Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionRNA polymerase II CTD heptapeptide repeat kinase activity

CDK12 BRD4 CCNK

5.08e-0610713GO:0008353
GeneOntologyMolecularFunctionenzyme regulator activity

NOLC1 PHACTR2 TBC1D10A KALRN PIK3R1 RAPGEF1 ARHGAP17 ARHGAP25 ARHGAP35 CLPX MAP2K1 FGD6 CCNK DEPDC1B SLX4 CCNC

2.94e-0514187116GO:0030234
GeneOntologyMolecularFunctionprotein domain specific binding

NOLC1 TBC1D10A PIK3R1 CD2AP CD40 ADGRB1 RAPGEF1 ARHGAP17 TRPV4 OSTF1 DMD TP53BP2

5.48e-058757112GO:0019904
GeneOntologyMolecularFunctionRNA polymerase II CTD heptapeptide repeat modifying activity

CDK12 BRD4 CCNK

7.25e-0523713GO:0140994
GeneOntologyMolecularFunctionenzyme activator activity

TBC1D10A PIK3R1 ARHGAP17 ARHGAP25 ARHGAP35 CLPX MAP2K1 CCNK DEPDC1B SLX4

1.04e-046567110GO:0008047
GeneOntologyMolecularFunctionSH3 domain binding

CD2AP RAPGEF1 ARHGAP17 OSTF1 TP53BP2

1.56e-04143715GO:0017124
GeneOntologyMolecularFunctionchromatin binding

H1-8 SMARCA5 ARID1B BRD4 SMARCA1 KMT2A ADNP AHDC1 CIC PHF21A

2.72e-047397110GO:0003682
GeneOntologyMolecularFunctionactin binding

SYNPO2 PHACTR2 MYL4 CD2AP TRPV4 SORBS1 DMD UTRN

2.93e-04479718GO:0003779
GeneOntologyMolecularFunctionnucleosome binding

H1-8 SMARCA5 ARID1B SMARCA1

4.12e-0498714GO:0031491
GeneOntologyMolecularFunctionnucleoside-triphosphatase regulator activity

TBC1D10A KALRN RAPGEF1 ARHGAP17 ARHGAP25 ARHGAP35 FGD6 DEPDC1B

4.28e-04507718GO:0060589
GeneOntologyMolecularFunctionGTPase regulator activity

TBC1D10A KALRN RAPGEF1 ARHGAP17 ARHGAP25 ARHGAP35 FGD6 DEPDC1B

4.28e-04507718GO:0030695
GeneOntologyMolecularFunctionvinculin binding

DMD UTRN

9.48e-0413712GO:0017166
GeneOntologyMolecularFunctionphosphatidylinositol 3-kinase regulatory subunit binding

PIK3R1 CD2AP

1.10e-0314712GO:0036312
GeneOntologyBiologicalProcessactin cytoskeleton organization

SYNPO2 PHACTR2 PIK3R1 PCLO CD2AP ADGRB1 ARHGAP17 TRPV4 ARHGAP25 SORBS1 THSD7B ARHGAP35 FGD6

2.61e-068037013GO:0030036
GeneOntologyBiologicalProcessactin filament-based process

SYNPO2 PHACTR2 PIK3R1 PCLO CD2AP ADGRB1 ARHGAP17 TRPV4 ARHGAP25 SORBS1 THSD7B ARHGAP35 FGD6

1.04e-059127013GO:0030029
GeneOntologyBiologicalProcesssynaptic signaling

PLK2 ARID1B PCLO CD2AP GLRB ADGRB1 KMT2A SORBS1 DMD ADNP UTRN RPH3A GABRA2

2.13e-059767013GO:0099536
GeneOntologyBiologicalProcesspositive regulation of transcription elongation by RNA polymerase II

CDK12 BRD4 MAP2K1 CCNK

3.38e-0554704GO:0032968
GeneOntologyBiologicalProcesspositive regulation of DNA-templated transcription, elongation

CDK12 BRD4 MAP2K1 CCNK

5.85e-0562704GO:0032786
GeneOntologyBiologicalProcessnegative regulation of small GTPase mediated signal transduction

CD2AP RAPGEF1 ARHGAP25 ARHGAP35

7.93e-0567704GO:0051058
GeneOntologyBiologicalProcesscell junction organization

KALRN PIK3R1 PCLO CD2AP GLRB ADGRB1 RAPGEF1 TRPV4 SORBS1 ADNP RPH3A GABRA2

9.72e-059747012GO:0034330
GeneOntologyBiologicalProcesssynapse organization

KALRN PIK3R1 PCLO CD2AP GLRB ADGRB1 SORBS1 ADNP RPH3A GABRA2

1.00e-046857010GO:0050808
GeneOntologyBiologicalProcessregulation of small GTPase mediated signal transduction

KALRN CD2AP RAPGEF1 ARHGAP17 ARHGAP25 ARHGAP35 MAP2K1

1.35e-04333707GO:0051056
GeneOntologyBiologicalProcessregulation of GTPase activity

TBC1D10A KALRN CD40 RAPGEF1 ARHGAP17 ARHGAP25 FGD6

1.40e-04335707GO:0043087
GeneOntologyBiologicalProcesspositive regulation of GTPase activity

TBC1D10A KALRN CD40 RAPGEF1 ARHGAP17 ARHGAP25

1.80e-04244706GO:0043547
GeneOntologyBiologicalProcessanterograde trans-synaptic signaling

PLK2 ARID1B PCLO CD2AP GLRB ADGRB1 KMT2A DMD ADNP RPH3A GABRA2

2.81e-049317011GO:0098916
GeneOntologyBiologicalProcesschemical synaptic transmission

PLK2 ARID1B PCLO CD2AP GLRB ADGRB1 KMT2A DMD ADNP RPH3A GABRA2

2.81e-049317011GO:0007268
GeneOntologyBiologicalProcessregulation of transcription elongation by RNA polymerase II

CDK12 BRD4 MAP2K1 CCNK

2.83e-0493704GO:0034243
GeneOntologyBiologicalProcesstrans-synaptic signaling

PLK2 ARID1B PCLO CD2AP GLRB ADGRB1 KMT2A DMD ADNP RPH3A GABRA2

3.03e-049397011GO:0099537
GeneOntologyBiologicalProcessactin filament organization

SYNPO2 PIK3R1 CD2AP ARHGAP17 TRPV4 ARHGAP25 SORBS1 ARHGAP35

3.21e-04509708GO:0007015
GeneOntologyCellularComponentnuclear cyclin-dependent protein kinase holoenzyme complex

CDK12 BRD4 CCNK CCNC

3.40e-0718704GO:0019908
GeneOntologyCellularComponentcyclin/CDK positive transcription elongation factor complex

CDK12 BRD4 CCNK

2.98e-069703GO:0008024
GeneOntologyCellularComponentcyclin K-CDK12 complex

CDK12 CCNK

1.11e-052702GO:0002944
GeneOntologyCellularComponentcyclin-dependent protein kinase holoenzyme complex

CDK12 BRD4 CCNK CCNC

5.21e-0561704GO:0000307
GeneOntologyCellularComponentcarboxy-terminal domain protein kinase complex

CDK12 BRD4 CCNK

6.92e-0524703GO:0032806
GeneOntologyCellularComponenttransferase complex, transferring phosphorus-containing groups

TAF3 CDK12 PIK3R1 BRD4 PRIM2 CCNK CCNC

1.29e-04335707GO:0061695
GeneOntologyCellularComponentnuclear protein-containing complex

NOLC1 SMARCA5 ARID1B TAF3 CDK12 BRD4 PRIM2 SMARCA1 KMT2A ADNP CCNK SLX4 PHF21A CCNC

1.61e-0413777014GO:0140513
GeneOntologyCellularComponentNURF complex

SMARCA5 SMARCA1

2.30e-047702GO:0016589
GeneOntologyCellularComponentanchoring junction

SYNPO2 SCARF2 PIK3R1 CD2AP ADGRB1 ARHGAP17 TRPV4 SORBS1 DMD MAP2K1 FYB1

3.76e-049767011GO:0070161
GeneOntologyCellularComponentneuromuscular junction

PCLO CD2AP UTRN RPH3A

5.45e-04112704GO:0031594
GeneOntologyCellularComponentactin cytoskeleton

SYNPO2 MYL4 KALRN CD2AP TRPV4 SORBS1 ARHGAP35 FYB1

6.66e-04576708GO:0015629
GeneOntologyCellularComponentcell-substrate junction

SYNPO2 SCARF2 ADGRB1 TRPV4 SORBS1 DMD MAP2K1

6.95e-04443707GO:0030055
GeneOntologyCellularComponentsomatodendritic compartment

PLK2 KALRN PCLO CD2AP GLRB CD40 ADGRB1 DMD ADNP MAP2K1 RPH3A GABRA2

7.17e-0412287012GO:0036477
GeneOntologyCellularComponenttranscription elongation factor complex

CDK12 BRD4 CCNK

8.78e-0456703GO:0008023
GeneOntologyCellularComponentISWI-type complex

SMARCA5 SMARCA1

9.80e-0414702GO:0031010
GeneOntologyCellularComponentperinuclear region of cytoplasm

GLB1 KALRN PIK3R1 PCLO CD2AP ADGRB1 RAPGEF1 DMD MAP2K1 TP53BP2

1.05e-039347010GO:0048471
GeneOntologyCellularComponentpostsynaptic specialization

KALRN PCLO GLRB ADGRB1 DMD MAP2K1 GABRA2

1.45e-03503707GO:0099572
GeneOntologyCellularComponentserine/threonine protein kinase complex

CDK12 BRD4 CCNK CCNC

1.91e-03157704GO:1902554
GeneOntologyCellularComponentpostsynapse

KALRN PCLO GLRB ADGRB1 DMD MAP2K1 UTRN RPH3A AP3D1 GABRA2

2.00e-0310187010GO:0098794
GeneOntologyCellularComponentdystrophin-associated glycoprotein complex

DMD UTRN

2.02e-0320702GO:0016010
GeneOntologyCellularComponentdendrite

PLK2 PCLO CD2AP GLRB ADGRB1 ADNP MAP2K1 RPH3A GABRA2

2.19e-03858709GO:0030425
GeneOntologyCellularComponentdendritic tree

PLK2 PCLO CD2AP GLRB ADGRB1 ADNP MAP2K1 RPH3A GABRA2

2.22e-03860709GO:0097447
GeneOntologyCellularComponentfilopodium membrane

DMD UTRN

2.23e-0321702GO:0031527
GeneOntologyCellularComponentGABA-ergic synapse

PCLO GLRB DMD GABRA2

2.24e-03164704GO:0098982
GeneOntologyCellularComponentpostsynaptic membrane

GLRB ADGRB1 DMD UTRN RPH3A GABRA2

2.35e-03405706GO:0045211
GeneOntologyCellularComponentprotein kinase complex

CDK12 BRD4 CCNK CCNC

2.55e-03170704GO:1902911
GeneOntologyCellularComponentaxon

PCLO CD2AP CD40 TRPV4 DMD ADNP MAP2K1 AP3D1 GABRA2

2.82e-03891709GO:0030424
GeneOntologyCellularComponentglycoprotein complex

DMD UTRN

3.15e-0325702GO:0090665
GeneOntologyCellularComponentfocal adhesion

SYNPO2 SCARF2 ADGRB1 TRPV4 SORBS1 MAP2K1

3.20e-03431706GO:0005925
GeneOntologyCellularComponentSWI/SNF superfamily-type complex

SMARCA5 ARID1B SMARCA1

4.11e-0396703GO:0070603
GeneOntologyCellularComponentinhibitory synapse

PCLO GABRA2

4.83e-0331702GO:0060077
GeneOntologyCellularComponentphagocytic cup

ADGRB1 ARHGAP25

4.83e-0331702GO:0001891
HumanPhenoAbnormality of refraction

ZNF469 ARID1B PIK3R1 BRD4 GLRB TRPV4 ADNP MAP2K1 CHAMP1 AHDC1 VARS1 AP3D1 SLX4 RAI1

2.41e-057093114HP:0000539
HumanPhenoAbnormal location of ears

ARID1B GLB1 SCARF2 PIK3R1 BRD4 PCLO KMT2A TRPV4 ADNP MAP2K1 CHAMP1 CCNK AHDC1 VARS1 AP3D1 RAI1

3.17e-059453116HP:0000357
HumanPhenoPes planus

ZNF469 SCARF2 KMT2A TRPV4 DMD ADNP CCNK CIC SLX4 RAI1

3.58e-053653110HP:0001763
HumanPhenoRadial deviation of finger

ARID1B PIK3R1 BRD4 KMT2A TRPV4 ADNP MAP2K1 CCNK SLX4 PHF21A RAI1

3.59e-054483111HP:0009466
HumanPhenoRadial deviation of the hand or of fingers of the hand

ARID1B PIK3R1 BRD4 KMT2A TRPV4 ADNP MAP2K1 CCNK SLX4 PHF21A RAI1

4.24e-054563111HP:0009485
HumanPhenoLong palpebral fissure

PCLO KMT2A ADNP MAP2K1 CCNK

5.85e-0571315HP:0000637
HumanPhenoAplasia/Hypoplasia involving the nose

ARID1B SCARF2 PIK3R1 BRD4 KMT2A ADNP MAP2K1 VARS1 PHF21A RAI1

8.03e-054013110HP:0009924
HumanPhenoDeviation of finger

ARID1B PIK3R1 BRD4 KMT2A TRPV4 ADNP MAP2K1 CCNK SLX4 PHF21A RAI1

1.90e-045373111HP:0004097
HumanPhenoAbnormal cornea morphology

ZNF469 ARID1B GLB1 SCARF2 PIK3R1 BRD4 GLRB TRPV4 ADNP VARS1 AP3D1 SLX4 RAI1

2.00e-047443113HP:0000481
HumanPhenoMyopia

ZNF469 ARID1B PIK3R1 BRD4 GLRB MAP2K1 AHDC1 VARS1 AP3D1 RAI1

2.00e-044473110HP:0000545
HumanPhenoRestricted or repetitive behaviors or interests

ARID1B BRD4 KMT2A ADNP CHAMP1 CCNK VARS1 CIC RAI1

2.35e-04368319HP:0031432
HumanPhenoLow-set ears

ARID1B GLB1 PIK3R1 BRD4 PCLO KMT2A ADNP MAP2K1 CHAMP1 CCNK AHDC1 VARS1 AP3D1

2.52e-047613113HP:0000369
HumanPhenoAstigmatism

ARID1B PIK3R1 GLRB ADNP VARS1 AP3D1 SLX4

2.53e-04217317HP:0000483
HumanPhenoAbnormality of corneal size

ZNF469 ARID1B PIK3R1 BRD4 GLRB ADNP VARS1 AP3D1 SLX4 RAI1

2.59e-044613110HP:0001120
HumanPhenoJoint hypermobility

ZNF469 ARID1B GLB1 SCARF2 PIK3R1 KMT2A TRPV4 ADNP CHAMP1 AHDC1 RAI1

2.64e-045573111HP:0001382
HumanPhenoPerseverative thought

ARID1B BRD4 KMT2A ADNP CHAMP1 CCNK VARS1 CIC RAI1

2.82e-04377319HP:0030223
HumanPhenoAbnormal calvaria morphology

ARID1B GLB1 SCARF2 PIK3R1 BRD4 PCLO KMT2A TRPV4 ADNP MAP2K1 CHAMP1 AHDC1 VARS1 SLX4 PHF21A RAI1 GABRA2

2.88e-0412543117HP:0002683
HumanPhenoDeviation of the hand or of fingers of the hand

ARID1B PIK3R1 BRD4 KMT2A TRPV4 ADNP MAP2K1 CCNK SLX4 PHF21A RAI1

2.95e-045643111HP:0009484
HumanPhenoAbnormality of calvarial morphology

ARID1B GLB1 SCARF2 PIK3R1 BRD4 PCLO KMT2A TRPV4 ADNP MAP2K1 CHAMP1 AHDC1 SLX4 PHF21A RAI1 GABRA2

3.16e-0411343116HP:0002648
HumanPhenoBroad nasal tip

ARID1B GLB1 KMT2A ADNP CCNK PHF21A

3.24e-04159316HP:0000455
HumanPhenoDisordered formal thought process

ARID1B BRD4 KMT2A ADNP CHAMP1 CCNK VARS1 CIC RAI1

3.37e-04386319HP:0025769
HumanPhenoClinodactyly

ARID1B PIK3R1 BRD4 KMT2A TRPV4 ADNP MAP2K1 CCNK SLX4 PHF21A RAI1

3.45e-045743111HP:0030084
HumanPhenoAbnormality of the radioulnar joints

SCARF2 TRPV4

3.54e-045312HP:0003059
HumanPhenoLong fingers

ZNF469 SCARF2 BRD4 KMT2A ADNP CCNK CIC PHF21A

3.61e-04306318HP:0100807
HumanPhenoAbnormal nasal bridge morphology

ARID1B GLB1 SCARF2 PIK3R1 BRD4 PCLO KMT2A TRPV4 ADNP MAP2K1 CCNK AHDC1 VARS1 PHF21A RAI1

3.91e-0410293115HP:0000422
HumanPhenoGenu valgum

PHLDB1 GLB1 SCARF2 TRPV4 ADNP MAP2K1

3.96e-04165316HP:0002857
HumanPhenoAbnormal pinna morphology

ARID1B GLB1 SCARF2 PIK3R1 BRD4 PCLO KMT2A TRPV4 ADNP MAP2K1 CHAMP1 CCNK AHDC1 VARS1 AP3D1 SLX4 RAI1

4.53e-0412993117HP:0000377
HumanPhenoAbnormal forearm morphology

ARID1B SCARF2 BRD4 TRPV4 MAP2K1 SLX4 RAI1

4.58e-04239317HP:0002973
HumanPhenoAbnormal thought pattern

ARID1B BRD4 KMT2A ADNP CHAMP1 CCNK VARS1 CIC RAI1

4.73e-04404319HP:5200269
HumanPhenoDepressed nasal bridge

ARID1B GLB1 SCARF2 BRD4 PCLO TRPV4 ADNP MAP2K1 AHDC1 VARS1 RAI1

6.04e-046123111HP:0005280
HumanPhenoFlattened nasal bridge

ARID1B GLB1 SCARF2 BRD4 PCLO TRPV4 ADNP MAP2K1 AHDC1 VARS1 RAI1

6.04e-046123111HP:0000425
HumanPhenoClinodactyly of the 5th finger

ARID1B BRD4 KMT2A TRPV4 ADNP CCNK SLX4 PHF21A RAI1

6.30e-04420319HP:0004209
HumanPhenoClinodactyly of hands

ARID1B BRD4 KMT2A TRPV4 ADNP CCNK SLX4 PHF21A RAI1

6.41e-04421319HP:0001157
HumanPhenoDeviation of the 5th finger

ARID1B BRD4 KMT2A TRPV4 ADNP CCNK SLX4 PHF21A RAI1

6.41e-04421319HP:0009179
HumanPhenoAbnormality of the outer ear

ARID1B GLB1 SCARF2 PIK3R1 BRD4 PCLO KMT2A TRPV4 ADNP MAP2K1 CHAMP1 CCNK AHDC1 VARS1 AP3D1 SLX4 RAI1

6.52e-0413373117HP:0000356
HumanPhenoAbnormality of the philtrum

ARID1B GLB1 BRD4 PCLO KMT2A ADNP MAP2K1 CHAMP1 CCNK AP3D1 PHF21A RAI1

6.68e-047263112HP:0000288
HumanPhenoAbnormality of the curvature of the cornea

ZNF469 ARID1B PIK3R1 GLRB ADNP VARS1 AP3D1 SLX4

6.79e-04336318HP:0100691
HumanPhenoLong philtrum

ARID1B GLB1 BRD4 PCLO KMT2A ADNP MAP2K1 CCNK RAI1

7.36e-04429319HP:0000343
HumanPhenoFlattened femoral head

GLB1 TRPV4

7.39e-047312HP:0008812
HumanPhenoAbnormal morphology of the nasal alae

ARID1B GLB1 SCARF2 PIK3R1 BRD4 KMT2A ADNP MAP2K1 CCNK PHF21A RAI1

8.76e-046393111HP:0000429
DomainSH3

PRAM1 KALRN PIK3R1 CD2AP OSTF1 SORBS1 FYB1 TP53BP2

1.60e-06216718SM00326
DomainSH3

PRAM1 KALRN PIK3R1 CD2AP OSTF1 SORBS1 FYB1 TP53BP2

1.60e-06216718PS50002
DomainSH3_domain

PRAM1 KALRN PIK3R1 CD2AP OSTF1 SORBS1 FYB1 TP53BP2

1.84e-06220718IPR001452
DomainRhoGAP

PIK3R1 ARHGAP17 ARHGAP25 ARHGAP35 DEPDC1B

4.08e-0663715PF00620
DomainRHOGAP

PIK3R1 ARHGAP17 ARHGAP25 ARHGAP35 DEPDC1B

4.41e-0664715PS50238
DomainRhoGAP_dom

PIK3R1 ARHGAP17 ARHGAP25 ARHGAP35 DEPDC1B

4.41e-0664715IPR000198
Domain-

PIK3R1 ARHGAP17 ARHGAP25 ARHGAP35 DEPDC1B

4.41e-06647151.10.555.10
DomainSLIDE

SMARCA5 SMARCA1

1.42e-052712IPR015195
DomainISWI_HAND-dom

SMARCA5 SMARCA1

1.42e-052712IPR015194
DomainSLIDE

SMARCA5 SMARCA1

1.42e-052712PF09111
DomainHAND

SMARCA5 SMARCA1

1.42e-052712PF09110
DomainDystrophin

DMD UTRN

1.42e-052712IPR016344
DomainISWI

SMARCA5 SMARCA1

1.42e-052712IPR029915
DomainZnf_FYVE_PHD

TAF3 PCLO KMT2A FGD6 RPH3A PHF21A

2.02e-05147716IPR011011
DomainRho_GTPase_activation_prot

PIK3R1 ARHGAP17 ARHGAP25 ARHGAP35 DEPDC1B

2.11e-0588715IPR008936
DomainhSH3

PRAM1 FYB1

4.26e-053712IPR029294
DomainhSH3

PRAM1 FYB1

4.26e-053712PF14603
DomainDBINO

SMARCA5 SMARCA1

4.26e-053712PF13892
DomainDBINO

SMARCA5 SMARCA1

4.26e-053712IPR020838
DomainSpectrin

KALRN DMD UTRN

8.83e-0523713PF00435
DomainRhoGAP

PIK3R1 ARHGAP17 ARHGAP25 ARHGAP35

9.06e-0562714SM00324
DomainAT_hook

KMT2A AHDC1 PHF21A

1.44e-0427713SM00384
DomainAT_hook_DNA-bd_motif

KMT2A AHDC1 PHF21A

1.44e-0427713IPR017956
DomainSpectrin_repeat

KALRN DMD UTRN

1.79e-0429713IPR002017
DomainEF-hand_dom_typ1

DMD UTRN

2.12e-046712IPR015153
DomainEF-hand_dom_typ2

DMD UTRN

2.12e-046712IPR015154
DomainEF-hand_2

DMD UTRN

2.12e-046712PF09068
DomainEF-hand_3

DMD UTRN

2.12e-046712PF09069
DomainSpectrin/alpha-actinin

KALRN DMD UTRN

2.41e-0432713IPR018159
DomainSPEC

KALRN DMD UTRN

2.41e-0432713SM00150
DomainSH3_2

PIK3R1 CD2AP SORBS1 FYB1

3.22e-0486714IPR011511
DomainSH3_2

PIK3R1 CD2AP SORBS1 FYB1

3.22e-0486714PF07653
DomainPHD

TAF3 KMT2A PHF21A RAI1

3.67e-0489714SM00249
DomainZnf_PHD

TAF3 KMT2A PHF21A RAI1

3.99e-0491714IPR001965
DomainSH3_1

PIK3R1 CD2AP OSTF1 SORBS1 TP53BP2

4.01e-04164715PF00018
DomainZF_PHD_2

TAF3 KMT2A PHF21A RAI1

4.70e-0495714PS50016
DomainZF_PHD_1

TAF3 KMT2A PHF21A RAI1

4.89e-0496714PS01359
DomainAT_hook

KMT2A PHF21A

1.65e-0316712PF02178
DomainCH

MICALL1 DMD UTRN

1.94e-0365713SM00033
DomainZZ

DMD UTRN

2.10e-0318712PF00569
DomainZF_ZZ_2

DMD UTRN

2.10e-0318712PS50135
DomainZF_ZZ_1

DMD UTRN

2.10e-0318712PS01357
DomainZnf_ZZ

DMD UTRN

2.34e-0319712IPR000433
DomainZnF_ZZ

DMD UTRN

2.34e-0319712SM00291
DomainCH

MICALL1 DMD UTRN

2.40e-0370713PF00307
Domain-

MICALL1 DMD UTRN

2.50e-03717131.10.418.10
DomainSynaptotagmin

PCLO RPH3A

2.59e-0320712IPR001565
DomainCH

MICALL1 DMD UTRN

2.71e-0373713PS50021
DomainPHD

TAF3 KMT2A PHF21A

2.92e-0375713PF00628
DomainCH-domain

MICALL1 DMD UTRN

2.92e-0375713IPR001715
DomainEPHD

KMT2A RAI1

3.13e-0322712PS51805
DomainZnf_PHD-finger

TAF3 KMT2A PHF21A

3.39e-0379713IPR019787
DomainActinin_actin-bd_CS

DMD UTRN

3.42e-0323712IPR001589
DomainACTININ_2

DMD UTRN

3.42e-0323712PS00020
DomainACTININ_1

DMD UTRN

3.42e-0323712PS00019
DomainSANT_dom

SMARCA5 SMARCA1

4.37e-0326712IPR017884
DomainSANT

SMARCA5 SMARCA1

5.05e-0328712PS51293
DomainCYCLINS

CCNK CCNC

5.05e-0328712PS00292
DomainSNF2_N

SMARCA5 SMARCA1

6.57e-0332712IPR000330
DomainSNF2_N

SMARCA5 SMARCA1

6.57e-0332712PF00176
DomainCyclin_N

CCNK CCNC

6.97e-0333712IPR006671
DomainCyclin_N

CCNK CCNC

6.97e-0333712PF00134
Domain-

TAF3 PCLO KMT2A FGD6 RPH3A PHF21A

7.17e-034497163.30.40.10
DomainZnf_FYVE-rel

FGD6 RPH3A

7.39e-0334712IPR017455
PathwayREACTOME_RAC3_GTPASE_CYCLE

PIK3R1 RAPGEF1 ARHGAP17 ARHGAP35 DEPDC1B

3.01e-0593555MM15609
PathwayREACTOME_RHOJ_GTPASE_CYCLE

PIK3R1 ARHGAP35 DEPDC1B

3.04e-0516553MM15605
PathwayREACTOME_RAC3_GTPASE_CYCLE

PIK3R1 RAPGEF1 ARHGAP17 ARHGAP35 DEPDC1B

3.17e-0594555M41818
PathwayREACTOME_RHOD_GTPASE_CYCLE

PIK3R1 ARHGAP17 ARHGAP35 DEPDC1B

5.27e-0553554M41811
PathwayREACTOME_RAC1_GTPASE_CYCLE

KALRN PIK3R1 ARHGAP17 ARHGAP25 ARHGAP35 DEPDC1B

5.88e-05175556MM15599
PathwayREACTOME_RAC1_GTPASE_CYCLE

KALRN PIK3R1 ARHGAP17 ARHGAP25 ARHGAP35 DEPDC1B

7.77e-05184556M41809
PathwayPID_FAK_PATHWAY

PIK3R1 RAPGEF1 ARHGAP35 MAP2K1

8.05e-0559554M281
PathwayREACTOME_RHOD_GTPASE_CYCLE

PIK3R1 ARHGAP17 ARHGAP35 DEPDC1B

1.11e-0464554MM15601
PathwayREACTOME_RHOG_GTPASE_CYCLE

KALRN PIK3R1 ARHGAP35 DEPDC1B

1.66e-0471554MM15604
PathwayREACTOME_RHOG_GTPASE_CYCLE

KALRN PIK3R1 ARHGAP35 DEPDC1B

1.95e-0474554M41814
PathwayBIOCARTA_MET_PATHWAY

PIK3R1 RAPGEF1 MAP2K1

2.82e-0433553M19358
PathwayBIOCARTA_MET_PATHWAY

PIK3R1 RAPGEF1 MAP2K1

2.82e-0433553MM1494
PathwayREACTOME_RAC2_GTPASE_CYCLE

PIK3R1 ARHGAP17 ARHGAP35 DEPDC1B

3.63e-0487554MM15600
PathwayREACTOME_RAC2_GTPASE_CYCLE

PIK3R1 ARHGAP17 ARHGAP35 DEPDC1B

3.79e-0488554M41810
PathwayREACTOME_CDC42_GTPASE_CYCLE

PIK3R1 ARHGAP17 ARHGAP35 DEPDC1B

4.87e-0494554MM15598
PathwayPID_IFNG_PATHWAY

PIK3R1 RAPGEF1 MAP2K1

5.01e-0440553M161
PathwayPID_EPHB_FWD_PATHWAY

KALRN PIK3R1 MAP2K1

5.01e-0440553M62
PathwayWP_B_CELL_RECEPTOR_SIGNALING

PIK3R1 RAPGEF1 MAP2K1 MEF2D

5.49e-0497554M39323
PathwayREACTOME_RND3_GTPASE_CYCLE

PIK3R1 ARHGAP35 DEPDC1B

5.79e-0442553M41826
PathwayREACTOME_RND1_GTPASE_CYCLE

PIK3R1 ARHGAP35 DEPDC1B

5.79e-0442553M41828
PathwayREACTOME_RND3_GTPASE_CYCLE

PIK3R1 ARHGAP35 DEPDC1B

5.79e-0442553MM15677
PathwayREACTOME_RND2_GTPASE_CYCLE

PIK3R1 ARHGAP35 DEPDC1B

6.21e-0443553M41827
PathwayREACTOME_RND1_GTPASE_CYCLE

PIK3R1 ARHGAP35 DEPDC1B

6.21e-0443553MM15679
PathwayPID_INSULIN_PATHWAY

PIK3R1 RAPGEF1 SORBS1

6.65e-0444553M16
PathwayREACTOME_RND2_GTPASE_CYCLE

PIK3R1 ARHGAP35 DEPDC1B

6.65e-0444553MM15678
PathwayWP_IL3_SIGNALING

PIK3R1 RAPGEF1 MAP2K1

9.12e-0449553M39722
PathwaySIG_INSULIN_RECEPTOR_PATHWAY_IN_CARDIAC_MYOCYTES

PIK3R1 BRD4 SORBS1

1.03e-0351553M7955
Pubmed

The Nse5/6-like SIMC1-SLF2 complex localizes SMC5/6 to viral replication centers.

NOLC1 PRAM1 SMARCA5 ARID1B TAF3 CDK12 RBM19 BRD4 CD2AP ZNF280C KMT2A ZFR ADNP CHAMP1 DDX24 CCNK CIC MEF2D SLX4 RAI1 TASOR2 NDUFV3

1.20e-17954712236373674
Pubmed

NuRD subunit CHD4 regulates super-enhancer accessibility in rhabdomyosarcoma and represents a general tumor dependency.

NOLC1 SMARCA5 BRD4 SMARCA1 KMT2A ADNP CHAMP1 DDX24 RAI1

7.84e-1310371932744500
Pubmed

A central chaperone-like role for 14-3-3 proteins in human cells.

MICALL1 NOLC1 PLK2 PHLDB1 PHACTR2 BRD4 CD2AP KMT2A ARHGAP17 SORBS1 MAP2K1 FGD6 UTRN DEPDC1B CIC MEF2D TP53BP2

1.25e-12861711736931259
Pubmed

Nuclear actin interactome analysis links actin to KAT14 histone acetyl transferase and mRNA splicing.

NOLC1 SMARCA5 PHACTR2 CDK12 BRD4 PRIM2 ZFR SORBS1 ARHGAP35 ADNP UTRN CCNK CIC

3.03e-11506711330890647
Pubmed

N-Terminal Acetyltransferase Naa40p Whereabouts Put into N-Terminal Proteoform Perspective.

NOLC1 SMARCA5 CDK12 ZNF280C KMT2A ZFR ARHGAP35 ADNP CHAMP1 UTRN CCNK DEPDC1B AP3D1 CIC PHF21A TP53BP2

5.19e-11934711633916271
Pubmed

SRCAP complex promotes lung cancer progression by reprograming the oncogenic transcription of Hippo-YAP/TAZ signaling pathway.

SMARCA5 ARID1B TAF3 CDK12 BRD4 CD2AP KMT2A ZFR ARHGAP35 ADNP CHAMP1 CCNK TP53BP2

8.27e-11549711338280479
Pubmed

Proximity-dependent Mapping of the Androgen Receptor Identifies Kruppel-like Factor 4 as a Functional Partner.

ARID1B BRD4 KMT2A CHAMP1 CCNK AHDC1 CIC MEF2D PHF21A RAI1

1.91e-10268711033640491
Pubmed

MECP2 directly interacts with RNA polymerase II to modulate transcription in human neurons.

NOLC1 SMARCA5 ARID1B TAF3 KALRN CDK12 BRD4 ARHGAP35 ADNP CHAMP1 DDX24 CCNK AHDC1 VARS1 AP3D1

4.03e-091082711538697112
Pubmed

Systems analysis of RhoGEF and RhoGAP regulatory proteins reveals spatially organized RAC1 signalling from integrin adhesions.

SMARCA5 PIK3R1 CD2AP KMT2A ARHGAP17 ZFR ARHGAP25 DMD ARHGAP35 CLPX FGD6 UTRN DEPDC1B NDUFV3

4.19e-09916711432203420
Pubmed

Large-scale characterization of HeLa cell nuclear phosphoproteins.

MICALL1 NOLC1 SMARCA5 TAF3 CDK12 BRD4 KMT2A ARHGAP35 CHAMP1 DDX24 CCNK CIC MEF2D

5.27e-09774711315302935
Pubmed

WDR76 Co-Localizes with Heterochromatin Related Proteins and Rapidly Responds to DNA Damage.

SMARCA5 BRD4 CD2AP KMT2A ZFR CHAMP1 DDX24 UTRN VARS1 RAI1

7.76e-09394711027248496
Pubmed

The ubiquitin ligase Uhrf2 is a master regulator of cholesterol biosynthesis and is essential for liver regeneration.

NOLC1 SMARCA5 KMT2A ADNP CHAMP1 TASOR2

2.41e-088671637253089
Pubmed

Systematic identification of SH3 domain-mediated human protein-protein interactions by peptide array target screening.

PHACTR2 SCARF2 PIK3R1 BRD4 CD2AP RAPGEF1 ADNP FYB1 TP53BP2

2.42e-0832971917474147
Pubmed

Interaction network of human early embryonic transcription factors.

SMARCA5 ARID1B TAF3 SMARCA1 KMT2A AHDC1 SLX4 PHF21A RAI1

4.21e-0835171938297188
Pubmed

The in vivo Interaction Landscape of Histones H3.1 and H3.3.

SMARCA5 TAF3 BRD4 ZNF280C SMARCA1 KMT2A ADNP CHAMP1 DDX24 CIC RAI1

4.22e-08608711136089195
Pubmed

A novel role for the peptidyl-prolyl cis-trans isomerase Cyclophilin A in DNA-repair following replication fork stalling via the MRE11-RAD50-NBS1 complex.

ARID1B CDK12 ZNF280C ARHGAP35 MAP2K1 CHAMP1 CCNK CIC MEF2D TP53BP2

4.25e-08472711038943005
Pubmed

PRISMA and BioID disclose a motifs-based interactome of the intrinsically disordered transcription factor C/EBPα.

NOLC1 PRAM1 ARID1B BRD4 KMT2A ZFR ADNP CCNK AHDC1 VARS1 CIC MEF2D PHF21A RAI1

4.29e-081103711434189442
Pubmed

SETD1A Methyltransferase Is Physically and Functionally Linked to the DNA Damage Repair Protein RAD18.

NOLC1 SMARCA5 CDK12 SMARCA1 KMT2A ZFR CHAMP1 CCNK

4.73e-0825171831076518
Pubmed

Cooperative polarization of MCAM/CD146 and ERM family proteins in melanoma.

MICALL1 PHLDB1 TBC1D10A SCARF2 ADGRB1 TRPV4 DMD UTRN DEPDC1B

7.74e-0837771938117590
Pubmed

Mapping the Ku Interactome Using Proximity-Dependent Biotin Identification in Human Cells.

SMARCA5 CDK12 BRD4 ZNF280C ZFR ADNP CHAMP1 CCNK

1.19e-0728371830585729
Pubmed

In-Depth In Vivo Crosslinking in Minutes by a Compact, Membrane-Permeable, and Alkynyl-Enrichable Crosslinker.

NOLC1 SMARCA5 PHACTR2 PCLO SMARCA1 KMT2A ZFR CEND1 DMD CLPX SPAG17 VARS1 AP3D1 RAI1 TASOR2

1.76e-071442711535575683
Pubmed

Quantitative interaction proteomics and genome-wide profiling of epigenetic histone marks and their readers.

SMARCA5 TAF3 SMARCA1 ADNP CHAMP1 AHDC1

2.15e-0712471620850016
Pubmed

A dual-activity topoisomerase complex regulates mRNA translation and turnover.

MICALL1 PHLDB1 KALRN CDK12 RBM19 BRD4 RAPGEF1 ARHGAP17 ARHGAP35 AHDC1 AP3D1 CIC RAI1

3.30e-071105711335748872
Pubmed

Systematic bromodomain protein screens identify homologous recombination and R-loop suppression pathways involved in genome integrity.

NOLC1 ZNF469 SMARCA5 ARID1B TAF3 PIK3R1 BRD4 SMARCA1 CLPX CHAMP1 DDX24 PHF21A RAI1

3.69e-071116711331753913
Pubmed

Defining the NSD2 interactome: PARP1 PARylation reduces NSD2 histone methyltransferase activity and impedes chromatin binding.

SMARCA5 BRD4 ZNF280C ADNP CHAMP1

3.87e-077271531248990
Pubmed

MYC Protein Interactome Profiling Reveals Functionally Distinct Regions that Cooperate to Drive Tumorigenesis.

ARID1B BRD4 KMT2A ADNP CHAMP1 DDX24 CCNK PHF21A

4.68e-0733971830415952
Pubmed

Proteomic profiling of VCP substrates links VCP to K6-linked ubiquitylation and c-Myc function.

NOLC1 SMARCA5 PHLDB1 RBM19 PRIM2 SMARCA1 ZFR CLPX ADNP DDX24 UTRN VARS1 AP3D1 TP53BP2

5.14e-071353711429467282
Pubmed

A human MAP kinase interactome.

SYNPO2 PIK3R1 RAPGEF1 ARHGAP17 SORBS1 DMD MAP2K1 CIC MEF2D

6.52e-0748671920936779
Pubmed

Synthetic Lethal and Resistance Interactions with BET Bromodomain Inhibitors in Triple-Negative Breast Cancer.

NOLC1 SMARCA5 TAF3 CDK12 BRD4 PRIM2 KMT2A ZFR ADNP CHAMP1 CCNK CCNC

9.30e-071014711232416067
Pubmed

Human transcription factor protein interaction networks.

NOLC1 SMARCA5 ARID1B TAF3 SMARCA1 KMT2A ZFR CLPX ADNP DDX24 CIC MEF2D SLX4 PHF21A

9.83e-071429711435140242
Pubmed

Prediction of the coding sequences of mouse homologues of KIAA gene: III. the complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.

MICALL1 NOLC1 ARID1B CDK12 ZNF280C ADNP CHAMP1 PHF21A RAI1

1.31e-0652971914621295
Pubmed

Interactome Rewiring Following Pharmacological Targeting of BET Bromodomains.

NOLC1 SMARCA5 TAF3 BRD4 SMARCA1 KMT2A TMEM214 ADNP CCNC

1.40e-0653371930554943
Pubmed

KAP1 facilitates reinstatement of heterochromatin after DNA replication.

SMARCA5 GLB1 CDK12 PRIM2 SMARCA1 ZFR CLPX CHAMP1 DDX24 AP3D1

1.65e-06704711029955894
Pubmed

H4K20me0 recognition by BRCA1-BARD1 directs homologous recombination to sister chromatids.

NOLC1 SMARCA5 BRD4 KMT2A ZFR TMEM214 ADNP CHAMP1 DDX24 AHDC1 CIC PHF21A RAI1

1.92e-061294711330804502
Pubmed

Proximity-dependent biotin identification (BioID) reveals a dynamic LSD1-CoREST interactome during embryonic stem cell differentiation.

BRD4 CD2AP ADNP CHAMP1 UTRN CIC PHF21A TP53BP2

2.24e-0641871834709266
Pubmed

Proteome-scale mapping of binding sites in the unstructured regions of the human proteome.

ZNF469 SYNPO2 PIK3R1 ZFR ADNP CIC TP53BP2 TASOR2

2.76e-0643071835044719
Pubmed

Identification of SH3 domain interaction partners of human FasL (CD178) by phage display screening.

KALRN PIK3R1 OSTF1 FYB1

3.42e-065071419807924
Pubmed

Proteome-wide identification of HSP70/HSC70 chaperone clients in human cells.

NOLC1 SMARCA5 RBM19 CD2AP CD40 ZFR CLPX ADNP CHAMP1 DDX24 UTRN VARS1 NDUFV3

3.51e-061367711332687490
Pubmed

CHD3 and CHD4 form distinct NuRD complexes with different yet overlapping functionality.

NOLC1 SMARCA5 RBM19 SMARCA1 KMT2A ZFR ADNP DDX24 RAI1

3.92e-0660571928977666
Pubmed

Decreased myocardial nNOS, increased iNOS and abnormal ECGs in mouse models of Duchenne muscular dystrophy.

DMD UTRN

4.11e-06271210525423
Pubmed

Regulation of smooth muscle dystrophin and synaptopodin 2 expression by actin polymerization and vascular injury.

SYNPO2 DMD

4.11e-06271225857312
Pubmed

Distribution of dystrophin- and utrophin-associated protein complexes during activation of human neutrophils.

DMD UTRN

4.11e-06271220434517
Pubmed

Plasma lipidomic analysis shows a disease progression signature in mdx mice.

DMD UTRN

4.11e-06271234155298
Pubmed

In Vivo Genome Editing Restores Dystrophin Expression and Cardiac Function in Dystrophic Mice.

DMD UTRN

4.11e-06271228790199
Pubmed

Dystrophic changes in extraocular muscles after gamma irradiation in mdx:utrophin(+/-) mice.

DMD UTRN

4.11e-06271224466085
Pubmed

The Angiotensin Converting Enzyme Inhibitor Lisinopril Improves Muscle Histopathology but not Contractile Function in a Mouse Model of Duchenne Muscular Dystrophy.

DMD UTRN

4.11e-06271227110493
Pubmed

Rapid depletion of muscle progenitor cells in dystrophic mdx/utrophin-/- mice.

DMD UTRN

4.11e-06271224781208
Pubmed

Isolation and characterization of a genomic clone from the murine utrophin locus.

DMD UTRN

4.11e-0627128268660
Pubmed

Metabolic dysfunction and altered mitochondrial dynamics in the utrophin-dystrophin deficient mouse model of duchenne muscular dystrophy.

DMD UTRN

4.11e-06271225859846
Pubmed

G-utrophin, the autosomal homologue of dystrophin Dp116, is expressed in sensory ganglia and brain.

DMD UTRN

4.11e-0627127731967
Pubmed

Characterization of neuromuscular synapse function abnormalities in multiple Duchenne muscular dystrophy mouse models.

DMD UTRN

4.11e-06271227037492
Pubmed

Role of dystrophin and utrophin for assembly and function of the dystrophin glycoprotein complex in non-muscle tissue.

DMD UTRN

4.11e-06271216710609
Pubmed

Improvement in survival and muscle function in an mdx/utrn(-/-) double mutant mouse using a human retinal dystrophin transgene.

DMD UTRN

4.11e-06271216487708
Pubmed

Nonclinical Exon Skipping Studies with 2'-O-Methyl Phosphorothioate Antisense Oligonucleotides in mdx and mdx-utrn-/- Mice Inspired by Clinical Trial Results.

DMD UTRN

4.11e-06271230672725
Pubmed

Voltage-gated ion channel dysfunction precedes cardiomyopathy development in the dystrophic heart.

DMD UTRN

4.11e-06271221677768
Pubmed

Talin, vinculin and DRP (utrophin) concentrations are increased at mdx myotendinous junctions following onset of necrosis.

DMD UTRN

4.11e-0627127962191
Pubmed

Consequences of the combined deficiency in dystrophin and utrophin on the mechanical properties and myosin composition of some limb and respiratory muscles of the mouse.

DMD UTRN

4.11e-0627129713852
Pubmed

Skeletal muscle fibrosis in the mdx/utrn+/- mouse validates its suitability as a murine model of Duchenne muscular dystrophy.

DMD UTRN

4.11e-06271225607927
Pubmed

Does utrophin expression in muscles of mdx mice during postnatal development functionally compensate for dystrophin deficiency?

DMD UTRN

4.11e-0627128021701
Pubmed

Correlation of Utrophin Levels with the Dystrophin Protein Complex and Muscle Fibre Regeneration in Duchenne and Becker Muscular Dystrophy Muscle Biopsies.

DMD UTRN

4.11e-06271226974331
Pubmed

Developmental studies of dystrophin-positive fibers in mdx, and DRP localization.

DMD UTRN

4.11e-0627128433092
Pubmed

Second-generation compound for the modulation of utrophin in the therapy of DMD.

DMD UTRN

4.11e-06271225935002
Pubmed

Utrophin deficiency worsens cardiac contractile dysfunction present in dystrophin-deficient mdx mice.

DMD UTRN

4.11e-06271216024571
Pubmed

Androgen receptor agonists increase lean mass, improve cardiopulmonary functions and extend survival in preclinical models of Duchenne muscular dystrophy.

DMD UTRN

4.11e-06271228453658
Pubmed

A quantitative study of bioenergetics in skeletal muscle lacking utrophin and dystrophin.

DMD UTRN

4.11e-06271211801396
Pubmed

Apo-dystrophin-1 and apo-dystrophin-2, products of the Duchenne muscular dystrophy locus: expression during mouse embryogenesis and in cultured cell lines.

DMD UTRN

4.11e-0627127987307
Pubmed

Utility of dystrophin and utrophin staining in childhood muscular dystrophy.

DMD UTRN

4.11e-06271216295426
Pubmed

Comparative analysis of the human dystrophin and utrophin gene structures.

DMD UTRN

4.11e-06271211861579
Pubmed

Cyclin K regulates prereplicative complex assembly to promote mammalian cell proliferation.

CDK12 CCNK

4.11e-06271229760377
Pubmed

Distinct mechanical properties in homologous spectrin-like repeats of utrophin.

DMD UTRN

4.11e-06271230914715
Pubmed

Dystrophin is a microtubule-associated protein.

DMD UTRN

4.11e-06271219651889
Pubmed

Skeletal muscle-specific expression of a utrophin transgene rescues utrophin-dystrophin deficient mice.

DMD UTRN

4.11e-0627129590295
Pubmed

Comparison of skeletal muscle pathology and motor function of dystrophin and utrophin deficient mouse strains.

DMD UTRN

4.11e-06271222284942
Pubmed

Utrophin haploinsufficiency does not worsen the functional performance, resistance to eccentric contractions and force production of dystrophic mice.

DMD UTRN

4.11e-06271229879154
Pubmed

Haploinsufficiency of utrophin gene worsens skeletal muscle inflammation and fibrosis in mdx mice.

DMD UTRN

4.11e-06271217889902
Pubmed

Identification of Dp71 isoforms in the platelet membrane cytoskeleton. Potential role in thrombin-mediated platelet adhesion.

DMD UTRN

4.11e-06271212370193
Pubmed

Longitudinal metabolomic analysis of plasma enables modeling disease progression in Duchenne muscular dystrophy mouse models.

DMD UTRN

4.11e-06271232025735
Pubmed

Lifelong quercetin enrichment and cardioprotection in Mdx/Utrn+/- mice.

DMD UTRN

4.11e-06271227836895
Pubmed

BGP-15 Improves Aspects of the Dystrophic Pathology in mdx and dko Mice with Differing Efficacies in Heart and Skeletal Muscle.

DMD UTRN

4.11e-06271227750047
Pubmed

Prevention of dystrophin-deficient cardiomyopathy in twenty-one-month-old carrier mice by mosaic dystrophin expression or complementary dystrophin/utrophin expression.

DMD UTRN

4.11e-06271217967782
Pubmed

Diaphragm rescue alone prevents heart dysfunction in dystrophic mice.

DMD UTRN

4.11e-06271221062902
Pubmed

Matricellular Protein CCN5 Gene Transfer Ameliorates Cardiac and Skeletal Dysfunction in mdx/utrn (±) Haploinsufficient Mice by Reducing Fibrosis and Upregulating Utrophin Expression.

DMD UTRN

4.11e-06271235557546
Pubmed

Characterization of the Ang/Tie2 Signaling Pathway in the Diaphragm Muscle of DMD Mice.

DMD UTRN

4.11e-06271237626761
Pubmed

Molecular heterogeneity of the dystrophin-associated protein complex in the mouse kidney nephron: differential alterations in the absence of utrophin and dystrophin.

DMD UTRN

4.11e-06271215565469
Pubmed

The N- and C-Terminal Domains Differentially Contribute to the Structure and Function of Dystrophin and Utrophin Tandem Calponin-Homology Domains.

DMD UTRN

4.11e-06271226516677
Pubmed

Assessment of cardiac function in three mouse dystrophinopathies by magnetic resonance imaging.

DMD UTRN

4.11e-06271222209498
Pubmed

A Protocol for Simultaneous In Vivo Imaging of Cardiac and Neuroinflammation in Dystrophin-Deficient MDX Mice Using [18F]FEPPA PET.

DMD UTRN

4.11e-06271237108685
Pubmed

Prevention of the dystrophic phenotype in dystrophin/utrophin-deficient muscle following adenovirus-mediated transfer of a utrophin minigene.

DMD UTRN

4.11e-06271210694796
Pubmed

Dystrophin and dystrophin-related protein in the central nervous system of normal controls and Duchenne muscular dystrophy.

DMD UTRN

4.11e-0627128171962
Pubmed

Similar efficacy from specific and non-specific mineralocorticoid receptor antagonist treatment of muscular dystrophy mice.

DMD UTRN

4.11e-06271227822449
Pubmed

Micro-dystrophin gene therapy prevents heart failure in an improved Duchenne muscular dystrophy cardiomyopathy mouse model.

DMD UTRN

4.11e-06271233651713
Pubmed

Thermodynamic stability, unfolding kinetics, and aggregation of the N-terminal actin-binding domains of utrophin and dystrophin.

DMD UTRN

4.11e-06271222275054
Pubmed

NAD+ repletion improves muscle function in muscular dystrophy and counters global PARylation.

DMD UTRN

4.11e-06271227798264
Pubmed

Glycine administration attenuates progression of dystrophic pathology in prednisolone-treated dystrophin/utrophin null mice.

DMD UTRN

4.11e-06271231506484
Pubmed

Skeletal and cardiac myopathies in mice lacking utrophin and dystrophin: a model for Duchenne muscular dystrophy.

DMD UTRN

4.11e-0627129288752
Pubmed

Utrophin-dystrophin-deficient mice as a model for Duchenne muscular dystrophy.

DMD UTRN

4.11e-0627129288751
Pubmed

Enhanced currents through L-type calcium channels in cardiomyocytes disturb the electrophysiology of the dystrophic heart.

DMD UTRN

4.11e-06271224337461
Pubmed

Combined gene therapy via VEGF and mini-dystrophin synergistically improves pathologies in temporalis muscle of dystrophin/utrophin double knockout mice.

DMD UTRN

4.11e-06271233987645
Pubmed

Activation of calcineurin and stress activated protein kinase/p38-mitogen activated protein kinase in hearts of utrophin-dystrophin knockout mice.

DMD UTRN

4.11e-06271211297940
Pubmed

Utrophin up-regulation by artificial transcription factors induces muscle rescue and impacts the neuromuscular junction in mdx mice.

DMD UTRN

4.11e-06271229408646
InteractionSMC5 interactions

NOLC1 PRAM1 SMARCA5 ARID1B TAF3 CDK12 RBM19 BRD4 CD2AP ZNF280C KMT2A ZFR ADNP CHAMP1 DDX24 CCNK CIC MEF2D SLX4 RAI1 TASOR2 NDUFV3

1.42e-1210007022int:SMC5
InteractionACTC1 interactions

NOLC1 SMARCA5 ARID1B PHACTR2 CDK12 BRD4 PRIM2 CD2AP ZFR SORBS1 DMD ARHGAP35 ADNP UTRN CCNK CIC SLX4

1.59e-106947017int:ACTC1
InteractionTERF2IP interactions

TBC1D10A CDK12 BRD4 ZNF280C SMARCA1 KMT2A ADNP CHAMP1 DDX24 CIC MEF2D SLX4 RAI1 TASOR2

5.36e-095527014int:TERF2IP
InteractionNUP43 interactions

ARID1B TAF3 CDK12 RBM19 ZNF280C SMARCA1 KMT2A TMEM214 CHAMP1 DDX24 AHDC1 SLX4 PHF21A TASOR2

2.57e-086257014int:NUP43
InteractionNUMA1 interactions

SMARCA5 BRD4 ZNF280C SMARCA1 KMT2A ADNP MAP2K1 CHAMP1 DEPDC1B VARS1 SLX4 RAI1

6.87e-084697012int:NUMA1
InteractionFASLG interactions

KALRN PIK3R1 KMT2A OSTF1 DMD CLPX FYB1

7.79e-08105707int:FASLG
InteractionYWHAH interactions

MICALL1 NOLC1 PHLDB1 PHACTR2 BRD4 CD2AP KMT2A ARHGAP17 SORBS1 MAP2K1 FGD6 UTRN DEPDC1B RPH3A CIC MEF2D TP53BP2

1.55e-0711027017int:YWHAH
InteractionYWHAG interactions

MICALL1 NOLC1 SYNPO2 PHLDB1 PHACTR2 CDK12 PIK3R1 CD2AP KMT2A ARHGAP17 SORBS1 MAP2K1 FGD6 UTRN DEPDC1B CIC MEF2D TP53BP2

1.69e-0712487018int:YWHAG
InteractionNAA40 interactions

NOLC1 SMARCA5 CDK12 ZNF280C KMT2A ZFR ARHGAP35 ADNP CHAMP1 UTRN CCNK DEPDC1B AP3D1 CIC PHF21A TP53BP2

1.76e-079787016int:NAA40
InteractionRBPJ interactions

SMARCA5 CD40 SMARCA1 KMT2A ADNP DDX24 CIC MEF2D PHF21A

2.32e-07254709int:RBPJ
InteractionFBL interactions

NOLC1 SMARCA5 RBM19 BRD4 CD40 SMARCA1 ZFR CLPX MAP2K1 DDX24 AHDC1 CIC SLX4

2.61e-076397013int:FBL
InteractionCBX3 interactions

SMARCA5 CDK12 PIK3R1 BRD4 ZNF280C SMARCA1 KMT2A ADNP MAP2K1 CHAMP1 AHDC1 CIC SLX4

2.96e-076467013int:CBX3
InteractionH2BC9 interactions

H1-8 ZNF469 SMARCA5 PHACTR2 BRD4 PCLO SPAG17 FGD6 RAI1 TP53BP2 NDUFV3

3.69e-074467011int:H2BC9
InteractionSRC interactions

SMARCA5 PIK3R1 CD2AP SMARCA1 KMT2A ARHGAP17 TRPV4 OSTF1 SORBS1 ARHGAP35 MAP2K1 FYB1 CIC

4.04e-076647013int:SRC
InteractionFOXQ1 interactions

SMARCA5 SMARCA1 ZFR ADNP DDX24 VARS1 CIC

5.86e-07141707int:FOXQ1
InteractionHMGA1 interactions

SMARCA5 TAF3 BRD4 PCLO ZNF280C SMARCA1 KMT2A MAP2K1 CHAMP1 RAI1

1.77e-064197010int:HMGA1
InteractionSNRNP40 interactions

ARID1B CDK12 BRD4 PRIM2 ZNF280C SMARCA1 KMT2A DDX24 AHDC1 VARS1 PHF21A TASOR2

1.78e-066377012int:SNRNP40
InteractionPPIA interactions

PHLDB1 ARID1B TAF3 CDK12 ZNF280C DMD ARHGAP35 MAP2K1 CHAMP1 CCNK CIC MEF2D SLX4 TP53BP2

1.82e-068887014int:PPIA
InteractionKLF8 interactions

MICALL1 NOLC1 TAF3 CLPX ADNP DDX24 CIC MEF2D PHF21A

2.00e-06329709int:KLF8
InteractionNUP50 interactions

TAF3 GLB1 CDK12 BRD4 KMT2A ZFR CCNK SLX4 RAI1

2.68e-06341709int:NUP50
InteractionZNF330 interactions

NOLC1 SMARCA5 TAF3 RBM19 ZNF280C SMARCA1 KMT2A CLPX DDX24 RAI1

3.09e-064467010int:ZNF330
InteractionCHD4 interactions

NOLC1 SMARCA5 RBM19 BRD4 SMARCA1 KMT2A ZFR ADNP CHAMP1 DDX24 VARS1 CIC SLX4 RAI1

3.44e-069387014int:CHD4
InteractionKDM1A interactions

SMARCA5 BRD4 PRIM2 ANKEF1 CD2AP ZNF280C ADNP CHAMP1 UTRN VARS1 CIC MEF2D PHF21A TP53BP2

3.57e-069417014int:KDM1A
InteractionYAP1 interactions

SMARCA5 ARID1B TAF3 GLB1 CDK12 BRD4 CD2AP KMT2A ZFR ARHGAP35 ADNP MAP2K1 CHAMP1 CCNK TP53BP2

4.16e-0610957015int:YAP1
InteractionADNP interactions

BRD4 ADNP CHAMP1 AHDC1 VARS1 CIC SLX4

5.83e-06199707int:ADNP
InteractionUHRF2 interactions

NOLC1 SMARCA5 BRD4 KMT2A ADNP CHAMP1 TASOR2

6.03e-06200707int:UHRF2
InteractionAR interactions

SMARCA5 ARID1B PIK3R1 BRD4 KMT2A ZFR ADNP CHAMP1 CCNK AHDC1 CIC MEF2D PHF21A RAI1

6.55e-069927014int:AR
InteractionH3C3 interactions

SMARCA5 BRD4 ZNF280C SMARCA1 KMT2A ADNP CHAMP1 DDX24 CIC RAI1

7.73e-064957010int:H3C3
InteractionRPS6 interactions

NOLC1 H1-8 CDK12 RBM19 BRD4 PCLO ZFR MAP2K1 DDX24 VARS1 CIC SLX4 TP53BP2

8.41e-068747013int:RPS6
InteractionFOXE1 interactions

SMARCA5 SMARCA1 ZFR ADNP VARS1

9.13e-0681705int:FOXE1
InteractionH2AC4 interactions

SMARCA5 RBM19 BRD4 CD2AP KMT2A ZFR DDX24 VARS1 SLX4 RAI1

9.37e-065067010int:H2AC4
InteractionNUCKS1 interactions

SMARCA5 BRD4 ZNF280C SMARCA1 KMT2A CHAMP1 RAI1

1.12e-05220707int:NUCKS1
InteractionCHAMP1 interactions

BRD4 ADNP CHAMP1 AHDC1 CIC SLX4

1.26e-05148706int:CHAMP1
InteractionKLF3 interactions

SMARCA5 ARID1B TAF3 KMT2A CIC MEF2D PHF21A

1.42e-05228707int:KLF3
InteractionH1-4 interactions

NOLC1 PRAM1 SMARCA5 RBM19 BRD4 CD2AP KMT2A SPAG17 MAP2K1 DDX24 TASOR2

1.51e-056567011int:H1-4
InteractionHMGN5 interactions

SMARCA5 ZNF280C SMARCA1 KMT2A CHAMP1 RAI1

1.58e-05154706int:HMGN5
InteractionZBTB21 interactions

MICALL1 BRD4 FGD6 DEPDC1B CIC SLX4

2.04e-05161706int:ZBTB21
InteractionBCAR1 interactions

PRAM1 PIK3R1 BRD4 CD2AP RAPGEF1 OSTF1 DMD CHAMP1 FYB1 SLX4

2.11e-055567010int:BCAR1
InteractionSSRP1 interactions

NOLC1 SMARCA5 PIK3R1 BRD4 PRIM2 SMARCA1 KMT2A ZFR ADNP CIC RAI1

2.25e-056857011int:SSRP1
InteractionYWHAQ interactions

NOLC1 PHLDB1 PHACTR2 BRD4 KMT2A SORBS1 MAP2K1 DDX24 FGD6 CCNK VARS1 CIC MEF2D TP53BP2

2.52e-0511187014int:YWHAQ
InteractionH2BC21 interactions

SMARCA5 ARID1B BRD4 PCLO ZNF280C SMARCA1 KMT2A ADNP CHAMP1 FYB1 RAI1

2.61e-056967011int:H2BC21
InteractionRAD18 interactions

NOLC1 SMARCA5 CDK12 BRD4 SMARCA1 ZFR CHAMP1 UTRN CCNK

2.80e-05457709int:RAD18
InteractionMECP2 interactions

NOLC1 SMARCA5 ARID1B TAF3 KALRN CDK12 BRD4 ARHGAP35 ADNP CHAMP1 DDX24 CCNK AHDC1 VARS1 AP3D1

2.85e-0512877015int:MECP2
InteractionDAXX interactions

NOLC1 SMARCA5 ZNF280C ADNP CHAMP1 SLX4 RAI1 TASOR2

3.00e-05353708int:DAXX
InteractionSMARCA4 interactions

SMARCA5 ARID1B PIK3R1 BRD4 SMARCA1 ADNP DEPDC1B CIC SLX4

3.05e-05462709int:SMARCA4
InteractionMCAM interactions

MICALL1 PHLDB1 TBC1D10A SCARF2 ADGRB1 TRPV4 DMD UTRN DEPDC1B

3.37e-05468709int:MCAM
InteractionRNF2 interactions

NOLC1 SMARCA5 BRD4 PCLO KMT2A ZFR CLPX ADNP DDX24 CIC PHF21A CCNC

3.93e-058667012int:RNF2
InteractionCRK interactions

PIK3R1 BRD4 CD2AP RAPGEF1 ARHGAP17 PHF21A TP53BP2 TASOR2

4.19e-05370708int:CRK
InteractionH2AZ1 interactions

PLK2 SMARCA5 BRD4 ZNF280C SMARCA1 ADNP CHAMP1 RAI1

4.27e-05371708int:H2AZ1
InteractionPOLR1G interactions

NOLC1 TAF3 RBM19 BRD4 SMARCA1 KMT2A DDX24 CIC RAI1

4.74e-05489709int:POLR1G
InteractionCBLB interactions

PIK3R1 CD2AP OSTF1 SORBS1 FYB1

4.99e-05115705int:CBLB
InteractionZNF687 interactions

BRD4 DDX24 CIC SLX4 PHF21A

4.99e-05115705int:ZNF687
InteractionH3-3A interactions

SMARCA5 TAF3 BRD4 ZNF280C SMARCA1 KMT2A ADNP CHAMP1 VARS1 CIC RAI1

5.08e-057497011int:H3-3A
InteractionBRD3 interactions

NOLC1 SMARCA5 TAF3 BRD4 SMARCA1 KMT2A ADNP CHAMP1 RAI1

5.12e-05494709int:BRD3
InteractionSOS1 interactions

PIK3R1 CD2AP SORBS1 DMD ARHGAP35

5.42e-05117705int:SOS1
InteractionCHD8 interactions

BRD4 KMT2A AP3D1 CIC SLX4 PHF21A

5.62e-05193706int:CHD8
InteractionCBX1 interactions

BRD4 ZNF280C SMARCA1 ADNP MAP2K1 CHAMP1 AHDC1

6.29e-05288707int:CBX1
InteractionMLLT1 interactions

ARID1B CDK12 BRD4 KMT2A SLX4

6.88e-05123705int:MLLT1
InteractionH2BC3 interactions

SMARCA5 BRD4 KMT2A ZFR CHAMP1 DDX24 UTRN RAI1

8.03e-05406708int:H2BC3
InteractionCEBPA interactions

NOLC1 PRAM1 ARID1B BRD4 KMT2A ZFR ADNP CCNK AHDC1 VARS1 CIC MEF2D PHF21A RAI1

8.12e-0512457014int:CEBPA
InteractionYWHAE interactions

MICALL1 NOLC1 PHLDB1 CDK12 PIK3R1 BRD4 KMT2A SORBS1 MAP2K1 DDX24 FGD6 DEPDC1B CIC TP53BP2

8.93e-0512567014int:YWHAE
InteractionAGAP2 interactions

KALRN PIK3R1 PCLO SORBS1 MAP2K1 TP53BP2

8.97e-05210706int:AGAP2
InteractionKSR1 interactions

MICALL1 CDK12 MAP2K1 FGD6 DEPDC1B

9.61e-05132705int:KSR1
InteractionSNTG2 interactions

ADGRB1 DMD UTRN

9.85e-0526703int:SNTG2
InteractionHDAC1 interactions

NOLC1 SMARCA5 BRD4 CD2AP KMT2A ADNP UTRN VARS1 CIC MEF2D PHF21A RAI1 TP53BP2

9.94e-0511087013int:HDAC1
InteractionCD2AP interactions

MICALL1 NOLC1 PIK3R1 CD2AP ARHGAP17 SORBS1

9.95e-05214706int:CD2AP
InteractionIK interactions

NOLC1 SMARCA5 CDK12 BRD4 CIC SLX4

1.02e-04215706int:IK
InteractionWWTR1 interactions

SMARCA5 ARID1B CDK12 BRD4 CD2AP KMT2A ADNP TP53BP2

1.05e-04422708int:WWTR1
InteractionNUP35 interactions

ARID1B CDK12 ZFR TMEM214 AHDC1 CIC MEF2D RAI1

1.08e-04424708int:NUP35
InteractionSH3KBP1 interactions

MICALL1 PHLDB1 PIK3R1 CD2AP ARHGAP17 RPH3A TP53BP2

1.10e-04315707int:SH3KBP1
InteractionBRD2 interactions

NOLC1 SMARCA5 TAF3 BRD4 SMARCA1 TMEM214 DDX24 SLX4

1.18e-04429708int:BRD2
InteractionHMGN2 interactions

CDK12 BRD4 PCLO ZNF280C CLPX UTRN

1.22e-04222706int:HMGN2
InteractionERG interactions

NOLC1 ARID1B BRD4 CIC MEF2D SLX4

1.25e-04223706int:ERG
InteractionH2BC12 interactions

NOLC1 BRD4 PCLO KMT2A SPAG17 AP3D1 CIC

1.26e-04322707int:H2BC12
InteractionTOP3B interactions

MICALL1 PHLDB1 KALRN CDK12 RBM19 BRD4 RAPGEF1 ARHGAP17 ZFR ARHGAP35 CLPX AHDC1 AP3D1 CIC RAI1

1.29e-0414707015int:TOP3B
InteractionFOXK2 interactions

SMARCA5 BRD4 SMARCA1 ADNP CIC MEF2D

1.31e-04225706int:FOXK2
InteractionTOP1 interactions

SMARCA5 BRD4 PRIM2 SMARCA1 KMT2A ZFR ADNP CHAMP1 DDX24 RAI1

1.38e-046967010int:TOP1
InteractionYWHAZ interactions

MICALL1 NOLC1 SYNPO2 PHLDB1 PIK3R1 BRD4 KMT2A SORBS1 MAP2K1 DDX24 FGD6 DEPDC1B CIC TP53BP2

1.50e-0413197014int:YWHAZ
InteractionH3-4 interactions

TAF3 KMT2A THSD7B DMD ADNP CHAMP1 AHDC1 PHF21A

1.58e-04448708int:H3-4
InteractionPOLD1 interactions

NOLC1 TAF3 BRD4 PRIM2 SMARCA1 ARHGAP25 CIC

1.67e-04337707int:POLD1
InteractionARRB2 interactions

NOLC1 BRD4 ADGRB1 ARHGAP17 TRPV4 MAP2K1 AP3D1 PHF21A

1.73e-04454708int:ARRB2
InteractionMGA interactions

BRD4 ADNP CHAMP1 CIC SLX4 PHF21A

1.86e-04240706int:MGA
InteractionLCK interactions

NOLC1 KALRN PIK3R1 ARHGAP17 TRPV4 UTRN VARS1 AP3D1

1.98e-04463708int:LCK
InteractionMEN1 interactions

NOLC1 SMARCA5 ARID1B KMT2A ZFR ADNP CHAMP1 DDX24 CCNK AHDC1 AP3D1 MEF2D

2.02e-0410297012int:MEN1
InteractionSMARCC2 interactions

SMARCA5 ARID1B PIK3R1 BRD4 SMARCA1 KMT2A ADNP

2.22e-04353707int:SMARCC2
InteractionCHAF1B interactions

BRD4 SMARCA1 ADNP CHAMP1 CIC

2.23e-04158705int:CHAF1B
InteractionFOXS1 interactions

SMARCA5 GLB1 ZFR ADNP

2.29e-0486704int:FOXS1
InteractionH3C1 interactions

SMARCA5 TAF3 BRD4 ZNF280C SMARCA1 KMT2A ZFR CLPX ADNP CHAMP1 DDX24

2.59e-049017011int:H3C1
InteractionH1-0 interactions

SMARCA5 BRD4 SMARCA1 MAP2K1 SLX4 RAI1

2.63e-04256706int:H1-0
InteractionFGFBP1 interactions

SMARCA5 CDK12 RBM19 KMT2A ZFR DDX24

2.69e-04257706int:FGFBP1
InteractionH2BC4 interactions

NOLC1 BRD4 KMT2A SPAG17 AP3D1 TP53BP2

2.80e-04259706int:H2BC4
InteractionSAP30 interactions

SMARCA5 BRD4 SMARCA1 KMT2A CIC

2.88e-04167705int:SAP30
InteractionSRGAP1 interactions

CD2AP SORBS1 DMD ARHGAP35

2.96e-0492704int:SRGAP1
InteractionCSNK2B interactions

NOLC1 SMARCA5 GLB1 BRD4 KMT2A ADNP DDX24 CIC TP53BP2

3.02e-04625709int:CSNK2B
InteractionRCOR1 interactions

SMARCA5 BRD4 CD2AP UTRN VARS1 CIC PHF21A TP53BP2

3.07e-04494708int:RCOR1
InteractionGATA1 interactions

SMARCA5 ARID1B BRD4 ZFR RAI1

3.22e-04171705int:GATA1
InteractionPLEKHA2 interactions

BRD4 DMD ARHGAP35 UTRN

3.22e-0494704int:PLEKHA2
InteractionXRCC6 interactions

SMARCA5 CDK12 BRD4 ZNF280C CD40 KMT2A ZFR ADNP CHAMP1 CCNK CIC

3.34e-049287011int:XRCC6
InteractionFOXG1 interactions

SMARCA5 SMARCA1 ADNP VARS1

3.35e-0495704int:FOXG1
InteractionZMYM2 interactions

ZNF280C ADNP CHAMP1 CIC SLX4 PHF21A

3.57e-04271706int:ZMYM2
Cytoband10p15.1

TAF3 TASOR2

8.68e-042871210p15.1
GeneFamilyRho GTPase activating proteins|BCH domain containing

ARHGAP17 ARHGAP25 ARHGAP35

2.78e-0450463721
GeneFamilyZinc fingers ZZ-type|Lysine acetyltransferases

DMD UTRN

9.44e-041846291
GeneFamilyPHD finger proteins

TAF3 KMT2A PHF21A

1.55e-039046388
GeneFamilyCyclins

CCNK CCNC

2.30e-0328462473
GeneFamilyAnkyrin repeat domain containing

ANKEF1 TRPV4 OSTF1 TP53BP2

3.29e-03242464403
GeneFamilyGATA zinc finger domain containing|Myb/SANT domain containing

SMARCA5 SMARCA1

8.04e-0353462532
GeneFamilyPleckstrin homology domain containing|Rho guanine nucleotide exchange factors|C2 domain containing

KALRN FGD6

1.22e-0266462722
CoexpressionGSE9037_WT_VS_IRAK4_KO_BMDM_UP

ZNF469 SYNPO2 SMARCA5 CDK12 CD2AP ZNF280C DMD

1.19e-06200717M5812
CoexpressionDACOSTA_UV_RESPONSE_VIA_ERCC3_DN

SMARCA5 PRIM2 CD2AP GLRB SMARCA1 DMD ARHGAP35 ADNP MAP2K1 AHDC1 PHF21A TP53BP2

2.97e-068567112M4500
CoexpressionGSE15330_HSC_VS_LYMPHOID_PRIMED_MULTIPOTENT_PROGENITOR_IKAROS_KO_DN

NOLC1 SMARCA5 PHLDB1 KMT2A UTRN MEF2D

1.64e-05198716M7035
ToppCellControl-Fibroblasts-Airway_smooth_muscle|Control / group, cell type (main and fine annotations)

SYNPO2 CPXM2 KALRN SORBS1 THSD7B DMD

4.35e-07180716d0de12749ef0f51f0931c6e7b9b99966bdbc3ec1
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell-|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

SYNPO2 KALRN ARHGAP17 SORBS1 DMD MEF2D

6.35e-07192716bfab13793e54de2550ee171397f7ece0625cdb4a
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

SYNPO2 KALRN ARHGAP17 SORBS1 DMD MEF2D

6.35e-07192716b54b0d5b88139905521c8d5d58332e89c08d589c
ToppCellmild|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

SMARCA5 ARID1B PIK3R1 KMT2A DDX24 UTRN

8.06e-0720071612f1685ce8f218433068e090c9d839cd5a1910bf
ToppCellPND01-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_airway-ASMC-ASMC_mature|PND01 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

SYNPO2 MYL4 CPXM2 CEND1 DEPDC1B

6.88e-06166715390cf5e56b72fcaf3b8520930bd35a3e3e173711
ToppCellPND01-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_airway-ASMC|PND01 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

SYNPO2 MYL4 CPXM2 CEND1 DEPDC1B

6.88e-061667159a341dc7b756252caeaac1e934384911c880a634
ToppCellAdult-Mesenchymal-airway_smooth_muscle_cell|Adult / Lineage, Cell type, age group and donor

SYNPO2 KALRN SORBS1 THSD7B DMD

8.41e-06173715a5331721bd9f9a66530dd4ffe28cb3a5a8cad8fc
ToppCellnucseq-Mesenchymal-Fibroblastic-Fibroblastic_2-ASMC|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

SYNPO2 CPXM2 KALRN SORBS1 DMD

8.41e-06173715cb6389536195443633adb06e5f1b7483530773d1
ToppCell3'-Child09-12-SmallIntestine-Mesenchymal-myocytic-myofibroblast_(RSPO2+)|Child09-12 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

SYNPO2 CPXM2 GLRB SORBS1 DMD

9.14e-06176715a8875b4ba4abf6625cdeb67bf544ce1573c59060
ToppCell3'-GW_trimst-2-LargeIntestine-Mesenchymal-myocytic-SMC_(PLPP2+)|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

SYNPO2 MYL4 CPXM2 SORBS1 DMD

9.92e-06179715e860dca9b28ac5af61804bfd729cd39257cdb352
ToppCell18-Airway-Epithelial-Submucosal_gland_basal|Airway / Age, Tissue, Lineage and Cell class

MICALL1 PLK2 SYNPO2 ADGRB1 THSD7B

1.05e-0518171533938e6521712058312879f84f4ae381c2bfc379
ToppCellAdult-Mesenchymal-airway_smooth_muscle_cell-D175|Adult / Lineage, Cell type, age group and donor

SYNPO2 KALRN CD40 SORBS1 THSD7B

1.08e-05182715ad4d74d8b19976e1ccc3c5ba8013199338cf6fd8
ToppCellRA-13._Vascular_Smooth_Muscle|RA / Chamber and Cluster_Paper

SYNPO2 CPXM2 KALRN SORBS1 DMD

1.10e-05183715818fd886e0188091310825f9145fa53328f2c979
ToppCellRA-13._Vascular_Smooth_Muscle|World / Chamber and Cluster_Paper

SYNPO2 CPXM2 KALRN SORBS1 DMD

1.10e-05183715cae2ee08f985a6f005b4b8e959e465350315156a
ToppCell10x5'-GI_small-bowel-Lymphocytic_T_CD4-T_CD4/CD8|GI_small-bowel / Manually curated celltypes from each tissue

ARID1B KMT2A UTRN TP53BP2 TASOR2

1.26e-05188715ab9b725d6e0cdab8e9ddda6dee09e14730e9a578
ToppCellLA-13._Vascular_Smooth_Muscle|LA / Chamber and Cluster_Paper

SYNPO2 CPXM2 KALRN SORBS1 DMD

1.26e-0518871534e1b074a3995aa46ab194eb45115d76d1a5514d
ToppCellLA-13._Vascular_Smooth_Muscle|World / Chamber and Cluster_Paper

SYNPO2 CPXM2 KALRN SORBS1 DMD

1.29e-051897156b3e88751b95fc2173f2c3d5061ed632d0c5f01c
ToppCell3'-GW_trimst-1.5-LargeIntestine-Mesenchymal-myocytic|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

SYNPO2 CPXM2 GLRB SORBS1 DMD

1.36e-05191715de2cd94ee88a7754f86d39469e38374d668210c7
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Mesenchymal-Myocytic_interstitial_cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

SYNPO2 KALRN SORBS1 DMD UTRN

1.36e-0519171504c4d454b57e29a8d1dcdeb4678ce71bdc29b77b
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell_/_Pericyte|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

SYNPO2 KALRN ARHGAP17 DMD UTRN

1.36e-051917157b0d42a877540dbb346a76a62403e0d5d3e07fa6
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell_/_Pericyte-|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

SYNPO2 KALRN ARHGAP17 DMD UTRN

1.36e-05191715cd854b9c426924fdc84bf7f411f6dea447143e79
ToppCelldroplet-Heart-HEART_(LV+RV_ONLY)-30m-Mesenchymal-smooth_muscle_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SYNPO2 CPXM2 KALRN SMARCA1 CEND1

1.43e-051937150266a4fdf436d83ec1d9392abba8c6ec5166970a
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Myocytic_interstitial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

SYNPO2 KALRN SORBS1 DMD UTRN

1.46e-05194715ebb038f94f49f5c655578d1b018676e10c6b7e3c
ToppCellfacs-Heart-RA-18m-Endothelial|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PLK2 PHACTR2 RAPGEF1 SORBS1 UTRN

1.50e-0519571530c75761079fa1e1a3b84d23c88a222f459d5ce5
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Myocytic_interstitial_cell-Myofibroblast|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

SYNPO2 CPXM2 KALRN SORBS1 DMD

1.54e-051967151522958a92e0126326a9f0d9fb1c5b5c50b001ea
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Mesenchymal-Myocytic_interstitial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

SYNPO2 KALRN SORBS1 DMD UTRN

1.54e-05196715b8759e6231e0254797d6c30930407b79440c57bb
ToppCellPBMC_fresh-frozen-Severe-critical_progression_d12-22_no-steroids-Lymphocytic|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)

ARID1B CD40 KMT2A ARHGAP25 DDX24

1.54e-05196715c225c8eb2fe9a10f0cf574c7d8b6206887aac2df
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Myocytic_interstitial_cell-Myofibroblast-|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

SYNPO2 CPXM2 KALRN SORBS1 DMD

1.54e-051967151c8294014713684b50885e638668f2ce75f357f0
ToppCellBronchial-NucSeq-Stromal-Myofibroblastic-Muscle_smooth_pulmonary|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

SYNPO2 CPXM2 KALRN SORBS1 DMD

1.58e-05197715bf0520a94ebb1d2f94de9f526d17e0b0e8fe7052
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Mesenchymal|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

SYNPO2 KALRN SORBS1 DMD UTRN

1.58e-051977159b480f9c799a244bfee64487abd8a1bf07c9a3a2
ToppCell(11)_FOXN4+-(2)_GFP_FOXI1|(11)_FOXN4+ / shred by cell type by condition

PHACTR2 TAF3 BRD4 CD2AP UTRN

1.61e-0519871576d40b8c2f8399725b3a62ee2ae0896559cf91eb
ToppCell(10)_Ciliated-(2)_GFP_FOXI1|(10)_Ciliated / shred by cell type by condition

BRD4 CD2AP ZFR SPAG17 AP3D1

1.65e-0519971561b1ed2db71b96157b92b7535d1955a4033098da
ToppCellmild-MAIT|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

PHACTR2 PIK3R1 CD2AP DDX24 UTRN

1.65e-05199715cbe1fb6d2c5fca7a1baf1ad20afcdf8e8e11bd84
ToppCell(03)_KRT6B+-(2)_GFP_FOXI1|(03)_KRT6B+ / shred by cell type by condition

PHACTR2 PIK3R1 BRD4 PCLO UTRN

1.65e-05199715c425e7975f492ed5cfcca022248adb627e1d27d4
ToppCell(05)_Secretory-(2)_GFP_FOXI1|(05)_Secretory / shred by cell type by condition

PHACTR2 TAF3 BRD4 CD2AP AP3D1

1.65e-05199715d72d87e1e530ed894c0ad5e7b5b2b1d6b59fa098
ToppCellStriatum-Neuronal|Striatum / BrainAtlas - Mouse McCarroll V32

PCLO DDX24 RPH3A AP3D1 GABRA2

1.69e-05200715c888fd487990cad482a4ca47601cdebc0ca3f3ce
ToppCellBronchial-NucSeq-Stromal-Myofibroblastic|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

SYNPO2 CPXM2 KALRN SORBS1 DMD

1.69e-05200715a66449b22b39dd6987fc2c3ed160d24564234ced
ToppCellCOVID-19|World / Disease, condition lineage and cell class

ARID1B PIK3R1 KMT2A DDX24 UTRN

1.69e-052007157dec470c379cd89f05a0f37c8628b21f136e52f0
ToppCelldroplet-Trachea-nan-3m-Mesenchymal-mesenchymal_cell|Trachea / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CPXM2 SCARF2 PIK3R1 ANKEF1

4.93e-05126714c3261ea8726400de87f1c8a5a5134ba2b2884f66
ToppCellChildren_(3_yrs)-Mesenchymal-airway_smooth_muscle_cell-D139|Children_(3_yrs) / Lineage, Cell type, age group and donor

SYNPO2 CPXM2 PIK3R1 DMD

1.05e-041537141524557514668f515ac1bbe847611f564b265b42
ToppCellTCGA-Bone_and_Soft_Tissue-Primary_Tumor-Sarcoma-Conventional_Leiomyosarcoma|TCGA-Bone_and_Soft_Tissue / Sample_Type by Project: Shred V9

SYNPO2 KALRN SORBS1 DMD

1.05e-04153714ec6fe6b8c884fa76adc7a0f9db041f7b1567a2ee
ToppCellLPS-IL1RA+antiTNF-Epithelial_airway-Ciliated_cells|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

IQCH ANKEF1 TRPV4 SPAG17

1.10e-041557145f1e2195a6b831e1b636f5cc3a282ca423721822
ToppCellLPS-IL1RA+antiTNF-Epithelial_airway-Ciliated_cells-Ciliated|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

IQCH ANKEF1 TRPV4 SPAG17

1.10e-041557140944429459f642a1bcc56edc1ec28aaecde3e2dc
ToppCellAdult-Mesenchymal-airway_smooth_muscle_cell-D122|Adult / Lineage, Cell type, age group and donor

SYNPO2 KALRN SORBS1 DMD

1.27e-0416171464891f6f2ee1693c8481e951b9346e2f92d602e3
ToppCellFetal_brain-fetalBrain_Zhong_nature-GW16-Neuronal-GABAergic_neurons|GW16 / Sample Type, Dataset, Time_group, and Cell type.

SYNPO2 THSD7B RPH3A GABRA2

1.37e-041647144d7b2d0980fb4f47721fa2891151e2bd892ccb91
ToppCellLV-13._Vascular_Smooth_Muscle|World / Chamber and Cluster_Paper

SYNPO2 KALRN DMD UTRN

1.40e-04165714f37fd95adc95d7753cf6e55ae819976513c7ec77
ToppCellPND28-Mesenchymal-Mesenchymal_structural-Fibroblastic-Chondrocyte-Chondrocyte_mature|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

CPXM2 TBC1D10A SMARCA1 AHDC1

1.43e-0416671437794a84601a2a949d579663d4a4bb8bc8fb5923
ToppCellPND28-Mesenchymal-Mesenchymal_structural-Fibroblastic-Chondrocyte|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

CPXM2 TBC1D10A SMARCA1 AHDC1

1.43e-0416671481c546c6d847e49e662b81e71992ca0f7a99e890
ToppCell10x_3'_v2v3-Non-neoplastic-Myeloid-DC-DC1-B|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

ZNF469 CPXM2 CD2AP ZNF280C

1.43e-04166714c8a7d94ed762e5e045ab5f74eef691ddc5f74993
ToppCellAdult-Mesenchymal-vascular_smooth_muscle_cell|Adult / Lineage, Cell type, age group and donor

SYNPO2 KALRN SORBS1 DMD

1.64e-04172714c62cad0f4212d1e9ea1ec3143ad3c4e06aff0ebf
ToppCellChildren_(3_yrs)-Mesenchymal-vascular_smooth_muscle_cell|Children_(3_yrs) / Lineage, Cell type, age group and donor

SYNPO2 KALRN SORBS1 DMD

1.68e-041737145416b092321c7d9b63f0418c60f2402a138355bf
ToppCellCOVID-19-Heart-VSMC|COVID-19 / Disease (COVID-19 only), tissue and cell type

SYNPO2 KALRN SORBS1 DMD

1.75e-041757141125f0d3a5b2388fa77a820dea0288e824d84a82
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

KALRN SORBS1 DMD UTRN

1.75e-04175714316f2ea930437bf1243b1c0f45e6bd864112c6f2
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell-|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

KALRN SORBS1 DMD UTRN

1.75e-04175714a9f08e1e4c2997dcdd3e5d92daac480da19100b8
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Mesenchymal-Myocytic_interstitial_cell-Myofibroblast-|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

SYNPO2 KALRN SORBS1 DMD

1.79e-041767149bc87cd5cda2372e1bce94c9dfd408eb1dfd8d0c
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Mesenchymal-Myocytic_interstitial_cell-Myofibroblast|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

SYNPO2 KALRN SORBS1 DMD

1.79e-041767143f8274a7ab67f9f8a8923193763a5543cfe4defa
ToppCellPND03-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_airway-ASMC|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

SYNPO2 MYL4 CPXM2 DMD

1.83e-04177714c9b02a2e1ff2aa18c37e88a53b06a5b696a442ae
ToppCell5'-Adult-Appendix-Mesenchymal-myocytic-myofibroblast|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

SYNPO2 PHACTR2 SORBS1 DMD

1.83e-04177714e65c0568dc5852108e9802273499bc7cf88fafab
ToppCellChildren_(3_yrs)-Mesenchymal-airway_smooth_muscle_cell|Children_(3_yrs) / Lineage, Cell type, age group and donor

SYNPO2 SORBS1 THSD7B DMD

1.83e-04177714b59967219f7d874805768e247c0eb2bc4d4420c8
ToppCelldroplet-Limb_Muscle-MUSCLE-30m|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SMARCA5 CDK12 CD2AP UTRN

1.87e-0417871401dafd19de04eff459253eaa9a35debf8f3deedf
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast-kidney_interstitial_fibroblast_5|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

SYNPO2 KALRN SORBS1 DMD

1.87e-04178714d4ecb84e9b1f4ec49c519321156aa10f9bd34cce
ToppCellFF-Differ-KC|World / shred by cell class for mouse tongue

PHLDB1 SCARF2 PCLO SORBS1

1.91e-041797141526a130565a97c291a25a7a988089bffc1515c1
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell-Distal_Convoluted_Tubule_Cell_Type_2|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

CPXM2 THSD7B DEPDC1B GABRA2

1.91e-04179714666072c0e8448dbaec1683d18368ec2502453f90
ToppCellRSV-Healthy-0|RSV / Virus stimulation, Condition and Cluster

CEND1 ADNP FYB1 UTRN

1.95e-04180714974044056e2f7e909cb11c6f6ca89e58bf95f7e5
ToppCell5'-Parenchyma_lung-Endothelial-Blood_vessel_EC-vein_endothelial_cell-EC_venous_pulmonary-EC_venous_pulmonary_L.2.2.1.1|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

IQCH CPXM2 ZNF280C DEPDC1B

1.95e-0418071440d4838a0ccb10d5e49266bc8a0037d27b75ccc2
ToppCellRSV-Healthy-0|Healthy / Virus stimulation, Condition and Cluster

CEND1 ADNP FYB1 UTRN

1.95e-04180714703a1d0f9536af94d56757eb01221878d7b7fe61
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell-Outer_Medullary_Collecting_Duct_Principal_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

CD2AP TRPV4 SPAG17 GABRA2

1.99e-04181714aa233b652921848af2257cc3687a7a09c3acfb67
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast-Collagen+matrisome-high_fibroblast|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

SYNPO2 KALRN SORBS1 DMD

2.04e-0418271444764676ed3f51ba171ce63f669390392fa50a43
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast-Collagen+matrisome-high_fibroblast-|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

SYNPO2 KALRN SORBS1 DMD

2.04e-04182714d82f59a3f930a840dde27dc6ab024f227a26d446
ToppCellCOVID-19_Mild-gd_T|COVID-19_Mild / Disease condition and Cell class

PIK3R1 RAPGEF1 ARHGAP25 UTRN

2.08e-04183714f593a89b0aa8fffdfa403769916facfd30358521
ToppCellCalu_3-infected|Calu_3 / Cell line, Condition and Strain

CDK12 CD2AP FGD6 UTRN

2.08e-041837148f7f5000645f24f20a8d7700c4df1f8953a1780b
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic-thymocyte|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

KALRN PCLO DMD SPAG17

2.12e-041847142cbed6462fea2622871bb7e49b0df3d984239281
ToppCelldroplet-Lung-30m-Mesenchymal-myofibroblast|30m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

SCARF2 SMARCA1 CEND1 DMD

2.12e-0418471455dde9c4eebac2a33788c1ff1d8fe312d150fad4
ToppCelldroplet-Marrow-nan-3m|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SMARCA5 CD2AP KMT2A UTRN

2.12e-041847141154a5ad7b8512272b7476f949ddac350910bfb7
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

KALRN PCLO DMD SPAG17

2.12e-04184714ea7a7e2bac46d4d2c31a5d576b38a032b5335062
ToppCelldroplet-Lung-30m-Mesenchymal-myofibroblast-pericyte_cell-pericyte|30m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

SCARF2 SMARCA1 CEND1 DMD

2.12e-041847147128a2be291544d3df3ed6c80f21ddda8437dcba
ToppCelldroplet-Lung-30m-Mesenchymal-myofibroblast-pericyte_cell|30m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

SCARF2 SMARCA1 CEND1 DMD

2.12e-04184714d14238f7b0b55a4c8d7040bea854bd221a66ac30
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic-proliferating_thymocyte;_DN_to_DP_transition,_dividing_(some_are_Cd8+/_Cd4+,_some_undergoing_VDJ_recombination)|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

KALRN PCLO DMD SPAG17

2.12e-041847142b19a8c5f823e00812908b23e66bb4e563278aff
ToppCell3'-Child09-12-SmallIntestine-Mesenchymal-myocytic|Child09-12 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

SYNPO2 MYL4 SORBS1 DMD

2.12e-041847145cfc19ffb9f074bdf0d81c86e212a708ec141631
ToppCelldroplet-Bladder-nan|Bladder / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SMARCA5 TAF3 CDK12 DDX24

2.26e-04187714663991a8afe652e92363b64bcbd68c14d0307f0e
ToppCellCOVID-19-Fibroblasts-Airway_smooth_muscle|COVID-19 / group, cell type (main and fine annotations)

SYNPO2 KALRN SORBS1 DMD

2.26e-04187714464a0c3b92b778911b5f9cd73642e09e3472063a
ToppCellCOVID-19-kidney-Fibroblast-1|COVID-19 / Disease (COVID-19 only), tissue and cell type

SYNPO2 KALRN SORBS1 DMD

2.26e-0418771476bfe8c42430a230a8bdf299575c444fb7780f24
ToppCell5'-GW_trimst-2-LargeIntestine-Mesenchymal-myocytic-SMC_(PLPP2+)|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

SYNPO2 CPXM2 SORBS1 DMD

2.26e-041877143912bbb610a4a84791e9bda92a2d57a52c31d29e
ToppCellTCGA-Breast-Primary_Tumor-Breast_Carcinoma-Infiltrating_Lobular_Carcinoma-6|TCGA-Breast / Sample_Type by Project: Shred V9

SCARF2 THSD7B CIC MEF2D

2.31e-04188714c90669b51e1902fe7726555290c91c92a911df83
ToppCelldroplet-Heart-HEART_(ALL_MINUS_AORTA)-30m-Mesenchymal-smooth_muscle_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SYNPO2 KALRN SMARCA1 CEND1

2.35e-04189714de51fbd6fdb24fc4549393cf41a020005444b2aa
ToppCellfacs-Heart-RA-18m-Endothelial-coronary_vascular_endothelial_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PLK2 RAPGEF1 SORBS1 UTRN

2.35e-041897141be5067c1e45af7d09c1fd6955952cb9e031a3a0
ToppCellfacs-Heart-RA-18m-Endothelial-endothelial_cell_of_coronary_artery|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PLK2 RAPGEF1 SORBS1 UTRN

2.35e-0418971430dc1725d43a60017fb12d706f1f85a33de4947e
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Mesenchymal-Myocytic_interstitial_cell-Myofibroblast-|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

SYNPO2 CPXM2 SORBS1 DMD

2.40e-041907142e88e366d377d74deb53a4ea870973ce5c6532e8
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Mesenchymal-Fibroblast-Collagen-low_Matrisome-low_fibroblast-|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

SYNPO2 KALRN SORBS1 DMD

2.40e-041907141121eb607a984c59fbffe7220837fc178745aa55
ToppCell3'-GW_trimst-1.5-LargeIntestine-Mesenchymal-myocytic-SMC_(PLPP2+)|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

SYNPO2 CPXM2 SORBS1 DMD

2.40e-04190714e102622f05c7f3e1bd8b224ea159d57033793ee0
ToppCellCOVID-19-Heart|COVID-19 / Disease (COVID-19 only), tissue and cell type

SYNPO2 KALRN SORBS1 DMD

2.40e-04190714918ad5037881212008f9f69d5df5da91fd01422c
ToppCellMesenchymal-airway_smooth_muscle_cell|World / Lineage, Cell type, age group and donor

SYNPO2 PHLDB1 SORBS1 THSD7B

2.40e-04190714645e56b02edc3702c7db917b8ecd5eed0decaf71
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Mesenchymal-Fibroblast-Collagen-low_Matrisome-low_fibroblast|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

SYNPO2 KALRN SORBS1 DMD

2.40e-04190714048b581e3f7ea9fc2f87c0532974bba85c7292c2
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Mesenchymal-Myocytic_interstitial_cell-Myofibroblast-|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

SYNPO2 CPXM2 SORBS1 DMD

2.40e-04190714562ee3b025c29edf07b8b344323edb49d82f1c7e
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Mesenchymal-Myocytic_interstitial_cell-Myofibroblast|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

SYNPO2 CPXM2 SORBS1 DMD

2.40e-041907140028f886c789ba238c031eae5d96acaed4af8c25
ToppCellChildren_(3_yrs)-Endothelial-alveolar_capillary_endothelial_cell_(Cap2;_aerocyte)-D139|Children_(3_yrs) / Lineage, Cell type, age group and donor

SYNPO2 PHLDB1 KALRN SORBS1

2.40e-041907140a351609a72fd638c84b2435782e312ee6a33aac
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Mesenchymal-Myocytic_interstitial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

SYNPO2 CPXM2 SORBS1 DMD

2.40e-041907145681c211baeed4af82a2bbc13420f6a7b487581c
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Myocytic_interstitial_cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

SYNPO2 KALRN SORBS1 DMD

2.40e-0419071470c86dd454afb21d4a85db56c5f369d4b342bc97
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Mesenchymal-Myocytic_interstitial_cell-Myofibroblast|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

SYNPO2 CPXM2 SORBS1 DMD

2.40e-04190714f5fb989afabb49d64d91324570cd8c80a4b9e67d
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-Collagen+matrisome-high_fibroblast|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

SYNPO2 KALRN SORBS1 DMD

2.45e-04191714a6c57627077fa980b7ec1d3894b5f31bfb11b738
DrugNeostigmine bromide [114-80-7]; Down 200; 13.2uM; PC3; HT_HG-U133A

NOLC1 PHACTR2 PCLO KMT2A ZFR DDX24 UTRN

1.99e-061887176735_DN
DrugICI 182,780; Down 200; 1uM; MCF7; HT_HG-U133A_EA

PHACTR2 PIK3R1 BRD4 KMT2A DDX24 AP3D1

1.91e-05177716985_DN
DrugEtifenin [63245-28-3]; Down 200; 12.4uM; PC3; HT_HG-U133A

PHACTR2 PCLO KMT2A ZFR DDX24 AP3D1

1.97e-051787163998_DN
Drug3,5,3',4',5'-pentahydroxy-stilbene

PIK3R1 MAP2K1

2.87e-053712ctd:C473468
DrugPempidine tartrate [546-48-5]; Down 200; 13uM; MCF7; HT_HG-U133A

PHACTR2 PIK3R1 KMT2A ARHGAP35 CCNK AP3D1

2.93e-051917163926_DN
DrugH-89, Dihydrochloride; Up 200; 0.5uM; PC3; HT_HG-U133A

SMARCA5 PHACTR2 PCLO GLRB KMT2A ZFR

3.20e-051947166921_UP
Drug(R)-(+)-Atenolol [56715-13-0]; Up 200; 15uM; MCF7; HT_HG-U133A

RBM19 BRD4 KMT2A ARHGAP35 UTRN MEF2D

3.30e-051957162855_UP
DrugCefepime hydrochloride [123171-59-5]; Down 200; 7.4uM; HL60; HT_HG-U133A

KMT2A ZFR ARHGAP35 FYB1 DDX24 AP3D1

3.30e-051957166159_DN
DrugEstropipate [7280-37-7]; Down 200; 9.2uM; PC3; HT_HG-U133A

MYL4 SORBS1 ARHGAP35 FYB1 MEF2D GABRA2

3.39e-051967164472_DN
DrugBenfluorex hydrochloride [23642-66-2]; Down 200; 10.4uM; PC3; HT_HG-U133A

PHLDB1 MYL4 GLRB SORBS1 FYB1 UTRN

3.49e-051977166727_DN
DrugClonidine hydrochloride [4205-91-8]; Up 200; 15uM; MCF7; HT_HG-U133A

MYL4 KALRN PCLO TRPV4 RPH3A CIC

3.49e-051977166814_UP
DiseaseNeoplasm of uncertain or unknown behavior of ovary

CDK12 PIK3R1 MAP2K1

4.47e-0529703C0496920
DiseaseOvarian Carcinoma

CDK12 PIK3R1 MAP2K1

4.96e-0530703C0029925
Diseaseattention deficit hyperactivity disorder, substance abuse, antisocial behaviour measurement

NOLC1 ARID1B CPXM2 RBM19 CD40 THSD7B UTRN PHF21A GABRA2

1.13e-04801709EFO_0003888, EFO_0007052, MONDO_0002491
DiseaseCornelia De Lange Syndrome

BRD4 KMT2A

1.54e-048702C0270972
DiseaseMalignant neoplasm of breast

MICALL1 ARID1B KALRN SCARF2 ANKEF1 CD40 SORBS1 DMD CIC TP53BP2

2.14e-0410747010C0006142
Diseasered blood cell density measurement

ARID1B TAF3 KALRN CDK12 PIK3R1 BRD4 SORBS1 FYB1 AP3D1

2.29e-04880709EFO_0007978
Diseasepancreatic adenocarcinoma (is_marker_for)

ADGRB1 MAP2K1

2.47e-0410702DOID:4074 (is_marker_for)
DiseaseCoffin-Siris syndrome

ARID1B SMARCA1

4.25e-0413702C0265338
Diseaserisk-taking behaviour

ARID1B IQCH RBM19 CD40 ADGRB1 THSD7B PHF21A GABRA2

4.46e-04764708EFO_0008579
DiseaseSchwartz-Jampel Syndrome, Type 1

GLB1 TRPV4

6.52e-0416702C4551479
Diseasecentral nervous system disease (implicated_via_orthology)

SMARCA5 SMARCA1

6.52e-0416702DOID:331 (implicated_via_orthology)
DiseaseSpondyloepiphyseal Dysplasia

GLB1 TRPV4

6.52e-0416702C0038015
DiseaseBlood Platelet Disorders

FYB1 AP3D1

6.52e-0416702C0005818
DiseaseSchwartz-Jampel Syndrome

GLB1 TRPV4

6.52e-0416702C0036391
DiseaseMelnick-Needles Syndrome

GLB1 TRPV4

6.52e-0416702C0025237
DiseaseSpondyloepiphyseal Dysplasia Tarda, X-Linked

GLB1 TRPV4

6.52e-0416702C3541456
Diseaseankle brachial index

ARID1B DMD

6.52e-0416702EFO_0003912
DiseaseIntellectual Disability

BRD4 CHAMP1 CIC PHF21A RAI1 GABRA2

6.76e-04447706C3714756
Diseasenon-Hodgkin lymphoma (is_implicated_in)

CD40 KMT2A

7.37e-0417702DOID:0060060 (is_implicated_in)
DiseaseVan Buchem disease

GLB1 TRPV4

7.37e-0417702C0432272
Diseaseischemia (implicated_via_orthology)

ARID1B ADNP

7.37e-0417702DOID:326 (implicated_via_orthology)
Diseasenon-small cell lung carcinoma

PHLDB1 PHACTR2 THSD7B

7.64e-0475703EFO_0003060
DiseaseDyschondroplasias

GLB1 TRPV4

9.24e-0419702C0013366
DiseaseOsteochondrodysplasias

GLB1 TRPV4

9.24e-0419702C0029422
DiseaseMultiple Epiphyseal Dysplasia

GLB1 TRPV4

1.03e-0320702C0026760
Diseasemuscular dystrophy (implicated_via_orthology)

DMD UTRN

1.13e-0321702DOID:9884 (implicated_via_orthology)
DiseaseGlioma

PHLDB1 PIK3R1 CIC

1.18e-0387703C0017638
DiseaseNeurodevelopmental Disorders

ARID1B KMT2A ADNP

1.42e-0393703C1535926
Diseasemyocardial infarction

KALRN PRIM2 FGD6 AHDC1 AP3D1

1.47e-03350705EFO_0000612
DiseaseAdenocarcinoma of large intestine

CDK12 PIK3R1 MAP2K1

1.56e-0396703C1319315
DiseaseAcute monocytic leukemia

KMT2A SLX4

1.74e-0326702C0023465
DiseaseCarcinoma, Ovarian Epithelial

SYNPO2 PHF21A

2.31e-0330702C4721610
Diseaseintellectual disability (is_implicated_in)

ARID1B DMD

2.31e-0330702DOID:1059 (is_implicated_in)

Protein segments in the cluster

PeptideGeneStartEntry
NPPVPPKPQPKVQEK

ADNP

586

Q9H2P0
PEPKAITPPQQPYKK

CDK12

686

Q9NYV4
KEPPPVQKPEKEPEQ

ANTXRL

381

A6NF34
AVKLAFQQKPPPPPK

CLPX

156

O76031
PPGAPDKDKQKQEPK

BRD4

1171

O60885
PDSKPEKQQTPNKRP

ADGRB1

1516

O14514
PKEENKAAEPPPPKI

CCNK

341

O75909
KKEAPAEKQQPPAAP

CEND1

41

Q8N111
PKPAENQKLKGKTPP

ANKEF1

651

Q9NU02
PLKPYPKKPPNQKDV

DEPDC1B

111

Q8WUY9
DTKKQPKLQPPSPAN

ARID1B

1241

Q8NFD5
EQKPSKPAAPQVPPK

CD2AP

376

Q9Y5K6
QVPPKKPTPPTKASN

CD2AP

386

Q9Y5K6
VKHAQEELPPPPPQK

DMD

696

P11532
AKAKFIPKPQPVNPL

AHDC1

1291

Q5TGY3
ANKNVAKVPPPVPTK

TP53BP2

491

Q13625
AKVPPPVPTKPKQIN

TP53BP2

496

Q13625
PVAPKAQKKVPVPEG

AP3D1

606

O14617
PEPPPPGKHSNKKVM

CPXM2

96

Q8N436
MPKKKPTPIQLNPAP

MAP2K1

1

Q02750
PNKPAVPEAPIAKKE

RAI1

976

Q7Z5J4
KHAQKPSQPKQPPKD

RBM19

91

Q9Y4C8
KSPAVKPAAAPKQPV

NOLC1

396

Q14978
PPPSPAEVKFFPKKQ

IQCH

221

Q86VS3
KMPKPKPPPNSEGEQ

CCNC

256

P24863
AKVQKPPPKPGAATE

H1-8

181

Q8IZA3
PVEKRLMPPPPQKNK

GLB1

656

P16278
ATTPEPNKKPENKPA

GABRA2

391

P47869
KQDLSKAPEPKKPPP

PCLO

691

Q9Y6V0
DKNSATPKQKPLPPL

FYB1

336

O15117
PPTPPKNPEEEQKAK

KALRN

1911

O60229
PPAAPKPKREENPQK

PHF21A

351

Q96BD5
QAEPKKKPAPLPPSS

MICALL1

376

Q8N3F8
SQAKNNKKPPPAKPV

GLRB

451

P48167
NKKPPPAKPVIPTAA

GLRB

456

P48167
PEPKKEAAKPAPAPA

MYL4

6

P12829
PPIKKNTKAPGKQAP

PHACTR2

191

O75167
NTKAPGKQAPVPPPK

PHACTR2

196

O75167
ALPPKPPKPTTVANN

PIK3R1

306

P27986
IKKEPIQPETPQPKP

PRIM2

461

P49643
SQKLAPVPSPEPQKP

CHAMP1

196

Q96JM3
TKKPKEPQPEQPQPS

DDX24

841

Q9GZR7
PIKPVTRNKAPQEPP

KMT2A

1131

Q03164
PAVSPESPQKKPPFQ

C3orf86

36

P0DN24
NSLNKVIPAKSPPPP

MEF2D

241

Q14814
MSKPPPKPVKPGQVK

OSTF1

1

Q92882
PEAKPAPSQNRPKTP

TAF3

781

Q5VWG9
QQPPPGEKKPKPEKR

VARS1

256

P26640
QAITKKSKQELPPPP

UTRN

661

P46939
PIKKTKPQQPVSEPA

RPH3A

171

Q9Y2J0
EPKIPKAPRPPKQPN

SMARCA1

771

P28370
RAVKKPAPAPPKPGN

ARHGAP17

631

Q68EM7
KEKDPQPQQLPPMDP

PRAM1

546

Q96QH2
SKLNNKVPPPVKPKP

ARHGAP35

1031

Q9NRY4
EAPQPAVPAPGKKKA

SPAG17

391

Q6Q759
KKNLPPKVPITPMPQ

SLX4

1551

Q8IY92
APKAQRPSPKAPQKV

CIC

1166

Q96RK0
AKQKTPPPVAPKPAV

SYNPO2

751

Q9UMS6
DPEKPPPLPEKKNKH

RAPGEF1

536

Q13905
KPAPPQKAKRSVPPA

SCARF2

801

Q96GP6
LSPPAQKNDPKKAPV

ARHGAP25

361

P42331
PPAEKAQPKKLTPVQ

SORBS1

851

Q9BX66
PVAPKPKFVVANNKP

FGD6

11

Q6ZV73
PKFVVANNKPAPPPI

FGD6

16

Q6ZV73
QNKEQVPPPAVEPKK

TMEM214

71

Q6NUQ4
VPPPAVEPKKPGNKK

TMEM214

76

Q6NUQ4
SPKFQPPVPAPRNKI

PHLDB1

381

Q86UU1
PTKPKPNSQNKPRPP

ZNF469

3831

Q96JG9
NKQLKPKQPPKPPQI

ZFR

316

Q96KR1
LQQKPPDDPVVKPKD

TASOR2

706

Q5VWN6
PKKPKTSEDVPQINP

ZNF280C

186

Q8ND82
KKKRPPQPPEESQPP

PLK2

31

Q9NYY3
KKPKPHQSTPPQQKP

THSD7B

1581

Q9C0I4
EPKAPKAPRPPKQPN

SMARCA5

756

O60264
APLPGSKAKPKPPKQ

TBC1D10A

416

Q9BXI6
KIIEKQPQSPKAPAP

TRPV4

126

Q9HBA0
KPTNKAPHPKQEPQE

CD40

221

P25942
PQNSKKQSPPKKPAP

NDUFV3

46

P56181