Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyBiologicalProcessregulation of SA node cell action potential

ANK2 RYR2

3.90e-053752GO:0098907
GeneOntologyBiologicalProcessregulation of atrial cardiac muscle cell action potential

ANK2 RYR2

7.79e-054752GO:0098910
GeneOntologyBiologicalProcessaxon guidance

PRTG NELL2 LRP1 LRP2 LAMB1 LAMB3 PTCH1

7.95e-05285757GO:0007411
GeneOntologyBiologicalProcessneuron projection guidance

PRTG NELL2 LRP1 LRP2 LAMB1 LAMB3 PTCH1

8.12e-05286757GO:0097485
GeneOntologyBiologicalProcesspositive regulation of lysosomal protein catabolic process

LRP1 LRP2

1.30e-045752GO:1905167
GeneOntologyBiologicalProcesschemoattraction of axon

LRP1 LRP2

1.30e-045752GO:0061642
GeneOntologyBiologicalProcessregulation of AV node cell action potential

ANK2 RYR2

1.30e-045752GO:0098904
GeneOntologyCellularComponentperinuclear region of cytoplasm

NCOR1 UBQLN1 CHERP ANK2 GBP5 SEPTIN14 UBQLN4 LRP1 PPP1R13B LAMB1 PTCH1 DOCK6 SEC23B FBXW7

4.28e-069347414GO:0048471
MousePhenoincreased chromosomal stability

ZSCAN5DP ZSCAN5A ZSCAN5C

1.81e-066643MP:0010095
DomainARM-type_fold

RANBP17 UBQLN1 AP2B1 DOCK8 RTTN HEATR9 ASPM MIF4GD

4.73e-05339728IPR016024
DomainSCAN_BOX

ZSCAN5DP ZSCAN5A ZSCAN5C ZSCAN25

7.36e-0558724PS50804
DomainSCAN

ZSCAN5DP ZSCAN5A ZSCAN5C ZSCAN25

7.36e-0558724PF02023
DomainSCAN_dom

ZSCAN5DP ZSCAN5A ZSCAN5C ZSCAN25

7.36e-0558724IPR003309
DomainRetrov_capsid_C

ZSCAN5DP ZSCAN5A ZSCAN5C ZSCAN25

7.87e-0559724IPR008916
DomainARM-like

RANBP17 AP2B1 DOCK8 RTTN HEATR9 ASPM ARMH4

8.07e-05270727IPR011989
DomainDUF3398

DOCK8 DOCK6

2.18e-046722PF11878
DomainUbiquilin

UBQLN1 UBQLN4

2.18e-046722IPR015496
DomainDOCK_C/D_N

DOCK8 DOCK6

2.18e-046722IPR021816
DomainEGF_1

NELL2 LRP1 LRP2 LAMB1 LAMB3 ADAM28

4.49e-04255726PS00022
DomainEGF-like_CS

NELL2 LRP1 LRP2 LAMB1 LAMB3 ADAM28

5.08e-04261726IPR013032
DomainEGF_2

NELL2 LRP1 LRP2 LAMB1 LAMB3 ADAM28

5.50e-04265726PS01186
DomainSTI1

UBQLN1 UBQLN4

6.46e-0410722SM00727
DomainSTI1_HS-bd

UBQLN1 UBQLN4

6.46e-0410722IPR006636
DomainDOCK_C

DOCK8 DOCK6

7.88e-0411722IPR010703
DomainDHR-1_domain

DOCK8 DOCK6

7.88e-0411722IPR027007
DomainDHR_2

DOCK8 DOCK6

7.88e-0411722PS51651
DomainDHR_1

DOCK8 DOCK6

7.88e-0411722PS51650
DomainDOCK-C2

DOCK8 DOCK6

7.88e-0411722PF14429
DomainDHR-2

DOCK8 DOCK6

7.88e-0411722IPR027357
DomainDHR-2

DOCK8 DOCK6

7.88e-0411722PF06920
DomainDOCK

DOCK8 DOCK6

7.88e-0411722IPR026791
DomainLdl_recept_b

LRP1 LRP2

1.29e-0314722PF00058
DomainLDLRB

LRP1 LRP2

1.29e-0314722PS51120
DomainSCAN

ZSCAN5A ZSCAN5C ZSCAN25

1.32e-0356723SM00431
DomainPLipase_C_Pinositol-sp_Y

PLCL1 PLCG1

1.49e-0315722IPR001711
DomainEF-hand_like

PLCL1 PLCG1

1.49e-0315722PF09279
DomainPIPLC_Y_DOMAIN

PLCL1 PLCG1

1.49e-0315722PS50008
DomainPI-PLC_fam

PLCL1 PLCG1

1.49e-0315722IPR001192
DomainPLC_EF-hand-like

PLCL1 PLCG1

1.49e-0315722IPR015359
DomainPI-PLC-Y

PLCL1 PLCG1

1.49e-0315722PF00387
DomainPLCYc

PLCL1 PLCG1

1.49e-0315722SM00149
DomainLY

LRP1 LRP2

1.49e-0315722SM00135
DomainLDLR_classB_rpt

LRP1 LRP2

1.49e-0315722IPR000033
Domain-

RANBP17 AP2B1 RTTN HEATR9 ASPM

1.66e-032227251.25.10.10
DomainLaminin_N

LAMB1 LAMB3

1.70e-0316722IPR008211
DomainLAMININ_NTER

LAMB1 LAMB3

1.70e-0316722PS51117
DomainLaminin_N

LAMB1 LAMB3

1.70e-0316722PF00055
DomainLamNT

LAMB1 LAMB3

1.70e-0316722SM00136
DomainEGF

NELL2 LRP1 LRP2 LAMB1 ADAM28

2.13e-03235725SM00181
DomainPI-PLC-X

PLCL1 PLCG1

2.15e-0318722PF00388
DomainPLCXc

PLCL1 PLCG1

2.15e-0318722SM00148
DomainPIPLC_X_DOMAIN

PLCL1 PLCG1

2.40e-0319722PS50007
DomainPLipase_C_PInositol-sp_X_dom

PLCL1 PLCG1

2.40e-0319722IPR000909
Domain6-PGluconate_DH_C-like

UBQLN1 UBQLN4

2.40e-0319722IPR008927
DomainEGF-like_dom

NELL2 LRP1 LRP2 LAMB1 ADAM28

2.74e-03249725IPR000742
DomainGrowth_fac_rcpt_

NELL2 LRP1 LRP2 LAMB1

3.10e-03156724IPR009030
DomainC2H2_Znf_fam

ZSCAN5A REST

3.83e-0324722IPR027775
Domain-

PLCL1 PLCG1

4.15e-03257223.20.20.190
DomainPLC-like_Pdiesterase_TIM-brl

PLCL1 PLCG1

4.15e-0325722IPR017946
DomainEGF_CA

NELL2 LRP1 LRP2

4.47e-0386723PF07645
DomaincEGF

LRP1 LRP2

4.49e-0326722IPR026823
DomaincEGF

LRP1 LRP2

4.49e-0326722PF12662
DomainEGF_LAM_2

LAMB1 LAMB3

5.95e-0330722PS50027
DomainEGF_LAM_1

LAMB1 LAMB3

5.95e-0330722PS01248
DomainUBA

UBQLN1 UBQLN4

5.95e-0330722SM00165
DomainEGF_Ca-bd_CS

NELL2 LRP1 LRP2

6.25e-0397723IPR018097
DomainEGF_CA

NELL2 LRP1 LRP2

6.61e-0399723PS01187
DomainASX_HYDROXYL

NELL2 LRP1 LRP2

6.80e-03100723PS00010
Pubmed

Zscan5b Deficiency Impairs DNA Damage Response and Causes Chromosomal Aberrations during Mitosis.

ZSCAN5DP ZSCAN5A ZSCAN5C

3.85e-08475331155506
Pubmed

ZSCAN5B and primate-specific paralogs bind RNA polymerase III genes and extra-TFIIIC (ETC) sites to modulate mitotic progression.

ZSCAN5DP ZSCAN5A ZSCAN5C

3.85e-08475327732952
Pubmed

Endocytic Protein Defects in the Neural Crest Cell Lineage and Its Pathway Are Associated with Congenital Heart Defects.

LRP1 LRP2

4.59e-06275234445520
Pubmed

Functional proteomics mapping of a human signaling pathway.

NCOR1 UBQLN1 DOCK8 UBQLN4 LRP1 PPP1R13B VCL RYR2 KNL1

5.15e-0659175915231748
Pubmed

Identification of motif-based interactions between SARS-CoV-2 protein domains and human peptide ligands pinpoint antiviral targets.

NCOR1 BBX ETV5 DNAH7 AKAP12 SLC45A4

1.16e-0523375637704626
Pubmed

ASPM stabilizes the NOTCH intracellular domain 1 and promotes oncogenesis by blocking FBXW7 binding in hepatocellular carcinoma cells.

ASPM FBXW7

1.37e-05375238279565
Pubmed

Human gastric cancer progression and stabilization of ATG2B through RNF5 binding facilitated by autophagy-associated CircDHX8.

ATG2B DHX8

1.37e-05375238866787
Pubmed

Postmortem genetic analysis of sudden unexplained death syndrome under 50 years of age: A next-generation sequencing study.

ANK2 RYR2

1.37e-05375227005929
Pubmed

Intestinal NCoR1, a regulator of epithelial cell maturation, controls neonatal hyperbilirubinemia.

NCOR1 CYP3A43 LRP2

2.71e-052775328167773
Pubmed

Disabled-2 is essential for endodermal cell positioning and structure formation during mouse embryogenesis.

LRP1 LRP2

2.75e-05475212413896
Pubmed

Functions of sorting nexin 17 domains and recognition motif for P-selectin trafficking.

LRP1 PTCH1

2.75e-05475215769472
Pubmed

Herp enhances ER-associated protein degradation by recruiting ubiquilins.

UBQLN1 UBQLN4

2.75e-05475218307982
Pubmed

Identification of the low density lipoprotein receptor-related protein (LRP) as an endocytic receptor for thrombospondin-1.

LRP1 LRP2

2.75e-0547527775583
Pubmed

Role of apolipoprotein E receptors in regulating the differential in vivo neurotrophic effects of apolipoprotein E.

LRP1 LRP2

2.75e-05475211421580
Pubmed

Genetic link between renal birth defects and congenital heart disease.

FREM2 AP2B1 LRP2

3.04e-052875327002738
Pubmed

Endocytic recycling protein EHD1 regulates primary cilia morphogenesis and SHH signaling during neural tube development.

MYOF AP2B1 PTCH1

3.04e-052875326884322
Pubmed

Basement membrane assembly of the integrin α8β1 ligand nephronectin requires Fraser syndrome-associated proteins.

FREM2 LAMB1 LAMB3

3.38e-052975322613833
Pubmed

Proximity-dependent biotin identification (BioID) reveals a dynamic LSD1-CoREST interactome during embryonic stem cell differentiation.

NCOR1 GAPVD1 UBQLN4 ATG2B LRP1 LRP2 KNL1

3.39e-0541875734709266
Pubmed

NLRP14 deficiency causes female infertility with oocyte maturation defects and early embryonic arrest by impairing cytoplasmic UHRF1 abundance.

ZSCAN5DP ZSCAN5A ZSCAN5C

4.57e-053275338060382
Pubmed

ApoER2 is endocytosed by a clathrin-mediated process involving the adaptor protein Dab2 independent of its Rafts' association.

LRP1 LRP2

4.57e-05575216101684
Pubmed

Interaction of the apolipoprotein E receptors low density lipoprotein receptor-related protein and sorLA/LR11.

LRP1 LRP2

4.57e-05575219047013
Pubmed

NELL2-mediated lumicrine signaling through OVCH2 is required for male fertility.

NELL2 ADAM28

4.57e-05575232499443
Pubmed

Interaction of coagulation factor VIII with members of the low-density lipoprotein receptor family follows common mechanism and involves consensus residues within the A2 binding site 484-509.

LRP1 LRP2

4.57e-05575218685438
Pubmed

A protein-protein interaction network for human inherited ataxias and disorders of Purkinje cell degeneration.

NCOR1 NELL2 UBQLN1 UBQLN4 MIF4GD LRP2 LAMB1 KAT6B

5.02e-0560875816713569
Pubmed

Combinatorial CRISPR screen identifies fitness effects of gene paralogues.

RANBP17 EPC1 ASPM SEC23B FBXW7

5.28e-0518675533637726
Pubmed

Resolution of cell fate decisions revealed by single-cell gene expression analysis from zygote to blastocyst.

NCOR1 BBX ZSCAN5DP ZSCAN5A ZSCAN5C ETV5 PLCG1 REST KAT6B

6.02e-0580875920412781
Pubmed

Global genetic analysis in mice unveils central role for cilia in congenital heart disease.

FREM2 AP2B1 LRP1 LRP2

6.69e-0510075425807483
Pubmed

Expression and localization of laminin-5 subunits in the mouse incisor.

LAMB1 LAMB3

6.84e-0567529506922
Pubmed

RTL8 promotes nuclear localization of UBQLN2 to subnuclear compartments associated with protein quality control.

UBQLN1 UBQLN4

6.84e-05675235247097
Pubmed

Interaction of cytosolic adaptor proteins with neuronal apolipoprotein E receptors and the amyloid precursor protein.

LRP1 LRP2

6.84e-0567529837937
Pubmed

Expansion of the renal capsular stroma, ureteric bud branching defects and cryptorchidism in mice with Wilms tumor 1 gene deletion in the stromal compartment of the developing kidney.

ETV5 PTCH1 AKAP12

7.70e-053875332715478
Pubmed

Blood-Brain Barrier: From Physiology to Disease and Back.

LRP1 LRP2 SLC38A3 VCL

8.08e-0510575430280653
Pubmed

Assembly of the WHIP-TRIM14-PPP6C Mitochondrial Complex Promotes RIG-I-Mediated Antiviral Signaling.

IVNS1ABP NCOR1 MAEA PLCG1 AKAP12 VCL

8.37e-0533275629053956
Pubmed

Chr21 protein-protein interactions: enrichment in proteins involved in intellectual disability, autism, and late-onset Alzheimer's disease.

NELL2 UBQLN1 ANK2 AP2B1 UBQLN4 ADGRB3 LRP1 LRP2 LAMB1 MAGI3 PLCG1

9.40e-051285751135914814
Pubmed

Megalin mediates the influence of sonic hedgehog on oligodendrocyte precursor cell migration and proliferation during development.

LRP2 PTCH1

9.57e-05775222354480
Pubmed

Laminins promote the locomotion of skeletal myoblasts via the alpha 7 integrin receptor.

LAMB1 LAMB3

9.57e-0577529004048
Pubmed

Defects and rescue of the minor salivary glands in Eda pathway mutants.

ETV5 PTCH1

9.57e-05775220969842
Pubmed

The PX-domain protein SNX17 interacts with members of the LDL receptor family and modulates endocytosis of the LDL receptor.

LRP1 LRP2

9.57e-05775212169628
Pubmed

Structure of hRpn10 Bound to UBQLN2 UBL Illustrates Basis for Complementarity between Shuttle Factors and Substrates at the Proteasome.

UBQLN1 UBQLN4

9.57e-05775230664872
Pubmed

ING tumor suppressor proteins are critical regulators of chromatin acetylation required for genome expression and perpetuation.

YEATS4 EPC1 KAT6B

1.04e-044275316387653
Pubmed

Expression and localization of laminin-5 subunits during mouse tooth development.

LAMB1 LAMB3

1.27e-0487529489770
Pubmed

Ubiquilin4 is an adaptor protein that recruits Ubiquilin1 to the autophagy machinery.

UBQLN1 UBQLN4

1.27e-04875223459205
Pubmed

Mouse kalinin B1 (laminin beta 3 chain): cloning and tissue distribution.

LAMB1 LAMB3

1.27e-0487527898049
Pubmed

Spatial and temporal control of laminin-332 and -511 expressions during hair morphogenesis.

LAMB1 LAMB3

1.27e-04875223529140
Pubmed

Transcriptome analysis of mouse stem cells and early embryos.

MYOF IQCA1L ZSCAN5DP ZSCAN5A ZSCAN5C ASPM

1.36e-0436375614691545
Pubmed

Systematic bromodomain protein screens identify homologous recombination and R-loop suppression pathways involved in genome integrity.

NELL2 YEATS4 RTL9 EPC1 ASPM LRP1 LRP2 LAMB1 KAT6B KNL1

1.39e-041116751031753913
Pubmed

LDL receptor-related protein as a component of the midkine receptor.

LRP1 LRP2

1.64e-04975210772929
Pubmed

N-Terminal Acetyltransferase Naa40p Whereabouts Put into N-Terminal Proteoform Perspective.

GAPVD1 CHERP ANK2 AP2B1 ATG2B PLCG1 AKAP12 VCL KNL1

1.80e-0493475933916271
Pubmed

Establishment and Dysfunction of the Blood-Brain Barrier.

LRP1 LRP2 SLC38A3

1.97e-045275326590417
Pubmed

Distribution of the ten known laminin chains in the pathways and targets of developing sensory axons.

LAMB1 LAMB3

2.04e-04107529034910
Pubmed

A dosage-dependent role for Spry2 in growth and patterning during palate development.

ETV5 PTCH1

2.04e-041075217693063
Pubmed

A forward genetic screen in mice identifies mutants with abnormal cortical patterning.

LRP2 DRC3

2.49e-041175223968836
Pubmed

The highly conserved and multifunctional NuA4 HAT complex.

YEATS4 EPC1

2.49e-041175215196461
Pubmed

Fuz mutant mice reveal shared mechanisms between ciliopathies and FGF-related syndromes.

ETV5 PTCH1

2.49e-041175223806618
Pubmed

The histone H3K4 demethylase SMCX links REST target genes to X-linked mental retardation.

NCOR1 REST

2.49e-041175217468742
Pubmed

LRP2 mediates folate uptake in the developing neural tube.

LRP1 LRP2

2.49e-041175224639464
Pubmed

Regional differences in the expression of laminin isoforms during mouse neural tube development.

LAMB1 LAMB3

2.49e-041175221524702
Pubmed

Mutations in LAMB1 cause cobblestone brain malformation without muscular or ocular abnormalities.

LAMB1 LAMB3

2.49e-041175223472759
Pubmed

ZAR1 and ZAR2 are required for oocyte meiotic maturation by regulating the maternal transcriptome and mRNA translational activation.

ZSCAN5DP ZSCAN5A ZSCAN5C

2.73e-045875331598710
Pubmed

NRSF regulates the fetal cardiac gene program and maintains normal cardiac structure and function.

REST RYR2

2.99e-041275214633990
Pubmed

Control of chromosome stability by the beta-TrCP-REST-Mad2 axis.

REST FBXW7

2.99e-041275218354482
Pubmed

Muscle progenitor cells failing to respond to positional cues adopt non-myogenic fates in myf-5 null mice.

LAMB1 LAMB3

2.99e-04127528918877
Pubmed

Nubp2 is required for cranial neural crest survival in the mouse.

ETV5 PTCH1

2.99e-041275231733190
Pubmed

Distribution and function of laminins in the neuromuscular system of developing, adult, and mutant mice.

LAMB1 LAMB3

2.99e-04127529396756
Pubmed

Excess NF-κB induces ectopic odontogenesis in embryonic incisor epithelium.

ETV5 PTCH1

3.52e-041375225376721
Pubmed

Sequence diversity and haplotype structure at the human CYP3A cluster.

CYP3A43 ZSCAN25

3.52e-041375216314882
Pubmed

UBQLN2 Mediates Autophagy-Independent Protein Aggregate Clearance by the Proteasome.

UBQLN1 UBQLN4

3.52e-041375227477512
Pubmed

Preaxial polydactyly: interactions among ETV, TWIST1 and HAND2 control anterior-posterior patterning of the limb.

ETV5 PTCH1

4.11e-041475220826535
Pubmed

Conditional deletion of NRSF in forebrain neurons accelerates epileptogenesis in the kindling model.

PLCG1 REST

4.11e-041475221339379
Pubmed

Stage-specific association of apolipoprotein A-I and E in developing mouse retina.

LRP1 LRP2

4.11e-041475217389516
Pubmed

Normal development and fertility of knockout mice lacking the tumor suppressor gene LRP1b suggest functional compensation by LRP1.

LRP1 LRP2

4.11e-041475215082773
Pubmed

Identification of an evolutionarily conserved superfamily of DOCK180-related proteins with guanine nucleotide exchange activity.

DOCK8 DOCK6

4.11e-041475212432077
Pubmed

Basement membrane composition in the early mouse embryo day 7.

LAMB1 LAMB3

4.73e-041575215895400
Pubmed

Mapping of quantitative trait loci determining NK cell-mediated resistance to MHC class I-deficient bone marrow grafts in perforin-deficient mice.

GBP5 PLCG1

4.73e-041575217114464
Pubmed

Localization of basement membrane-associated protein isoforms during development of the ocular surface of mouse eye.

LAMB1 LAMB3

4.73e-04157529264260
Pubmed

LRP2 is an auxiliary SHH receptor required to condition the forebrain ventral midline for inductive signals.

LRP2 PTCH1

4.73e-041575222340494
Pubmed

The human cytoplasmic dynein interactome reveals novel activators of motility.

NCOR1 GAPVD1 LRP2 PPP1R13B MAGI3 FHIP2A DNAH7 VCL

5.02e-0485375828718761
Pubmed

An organelle-specific protein landscape identifies novel diseases and molecular mechanisms.

IVNS1ABP GAPVD1 YEATS4 BBX AP2B1 MAEA RTL9 ATG2B AKAP12 VCL

5.31e-041321751027173435
Pubmed

Hand1 phosphoregulation within the distal arch neural crest is essential for craniofacial morphogenesis.

ETV5 PTCH1

5.40e-041675225053435
Pubmed

Laminin alpha5 is necessary for submandibular gland epithelial morphogenesis and influences FGFR expression through beta1 integrin signaling.

LAMB1 LAMB3

5.40e-041675217601529
Pubmed

Late gestational lung hypoplasia in a mouse model of the Smith-Lemli-Opitz syndrome.

LRP2 PTCH1

5.40e-041675215005800
Pubmed

Sonic hedgehog-dependent activation of Gli2 is essential for embryonic hair follicle development.

LAMB3 PTCH1

5.40e-041675212533516
Pubmed

Mammalian Tead proteins regulate cell proliferation and contact inhibition as transcriptional mediators of Hippo signaling.

ETV5 VCL

5.40e-041675219004856
Pubmed

Primary Autosomal Recessive Microcephalies and Seckel Syndrome Spectrum Disorders – RETIRED CHAPTER, FOR HISTORICAL REFERENCE ONLY

ASPM KNL1

5.40e-041675220301772
Pubmed

The Genetic Basis of Baculum Size and Shape Variation in Mice.

ASPM PLCG1

5.40e-041675226935419
Pubmed

A proteome-scale map of the SARS-CoV-2-human contactome.

UBQLN1 LCN15 MIF4GD DHX8

5.46e-0417375436217029
Pubmed

LRP2/megalin is required for patterning of the ventral telencephalon.

LRP2 PTCH1

6.11e-041775215623804
Pubmed

TGF-beta-1 up-regulates extra-cellular matrix production in mouse hepatoblasts.

LAMB1 LAMB3

6.87e-041875223041440
Pubmed

Gata6-Dependent GLI3 Repressor Function is Essential in Anterior Limb Progenitor Cells for Proper Limb Development.

ETV5 PTCH1

6.87e-041875227352137
Pubmed

Tissue-specific roles of FGF signaling in external genitalia development.

ETV5 PTCH1

6.87e-041875225820239
Pubmed

A direct functional link between the multi-PDZ domain protein GRIP1 and the Fraser syndrome protein Fras1.

FREM2 LAMB1

6.87e-041875214730302
Pubmed

Amplification of extracellular matrix and oncogenes in tat-transfected human salivary gland cell lines with expression of laminin, fibronectin, collagens I, III, IV, c-myc and p53.

LAMB1 LAMB3

6.87e-041875211311202
Pubmed

Interactions of the low density lipoprotein receptor gene family with cytosolic adaptor and scaffold proteins suggest diverse biological functions in cellular communication and signal transduction.

LRP1 LRP2

6.87e-041875210827173
Pubmed

Estrogen-regulated feedback loop limits the efficacy of estrogen receptor-targeted breast cancer therapy.

IVNS1ABP UBQLN1 ETV5 LAMB3 FHIP2A C2orf78 ADAM28

7.00e-0468675729987050
Pubmed

Specific 3-O-sulfated heparan sulfate domains regulate salivary gland basement membrane metabolism and epithelial differentiation.

ETV5 LAMB1 LAMB3

7.28e-048175339217171
Pubmed

The mammalian YL1 protein is a shared subunit of the TRRAP/TIP60 histone acetyltransferase and SRCAP complexes.

YEATS4 EPC1

7.66e-041975215647280
Pubmed

SP8 regulates signaling centers during craniofacial development.

ETV5 PTCH1

7.66e-041975223872235
Pubmed

The glomuvenous malformation protein Glomulin binds Rbx1 and regulates cullin RING ligase-mediated turnover of Fbw7.

VCL FBXW7

7.66e-041975222405651
Pubmed

Tagging genes with cassette-exchange sites.

RANBP17 NCOR1 CHERP REST KAT6B

8.00e-0433575515741177
Pubmed

An improved method for the synthesis of cellulose membrane-bound peptides with free C termini is useful for PDZ domain binding studies.

ADGRB3 LAMB1 NMU

8.10e-048475315123239
InteractionSLC45A4 interactions

UBQLN1 UBQLN4 SLC45A4

7.37e-0611733int:SLC45A4
Cytoband19q13.43

ZSCAN5DP ZSCAN5A ZSCAN5C

4.02e-048775319q13.43
Cytoband10q24

MYOF PDE6C

1.51e-033575210q24
Cytoband10q22.2

KAT6B VCL

2.07e-034175210q22.2
GeneFamilyUbiquilin family

UBQLN1 UBQLN4

6.87e-055482783
GeneFamilyLaminin subunits

LAMB1 LAMB3

4.48e-0412482626
GeneFamilyLow density lipoprotein receptors

LRP1 LRP2

5.28e-0413482634
GeneFamilyPhospholipases|C2 domain containing phospholipases

PLCL1 PLCG1

1.15e-0319482832
GeneFamilyArmadillo repeat containing|Protein phosphatase 1 regulatory subunits

NCOR1 PPP1R13B PLCL1 KNL1

1.34e-03181484694
CoexpressionAtlasMESO-30 amniotic fluid MSC_vs_MESO-30 blastocyst-Confounder_removed-fold2.0_adjp0.05

PRTG NELL2 BBX ANK2 RTTN LRP2 ETV5 MAGI3 RENBP PLCG1 ZSCAN25 PTCH1 KAT6B DOCK6 AKAP12 FBXW7

2.65e-0612457116PCBC_ratio_MESO-30 amniotic fluid MSC_vs_MESO-30 blastocyst_cfr-2X-p05
CoexpressionAtlasdev gonad_e12.5_M_InterstitLeydig_MafB_k-means-cluster#2_top-relative-expression-ranked_500

MYOF ASPM LRP1 LBH PTCH1 ARMH4

1.90e-05165716gudmap_dev gonad_e12.5_M_InterstitLeydig_MafB_k2_500
CoexpressionAtlasdev gonad_e12.5_M_InterstitTestis_Sma_top-relative-expression-ranked_1000

MYOF ASPM LRP1 LBH ETV5 PPP1R13B LAMB1 REST PTCH1 KNL1 ARMH4

6.09e-057937111gudmap_dev gonad_e12.5_M_InterstitTestis_Sma_1000
ToppCellLPS_only-Stromal_mesenchymal-Matrix_Fibroblast-MatrixFB|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

MYOF ANK2 ADGRB3 LRP1 LAMB1 PTCH1 RYR2

3.22e-081897572a22b9fae70afb3dab8476f9c00e48a4df756410
ToppCellLPS_anti-TNF-Mesenchymal_fibroblastic-Fibroblasts-Activated_MatrixFB|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type

MYOF ANK2 LRP1 LBH LAMB1 AKAP12 RYR2

4.28e-08197757fdb92985f7df0c280b87d3e43c2394e70786a2c7
ToppCellLPS_IL1RA-Mesenchymal_fibroblastic-Fibroblasts-MatrixFB|LPS_IL1RA / Treatment groups by lineage, cell group, cell type

MYOF ANK2 LRP1 LBH LAMB1 PTCH1 RYR2

4.58e-08199757a7dd94b172c973a131a6792f8ccd9bfe44d984ac
ToppCellLPS_IL1RA_TNF-Mesenchymal_fibroblastic-Fibroblasts-MatrixFB|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type

MYOF ANK2 LRP1 LBH LAMB1 PTCH1 AKAP12

4.58e-0819975730d3e8c0681ec11f86dd38c5f48d21187a1b4f90
ToppCellLPS_anti-TNF-Mesenchymal_fibroblastic-Fibroblasts-MatrixFB|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type

MYOF ANK2 LRP1 LBH LAMB1 PTCH1 AKAP12

4.74e-082007579b0916d8d07ac2bf1739f7be5296bf77ffee6094
ToppCellParenchymal-NucSeq-Stromal|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

ANK2 ADGRB3 LRP1 LBH LAMB1 AKAP12 RYR2

4.74e-08200757cf433f9b43d7db07acaf70e060f8f77c974e72f3
ToppCellLPS_only-Mesenchymal_fibroblastic-Fibroblasts-MatrixFB|LPS_only / Treatment groups by lineage, cell group, cell type

MYOF ANK2 LRP1 LAMB1 PTCH1 AKAP12 RYR2

4.74e-08200757a7ef7022b8efcaedb7319b0b43d8c4e99d788fe2
ToppCellParenchymal-NucSeq-Stromal-Fibroblastic|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

ANK2 ADGRB3 LRP1 LBH LAMB1 AKAP12 RYR2

4.74e-08200757311fab076f2ceb258e3970eb21e39344b894042a
ToppCellfacs-Brain_Non-Myeloid-Cerebellum-3m-Macroglial-oligodendrocyte_precursor_cell|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NELL2 LRP1 LBH ETV5 GRIK3 ARMH4

7.79e-07188756a244fcd092d5bd544e503366b1439b0fbc1ee00e
ToppCellfacs-Brain_Non-Myeloid-Cerebellum-3m-Macroglial-Oligodendrocyte_progenitor_cell|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NELL2 LRP1 LBH ETV5 GRIK3 ARMH4

7.79e-07188756c8530c9ff98666c64a94683261af4288cb790a7e
ToppCellRV-04._Ventricular_Cardiomyocyte_I|RV / Chamber and Cluster_Paper

ANK2 PPP1R13B CHST9 PLCL1 VCL RYR2

8.03e-071897569c1debd65c13d63fd4f3158917d621b44b714c26
ToppCellLPS-IL1RA-Stromal_mesenchymal-Matrix_Fibroblast|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

MYOF ANK2 LRP1 LBH LAMB1 RYR2

8.80e-07192756f4fc2b0121f879bab2bee99dfb5ff2c3ca1c0e1b
ToppCellEpithelial-alveolar_epithelial_cell_type_2|World / Lineage, Cell type, age group and donor

FREM2 PRTG LRP2 ETV5 PPP1R13B MAGI3

8.80e-0719275658c3737be7acce39fd2b91d70d6d7b2bbaa4f710
ToppCellFetal_29-31_weeks-Epithelial-alveolar_epithelial_cell_type_1/2_(AT1/AT2-like)-D062|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

RANBP17 FREM2 PPP1R13B MAGI3 PLCL1 NMU

8.80e-0719275629f49f00770c991b5f27e4cb701dd2d2d6cb7178
ToppCellLPS-IL1RA+antiTNF-Stromal_mesenchymal|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

MYOF ANK2 LRP1 LBH LAMB1 RYR2

8.80e-071927563d0cb19f037f604253d7d728689aeaa94251e92b
ToppCellPCW_07-8.5-Epithelial-Epithelial_neuroendo-epi_NE_progenitor_(7)|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

FREM2 ANK2 LRP2 LAMB3 CHST9 DNAH7

8.80e-07192756b99f8236ef4ccdc75c02abea381cae6453205f6f
ToppCellLPS-IL1RA-Stromal_mesenchymal|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

MYOF ANK2 LRP1 LBH LAMB1 RYR2

8.80e-071927564e47a02007f562f29ba5910df64d32a0167d0bd1
ToppCellLPS-antiTNF-Stromal_mesenchymal|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

MYOF ANK2 LRP1 LBH LAMB1 RYR2

9.35e-071947566e13549f697f7478b34fe71f7dd9d63c5d3db22e
ToppCellwk_15-18-Epithelial-Airway_epithelial_progenitor-epi-stalk_late|wk_15-18 / Celltypes from embryonic and fetal-stage human lung

FREM2 NELL2 ETV5 PPP1R13B LAMB3 MAGI3

1.05e-061987561851b7f4198b42c21c934e2fbda39dbd65e2625c
ToppCellControl_saline-Mesenchymal_fibroblastic-Fibroblasts-Activated_MatrixFB|Control_saline / Treatment groups by lineage, cell group, cell type

ANK2 ADGRB3 LBH LAMB1 PTCH1 RYR2

1.05e-061987560c4d2c68a42f8a9e964e2dd28092fe75f5216834
ToppCellLPS_only-Mesenchymal_fibroblastic|LPS_only / Treatment groups by lineage, cell group, cell type

MYOF ANK2 LRP1 LBH LAMB1 AKAP12

1.08e-06199756211c3a08f2d484ab7a3368006767289088f0d957
ToppCellLPS_IL1RA_TNF-Mesenchymal_fibroblastic-Fibroblasts-Activated_MatrixFB|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type

MYOF ANK2 LRP1 LBH LAMB1 AKAP12

1.08e-06199756e1849505b92820a219c5a2c35492bdd55579fb48
ToppCellLPS_only-Mesenchymal_fibroblastic-Fibroblasts|LPS_only / Treatment groups by lineage, cell group, cell type

MYOF ANK2 LRP1 LBH LAMB1 AKAP12

1.08e-061997561a0add79f4e34078b3475eb11c85a4234bda197c
ToppCellLPS_anti-TNF-Mesenchymal_fibroblastic-Fibroblasts|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type

MYOF ANK2 LRP1 LBH LAMB1 AKAP12

1.12e-06200756b79628fd1386aa9a3b0e9fa81def0bc100c3c073
ToppCellLPS_anti-TNF-Mesenchymal_fibroblastic|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type

MYOF ANK2 LRP1 LBH LAMB1 AKAP12

1.12e-0620075650ca6550998e461ef26dd670351060bd940765a8
ToppCellBronchial-NucSeq-Stromal|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

ANK2 ADGRB3 LRP1 LAMB1 AKAP12 RYR2

1.12e-06200756389cc775c8419d90fb77cd794376d2160a7bf44e
ToppCellBronchial-NucSeq-Stromal-Fibroblastic-Fibro_alveolar|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

ADGRB3 LRP1 LBH LAMB1 AKAP12 RYR2

1.12e-06200756e8462395fee0a532d1e7ec7f1795f28c42af6541
ToppCellControl_saline-Mesenchymal_myocytic|Control_saline / Treatment groups by lineage, cell group, cell type

MYOF LRP1 LAMB1 PTCH1 VCL RYR2

1.12e-062007565ed4261157cd51109b314818133ac3a0d34ee5fa
ToppCellLPS_anti-TNF-Mesenchymal_fibroblastic-Fibroblasts-Diff_MatrixFB|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type

MYOF ANK2 LRP1 LBH LAMB1 AKAP12

1.12e-062007563bdba9612cd7c612b76aa9abecc4a6529aabfc1c
ToppCellLPS_IL1RA_TNF-Mesenchymal_fibroblastic-Fibroblasts|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type

MYOF ANK2 LRP1 LBH LAMB1 AKAP12

1.12e-0620075644a68bacdb3d5bf563bd35952176995850933a81
ToppCellBronchial-NucSeq-Stromal-Fibroblastic|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

ANK2 ADGRB3 LRP1 LAMB1 AKAP12 RYR2

1.12e-06200756cae972324d1dfea6efeaf6013f265c7c6bb48db4
ToppCellLPS_IL1RA_TNF-Mesenchymal_fibroblastic|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type

MYOF ANK2 LRP1 LBH LAMB1 AKAP12

1.12e-06200756dc61016c61729f69649cfb21f6264e685ce83dea
ToppCellControl_saline-Mesenchymal_fibroblastic-Fibroblasts-MatrixFB|Control_saline / Treatment groups by lineage, cell group, cell type

ANK2 LRP1 LBH LAMB1 PTCH1 AKAP12

1.12e-06200756bd8cf33502adea320e91ca2af14e1911d88ad374
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell-Cortical_Collecting_Duct_Principal_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

IVNS1ABP FREM2 LRP2 SLC13A5 SLC45A4

5.69e-06151755f4f7156b2c0cfc78fd1841e07c9915d97ced561f
ToppCell356C-Lymphocytic-ILC-ILC-3|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)

HEATR9 ETV5 CHST9 KAT6B ARMH4

8.25e-061637552dbdcbc4c187aad3db837d191cc78662a75dd0b5
ToppCellPBMC-Mild-Lymphocyte-T/NK-CD4+_T-Treg-Treg_6|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

GBP5 LBH PLCL1 PLCG1 FHIP2A

8.76e-06165755dbe231d00843cae917efd1abea6079ace3b45cdf
ToppCellPBMC-Mild-Lymphocyte-T/NK-CD4+_T-Treg-Treg_6|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

GBP5 LBH PLCL1 PLCG1 FHIP2A

8.76e-061657559ccce713d4122054bf4bef4a7126d90cf9141b84
ToppCellTCGA-Ovary-Primary_Tumor-Ovarian_Carcinoma-Serous_Cystadenocarcinoma-5|TCGA-Ovary / Sample_Type by Project: Shred V9

BBX CHERP EPC1 ZSCAN25 SLC45A4

9.02e-0616675532d2eaf8a5d03881bf74d680825af2d5110b082d
ToppCellPND01-Endothelial-Endothelial_blood-vessel-Microvascular_EC-EPC-EPC_G2M|PND01 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

ASPM PPP1R13B RTN4IP1 SLC38A3 KNL1

1.20e-051767558385435074cc5235b7af7424974f609388fc2cff
ToppCellCOVID-19-Epithelial_cells-AT2|COVID-19 / group, cell type (main and fine annotations)

RANBP17 FREM2 PRTG LRP2 MAGI3

1.48e-05184755369b82f793deab672204558ae4e112cfa5aa9ccc
ToppCellChildren_(3_yrs)-Epithelial-alveolar_epithelial_cell_type_2/Club-like_(AT2/Club-like)-D139|Children_(3_yrs) / Lineage, Cell type, age group and donor

FREM2 PRTG PPP1R13B MAGI3 PLCL1

1.48e-05184755102105ae1a5ef6d42a43f6d9b00f12ed0690ddb7
ToppCellControl-Epithelial_alveolar-AT_2-Differentiating_AT2|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

FREM2 NELL2 ETV5 LAMB3 MAGI3

1.52e-051857550d2add28ac1f4fa6de7699be009bf8391badaf4c
ToppCellRV-06._Ventricular_Cardiomyocyte_II|World / Chamber and Cluster_Paper

ANK2 PPP1R13B CHST9 PLCL1 RYR2

1.69e-051897555e80c47f63980904c4c1ff02c201b67b456a0974
ToppCellPND07-28-samps-Mesenchymal-Matrix_fibroblast|PND07-28-samps / Age Group, Lineage, Cell class and subclass

LBH LAMB1 PTCH1 AKAP12 VCL

1.69e-05189755dc5164591dea45b420798b94dda211be03daa70c
ToppCellFetal_29-31_weeks-Epithelial-alveolar_epithelial_cell_type_1/2_(AT1/AT2-like)-D150|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

RANBP17 FREM2 ETV5 PPP1R13B MAGI3

1.73e-051907558aea807a2bcf0b653b4de6202b6ecb0f0683cc2e
ToppCellLV-06._Ventricular_Cardiomyocyte_II|World / Chamber and Cluster_Paper

ANK2 PPP1R13B CHST9 PLCL1 RYR2

1.73e-05190755de5ef606a002f85c2e0e3a36c1f259d0b85a76ff
ToppCellPND07-28-samps-Mesenchymal-Matrix_fibroblast-FB-3|PND07-28-samps / Age Group, Lineage, Cell class and subclass

LBH LAMB1 PTCH1 AKAP12 VCL

1.73e-051907551196b8ea2c44c7c80f5ee589dd517e6a413f2077
ToppCellPCW_07-8.5-Epithelial-Epithelial_alveolar-distal-epi_SOX9^high_Etv5^high_distal_(10)|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

FREM2 LRP2 ETV5 LAMB3 CHST9

1.73e-05190755625c08a0e5227efc46daa512fd579c3938ff76c7
ToppCellLPS-IL1RA-Stromal_mesenchymal-Matrix_Fibroblast-Activated_MatrixFB|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

MYOF ANK2 LRP1 LAMB1 RYR2

1.73e-0519075545df8fee00f8949937863159d7aa042e72748d9b
ToppCellfacs-Brain_Non-Myeloid-Cortex-3m-Macroglial-oligodendrocyte_precursor_cell|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NELL2 LRP1 ETV5 GRIK3 ARMH4

1.73e-051907559b825b2586c7b173ff27fcf2abc5860faf50984a
ToppCellControl-Fibroblasts|Control / group, cell type (main and fine annotations)

ANK2 ADGRB3 LAMB1 AKAP12 RYR2

1.73e-051907553a42a9b98d954685d38a741f44545898d0e3e9ce
ToppCellfacs-Brain_Non-Myeloid-Cortex-3m-Macroglial-Oligodendrocyte_progenitor_cell|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NELL2 LRP1 ETV5 GRIK3 ARMH4

1.73e-05190755d146af1926474328a7c822bc140c4dda66e1bbfb
ToppCellLPS-IL1RA+antiTNF-Stromal_mesenchymal-Matrix_Fibroblast-Activated_MatrixFB|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

ANK2 ADGRB3 LRP1 LAMB1 RYR2

1.77e-05191755b13229bb7f3713a392271aaf5dbae3edd1b9fe5a
ToppCellPCW_07-8.5-Epithelial-Epithelial_airway-epi_proximal_secretory_(0)|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

FREM2 LRP2 LAMB3 CHST9 DNAH7

1.77e-0519175560ff989fe99d243a3d52955223680cdd1f1917a4
ToppCellPCW_10-12-Epithelial-Epithelial_proliferating-epi_proliferating2_(13)|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung

FREM2 ASPM CHST9 KNL1 NMU

1.77e-0519175539220f4a345e328f7fa4fd462a0abeea821b3e02
ToppCellChildren_(3_yrs)-Epithelial-alveolar_epithelial_cell_type_2|Children_(3_yrs) / Lineage, Cell type, age group and donor

FREM2 PRTG ETV5 PPP1R13B MAGI3

1.77e-05191755a0332a4ef629510fb313ec119195c44a3f704a80
ToppCellFetal_29-31_weeks-Epithelial-alveolar_epithelial_cell_type_1/2_(AT1/AT2-like)|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

RANBP17 FREM2 PPP1R13B MAGI3 NMU

1.77e-05191755ca5669bd6f4a17471acae3eb229f845cc2e08efa
ToppCellEpithelial-alveolar_epithelial_cell_type_1/2_(AT1/AT2-like)|World / Lineage, Cell type, age group and donor

RANBP17 FREM2 PPP1R13B MAGI3 NMU

1.77e-05191755d3733c8c4bda70c4390e5601fdda6188a64be944
ToppCellLPS-IL1RA+antiTNF-Stromal_mesenchymal-Matrix_Fibroblast|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

ANK2 ADGRB3 LRP1 LBH LAMB1

1.82e-051927556f4ef24dab544681304b7f8a9dc073e7edaa4cf5
ToppCellPCW_07-8.5-Epithelial-Epithelial_proliferating-epi_proliferating2_(13)|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

FREM2 ASPM LRP2 LAMB3 NMU

1.82e-0519275525378b5e4b0cea8415ff125783511fc25a56fc00
ToppCellLPS_only-Stromal_mesenchymal|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

MYOF ANK2 LRP1 LAMB1 RYR2

1.82e-05192755162d8b5858d150ecbbd1c9bf2b19c6c9cd50a158
ToppCellPCW_07-8.5-Epithelial-Epithelial_alveolar-distal|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

FREM2 LRP2 ETV5 LAMB3 CHST9

1.82e-05192755b7c01e12b3e9be960a741b08835f1dfff65d0d47
ToppCellLPS_only-Stromal_mesenchymal-Matrix_Fibroblast|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

MYOF ANK2 LRP1 LAMB1 RYR2

1.82e-05192755ee085e04d5dcfb657522484ed20b8c1ddeccfe0c
ToppCellFetal_29-31_weeks-Epithelial-alveolar_epithelial_cell_type_2|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

RANBP17 FREM2 ETV5 PPP1R13B MAGI3

1.82e-05192755fb2f0e897228f808d9ff734ad05e9b49dc38fa50
ToppCellLPS-IL1RA-Stromal_mesenchymal-Matrix_Fibroblast-MatrixFB|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

MYOF ANK2 LRP1 LAMB1 RYR2

1.82e-05192755deeecd26972241846b4cb998edf0c7a87ff0c4df
ToppCellnucseq-Epithelial-Epithelial_Alveolar-AT2-AT2|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

FREM2 PRTG LRP2 ETV5 MAGI3

1.87e-05193755fd4d3c0d7caf8a2fff5b3d901fc28d19a8163cdf
ToppCellnucseq-Epithelial-Epithelial_Alveolar-AT2|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

FREM2 PRTG LRP2 ETV5 MAGI3

1.87e-05193755f3cc7cfdbc164a4ed42f87647111522b7d393bcb
ToppCellPND01-03-samps-Mesenchymal|PND01-03-samps / Age Group, Lineage, Cell class and subclass

LRP1 LBH LAMB1 PTCH1 AKAP12

1.91e-051947554f9bd0ded0dde1df885850714f29e73e992539a5
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

IVNS1ABP FREM2 LAMB1 PLCL1 DNAH7

1.91e-0519475593c68c31e39fa44c1d05d7d4997f4f086da4e738
ToppCellFetal_29-31_weeks-Mesenchymal-matrix_fibroblast_1_cell-D062|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

ADGRB3 LBH LAMB1 PTCH1 RYR2

1.91e-0519475535f132cc38ac133be01834ed0946188aa0757eb4
ToppCellPCW_07-8.5-Epithelial-Epithelial_airway-epi_proximal_progenitor2_(4)|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

FREM2 LRP2 LAMB3 CHST9 DNAH7

1.91e-051947556b286992d4bb56013c0ea5a7601d3476d806175a
ToppCellLPS-antiTNF-Stromal_mesenchymal-Matrix_Fibroblast-Activated_MatrixFB|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

MYOF ANK2 ADGRB3 LRP1 LAMB1

1.91e-0519475589b706af2b25991fc2707eb24f49ba6ff3ae01f7
ToppCellPCW_07-8.5-Epithelial-Epithelial_airway|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

FREM2 LRP2 LAMB3 CHST9 DNAH7

1.91e-05194755f95c8dc242c9aebcadfe61b1ed033349cb7e5a88
ToppCell5'-Parenchyma_lung-Mesenchymal-Fibroblastic-fibroblastic_type_2-Alveolar_fibroblasts-Alveolar_fibroblasts_L.2.1.1.0|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

ADGRB3 LRP1 LBH LAMB1 RYR2

1.96e-05195755df409f94f4e83be89f7a608058ee07ce3ce3a149
ToppCell5'-Parenchyma_lung-Mesenchymal-Fibroblastic-fibroblastic_type_2-Alveolar_fibroblasts|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

ADGRB3 LRP1 LBH LAMB1 RYR2

1.96e-051957554243190ad291d56694e2155954dbaa879c9d3844
ToppCellwk_15-18-Epithelial-Distal_epithelial-type_II_pneumocyte|wk_15-18 / Celltypes from embryonic and fetal-stage human lung

FREM2 NELL2 ETV5 PPP1R13B LAMB3

1.96e-051957550e3aac1b1a1fd483f5fb9a394eb90c0e1ce63542
ToppCellwk_20-22-Epithelial-Distal_epithelial-type_I_pneumocyte|wk_20-22 / Celltypes from embryonic and fetal-stage human lung

RANBP17 FREM2 LAMB3 MAGI3 NMU

2.01e-05196755e24a7aaf41793abba66c1189d933ca05b14c1af9
ToppCellTracheal-10x5prime-Stromal-Peri/Epineurial_|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

LRP1 LAMB1 GRIK3 PTCH1 AKAP12

2.06e-051977552cb1f557ce1400398975de94638126b4522567f3
ToppCellmild-Treg|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

GBP5 EPC1 LBH PLCL1 FHIP2A

2.06e-0519775539800e6e83f2d333b753d121c7aeb2912b91faa2
ToppCell10x_3'_v3-tissue-resident_(10x_3'_v3)-myeloid-myeloid_monocytic-monocyte|tissue-resident_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

ANK2 ADGRB3 CHST9 GRIK3 AKAP12

2.06e-05197755b2f4d7c301c0b24003374923b31d6d058e40b213
ToppCellLPS_IL1RA_TNF-Mesenchymal_fibroblastic-Fibroblasts-Diff_MatrixFB|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type

MYOF LRP1 LBH LAMB1 AKAP12

2.11e-051987550a4b19c3d5e65ecd24fc2ce80ac5276c813282c7
ToppCellCOVID-19-lung-Fibroblast|COVID-19 / Disease (COVID-19 only), tissue and cell type

ADGRB3 LRP1 LBH LAMB1 RYR2

2.11e-051987553ec01a55ade5e1627258cc3cfebb2c3207a4cb43
ToppCellAdult-Mesenchymal|Adult / Lineage, Cell type, age group and donor

ANK2 ADGRB3 LAMB1 AKAP12 RYR2

2.11e-0519875526e55b409db2a1637c95fae7c54b0abea1ef550c
ToppCellParenchymal-NucSeq-Epithelial-Epi_alveolar-AT2|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

FREM2 PRTG LRP2 ETV5 PPP1R13B

2.11e-051987552e2a4e1756bba6f4fbe529559a97d2993c890b4b
ToppCellCOVID-19-lung-Fibroblast|lung / Disease (COVID-19 only), tissue and cell type

ANK2 ADGRB3 LBH LAMB1 RYR2

2.11e-05198755df3de77216f5c5d6141ec44d01c56b942f611838
ToppCellwk_15-18-Epithelial-Airway_epithelial_progenitor|wk_15-18 / Celltypes from embryonic and fetal-stage human lung

FREM2 NELL2 PPP1R13B LAMB3 MAGI3

2.11e-05198755c477405b093f4e5374e57bcacf1fb204a0f7eb3b
ToppCellsevere-Treg|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

GBP5 EPC1 LBH PLCL1 FHIP2A

2.11e-051987554935b40fc848037a06055f30d90bde940b9d5321
ToppCellBronchial-NucSeq-Epithelial-Epi_alveolar|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

RANBP17 FREM2 LRP2 PPP1R13B MAGI3

2.16e-05199755725610310e5c5fd7120c0be9acb55bf152026ddd
ToppCellMesenchymal|World / Lineage, Cell type, age group and donor

ADGRB3 LBH LAMB1 AKAP12 RYR2

2.16e-051997554bac110c2b3609f6ee5d0e3275da0824a6240270
ToppCellLPS_only-Mesenchymal_fibroblastic-Fibroblasts-Activated_MatrixFB|LPS_only / Treatment groups by lineage, cell group, cell type

MYOF ANK2 LRP1 LAMB1 AKAP12

2.16e-05199755fde2b65afde69f402f1b7b056eaa266e9fd5b227
ToppCelldistal-1-Epithelial-Proliferating_Basal|1 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

YEATS4 ASPM LAMB3 KNL1 NMU

2.16e-0519975593450257180d918c310bca7b5defc74390c48091
ToppCell3'-Pediatric_IBD-SmallIntestine-Mesenchymal-fibroblastic-Stromal_1_(ADAMDEC1+)|Pediatric_IBD / Celltypes from developing, pediatric, Crohn's, & adult GI tract

LRP1 LAMB1 PTCH1 ADAM28 AKAP12

2.16e-051997556139687a3a5025cb98da4dba0183f95fcae3dc61
ToppCell5'-GW_trimst-2-LargeIntestine-Mesenchymal|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

LAMB1 PTCH1 ADAM28 AKAP12 VCL

2.16e-051997553d8c76e3d05acf72a35ca755b51579fc3ae63562
ToppCellLPS_IL1RA-Mesenchymal_fibroblastic-Fibroblasts-Activated_MatrixFB|LPS_IL1RA / Treatment groups by lineage, cell group, cell type

MYOF ANK2 LRP1 LAMB1 RYR2

2.16e-051997558b86c69aaf60feff53aa782559cfece7342a23de
ToppCell343B-Fibroblasts-Fibroblast-G|343B / Donor, Lineage, Cell class and subclass (all cells)

LRP1 LBH LAMB1 AKAP12 RYR2

2.16e-05199755f4b6c095cbe7a38b310adc49be4069e4d56e6a66
ToppCell343B-Fibroblasts-Fibroblast-G-|343B / Donor, Lineage, Cell class and subclass (all cells)

LRP1 LBH LAMB1 AKAP12 RYR2

2.16e-051997559c6d1c328bfbb6547f4c7bb2a784576a56bd72af
ToppCellILEUM-inflamed-(8)_Fibroblast-(8)_Fibroblasts|(8)_Fibroblast / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)

ANK2 LAMB1 PTCH1 ADAM28 AKAP12

2.16e-05199755615f20bf136dfef53b072667cf0e4df6a1017e05
ToppCellLPS_only-Mesenchymal_fibroblastic-Fibroblasts-Diff_MatrixFB|LPS_only / Treatment groups by lineage, cell group, cell type

MYOF LRP1 LBH LAMB1 AKAP12

2.21e-05200755ab4fda0cc95cb8f80ea9f28745013f3248def820
ToppCellControl_saline-Mesenchymal_fibroblastic|Control_saline / Treatment groups by lineage, cell group, cell type

LRP1 LBH LAMB1 PTCH1 AKAP12

2.21e-0520075564ae5cf6cb4fc94cf1052abd82648f6b8e6445fe
ToppCelldistal-Epithelial-Proliferating_Basal|distal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

YEATS4 ASPM LAMB3 KNL1 NMU

2.21e-0520075525cc494ef831511840d8c02ec1bd086635cc7edd
DrugFoliosidine [2520-38-9]; Up 200; 13uM; HL60; HT_HG-U133A

RANBP17 MYOF LRP2 LBH DOCK6 ADAM28 FBXW7

3.51e-061997372201_UP
Diseaseamyotrophic lateral sclerosis type 15 (implicated_via_orthology)

UBQLN1 UBQLN4

1.81e-053732DOID:0060206 (implicated_via_orthology)
DiseasePrimary microcephaly

RTTN ASPM KNL1

2.16e-0522733C0431350
Diseaseworry measurement

GAPVD1 BBX PLCL1 PTCH1 SLC38A3

4.09e-05154735EFO_0009589
Diseaseunderweight body mass index status

ANK2 ADGRB3

2.15e-049732EFO_0005936
DiseaseVENTRICULAR TACHYCARDIA, CATECHOLAMINERGIC POLYMORPHIC, 1 (disorder)

ANK2 RYR2

2.68e-0410732C1631597
Diseaseurokinase-type plasminogen activator measurement

CHST9 VCL

3.27e-0411732EFO_0010803
DiseaseColorectal Carcinoma

ANK2 ZSCAN5A LRP1 LRP2 LAMB3 GRIK3 AKAP12 FBXW7

3.40e-04702738C0009402
Diseasefrontotemporal dementia (implicated_via_orthology)

UBQLN1 UBQLN4

3.92e-0412732DOID:9255 (implicated_via_orthology)
Diseasemethionine sulfone measurement

SLC7A9 CYP3A43

3.92e-0412732EFO_0800072
Diseaseneurodegenerative disease (implicated_via_orthology)

UBQLN1 UBQLN4 GRIK3 PTCH1

4.68e-04145734DOID:1289 (implicated_via_orthology)
Diseaseserum metabolite measurement

SLC7A9 CYP3A43 LAMB1 PLCL1 ZSCAN25 DOCK6 C2orf78 SLC45A4 ARMH4

5.28e-04945739EFO_0005653
Diseaserisk-taking behaviour

PRTG GAPVD1 UBQLN4 PPP1R13B REST PTCH1 RYR2 ARMH4

5.94e-04764738EFO_0008579
DiseaseAutosomal recessive primary microcephaly

ASPM KNL1

6.21e-0415732cv:C3711387
Diseaseprimary autosomal recessive microcephaly (is_implicated_in)

ASPM KNL1

7.08e-0416732DOID:0070296 (is_implicated_in)
Diseaseurate measurement, bone density

RANBP17 GBP5 ADGRB3 MAGI3 KAT6B SLC38A3 AKAP12

8.51e-04619737EFO_0003923, EFO_0004531
Diseasemetabolonic lactone sulfate measurement

CYP3A43 ZSCAN25

1.00e-0319732EFO_0800659
Diseasediastolic blood pressure, systolic blood pressure

GAPVD1 ANK2 LRP1 DNAH7 RYR2 SLC45A4 FBXW7

1.34e-03670737EFO_0006335, EFO_0006336
DiseaseAutosomal Recessive Primary Microcephaly

ASPM KNL1

1.35e-0322732C3711387
Diseaseneurotic disorder

BBX GRIK3 PTCH1

2.03e-03101733EFO_0004257
Diseaseneutrophil count

BBX DOCK8 UBQLN4 LBH MAGI3 PLCL1 REST DOCK6 AKAP12 SLC45A4

2.08e-0313827310EFO_0004833
DiseasePigmented Basal Cell Carcinoma

PTCH1 FBXW7

2.19e-0328732C1368275
DiseaseChild Development Disorders, Specific

DOCK8 LRP2

2.35e-0329732C0085997
DiseaseChild Development Deviations

DOCK8 LRP2

2.35e-0329732C0085996
DiseaseCarcinoma, Basal Cell

PTCH1 FBXW7

2.35e-0329732C4721806

Protein segments in the cluster

PeptideGeneStartEntry
EIMSEVMAQRQPMKP

EPC1

281

Q9H2F5
MDKNVPQLPQDEMIV

BDP1

2456

A6H8Y1
LGPVMKMEPLNNLQV

AP2B1

791

P63010
EMPQLNFGMADPTQM

BBX

191

Q8WY36
AHQPEMVMVLKEVQP

C2orf78

241

A6NCI8
MVMVLKEVQPTNVLP

C2orf78

246

A6NCI8
PQMVKAVQPQEMSQM

ADAM28

716

Q9UKQ2
MNPPVMDQFNMNLEQ

ADGRB3

1351

O60242
GVKSQEMVMEQAIPP

AKAP12

1146

Q02952
PQLVVSEDPMMMSAV

ARMH4

66

Q86TY3
MEEITNPLQAIQMVM

ASPM

3456

Q8IZT6
MMPMILTVFLSNNEQ

PPP1R13B

1

Q96KQ4
VMFENEQMVMPGDPV

ATG2B

906

Q96BY7
EQMVMPGDPVEMTEF

ATG2B

911

Q96BY7
PDVLQQMMSVLMNTI

RANBP17

976

Q9H2T7
LQNMETSPMMDVPSV

KAT6B

1641

Q8WYB5
EEIMVQGMPQEPVNI

ANK2

3916

Q01484
AEPMAVPMMLLNLVE

RENBP

186

P51606
MQVVQKEPVQMELSP

REST

721

Q13127
VVQKEPVQMELSPPM

REST

771

Q13127
KISGDVMNENNPPMM

MAEA

341

Q7L5Y9
MNPQDFKPGAMVLEQ

MAGI3

526

Q5TCQ9
LCFMIMGMLPKPQEQ

NMU

81

P48645
FKGIMQDVQLLVMPQ

NELL2

201

Q99435
MQQDELIEKPMSPMQ

IVNS1ABP

341

Q9Y6Y0
KVPDEHMIPIENLMN

LRP1

546

Q07954
VMMNTQPMEEIGLSP

LBH

21

Q53QV2
IVIIPTNDEQPEMFM

FREM2

1181

Q5SZK8
TPGMMSENEVLNMQL

GAPVD1

526

Q14C86
LVGPEIQVMQMMSPD

DSG4

996

Q86SJ6
IQVMQMMSPDLPIGQ

DSG4

1001

Q86SJ6
LERTVLQQQPIPMMD

PDE6C

751

P51160
NEVLKMEMPSTPQQL

LAMB1

1526

P07942
AAPTPEKEMMLQNLM

KNL1

536

Q8NG31
QMGQKVQLPMETLQE

GBP5

336

Q96PP8
LQMPKMMPENQYPSE

ETV5

201

P41161
MMVMLPQSDACNPES

LCN15

166

Q6UWW0
VMEMGKQPIIFENPM

LRP2

4511

P98164
AVGNEESLMPMIMPN

PRTG

1011

Q2VWP7
EQDPPDAKMLQMVLQ

DOCK6

1921

Q96HP0
VAINQEPPDAKMLQM

DOCK8

1961

Q8NF50
EGQQPMLVIMDPDMI

CYP3A43

76

Q9HB55
QLQMPQMEAEVKATP

CHERP

341

Q8IWX8
MHLQMLMEVVPPEED

SLC7A9

471

P82251
MSGEIIQMSPQMNLI

DNAH7

1716

Q8WXX0
IQMSPQMNLIFEPMD

DNAH7

1721

Q8WXX0
EPTQVKHMMQVIEPQ

FBXW7

261

Q969H0
VQLMQPKAMPVEVLG

KHDC3L

11

Q587J8
LQEVMMEFQGPMPAG

LAMB3

116

Q13751
MNQPCNSMEPRVMDD

DRC3

1

Q9H069
FIGVMEPQLMQTSEM

FHIP2A

391

Q5W0V3
LLEDFILNMQMPQVP

GPR139

86

Q6DWJ6
ILNMQMPQVPDKIIE

GPR139

91

Q6DWJ6
QPPMMVKTDAVINMH

GRIK3

881

Q13003
AMMVPIVEAILQQME

SLC13A5

146

Q86YT5
MSNPVPMPEVQEKFQ

RYR2

4406

Q92736
MDAPPMETLITAMEQ

DHX8

946

Q14562
RVNNMPMMALVNPVY

MIF4GD

116

A9UHW6
QNMMMPIIHYPNEVI

RTN4IP1

61

Q8WWV3
ILMQDMNPGVMSTQP

RTL9

206

Q8NET4
MPLENTTVQQMVFML

RTTN

2021

Q86VV8
MEAPLQTEMVELVPN

SLC38A3

1

Q99624
MAERTMAMPTQIPAD

SEPTIN14

1

Q6ZU15
RMEMEFIGMLPSPNQ

IQCA1L

231

A6NCM1
QMRQLSVIPPMMFDA

NCOR1

396

O75376
AMFNPQLMIQTPKEE

PTCH1

151

Q13635
QDMLGLTKPAMPMQQ

SEC23B

201

Q15437
MQPSEMVMNPKQVFL

CHST9

1

Q7L1S5
MKMAPQNADPESMQV

SLC45A4

1

Q5BKX6
IVAMNFQTPGPMMDL

PLCL1

666

Q15111
MEQFMISMPQELQVL

ZSCAN5DP

86

P0CG00
SNPEMMVQIMENPFV

UBQLN1

181

Q9UMX0
MVQIMENPFVQSMLS

UBQLN1

186

Q9UMX0
MLKEHPEMAEAPQQQ

ZSCAN25

1

Q6NSZ9
PTMMNLVEAQLMNPD

HEATR9

401

A2RTY3
PEQKAGEVINQPMMM

VCL

886

P18206
QFMISMPQELQVLVM

ZSCAN5A

91

Q9BUG6
MPQELQVLVMMNGVQ

ZSCAN5A

96

Q9BUG6
QTPDKPMQMNQALFM

PLCG1

1041

P19174
EMIFQDPTAMMQQLL

YEATS4

141

O95619
LSQIMENPLVQDMMS

UBQLN4

196

Q9NRR5
ENPLVQDMMSNPDLM

UBQLN4

201

Q9NRR5
QFMISMPQELQVLVM

ZSCAN5C

91

A6NGD5
MPQELQVLVMMNGVQ

ZSCAN5C

96

A6NGD5
LMQLTEEPQNSMPDI

MYOF

761

Q9NZM1