induced pneumonia.	TLR4 ELANE	4.09e-05	2	223	2	22927440
Pubmed	Neutrophil elastase promotes neointimal hyperplasia by targeting toll-like receptor 4 (TLR4)-NF-κB signalling.	TLR4 ELANE	4.09e-05	2	223	2	34076894
Pubmed	Association of T-cell co-regulatory protein expression with clinical outcomes following radical cystectomy for urothelial carcinoma of the bladder.	CD274 CD276	4.09e-05	2	223	2	24140000
Pubmed	[Distribution and significance of α1-adrenoceptor subtypes in patients with chronic prostatitis in prostate, bladder detrusor and posterior urethral tissue].	ADRA1B ADRA1A	4.09e-05	2	223	2	21223784
Pubmed	The TLR4/ERK/PD‑L1 axis may contribute to NSCLC initiation.	TLR4 CD274	4.09e-05	2	223	2	32468028
Pubmed	PD-L1 maintains neutrophil extracellular traps release by inhibiting neutrophil autophagy in endotoxin-induced lung injury.	CD274 ELANE	4.09e-05	2	223	2	36016930
Pubmed	A cold-stress-inducible PERK/OGT axis controls TOM70-assisted mitochondrial protein import and cristae formation.	EIF2AK3 OGT	4.09e-05	2	223	2	33592173
Pubmed	Toll-like receptor 4 ablation in mdx mice reveals innate immunity as a therapeutic target in Duchenne muscular dystrophy.	DMD TLR4	4.09e-05	2	223	2	25552658
Pubmed	Prediction of the coding sequences of unidentified human genes. XVIII. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro.	TET2 WNK3 KNL1 ALS2 ZFYVE28 PPP6R3	4.96e-05	101	223	6	10997877
Pubmed	Gain of Additional BIRC3 Protein Functions through 3'-UTR-Mediated Protein Complex Formation.	CAND1 KIF1A AUP1 MRPL44 DARS1 RCC2 INTS11 ANAPC7 MARS2 COPG1 SYNE1 RTN4 NUMA1 GEMIN5 MYO1B RFC3 PRPF8 DIS3 GSPT1 IVNS1ABP RNPEP PC NNT	4.99e-05	1425	223	23	30948266
Pubmed	A high-density association screen of 155 ion transport genes for involvement with common migraine.	SCN5A SCN9A KCNQ3	5.48e-05	12	223	3	18676988
Pubmed	Proteomic profiling of VCP substrates links VCP to K6-linked ubiquitylation and c-Myc function.	UBR1 CAND1 AUP1 DARS1 VPS16 PCGF6 INTS11 MLH1 MED12 DSC3 COPG1 NUMA1 GEMIN5 MYO1B DDX51 SRBD1 RFC3 PRPF8 DIS3 GSPT1 MACF1 WDFY3	6.58e-05	1353	223	22	29467282
Pubmed	Defining the membrane proteome of NK cells.	CAND1 AUP1 INTS1 DARS1 PEX11B CCDC88B ITPR2 PARP4 CLCN5 MLH1 EIF2AK3 MED12 CARMIL2 GEMIN5 DDX51 PRPF8 DIS3 LRP10 ITPRIP NNT	7.13e-05	1168	223	20	19946888
Cytoband	1p36.21	PRAMEF7 PRAMEF1 PRAMEF2 PRAMEF12 PRAMEF8 PRAMEF13 PRAMEF14	2.55e-08	63	223	7	1p36.21
Cytoband	Ensembl 112 genes in cytogenetic band chr1p36	PRAMEF7 ANKRD65 PEX10 PRAMEF1 PRAMEF2 RCC2 INTS11 ZDHHC18 PRAMEF12 PRAMEF8 PRAMEF13 ATP13A2 SH2D5 PRAMEF14 KLHL17	1.48e-06	681	223	15	chr1p36
GeneFamily	PRAME family	PRAMEF7 PRAMEF1 PRAMEF2 PRAMEF12 PRAMEF8 PRAMEF13 PRAMEF14	1.14e-09	24	160	7	686
GeneFamily	Ankyrin repeat domain containing	ANKRD65 ANKRD18B TRANK1 TONSL PLA2G6 ANKRD16 ANKRD10 ANKRD44 ASB4	3.11e-04	242	160	9	403
GeneFamily	Parkinson disease associated genes	LRRK2 PLA2G6 ATP13A2	3.50e-04	16	160	3	672
GeneFamily	Protein phosphatase 6 regulatory subunits	ANKRD44 PPP6R3	1.14e-03	6	160	2	699
GeneFamily	Myosins, class I	MYO1B MYO1F	2.10e-03	8	160	2	1097
GeneFamily	Zinc fingers FYVE-type\|Pleckstrin homology domain containing\|Rho guanine nucleotide exchange factors	ZFYVE9 ZFYVE28 WDFY3	2.55e-03	31	160	3	81
GeneFamily	Sodium voltage-gated channel alpha subunits	SCN5A SCN9A	2.69e-03	9	160	2	1203
GeneFamily	Adrenoceptors	ADRA1B ADRA1A	2.69e-03	9	160	2	169
GeneFamily	Chloride voltage-gated channels	CLCN1 CLCN5	3.34e-03	10	160	2	302
GeneFamily	VPS9 domain containing	RIN3 ALS2	3.34e-03	10	160	2	928
GeneFamily	Tetratricopeptide repeat domain containing\|Bardet-Biedl syndrome associated\|BBSome	TTC21A TTC8 TRANK1 ANAPC7 OGT	3.58e-03	115	160	5	769
Coexpression	KINNEY_DNMT1_METHYLATION_TARGETS	PRAMEF7 PRAMEF1 PRAMEF2 PRAMEF12 PRAMEF8 PRAMEF13	3.81e-07	34	222	6	MM955
Coexpression	KOHOUTEK_CCNT2_TARGETS	PRAMEF7 PRAMEF1 PRAMEF2 PRAMEF12 PRAMEF8 PRAMEF13 PRAMEF14 MYO1F	4.41e-07	81	222	8	MM938
Coexpression	MEISSNER_BRAIN_HCP_WITH_H3_UNMETHYLATED	PRAMEF7 PAPOLB PRAMEF1 PRAMEF2 PRAMEF12 PRAMEF8 PRAMEF13	5.25e-07	57	222	7	MM1262
Coexpression	GOBERT_OLIGODENDROCYTE_DIFFERENTIATION_DN	MON2 TET2 PRAMEF7 CTSF PRAMEF1 PRAMEF2 SLC30A1 MAPK8IP3 ITPR2 PRUNE1 GPR180 TBC1D16 RABGAP1L LMF1 OGT SYNE1 RTN4 PRAMEF12 PRAMEF8 SKIL PRAMEF13 ATP13A2 SGK2 ANKRD44 EEF1AKMT2 TMEM35A	3.63e-06	1124	222	26	MM1070
Coexpression	MIKKELSEN_NPC_ICP_WITH_H3K4ME3	GABRG1 PRAMEF7 GCDH PRAMEF1 PRAMEF2 CLCN5 LOXL3 SLITRK6 PRAMEF12 TUT1 PRAMEF8 PRAMEF13 SSPN FAM111A CD274 TMEM35A	5.87e-06	497	222	16	MM863
Coexpression	GSE7509_UNSTIM_VS_FCGRIIB_STIM_MONOCYTE_DN	TET2 MAP3K4 PLA2G6 OGT SRGAP2 IVNS1ABP FRY MACF1 SNAPC4	1.28e-05	166	222	9	M6826
Coexpression	DESCARTES_ORGANOGENESIS_SCHWANN_CELL_PRECURSOR	PRAMEF7 PRAMEF1 PRAMEF2 SLITRK6 PRAMEF12 PRAMEF8 PRAMEF13	2.05e-05	98	222	7	MM3656
Coexpression	MORI_SMALL_PRE_BII_LYMPHOCYTE_UP	PRAMEF7 PRAMEF1 PRAMEF2 PRAMEF12 PRAMEF8 PRAMEF13 PRAMEF14	2.05e-05	98	222	7	MM592
Coexpression	HUANG_GATA2_TARGETS_DN	PRAMEF7 PRAMEF1 PRAMEF2 PRAMEF12 PRAMEF8 PRAMEF13 PRAMEF14	2.05e-05	98	222	7	MM942
Coexpression	FRANCO_BLOOD_SANOFI_PASTEUR_SA_INACTIVATED_INFLUENZA_VACCINE_CORRELATED_WITH_ANTIBODY_RESPONSE_AGE_18_40YO_14DY_POSITIVE	MLH1 CARMIL2 ANKRD10 CD19	4.66e-05	24	222	4	M40940
Coexpression	GSE19888_ADENOSINE_A3R_ACT_VS_TCELL_MEMBRANES_ACT_AND_A3R_INH_PRETREAT_IN_MAST_CELL_DN	ANO9 MAP3K4 ITPR2 RALBP1 ANKRD16 RTN4 IVNS1ABP SNAPC4 MAST3	5.33e-05	199	222	9	M7319
ToppCell	severe-HLA-DR+_CD83+_Monocyte\|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class	TET2 IGSF6 GLT1D1 LRRK2 SLC26A8 SRGAP2 P2RX1 TLR4 MYO1F WDFY3	6.31e-08	198	222	10	d5e525d2f2226d06a3fb985ce3a33555ff4b2e7b
ToppCell	10x_3'_v3-spleen_(10x_3'_v3)-myeloid-myeloid_granulocytic\|spleen_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type	IGSF6 GLT1D1 LRRK2 ZDHHC18 IVNS1ABP LRP10 MYO1F ITPRIP WDFY3	7.36e-07	199	222	9	119807ea333d1dc7743c6b9f03a2c63e09e19541
ToppCell	10x_3'_v3-spleen_(10x_3'_v3)-myeloid-myeloid_granulocytic-neutrophil\|spleen_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type	IGSF6 GLT1D1 LRRK2 ZDHHC18 IVNS1ABP LRP10 MYO1F ITPRIP WDFY3	7.36e-07	199	222	9	691e04871cd6cac0ea5fca1b7fd6421df9315db6
ToppCell	E16.5-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_airway-SCMF-SCMF_mature\|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	DNAAF5 SMYD4 CLCN5 LOXL3 NELFA SYNE1 PRAMEF8 SKIL	2.83e-06	175	222	8	1d8aab491dcc27ea5dbfb6462d18ee280b21a05e
ToppCell	E16.5-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_airway-SCMF\|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	DNAAF5 SMYD4 CLCN5 LOXL3 NELFA SYNE1 PRAMEF8 SKIL	2.83e-06	175	222	8	427a7ee92fe16a90625946492062d37aa0f7235b
ToppCell	facs-Lung-18m-Mesenchymal-fibroblast-adventitial_fibroblast-adventitial_fibroblast_l25-31\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	KIF1A ADRA1B SRPX LOXL3 ATP23 PTCH2 TMEM35A CD276	4.63e-06	187	222	8	fa8f221b4c2df61eadaa9c77e4cf45848b00330b
ToppCell	Control-Myeloid-ncMonocyte\|Control / Disease state, Lineage and Cell class	TET2 RIN3 LRRK2 SRGAP2 HPS3 P2RX1 P2RY2 MYO1F	6.30e-06	195	222	8	fcb05948e7480dc53f06f3fc9b9c3fc129874edd
ToppCell	Fetal_brain-organoid_Tanaka_cellReport-GW09-OPC_related-Oligodendrocyte/OPC\|GW09 / Sample Type, Dataset, Time_group, and Cell type.	MRPL44 SLC38A5 DSC3 ZBTB9 MYO1B TNFAIP1	6.34e-06	91	222	6	ed4a48e5e5f5d8aadbc7b1b8d84a5f6363a08b85
ToppCell	Fetal_brain-organoid_Tanaka_cellReport-GW09-OPC_related\|GW09 / Sample Type, Dataset, Time_group, and Cell type.	MRPL44 SLC38A5 DSC3 ZBTB9 MYO1B TNFAIP1	6.34e-06	91	222	6	25197fde8b9bdaf1e28add695d13aff3ff52d86e
ToppCell	P28-Mesenchymal-mesenchymal_fibroblast-mesenchymal_progenitor_cell\|P28 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	SLC38A5 ADRA1A IGDCC3 SH2D5 MYO1F TMEM35A CRB2	1.24e-05	154	222	7	44d4d99b08216c0901e3bc32743fa0a8b85b5149
ToppCell	10x_3'_v2v3-Neoplastic-Stem-like-NPC-like-NPC-like_OPC-D\|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	DNAH14 SLC9C1 KLHL34 CCN3 DOC2B MYH7B CRB2	1.35e-05	156	222	7	27590a4d2b419644966f0037c67c761fc275e0aa
ToppCell	Globus_pallidus-Neuronal-Excitatory\|Globus_pallidus / BrainAtlas - Mouse McCarroll V32	GLT1D1 LRRK2 KLHL34 DOC2B SH2D5 ZFYVE28 KCNH5	1.59e-05	160	222	7	f843287ed57d2d5a3b3f6dfb03b6934e330e6645
ToppCell	wk_20-22-Hematologic-Myeloid-GMP\|wk_20-22 / Celltypes from embryonic and fetal-stage human lung	RCC2 DNAH14 DNAAF5 CLCN1 KNL1 P2RX1 ELANE	2.02e-05	166	222	7	d96e88e73a40205f32cebd7e54ca1ff09ee1e7e8
ToppCell	TCGA-Ovary-Primary_Tumor-Ovarian_Carcinoma-Serous_Cystadenocarcinoma-5\|TCGA-Ovary / Sample_Type by Project: Shred V9	IFT172 TTC21A ZNF589 SZT2 NUMA1 MAP3K21 CFAP69	2.02e-05	166	222	7	32d2eaf8a5d03881bf74d680825af2d5110b082d
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Immune-Lymphocytic_B\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	CCDC88B EIF2AK3 CARMIL2 ANKRD44 SSPN P2RX1 CD19	2.64e-05	173	222	7	62ba49c1c16760a8c6cde0cc44e068f94386946a
ToppCell	Control-Lymphoid_T/NK-NK_activated\|Control / Disease group, lineage and cell class	AVPR2 ADRA1A TRANK1 SYNE1 IGDCC3 MACF1	2.94e-05	119	222	6	a258d91ac90d4174b6f203d7f96ba6e57c6003e7
ToppCell	TCGA-Brain-Primary_Tumor-Low_Grade_Glioma\|TCGA-Brain / Sample_Type by Project: Shred V9	KIF1A RABGAP1 AKAP6 SYNE1 NUMA1 WDFY3 PC	3.05e-05	177	222	7	e8ab340b20cd41554c3841fe980e078e878af35f
ToppCell	ILEUM-inflamed-(9)_Neuro_cell\|inflamed / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)	GDNF SCN7A SCN9A SLITRK6 CCN3 ASB4 WDR86	3.16e-05	178	222	7	611504b0a9e6318b18fba83787b03f9245c82252
ToppCell	ILEUM-inflamed-(9)_Enteric_neurons\|inflamed / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)	GDNF SCN7A SCN9A SLITRK6 CCN3 ASB4 WDR86	3.16e-05	178	222	7	d9142151819afb0dc22bfb32a9c9dba5f553067d
ToppCell	droplet-Heart-HEART-1m-Mesenchymal-coronary_vascular_endothelial_cell\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	AUP1 GPR146 TONSL DDX51 SRGAP2 SRBD1 ATP13A2	3.28e-05	179	222	7	dd94ebe69ade6f51b94058abe066216f0de9feda
ToppCell	kidney_cells-Hypertensive_with+without-CKD-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell-Distal_Convoluted_Tubule_Cell_Type_2\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	GABRG1 SCN7A OGT MYO1B IVNS1ABP SLC35F2 NNT	3.77e-05	183	222	7	2f0ee40e69ad1259e56e8ee4b352736900eb8901
ToppCell	NS-moderate-d_07-13-Myeloid-Neutrophil\|d_07-13 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	IGSF6 GLT1D1 LRRK2 IVNS1ABP OSM TLR4 MYO1F	3.91e-05	184	222	7	4c7d05f1a4556b13cedbaaf88d67ac32d09b109b
ToppCell	LV-15._Ventricular_Cardiomyocyte_III\|LV / Chamber and Cluster_Paper	RABGAP1L OR5K2 DMD ACSS3 AKAP6 MYH7B FRY	3.91e-05	184	222	7	ab7a1620c14a9d9b6be1b47c559931e345e9eef8
ToppCell	TCGA-Thryoid-Primary_Tumor-Thyroid_Papillary_Carcinoma-Classical-4\|TCGA-Thryoid / Sample_Type by Project: Shred V9	CAND1 MBTPS2 KCNQ3 DMBX1 SH2D5 P2RY2 SLC35F2	3.91e-05	184	222	7	d9659d1e4465fec68f48a22edef443f354f6c7cf
ToppCell	COVID-19-Heart-CM_2\|COVID-19 / Disease (COVID-19 only), tissue and cell type	ADRA1A MYLK3 SCN5A DMD AKAP6 MYH7B FRY	4.04e-05	185	222	7	549eeb521c3985bff396ea0f202db21822efa51f
ToppCell	LV-15._Ventricular_Cardiomyocyte_III\|World / Chamber and Cluster_Paper	RABGAP1L OR5K2 DMD ACSS3 AKAP6 MYH7B FRY	4.04e-05	185	222	7	6baccb26f999145e51b91d94315bf8d4655bef31
ToppCell	TCGA-Pancreas-Primary_Tumor-Pancreatic_Adenocarcinoma-Ductal_Adenocarcinoma-1\|TCGA-Pancreas / Sample_Type by Project: Shred V9	UBR1 RABGAP1 LRCH1 PARP4 TRANK1 HEATR5A ARHGAP6	4.18e-05	186	222	7	03db813598b67b1e08f759758a1c2023396921fa
ToppCell	droplet-Lung-18m-Mesenchymal-myofibroblast-tracheobronchial_smooth_muscle_cell-smooth_muscle_cell_of_trachea_l39\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	PAPOLB HPSE2 DMD AKAP6 SOST PRAMEF12 P2RX1	4.33e-05	187	222	7	218c9b4f28499389c43005d9626af2ac01066027
ToppCell	droplet-Lung-18m-Mesenchymal-myofibroblast-tracheobronchial_smooth_muscle_cell\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	PAPOLB HPSE2 DMD AKAP6 SOST PRAMEF12 P2RX1	4.33e-05	187	222	7	c7ac4b328efc2ebb72f71154661914193ff402ca
ToppCell	droplet-Lung-nan-18m-Mesenchymal-Airway_Smooth_Muscle\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PAPOLB HPSE2 DMD AKAP6 SOST PRAMEF12 P2RX1	4.48e-05	188	222	7	61f010c165826b434ca3d27553d4c9e13d2c0c51
ToppCell	droplet-Lung-nan-18m-Mesenchymal-bronchial_smooth_muscle_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PAPOLB HPSE2 DMD AKAP6 SOST PRAMEF12 P2RX1	4.48e-05	188	222	7	7553ef7de3575af4cf34704b405b551c1af8eb83
ToppCell	5'-Adult-Distal_Rectal-Mesenchymal-fibroblastic-Stromal_3_(C7+)\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	CTSF SCN7A FGFR1 SRPX WNK3 ACSS3 ELANE	4.63e-05	189	222	7	f7d57723b8fb0f1e1485f51e3eff93ec0f39761e
ToppCell	10x_3'_v3-lymph_node_(10x_3'_v3)-myeloid-myeloid_granulocytic-neutrophil\|lymph_node_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type	IGSF6 GLT1D1 LRRK2 SLC26A8 OSM TLR4 WDFY3	4.63e-05	189	222	7	235c24eeab5139f5821fccd5c879d8787682f4ef
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	HPSE2 GDNF ADRA1A DMD AKAP6 FRY P2RX1	4.63e-05	189	222	7	7fbe855bfdb47d35e040b04a80fe4b729a3764e8
ToppCell	facs-Lung-nan-3m-Endothelial-Capillary_Aerocyte_endothelial_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SLC30A1 GPR146 SCN7A CX3CL1 ATP13A2 ARHGAP6 FRY	4.63e-05	189	222	7	09dd2b3d89416192e84abe302a6237b8f3fdcb6e
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell-\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	HPSE2 GDNF ADRA1A DMD AKAP6 FRY P2RX1	4.63e-05	189	222	7	06b35abecd29f902cf251fcc1f6ad33db7ab08a2
ToppCell	Control-Endothelial-VE_Capillary_B\|Endothelial / Disease state, Lineage and Cell class	LRCH1 CX3CL1 SYNE1 SRGAP2 ANKRD44 ARHGAP6 CD274	4.79e-05	190	222	7	7f3f419fffe02934b6f27b697f7a6401072491ed
ToppCell	RV-08._Macrophage\|World / Chamber and Cluster_Paper	RIN3 SCN9A KNL1 SRGAP2 FAM111A TLR4 MYO1F	5.11e-05	192	222	7	a1b5dc5beb97a23729b97b54fb4574d10d8fbfb3
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	HPSE2 ADRA1A DMD AKAP6 FRY P2RX1 FRZB	5.46e-05	194	222	7	5c3b2b05d1e4f146551fe4c920263d8e6ca34de3
ToppCell	RA-03._Atrial_Cardiomyocyte\|RA / Chamber and Cluster_Paper	MYLK3 RABGAP1L SCN5A DMD AKAP6 MYH7B FRY	5.46e-05	194	222	7	c3535f7cc0076653c72db582047cff053c322397
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell-\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	HPSE2 ADRA1A DMD AKAP6 FRY P2RX1 FRZB	5.46e-05	194	222	7	ab9cad697f9209d2889bc02b43b502dfeb2ebfef
ToppCell	COVID-19-Heart-CM_2\|Heart / Disease (COVID-19 only), tissue and cell type	ADRA1A MYLK3 SCN5A DMD AKAP6 MYH7B FRY	5.64e-05	195	222	7	75fc81bddb246dca3b437fb60827b1d4fe416405
ToppCell	COVID-19-Heart-CM_1\|Heart / Disease (COVID-19 only), tissue and cell type	ADRA1A MYLK3 SCN5A DMD FHIP1A AKAP6 MYH7B	5.64e-05	195	222	7	f1ef50331eda8f1239dba6ea970df4eaccf032f1
ToppCell	3'-GW_trimst-1-SmallIntestine-Neuronal-neurons_A-Branch_A3_(IPAN/IN)\|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	KIF1A SCN9A KCNQ3 DOC2B AKAP6 CARMIL2 TMEM35A	5.64e-05	195	222	7	5a6a5048af638872700b76b7c71a8fa3fb8d3772
ToppCell	Control-Myeloid-ncMonocyte\|World / Disease state, Lineage and Cell class	TET2 RIN3 LRRK2 HPS3 P2RX1 P2RY2 MYO1F	5.64e-05	195	222	7	b4444b67a709e82b8e2ee510924c3152cb88b051
ToppCell	BL-critical-LOC-Myeloid-Neutrophil\|LOC / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	IGSF6 GLT1D1 LRRK2 IVNS1ABP OSM TLR4 WDFY3	5.82e-05	196	222	7	f64d7fed31e418c55fe946744d78c3cbecec9bbf
ToppCell	5'-GW_trimst-1.5-SmallIntestine-Neuronal-neurons_A-Branch_A2_(IPAN/IN)\|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	KIF1A SCN9A KCNQ3 DOC2B AKAP6 CARMIL2 TMEM35A	5.82e-05	196	222	7	36b4f08fc038dfde6343ff0869e1a027d882adb5
ToppCell	renal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	LRRK2 DNAH14 CLCN5 FHIP1A IVNS1ABP ARHGAP6 MAP3K21	5.82e-05	196	222	7	6ce74aa3f0ce3ca284b67e5a4660ffd2cc9611e0
ToppCell	BL-critical-LOC-Myeloid\|LOC / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	IGSF6 GLT1D1 LRRK2 IVNS1ABP OSM TLR4 WDFY3	6.01e-05	197	222	7	932a7fae4979b561688e6222505df0f4e510ab11
ToppCell	Smart-start-Cell-Wel_seq-Non-neoplastic-Myeloid-TAM-MG-TAM-MG_pro-infl_II-F\|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	CCDC88B ITPR2 SRGAP2 FMNL3 TLR4 CD274 NLRP4	6.01e-05	197	222	7	b597c292fc1cb381a4325fed15a32966c38def28
ToppCell	Smart-start-Cell-Wel_seq-Non-neoplastic-Myeloid-Mono-Mono_naive-E\|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	GLT1D1 ADRA1A ZDHHC18 IVNS1ABP OSM TLR4 MYO1F	6.01e-05	197	222	7	d2b2eaa6f7294ff56b84a69c8727c7e0f9fd0466
ToppCell	saliva-Severe-critical_progression_d28-40-Myeloid-Granulocytic-Neutrophil-Neu_c1-IL1B\|Severe-critical_progression_d28-40 / Compartment, severity and other cell annotations on 10x 3' data (130k)	IGSF6 LRRK2 ZDHHC18 IVNS1ABP OSM MYO1F WDFY3	6.01e-05	197	222	7	340ce4fef244176fb52e38ffbcbdfda5ac3467dd
ToppCell	BL\|World / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	IGSF6 GLT1D1 LRRK2 IVNS1ABP OSM TLR4 MYO1F	6.01e-05	197	222	7	1acf0191fa0a25cd20bfd9ea7bf727a1555986a1
ToppCell	NS-critical-d_07-13-Myeloid-Neutrophil\|d_07-13 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	IGSF6 LRRK2 ZDHHC18 IVNS1ABP OSM TLR4 MYO1F	6.01e-05	197	222	7	f38037dfa6c33e9336130d0cc65eaba0f120efb9
ToppCell	severe-HLA-DR+_CD83+_Monocyte\|severe / Cohort 1 (10x PBMC) with disease condition, cell group and cell class	TET2 IGSF6 LRRK2 SRGAP2 TLR4 MYO1F WDFY3	6.21e-05	198	222	7	a77f3440d7fb6a50066abc7e9ad59e83798ef13d
ToppCell	10x3'2.3-week_17-19-Mesenchymal_myocytic-stroma-muscle_stem_cell\|week_17-19 / cell types per 3 fetal stages;per 3',per 5'	CTSF CLCN5 SCN7A DMD AKAP6 GXYLT2 SSPN	6.21e-05	198	222	7	55e583321f60c95898d93cd0d2615c6692db52ec
ToppCell	Bronchial-NucSeq-Epithelial-Epi_alveolar\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	LRRK2 DNAH14 SLC9C1 KCNQ3 FHIP1A ACSS3 MYO1B	6.41e-05	199	222	7	725610310e5c5fd7120c0be9acb55bf152026ddd
ToppCell	LPS_IL1RA_TNF-Hematopoietic_Myeloid-Granulocytic_cells-Neutrophils\|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type	IGSF6 LRRK2 CCDC88B OSM TLR4 MYO1F CD274	6.41e-05	199	222	7	8c2ab13b5fffbab3da37041a7000d6537fc4db09
ToppCell	Bronchial-10x5prime-Stromal-Fibroblastic-Fibro_immune_recruiting\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	CTSF ADRA1A SCN7A FGFR1 SRPX FRZB CRB2	6.41e-05	199	222	7	0cdbedf09ec72734b86ddab3fec562e066afed92
ToppCell	facs-Marrow-B-cells-3m-Myeloid-granulocyte\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MYO7B HPSE2 GDNF TRANK1 SCN9A IGDCC3	6.47e-05	137	222	6	4dcb15de821439011df1bb0bbd7682d674bd725d
ToppCell	facs-Marrow-B-cells-3m-Myeloid-granulocyte\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MYO7B HPSE2 GDNF TRANK1 SCN9A IGDCC3	6.47e-05	137	222	6	c05ceeb7b483324604cb3f647d2da2b3786071b1
ToppCell	mild-HLA-DR+_CD83+_Monocyte\|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class	TET2 IGSF6 LRRK2 SRGAP2 TLR4 PTCH2 WDFY3	6.61e-05	200	222	7	934c2efc780318c66d667ca75be0de350361d351
ToppCell	LPS_IL1RA_TNF-Hematopoietic_Myeloid-Granulocytic_cells\|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type	IGSF6 LRRK2 CCDC88B OSM TLR4 MYO1F CD274	6.61e-05	200	222	7	1592ca96c59eb053d0f0915afb337db9f3a40c91
ToppCell	10x_3'_v3-blood_(10x_3'_v3)-myeloid-myeloid_granulocytic-neutrophil\|blood_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type	GLT1D1 LRRK2 ZDHHC18 SYNE1 LRP10 MYO1F WDFY3	6.61e-05	200	222	7	6beabd5bad042d4d65c89c2f537c7376230f7c08
ToppCell	LPS_IL1RA-Mesenchymal_myocytic-Myofibroblastic\|LPS_IL1RA / Treatment groups by lineage, cell group, cell type	HPSE2 GDNF SLC9C1 DMD SLITRK6 SYNE1 SSPN	6.61e-05	200	222	7	87827041663013f5e7273168dc8709d69840e7ce
ToppCell	LPS_IL1RA-Mesenchymal_myocytic-Myofibroblastic-Myofibroblast\|LPS_IL1RA / Treatment groups by lineage, cell group, cell type	HPSE2 GDNF SLC9C1 DMD SLITRK6 SYNE1 SSPN	6.61e-05	200	222	7	8988f113708eef7d9d2a6a6c1bcfd7c8f9804d3e
ToppCell	10x_3'_v3-blood_(10x_3'_v3)-myeloid-myeloid_granulocytic\|blood_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type	GLT1D1 LRRK2 ZDHHC18 SYNE1 LRP10 MYO1F WDFY3	6.61e-05	200	222	7	026495aa7f1e7528a01d9199475cfc393677fc60
ToppCell	LPS_only-Mesenchymal_myocytic\|LPS_only / Treatment groups by lineage, cell group, cell type	HPSE2 DMD SLITRK6 AKAP6 SYNE1 SSPN FRZB	6.61e-05	200	222	7	8bc9923f82bfb836e2f524204c92050edeae8ca5
ToppCell	control-HLA-DR-_S100A+_Monocyte\|control / Cohort 1 (10x PBMC) with disease condition, cell group and cell class	TET2 IGSF6 GLT1D1 LRRK2 RNPEP TLR4 WDFY3	6.61e-05	200	222	7	9e3e13a68bc1110fa000ec2d80f4c654ddbce17e
ToppCell	Frontal_cortex-Neuronal-Inhibitory-iN2(Gad1Gad2)-Synpr\|Frontal_cortex / BrainAtlas - Mouse McCarroll V32	DENND2A ADRA1B SCN5A SCN7A SCN9A GRIN2D	7.02e-05	139	222	6	408bc31aa5e1c2b379f79198fe8b5411f8d7bd08
ToppCell	PBMC_fresh-frozen-Severe-critical_convalescent_d14-21-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD4_c07-AHNAK\|Severe-critical_convalescent_d14-21 / Compartment, severity and other cell annotations on 10x 3' data (130k)	KNL1 ATP23 CCNJ DMBX1 OSM WDR86	8.86e-05	145	222	6	c0894c738815ff54790caddb4bccfa1503fd555b
ToppCell	facs-Lung-Endomucin-24m-Endothelial-Capillary_Type_1_Cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GABRG1 HPSE2 SLC9C1 SCN9A LARS2 MYO15A	8.86e-05	145	222	6	96712c68ab759d7ade0d912581a1a7c25dc6def8
ToppCell	facs-Marrow-B-cells-24m-Myeloid-granulocytopoietic_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	IGSF6 TTC21A MFSD6L GPR142 SYNE1 MYO1B	1.23e-04	154	222	6	71ffc23a2e02e27cabbdbeaa622e59e9f4a4cd9d
ToppCell	facs-Marrow-B-cells-24m-Myeloid-granulocytopoietic_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	IGSF6 TTC21A MFSD6L GPR142 SYNE1 MYO1B	1.23e-04	154	222	6	46155f36d3983f637b55d7525b675c8828f6ab2e
ToppCell	343B-Lymphocytic-NK_cells-NK_cell_B0\|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)	ANKRD65 SCN9A MLH1 CX3CL1 CRHR1 ARHGAP6	1.28e-04	155	222	6	583cfaa41c755c63aee312eb442e9d97f645d5f7
ToppCell	kidney_cells-Renal_AKI_(acute_kidney_injury)-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell-Distal_Convoluted_Tubule_Cell_Type_1\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	LRCH1 CLCN5 SCN7A OGT SGK2 IVNS1ABP	1.32e-04	156	222	6	4d2679e7639758c49fc25a2deb9109b08f0a3e57
ToppCell	368C-Fibroblasts-Fibroblast-F-\|368C / Donor, Lineage, Cell class and subclass (all cells)	MBTPS2 SCN5A LOXL3 KNL1 RFC3 CD274	1.37e-04	157	222	6	982e6ea78c7dabdb7c07c4a5fb2425d5e45b5b94
ToppCell	PND28-Immune-Immune_Lymphocytic_T/NK-Lymphocytic_B-B-B_prolif\|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	PRUNE1 MED12 MARS2 CARMIL2 ANKRD10 HPS3	1.37e-04	157	222	6	6730b775308f45a2f3946016bdbb7f8e5b5efe49
ToppCell	368C-Fibroblasts-Fibroblast-F\|368C / Donor, Lineage, Cell class and subclass (all cells)	MBTPS2 SCN5A LOXL3 KNL1 RFC3 CD274	1.37e-04	157	222	6	74038192f016f95f80e0189035ee8ccc22ceb1b8
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Cortical_Thick_Ascending_Limb_Cell\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	DENND2A CCNP SLC9C1 CLCN5 FHIP1A ARHGAP6	1.57e-04	161	222	6	4bb7bae54ba3bdf46b525c01f5ad3db8e49819cb
ToppCell	Globus_pallidus-Neuronal-Excitatory-eN3(Slc17a7_Gad1Gad2)\|Globus_pallidus / BrainAtlas - Mouse McCarroll V32	LRRK2 KLHL34 DOC2B SH2D5 ZFYVE28 KCNH5	1.57e-04	161	222	6	ebcd5066e82b7760b9da6adc02d11258d1309dab
ToppCell	368C-Myeloid-Dendritic-cDC1\|Dendritic / Donor, Lineage, Cell class and subclass (all cells)	ANO9 CLCN1 FADS6 CCNJ CCNF GXYLT2	1.68e-04	163	222	6	299ac2463b7f58eee419d822a2a2d64b973d87e9
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Immune-Myeloid-Granulocytic-Mast_Cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	PARP4 ALS2 ANKRD44 P2RX1 OR11A1 CD274	1.74e-04	164	222	6	2c48c6e4eeee845f0563982d0bfa2a176ca5ef61
ToppCell	ILEUM-non-inflamed-(3)_MNP-(3)_pDC\|(3)_MNP / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)	GLT1D1 SCN9A FHIP1A CCN3 ATP13A2 CRB2	1.92e-04	167	222	6	8ddf9da71a7c4ed53588435db826563a24cee616
ToppCell	PBMC_fresh-frozen-Mild-Moderate_progression_d02_child-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD4_c03-ITGA4\|Mild-Moderate_progression_d02_child / Compartment, severity and other cell annotations on 10x 3' data (130k)	TTC8 MBTPS2 MED12 NELFA CCNF MYO15A	1.98e-04	168	222	6	ca94b29c1030484143a77f2df06dad74d2c6136e
ToppCell	Mid-temporal_gyrus_(MTG)-Neuronal-Glutamatergic_Excit-Glut_A_(CT)-Glut_CT2_L6_FEZF2-Exc_L6_FEZF2_SLITRK6\|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	GABRG1 FGFR1 SLITRK6 FHIP1A DOC2B ARHGAP6	2.04e-04	169	222	6	1c9e54e7b14eb99996590fb93b257cf881a9f184
ToppCell	PND03-Immune-Immune_Myeloid-Monocytic-Macrophage-iMON-iMON_G2M\|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	IGSF6 KNL1 GPR21 CCNF FAM111A MYO1F	2.04e-04	169	222	6	4db49b7eaea34e6558ee73b01e76315e99cc880b
ToppCell	PND03-Mesenchymal-Mesenchymal_structural-Fibroblastic-AF1-AF1_prolif\|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	GABRG1 SLC38A5 ADRA1B TONSL RFC3 MACF1	2.11e-04	170	222	6	e20568c8f3f17d94de78229617eb2f7e4c5af2bc
ToppCell	droplet-Fat-Bat\|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	INTS1 SMYD4 R3HCC1L KCNQ3 CCNJ PRAMEF8	2.11e-04	170	222	6	c4ecdfc2b4710da0a5fbb20e9df02536023badb1
ToppCell	COVID-19-Heart-CM_+_Macrophage\|COVID-19 / Disease (COVID-19 only), tissue and cell type	MYLK3 SCN5A DMD AKAP6 MYH7B FRY	2.11e-04	170	222	6	3f15242a1d3e4e9871d9170b2ef05842fb609c29
ToppCell	droplet-Fat-Bat-18m\|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	INTS1 SMYD4 R3HCC1L KCNQ3 CCNJ PRAMEF8	2.11e-04	170	222	6	c720d81bc29a8fd1f1249c6af408471d561f1d5d
ToppCell	facs-Large_Intestine-Proximal-3m-Epithelial-Brush_cell_of_epithelium_proper_of_large_intestine\|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CCDC88B ITPR2 TMEM245 MYO1B CCNJ P2RX1	2.11e-04	170	222	6	17bd7fd25a2657cb536ad47e294332920f759e95
ToppCell	severe-Myeloid-Eosinophils\|severe / Cohort 2 (Rhapsody WB + PBMC) with disease condition, lineage and cell classs	SCN7A ADGRE4P PLA2G6 SYNE1 ALS2 FRY	2.11e-04	170	222	6	863f0266d5837cdbc3e09a3fe6a99dd3e6261674
ToppCell	PND10-Immune-Immune_Myeloid-Granulocytic-Basophil-Basophil_mature\|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	IGSF6 MYLK3 SYNE1 OSM P2RX1 MYO1F	2.25e-04	172	222	6	c05af6e559f6af0fb15cefa03ffa1413e98a1a4a
ToppCell	PND10-Immune-Immune_Myeloid-Granulocytic-Basophil\|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	IGSF6 MYLK3 SYNE1 OSM P2RX1 MYO1F	2.25e-04	172	222	6	953b05f776348cff784e79c93df65841939d880f
ToppCell	Bronchial_Brush-Epithelial-Ionocytes\|Epithelial / Tissue, Lineage and Cell class of Lung Cells from 10X	KIF1A MFSD6L ITPR2 SCN7A SCN9A KCNH5	2.32e-04	173	222	6	e1de849dcd96063136bdac87e050ddbd55cabdcc
ToppCell	Bronchial_Brush-Epithelial-Ionocytes\|Bronchial_Brush / Tissue, Lineage and Cell class of Lung Cells from 10X	KIF1A MFSD6L ITPR2 SCN7A SCN9A KCNH5	2.32e-04	173	222	6	f2a8f4918c1fb68d98bc3f33cd624de0f0f11e06
ToppCell	Mid-temporal_gyrus_(MTG)-Neuronal-Inh_GABAergic-i_Gaba_2-GABA_PAX6-Inh_L1-3_PAX6_NABP1\|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	GABRG1 DENND2A ADRA1A SCN7A FHIP1A ARHGAP6	2.32e-04	173	222	6	0d38206e25434386b1aec2078067efc67b496c10
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	HPSE2 ADRA1A SCN5A DMD AKAP6 P2RX1	2.47e-04	175	222	6	d52794426f2703a80e91ae0a8ff2d8e0ce4aa4a8
ToppCell	P03-Mesenchymal-developing_mesenchymal_cell-mesenchymal_immature_unknown_1\|P03 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	GABRG1 SLC38A5 ADRA1B SCN7A SRPX MACF1	2.47e-04	175	222	6	282f09bbdfa70d93b3f66591dcfb84c5ee0268c7
Drug	Farial	ADRA1B ADRA1A ELANE	8.78e-07	3	219	3	CID000065979
Drug	C75; Down 200; 10uM; MCF7; HT_HG-U133A	ZZEF1 PLA2G6 DDX51 SKIL GSPT1 SSPN FRZB MYO1F MYO15A CFAP69	1.86e-05	193	219	10	6394_DN
Drug	Ozagrel hydrochloride [78712-43-3]; Up 200; 15.2uM; HL60; HT_HG-U133A	KIF1A AUP1 INTS1 PEX10 PRUNE1 PLA2G6 SZT2 FPGS NUMA1 CCNF	2.04e-05	195	219	10	2942_UP
Drug	(-)-Cinchonidine [485-71-2]; Down 200; 13.6uM; PC3; HT_HG-U133A	CUL9 MAPK8IP3 PRUNE1 CLCN5 FGFR1 CCN3 LMF1 NUMA1 ATP13A2 CFAP69	2.13e-05	196	219	10	5833_DN
Drug	Thioproperazine dimesylate [2347-80-0]; Up 200; 6.2uM; MCF7; HT_HG-U133A	IGSF6 RABGAP1 VPS16 RABGAP1L SCN5A FGFR1 DSC3 NUMA1 DIS3 WDFY3	2.13e-05	196	219	10	2236_UP
Drug	molindone	DARS1 ADRA1B ADRA1A LOXL3 EIF2AK3	2.33e-05	36	219	5	CID000023897
Drug	1-adamantanecarboxylic acid	MLH1 SYNE1 PC	2.99e-05	7	219	3	CID000013235
Drug	clenbuterol	ADRA1B ADRA1A SCN7A SCN9A DMD MYH7B MYO1B MYO15A	7.17e-05	142	219	8	CID000002783
Drug	phenethanolamine	ADRA1B ADRA1A LOXL3 CRHR1 LRCH4	7.82e-05	46	219	5	CID000001000
Drug	isoproterenol	AVPR2 HPSE2 ADRA1B ADRA1A CLCN1 CLCN5 SCN5A TONSL SCN7A SCN9A DMD AKAP6 MYH7B MYO1B P2RX1 P2RY2 TNFAIP1 MYO15A	8.95e-05	669	219	18	CID000003779
Drug	St-1913	ADRA1B ADRA1A	9.21e-05	2	219	2	CID000123528
Drug	Neldazosin	ADRA1B ADRA1A	9.21e-05	2	219	2	CID000065908
Drug	DL-028	ADRA1B ADRA1A	9.21e-05	2	219	2	CID005487531
Drug	quinazosin	ADRA1B ADRA1A	9.21e-05	2	219	2	CID000027486
Drug	Ranolazine	SCN5A SCN9A	9.21e-05	2	219	2	DB00243
Drug	hydroxyphenacetyl aminoclonidine	ADRA1B ADRA1A	9.21e-05	2	219	2	CID000173558
Drug	Midodrine	ADRA1B ADRA1A	9.21e-05	2	219	2	DB00211
Drug	sulfonterol	ADRA1B ADRA1A	9.21e-05	2	219	2	CID000170372
Drug	AC1L27FT	ADRA1B ADRA1A	9.21e-05	2	219	2	CID000016192
Drug	paveril	ADRA1B ADRA1A	9.21e-05	2	219	2	CID000006855
Drug	tolazine	ADRA1B ADRA1A	9.21e-05	2	219	2	CID000101252
Drug	piclonidine	ADRA1B ADRA1A	9.21e-05	2	219	2	CID000068914
Drug	Lidanserin	ADRA1B ADRA1A	9.21e-05	2	219	2	CID000068919
Drug	FCE 22716	ADRA1B ADRA1A	9.21e-05	2	219	2	CID000125720
Drug	SKF 101253	ADRA1B ADRA1A	9.21e-05	2	219	2	CID000135152
Drug	ASL-7022	ADRA1B ADRA1A	9.21e-05	2	219	2	CID000173406
Drug	hoquizil	ADRA1B ADRA1A	9.21e-05	2	219	2	CID000030690
Drug	Methoxamine	ADRA1B ADRA1A	9.21e-05	2	219	2	DB00723
Drug	Prestwick_774	ADRA1B ADRA1A	9.21e-05	2	219	2	CID006420011
Drug	compound 44-549	ADRA1B ADRA1A	9.21e-05	2	219	2	CID000191431
Drug	5-dembs	ADRA1B ADRA1A	9.21e-05	2	219	2	CID000130379
Drug	levomepromazine sulfoxide	ADRA1B ADRA1A	9.21e-05	2	219	2	CID000165566
Drug	R 56	ADRA1B ADRA1A	9.21e-05	2	219	2	CID009578362
Drug	dihydrolysergic acid amide	ADRA1B ADRA1A	9.21e-05	2	219	2	CID000151000
Drug	St-404	ADRA1B ADRA1A	9.21e-05	2	219	2	CID000191786
Drug	AC1MBW4N	ADRA1B ADRA1A	9.21e-05	2	219	2	CID002732234
Drug	Myordil	ADRA1B ADRA1A	9.21e-05	2	219	2	CID000011282
Drug	5-cfmbs	ADRA1B ADRA1A	9.21e-05	2	219	2	CID000183818
Drug	IK29	ADRA1B ADRA1A	9.21e-05	2	219	2	CID000183825
Drug	pyrroxan	ADRA1B ADRA1A	9.21e-05	2	219	2	CID000036302
Drug	dihydroergonine	ADRA1B ADRA1A	9.21e-05	2	219	2	CID000193205
Drug	Indoramin	ADRA1B ADRA1A	9.21e-05	2	219	2	ctd:D007217
Drug	penta-O-ethylquercetin	ADRA1B ADRA1A	9.21e-05	2	219	2	CID000133942
Drug	AC1MO93T	ADRA1B ADRA1A MBTPS2 TNFAIP1	1.05e-04	26	219	4	CID003316606
Drug	normetanephrine	GDNF ADRA1B ADRA1A LOXL3 FRZB	1.06e-04	49	219	5	CID000001237
Drug	Hycanthone [3105-97-3]; Down 200; 11.2uM; PC3; HT_HG-U133A	CTSF ITPR2 CLCN5 MBTPS2 ZNF589 SZT2 NUMA1 MYO1F SNAPC4	1.10e-04	193	219	9	4630_DN
Drug	(R)-(+)-Atenolol [56715-13-0]; Up 200; 15uM; MCF7; HT_HG-U133A	RABGAP1 MAPK8IP3 ITPR2 ZFYVE9 RABGAP1L FGFR1 NUMA1 TUT1 CRHR1	1.19e-04	195	219	9	2855_UP
Drug	Berberine chloride [633-65-8]; Down 200; 10.8uM; PC3; HT_HG-U133A	GCDH FGFR1 CCN3 ZDHHC18 LMF1 SCYL3 IVNS1ABP TNFAIP1 MAST3	1.24e-04	196	219	9	7143_DN
Drug	Sulfadoxine [2447-57-6]; Down 200; 12.8uM; MCF7; HT_HG-U133A	KIF1A GCDH RABGAP1 LRCH1 FGFR1 MED12 SKIL SSPN PC	1.24e-04	196	219	9	3547_DN
Drug	Cyclosporin A [59865-13-3]; Down 200; 3.4uM; PC3; HT_HG-U133A	KIF1A PEX10 CUL9 RABGAP1 MAPK8IP3 R3HCC1L FGFR1 SYNE1 TUT1	1.24e-04	196	219	9	4586_DN
Drug	Perphenazine [58-39-9]; Down 200; 10uM; MCF7; HT_HG-U133A	CTSF PEX10 ITPR2 ZNF589 PLA2G6 FGFR1 LMF1 TNFAIP1 WDFY3	1.28e-04	197	219	9	1540_DN
Drug	Lynestrenol [52-76-6]; Down 200; 14uM; MCF7; HT_HG-U133A	CTSF RABGAP1 LRCH1 ITPR2 ZFYVE9 FGFR1 ZDHHC18 WDFY3 MAST3	1.33e-04	198	219	9	1537_DN
Drug	Clindamycin hydrochloride [21462-39-5]; Up 200; 8.6uM; PC3; HT_HG-U133A	CTSF RIN3 IGSF6 KIF1A PEX10 TBC1D16 ADRA1A ZNF589 DMD	1.33e-04	198	219	9	5815_UP
Drug	Prazosin hydrochloride [19237-84-4]; Up 200; 9.6uM; PC3; HT_HG-U133A	DENND2A R3HCC1L MBTPS2 PLA2G6 FGFR1 SZT2 IVNS1ABP CFAP69 NNT	1.33e-04	198	219	9	6315_UP
Drug	felodipine; Down 200; 10uM; MCF7; HG-U133A	CUL9 SLC30A1 CLCN5 KCNQ3 FGFR1 CCN3 LMF1 SKIL NLRP2	1.39e-04	199	219	9	337_DN
Drug	bretylium	ADRA1B ADRA1A LOXL3 RNPEP	1.42e-04	28	219	4	CID000002431
Disease	generalized epilepsy with febrile seizures plus 2 (implicated_via_orthology)	SCN5A SCN7A SCN9A	3.94e-05	10	207	3	DOID:0111294 (implicated_via_orthology)
Disease	Dravet syndrome (implicated_via_orthology)	SCN5A SCN7A SCN9A	3.94e-05	10	207	3	DOID:0080422 (implicated_via_orthology)
Disease	generalized epilepsy with febrile seizures plus (implicated_via_orthology)	SCN5A SCN7A SCN9A	7.14e-05	12	207	3	DOID:0060170 (implicated_via_orthology)
Disease	Bipolar Disorder	GABRG1 GDNF ADRA1A TRANK1 KCNQ3 PLA2G6 FGFR1 SYNE1 LARS2 CRHR1 TLR4 PC	1.52e-04	477	207	12	C0005586
Disease	Neuropathy, Hereditary Sensory And Autonomic, Type IIA	KIF1A SCN9A	2.91e-04	4	207	2	C2752089
Disease	Hereditary sensory and autonomic neuropathy type 2	KIF1A SCN9A	2.91e-04	4	207	2	cv:C5574675
Disease	Neuropathy, hereditary sensory and autonomic, type 2A	KIF1A SCN9A	2.91e-04	4	207	2	cv:C2752089
Disease	NEUROPATHY, HEREDITARY SENSORY AND AUTONOMIC, TYPE IIA	KIF1A SCN9A	2.91e-04	4	207	2	201300
Disease	platelet component distribution width	DENND2A RIN3 LRRK2 SLC30A1 ZZEF1 LRCH1 TRANK1 MLH1 PLA2G6 VPS18 ATP23 SYNE1 P2RY2 MACF1 EEF1AKMT2	3.08e-04	755	207	15	EFO_0007984
Disease	Parkinson disease	LRRK2 PLA2G6 ATP13A2	4.75e-04	22	207	3	cv:C0030567
Disease	polyarteritis nodosa (is_marker_for)	GDNF CX3CL1	4.83e-04	5	207	2	DOID:9810 (is_marker_for)
Disease	Duchenne muscular dystrophy (is_marker_for)	PLA2G6 DMD	4.83e-04	5	207	2	DOID:11723 (is_marker_for)
Disease	Autosomal Dominant Parkinsonism	LRRK2 GDNF ATP13A2	9.79e-04	28	207	3	C0752098
Disease	Autosomal Dominant Juvenile Parkinson Disease	LRRK2 GDNF ATP13A2	9.79e-04	28	207	3	C0752097
Disease	Parkinsonism, Experimental	LRRK2 GDNF ATP13A2	9.79e-04	28	207	3	C0752101
Disease	Autosomal Recessive Parkinsonism	LRRK2 GDNF ATP13A2	9.79e-04	28	207	3	C0752100
Disease	Familial Juvenile Parkinsonism	LRRK2 GDNF ATP13A2	9.79e-04	28	207	3	C0752104
Disease	Ramsay Hunt Paralysis Syndrome	LRRK2 GDNF ATP13A2	9.79e-04	28	207	3	C0242423
Disease	PARKINSON DISEASE 2, AUTOSOMAL RECESSIVE JUVENILE	LRRK2 GDNF ATP13A2	9.79e-04	28	207	3	C1868675
Disease	Parkinsonism, Juvenile	LRRK2 GDNF ATP13A2	1.20e-03	30	207	3	C0752105
Disease	Parkinsonian Disorders	LRRK2 GDNF ATP13A2	1.20e-03	30	207	3	C0242422
Disease	Polydactyly	IFT172 TTC8 CEP120 MBTPS2 FGFR1	1.44e-03	117	207	5	C0152427
Disease	Colorectal Carcinoma	TET2 MYLK3 SACS MLH1 DMD AKAP6 VPS18 SYNE1 FPGS RTN4 MYO1B HPS3 TLR4	1.46e-03	702	207	13	C0009402
Disease	acoustic neuroma (is_marker_for)	GDNF FGFR1	1.71e-03	9	207	2	DOID:12689 (is_marker_for)
Disease	long QT syndrome (implicated_via_orthology)	KCNQ3 ARHGAP6	2.12e-03	10	207	2	DOID:2843 (implicated_via_orthology)
Disease	Jeune thoracic dystrophy	IFT172 CEP120	2.58e-03	11	207	2	C0265275
Disease	Parkinsonism (is_implicated_in)	LRRK2 GDNF	2.58e-03	11	207	2	DOID:0080855 (is_implicated_in)
Disease	Nerve Degeneration	LRRK2 ADRA1B GRIN2D ATP13A2	2.81e-03	83	207	4	C0027746
Disease	Parkinson Disease, Secondary Vascular	GDNF ATP13A2	3.09e-03	12	207	2	C0751414
Disease	Atherosclerotic Parkinsonism	GDNF ATP13A2	3.09e-03	12	207	2	C0751415
Disease	Secondary Parkinson Disease	GDNF ATP13A2	3.09e-03	12	207	2	C0030569
Disease	Dental enamel hypoplasia	MYH7B MAP3K21	3.09e-03	12	207	2	EFO_1001304
Disease	myotonia congenita (implicated_via_orthology)	CLCN1 MYH7B	3.09e-03	12	207	2	DOID:2106 (implicated_via_orthology)
Disease	Neurodegeneration with brain iron accumulation	PLA2G6 ATP13A2	3.63e-03	13	207	2	cv:C2931845
Disease	Short Rib-Polydactyly Syndrome	IFT172 CEP120	3.63e-03	13	207	2	C0036996
Disease	Hereditary Motor and Sensory-Neuropathy Type II	KIF1A SCN9A	3.63e-03	13	207	2	C0270914
Disease	Infantile Refsum Disease (disorder)	PEX10 PEX11B	3.63e-03	13	207	2	C0282527
Disease	pulmonary emphysema (implicated_via_orthology)	TLR4 ELANE	3.63e-03	13	207	2	DOID:9675 (implicated_via_orthology)
Disease	neurodegenerative disease (implicated_via_orthology)	UBR1 LRRK2 PLA2G6 MARS2 PTCH2	3.65e-03	145	207	5	DOID:1289 (implicated_via_orthology)
Disease	Schizophrenia	GDNF SLC26A8 ADRA1A TMEM245 KCNQ3 PLA2G6 FGFR1 MED12 WNK3 IL19 RTN4 GRIN2D LARS2 TLR4	3.98e-03	883	207	14	C0036341
Disease	neuroimaging measurement, brain volume measurement	RIN3 RABGAP1 GDNF ATP13A2 LRCH4 CRB2 KRTCAP2	4.21e-03	286	207	7	EFO_0004346, EFO_0006930
Disease	trimethylamine-N-oxide measurement	ITPR2 RTN4	4.22e-03	14	207	2	EFO_0010541
Disease	Saldino-Noonan Syndrome	IFT172 CEP120	4.22e-03	14	207	2	C0036069
Disease	Majewski Syndrome	IFT172 CEP120	4.22e-03	14	207	2	C0024507
Disease	Gastrointestinal Stromal Sarcoma	IFT172 DMD PTCH2	4.40e-03	47	207	3	C3179349
Disease	HSV2 virologic severity measurement	CEP120 SLITRK6	4.84e-03	15	207	2	EFO_0009010
Disease	myelodysplastic syndrome (implicated_via_orthology)	TET2 PRPF8	4.84e-03	15	207	2	DOID:0050908 (implicated_via_orthology)
Disease	Peroxisome biogenesis disorders	PEX10 PEX11B	4.84e-03	15	207	2	C1832200
Disease	Adrenoleukodystrophy, Neonatal	PEX10 PEX11B	4.84e-03	15	207	2	C0282525
Disease	sexual dimorphism measurement	TET2 KIF1A ZZEF1 GDNF TRANK1 CEP120 SOST ATP23 RTN4 ATP13A2 CD19 OR11A1 MYO1F MACF1 PC PPP6R3	5.16e-03	1106	207	16	EFO_0021796
Disease	Gastrointestinal Stromal Tumors	IFT172 DMD PTCH2	5.23e-03	50	207	3	C0238198
Disease	Zellweger Syndrome	PEX10 PEX11B	5.51e-03	16	207	2	C0043459
Disease	response to tenofovir	RIN3 ZNF589 SLC17A4	5.53e-03	51	207	3	EFO_0009279
Disease	age at menopause	SLC26A8 MYLK3 MED12 GEMIN5 CCNJ GSPT1 LRCH4	5.64e-03	302	207	7	EFO_0004704
Disease	epilepsy (implicated_via_orthology)	SCN5A SCN7A SCN9A GRIN2D KCNH5	5.97e-03	163	207	5	DOID:1826 (implicated_via_orthology)
Disease	renal fibrosis (implicated_via_orthology)	GPR21 TLR4	6.21e-03	17	207	2	DOID:0050855 (implicated_via_orthology)
Disease	protein C measurement	MYO7B MYH7B	6.21e-03	17	207	2	EFO_0004633
Disease	dermatomyositis (is_marker_for)	CX3CL1 TLR4	6.21e-03	17	207	2	DOID:10223 (is_marker_for)
Disease	vital capacity	TET2 DENND2A RIN3 KIF1A ZZEF1 R3HCC1L CEP120 EIF2AK3 CCN3 MYH7B SYNE1 ATP13A2 MYO1F SNAPC4 PC NNT NLRP4	6.51e-03	1236	207	17	EFO_0004312
Disease	cortical surface area measurement	MON2 TET2 RIN3 CUL9 LRCH1 TBC1D16 PCGF6 CEP120 RALBP1 MLH1 SMIM32 FGFR1 ATP13A2 CRHR1 FRZB MACF1 EEF1AKMT2 PC	6.79e-03	1345	207	18	EFO_0010736
Disease	nevus count	SLC30A1 PLA2G6	6.96e-03	18	207	2	EFO_0004632

Protein segments in the cluster

Peptide	Gene	Start	Entry
RHCLLLISTLGVFAL	C21orf62	6	Q9NYP8
HLFFVDTAGLREIVC	C1orf140	91	Q5VVS0
CLLAGDRSLADVIIH	RNPEP	311	Q9H4A4
DAIQCGHIDVARLLL	ANKRD16	211	Q6P6B7
AHFGKLECLVQLVRA	ANKRD10	66	Q9NXR5
RLLLGASVQCEHREL	CCDC88B	141	A6NC98
RSVCLHIFLQIAEAV	EIF2AK3	911	Q9NZJ5
ILIDRCGKHFGTILN	TNFAIP1	71	Q13829
RILQLACGEEHTLAL	ALS2	151	Q96Q42
RVVLQVACGAFHSLA	ALS2	201	Q96Q42
LSVLFGHVECLLVLL	ASB4	81	Q9Y574
ELTARAVHQIQACLL	CARMIL2	686	Q6F5E8
VLGNILVILSVACHR	ADRA1A	41	P35348
LQGVLLFVVHCLLNR	ADGRE4P	426	Q86SQ3
CAHGRVQVVTLLLDR	ANKRD18B	76	A2A2Z9
FLVQCIERLLIAHDN	CCNJ	226	Q5T5M9
IRSEIICAGFLIHAI	ACOT12	486	Q8WYK0
VGNILVILSVACNRH	ADRA1B	61	P35368
CQHLEQVLLGTIAFV	C1orf74	101	Q96LT6
LFDVHSILRVVLGAN	CD276	201	Q5ZPR3
TGFCDQRRLGLLLHD	DMD	3226	P11532
IRLAFVILFEHVALC	ANO9	701	A1A5B4
RLHRLQLLGVACLFV	CCNP	146	Q9H8S5
LHTVSCRNFESLVLL	NWD1	421	Q149M9
TGHERILLSQACLEI	R3HCC1L	156	Q7Z5L2
VVRDVACGANHTLVL	RCC2	331	Q9P258
EFLLNCLHRDLQGGI	RALBP1	406	Q15311
NERTHLVILGAILLC	CD274	236	Q9NZQ7
SCVFLAFVIVLLAHR	PCDHGA2	701	Q9Y5H1
GNISLVALIFTHCRL	OR5K2	41	Q8NHB8
AGQLDARLHELLCFL	ITPRIP	451	Q8IWB1
FISTLGLVDDRCVVH	ITPR2	26	Q14571
ALIHEGILFRLTFCN	OR5H8	156	P0DN80
VSFCRLRHLQVILLD	LRCH4	221	O75427
LIHRLFVCISGVADQ	ZFYVE28	726	Q9HCC9
VLRQGLACLQRLHVA	PEX10	166	O60683
NQSDCVLHRILGDFL	ANAPC7	471	Q9UJX3
IIDHFICDISLILQL	OR6C70	171	A6NIJ9
SLNGCRVTDEILHLV	PAPOLB	201	Q9NRJ5
FHLVGLGATLCAINI	OTOA	961	Q7RTW8
VFHIIDLLLCEGISV	RABGAP1	741	Q9Y3P9
RQTAALLHGTIILDC	PRUNE1	166	Q86TP1
CSLVNEIFRLHFGLK	ATP23	161	Q9Y6H3
VDGLVVALVAQLRFC	OR11A1	156	Q9GZK7
ERCIVSHLQELLARG	KLHL34	151	Q8N239
LQAAHILCRELGFTE	LOXL3	76	P58215
HIGVTCIIFCVLFLL	IGDCC3	646	Q8IVU1
IRFQKLHLACGSERL	LRP10	71	Q7Z4F1
RVLVALADGTLAIFH	MAPK8IP3	1011	Q9UPT6
AVIDNIRLCFHGLSS	NELFA	36	Q9H3P2
SVCKLDGLIHRFITL	INTS1	1831	Q8N201
AVLDGIFCVIFLHGR	IVNS1ABP	306	Q9Y6Y0
ELGLAEHQLRFTCRV	INTS11	501	Q5TA45
LCRVVAVHVENLLSA	MYO15A	3501	Q9UKN7
FAGCLQDVRVDGHLL	CRB2	576	Q5IJ48
ILCSVDNHGLRRCLI	IL19	16	Q9UHD0
HALVFLIVLGCLILA	KCNQ3	126	O43525
DGCLRALAVEFQTIH	KCNH5	556	Q8NCM2
LALFASGLIHRVCVT	KRTCAP2	81	Q8N6L1
CGNIVFVDLIEHLLS	CAND1	206	Q86VP6
RALGVAKLFHLVCGV	MFSD6L	11	Q8IWD5
FLVLHQLRCNGVLEG	MYH7B	736	A7E2Y1
GVLLLDQREIAHAAC	OR51B4	81	Q9Y5P0
ILGNLTILHVICTDA	OR51G1	41	Q8NGK1
ALIHEVLIFRLTFCN	OR5H2	161	Q8NGV7
LDVVLFTRQICEGVH	MYLK3	611	Q32MK0
HLAVVACGNRLEETL	GXYLT2	111	A0PJZ3
HIQRLELALLCFTVL	MS4A10	166	Q96PG2
AVLRTFGHLSLGQIC	MACF1	381	O94854
RDLIGFCLVHILFIV	LRCH1	701	Q9Y2L9
IQEVSCCLLHRLTLG	LRRK2	266	Q5S007
LEEFSLVVHHCRLLG	KNL1	2226	Q8NG31
CLEALVRGLADHVLQ	LRRC14B	86	A6NHZ5
LVLLFCELIRHDVFS	MED12	596	Q93074
RGCVLTAIHLNVTDL	GDNF	116	P39905
AAVLVVSRELTHLCL	NLRP2	861	Q9NX02
IGDVGVQLLCRALTH	NLRP4	876	Q96MN2
SVINGHTLCLRLLLE	ANKRD44	641	Q8N8A2
AAARGHLLAVQLLVT	ANKRD65	276	E5RJM6
HALLCVRINNIAVAV	GPR180	51	Q86V85
SVAFHCLLDLVRGIT	MON2	486	Q7Z3U7
HVLRILSQCGAGVFE	PARP4	1011	Q9UKK3
CSGLHLIFALNALRR	HPSE2	216	Q8WWQ2
ILFLTCISVHRCLGV	P2RY2	121	P41231
LCHSGRTFDAQIVII	GSPT1	386	P15170
LCEGLNIIFHVALAL	RABGAP1L	721	Q5R372
LHIAERCFSALGQVA	IFT172	641	Q9UG01
LRFLSCTVEADGIHL	SCYL3	66	Q8IZE3
FLGHLCVLEILITST	OR9A1P	61	Q8NGU1
CDTLHRLLQFLSIVA	ARHGAP6	516	O43182
VSFLEGHLDQLLRCL	PRAMEF12	276	O95522
RHTLFCGTLILQARA	ATP13A2	371	Q9NQ11
VSLALFRTLIGLHCE	FHIP1A	386	Q05DH4
RHLQTNLILFCVGAV	IGSF6	11	O95976
FGVVCAHVGETQRLL	HEATR5A	786	Q86XA9
DRFHLILGISVEFLC	HEATR5A	1551	Q86XA9
RQRGLLCDIVLHVAA	KLHL17	86	Q6TDP4
QGLLVGIVRCAHLAA	DOC2B	281	Q14184
RGAVCLHLLLTLVIF	DSC3	11	Q14574
LLLHLLGQVAATQRC	CCN3	21	P48745
ILHCLGRVLSLFEDE	CCNF	186	P41002
TEITLGLHACLQLGR	GCDH	341	Q92947
SVRHLVCVFASLLLE	DENND2A	751	Q9ULE3
VRLVFLLLTLHLGNC	GABRG1	21	Q8N1C3
SADNLHIFLLICGLR	GLT1D1	161	Q96MS3
DQLLIVVSILEGRHF	CEP120	6	Q8N960
IFCLCSLVGILHLQR	CD19	301	P15391
VQALLSRVVCHIRAL	DDX51	271	Q8N8A6
ESFLVHPGDLLQLRC	FGFR1	41	P11362
VHALTLAERLAGCTF	DMBX1	41	Q8NFW5
LAETRFCHVVQAGLE	EEF1AKMT2	251	Q5JPI9
KGLFILTCRHVIDSI	FAM111A	376	Q96PZ2
VCLVRGGHEIILAAF	FMNL3	276	Q8IVF7
DIFRKLGLRQCLVTH	CLCN5	771	P51795
CSFQVLDELGRHVLL	CTSF	106	Q9UBX1
GHCISLVALLVAFVL	CRHR1	126	P34998
TFCLLLRAINHTGTD	DNAH14	2951	Q0VDD8
CGVFLVTNSAIIHRL	GPR142	326	Q7Z601
RGLFVGDLVTHLQDC	MBTPS2	271	O43462
LGFIHHQIVELARDC	MAST3	211	O60307
FTVTLDQVLLRCLEH	FPGS	456	Q05932
LRLGLAVIHGEAQCT	PRPSAP1	191	Q14558
SEIVQELTCFLHRLA	CUL9	1051	Q8IWT3
HSAQLLLGCELRDLV	CUL9	1091	Q8IWT3
LVCNGLIHGIASFVR	ELANE	206	P08246
CEFTVLATRILHLLG	COPG1	446	Q9Y678
SVLHAVEGFALVLLC	FRY	736	Q5TBA9
RLLLCVQALVSVCHE	DNAAF5	496	Q86Y56
AHRLLVATVCTQFGL	GPR146	231	Q96CH1
LIISGNIIVIFVFHC	GPR21	41	Q99679
GLSAEDFVTLCIIHR	CFAP69	736	A5D8W1
VSFLEGHLDQLLRCL	PRAMEF8	276	Q5VWM4
VLRFCITVSHLNRAL	PEX11B	81	O96011
LCGALNLIRGFHAIE	SEC22A	201	Q96IW7
GFCSVRHGLALILQL	SLC17A4	31	Q9Y2C5
RHGLALILQLCNFSI	SLC17A4	36	Q9Y2C5
SLVDEFSLCGHRLII	SACS	1671	Q9NZJ4
ALTEGALCQHDLIRV	FAM126B	146	Q8IXS8
ERHGVDCAILALSLF	FADS6	51	Q8N9I5
TFAVCTEHRGILLQA	KIF1A	1641	Q12756
LITFFSGHLEQLIRC	PRAMEF13	276	Q5VWM6
GVLLLLSSIHFQCRR	OGT	56	O15294
SSHVFGCLEIFILIL	OR4C16	101	Q8NGL9
QDCSIFIKIIDRIHG	NUMA1	31	Q14980
IICGDHLLEQYQTLR	PCGF6	306	Q9BYE7
LRNLVQCGDFPHLLV	RFC3	26	P40938
HRLFVLVDGRCFQLA	RIN3	921	Q8TB24
SCVFLAFVIVLLAHR	PCDHGA1	701	Q9Y5H4
LRKLIFCQATIIGHA	OR52L2P	181	Q8NGH6
IIDHFICDLFQLLTL	OR4C6	171	Q8NH72
FLVLCRVLLNVIHEC	MAP3K4	616	Q9Y6R4
FHSLVGLAAVLTCIA	NNT	706	Q13423
IFGVATVLCDLLLLH	P2RX1	341	P51575
LGHVNCTIKELRRLF	RTN4	1096	Q9NQC3
VIVLGSLFFLVCHLV	TAS2R20	131	P59543
ILFDEVFHALSRCLG	SZT2	116	Q5T011
VCHVARNLAVEQLTL	MRPL44	166	Q9H9J2
LLTLGVFCHIALRLT	SMYD4	341	Q8IYR2
VFCHIALRLTLLVGF	SMYD4	346	Q8IYR2
LLDCQGHVVLTDFGL	SGK2	166	Q9HBY8
IVFCAAGIVVLVLHR	SLITRK6	621	Q9H5Y7
LFHGVLVCLITLVVN	SLC9C1	401	Q4G0N8
RCTSDQLHILKVLGI	SKIL	196	P12757
TGVASVLNLCEVLLH	SYNE1	7941	Q8NF91
VHEFVLQSELGVRLL	LARS2	866	Q15031
ALRIQLFIGLKAICH	HPS3	426	Q969F9
LQQPHLCLVLEFARG	MAP3K21	191	Q5TCX8
LITFFSGHLEQLIRC	PRAMEF14	276	Q5SWL7
IHLLLTCAGIAGIRA	SLC38A5	96	Q8WUX1
ILIAGCHSSIVRAFE	SLC26A8	756	Q96RN1
IQRHCGKVLFLGLLA	PTCH2	51	Q9Y6C5
VQILHLLLCRSFQLA	SH2D5	131	Q6ZV89
ESLVKILARGFCLHA	SCN5A	171	Q14524
VSGDRIHCLDILFAF	SCN9A	1831	Q15858
VALVVLFIGCQLRHS	SMIM32	66	A0A1B0GUA5
LGLTVCVLAVAFAAH	SSPN	131	Q14714
LITFFSGHLEQLIRC	PRAMEF1	276	O95521
FRLQSGICHLFRETL	DARS1	196	P14868
SVAHLAVELGIRECF	PLA2G6	121	O60733
LITFFSGHLEQLIRC	PRAMEF2	276	O60811
RVIHFIAVAVCLLGV	SLC35F2	161	Q8IXU6
QCGLDLRHITVVELV	SRPX	366	P78539
CIFLLFINHRLVEST	MLH1	256	P40692
ALCLVCLLVHTAFRV	SOST	6	Q9BQB4
CLLVHTAFRVVEGQG	SOST	11	Q9BQB4
IVHRLLAVAIGADCT	DIS3	786	Q9Y2L1
ATLGCVLHRLADLEQ	OSM	101	P13725
VGVDINICSEVLLRH	SRBD1	706	Q8N5C6
NICSEVLLRHIAGLN	SRBD1	711	Q8N5C6
GVASILRLCQHLLDD	AKAP6	1136	Q13023
LACARIGAIHSLIFG	ACSS3	186	Q9H6R3
SIFQSLLHCLLGRAR	CLCN1	766	P35523
LRLFLGIHVFLVSCA	AUP1	41	Q9Y679
GNAFHLCREVLRLTK	PRPF8	541	Q6P2Q9
VSFLEGHLDQLLRCL	PRAMEF7	276	Q5VXH5
IGDTNLAHQCFRLAL	TTC8	436	Q8TAM2
SIHNVCTEAVFLLLG	WDFY3	1831	Q8IZQ1
ILAIEQFEGLLGTHC	FRZB	66	Q92765
EVVVCFQLRHGNDLL	PLEKHG4B	971	Q96PX9
AALVQVFREALGCHI	TUT1	621	Q9H6E5
LNCGHFEVAELLLER	TONSL	606	Q96HA7
VCTLTGQVVLRDHFL	VPS18	346	Q9P253
LVVESCIRFISRHGL	SRGAP2	506	O75044
ALEQICGVFRVDLGH	TBC1D16	291	Q8TBP0
TVLCQDRVAHILLAV	VPS16	181	Q9H269
HESLQGQRLVFCLLE	GEMIN5	1111	Q8TEQ6
GQRLVFCLLELLSRH	GEMIN5	1116	Q8TEQ6
CLLSIDLFHVLVGAV	UBR1	1396	Q8IWV7
LGTVLHVALECLRVF	MARS2	506	Q96GW9
HVALECLRVFGTLLQ	MARS2	511	Q96GW9
SHQVILGLVCSFIER	TTC21A	311	Q8NDW8
HRLEGKFCDVSLLVQ	ZBTB9	41	Q96C00
VQVLLVHAATLICRG	TMEM245	171	Q9H330
HCVLLREFSVLTELL	ZZEF1	1051	O43149
IVFHGLIELCLANVA	SCN7A	576	Q01118
QLFHIDTAGCLEVVR	SNAPC4	796	Q5SXM2
VAGLLVNVLGLCLFH	SLC30A1	121	Q9Y6M5
CGRGFIVESVLRNHL	ZNF589	281	Q86UQ0
LLEFQFIHCGVVLAR	TRANK1	2411	O15050
RAGHTCEAAVIVILI	TET2	1216	Q6N021
CIQGLAGLEVHRLVL	TLR4	246	O00206
NFLHTQVEICIALIL	PPP6R3	386	Q5H9R7
FREHRGSVICLELVN	WDR86	231	Q86TI4
LAEELVRAGTHILCI	PC	726	P11498
IFACVVTHLTLRAQG	ZDHHC18	251	Q9NUE0
HAVGQSEIVILLQCL	ZFYVE9	971	O95405
VFIGHLCLADLAVAL	AVPR2	76	P30518
RLATFCHLTVLLAGQ	CX3CL1	11	P78423
IIHRDLKCDNIFITG	WNK3	271	Q9BYP7
LFLGRRACIIHGVLQ	LMF1	281	Q96S06
RACIIHGVLQILFQA	LMF1	286	Q96S06
LVCHQIRYLGLLENV	MYO1B	611	O43795
LVAGILHLGNISFCE	MYO1F	276	O00160
AHALVFGILLTCRLL	TMEM35A	116	Q53FP2
ELVELLARHCYVQLG	MYO7B	1326	Q6PIF6
LQLCDLLSGLRVHGV	GRIN2D	101	O15399