Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionhistone binding

NAP1L3 SBNO1 BPTF

2.23e-03265203GO:0042393
Domain-

TXNDC2 EEF1G

7.45e-031222023.40.30.10
DomainThioredoxin-like_fold

TXNDC2 EEF1G

8.67e-03132202IPR012336
Pubmed

Synthetic Lethal and Resistance Interactions with BET Bromodomain Inhibitors in Triple-Negative Breast Cancer.

PNN ZNF532 SBNO1 BPTF EEF1G POLR3D RBM25

1.43e-06101421732416067
Pubmed

Elf5-centered transcription factor hub controls trophoblast stem cell self-renewal and differentiation through stoichiometry-sensitive shifts in target gene networks.

PNN BPTF RBM25

3.13e-0510221326584622
Pubmed

MECP2 directly interacts with RNA polymerase II to modulate transcription in human neurons.

PNN ZNF532 BPTF EEF1G RBM25 ZBTB38

3.25e-05108221638697112
Pubmed

Structure and evolution of the Smith-Magenis syndrome repeat gene clusters, SMS-REPs.

CCDC144A CCDC144CP

1.40e-042921211997339
Pubmed

Genome-wide CRISPR screen identifies HNRNPL as a prostate cancer dependency regulating RNA splicing.

EHBP1 ZNF532 EVC BPTF MYT1 NBPF1

1.90e-04148921628611215
Pubmed

A novel class of inhibitors that target SRSF10 and promote p53-mediated cytotoxicity on human colorectal cancer cells.

EEF1G RBM25

4.35e-045121234316707
Pubmed

A genome-wide search for loci interacting with known prostate cancer risk-associated genetic variants.

EVC ZNF280B

4.52e-045221222219177
Pubmed

CHK2 kinase promotes pre-mRNA splicing via phosphorylating CDK11(p110).

EEF1G RBM25

5.06e-045521223178491
Cytoband17p11.2

CCDC144A CCDC144CP

2.40e-0315921217p11.2
CytobandEnsembl 112 genes in cytogenetic band chr17p11

CCDC144A CCDC144CP

3.87e-03203212chr17p11
CytobandEnsembl 112 genes in cytogenetic band chr12q24

SBNO1 TBX3

1.53e-02415212chr12q24
ToppCellH1299-infected|H1299 / Cell line, Condition and Strain

PNN BPTF RBM25 WDR62

1.82e-061922149cf8049bdc3e0f81ce69042beac72b08d8f38b4e
ToppCell(01)_IL1RL1+-(2)_GFP_FOXI1|(01)_IL1RL1+ / shred by cell type by condition

PNN SBNO1 BPTF RBM25

2.10e-06199214a2f7d0cabf35b80fe239fae34a77bf9344d5d743
ToppCellBrain_organoid-organoid_Tanaka_cellReport-6m-Neuronal-Intermediate|6m / Sample Type, Dataset, Time_group, and Cell type.

PNN BPTF TBX3 RBM25

2.14e-062002147c261e39ac30b318511373ab7302aa53b8b81b9c
ToppCell390C-Endothelial_cells-Endothelial-E-|Endothelial_cells / Donor, Lineage, Cell class and subclass (all cells)

TBX3 CCDC144A NBPF1

5.81e-05162213fbb0cc2b1434a340dc35058b77c73ea61004c252
ToppCell390C-Endothelial_cells-Endothelial-E|Endothelial_cells / Donor, Lineage, Cell class and subclass (all cells)

TBX3 CCDC144A NBPF1

5.81e-0516221345be019b50e3727fc9d3fad2ff78e74e4f2d746b
ToppCellC_00|World / shred on cell type and cluster

PNN RBM25 ZBTB38

7.81e-05179213da2dadc3266ffebd4a34ac61bfa05fddcadcde4c
ToppCelldroplet-Tongue-nan|Tongue / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SBNO1 BPTF RBM25

9.03e-05188213d62cc37e86b7b186e53aeb7f421c4e5ee28f23bd
ToppCellPCW_13-14-Mesenchymal-Mesenchymal_myocytic-mes_immature_ASM2_(12)|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung

INTS6L RAB38 TBX3

9.18e-051892130abc7a4900cc9033bc1be69b770ccc54a6bf41b4
ToppCellhuman_hepatoblastoma-Tumor_cells|World / Sample and Cell Type and Tumor Cluster (all cells)

EHBP1 BPTF TBX3

9.62e-05192213916fbec1c7ab7969bda711886ac88e877e30c280
ToppCellhuman_hepatoblastoma|World / Sample and Cell Type and Tumor Cluster (all cells)

EHBP1 BPTF TBX3

9.76e-05193213e6a688bc834f845ff64dae1be64f073eec5091a1
ToppCellPBMC_fresh-frozen|World / Compartment, severity and other cell annotations on 10x 3' data (130k)

PNN BPTF RBM25

1.05e-04198213dcc223a0396b8b673e4ed8c6733ec6cd74e9a03a
ToppCell(11)_FOXN4+-(2)_GFP_FOXI1|(11)_FOXN4+ / shred by cell type by condition

SBNO1 BPTF RBM25

1.05e-0419821376d40b8c2f8399725b3a62ee2ae0896559cf91eb
ToppCell(05)_Secretory-(2)_GFP_FOXI1|(05)_Secretory / shred by cell type by condition

SBNO1 BPTF RBM25

1.07e-04199213d72d87e1e530ed894c0ad5e7b5b2b1d6b59fa098
ToppCellmild-low-quality_cells|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

PNN BPTF RBM25

1.07e-04199213f0b0097df0026496470a80d8cc9375ffd8389b00
ToppCell(04)_Interm._basal>secr.-(2)_GFP_FOXI1|(04)_Interm._basal>secr. / shred by cell type by condition

SBNO1 BPTF RBM25

1.07e-0419921353ca3861f9e00dab3f3fbefb0837857ee39ab084
ToppCellmild|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

PNN BPTF RBM25

1.08e-0420021312f1685ce8f218433068e090c9d839cd5a1910bf
ToppCellCOVID-19|World / Disease, condition lineage and cell class

PNN BPTF RBM25

1.08e-042002137dec470c379cd89f05a0f37c8628b21f136e52f0
ComputationalNeighborhood of RBBP6

PNN BPTF RBM25

9.15e-0570143GNF2_RBBP6
Diseaseinfant head circumference

SBNO1 ZBTB38

4.10e-0515192EFO_0004577
Diseasehip circumference

INTS6L TXNDC2 ZBTB38

1.26e-03338193EFO_0005093
Diseaseprostate carcinoma

EHBP1 EVC ZNF280B ZBTB38

2.23e-03891194EFO_0001663
Diseaseserum gamma-glutamyl transferase measurement

EHBP1 SBNO1 BPTF RBM25

2.44e-03914194EFO_0004532
DiseasePolydactyly

EVC TBX3

2.55e-03117192C0152427
DiseaseMalignant neoplasm of breast

EHBP1 ZNF532 SBNO1 TBX3

4.37e-031074194C0006142
Diseaseblood phosphate measurement

RAB38 SBNO1

5.53e-03174192EFO_0010972
Diseaseprostate specific antigen measurement

TBX3 ZBTB38

6.43e-03188192EFO_0004624
DiseaseHypermetropia, Myopia

BPTF ZBTB38

6.50e-03189192HP_0000540, HP_0000545

Protein segments in the cluster

PeptideGeneStartEntry
MEQSCEEEKEPEPQK

ZNF280B

1

Q86YH2
EPEMAKDCDREDIPI

CCDC144CP

201

Q8IYA2
SDSDKPCKEEPMEVD

BPTF

1131

Q12830
KREEPMEEEEEPEQK

RBM25

596

P49756
MEEEEEPEQKPCLKP

RBM25

601

P49756
ECDLMESIEPDVVKP

RAB38

181

P57729
VDCEPMVIDKLPFDK

INTS6L

316

Q5JSJ4
EPEMEFEIEPDKECK

PNN

426

Q9H307
REMPKAEEKEVPEDS

NBPF1

731

Q3BBV0
EPEMAKDCDREDIPI

CCDC144B

251

Q3MJ40
KKDMSPPFICEETDE

EHBP1

706

Q8NDI1
EKKAAAPAPEEEMDE

EEF1G

251

P26641
QMSKDKEAVDECEPP

EVC

91

P57679
EPEMAKDCDREDIPI

CCDC144A

251

A2RUR9
TMKVPVVKEDDEPEE

SBNO1

216

A3KN83
EEPRDEEEEAKMKAP

POLR3D

221

P05423
KTMEPEEEVEDDPKV

TBX3

91

O15119
CMEATPEVKEDPKEV

NAP1L3

241

Q99457
DEKIEVDDPPDKEDM

ZNF532

141

Q9HCE3
KPEEETMEFPEGDKV

TXNDC2

436

Q86VQ3
DLEEECEPEEMLKTP

WDR62

801

O43379
FEEEETKEMPKLQCE

ZBTB38

971

Q8NAP3
TKDDKEDPELMKCPV

MYT1

881

Q01538