Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
Domain	Mib_Herc2	MIB2 HECTD1	9.50e-05	4	75	2	IPR010606
Domain	MIB_HERC2	MIB2 HECTD1	9.50e-05	4	75	2	PS51416
Domain	MIB_HERC2	MIB2 HECTD1	9.50e-05	4	75	2	PF06701
Domain	-	CDKN2B ASB18 AKAP13 MIB2 HECTD1 NOTCH4	4.83e-04	248	75	6	1.25.40.20
Domain	Ankyrin_rpt-contain_dom	CDKN2B ASB18 AKAP13 MIB2 HECTD1 NOTCH4	5.48e-04	254	75	6	IPR020683
Domain	Ank	CDKN2B ASB18 MIB2 HECTD1 NOTCH4	2.24e-03	228	75	5	PF00023
Domain	ANK	CDKN2B ASB18 MIB2 HECTD1 NOTCH4	3.38e-03	251	75	5	SM00248
Domain	ANK_REPEAT	CDKN2B ASB18 MIB2 HECTD1 NOTCH4	3.50e-03	253	75	5	PS50088
Domain	ANK_REP_REGION	CDKN2B ASB18 MIB2 HECTD1 NOTCH4	3.56e-03	254	75	5	PS50297
Domain	Spectrin	SYNE3 SPTBN2	3.81e-03	23	75	2	PF00435
Domain	GUANYLATE_KINASE_2	MAGI2 TJP2	3.81e-03	23	75	2	PS50052
Domain	GUANYLATE_KINASE_1	MAGI2 TJP2	3.81e-03	23	75	2	PS00856
Domain	Ankyrin_rpt	CDKN2B ASB18 MIB2 HECTD1 NOTCH4	4.06e-03	262	75	5	IPR002110
Domain	Guanylate_kin	MAGI2 TJP2	4.86e-03	26	75	2	PF00625
Domain	GK/Ca_channel_bsu	MAGI2 TJP2	4.86e-03	26	75	2	IPR008145
Domain	Guanylate_kin-like_dom	MAGI2 TJP2	4.86e-03	26	75	2	IPR008144
Domain	GuKc	MAGI2 TJP2	4.86e-03	26	75	2	SM00072
Domain	HECT	UBR5 HECTD1	5.23e-03	27	75	2	PF00632
Domain	HECTc	UBR5 HECTD1	5.23e-03	27	75	2	SM00119
Domain	HECT_dom	UBR5 HECTD1	5.23e-03	27	75	2	IPR000569
Domain	HECT	UBR5 HECTD1	5.23e-03	27	75	2	PS50237
Domain	Spectrin_repeat	SYNE3 SPTBN2	6.02e-03	29	75	2	IPR002017
Domain	P-loop_NTPase	MAGI2 ABCB9 TDRD9 KIF26B TJP2 RNF213 MCM6 DDX51 DNAH9	6.75e-03	848	75	9	IPR027417
Domain	Spectrin/alpha-actinin	SYNE3 SPTBN2	7.30e-03	32	75	2	IPR018159
Domain	SPEC	SYNE3 SPTBN2	7.30e-03	32	75	2	SM00150
Pathway	REACTOME_ANTIGEN_PROCESSING_UBIQUITINATION_PROTEASOME_DEGRADATION	ASB18 FBXO10 KLHL21 FBXW4 RNF213 PSMB11 MIB2 HECTD1	2.85e-05	299	58	8	MM15711
Pathway	REACTOME_ANTIGEN_PROCESSING_UBIQUITINATION_PROTEASOME_DEGRADATION	ASB18 FBXO10 KLHL21 FBXW4 RNF213 PSMB11 MIB2 HECTD1	3.52e-05	308	58	8	M1070
Pathway	REACTOME_CLASS_I_MHC_MEDIATED_ANTIGEN_PROCESSING_PRESENTATION	ASB18 FBXO10 KLHL21 FBXW4 RNF213 PSMB11 MIB2 HECTD1	7.51e-05	343	58	8	MM15712
Pathway	REACTOME_CLASS_I_MHC_MEDIATED_ANTIGEN_PROCESSING_PRESENTATION	ASB18 FBXO10 KLHL21 FBXW4 RNF213 PSMB11 MIB2 HECTD1	1.56e-04	381	58	8	M1066
Pubmed	A dual-activity topoisomerase complex regulates mRNA translation and turnover.	DACT1 NCOR2 EHBP1L1 SYNE3 IER5L KLHL21 CSPG4 CTDP1 CPSF1 PAPLN PFAS AKAP13 MIB2 HECTD1 ELL C6orf132 AHNAK2	3.07e-10	1105	78	17	35748872
Pubmed	Functional proteomics establishes the interaction of SIRT7 with chromatin remodeling complexes and expands its role in regulation of RNA polymerase I transcription.	IRS4 UBR5 SPTBN2 TJP2 CPSF1 PFAS MCM6 DDX51 ECPAS HECTD1	2.03e-06	653	78	10	22586326
Pubmed	Prediction of the coding sequences of unidentified human genes. VII. The complete sequences of 100 new cDNA clones from brain which can code for large proteins in vitro.	SPTBN2 PFAS ECPAS DNAH9 NACAD	3.85e-06	104	78	5	9205841
Pubmed	Identification of a recurrent transforming UBR5-ZNF423 fusion gene in EBV-associated nasopharyngeal carcinoma.	UBR5 ZNF423	4.97e-06	2	78	2	23878065
Pubmed	PDGF-B-driven gliomagenesis can occur in the absence of the proteoglycan NG2.	PDGFB CSPG4	4.97e-06	2	78	2	20939912
Pubmed	Wnt/Tcf1 pathway restricts embryonic stem cell cycle through activation of the Ink4/Arf locus.	CDKN2B TCF7	1.49e-05	3	78	2	28346462
Pubmed	Phenotypic and Interaction Profiling of the Human Phosphatases Identifies Diverse Mitotic Regulators.	NCOR2 TBC1D10B IRS4 SPTBN2 WDR55 TRIOBP CPSF1 RNF213 PFAS PPP6R2 PTPN18	2.19e-05	1049	78	11	27880917
Pubmed	Transcription profiling of platelet-derived growth factor-B-deficient mouse embryos identifies RGS5 as a novel marker for pericytes and vascular smooth muscle cells.	PDGFB CSPG4	2.97e-05	4	78	2	12598306
Pubmed	PDGF activation in PGDS-positive arachnoid cells induces meningioma formation in mice promoting tumor progression in combination with Nf2 and Cdkn2ab loss.	CDKN2B PDGFB	2.97e-05	4	78	2	26418719
Pubmed	E3 ubiquitin ligase RNF123 targets lamin B1 and lamin-binding proteins.	ASB18 FBXO10 KIF26B SPTBN2 CPSF1 PRDM13 RNF213 AKAP13 ECPAS	4.02e-05	736	78	9	29676528
Pubmed	Maturation of human dendritic cells is accompanied by functional remodelling of the ubiquitin-proteasome system.	FBXO10 FBXW4 RNF213 MIB2	4.13e-05	85	78	4	19028597
Pubmed	HSF1 phosphorylation establishes an active chromatin state via the TRRAP-TIP60 complex and promotes tumorigenesis.	NCOR2 UBR5 KLHL21 GLYCTK CPSF1 BBS2 PFAS ECPAS NOTCH4	4.85e-05	754	78	9	35906200
Pubmed	Activity-Based Probes for HECT E3 Ubiquitin Ligases.	UBR5 HECTD1	4.94e-05	5	78	2	28425671
Pubmed	A Human Tyrosine Phosphatase Interactome Mapped by Proteomic Profiling.	DUSP12 DNAAF5 UBR5 TJP2 PFAS MCM6 ECPAS PPP6R2 PTPN18 HECTD1	6.37e-05	974	78	10	28675297
Pubmed	K48- and K63-linked ubiquitin chain interactome reveals branch- and length-specific ubiquitin interactors.	NCOR2 UBR5 CPSF1 BBS2 RNF213 PFAS MIB2 MINDY2	6.37e-05	604	78	8	38803224
Pubmed	Activity-based E3 ligase profiling uncovers an E3 ligase with esterification activity.	UBR5 RNF213 MIB2 HECTD1	6.38e-05	95	78	4	29643511
Pubmed	Formation and maturation of the native cerebral collateral circulation.	PDGFB CSPG4	7.40e-05	6	78	2	20346953
Pubmed	CTDP1 regulates breast cancer survival and DNA repair through BRCT-specific interactions with FANCI.	UBR5 CTDP1 RNF213 AKAP13	9.08e-05	104	78	4	31240132
Pubmed	Identifications of novel host cell factors that interact with the receptor-binding domain of the SARS-CoV-2 spike protein.	TBC1D10B PAPLN PFAS AKAP13 MIB2 EXOC7 PPP6R2 PBXIP1	1.06e-04	650	78	8	38777146
Pubmed	Prediction of the coding sequences of mouse homologues of KIAA gene: IV. The complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.	SPTBN2 RNF213 TSPYL5 PFAS EXOC7 PPP6R2 HECTD1	1.22e-04	493	78	7	15368895
Pubmed	Association between polymorphisms in Wnt signaling pathway genes and bone mineral density in postmenopausal Korean women.	TCF7 FRAT2	1.38e-04	8	78	2	20613673
Pubmed	Slug is a direct Notch target required for initiation of cardiac cushion cellularization.	PDGFB NOTCH4	1.38e-04	8	78	2	18663143
Pubmed	A comprehensive proteomics-based interaction screen that links DYRK1A to RNF169 and to the DNA damage response.	NCOR2 TRIOBP TJP2 AHNAK2	1.48e-04	118	78	4	30979931
Pubmed	MECP2 directly interacts with RNA polymerase II to modulate transcription in human neurons.	TBC1D10B VRK1 EHBP1L1 ACO2 ZNF423 SPTBN2 TRIOBP CPSF1 TSPYL5 PBXIP1	1.51e-04	1082	78	10	38697112
Pubmed	A systems-wide screen identifies substrates of the SCFβTrCP ubiquitin ligase.	UBR5 FBXW4 PFAS AKAP13 HECTD1	1.80e-04	232	78	5	25515538
Pubmed	DNA sequence and analysis of human chromosome 9.	CDKN2B FBXO10 FRRS1L SH2D3C TJP2 ECPAS	1.88e-04	370	78	6	15164053
Pubmed	The Catalytically Inactive Mutation of the Ubiquitin-Conjugating Enzyme CDC34 Affects its Stability and Cell Proliferation.	IRS4 ACO2 CPSF1 PFAS MCM6	1.98e-04	237	78	5	29564676
Pubmed	The Notch ligand Delta-like 4 negatively regulates endothelial tip cell formation and vessel branching.	PDGFB CSPG4	2.21e-04	10	78	2	17296941
Pubmed	Ciliary proteins Bbs8 and Ift20 promote planar cell polarity in the cochlea.	SPTBN2 BBS2	2.21e-04	10	78	2	25605782
Pubmed	Common genetic polymorphisms in moyamoya and atherosclerotic disease in Europeans.	CDKN2B PDGFB	2.70e-04	11	78	2	20694560
Pubmed	Vascular defects in a mouse model of hypotrichosis-lymphedema-telangiectasia syndrome indicate a role for SOX18 in blood vessel maturation.	PDGFB CSPG4	2.70e-04	11	78	2	19429912
Pubmed	Genome-wide association study of clinical dimensions of schizophrenia: polygenic effect on disorganized symptoms.	KIF26B CTDP1	2.70e-04	11	78	2	23212062
Pubmed	Defining the membrane proteome of NK cells.	NCOR2 EHBP1L1 SYNE3 UBR5 RNF213 AKAP13 DDX51 ECPAS EXOC7 APOBR	2.79e-04	1168	78	10	19946888
Pubmed	GPR124, an orphan G protein-coupled receptor, is required for CNS-specific vascularization and establishment of the blood-brain barrier.	PDGFB CSPG4 NOTCH4	3.22e-04	59	78	3	21421844
Pubmed	Defective valves and abnormal mural cell recruitment underlie lymphatic vascular failure in lymphedema distichiasis.	PDGFB CSPG4	3.23e-04	12	78	2	15322537
Pubmed	Zfp423 controls proliferation and differentiation of neural precursors in cerebellar vermis formation.	ZNF423 GDF10	3.23e-04	12	78	2	17151198
Pubmed	Wnt4 regulates thymic cellularity through the expansion of thymic epithelial cells and early thymic progenitors.	TCF7 PSMB11	3.23e-04	12	78	2	21937690
Pubmed	Large-scale characterization of HeLa cell nuclear phosphoproteins.	NCOR2 TBC1D10B ABCB9 CTDP1 TJP2 CPSF1 DDX51 ECPAS	3.45e-04	774	78	8	15302935
Pubmed	A protein-interaction network of interferon-stimulated genes extends the innate immune system landscape.	DNAAF5 IRS4 UBR5 SPTBN2 TRIOBP TJP2 RNF213 ECPAS EXOC7 PBXIP1 AHNAK2	3.59e-04	1440	78	11	30833792
Pubmed	Platelet-derived growth factor over-expression in retinal progenitors results in abnormal retinal vessel formation.	PDGFB CSPG4	3.81e-04	13	78	2	22880002
Pubmed	Differential gene expression in migrating cortical interneurons during mouse forebrain development.	DACT1 MGAT5B	3.81e-04	13	78	2	20151419
Pubmed	Myc regulates embryonic vascular permeability and remodeling.	CSPG4 TJP2	3.81e-04	13	78	2	19407242
Pubmed	Systematic identification of factors for provirus silencing in embryonic stem cells.	UBR5 TJP2 CPSF1 MCM6	3.99e-04	153	78	4	26365490
Pubmed	The sequence of the human genome.	SYNE3 FBXO10 KIF26B PRDM13 RNF213 LEUTX NOBOX	4.15e-04	603	78	7	11181995
Pubmed	Ex vivo Quantitative Proteomic Analysis of Serotonin Transporter Interactome: Network Impact of the SERT Ala56 Coding Variant.	MAGI2 TBC1D10B UBR5 TJP2 MIB2 PBXIP1	4.18e-04	430	78	6	32581705
Pubmed	Synthetic Lethal and Resistance Interactions with BET Bromodomain Inhibitors in Triple-Negative Breast Cancer.	NCOR2 VRK1 UBR5 WDR55 CPSF1 RNF213 MCM6 ECPAS MED26	4.43e-04	1014	78	9	32416067
Pubmed	Comparative analyses of the Dominant megacolon-SOX10 genomic interval in mouse and human.	PDGFB TRIOBP	4.44e-04	14	78	2	10384052
Pubmed	Autoubiquitination of the 26S proteasome on Rpn13 regulates breakdown of ubiquitin conjugates.	UBR5 ECPAS HECTD1	4.49e-04	66	78	3	24811749
Pubmed	Genetic and Proteomic Interrogation of Lower Confidence Candidate Genes Reveals Signaling Networks in β-Catenin-Active Cancers.	NCOR2 TCF7 ACO2 CPSF1 FAM83D PFAS MCM6 MED26 PPP6R2 HECTD1	4.66e-04	1247	78	10	27684187
Pubmed	Protein interaction network of the mammalian Hippo pathway reveals mechanisms of kinase-phosphatase interactions.	IRS4 UBR5 TJP2 ECPAS PPP6R2 HECTD1	5.07e-04	446	78	6	24255178
Pubmed	Pbx1-dependent control of VMC differentiation kinetics underlies gross renal vascular patterning.	PDGFB CSPG4	5.12e-04	15	78	2	26138478
Pubmed	Genome-wide association study identifies multiple susceptibility loci for pulmonary fibrosis.	AKAP13 NOTCH4	5.12e-04	15	78	2	23583980
Pubmed	Angiopoietin-1 is essential in mouse vasculature during development and in response to injury.	PDGFB CSPG4	5.12e-04	15	78	2	21606590
Pubmed	Radial construction of an arterial wall.	PDGFB CSPG4	5.12e-04	15	78	2	22975322
Pubmed	ARMC5 is part of an RPB1-specific ubiquitin ligase implicated in adrenal hyperplasia.	IRS4 PFAS MCM6 EXOC7	5.42e-04	166	78	4	35687106
Pubmed	A protein interaction landscape of breast cancer.	DNAAF5 UBR5 ACO2 SPTBN2 TSPYL5 ECPAS PBXIP1	5.59e-04	634	78	7	34591612
Pubmed	Enlarged lateral ventricles and aberrant behavior in mice overexpressing PDGF-B in embryonic neural stem cells.	PDGFB CSPG4	5.84e-04	16	78	2	20643125
Pubmed	Dll4 and PDGF-BB convert committed skeletal myoblasts to pericytes without erasing their myogenic memory.	PDGFB CSPG4	6.61e-04	17	78	2	23477786
Pubmed	Large-scale genotyping identifies 41 new loci associated with breast cancer risk.	CDKN2B ELL NOBOX	6.78e-04	76	78	3	23535729
Pubmed	A central chaperone-like role for 14-3-3 proteins in human cells.	TBC1D10B IRS4 KIF26B TJP2 AKAP13 HECTD1 C6orf132 AHNAK2	6.95e-04	861	78	8	36931259
Pubmed	TIF1γ inhibits lung adenocarcinoma EMT and metastasis by interacting with the TAF15/TBP complex.	IRS4 ACO2 PFAS MCM6	7.19e-04	179	78	4	36261009
Pubmed	Single nucleotide polymorphisms in the Wnt and BMP pathways and colorectal cancer risk in a Spanish cohort.	DACT1 TCF7	7.42e-04	18	78	2	20844743
Pubmed	Fbw7 controls neural stem cell differentiation and progenitor apoptosis via Notch and c-Jun.	CSPG4 FBXW4	8.28e-04	19	78	2	20935640
Pubmed	A mutant receptor tyrosine phosphatase, CD148, causes defects in vascular development.	PDGFB NOTCH4	9.19e-04	20	78	2	12588999
Pubmed	Sox17 is indispensable for acquisition and maintenance of arterial identity.	CSPG4 NOTCH4	9.19e-04	20	78	2	24153254
Pubmed	UBE2S interacting with TRIM21 mediates the K11-linked ubiquitination of LPP to promote the lymphatic metastasis of bladder cancer.	UBR5 RNF213	1.01e-03	21	78	2	37422473
Pubmed	Excessive vascular sprouting underlies cerebral hemorrhage in mice lacking αVβ8-TGFβ signaling in the brain.	PDGFB CSPG4	1.01e-03	21	78	2	25406396
Pubmed	Novel interaction partners of Bardet-Biedl syndrome proteins.	BBS2 EXOC7	1.01e-03	21	78	2	18000879
Pubmed	Identification of anchor genes during kidney development defines ontological relationships, molecular subcompartments and regulatory pathways.	MAGI2 DACT1 EHBP1L1 GLYCTK	1.03e-03	197	78	4	21386911
Pubmed	New interaction partners for Nek4.1 and Nek4.2 isoforms: from the DNA damage response to RNA splicing.	IRS4 KLHL21 SH2D3C CPSF1 MINDY2 HECTD1	1.05e-03	513	78	6	25798074
Pubmed	Mammalian APE1 controls miRNA processing and its interactome is linked to cancer RNA metabolism.	TBC1D10B ABCB9 SPTBN2 CTDP1 PFAS MIB2 MED26 EXOC7	1.10e-03	925	78	8	28986522
Pubmed	Klf2 is an essential regulator of vascular hemodynamic forces in vivo.	PDGFB NOTCH4	1.11e-03	22	78	2	17141159
Pubmed	Duffy-null-associated low neutrophil counts influence HIV-1 susceptibility in high-risk South African black women.	VRK1 ABCB9	1.11e-03	22	78	2	21507922
Pubmed	Maternal immune activation leads to defective brain-blood vessels and intracerebral hemorrhages in male offspring.	PDGFB CSPG4	1.11e-03	22	78	2	36314682
Pubmed	Interactomes of Glycogen Synthase Kinase-3 Isoforms.	UBR5 KIF26B PFAS HECTD1	1.28e-03	209	78	4	36779422
Pubmed	Host E3 ligase HUWE1 attenuates the proapoptotic activity of the MERS-CoV accessory protein ORF3 by promoting its ubiquitin-dependent degradation.	IRS4 UBR5 CPSF1 PFAS MCM6 HECTD1	1.29e-03	534	78	6	35032548
Pubmed	N-Terminomics for the Identification of In Vitro Substrates and Cleavage Site Specificity of the SARS-CoV-2 Main Protease.	EHBP1L1 TRIOBP TJP2 PBXIP1 AHNAK2	1.31e-03	360	78	5	33111431
Pubmed	Identification of novel transcribed sequences on human chromosome 22 by expressed sequence tag mapping.	ACO2 TRIOBP	1.33e-03	24	78	2	11258795
Pubmed	Identification and Characterization of MCM3 as a Kelch-like ECH-associated Protein 1 (KEAP1) Substrate.	PFAS MCM6	1.44e-03	25	78	2	27621311
Pubmed	System-Wide Modulation of HECT E3 Ligases with Selective Ubiquitin Variant Probes.	UBR5 HECTD1	1.56e-03	26	78	2	26949039
Pubmed	The Wnt effector transcription factor 7-like 2 positively regulates oligodendrocyte differentiation in a manner independent of Wnt/β-catenin signaling.	TCF7 CSPG4	1.56e-03	26	78	2	25810530
Pubmed	The functional landscape of Hsp27 reveals new cellular processes such as DNA repair and alternative splicing and proposes novel anticancer targets.	TJP2 MCM6 ECPAS HECTD1	1.67e-03	225	78	4	25277244
Pubmed	SCAP knockout in SM22α-Cre mice induces defective angiogenesis in the placental labyrinth.	PDGFB NOTCH4	1.68e-03	27	78	2	33227706
Pubmed	Systematic identification of cancer cell vulnerabilities to natural killer cell-mediated immune surveillance.	EHBP1L1 UBR5 TJP2 DNAH9	1.70e-03	226	78	4	31452512
Pubmed	Cul3-KLHL20 E3 ubiquitin ligase plays a key role in the arms race between HIV-1 Nef and host SERINC5 restriction.	UBR5 MIB2	1.81e-03	28	78	2	35474067
Pubmed	Extra-embryonic vasculature development is regulated by the transcription factor HAND1.	PDGFB NOTCH4	1.81e-03	28	78	2	15073150
Pubmed	UBR-box containing protein, UBR5, is over-expressed in human lung adenocarcinoma and is a potential therapeutic target.	IRS4 UBR5	2.07e-03	30	78	2	32867711
Interaction	TOP3B interactions	DACT1 NCOR2 EHBP1L1 SYNE3 IER5L KLHL21 CSPG4 SPTBN2 CTDP1 CPSF1 PAPLN PFAS AKAP13 MIB2 HECTD1 ELL C6orf132 AHNAK2	9.67e-06	1470	78	18	int:TOP3B
Coexpression	PEREZ_TP53_TARGETS	DACT1 SYNE3 KIF26B KLHL21 BEST4 CSPG4 RNF213 FAM83D TSPYL5 MIB2 EXOC7 NANOS1 C6orf132 AHNAK2	1.10e-05	1201	78	14	M4391
Coexpression	GSE14000_UNSTIM_VS_4H_LPS_DC_TRANSLATED_RNA_UP	IER5L UBR5 TSPYL5 DDX51 HECTD1 FRAT2	2.90e-05	199	78	6	M3337
Coexpression	GSE15750_DAY6_VS_DAY10_EFF_CD8_TCELL_DN	UBR5 FBXW4 BBS2 RNF213 APOBR ELL	2.98e-05	200	78	6	M3579
ToppCell	Sepsis-URO-Lymphocyte-T/NK-Treg\|URO / Disease, condition lineage and cell class	TCF7 PDGFB BEST4 MED26 NANOS1 PBXIP1	1.25e-06	196	78	6	8812d7365fb2b33feff93782d60776e932499a43
ToppCell	PND03-Immune-Immune_Lymphocytic_T/NK-Lymphocytic_T-CD4_T-CD4_T_prolif\|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	TCF7 GLYCTK MCM6 PTPN18 NANOS1	8.87e-06	159	78	5	a5509f0604ef0caef5ed1af83dd89c86686c73cc
ToppCell	Adult-Endothelial-endothelial_cell_of_bronchial_vessel\|Adult / Lineage, Cell type, age group and donor	PDGFB ZNF423 SH2D3C C6orf141 NOTCH4	1.30e-05	172	78	5	ad4ffdb3fc0c560a9cbaa2bc048476cbc43e8fd6
ToppCell	facs-MAT-Fat-3m-Lymphocytic-CD8-positive,_alpha-beta_T_cell\|MAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TCF7 ABCB9 PTPN18 FRAT2 NOBOX	1.45e-05	176	78	5	77c6103639acd0f3d6a2171c5f37a8083b6c2cf0
ToppCell	facs-Brain_Non-Myeloid-Cerebellum-24m-Epithelial-Bergmann_glial_cell\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ABCB9 FRRS1L GLYCTK ADGRA1 GDF10	1.80e-05	184	78	5	f6148e9591e8845cc62668e49fd52755257cdc7e
ToppCell	Adult-Endothelial-capillary_endothelial_cell_(Cap1)-D231\|Adult / Lineage, Cell type, age group and donor	PDGFB ZNF423 SH2D3C MGAT5B NOTCH4	1.84e-05	185	78	5	07f9f38f0739d7c830641723a38385550ac1ac92
ToppCell	Control-Endothelial_cells-Endothelial_cells_(general)\|Control / group, cell type (main and fine annotations)	PDGFB ZNF423 SH2D3C MGAT5B NOTCH4	1.94e-05	187	78	5	fb5bcbc8effdbf0e57fcb71aca990a4aa0d65ce8
ToppCell	droplet-Kidney-KIDNEY-30m-Epithelial-kidney_collecting_duct_principal_cell\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	KIF26B SPTBN2 ADGRA1 C6orf141 C6orf132	2.26e-05	193	78	5	04d47ba7cc1f19f1ffb18d9e68469e75063697cf
ToppCell	Caecum-T_cell-Tfh\|T_cell / Region, Cell class and subclass	TCF7 ABCB9 PDGFB DNAH9 C6orf132	2.43e-05	196	78	5	fe2ee5788028e6b671674f0cc50e2b6379f50976
ToppCell	Biopsy_Other_PF-Epithelial-KRT5-/KRT17+\|Biopsy_Other_PF / Sample group, Lineage and Cell type	CDKN2B BNIP5 KIF26B SPTBN2 AHNAK2	2.68e-05	200	78	5	077e6b9340686de9d0f11b035a8954e1f6a1b790
ToppCell	LPS_anti-TNF-Endothelial-Endothelial-Activated_Alv_Cap\|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type	PDGFB SH2D3C RNF213 MINDY2 INKA1	2.68e-05	200	78	5	bcd1cc96197929d6011903803b6f4ccdcf52b4ce
ToppCell	control\|World / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls	LYPD3 TJP2 HECTD1 C6orf132 AHNAK2	2.68e-05	200	78	5	97f36d2c197e03d93a1fc59949d77ae90f6e6a9a
ToppCell	Smart-start-Cell-Wel_seq-Non-neoplastic-Glial-Neuronal-Astrocyte-Astrocyte-F\|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	ABCB9 BBS2 PAPLN GDF10 PBXIP1	2.68e-05	200	78	5	7a8160e6477708f22e48c609bf8f43f3715dcb03
ToppCell	NS-control\|NS / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	LYPD3 TJP2 HECTD1 C6orf132 AHNAK2	2.68e-05	200	78	5	ecbe89ff95d046155b984c8c150e0b9e7278f839
ToppCell	Parenchymal-10x5prime-Epithelial-Epi_submucosal-gland-SMG_Duct\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	BNIP5 ABCB9 PFAS C6orf141	3.91e-05	108	78	4	9c7f3e25facfb54ef0be45044999bc36438bbea0
ToppCell	Parenchymal-10x5prime-Epithelial-Epi_submucosal-gland\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	BNIP5 ABCB9 PFAS C6orf141	3.91e-05	108	78	4	75d635fc5bb004418db2e1328c24d96b718f10b1
ToppCell	PND07-28-samps-Mesenchymal-Mesenchymal_fibroblast\|PND07-28-samps / Age Group, Lineage, Cell class and subclass	FBXO10 KIF26B FAM83D MED26	8.04e-05	130	78	4	6c6a8b77af08b30b424d4f5def37315d3c6e28b2
ToppCell	PND07-28-samps-Mesenchymal-Mesenchymal_fibroblast-mesenchymal_B\|PND07-28-samps / Age Group, Lineage, Cell class and subclass	FBXO10 KIF26B FAM83D MED26	8.04e-05	130	78	4	0706092f6b466585b3b4808b3b982a122d66cfcf
ToppCell	PBMC-Severe-cDC_8\|Severe / Compartment, Disease Groups and Clusters	DNAAF5 BBS2 DDX51 NOTCH4	1.23e-04	145	78	4	23a9a4fd1934c4a38d9259105c1fdbac459575cb
ToppCell	Substantia_nigra-Macroglia-POLYDENDROCYTE-P1-P1_1-Trf-Oligodendrocyte.Tfr.Ctps_(Ctps)\|Substantia_nigra / BrainAtlas - Mouse McCarroll V32	PDGFB FAM83D MYRFL	1.23e-04	55	78	3	0b62b4f438a493a30bddb99e1eadd20c92704ee9
ToppCell	Substantia_nigra-Macroglia-POLYDENDROCYTE-P1-P1_1-Trf\|Substantia_nigra / BrainAtlas - Mouse McCarroll V32	PDGFB FAM83D MYRFL	1.23e-04	55	78	3	fa556ea954ea868a4b23e410f3b27d69e04794ee
ToppCell	Adult-Immune-enucleated_erythrocyte-D175\|Adult / Lineage, Cell type, age group and donor	SPTBN2 WDR55 MGAT5B FER1L6	1.47e-04	152	78	4	530d5427d8617dcb223d807b73abee0ef89285f3
ToppCell	URO-Lymphocyte-T_NK-Treg\|URO / Disease, Lineage and Cell Type	BEST4 MED26 NANOS1 PBXIP1	1.55e-04	154	78	4	73fe0e26088a1b012902cc062ffbb3e4d2ff09f9
ToppCell	E16.5-samps-Mesenchymal-Myofibroblast-Migrating_MyoFibroblast\|E16.5-samps / Age Group, Lineage, Cell class and subclass	TCF7 PDGFB KIF26B GDF10	1.59e-04	155	78	4	1882fa5fd25f77d6e3ac47b613f6fb3c67d8e50c
ToppCell	facs-Marrow-B-cells-18m-Lymphocytic-NK_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TCF7 ABCB9 ZNF423 PTPN18	1.59e-04	155	78	4	7a16df1a40c7255c24dfb9a921b62871554c7b6d
ToppCell	facs-Marrow-B-cells-18m-Lymphocytic-NK_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TCF7 ABCB9 ZNF423 PTPN18	1.59e-04	155	78	4	f51a12556ca0a3416a6cf0687f908fb4e752fb2f
ToppCell	droplet-Heart-nan-3m-Endothelial-nan\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ABCB9 PAPLN MED26 INKA1	1.67e-04	157	78	4	d85a2f56ae313baa9738e81d2756ce1fe1ba50db
ToppCell	AT1-AT2_cells-Myositis-ILD_01\|World / lung cells shred on cell class, cell subclass, sample id	CDKN2B ASB18 BNIP5 PAPLN	1.71e-04	158	78	4	3bc51cfd37b289cc3e866b54ce55a298e5eff690
ToppCell	Control-Endothelial_cells-Inflamed_endothelial_cells\|Control / group, cell type (main and fine annotations)	PDGFB ZNF423 SH2D3C NOTCH4	1.79e-04	160	78	4	958256e3d3836160763b82bb48f794087918d935
ToppCell	LPS-IL1RA+antiTNF-Lymphocytic_NKT-iNKT/MAIT-T-cells\|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	TBC1D10B TCF7 BEST4 GLYCTK	1.79e-04	160	78	4	5c931e859acf67c1c8664941e0e44d195f8ba75b
ToppCell	AT1-AT2_cells-IPF_01\|World / lung cells shred on cell class, cell subclass, sample id	CDKN2B BNIP5 NANOS1 C6orf132	1.88e-04	162	78	4	57d627259d27f39885bf416d74bcb6656db6e27b
ToppCell	renal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial-Afferent_/_Efferent_Arteriole_Endothelial_Cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	SYNE3 PDGFB SH2D3C NOTCH4	2.06e-04	166	78	4	8e5f2afbeffae5e77fcb29e8fe9f5aa49779b619
ToppCell	severe-CD4+_T_naive\|severe / disease stage, cell group and cell class	TCF7 SYNE3 LYPD3 BBS2	2.11e-04	167	78	4	02a8215fca59c357c1cdaa5738849eacf98c0bcc
ToppCell	facs-Limb_Muscle-forelimb_and_hindlimb-18m-Lymphocytic-T_cell\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TCF7 FBXW4 FAM83D PTPN18	2.16e-04	168	78	4	182f08106ac65ea501e2fb9139d3b44b7c4662c9
ToppCell	3'-GW_trimst-2-LargeIntestine-Epithelial-Tuft-related-BEST4+_epithelial\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	CDKN2B BEST4 CTDP1 APOBR	2.21e-04	169	78	4	1dfaf9a6b433a5ee86a11962af188978c2543278
ToppCell	3'-GW_trimst-2-LargeIntestine-Epithelial-Tuft-related\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	CDKN2B BEST4 CTDP1 APOBR	2.21e-04	169	78	4	3e267ec9f884df326315500dfd751b04a3dd91bd
ToppCell	renal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial-Ascending_Vasa_Recta_Endothelial_Cell_prolif\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	SLC8A2 ZNF423 C6orf141 NOBOX	2.21e-04	169	78	4	7c994653b0d629dfb046755d6b678452de0a15d2
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell-Descending_Thin_Limb_Cell_Type_3\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	MAGI2 ASB18 KIF26B NOBOX	2.26e-04	170	78	4	5d5f208682be21ed58320f5fc083a7898f8712da
ToppCell	10x5'-GI_small-bowel-Lymphocytic_T_CD8-Tem/emra_CD8\|GI_small-bowel / Manually curated celltypes from each tissue	BNIP5 BEST4 C6orf141 DNAH9	2.31e-04	171	78	4	f28684ea0e74a22f4c140658496068e28a6d3605
ToppCell	PND14-Immune-Immune_Myeloid-DC\|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	VRK1 EHBP1L1 PTPN18 APOBR	2.31e-04	171	78	4	8772d6349db24de47f089df2032a80345db7177f
ToppCell	droplet-Lung-3m-Hematologic-lymphocytic-CD4-positive,_alpha-beta_T_cell-CD4-positive,_alpha-beta_T_cell_l9\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	TCF7 ABCB9 FAM83D PTPN18	2.41e-04	173	78	4	da0f1461643294f92e20b5e456a50211a2780a91
ToppCell	356C-Myeloid-Dendritic-cDC_proliferating_2\|Dendritic / Donor, Lineage, Cell class and subclass (all cells)	GLYCTK PAPLN PPP6R2 DNAH9	2.52e-04	175	78	4	7de1023161233b64f11e130881c742f4cf2bff65
ToppCell	PND07-28-samps-Mesenchymal-Myofibroblast-myofibroblast_-_mature_-_DCN\|PND07-28-samps / Age Group, Lineage, Cell class and subclass	DACT1 GDF10 MGAT5B AHNAK2	2.58e-04	176	78	4	08f94b78b27feeb113dbfadbfa7fe34d08b2809b
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell-Glomerular_Capillary_Endothelial_Cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	PDGFB SH2D3C MGAT5B NOTCH4	2.58e-04	176	78	4	dc5a22f9d1347f157bdd93e6e5769b983deccf1a
ToppCell	PND03-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_vascular-VSMC-VSMC_G2M\|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	SLC8A2 CSPG4 FAM83D TSPYL5	2.58e-04	176	78	4	45c6983ab671b0f306e7390320bd84f848e474cc
ToppCell	facs-SCAT-Fat-3m-Lymphocytic-CD8-positive,_alpha-beta_T_cell\|SCAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TCF7 ABCB9 PTPN18 FRAT2	2.63e-04	177	78	4	ffc4c675b25ffe8bd3441ce26dd0984fef4b3b88
ToppCell	Adult-Endothelial-endothelial_cell_of_bronchial_vessel-D175\|Adult / Lineage, Cell type, age group and donor	PDGFB PFAS C6orf141 NOTCH4	2.63e-04	177	78	4	c9f269765c7d5d29caab75910e51645606ed562e
ToppCell	E16.5-Mesenchymal-Mesenchymal_structural-Fibroblastic-AF2-AF2_prolif\|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	MAGI2 SLC8A2 ZNF423 PPP6R2	2.63e-04	177	78	4	30f82b04e48940bfcaf2c22677efe6d57ae3f1a7
ToppCell	droplet-Bladder-BLADDER-1m-Endothelial-nan\|Bladder / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PDGFB CSPG4 BBS2 NOTCH4	2.69e-04	178	78	4	6bef4ef48f649c6e38ae732bc08e6d7814db588b
ToppCell	facs-BAT-Fat-3m-Lymphocytic-T_cell\|BAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TCF7 ABCB9 PTPN18 FRAT2	2.69e-04	178	78	4	7c101e3957ea9b0d4ebf619d1d02e7e64ae28915
ToppCell	Endothelial-A-Donor_05\|World / lung cells shred on cell class, cell subclass, sample id	PDGFB ZNF423 NOTCH4 AHNAK2	2.75e-04	179	78	4	138fd6ba6bdbd0ad01c574168addf720b67a0fea
ToppCell	PND10-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_vascular-Pericyte-Pericyte_prolif\|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	CSPG4 GLYCTK MIB2 NANOS1	2.87e-04	181	78	4	274c0b768925cd5804483303f8c5ebd17a534c41
ToppCell	metastatic_Brain-Fibroblasts-Myofibroblasts\|metastatic_Brain / Location, Cell class and cell subclass	CDKN2B DACT1 FRRS1L GDF10	2.87e-04	181	78	4	bd0b5f74f9c81ec0f1592710774a4fdf33d9d5a9
ToppCell	facs-Brain_Non-Myeloid-Cerebellum_-18m-Epithelial-nan\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ABCB9 FRRS1L ADGRA1 GDF10	2.93e-04	182	78	4	904804813849b7f7f716ba1554d33b07bc0a701e
ToppCell	E18.5-samps-Endothelial-Mature_fetal_endothelial-endothelial_cells_A\|E18.5-samps / Age Group, Lineage, Cell class and subclass	PDGFB SH2D3C RNF213 INKA1	2.93e-04	182	78	4	ea4f6c8f600ffe9f8e0609637b3371a5ac48ca03
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Endothelial-lymphatic_endothelial_cell-lymphatic_endothelial_cell_of_renal_cortex\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	SYNE3 ZNF423 SH2D3C C6orf141	2.93e-04	182	78	4	41b070085edba7a58b81c20aa4942d06f745acf8
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Endothelial-lymphatic_endothelial_cell-lymphatic_endothelial_cell_of_renal_cortex-lymphatic_endothelial_cell_of_renal_cortex\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	SYNE3 ZNF423 SH2D3C C6orf141	2.93e-04	182	78	4	5e9a67b2de0daa4fdc344b10a857d8a901ad810e
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Endothelial-lymphatic_endothelial_cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	SYNE3 ZNF423 SH2D3C C6orf141	2.93e-04	182	78	4	b0fe042c71d6ab8c75abd7ba9d2de00b72d01c0c
ToppCell	facs-Brain_Non-Myeloid-Cerebellum_-18m-Epithelial\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ABCB9 FRRS1L ADGRA1 GDF10	2.93e-04	182	78	4	5d8b7fe18286e27f0f50c5d2d9be56850e2cb8f4
ToppCell	facs-Brain_Non-Myeloid-Cerebellum-3m-Epithelial-Bergmann_glial_cell\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ABCB9 FRRS1L ADGRA1 GDF10	2.99e-04	183	78	4	25c96df8ea0c7bbedbb7699ee84ad6234d19cba8
ToppCell	facs-Brain_Non-Myeloid-Cerebellum_-18m-Epithelial-Bergmann_glial_cell\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ABCB9 FRRS1L ADGRA1 GDF10	2.99e-04	183	78	4	99bb4ceb92f6467f2359a42ab2cff6df18825a30
ToppCell	facs-SCAT-Fat-18m-Lymphocytic-CD8-positive,_alpha-beta_T_cell\|SCAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TCF7 IER5L PTPN18 FRAT2	3.05e-04	184	78	4	f9365feed31e48f3382588bab077f99c5a3f5b04
ToppCell	facs-SCAT-Fat-3m-Lymphocytic-T_cell\|SCAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TCF7 ABCB9 PTPN18 FRAT2	3.05e-04	184	78	4	cdacb61878e0824b8416bf365d89965797208359
ToppCell	facs-Brain_Non-Myeloid-Cerebellum-24m-Epithelial-nan\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ABCB9 FRRS1L ADGRA1 GDF10	3.05e-04	184	78	4	6b0c110d8930df99043c3b99cf4d873985126960
ToppCell	facs-Brain_Non-Myeloid-Cerebellum-24m-Epithelial\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ABCB9 FRRS1L ADGRA1 GDF10	3.05e-04	184	78	4	35928fc5f7bbf8c7b09181a2bd27e22dff42ec16
ToppCell	TCGA-Thryoid-Primary_Tumor-Thyroid_Papillary_Carcinoma-Classical-4\|TCGA-Thryoid / Sample_Type by Project: Shred V9	SPTBN2 WDR55 TJP2 AHNAK2	3.05e-04	184	78	4	d9659d1e4465fec68f48a22edef443f354f6c7cf
ToppCell	facs-Brain_Non-Myeloid-Cerebellum-3m-Epithelial\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ABCB9 FRRS1L ADGRA1 GDF10	3.11e-04	185	78	4	dbbd348714cd16a4948a04648e914b1e71e2a8ef
ToppCell	facs-Brain_Non-Myeloid-Cerebellum-3m-Epithelial-nan\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ABCB9 FRRS1L ADGRA1 GDF10	3.11e-04	185	78	4	bea69058afa5aa927fe15c1f8d46460562ec4dd4
ToppCell	390C-Lymphocytic-CD4_T-cell-Treg_cell_1\|390C / Donor, Lineage, Cell class and subclass (all cells)	IER5L FRAT2 PBXIP1 INKA1	3.18e-04	186	78	4	064b6047215597465bb51a8a1547ef5a226552f9
ToppCell	facs-Mammary_Gland-Mammary_Gland-21m\|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	NCOR2 IER5L LYPD3 PBXIP1	3.18e-04	186	78	4	bd1185592aedebccd1007dbf2dd2f549fcdf9f42
ToppCell	droplet-Fat-Gat-18m-Lymphocytic-T_cell\|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TCF7 ABCB9 TDRD9 PTPN18	3.18e-04	186	78	4	2c1166777b31b802bf88a77acc2838a33c801e76
ToppCell	Control-Endothelial_cells-Endothelial_cells_(other)\|Control / group, cell type (main and fine annotations)	PDGFB ZNF423 SH2D3C NOTCH4	3.18e-04	186	78	4	c6075fe84226b370c5139066793844ad33ae2db1
ToppCell	droplet-Heart-nan-18m-Endothelial-coronary_vascular_endothelial_cell\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PDGFB SH2D3C NOTCH4 INKA1	3.18e-04	186	78	4	49ad01d216860a2bd4d63905a7064471b02f2b37
ToppCell	Fetal_29-31_weeks-Endothelial-alveolar_capillary_endothelial_cell_(Cap2;_aerocyte)-D062\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	PDGFB CSPG4 SH2D3C NOTCH4	3.24e-04	187	78	4	97b2463fb37e7196dd2f92553acf8e7bc3ec40dd
ToppCell	Adult-Endothelial-endothelial_cell_of_lymph_vessel-D175\|Adult / Lineage, Cell type, age group and donor	KIF26B ZNF423 SH2D3C C6orf141	3.24e-04	187	78	4	1e52d3d9d664c813d859b5b75e4c07b218818f95
ToppCell	TCGA-Breast-Primary_Tumor-Breast_Carcinoma-Infiltrating_Lobular_Carcinoma-6\|TCGA-Breast / Sample_Type by Project: Shred V9	ZNF423 SH2D3C PAPLN NOTCH4	3.31e-04	188	78	4	c90669b51e1902fe7726555290c91c92a911df83
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial-Afferent_/_Efferent_Arteriole_Endothelial_Cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	SYNE3 PDGFB SH2D3C NOTCH4	3.31e-04	188	78	4	c2c51c6526defe2600302901159b8abbb58d7595
ToppCell	droplet-Heart-nan-18m-Endothelial-endothelial_cell_of_coronary_artery\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PDGFB SH2D3C NOTCH4 INKA1	3.31e-04	188	78	4	9dfa2e0b73640459cdf88277291e3ab9c33e0217
ToppCell	droplet-Kidney-nan-21m-Epithelial-kidney_collecting_duct_principal_cell\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	KIF26B SPTBN2 C6orf141 C6orf132	3.31e-04	188	78	4	315ce1736e3a84a63a8d5dfa70d411b501cb2532
ToppCell	Control-Endothelial_cells\|Control / group, cell type (main and fine annotations)	PDGFB ZNF423 SH2D3C NOTCH4	3.31e-04	188	78	4	3953b08abfea93468fc8d177bdb16ca7c6ffa1ab
ToppCell	Bronchial-NucSeq-Immune_Lymphocytic-T-T_CD8-MAIT\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	ASB18 TCF7 NANOS1 PBXIP1	3.38e-04	189	78	4	159b0979c93b7d98aaeeb43fba5983a9f67b9c9d
ToppCell	facs-Mammary_Gland-Mammary_Gland-21m-Epithelial\|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	NCOR2 IER5L LYPD3 PBXIP1	3.38e-04	189	78	4	965e0e388251e7318f8b463816dc96ccb4658677
ToppCell	tumor_Lung-Fibroblasts-Pericytes\|Fibroblasts / Location, Cell class and cell subclass	PDGFB CSPG4 SH2D3C NOTCH4	3.38e-04	189	78	4	9c407b17d7945e81e1ae6c18452f5d20fb09d563
ToppCell	Endothelial-A-IPF_01\|World / lung cells shred on cell class, cell subclass, sample id	PDGFB SH2D3C NOTCH4 INKA1	3.38e-04	189	78	4	04b565855f58ca0f343904d04be657b66e109076
ToppCell	IPF-Endothelial-VE_Capillary_A\|World / Disease state, Lineage and Cell class	CDKN2B PDGFB SH2D3C NOTCH4	3.38e-04	189	78	4	ea3aa3ef38f1d405bb527ae383cd12c551a3dd6f
ToppCell	LAM-Endothelial-VasEndo-1\|LAM / Condition, Lineage and Cell class	PDGFB SH2D3C NOTCH4 INKA1	3.38e-04	189	78	4	454e64b1ee93edebbc1576fbf7c3a6db332fa927
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Endothelial-lymphatic_endothelial_cell-lymphatic_endothelial_cell_of_renal_cortex\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	SYNE3 ZNF423 SH2D3C C6orf141	3.44e-04	190	78	4	876bd2eb9ed2624cb23bdcf6b989e4fa34d099e3
ToppCell	3'-Airway_Nasal-Epithelial-Epithelial_transtional-secretory-nasal_mucosa_goblet_cell-Goblet_(nasal)-Goblet_(nasal)_L.0.2.0.2\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	CDKN2B TJP2 FER1L6 C6orf132	3.44e-04	190	78	4	6ea9fa08bd97bedcb21d3654467e7f8dd74c8fd0
ToppCell	IPF-Endothelial-VE_Capillary_A\|IPF / Disease state, Lineage and Cell class	CDKN2B PDGFB SH2D3C NOTCH4	3.44e-04	190	78	4	b4e35cbfe4d43d2cd51f29c3085e4d9b1012e6f0
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Endothelial-lymphatic_endothelial_cell-lymphatic_endothelial_cell_of_renal_cortex-lymphatic_endothelial_cell_of_renal_cortex\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	SYNE3 ZNF423 SH2D3C C6orf141	3.44e-04	190	78	4	be9f36127028f52ca5fc1b32ba15a6c26aad69ac
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Endothelial-lymphatic_endothelial_cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	SYNE3 ZNF423 SH2D3C C6orf141	3.44e-04	190	78	4	09a8855901c3c9332dbaab3e40166485b696d0f1
ToppCell	facs-SCAT-Fat-3m-Endothelial-nan\|SCAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PDGFB SH2D3C NOTCH4 INKA1	3.51e-04	191	78	4	a0018f88f7132477cc467ee15db029a585290595
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial-Afferent_/_Efferent_Arteriole_Endothelial_Cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	SYNE3 PDGFB SH2D3C NOTCH4	3.51e-04	191	78	4	b2c86cde341fe350143658c8a8a4a9edbce3f19b
ToppCell	3'-Airway_Nasal-Epithelial-Epithelial_transtional-secretory-nasal_mucosa_goblet_cell-Goblet_(nasal)-Goblet_(nasal)_L.0.2.0.0\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	CDKN2B TJP2 FER1L6 C6orf132	3.51e-04	191	78	4	cd709bbcd320373468ea7f058ee5fda8a067b5d0
ToppCell	3'-Airway_Nasal-Epithelial-Epithelial_transtional-secretory-nasal_mucosa_goblet_cell\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	CDKN2B TJP2 FER1L6 C6orf132	3.51e-04	191	78	4	14851529025cfc2b665f71ebad04150ec543da7a
ToppCell	facs-SCAT-Fat-3m-Endothelial-endothelial_cell\|SCAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PDGFB SH2D3C NOTCH4 INKA1	3.51e-04	191	78	4	6b9bbf4a63d4e9a8075bb06c2aa644fcf4ee88b8
ToppCell	facs-SCAT-Fat-3m-Endothelial\|SCAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PDGFB SH2D3C NOTCH4 INKA1	3.51e-04	191	78	4	90f0c193dce267a4f1a9b2501f636dafd0a34cf7
ToppCell	5'-Airway_Nasal-Epithelial-Epithelial_transtional-secretory-nasal_mucosa_goblet_cell-Goblet_(nasal)-Goblet_(nasal)_L.0.2.0.3\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	CDKN2B LYPD3 FAM83D C6orf132	3.51e-04	191	78	4	fbd8d337b4444fba8527a614e4a8bfb516ce0f66
ToppCell	3'-Airway_Nasal-Epithelial-Epithelial_transtional-secretory-nasal_mucosa_goblet_cell-Goblet_(nasal)\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	CDKN2B TJP2 FER1L6 C6orf132	3.51e-04	191	78	4	e14b22e882ac92acf8c8b6ee997ef8e799c7a8d5
ToppCell	COVID-19-kidney-AQP1+PLVAP+EC\|COVID-19 / Disease (COVID-19 only), tissue and cell type	PDGFB ZNF423 SH2D3C NOTCH4	3.58e-04	192	78	4	27ff3621e177e7932dd44dd6baa81551ea75a874
Drug	15d-PGJ2; Down 200; 10uM; PC3; HT_HG-U133A	ABCB9 SPTBN2 CTDP1 PPP6R2 PTPN18 MINDY2 PBXIP1	4.25e-06	194	77	7	4455_DN
Disease	migraine disorder	NCOR2 KIF26B TJP2 RNF213 TSPYL5 NOTCH4	3.22e-04	357	76	6	MONDO_0005277
Disease	cup-to-disc ratio measurement	DUSP12 CDKN2B TCF7 EHBP1L1 SYNE3 TRIOBP	8.56e-04	430	76	6	EFO_0006939
Disease	p-tau measurement	DNAAF5 CTDP1 EXOC7	8.62e-04	72	76	3	EFO_0004763
Disease	aspartate aminotransferase measurement	NCOR2 WDR55 RNF213 AKAP13 MCM6 PTPN18 ELL NOTCH4	2.26e-03	904	76	8	EFO_0004736

Protein segments in the cluster

Peptide	Gene	Start	Entry
AQRPGAHAEDARGTL	PTPN18	396	Q99952
HLLRFRAEEGGDPEA	BEST4	441	Q8NFU0
GEGSSREHAALEPRH	ACO2	666	Q99798
DAPDRATHLIAARAG	CTDP1	676	Q9Y5B0
PLADVSNDLGHSGRD	ELL	396	P55199
ARHGELELDIPGAQA	CSPG4	476	Q6UVK1
PRGHRAQENFSEDGD	FBXO10	686	Q9UK96
LSAHDDGAPAGVREV	AKAP13	1201	Q12802
DAHPALDANGAALGR	ADGRA1	326	Q86SQ6
GEEELLRGSAPHAQD	NOBOX	111	O60393
AEALHASGNEVPRGE	NCOR2	721	Q9Y618
AAEPGAGSQHLEVRD	MCM6	6	Q14566
VTEDRDAALGGPREH	INKA1	76	Q96EL1
DAADAARAGGKEAPR	MAGI2	1356	Q86UL8
LSAACGAARRPDEHG	ASB18	256	Q6ZVZ8
ARGGALAEDEPAAAH	KIF26B	1831	Q2KJY2
AADGLQGDRDLQRHP	GDF10	46	P55107
QGDRDLQRHPGDAAA	GDF10	51	P55107
TTPEADDDGRRHGFL	CPSF1	561	Q10570
LAAGDPREEVHGEAQ	ECPAS	521	Q5VYK3
ELHRAGGDLHFPADR	MGAT5B	96	Q3V5L5
AEPRLHAASGAAAAR	NANOS1	191	Q8WY41
FDDLQRLLHGDPGEE	PDGFB	41	P01127
HAILRAAERPGEEGA	FAM83D	66	Q9H4H8
DDLDAGGLAQRLRGH	EHBP1L1	1171	Q8N3D4
HGRVGINTDAPDEAL	MYRFL	421	Q96LU7
HRAAEDRELSVGPGE	PSMB11	271	A5LHX3
HAGPEGSRLERDEND	MED26	201	O95402
EALNDKHGPLAGRDD	EXOC7	341	Q9UPT5
HEASRDEEPRLTGGA	LYPD3	286	O95274
HAPRLSLEGAARGAA	C6orf132	1116	Q5T0Z8
LLRHGANPDLRDEDG	HECTD1	446	Q9ULT8
AAGGRDFPAHRAVLA	KLHL21	41	Q9UJP4
AELASPLNEADGHRG	BBS2	361	Q9BXC9
ADLGPARRGGEDSDH	BNIP5	196	P0C671
AAAPRAGELLGEAAQ	DACT1	81	Q9NYF0
GAEDNLPDRDALRAA	GLYCTK	141	Q8IVS8
AREEVAGAEDLPHAG	C6orf141	106	Q5SZD1
EGAEAGAHGRARALL	DDX51	21	Q8N8A6
ARGDTGADEAVPRHD	FRRS1L	46	Q9P0K9
PVDLAEERGHRDVAG	CDKN2B	116	P42772
LNRRPLGVFAGHDED	FBXW4	151	P57775
AAENADGEPGADRRL	DNAH9	11	Q9NYC9
CGAALAPHLDDALRA	DNAAF5	156	Q86Y56
FGGAAAVAEPDHLRE	DUSP12	36	Q9UNI6
KPAGLARAAAAAHGD	PRDM13	296	Q9H4Q3
GGGDAEAREPAARHQ	IER5L	96	Q5T953
QRFLDGDHGPVARDD	KIF28P	611	B7ZC32
DGKASLEAHRDAPGA	PPP6R2	676	O75170
AGARAGDDDPHRLLQ	FRAT2	166	O75474
TNHRGRSPLDLAAEG	MIB2	766	Q96AX9
GAARGPHRARAFDED	IRS4	681	O14654
QEGPRGDLVHDDASI	FER1L6	41	Q2WGJ9
HELGTAGDAGARPDL	MINDY2	121	Q8NBR6
LEAHRGEAGPGDAES	SYNE3	671	Q6ZMZ3
REDENPHDGELTFLG	TDRD9	581	Q8NDG6
AHGDRRGEEAAPESL	RNF113B	76	Q8IZP6
AARELRDQAGLAPAD	NOTCH4	1791	Q99466
KDPAGHRDDLARALG	TRIOBP	1596	Q9H2D6
HDGSLAPDHLEGRVD	ABCB9	491	Q9NP78
DLHDPSRDGNLGLAV	AHNAK2	4676	Q8IVF2
EEQERSLEAGPRHAG	APOBR	596	Q0VD83
DLPELGLEHRAEDGH	RNF213	3471	Q63HN8
LERGLDHDFGPSRDR	TJP2	221	Q9UDY2
LQDASRGDPAHAGLA	PBXIP1	416	Q96AQ6
GELTREANALAAGHP	SPTBN2	1016	O15020
QRALGAAAAGPELAE	SPTBN2	1551	O15020
ERGAEGDLAPERLHA	PAPLN	256	O95428
ARGLAPLHWADDDGN	PFAS	1251	O15067
PHDGGDRPSAEARQD	TBC1D10B	791	Q4KMP7
AGARGEAEALGREHA	TCF7	76	P36402
DAHNGVAPSRRGDLE	VRK1	231	Q99986
FHPARDLLAAGDVDG	WDR55	46	Q9H6Y2
RDVHSERAAGEPEAG	SH2D3C	166	Q8N5H7
RAHRCPGDGDDDPQL	ZNF423	86	Q2M1K9
AHGRENGADSILDLG	UBR5	2451	O95071
GLALRARAAGDHGQA	TSPYL5	86	Q86VY4
RLLGSQDHGDDPAER	nan	31	Q8N3U1
GISDANDHDLREPSG	LEUTX	106	A8MZ59
HAADASRRAAPAEGA	SLC8A2	371	Q9UPR5
RTALRDQEGGHASPD	NACAD	136	O15069