Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionlow-density lipoprotein particle receptor activity

LRP1 LRP2 LRP1B

1.96e-0516673GO:0005041
GeneOntologyMolecularFunctionlipoprotein particle receptor activity

LRP1 LRP2 LRP1B

4.60e-0521673GO:0030228
DomainLdl_recept_a

LRP1 LRP2 LRP4 TMPRSS4 CORIN LRP1B SSPOP

2.51e-1045687PF00057
Domain-

LRP1 LRP2 LRP4 TMPRSS4 CORIN LRP1B SSPOP

2.95e-10466874.10.400.10
DomainLDLRA_1

LRP1 LRP2 LRP4 TMPRSS4 CORIN LRP1B SSPOP

4.04e-1048687PS01209
DomainLDLRA_2

LRP1 LRP2 LRP4 TMPRSS4 CORIN LRP1B SSPOP

4.70e-1049687PS50068
DomainLDrepeatLR_classA_rpt

LRP1 LRP2 LRP4 TMPRSS4 CORIN LRP1B SSPOP

4.70e-1049687IPR002172
DomainLDLa

LRP1 LRP2 LRP4 TMPRSS4 CORIN LRP1B SSPOP

4.70e-1049687SM00192
DomainTIL_dom

MUC19 LRP2 MUC5B TECTA SSPOP

1.07e-0914685IPR002919
DomainLDLR_class-A_CS

LRP1 LRP2 LRP4 CORIN LRP1B SSPOP

6.47e-0940686IPR023415
DomainTIL

MUC19 MUC5B TECTA SSPOP

7.78e-0812684PF01826
DomainC8

MUC19 MUC5B TECTA SSPOP

7.78e-0812684PF08742
DomainUnchr_dom_Cys-rich

MUC19 MUC5B TECTA SSPOP

1.12e-0713684IPR014853
DomainC8

MUC19 MUC5B TECTA SSPOP

1.12e-0713684SM00832
DomainLdl_recept_b

LRP1 LRP2 LRP4 LRP1B

1.56e-0714684PF00058
DomainLDLRB

LRP1 LRP2 LRP4 LRP1B

1.56e-0714684PS51120
DomainLY

LRP1 LRP2 LRP4 LRP1B

2.13e-0715684SM00135
DomainLDLR_classB_rpt

LRP1 LRP2 LRP4 LRP1B

2.13e-0715684IPR000033
DomainVWD

MUC19 MUC5B TECTA SSPOP

2.83e-0716684SM00216
DomainVWF_type-D

MUC19 MUC5B TECTA SSPOP

2.83e-0716684IPR001846
DomainVWFD

MUC19 MUC5B TECTA SSPOP

2.83e-0716684PS51233
DomainVWD

MUC19 MUC5B TECTA SSPOP

2.83e-0716684PF00094
DomainEGF

SLIT2 HGFAC LRP1 LRP2 LRP4 TECTA LRP1B

3.71e-07126687PF00008
DomainCTCK_1

SLIT2 MUC19 MUC5B SSPOP

4.73e-0718684PS01185
DomainVWC_out

MUC19 MUC5B TECTA SSPOP

5.98e-0719684SM00215
DomainCys_knot_C

SLIT2 MUC19 MUC5B SSPOP

1.92e-0625684IPR006207
DomainCTCK_2

SLIT2 MUC19 MUC5B SSPOP

1.92e-0625684PS01225
DomaincEGF

LRP1 LRP2 LRP4 LRP1B

2.26e-0626684IPR026823
DomaincEGF

LRP1 LRP2 LRP4 LRP1B

2.26e-0626684PF12662
DomainVWC

MUC19 MUC5B TECTA SSPOP

1.08e-0538684SM00214
DomainVWFC_2

MUC19 MUC5B TECTA SSPOP

1.08e-0538684PS50184
Domain-

LRP1 LRP2 LRP4 LRP1B

1.20e-05396842.120.10.30
DomainDUF5050

LRP1 LRP1B

1.31e-052682IPR032485
DomainDUF5050

LRP1 LRP1B

1.31e-052682PF16472
DomainVWF_dom

MUC19 MUC5B TECTA SSPOP

1.62e-0542684IPR001007
DomainEGF_3

SLIT2 HGFAC LRP1 LRP2 LRP4 LRP1B SSPOP

2.31e-05235687PS50026
DomainEGF

SLIT2 HGFAC LRP1 LRP2 LRP4 TECTA LRP1B

2.31e-05235687SM00181
Domain6-blade_b-propeller_TolB-like

LRP1 LRP2 LRP4 LRP1B

2.34e-0546684IPR011042
DomainEGF_Ca-bd_CS

SLIT2 LRP1 LRP2 LRP4 LRP1B

2.74e-0597685IPR018097
DomainEGF_CA

SLIT2 LRP1 LRP2 LRP4 LRP1B

3.02e-0599685PS01187
DomainASX_HYDROXYL

SLIT2 LRP1 LRP2 LRP4 LRP1B

3.17e-05100685PS00010
DomainEGF-like_dom

SLIT2 HGFAC LRP1 LRP2 LRP4 TECTA LRP1B

3.34e-05249687IPR000742
DomainEGF_1

SLIT2 HGFAC LRP1 LRP2 LRP4 LRP1B SSPOP

3.88e-05255687PS00022
DomainEGF-type_Asp/Asn_hydroxyl_site

SLIT2 LRP1 LRP2 LRP4 LRP1B

4.20e-05106685IPR000152
DomainEGF_2

SLIT2 HGFAC LRP1 LRP2 LRP4 LRP1B SSPOP

4.96e-05265687PS01186
DomainCT

SLIT2 MUC19 MUC5B

6.76e-0522683SM00041
DomainEGF_CA

SLIT2 LRP1 LRP2 LRP4 LRP1B

8.22e-05122685SM00179
DomainEGF-like_Ca-bd_dom

SLIT2 LRP1 LRP2 LRP4 LRP1B

8.88e-05124685IPR001881
DomainSRCR_2

TMPRSS4 CORIN

2.71e-047682PF15494
DomainEGF_CA

LRP1 LRP2 LRP4 LRP1B

2.73e-0486684PF07645
DomainEGF-like_CS

SLIT2 HGFAC LRP1 LRP2 LRP4 LRP1B

3.73e-04261686IPR013032
Domain-

PIKFYVE CCT8L2

7.03e-04116823.30.260.10
DomainTCP-1-like_intermed

PIKFYVE CCT8L2

7.03e-0411682IPR027410
DomainWWE

PARP12 ZC3HAV1

8.42e-0412682PS50918
DomainWWE

PARP12 ZC3HAV1

8.42e-0412682PF02825
DomainWWE-dom

PARP12 ZC3HAV1

8.42e-0412682IPR004170
DomainCpn60/TCP-1

PIKFYVE CCT8L2

1.33e-0315682IPR002423
DomainCpn60_TCP1

PIKFYVE CCT8L2

1.33e-0315682PF00118
Domain-

PIKFYVE CCT8L2

1.33e-03156823.50.7.10
DomainGroEL-like_apical_dom

PIKFYVE CCT8L2

1.33e-0315682IPR027409
DomainPoly(ADP-ribose)pol_cat_dom

PARP12 ZC3HAV1

1.71e-0317682IPR012317
DomainPARP_CATALYTIC

PARP12 ZC3HAV1

1.71e-0317682PS51059
DomainPARP

PARP12 ZC3HAV1

1.71e-0317682PF00644
Domain-

PARP12 ZC3HAV1

1.71e-03176823.90.228.10
DomainGrowth_fac_rcpt_

LRP1 LRP2 LRP4 LRP1B

2.52e-03156684IPR009030
DomainWGR_domain

PARP12 ZC3HAV1

3.42e-0324682IPR008893
DomainSR

TMPRSS4 CORIN

3.71e-0325682SM00202
DomainSRCR_1

TMPRSS4 CORIN

4.01e-0326682PS00420
DomainSRCR_2

TMPRSS4 CORIN

4.01e-0326682PS50287
Pubmed

LRP2 mediates folate uptake in the developing neural tube.

LRP1 LRP2 LRP4 LRP1B

4.36e-091168424639464
Pubmed

Interaction of the apolipoprotein E receptors low density lipoprotein receptor-related protein and sorLA/LR11.

LRP1 LRP2 LRP4

7.13e-08568319047013
Pubmed

MESD is essential for apical localization of megalin/LRP2 in the visceral endoderm.

LRP1 LRP2 LRP4 LRP1B

7.80e-082168421337463
Pubmed

A dual-activity topoisomerase complex regulates mRNA translation and turnover.

PIKFYVE SLC6A8 TRAF4 ABCA2 PIK3C2B PEX6 LRP4 NLRC5 BTAF1 FAAP100 TRAK1 BAHCC1

1.41e-061105681235748872
Pubmed

Normal development and fertility of knockout mice lacking the tumor suppressor gene LRP1b suggest functional compensation by LRP1.

LRP1 LRP2 LRP1B

2.56e-061468315082773
Pubmed

Regulated inositol-requiring protein 1-dependent decay as a mechanism of corin RNA and protein deficiency in advanced human systolic heart failure.

ERN1 CORIN

3.77e-06268225516437
Pubmed

Striking differences of LDL receptor-related protein 1B expression in mouse and human.

LRP1 LRP1B

3.77e-06268215963947
Pubmed

Endocytic Protein Defects in the Neural Crest Cell Lineage and Its Pathway Are Associated with Congenital Heart Defects.

LRP1 LRP2

3.77e-06268234445520
Pubmed

Endocytosis provides a major alternative pathway for lysosomal biogenesis in kidney proximal tubular cells.

CLCN5 LRP2

3.77e-06268217369355
Pubmed

Protein-protein interactions between large proteins: two-hybrid screening using a functionally classified library composed of long cDNAs.

ABCA2 LRP4 ZNFX1 SSPOP BAHCC1

5.83e-0613068512421765
Pubmed

Short-term functional adaptation of aquaporin-1 surface expression in the proximal tubule, a component of glomerulotubular balance.

CLCN5 LRP2

1.13e-05368225270072
Pubmed

Loss of chloride channel ClC-5 impairs endocytosis by defective trafficking of megalin and cubilin in kidney proximal tubules.

CLCN5 LRP2

1.13e-05368212815097
Pubmed

Meta-analysis of 375,000 individuals identifies 38 susceptibility loci for migraine.

LRP1 PLCE1

1.13e-05368227322543
Pubmed

Identification and characterization of human TIPARP gene within the CCNL amplicon at human chromosome 3q25.31.

PARP12 ZC3HAV1

1.13e-05368212851707
Pubmed

Human parietal epithelial cells (PECs) and proteinuria in lupus nephritis: a role for ClC-5, megalin, and cubilin?

CLCN5 LRP2

1.13e-05368237594671
Pubmed

Apolipoprotein M modulates erythrocyte efflux and tubular reabsorption of sphingosine-1-phosphate.

CLCN5 LRP2

2.25e-05468224950692
Pubmed

Disabled-2 is essential for endodermal cell positioning and structure formation during mouse embryogenesis.

LRP1 LRP2

2.25e-05468212413896
Pubmed

Identification of the low density lipoprotein receptor-related protein (LRP) as an endocytic receptor for thrombospondin-1.

LRP1 LRP2

2.25e-0546827775583
Pubmed

Role of apolipoprotein E receptors in regulating the differential in vivo neurotrophic effects of apolipoprotein E.

LRP1 LRP2

2.25e-05468211421580
Pubmed

A novel renal carbonic anhydrase type III plays a role in proximal tubule dysfunction.

CLCN5 LRP2

2.25e-05468218322545
Pubmed

Ectodomains of the LDL receptor-related proteins LRP1b and LRP4 have anchorage independent functions in vivo.

LRP4 LRP1B

3.75e-05568220383322
Pubmed

ApoER2 is endocytosed by a clathrin-mediated process involving the adaptor protein Dab2 independent of its Rafts' association.

LRP1 LRP2

3.75e-05568216101684
Pubmed

Interaction of coagulation factor VIII with members of the low-density lipoprotein receptor family follows common mechanism and involves consensus residues within the A2 binding site 484-509.

LRP1 LRP2

3.75e-05568218685438
Pubmed

Identifications of novel host cell factors that interact with the receptor-binding domain of the SARS-CoV-2 spike protein.

ARHGEF1 RECQL4 PEX6 ZNFX1 BTAF1 PARP12 PLCE1 ZC3HAV1

3.93e-0565068838777146
Pubmed

Expression of Muc19/Smgc gene products during murine sublingual gland development: cytodifferentiation and maturation of salivary mucous cells.

MUC19 MUC5B

5.62e-05668219110483
Pubmed

Interaction of cytosolic adaptor proteins with neuronal apolipoprotein E receptors and the amyloid precursor protein.

LRP1 LRP2

5.62e-0566829837937
Pubmed

A novel interplay between the Fanconi anemia core complex and ATR-ATRIP kinase during DNA cross-link repair.

ATRIP FAAP100

5.62e-05668223723247
Pubmed

The PX-domain protein SNX17 interacts with members of the LDL receptor family and modulates endocytosis of the LDL receptor.

LRP1 LRP2

7.86e-05768212169628
Pubmed

Expression, functional, and structural analysis of proteins critical for otoconia development.

TECTA OC90

1.05e-04868220803598
Pubmed

Chromosomal organization of candidate genes involved in cholesterol gallstone formation: a murine gallstone map.

LRP1 LRP2 MUC5B

1.09e-044768311208732
Pubmed

APP interacts with LRP4 and agrin to coordinate the development of the neuromuscular junction in mice.

LRP1 LRP4

1.34e-04968223986861
Pubmed

LDL receptor-related protein as a component of the midkine receptor.

LRP1 LRP2

1.34e-04968210772929
Pubmed

Establishment and Dysfunction of the Blood-Brain Barrier.

ABCA2 LRP1 LRP2

1.48e-045268326590417
Pubmed

PI(5)P regulates autophagosome biogenesis.

PIKFYVE ZFYVE1

1.68e-041068225578879
Pubmed

Abnormal development of the apical ectodermal ridge and polysyndactyly in Megf7-deficient mice.

LRP1 LRP4

2.90e-041368216207730
Pubmed

Stage-specific association of apolipoprotein A-I and E in developing mouse retina.

LRP1 LRP2

3.38e-041468217389516
Pubmed

Local anesthetics impair the growth and self-renewal of glioblastoma stem cells by inhibiting ZDHHC15-mediated GP130 palmitoylation.

LRP1 LRP2 SSPOP

3.71e-047168333541421
Pubmed

Extensive proteomic screening identifies the obesity-related NYGGF4 protein as a novel LRP1-interactor, showing reduced expression in early Alzheimer's disease.

LRP1 LRP4

3.89e-041568220205790
Pubmed

Genetic predictors of fibrin D-dimer levels in healthy adults.

LRP4 NME7

4.44e-041668221502573
Pubmed

Family-wide analysis of poly(ADP-ribose) polymerase activity.

PARP12 ZC3HAV1

4.44e-041668225043379
Pubmed

Mammalian Otolin: a multimeric glycoprotein specific to the inner ear that interacts with otoconial matrix protein Otoconin-90 and Cerebellin-1.

TECTA OC90

5.03e-041768220856818
Pubmed

Mucin gene expression in human laryngeal epithelia: effect of laryngopharyngeal reflux.

MUC19 MUC5B

5.65e-041868218834073
Pubmed

Interactions of the low density lipoprotein receptor gene family with cytosolic adaptor and scaffold proteins suggest diverse biological functions in cellular communication and signal transduction.

LRP1 LRP2

5.65e-041868210827173
Pubmed

Counteractive and cooperative actions of muscle β-catenin and CaV1.1 during early neuromuscular synapse formation.

SLIT2 LRP4

6.30e-041968235340430
Pubmed

Meta-analysis of genome-wide association studies identifies novel loci that influence cupping and the glaucomatous process.

EXOC2 PLCE1

8.48e-042268225241763
Pubmed

Characterization of 458 single nucleotide polymorphisms of disease candidate genes in the Korean population.

LRP2 MUC5B

8.48e-042268212768436
Pubmed

Genome-wide Identification of Foxf2 Target Genes in Palate Development.

CORIN EXOC2

9.28e-042368232040930
Pubmed

Cis-Repression of Foxq1 Expression Affects Foxf2-Mediated Gene Expression in Palate Development.

CORIN EXOC2

9.28e-042368233898467
Pubmed

A deep proteomics perspective on CRM1-mediated nuclear export and nucleocytoplasmic partitioning.

WDR74 PIK3C2B ARHGEF1 ZNFX1 ZFYVE1 PARP12 TRAK1 ZC3HAV1

9.29e-04103868826673895
Pubmed

Global genetic analysis in mice unveils central role for cilia in congenital heart disease.

SLIT2 LRP1 LRP2

1.01e-0310068325807483
Pubmed

The Interleukin-2-mTORc1 Kinase Axis Defines the Signaling, Differentiation, and Metabolism of T Helper 1 and Follicular B Helper T Cells.

ERN1 PIK3C2B ARHGEF39 AGAP2

1.04e-0322768426410627
Pubmed

Structural basis for endosomal trafficking of diverse transmembrane cargos by PX-FERM proteins.

LRP1 LRP2 LRP1B

1.04e-0310168323382219
Pubmed

Blood-Brain Barrier: From Physiology to Disease and Back.

ABCA2 LRP1 LRP2

1.16e-0310568330280653
Pubmed

Retinoic acid deficiency impairs the vestibular function.

TECTA OC90

1.19e-032668223536097
Pubmed

Proteomic profiling of VCP substrates links VCP to K6-linked ubiquitylation and c-Myc function.

STARD13 WDR74 ARHGEF1 RECQL4 MIF EXOC2 NME7 PARP12 ZC3HAV1

1.24e-03135368929467282
Pubmed

Genetic link between renal birth defects and congenital heart disease.

SLIT2 LRP2

1.38e-032868227002738
Pubmed

Analysis of lipid pathway genes indicates association of sequence variation near SREBF1/TOM1L2/ATPAF2 with dementia risk.

ABCA2 LRP1

1.48e-032968220167577
Pubmed

Lmx1a and lmx1b function cooperatively to regulate proliferation, specification, and differentiation of midbrain dopaminergic progenitors.

SLIT2 CORIN

1.58e-033068221880902
Pubmed

A genome-wide association study of behavioral disinhibition.

STARD13 GLIS1

1.58e-033068223942779
Pubmed

Gene-smoking interactions identify several novel blood pressure loci in the Framingham Heart Study.

LRP2 LRP1B

1.80e-033268225189868
GeneFamilyLow density lipoprotein receptors

LRP1 LRP2 LRP4 LRP1B

3.34e-0813494634
GeneFamilyZinc fingers|Zinc fingers PARP-type|Poly(ADP-ribose) polymerases

PARP12 ZC3HAV1

9.53e-0417492684
GeneFamilyCD molecules|Mucins

MUC19 MUC5B

1.46e-0321492648
GeneFamilyZinc fingers FYVE-type|Pleckstrin homology domain containing|Rho guanine nucleotide exchange factors

PIKFYVE ZFYVE1

3.18e-033149281
GeneFamilyZinc fingers CCCH-type

PARP12 ZC3HAV1

4.04e-033549273
CoexpressionGSE29618_BCELL_VS_PDC_DN

TRAF4 ERN1 SERPINF1 BTAF1 MILR1 BAHCC1

1.28e-05198686M4942
CoexpressionLIM_MAMMARY_STEM_CELL_UP

BNC1 SLC6A8 SLIT2 HGFAC SERPINF1 LRP1 LRP4 ASPHD2

3.32e-05479688M2573
CoexpressionLIM_MAMMARY_STEM_CELL_UP

BNC1 SLC6A8 SLIT2 HGFAC SERPINF1 LRP1 LRP4 ASPHD2

3.52e-05483688MM1082
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic-thymocyte|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ADAMTS16 LRP2 MUC5B CSMD3 LRP1B SSPOP PLCE1

1.34e-081846872cbed6462fea2622871bb7e49b0df3d984239281
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ADAMTS16 LRP2 MUC5B CSMD3 LRP1B SSPOP PLCE1

1.34e-08184687ea7a7e2bac46d4d2c31a5d576b38a032b5335062
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic-proliferating_thymocyte;_DN_to_DP_transition,_dividing_(some_are_Cd8+/_Cd4+,_some_undergoing_VDJ_recombination)|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ADAMTS16 LRP2 MUC5B CSMD3 LRP1B SSPOP PLCE1

1.34e-081846872b19a8c5f823e00812908b23e66bb4e563278aff
ToppCellfacs-Marrow-B-cells-24m-Lymphocytic-precursor_B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MUC19 LRP2 MUC5B TECTA LRP1B

4.65e-06160685c381ec6be8cf887861cc18f831a20db42f953fe1
ToppCellfacs-Marrow-B-cells-24m-Lymphocytic-pre_B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MUC19 LRP2 MUC5B TECTA LRP1B

4.65e-0616068525c8f3d2a6d14ff0ca0b965fce89d3ff22f40585
ToppCellTransplant_Alveoli_and_parenchyma-Epithelial-Basal_2|Epithelial / Tissue, Lineage and Cell class of Lung Cells from 10X

ATRIP TNFSF8 SERPINF1 TMPRSS4 KEL

5.09e-06163685f21951e63188eb0c04675a8f81a0da495c26c007
ToppCelldroplet-Fat-Mat-18m-Lymphocytic-lymphocyte|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TRAF4 TNFSF8 DUSP4 NLRC5 AGAP2

6.61e-06172685226de1a5d4a360d3ae01b0235fea19521ec623a0
ToppCellfacs-Trachea-18m-Mesenchymal-fibroblast-fibroblast_of_trachea-|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

MRAP KEL TECTA CSMD3 AGAP2

9.66e-06186685bdc87e4631a8ea73e262e541aa84a28f24c94b00
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Immune-Lymphocytic_T/NK-T_Cell-|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

ERN1 TNFSF8 ARHGEF1 NLRC5 ZC3HAV1

1.10e-051916851a2d5fec2bea96da2154b0aed252f1bb35102f6e
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Immune-Lymphocytic_T/NK-T_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

ERN1 TNFSF8 ARHGEF1 NLRC5 ZC3HAV1

1.10e-05191685326b4541069efedc8ab409f85bb11f77346dda90
ToppCellLA|World / Chamber and Cluster_Paper

SLIT2 SERPINF1 LRP1 LRP2 LRP1B

1.15e-05193685d4bf89437216baf489ea0239136dcedf3b6714af
ToppCellMild|World / Disease group and Cell class

ATRIP ARHGEF1 NLRC5 ZNFX1 PARP12

1.24e-051966855e4ed4a5a437cfa002b92775992a791e27aa4c27
ToppCellMild-CD8+_T_activated|World / Disease group and Cell class

ATRIP ARHGEF1 NLRC5 ZNFX1 PARP12

1.24e-0519668579632190e44fcef9d7c11d9b9e37f2ebf0e6e255
ToppCellfrontal_cortex-Neuronal-GABAergic_neuron-Pvalb-Pvalb_Gabrg1|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

SLIT2 SERPINF1 ADAMTS16 CORIN

3.22e-051186843f0a304ef9c9e5ba047fc09f4372590eed624328
ToppCellfacs-Skin-Anagen-24m-Epithelial-nan|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MIF LRP4 NLRC5 TMPRSS4

6.09e-05139684da8874d441b8e69c94bad771635f378ddafb49fe
ToppCellprimary_visual_cortex-Neuronal-GABAergic_neuron-Pvalb-Pvalb_Gabrg1|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

SLIT2 SERPINF1 ADAMTS16 CORIN

6.27e-051406842c44e8cc5190226049be7ebc465d685393e701c4
ToppCellPosterior_cortex-Neuronal-Excitatory-eN2(Slc17a7_Slc17a6)-Tshz2-Excitatory_Neuron.Slc17a7-Slc17a6.Tshz2-Rasd1_(Presubiculum,_Col5a2+)-|Posterior_cortex / BrainAtlas - Mouse McCarroll V32

C6orf15 TECTA SYCE1

7.75e-0554683e40294b708b06f7eee1c099fc67f53a3bb76e306
ToppCellPosterior_cortex-Neuronal-Excitatory-eN2(Slc17a7_Slc17a6)-Tshz2-Excitatory_Neuron.Slc17a7-Slc17a6.Tshz2-Rasd1_(Presubiculum,_Col5a2+)|Posterior_cortex / BrainAtlas - Mouse McCarroll V32

C6orf15 TECTA SYCE1

7.75e-0554683a1b3f38a90ca975a3e9c4dadfe3cd4e701a6cb1e
ToppCell3'_v3-blood-Lymphocytic_T_CD4-Trm_Th1/Th17|blood / Manually curated celltypes from each tissue

TRAF4 ERN1 DUSP4 NME7

8.84e-05153684d09bc7322b59f613d66673359ee6af1aea99ce87
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Collecting_tubule_epithelial_cell-kidney_connecting_tubule_epithelial_cell-Connecting_Tubule_Cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

SLIT2 ADAMTS16 KEL LRP1B

8.84e-051536849b6675ace8a83c8d446b722301d0ec4e6840f3fc
ToppCell343B-Epithelial_cells-Epithelial-H_(AT1)-|343B / Donor, Lineage, Cell class and subclass (all cells)

SERPINF1 TMPRSS4 KEL MUC5B

9.77e-05157684dd08dc19d434e94a194076c462ee273c682abf55
ToppCell343B-Epithelial_cells-Epithelial-H_(AT1)|343B / Donor, Lineage, Cell class and subclass (all cells)

SERPINF1 TMPRSS4 KEL MUC5B

9.77e-0515768470fd6c46db4250c7de5c4686a9500689402737f6
ToppCell390C-Myeloid-Macrophage-SPP1+_Macrophage_2|Macrophage / Donor, Lineage, Cell class and subclass (all cells)

TRAF4 DUSP4 NLRC5 ZC3HAV1

1.05e-041606848aaf6ac4f33ea291387fdbf9ff1a91d559391774
ToppCellClub_cells-HP_01|World / lung cells shred on cell class, cell subclass, sample id

DUSP4 SERPINF1 TMPRSS4 MUC5B

1.08e-04161684bd08a23b415617f6e8748ed2668d578a860ecf91
ToppCellPBMC_fresh-frozen-Severe-critical_progression_d12-22-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD4_c04-ANXA2|Severe-critical_progression_d12-22 / Compartment, severity and other cell annotations on 10x 3' data (130k)

TRAF4 RECQL4 TRIM34 TRAK1

1.13e-04163684ce07bc424ef99c547588b07f5c8b39ff0773ca9b
ToppCell343B-Lymphocytic-CD4_T-cell-CD4+_Effector_T_cell-1|343B / Donor, Lineage, Cell class and subclass (all cells)

TNFSF8 DUSP4 AGAP2 ZC3HAV1

1.13e-0416368493bc67a13267c858cabc81eafe1c9b966d872a9e
ToppCellfacs-Brain_Myeloid-Hippocampus-24m-Myeloid|Brain_Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HGFAC SERPINF1 LRP1 CSMD3

1.24e-041676847f3224af9b30082b927a822b91f96e0c88151b4e
ToppCellfacs-Brain_Myeloid-Hippocampus-24m-Myeloid-nan|Brain_Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HGFAC SERPINF1 LRP1 CSMD3

1.24e-04167684a21a2b301d0a3d7a41e605f7a3c37548962a331d
ToppCellfacs-Brain_Myeloid-Hippocampus-24m|Brain_Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HGFAC SERPINF1 LRP1 CSMD3

1.24e-041676840e746483773bde6582874a33591ab2a578d724eb
ToppCellfacs-Large_Intestine-Distal-3m-Epithelial-enterocyte_of_epithelium_of_large_intestine|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SLC6A8 NME7 PARP12 TRAK1

1.27e-0416868403896466698a79f7f1ad862cb7e05585260e2a5a
ToppCellPND28-Immune-Immune_Myeloid-Monocytic-Macrophage-iMON-iMON_prolif|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

ERN1 SLC35C1 MILR1 PARP12

1.27e-0416868427cdf5cfa1d906868cfd60fdfab3cd51f3b3602f
ToppCellCOVID-19-Heart-Adipocyte|Heart / Disease (COVID-19 only), tissue and cell type

CLCN5 MRAP DUSP4 GLIS1

1.30e-04169684bd39f85b48207955f80ca120a11e15a0124117b9
ToppCelldroplet-Marrow-BM-30m|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TNFSF8 C6orf15 NLRC5 KEL

1.30e-041696848e7a30eb546fc6fa184ebb76f54b74b278005a84
ToppCellfacs-Brain_Myeloid-Hippocampus-24m-Myeloid-microglial_cell|Brain_Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HGFAC SERPINF1 LRP1 CSMD3

1.33e-04170684b4f2c05db2c2591561fd42febc72eed3b5e8f9fb
ToppCellmetastatic_Lymph_Node-Myeloid_cells-pDCs|metastatic_Lymph_Node / Location, Cell class and cell subclass

TRAF4 CLCN5 ERN1 SERPINF1

1.36e-041716841f8e66073088fc1969782e443bf00f8c1877ea91
ToppCell3'-Broncho-tracheal-Mesenchymal-Fibroblastic-fibroblastic_type_1-Adventitial_fibroblasts-|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

SLIT2 CCT8L2 LRP1 TECTA

1.39e-04172684e37c0b5b547a7345179ab258dd2141fec7064c17
ToppCell(0)_Normal/No_Treatment-(4)_COL2.3+_osteoblasts|(0)_Normal/No_Treatment / Stress and Cell class

SLIT2 SERPINF1 LRP1 LRP4

1.42e-04173684c2a0f674681836b5a868c13f67caa7d555ef6519
ToppCell5'-Adult-LymphNode-Hematopoietic-T_cells-TRGV2_gdT|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

KLF11 TNFSF8 RECQL4 GLIS1

1.42e-0417368479d11f94a8f6a420c18c2fef0da77e9af3204765
ToppCellfacs-Diaphragm-Limb_Muscle-24m-Mesenchymal|Diaphragm / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SERPINF1 LRP2 CSMD3 LRP1B

1.42e-0417368466f37c1437705734b20601656fa4aa1d92ca30be
ToppCellfacs-Diaphragm-Limb_Muscle-24m-Mesenchymal-nan|Diaphragm / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SERPINF1 LRP2 CSMD3 LRP1B

1.42e-04173684649b08a409095592cccf31883be69c754411280d
ToppCellASK428-Immune-B_cell|ASK428 / Donor, Lineage and Cell class of Lung cells from Dropseq

PIKFYVE CLCN5 PIK3C2B ARHGEF39

1.45e-04174684b5a7a612a515736cf3489afd0f6ad2054d54526f
ToppCellASK428-Immune-B_cell|Immune / Donor, Lineage and Cell class of Lung cells from Dropseq

PIKFYVE CLCN5 PIK3C2B ARHGEF39

1.48e-04175684e0979e5795a49b4e5c9b88e7fe6b7bda7a413a6c
ToppCellfacs-Marrow-B-cells-24m|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MUC19 LRP2 CSMD3 LRP1B

1.48e-04175684887e75fc90e59a6394d62f3c048a9cfdf6707725
ToppCellfacs-Heart-RV-18m-Mesenchymal-fibroblast_of_cardiac_tissue|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SERPINF1 LRP1 LRP4 ASPHD2

1.52e-04176684c0a084f7a8645262d61971f094689e02bf15b113
ToppCellfacs-Heart-RV-18m-Mesenchymal-fibroblast_of_cardiac_tissue|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SERPINF1 LRP1 LRP4 ASPHD2

1.52e-04176684cccf9201f6e2da7524b911a5961d3b227edab222
ToppCell343B-Fibroblasts-Fibroblast-A_(Fibroblast_progenitors)-|343B / Donor, Lineage, Cell class and subclass (all cells)

SLIT2 SERPINF1 LRP1 LRP1B

1.52e-041766842e94bbe17c0bb65dc58b4ebc0cb829258bd7373b
ToppCell343B-Fibroblasts-Fibroblast-A_(Fibroblast_progenitors)|343B / Donor, Lineage, Cell class and subclass (all cells)

SLIT2 SERPINF1 LRP1 LRP1B

1.52e-04176684f33ab41d121b59d871ad7d48ca021524a027d2ef
ToppCell3'-Airway_Nasal-Epithelial-Epithelial_transtional-secretory-club_cell-Club_(non-nasal)-Club_(non-nasal)_L.0.4.0.1|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

BNC1 TRIM45 ABCA2 MUC5B

1.55e-04177684a235ff4f37a7622216526191efc4832fb8ed6957
ToppCell(1)_Control_(PBS)-(2)_LEPR+_perivascular_cells_and_VE-Cad+_vascular_cells_(mixed)|(1)_Control_(PBS) / Stress and Cell class

SLIT2 LRP1 LRP4 NLRC5

1.55e-04177684d9e5ac5b8949a77e88e8094079167e4cf2c1bbd1
ToppCell21-Trachea-Epithelial-Submucosal_gland|Trachea / Age, Tissue, Lineage and Cell class

WDR74 DUSP4 C6orf15 MUC5B

1.58e-041786843e406e38eea0d38dc25edecf703c4c89ec6a28e0
ToppCellfacs-Large_Intestine-Distal-3m-Epithelial-nan|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SLC6A8 HGFAC PIK3C2B NME7

1.65e-04180684a0faed4cf23f6d5e6e8f6b0284cea8a5bd0680a0
ToppCellfacs-Pancreas-Exocrine-24m|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MUC19 LRP2 CSMD3 LRP1B

1.65e-0418068472310baeed848f2c483ae986cd73d2fb2cca7feb
ToppCellwk_20-22-Hematologic-Myeloid-pDC|wk_20-22 / Celltypes from embryonic and fetal-stage human lung

TRAF4 CLCN5 ERN1 SERPINF1

1.69e-0418168460607c5ff6d5b1cb416adc034491dca31c41e988
ToppCellRA-17._Lymphocyte|RA / Chamber and Cluster_Paper

ERN1 TNFSF8 NLRC5 ZC3HAV1

1.72e-04182684257a7847917b6ea1d60608183d90300bfd028758
ToppCell5'-Parenchyma_lung-Mesenchymal-Fibroblastic-fibroblastic_type_1-Adventitial_fibroblasts-Adventitial_fibroblasts_L.2.1.2.2|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

SERPINF1 ADAMTS16 LRP4 TECTA

1.76e-0418368406a68fa2be36448064f4668be24a5b85ad85c6e8
ToppCellControl-Epithelial_cells-Airway_mucous|Control / group, cell type (main and fine annotations)

SLC6A8 PIK3C2B TMPRSS4 MUC5B

1.76e-0418368415d24a4fb1ffe6cbafbd54fcd7dde9ddcfbe03b2
ToppCellCalu_3-infected|Calu_3 / Cell line, Condition and Strain

NLRC5 ZNFX1 PARP12 ZC3HAV1

1.76e-041836848f7f5000645f24f20a8d7700c4df1f8953a1780b
ToppCellfacs-Heart-RA-18m-Mesenchymal-valve_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MRAP DUSP4 AGAP2 PLCE1

1.76e-041836840f02136359787bd78146617990968baa47a65d86
ToppCellfacs-Heart-RA-18m-Mesenchymal-valve_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MRAP DUSP4 AGAP2 PLCE1

1.76e-041836842f0dcc65ad4d90ef946919b4462280fdd20c5ea0
ToppCellRA-17._Lymphocyte|World / Chamber and Cluster_Paper

ERN1 TNFSF8 NLRC5 ZC3HAV1

1.76e-041836846397f684a50346fc42cccb5afbe10350f4b2d9b0
ToppCellwk_08-11-Epithelial-Proximal_epithelial-Proximal_secretory_progenitors|wk_08-11 / Celltypes from embryonic and fetal-stage human lung

DUSP4 SERPINF1 TMPRSS4 MUC5B

1.80e-04184684fcb5dd4fb3fa79f3b6029fad32a474cacde35a3b
ToppCellBac-SEP-Myeloid-pDC|Bac-SEP / Disease, Lineage and Cell Type

TRAF4 ERN1 SERPINF1 MILR1

1.83e-041856843de50b2042f22b0fb62ff12c76d85cc67649a0bd
ToppCell5'-Airway_Nasal-Epithelial-Airway_epithelium-respiratory_basal_cell-Suprabasal-Suprabasal_L.0.0.1.0|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

BNC1 SLC6A8 TMPRSS4 KEL

1.83e-04185684e0172e0ab0f1d7151a3c3c63bb7c84d6bda92035
ToppCell(5)_Epithelial_cells-(5)_Glands_duct|(5)_Epithelial_cells / Oesophagus cell shreds on cell class (v1) and cell subclass (v1)

DUSP4 C6orf15 TMPRSS4 MUC5B

1.87e-04186684219b1aeca17503244fabbb780bca58f22c7c0f27
ToppCellMild-Lymphoid-pDC|Mild / Condition, Lineage, Cell class and cell subclass

TRAF4 CLCN5 ERN1 SERPINF1

1.87e-041866847fa82972c726025d6402e5eb7bf0db3b699eba4c
ToppCellSmart-seq2-blood_(Smart-seq2)-myeloid-myeloid_monocytic-classical_monocyte|blood_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

LRP1 MUC19 CSMD3 LRP1B

1.87e-0418668423b8d51d20b05795a73892d3e20e0f9b6a207820
ToppCellMild-Lymphoid-pDC-|Mild / Condition, Lineage, Cell class and cell subclass

TRAF4 CLCN5 ERN1 SERPINF1

1.87e-041866841d05e73ae2ec0cc27f79e4fa40d6b21790059f80
ToppCellfacs-Lung-18m-Mesenchymal-fibroblast-adventitial_fibroblast-adventitial_fibroblast_l25-31|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

MRAP SERPINF1 ASPHD2 PLCE1

1.91e-04187684fa8f221b4c2df61eadaa9c77e4cf45848b00330b
ToppCellCV-Severe-3|Severe / Virus stimulation, Condition and Cluster

SLC6A8 DUSP4 RECQL4 LRP1

1.91e-0418768468cb43a73945f5e252530da25613f6b3f484b4d5
ToppCellMild_COVID-19-Myeloid-pDC|Mild_COVID-19 / Disease group,lineage and cell class （2021.01.30）

TRAF4 CLCN5 ERN1 SERPINF1

1.91e-0418768499c3c4a7b9179dce7982dc6516d561c952abc80e
ToppCell10x5'v1-week_14-16-Myeloid_DC-DC-pDC|week_14-16 / cell types per 3 fetal stages;per 3',per 5'

TRAF4 CLCN5 ERN1 SERPINF1

1.91e-04187684bf64a6ef5062ec9a0f7095e8c97ce66bfc3bf179
ToppCellcontrol-pDC|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

TRAF4 CLCN5 SERPINF1 MILR1

1.91e-04187684c78aee98b32719aa45811b620fc97be1ecf5fd53
ToppCellChildren_(3_yrs)-Immune-T_lymphocyte-D032|Children_(3_yrs) / Lineage, Cell type, age group and donor

ERN1 TNFSF8 NLRC5 ZC3HAV1

1.99e-04189684df30478b288084a1bd48f660409dcc784040897c
ToppCell5'-Parenchyma_lung-Mesenchymal-Fibroblastic-fibroblastic_type_1-Adventitial_fibroblasts-Adventitial_fibroblasts_L.2.1.2.1|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

SLIT2 SERPINF1 ADAMTS16 LRP1

1.99e-04189684d531399749409d614adca13d181830c6e3287508
ToppCellCOVID-19-Epithelial_cells-Tuft-like|COVID-19 / group, cell type (main and fine annotations)

TRAF4 MIF TMPRSS4 MUC5B

1.99e-041896842ffbe79fe3c3f22b1cb4269726b9eb5519be84a7
ToppCellPCW_05-06-Mesenchymal-Mesenchymal_fibroblastic-mes_immature_COL13A1^pos_fibro1_(4)|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung

SLIT2 ADAMTS16 LRP1B PLCE1

2.03e-041906847986586b7c82e91c71102cc8c4d7a689ae63ab4d
ToppCellfacs-Heart-RA-3m-Mesenchymal-valve_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PINLYP MRAP DUSP4 AGAP2

2.03e-04190684bfbdf16d488359d7935a419c4c1823288f39c183
ToppCellfacs-Heart-RA-3m-Mesenchymal-valve_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PINLYP MRAP DUSP4 AGAP2

2.03e-04190684eb1f8bb4d903b08e50c2dc173b06c0c79d8e316e
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Immune-Lymphocytic_T/NK|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

TNFSF8 ARHGEF1 NLRC5 ZC3HAV1

2.03e-04190684b772a5d281fe016f259ddda80d6f33d949dcac2b
ToppCellcellseq-Epithelial-Epithelial_Glandular-SMG_Basal/Duct|cellseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

DUSP4 C6orf15 TMPRSS4 MUC5B

2.07e-0419168430e7cc5f7eadf90ab0900a73fdfe48f9a1adcbfb
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Immune-Lymphocytic_T/NK|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

TNFSF8 DUSP4 NLRC5 ZC3HAV1

2.07e-04191684d9506b88d806aadd4c2b9bf86fe994c47799e7f6
ToppCell(01)_Dendritic_cell|World / immune cells in Peripheral Blood (logTPM normalization)

TRAF4 MRAP SERPINF1 MILR1

2.07e-041916841f4c8078e1a6cd14937c714330af608caced2acf
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Immune-Lymphocytic_T/NK-T_Cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

TNFSF8 DUSP4 NLRC5 ZC3HAV1

2.07e-04191684b42c54308abe1241cc38ddce96b9d38d07983891
ToppCellcellseq-Epithelial-Epithelial_Glandular-SMG_Basal/Duct-SMG_Basal/Duct|cellseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

DUSP4 C6orf15 TMPRSS4 MUC5B

2.07e-0419168441d2f5278f6d5f52a5bdf4f3df70969481c00162
ToppCellCalu_3-infected-SARSCoV2|infected / Cell line, Condition and Strain

NLRC5 ZNFX1 PARP12 ZC3HAV1

2.07e-041916842da876d26f37a00dbdf1ee79d724306e8b20f304
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Immune-Lymphocytic_T/NK-T_Cell-|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

TNFSF8 DUSP4 NLRC5 ZC3HAV1

2.07e-041916849aabbc65430e2233b8f2d3fff9face7807b88b48
ToppCellFetal_29-31_weeks-Immune-T_lymphocyte-D062|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

TNFSF8 NLRC5 AGAP2 ZC3HAV1

2.11e-0419268492f141d5ac462f652f405efa73ac6ef751f40ea3
ToppCell390C-Epithelial_cells-Epithelial-G_(Club-Clara_cells)|Epithelial_cells / Donor, Lineage, Cell class and subclass (all cells)

DUSP4 SERPINF1 TMPRSS4 MUC5B

2.11e-041926845d24bb6c6c17a6b803b241d065b31896a7d86c37
ToppCell10x_3'_v2v3-Non-neoplastic-Lymphoid-CD4/CD8-CD4_INF-G|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

ERN1 ARHGEF1 DUSP4 ZC3HAV1

2.11e-041926841b0138fd0bfdee266325751f8b2d163d91a71bf5
ToppCell390C-Epithelial_cells-Epithelial-G_(Club-Clara_cells)-|Epithelial_cells / Donor, Lineage, Cell class and subclass (all cells)

DUSP4 SERPINF1 TMPRSS4 MUC5B

2.11e-04192684c6795ceba90f1a5d441dff92a737b9c7d28b06b0
ToppCell(7)_Epithelial_cells-(7)_Epithelial-H_(AT1)|(7)_Epithelial_cells / Lung cell shreds - cell class (v4) and cell subclass (v4)

SERPINF1 LRP4 TMPRSS4 KEL

2.11e-041926847a6dd2ae217b8f8e460d47ad128904408299458c
ToppCellBAL-Mild|BAL / Compartment, Disease Groups and Clusters

ATRIP TRIM34 ZNFX1 PARP12

2.11e-041926841a6cbf014d3f7a3fb6f53adab078c4742e7137de
ToppCell5'-GW_trimst-2-SmallIntestine-Mesenchymal-stromal_related|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

SERPINF1 CORIN LRP1B PLCE1

2.16e-04193684f27e2be497745098b5269aa799dd3d5f62d78ba7
ToppCellASK440-Epithelial-Secretory|ASK440 / Donor, Lineage and Cell class of Lung cells from Dropseq

TRAF4 SERPINF1 TMPRSS4 MUC5B

2.16e-0419368450e98d91697c7af6a3de39e52edde6dd2b67b512
ToppCell3'-GW_trimst-1.5-LargeIntestine-Mesenchymal-fibroblastic|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

SERPINF1 ADAMTS16 LRP4 CSMD3

2.16e-0419368468089ba4123e2f9bea9aae0023a844b5a57bfc0e
ToppCellVE-pDC-|VE / Condition, Cell_class and T cell subcluster

TRAF4 CLCN5 SERPINF1 MILR1

2.16e-04193684583724de588fcde3aeda056138c522dc0225a387
ToppCell5'-GW_trimst-2-SmallIntestine-Mesenchymal-stromal_related-ICC|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

SERPINF1 CORIN LRP1B PLCE1

2.16e-041936844ccf984baebbb13ae916727137ce593fda7514a2
ToppCellVE-pDC|VE / Condition, Cell_class and T cell subcluster

TRAF4 CLCN5 SERPINF1 MILR1

2.16e-04193684bb759dc9ef0ec41d655002f59021d62d62d44289
ToppCellChildren_(3_yrs)-Immune-T_lymphocyte-D139|Children_(3_yrs) / Lineage, Cell type, age group and donor

ERN1 TNFSF8 NLRC5 ZC3HAV1

2.20e-041946843d6f2d190dd50804afea299957cc44c2bb756134
ToppCell3'-Parenchyma_lung-Immune_Lymphocytic-Lymphocytic_T/NK-CD4-positive,_alpha-beta_T_cell|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

TNFSF8 ARHGEF1 DUSP4 ZC3HAV1

2.20e-041946841bb5ac162f547de9dd91680df247b49a00920062
Drugtryptophol

ARHGEF1 DUSP4 MIF TECTA

1.14e-0627674CID000010685
Drugmonatepil

LRP1 LRP2 LRP4 LRP1B

1.54e-0629674CID000060810
DrugIvermectin [70288-86-7]; Down 200; 4.6uM; MCF7; HT_HG-U133A

SLC6A8 SLIT2 ABCA2 PIK3C2B SERPINF1 LRP2 TRAK1

1.65e-061946772213_DN
DrugPHA-00816795 [212631-79-3]; Up 200; 10uM; PC3; HT_HG-U133A

SLC6A8 ZNF671 TRAF4 SLC35C1 ZNF576 TRAK1 ZC3HAV1

1.89e-061986777076_UP
Drugmangrove

PIKFYVE ERN1 PIK3C2B LRP1 LRP2 PEX6 LRP4 ZFYVE1 LRP1B

9.02e-06468679CID000000965
DrugDiphemanil methylsulfate [62-97-5]; Down 200; 10.2uM; PC3; HT_HG-U133A

BNC1 ZNF671 SLC35C1 LRP1 BAHCC1 ZC3HAV1

2.43e-051966764591_DN
Diseasesciatic neuropathy (is_implicated_in)

SERPINF1 LRP1

4.91e-055662DOID:11446 (is_implicated_in)
DiseaseT-cell surface glycoprotein CD3 epsilon chain measurement

PIKFYVE NME7

3.78e-0413662EFO_0802114
Diseaseglaucoma

KLHL38 EXOC2 LRP1B PLCE1

4.00e-04154664MONDO_0005041
Diseaseproliferative diabetic retinopathy (is_marker_for)

SLIT2 SERPINF1

5.79e-0416662DOID:13207 (is_marker_for)
Diseasemigraine disorder, endometriosis

EXOC2 LRP1B PLCE1

5.94e-0473663EFO_0001065, MONDO_0005277
Diseasecervical artery dissection

LRP1 PLCE1

6.56e-0417662EFO_1000059
Diseaseoptic disc size measurement

LRP2 EXOC2 LRP1B PLCE1

1.16e-03205664EFO_0004832
DiseaseRenal glomerular disease

CLCN5 PLCE1

1.21e-0323662C0268731
DiseaseGlomerulopathy Assessment

CLCN5 PLCE1

1.21e-0323662C4521256
Diseasemigraine disorder, pulse pressure measurement

LRP1 PLCE1

1.55e-0326662EFO_0005763, MONDO_0005277
DiseaseChild Development Disorders, Specific

SLC6A8 LRP2

1.92e-0329662C0085997
DiseaseChild Development Deviations

SLC6A8 LRP2

1.92e-0329662C0085996
DiseaseD dimer measurement

LRP4 NME7

2.06e-0330662EFO_0004507
DiseaseDevelopmental Disabilities

SLC6A8 LRP2

2.06e-0330662C0008073
Diseasecholesteryl esters to total lipids in large LDL percentage

HGFAC NLRC5

2.20e-0331662EFO_0022249

Protein segments in the cluster

PeptideGeneStartEntry
GAAKCTSALPHLLIC

nan

586

A8MVM7
GACEGRPKHLTSCLL

BAHCC1

271

Q9P281
LCCLHADMLGSLGPK

ARHGEF1

76

Q92888
CNPGYTLHGSSLLKC

CSMD3

1381

Q7Z407
SLPSGLPITCHLCQK

BNC1

921

Q01954
LICGKNASGVLCLPD

BTBD11

371

A6QL63
SQLCADILLQHGCPG

AGAP2

1136

Q99490
SGCLLHQKPSASLAC

ADAMTS16

1161

Q8TE57
CGGLLSLSFPHEKLL

ARHGEF39

296

Q8N4T4
LDDITHSGCLPLGQC

MUC5B

371

Q9HC84
LKTCRNPSGHCLVDL

MUC5B

1176

Q9HC84
LKALPEGACHLSCLQ

ITPRIP

396

Q8IWB1
NGGCSHLCLLAPGKT

LRP1B

3281

Q9NZR2
PGGCSDICLLANSHK

LRP1

486

Q07954
TDLIGLTICGHNCLL

EXOC2

36

Q96KP1
HCGILLDSSGPLASC

MUC19

1006

Q7Z5P9
HLGLHLLKVPCSSLC

PEX6

486

Q13608
LLCTLLGLGCPLHCE

PINLYP

16

A6NC86
TNNGGCSHLCLIKPG

LRP2

3471

P98164
PCALCSLHSIGKIGG

MIF

56

P14174
HTPKCGGQSLCEKLL

OC90

376

Q02509
RAALKDGHSGVPLCC

FAAP100

716

Q0VG06
LSSPCLNGGTCHLIV

HGFAC

246

Q04756
TLFSHLCNGTLLPGC

NLRC5

326

Q86WI3
LEQLCKALGGSCHLG

NLRC5

991

Q86WI3
STGGDSCPFCLKLLL

MILR1

216

Q7Z6M3
CSLSHGGKELCSPLQ

PIK3C2B

656

O00750
SKPGCVGLCAQLHLC

PARP12

81

Q9H0J9
AGSCAPLGLLLVCLH

C6orf15

6

Q6UXA7
CPQHLGCTIKLRGGS

PIKFYVE

831

Q9Y2I7
LLCKGLSALAACCPG

SLC35C1

86

Q96A29
IRCHLGLKTPNGCEL

ASPHD2

291

Q6ICH7
RLCQSLGELCPHLKQ

COG1

616

Q8WTW3
LGELCPHLKQCILGK

COG1

621

Q8WTW3
GKTLQSICILAGDHC

BTAF1

1296

O14981
LLGACSLDCLHPEKH

ERN1

786

O75460
LSLGKEGPLVHVACC

CLCN5

276

P51795
IAIISHGKLKCCGSP

ABCA2

1191

Q9BZC7
SEPSGHICGCVLIAK

CORIN

821

Q9Y5Q5
PCHICGKGFITLSNL

FIZ1

471

Q96SL8
CQPCLHKSGGLLLTD

KLF11

231

O14901
PQLCSHSEGCLLLLL

ATRIP

621

Q8WXE1
HLPEGSLKRCCVLGL

GLIS1

56

Q8NBF1
LSLPFHGCLLDLGTC

C9orf57

86

Q5W0N0
TLGLPSGGKCLLLDC

DUSP4

36

Q13115
TALLLLPCGLLACHN

SLC22A20P

21

A6NK97
CCIVKPHAVSEGLLG

NME7

241

Q9Y5B8
IEPCGSGKSRLTHIC

STARD13

1056

Q9Y3M8
LLTEPLSLDCGHSLC

TRIM34

21

Q9BYJ4
LGNSGKTHCPLCLGL

TRIM45

21

Q9H8W5
LPCGASGLTCTKALA

SSPOP

1056

A2VEC9
TAHGRISVGPCLKQC

PLCE1

431

Q9P212
VSGLPPCLKAACIHS

RECQL4

541

O94761
SHGLNLHLCIQKCLP

MRAP

81

Q8TCY5
SCLLPGLAISGKLCG

CCT8L2

216

Q96SF2
CVPLHLLGCLLRAKG

SLC6A8

571

P48029
LPGLCHGKLIRTNAC

TRAK1

16

Q9UPV9
GYVLNGKSCILPHSC

TECTA

1411

O75443
QCHPSKPLLASCGLD

WDR74

276

Q6RFH5
PLKGGNCSEDLLCIL

TNFSF8

76

P32971
CDICGPILKDTLHLA

ZNF671

166

Q8TAW3
LLLCIGALLGHSSCQ

SERPINF1

6

P36955
HQLCSLCGAEGPSTL

SYCE1

211

Q8N0S2
GPCLSGSLVSLHCLA

TMPRSS4

181

Q9NRS4
GSLVSLHCLACGKSL

TMPRSS4

186

Q9NRS4
LGNKCVHGTCLPINA

SLIT2

1376

O94813
PGHLKDSCNTALVLC

TRAF4

236

Q9BUZ4
TKLLVCGHPCIGLCG

ZNFX1

1541

Q9P2E3
CDLCKGLSGHLPGVR

ZFYVE1

71

Q9HBF4
PCDNLHLCKLNLLGR

ZC3HAV1

81

Q7Z2W4
GNICHLGAPKCTRCL

ZNF576

26

Q9H609
LLPGGCLACDNHALQ

KEL

591

P23276
SLCGTTVPDCKLLLH

KLHL38

261

Q2WGJ6
GALLCAHGLASSPEC

LRP4

11

O75096