Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionvoltage-gated sodium channel activity

SCN11A SCN1A SCN2A SCN3A SCN5A SCN8A SCN9A

4.04e-1226737GO:0005248
GeneOntologyMolecularFunctionsodium channel activity

SCN11A SCN1A SCN2A SCN3A SCN5A SCN8A SCN9A

7.63e-1052737GO:0005272
GeneOntologyMolecularFunctionsodium ion binding

SCN1A SCN2A SCN3A SCN8A SCN9A

1.11e-0914735GO:0031402
GeneOntologyMolecularFunctionalkali metal ion binding

SCN1A SCN2A SCN3A SCN8A SCN9A

3.52e-0826735GO:0031420
GeneOntologyMolecularFunctionmonoatomic cation channel activity

SCN11A SCN1A SCN2A SCN3A SCN5A SCN8A SCN9A KCNIP1 RYR1 RYR3 ITPR2

4.51e-083437311GO:0005261
GeneOntologyMolecularFunctionmonoatomic ion channel activity

SCN11A SCN1A SCN2A SCN3A SCN5A SCN8A SCN9A KCNIP1 RYR1 RYR3 GABRA1 ITPR2

9.74e-084597312GO:0005216
GeneOntologyMolecularFunctionchannel activity

SCN11A SCN1A SCN2A SCN3A SCN5A SCN8A SCN9A KCNIP1 RYR1 RYR3 GABRA1 ITPR2

4.12e-075257312GO:0015267
GeneOntologyMolecularFunctionpassive transmembrane transporter activity

SCN11A SCN1A SCN2A SCN3A SCN5A SCN8A SCN9A KCNIP1 RYR1 RYR3 GABRA1 ITPR2

4.20e-075267312GO:0022803
GeneOntologyMolecularFunctionmetal ion transmembrane transporter activity

SCN11A SCN1A SCN2A SCN3A SCN5A SCN8A SCN9A KCNIP1 RYR1 RYR3 ITPR2

9.41e-074657311GO:0046873
GeneOntologyMolecularFunctionsodium ion transmembrane transporter activity

SCN11A SCN1A SCN2A SCN3A SCN5A SCN8A SCN9A

3.03e-06171737GO:0015081
GeneOntologyMolecularFunctionmonoatomic cation transmembrane transporter activity

SCN11A ATP8A1 SCN1A SCN2A SCN3A SCN5A SCN8A SCN9A KCNIP1 RYR1 RYR3 ITPR2

4.75e-066647312GO:0008324
GeneOntologyMolecularFunctionmonoatomic ion transmembrane transporter activity

SCN11A ATP8A1 SCN1A SCN2A SCN3A SCN5A SCN8A SCN9A KCNIP1 RYR1 RYR3 GABRA1 ITPR2

5.27e-067937313GO:0015075
GeneOntologyMolecularFunction5-diphosphoinositol pentakisphosphate 1-kinase activity

PPIP5K1 PPIP5K2

1.32e-052732GO:0033857
GeneOntologyMolecularFunctioninorganic cation transmembrane transporter activity

SCN11A SCN1A SCN2A SCN3A SCN5A SCN8A SCN9A KCNIP1 RYR1 RYR3 ITPR2

1.63e-056277311GO:0022890
GeneOntologyMolecularFunctioninorganic molecular entity transmembrane transporter activity

SCN11A SCN1A SCN2A SCN3A SCN5A SCN8A SCN9A KCNIP1 RYR1 RYR3 GABRA1 ITPR2

1.80e-057587312GO:0015318
GeneOntologyMolecularFunctionintracellularly gated calcium channel activity

RYR1 RYR3 ITPR2

3.68e-0518733GO:0015278
GeneOntologyMolecularFunctioninositol hexakisphosphate 3-kinase activity

PPIP5K1 PPIP5K2

7.87e-054732GO:0052724
GeneOntologyMolecularFunctioninositol hexakisphosphate 1-kinase activity

PPIP5K1 PPIP5K2

7.87e-054732GO:0052723
GeneOntologyMolecularFunctionryanodine-sensitive calcium-release channel activity

RYR1 RYR3

7.87e-054732GO:0005219
GeneOntologyMolecularFunctionglutaminase activity

NADSYN1 GLS2

7.87e-054732GO:0004359
GeneOntologyMolecularFunctiontransmembrane transporter activity

SCN11A ABCA2 ATP8A1 SCN1A SCN2A SCN3A SCN5A SCN8A SCN9A KCNIP1 RYR1 RYR3 GABRA1 ITPR2

8.16e-0511807314GO:0022857
GeneOntologyMolecularFunctionmicrotubule motor activity

KIF21B DNAL4 DNAH9 DNAH1

1.26e-0470734GO:0003777
GeneOntologyMolecularFunctioninositol hexakisphosphate 5-kinase activity

PPIP5K1 PPIP5K2

1.31e-045732GO:0000832
GeneOntologyMolecularFunctiondiphosphoinositol pentakisphosphate kinase activity

PPIP5K1 PPIP5K2

1.31e-045732GO:0000829
GeneOntologyMolecularFunctioninositol hexakisphosphate kinase activity

PPIP5K1 PPIP5K2

1.31e-045732GO:0000828
GeneOntologyMolecularFunctioninositol-1,3,4,5,6-pentakisphosphate kinase activity

PPIP5K1 PPIP5K2

1.31e-045732GO:0000827
GeneOntologyMolecularFunctionligand-gated calcium channel activity

RYR1 RYR3 ITPR2

1.96e-0431733GO:0099604
GeneOntologyMolecularFunctioncalcium-induced calcium release activity

RYR1 RYR3

1.96e-046732GO:0048763
GeneOntologyMolecularFunctiontransporter activity

SCN11A ABCA2 ATP8A1 SCN1A SCN2A SCN3A SCN5A SCN8A SCN9A KCNIP1 RYR1 RYR3 GABRA1 ITPR2

2.07e-0412897314GO:0005215
GeneOntologyMolecularFunctionintracellularly ligand-gated monoatomic ion channel activity

RYR1 RYR3 ITPR2

2.36e-0433733GO:0005217
GeneOntologyMolecularFunctioninositol phosphate kinase activity

PPIP5K1 PPIP5K2

7.10e-0411732GO:0180030
GeneOntologyMolecularFunctioncytoskeletal motor activity

KIF21B DNAL4 DNAH9 DNAH1

9.21e-04118734GO:0003774
GeneOntologyMolecularFunctiongated channel activity

SCN1A SCN2A RYR1 RYR3 GABRA1 ITPR2

1.39e-03334736GO:0022836
GeneOntologyMolecularFunctionfloppase activity

ABCA2 ATP8A1

1.53e-0316732GO:0140328
GeneOntologyMolecularFunctioncalmodulin binding

SCN2A SCN3A SCN5A RYR1 RYR3

1.54e-03230735GO:0005516
GeneOntologyMolecularFunctionvoltage-gated monoatomic ion channel activity involved in regulation of presynaptic membrane potential

SCN1A SCN2A

1.73e-0317732GO:0099508
GeneOntologyMolecularFunctionATP-dependent activity

ACSL1 KIF21B DNAL4 ABCA2 ATP8A1 MCM2 DNAH9 DNAH1

1.77e-03614738GO:0140657
GeneOntologyMolecularFunctionminus-end-directed microtubule motor activity

DNAH9 DNAH1

1.94e-0318732GO:0008569
GeneOntologyMolecularFunctionadenylate cyclase activity

GUCY2F ADCY9

1.94e-0318732GO:0004016
GeneOntologyMolecularFunctionhydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides

NADSYN1 GLS2 FAAH

3.26e-0381733GO:0016811
GeneOntologyMolecularFunctioncyclase activity

GUCY2F ADCY9

3.45e-0324732GO:0009975
GeneOntologyMolecularFunctionphosphorus-oxygen lyase activity

GUCY2F ADCY9

3.75e-0325732GO:0016849
GeneOntologyMolecularFunctiondynein light intermediate chain binding

DNAH9 DNAH1

4.69e-0328732GO:0051959
GeneOntologyMolecularFunctionATPase-coupled intramembrane lipid transporter activity

ABCA2 ATP8A1

4.69e-0328732GO:0140326
GeneOntologyMolecularFunctionligand-gated monoatomic ion channel activity

RYR1 RYR3 GABRA1 ITPR2

5.48e-03193734GO:0015276
GeneOntologyMolecularFunctionmethyl-CpG binding

ZBTB38 DNMT1

5.72e-0331732GO:0008327
GeneOntologyMolecularFunctionligand-gated channel activity

RYR1 RYR3 GABRA1 ITPR2

5.89e-03197734GO:0022834
GeneOntologyMolecularFunctionnuclear androgen receptor binding

NCOA3 KDM5D

6.47e-0333732GO:0050681
GeneOntologyMolecularFunctiondynein intermediate chain binding

DNAH9 DNAH1

8.08e-0337732GO:0045505
GeneOntologyBiologicalProcessmembrane depolarization during action potential

SCN11A SCN1A SCN2A SCN3A SCN5A SCN8A SCN9A

4.39e-1136747GO:0086010
GeneOntologyBiologicalProcesscardiac muscle cell action potential involved in contraction

SCN11A SCN1A SCN2A SCN3A SCN5A SCN8A CTNNA3 SCN9A

5.38e-1162748GO:0086002
GeneOntologyBiologicalProcesscardiac muscle cell action potential

SCN11A SCN1A SCN2A SCN3A SCN5A SCN8A CTNNA3 SCN9A

8.67e-1087748GO:0086001
GeneOntologyBiologicalProcesscardiac muscle cell contraction

SCN11A SCN1A SCN2A SCN3A SCN5A SCN8A CTNNA3 SCN9A

1.48e-0993748GO:0086003
GeneOntologyBiologicalProcessneuronal action potential

SCN11A SCN1A SCN2A SCN3A SCN5A SCN8A SCN9A

2.70e-0963747GO:0019228
GeneOntologyBiologicalProcessstriated muscle contraction

SCN11A SCN1A SCN2A SCN3A SCN5A SCN8A CTNNA3 SCN9A RYR1 RYR3

5.39e-092177410GO:0006941
GeneOntologyBiologicalProcessactin-mediated cell contraction

SCN11A SCN1A SCN2A SCN3A SCN5A SCN8A CTNNA3 SCN9A

1.77e-08127748GO:0070252
GeneOntologyBiologicalProcessaction potential

SCN11A SCN1A SCN2A SCN3A SCN5A SCN8A CTNNA3 SCN9A KCNIP1

4.24e-08201749GO:0001508
GeneOntologyBiologicalProcessactin filament-based movement

SCN11A SCN1A SCN2A SCN3A SCN5A SCN8A CTNNA3 SCN9A

7.60e-08153748GO:0030048
GeneOntologyBiologicalProcesscardiac muscle contraction

SCN11A SCN1A SCN2A SCN3A SCN5A SCN8A CTNNA3 SCN9A

1.49e-07167748GO:0060048
GeneOntologyBiologicalProcesstransmission of nerve impulse

SCN11A SCN1A SCN2A SCN3A SCN5A SCN8A SCN9A

1.54e-07112747GO:0019226
GeneOntologyBiologicalProcessmembrane depolarization

SCN11A SCN1A SCN2A SCN3A SCN5A SCN8A SCN9A

2.61e-07121747GO:0051899
GeneOntologyBiologicalProcessregulation of membrane potential

SCN11A SCN1A SCN2A SCN3A SCN5A SCN8A CTNNA3 SCN9A CKAP5 KCNIP1 OPRD1 GABRA1

6.63e-075597412GO:0042391
GeneOntologyBiologicalProcessmuscle contraction

SCN11A SCN1A SCN2A SCN3A SCN5A SCN8A CTNNA3 SCN9A RYR1 RYR3

1.60e-064007410GO:0006936
GeneOntologyBiologicalProcesssodium ion transmembrane transport

SCN11A SCN1A SCN2A SCN3A SCN5A SCN8A SCN9A

9.74e-06208747GO:0035725
GeneOntologyBiologicalProcesscirculatory system process

SCN11A ABCA2 ATP8A1 AVPR2 SCN1A SCN2A SCN3A SCN5A SCN8A CTNNA3 SCN9A FAAH

1.08e-057337412GO:0003013
GeneOntologyBiologicalProcessheart contraction

SCN11A SCN1A SCN2A SCN3A SCN5A SCN8A CTNNA3 SCN9A

1.14e-05298748GO:0060047
GeneOntologyBiologicalProcessheart process

SCN11A SCN1A SCN2A SCN3A SCN5A SCN8A CTNNA3 SCN9A

1.48e-05309748GO:0003015
GeneOntologyBiologicalProcessorganophosphate biosynthetic process

ACSL1 ABCA2 NADSYN1 GUCY2F PIGK PDHB UCKL1 PPIP5K1 PPIP5K2 ADCY9 MVD

1.77e-056447411GO:0090407
GeneOntologyBiologicalProcessmuscle system process

SCN11A SCN1A SCN2A SCN3A SCN5A SCN8A CTNNA3 SCN9A RYR1 RYR3

2.48e-055477410GO:0003012
GeneOntologyBiologicalProcesssodium ion transport

SCN11A SCN1A SCN2A SCN3A SCN5A SCN8A SCN9A

5.83e-05275747GO:0006814
GeneOntologyBiologicalProcessblood circulation

SCN11A AVPR2 SCN1A SCN2A SCN3A SCN5A SCN8A CTNNA3 SCN9A FAAH

1.03e-046487410GO:0008015
GeneOntologyBiologicalProcessmonoatomic cation transmembrane transport

SCN11A ATP8A1 SCN1A SCN2A SCN3A SCN5A SCN8A SCN9A KCNIP1 RYR1 RYR3 ITPR2

1.23e-049427412GO:0098655
GeneOntologyBiologicalProcessbehavioral response to chemical pain

SCN11A SCN9A

1.26e-045742GO:0061366
GeneOntologyBiologicalProcessbehavioral response to formalin induced pain

SCN11A SCN9A

1.26e-045742GO:0061368
GeneOntologyBiologicalProcessmonoatomic ion transmembrane transport

SCN11A ATP8A1 SCN1A SCN2A SCN3A SCN5A SCN8A SCN9A KCNIP1 RYR1 RYR3 GABRA1 ITPR2

1.51e-0411157413GO:0034220
GeneOntologyBiologicalProcessbehavioral response to pain

SCN11A SCN3A SCN9A

2.04e-0432743GO:0048266
GeneOntologyBiologicalProcessregulation of action potential

SCN5A CTNNA3 SCN9A KCNIP1

2.06e-0481744GO:0098900
GeneOntologyBiologicalProcessmetal ion transport

SCN11A SCN1A SCN2A SCN3A SCN5A SCN8A SCN9A KCNIP1 RYR1 RYR3 OPRD1 ITPR2

2.15e-0410007412GO:0030001
GeneOntologyBiologicalProcessmonoatomic cation transport

SCN11A ATP8A1 SCN1A SCN2A SCN3A SCN5A SCN8A SCN9A KCNIP1 RYR1 RYR3 OPRD1 ITPR2

2.18e-0411577413GO:0006812
GeneOntologyBiologicalProcessinorganic ion transmembrane transport

SCN11A SCN1A SCN2A SCN3A SCN5A SCN8A SCN9A KCNIP1 RYR1 RYR3 GABRA1 ITPR2

2.51e-0410177412GO:0098660
GeneOntologyBiologicalProcessbehavior

SCN11A ABCA2 ATP8A1 SCN1A SCN2A SCN3A SCN8A SCN9A CKAP5 DMBX1 OPRD1

3.18e-048917411GO:0007610
GeneOntologyBiologicalProcessmonoatomic ion transport

SCN11A ATP8A1 SCN1A SCN2A SCN3A SCN5A SCN8A SCN9A KCNIP1 RYR1 RYR3 OPRD1 GABRA1 ITPR2

3.32e-0413747414GO:0006811
GeneOntologyBiologicalProcessinorganic cation transmembrane transport

SCN11A SCN1A SCN2A SCN3A SCN5A SCN8A SCN9A KCNIP1 RYR1 RYR3 ITPR2

4.25e-049227411GO:0098662
GeneOntologyBiologicalProcesscentral nervous system myelin formation

ABCA2 CKAP5

4.50e-049742GO:0032289
GeneOntologyBiologicalProcessdetection of stimulus involved in sensory perception of pain

SCN11A SCN1A SCN9A

4.93e-0443743GO:0062149
GeneOntologyBiologicalProcesslocomotory behavior

ABCA2 SCN1A SCN8A CKAP5 DMBX1 OPRD1

5.47e-04284746GO:0007626
GeneOntologyBiologicalProcessinositol metabolic process

PPIP5K1 PPIP5K2

5.61e-0410742GO:0006020
GeneOntologyBiologicalProcesscellular response to caffeine

RYR1 RYR3

6.84e-0411742GO:0071313
GeneOntologyBiologicalProcessorganophosphate metabolic process

ACSL1 MTMR12 ABCA2 NADSYN1 GUCY2F PIGK PDHB UCKL1 PPIP5K1 PPIP5K2 ADCY9 MVD

7.12e-0411427412GO:0019637
GeneOntologyBiologicalProcessadult locomotory behavior

SCN1A SCN8A DMBX1 OPRD1

8.07e-04116744GO:0008344
GeneOntologyBiologicalProcessresponse to pain

SCN11A SCN3A SCN9A

8.16e-0451743GO:0048265
GeneOntologyBiologicalProcessnucleotide biosynthetic process

ACSL1 NADSYN1 GUCY2F PDHB UCKL1 ADCY9

1.00e-03319746GO:0009165
GeneOntologyBiologicalProcessnucleoside phosphate biosynthetic process

ACSL1 NADSYN1 GUCY2F PDHB UCKL1 ADCY9

1.02e-03320746GO:1901293
GeneOntologyBiologicalProcesscellular response to purine-containing compound

RYR1 RYR3

1.12e-0314742GO:0071415
GeneOntologyBiologicalProcessdetection of mechanical stimulus involved in sensory perception

SCN11A SCN1A SCN9A

1.13e-0357743GO:0050974
GeneOntologyBiologicalProcessresponse to organic cyclic compound

ACSL1 NCOA3 SCN5A ALAS1 KDM5D RYR1 RYR3 OPRD1 DNMT1 GABRA1 ITPR2

1.22e-0310487411GO:0014070
GeneOntologyBiologicalProcessbundle of His cell to Purkinje myocyte communication

SCN5A CTNNA3

1.29e-0315742GO:0086069
GeneOntologyCellularComponentvoltage-gated sodium channel complex

SCN11A SCN1A SCN2A SCN3A SCN5A SCN8A SCN9A

1.19e-1317767GO:0001518
GeneOntologyCellularComponentsodium channel complex

SCN11A SCN1A SCN2A SCN3A SCN5A SCN8A SCN9A

9.26e-1229767GO:0034706
GeneOntologyCellularComponenttransporter complex

SHISA9 SCN11A ABCA2 ATP8A1 SCN1A SCN2A SCN3A SCN5A SCN8A SCN9A KCNIP1 RYR1 RYR3 GABRA1

9.94e-095507614GO:1990351
GeneOntologyCellularComponentmonoatomic ion channel complex

SHISA9 SCN11A SCN1A SCN2A SCN3A SCN5A SCN8A SCN9A KCNIP1 RYR1 RYR3 GABRA1

1.13e-083787612GO:0034702
GeneOntologyCellularComponentcation channel complex

SCN11A SCN1A SCN2A SCN3A SCN5A SCN8A SCN9A KCNIP1 RYR1 RYR3

1.33e-082357610GO:0034703
GeneOntologyCellularComponenttransmembrane transporter complex

SHISA9 SCN11A ABCA2 SCN1A SCN2A SCN3A SCN5A SCN8A SCN9A KCNIP1 RYR1 RYR3 GABRA1

4.70e-085237613GO:1902495
GeneOntologyCellularComponentplasma membrane protein complex

SHISA9 SCN11A ABCA2 SCN1A SCN2A SCN3A SCN5A SCN8A SCN9A C8B KCNIP1 RYR1

2.47e-057857612GO:0098797
GeneOntologyCellularComponentnode of Ranvier

SCN1A SCN2A SCN8A

5.04e-0520763GO:0033268
GeneOntologyCellularComponentsarcoplasm

MTMR12 SCN3A RYR1 RYR3 ITPR2

5.99e-05114765GO:0016528
GeneOntologyCellularComponentintercalated disc

SCN1A SCN2A SCN5A CTNNA3

1.10e-0468764GO:0014704
GeneOntologyCellularComponentaxon initial segment

SCN1A SCN2A SCN8A

1.58e-0429763GO:0043194
GeneOntologyCellularComponentglutamatergic synapse

DOCK1 SHISA9 KIF21B SCN11A ATP8A1 TRIO DROSHA SCN2A SCN8A ARFGEF2 FAAH

1.71e-048177611GO:0098978
GeneOntologyCellularComponentT-tubule

SCN1A SCN2A SCN5A RYR1

1.97e-0479764GO:0030315
GeneOntologyCellularComponentZ disc

SCN1A SCN5A SCN8A RYR1 RYR3

2.25e-04151765GO:0030018
GeneOntologyCellularComponentmembrane protein complex

SHISA9 SCN11A ABCA2 PIGK SCN1A SCN2A SCN3A SCN5A SCN8A SCN9A C8B KCNIP1 RYR1 RYR3 GABRA1

2.79e-0414987615GO:0098796
GeneOntologyCellularComponentsarcomere

MTMR12 SCN1A SCN5A SCN8A RYR1 RYR3

2.93e-04249766GO:0030017
GeneOntologyCellularComponentsarcoplasmic reticulum

MTMR12 RYR1 RYR3 ITPR2

2.99e-0488764GO:0016529
GeneOntologyCellularComponentI band

SCN1A SCN5A SCN8A RYR1 RYR3

3.49e-04166765GO:0031674
GeneOntologyCellularComponentaxon

KIF21B SCN11A SCN1A SCN2A SCN3A SCN5A SCN8A SCN9A ADCY9 OPRD1 ITPR2

3.60e-048917611GO:0030424
GeneOntologyCellularComponentcell-cell contact zone

SCN1A SCN2A SCN5A CTNNA3

3.84e-0494764GO:0044291
GeneOntologyCellularComponentjunctional membrane complex

RYR1 RYR3

4.62e-049762GO:0030314
GeneOntologyCellularComponentmyofibril

MTMR12 SCN1A SCN5A SCN8A RYR1 RYR3

4.78e-04273766GO:0030016
GeneOntologyCellularComponentsarcoplasmic reticulum membrane

RYR1 RYR3 ITPR2

5.87e-0445763GO:0033017
GeneOntologyCellularComponentsarcolemma

SCN1A SCN2A SCN5A RYR1 RYR3

6.45e-04190765GO:0042383
GeneOntologyCellularComponentcontractile muscle fiber

MTMR12 SCN1A SCN5A SCN8A RYR1 RYR3

6.56e-04290766GO:0043292
GeneOntologyCellularComponentdynein complex

DNAL4 DNAH9 DNAH1

1.00e-0354763GO:0030286
GeneOntologyCellularComponentsupramolecular fiber

KIF21B DNAL4 MTMR12 SCN1A SCN5A SCN8A CKAP5 ARFGEF2 DNAH9 RYR1 RYR3 DNAH1

1.07e-0311797612GO:0099512
GeneOntologyCellularComponentdendrite membrane

SHISA9 OPRD1 GABRA1

1.11e-0356763GO:0032590
GeneOntologyCellularComponentsupramolecular polymer

KIF21B DNAL4 MTMR12 SCN1A SCN5A SCN8A CKAP5 ARFGEF2 DNAH9 RYR1 RYR3 DNAH1

1.13e-0311877612GO:0099081
GeneOntologyCellularComponentsomatodendritic compartment

SHISA9 KIF21B SCN11A SCN1A SCN3A SCN8A CKAP5 ARFGEF2 KCNIP1 ADCY9 OPRD1 GABRA1

1.51e-0312287612GO:0036477
GeneOntologyCellularComponentmicrotubule associated complex

KIF21B DNAL4 DNAH9 DNAH1

2.83e-03161764GO:0005875
GeneOntologyCellularComponentneuron projection membrane

SHISA9 OPRD1 GABRA1

3.33e-0382763GO:0032589
GeneOntologyCellularComponentpresynaptic membrane

SCN11A SCN1A SCN2A SCN8A OPRD1

3.38e-03277765GO:0042734
GeneOntologyCellularComponentaxonemal dynein complex

DNAH9 DNAH1

3.71e-0325762GO:0005858
GeneOntologyCellularComponentdendrite

SHISA9 KIF21B SCN8A CKAP5 ARFGEF2 KCNIP1 ADCY9 OPRD1 GABRA1

3.85e-03858769GO:0030425
GeneOntologyCellularComponentdendritic tree

SHISA9 KIF21B SCN8A CKAP5 ARFGEF2 KCNIP1 ADCY9 OPRD1 GABRA1

3.91e-03860769GO:0097447
GeneOntologyCellularComponentmain axon

SCN1A SCN2A SCN8A

4.19e-0389763GO:0044304
GeneOntologyCellularComponentsynaptic membrane

SHISA9 SCN11A SCN1A SCN2A SCN8A OPRD1 GABRA1

5.26e-03583767GO:0097060
GeneOntologyCellularComponentpostsynaptic specialization membrane

SHISA9 SCN8A OPRD1 GABRA1

6.21e-03201764GO:0099634
HumanPhenoDysgenesis of the hippocampus

DNAL4 SCN1A SCN2A SCN9A GABRA1

4.71e-0816355HP:0025101
HumanPhenoComplex febrile seizure

SCN1A SCN2A SCN8A SCN9A GABRA1

4.71e-0816355HP:0011172
HumanPhenoPhotosensitive myoclonic seizure

SCN1A SCN2A SCN9A GABRA1

1.28e-078354HP:0001327
HumanPhenoCyanotic episode

SCN1A SCN2A SCN9A GABRA1

1.28e-078354HP:0200048
HumanPhenoFocal hemiclonic seizure

SCN1A SCN2A SCN8A SCN9A GABRA1

5.48e-0725355HP:0006813
HumanPhenoLimited neck range of motion

SCN1A SCN2A SCN9A GABRA1

5.96e-0711354HP:0000466
HumanPhenoAbnormal hippocampus morphology

DNAL4 CEP85L SCN1A SCN2A SCN9A GABRA1

6.70e-0748356HP:0025100
HumanPhenoAbnormal morphology of the limbic system

DNAL4 CEP85L SCN1A SCN2A SCN9A GABRA1

7.60e-0749356HP:0007343
HumanPhenoEpilepsia partialis continua

SCN1A SCN2A SCN9A GABRA1

8.89e-0712354HP:0012847
HumanPhenoObsessive-compulsive trait

TRIO SCN1A SCN2A SCN9A GABRA1

2.35e-0633355HP:0008770
HumanPhenoFacial tics

SCN1A SCN2A SCN9A GABRA1

2.42e-0615354HP:0011468
HumanPhenoPhotosensitive tonic-clonic seizure

SCN1A SCN2A SCN9A GABRA1

2.42e-0615354HP:0007207
HumanPhenoGeneralized clonic seizure

SCN1A SCN2A SCN8A SCN9A GABRA1

2.74e-0634355HP:0011169
HumanPhenoFocal motor status epilepticus

SCN1A SCN2A SCN9A GABRA1

4.17e-0617354HP:0032663
HumanPhenoVisually-induced seizure

SCN1A SCN2A SCN9A GABRA1

5.34e-0618354HP:0020216
HumanPhenoPoor fine motor coordination

MKRN3 DNAL4 SCN1A SCN2A SCN9A GABRA1

5.90e-0669356HP:0007010
HumanPhenoFocal clonic seizure

SCN1A SCN2A SCN8A SCN9A GABRA1

8.07e-0642355HP:0002266
HumanPhenoReflex seizure

SCN1A SCN2A SCN9A GABRA1

1.25e-0522354HP:0020207
HumanPhenoAtypical absence seizure

CEP85L SCN1A SCN2A SCN9A GABRA1

1.27e-0546355HP:0007270
HumanPhenoClonic seizure

SCN1A SCN2A SCN3A SCN8A SCN9A GABRA1

1.51e-0581356HP:0020221
HumanPhenoTibial torsion

SCN1A SCN2A SCN9A GABRA1

1.51e-0523354HP:0100694
HumanPhenoFocal impaired awareness seizure

CEP85L SCN1A SCN2A SCN3A SCN8A SCN9A GABRA1

1.81e-05126357HP:0002384
HumanPhenoAggressive behavior

MKRN3 ABCA2 TRIO CEP85L RBL2 SCN1A SCN2A SCN3A SCN8A SCN9A TRAPPC10 DNMT1 GABRA1

1.84e-055163513HP:0000718
HumanPhenoAbnormal aggressive, impulsive or violent behavior

MKRN3 ABCA2 TRIO CEP85L RBL2 SCN1A SCN2A SCN3A SCN8A SCN9A TRAPPC10 DNMT1 GABRA1

1.84e-055163513HP:0006919
HumanPhenoPoor motor coordination

MKRN3 DNAL4 SCN1A SCN2A SCN9A GABRA1

1.99e-0585356HP:0002275
HumanPhenoLimited knee extension

SCN1A SCN2A SCN9A GABRA1

2.93e-0527354HP:0003066
HumanPhenoStatus epilepticus without prominent motor symptoms

SCN1A SCN2A SCN9A GABRA1

2.93e-0527354HP:0031475
HumanPhenoSimple febrile seizure

SCN1A SCN2A SCN3A SCN8A

2.93e-0527354HP:0011171
HumanPhenoFocal aware seizure

SCN1A SCN2A SCN9A GABRA1

3.40e-0528354HP:0002349
HumanPhenoStatus epilepticus with prominent motor symptoms

SCN1A SCN2A SCN9A GABRA1

3.93e-0529354HP:0032658
HumanPhenoProgressive gait ataxia

SCN1A SCN2A SCN9A GABRA1

4.51e-0530354HP:0007240
HumanPhenoProgressive ataxia

SCN1A SCN2A SCN9A GABRA1

4.51e-0530354HP:0001329
HumanPhenoInfection-related seizure

CEP85L SCN1A SCN2A SCN3A SCN8A SCN9A GABRA1

4.51e-05145357HP:0032892
HumanPhenoSeizure precipitated by febrile infection

CEP85L SCN1A SCN2A SCN3A SCN8A SCN9A GABRA1

4.51e-05145357HP:0032894
HumanPhenoFebrile seizure (within the age range of 3 months to 6 years)

CEP85L SCN1A SCN2A SCN3A SCN8A SCN9A GABRA1

4.51e-05145357HP:0002373
HumanPhenoImpulsivity

SCN1A SCN2A SCN3A SCN8A SCN9A DNMT1 GABRA1

5.38e-05149357HP:0100710
HumanPhenoCogwheel rigidity

SCN1A SCN2A SCN9A GABRA1

5.86e-0532354HP:0002396
HumanPhenoFocal automatism seizure

SCN1A SCN2A SCN8A

6.27e-0512353HP:0032898
HumanPhenoGeneralized tonic seizure

SCN1A SCN2A SCN8A SCN9A GABRA1

6.49e-0564355HP:0010818
HumanPhenoMultifocal epileptiform discharges

SCN1A SCN2A SCN8A SCN9A GABRA1

7.53e-0566355HP:0010841
HumanPhenoGeneralized cerebral atrophy/hypoplasia

SCN1A SCN2A SCN9A

8.11e-0513353HP:0007058
HumanPhenoLimitation of knee mobility

SCN1A SCN2A SCN9A GABRA1

8.41e-0535354HP:0010501
HumanPhenoLimitation of neck motion

SCN1A SCN2A SCN9A GABRA1

9.41e-0536354HP:0005986
HumanPhenoAbnormal neck physiology

SCN1A SCN2A SCN9A GABRA1

9.41e-0536354HP:0025669
HumanPhenoDisturbance of facial expression

SCN1A SCN2A SCN9A GABRA1

9.41e-0536354HP:0005324
HumanPhenoAtypical absence status epilepticus

SCN1A SCN2A SCN9A

1.89e-0417353HP:0011151
HumanPhenoGeneralized non-convulsive status epilepticus without coma

SCN1A SCN2A SCN9A

2.26e-0418353HP:0032860
HumanPhenoFocal motor seizure

CEP85L SCN1A SCN2A SCN8A SCN9A GABRA1

2.27e-04131356HP:0011153
HumanPhenoAbnormal knee physiology

SCN1A SCN2A SCN9A RYR1 GABRA1

2.81e-0487355HP:0034670
HumanPhenoEEG with spike-wave complexes

SCN1A SCN2A SCN8A SCN9A GABRA1

2.96e-0488355HP:0010850
HumanPhenoNon-convulsive status epilepticus without coma

SCN1A SCN2A SCN9A

3.13e-0420353HP:0032671
HumanPhenoTonic seizure

CEP85L SCN1A SCN2A SCN8A SCN9A GABRA1

3.26e-04140356HP:0032792
HumanPhenoTalipes valgus

SCN1A SCN2A SCN9A

3.63e-0421353HP:0004684
HumanPhenoBilateral tonic-clonic seizure with focal onset

CEP85L SCN1A SCN2A SCN8A

4.00e-0452354HP:0007334
HumanPhenoBilateral tonic-clonic seizure with generalized onset

SCN1A SCN2A SCN9A GABRA1

4.00e-0452354HP:0025190
HumanPhenoAtonic seizure

CEP85L SCN1A SCN2A SCN9A GABRA1

4.03e-0494355HP:0010819
HumanPhenoNeonatal electro-clinical non-motor seizure

SCN2A SCN8A

4.53e-045352HP:0032812
HumanPhenoNeonatal seizure with electrographic correlate

SCN2A SCN8A

4.53e-045352HP:0032808
HumanPhenoNeonatal electro-clinical seizure

SCN2A SCN8A

4.53e-045352HP:0032809
HumanPhenoNeonatal electro-clinical seizure with behavior arrest

SCN2A SCN8A

4.53e-045352HP:0032823
HumanPhenoFocal head nodding automatism seizure

SCN2A SCN8A

4.53e-045352HP:0032906
HumanPhenoAllodynia

SCN11A SCN9A

4.53e-045352HP:0012533
HumanPhenoRigidity

SCN1A SCN2A SCN3A SCN8A SCN9A RYR1 GABRA1

5.15e-04214357HP:0002063
HumanPhenoPes valgus

SCN1A SCN2A SCN9A GABRA1

5.33e-0456354HP:0008081
HumanPhenoIntellectual disability, borderline

TRIO SCN3A SCN8A

6.16e-0425353HP:0006889
HumanPhenoCompulsive behaviors

TRIO SCN1A SCN2A SCN8A SCN9A GABRA1

6.23e-04158356HP:0000722
HumanPhenoNormal interictal EEG

SCN2A SCN8A

6.76e-046352HP:0002372
HumanPhenoAbnormality of pain sensation

MKRN3 SCN11A TRIO SCN1A SCN9A

9.38e-04113355HP:0010832
HumanPhenoEyelid myoclonia seizure

SCN2A SCN8A

9.43e-047352HP:0032678
HumanPhenoPain insensitivity

SCN11A TRIO SCN9A

9.61e-0429353HP:0007021
HumanPhenoLimb myoclonus

SCN2A SCN8A GABRA1

9.61e-0429353HP:0045084
HumanPhenoCyanosis

SCN1A SCN2A SCN8A SCN9A GABRA1

1.10e-03117355HP:0000961
HumanPhenoGeneralized non-motor (absence) seizure

CEP85L SCN1A SCN2A SCN8A SCN9A GABRA1

1.10e-03176356HP:0002121
HumanPhenoEEG with focal epileptiform discharges

SCN1A SCN2A SCN8A SCN9A GABRA1

1.14e-03118355HP:0011185
HumanPhenoEpileptic encephalopathy

SCN1A SCN2A SCN3A SCN8A GABRA1

1.18e-03119355HP:0200134
HumanPhenoAbnormal nasal mucus secretion

SCN9A DNAH1

1.25e-038352HP:0031416
HumanPhenoRhinorrhea

SCN9A DNAH1

1.25e-038352HP:0031417
HumanPhenoDialeptic seizure

CEP85L SCN1A SCN2A SCN3A SCN8A SCN9A GABRA1

1.33e-03251357HP:0011146
HumanPhenoCalcaneovalgus deformity

SCN1A SCN2A SCN9A

1.54e-0334353HP:0001848
HumanPhenoAbnormal social development

MKRN3 ABCA2 TRIO CEP85L RBL2 SCN1A SCN2A SCN3A SCN8A SCN9A ARFGEF2 TRAPPC10 DNMT1 GABRA1

1.67e-039083514HP:0025732
HumanPhenoDeformed tarsal bones

SCN1A SCN2A SCN9A

1.67e-0335353HP:0008119
HumanPhenoMyoclonic seizure

CEP85L RBL2 SCN1A SCN2A SCN8A SCN9A GABRA1

1.71e-03262357HP:0032794
HumanPhenoGait ataxia

ABCA2 TRIO SCN1A SCN2A SCN8A SCN9A GABRA1

1.75e-03263357HP:0002066
HumanPhenoDisinhibition

MKRN3 ABCA2 TRIO CEP85L RBL2 SCN1A SCN2A SCN3A SCN8A SCN9A TRAPPC10 DNMT1 GABRA1

1.77e-038073513HP:0000734
HumanPhenoInappropriate behavior

MKRN3 ABCA2 TRIO CEP85L RBL2 SCN1A SCN2A SCN3A SCN8A SCN9A TRAPPC10 DNMT1 GABRA1

1.77e-038073513HP:0000719
HumanPhenoAbnormal response to social norms

MKRN3 ABCA2 TRIO CEP85L RBL2 SCN1A SCN2A SCN3A SCN8A SCN9A TRAPPC10 DNMT1 GABRA1

1.77e-038073513HP:5200123
HumanPhenoSocial disinhibition

MKRN3 ABCA2 TRIO CEP85L RBL2 SCN1A SCN2A SCN3A SCN8A SCN9A TRAPPC10 DNMT1 GABRA1

1.77e-038073513HP:5200029
HumanPhenoFocal-onset seizure

CEP85L SCN1A SCN2A SCN3A SCN8A SCN9A ARFGEF2 GABRA1

1.94e-03346358HP:0007359
HumanPhenoNon-motor seizure

CEP85L SCN1A SCN2A SCN8A SCN9A GABRA1

1.97e-03197356HP:0033259
HumanPhenoSudden unexpected death in epilepsy

SCN1A SCN8A

1.99e-0310352HP:0033258
HumanPhenoErythromelalgia

SCN11A SCN9A

1.99e-0310352HP:0032147
HumanPhenoDelirium

RYR1 DNMT1

1.99e-0310352HP:0031258
HumanPhenoEEG with generalized epileptiform discharges

SCN1A SCN2A SCN3A SCN8A SCN9A ARFGEF2 GABRA1

2.03e-03270357HP:0011198
HumanPhenoNeonatal seizure

SCN2A SCN8A

2.43e-0311352HP:0032807
HumanPhenoImpaired pain sensation

MKRN3 SCN11A TRIO SCN9A

2.44e-0384354HP:0007328
HumanPhenoFocal non-motor seizure

SCN1A SCN2A SCN8A

2.47e-0340353HP:0032679
HumanPhenoStatus epilepticus

SCN1A SCN2A SCN3A SCN8A SCN9A GABRA1

2.53e-03207356HP:0002133
MousePhenoabnormal action potential

SHISA9 SCN11A SCN1A SCN2A SCN5A SCN8A SCN9A

2.14e-06133637MP:0005402
MousePhenoabnormal nervous system electrophysiology

EBF2 SHISA9 SCN11A SCN1A SCN2A SCN5A SCN8A SCN9A CHN1

1.54e-05329639MP:0002272
DomainNa_channel_asu

SCN11A SCN1A SCN2A SCN3A SCN5A SCN8A SCN9A

1.50e-1510757IPR001696
DomainNa_trans_assoc

SCN11A SCN1A SCN2A SCN3A SCN5A SCN8A SCN9A

1.50e-1510757IPR010526
DomainNa_trans_assoc

SCN11A SCN1A SCN2A SCN3A SCN5A SCN8A SCN9A

1.50e-1510757PF06512
DomainNa_trans_cytopl

SCN1A SCN2A SCN3A SCN5A SCN8A SCN9A

3.42e-156756PF11933
DomainNa_trans_cytopl

SCN1A SCN2A SCN3A SCN5A SCN8A SCN9A

3.42e-156756IPR024583
DomainIon_trans_dom

SCN11A SCN1A SCN2A SCN3A SCN5A SCN8A SCN9A RYR1 RYR3 ITPR2

2.86e-111147510IPR005821
DomainIon_trans

SCN11A SCN1A SCN2A SCN3A SCN5A SCN8A SCN9A RYR1 RYR3 ITPR2

2.86e-111147510PF00520
DomainChannel_four-helix_dom

SCN11A SCN1A SCN2A SCN3A SCN5A SCN8A SCN9A

2.85e-0957757IPR027359
Domain-

SCN11A SCN1A SCN2A SCN3A SCN5A SCN8A SCN9A

2.85e-09577571.20.120.350
DomainIQ

SCN1A SCN2A SCN3A SCN5A SCN8A SCN9A

8.75e-0781756SM00015
DomainRIH_assoc

RYR1 RYR3 ITPR2

1.23e-066753PF08454
DomainRIH_assoc-dom

RYR1 RYR3 ITPR2

1.23e-066753IPR013662
DomainRIH_dom

RYR1 RYR3 ITPR2

1.23e-066753IPR000699
DomainIns145_P3_rcpt

RYR1 RYR3 ITPR2

1.23e-066753IPR014821
DomainRyanodine_recept-rel

RYR1 RYR3 ITPR2

1.23e-066753IPR015925
Domain-

RYR1 RYR3 ITPR2

1.23e-0667531.25.10.30
DomainRYDR_ITPR

RYR1 RYR3 ITPR2

1.23e-066753PF01365
DomainIns145_P3_rec

RYR1 RYR3 ITPR2

1.23e-066753PF08709
DomainIQ_motif_EF-hand-BS

SCN1A SCN2A SCN3A SCN5A SCN8A SCN9A

1.63e-0690756IPR000048
DomainIQ

SCN1A SCN2A SCN3A SCN5A SCN8A SCN9A

1.98e-0693756PS50096
DomainMIR

RYR1 RYR3 ITPR2

7.31e-0610753PS50919
DomainMIR

RYR1 RYR3 ITPR2

7.31e-0610753PF02815
DomainMIR

RYR1 RYR3 ITPR2

7.31e-0610753SM00472
DomainMIR_motif

RYR1 RYR3 ITPR2

7.31e-0610753IPR016093
DomainEF-hand-dom_pair

SCN1A SCN3A SCN8A SCN9A GCA KCNIP1 RYR1 RYR3

1.95e-05287758IPR011992
DomainRyanrecept_TM4-6

RYR1 RYR3

4.76e-053752IPR009460
DomainRyR

RYR1 RYR3

4.76e-053752PF02026
DomainRyanodine_rcpt

RYR1 RYR3

4.76e-053752IPR003032
DomainRR_TM4-6

RYR1 RYR3

4.76e-053752PF06459
DomainRyan_recept

RYR1 RYR3

4.76e-053752IPR013333
DomainARM-type_fold

DOCK1 CKAP5 ARFGEF2 MEI1 WDFY4 VIRMA RYR3 ITPR2

6.35e-05339758IPR016024
DomainIQ

SCN1A SCN3A SCN8A SCN9A

1.90e-0471754PF00612
DomainAcid_Pase_AS

PPIP5K1 PPIP5K2

2.36e-046752IPR033379
DomainHIS_ACID_PHOSPHAT_2

PPIP5K1 PPIP5K2

3.30e-047752PS00778
DomainHIS_ACID_PHOSPHAT_1

PPIP5K1 PPIP5K2

3.30e-047752PS00616
DomainEF-hand_8

GCA KCNIP1 RYR1

3.40e-0434753PF13833
DomainHis_Pase_clade-2

PPIP5K1 PPIP5K2

4.39e-048752IPR000560
DomainHis_Phos_2

PPIP5K1 PPIP5K2

4.39e-048752PF00328
DomainDynein_heavy_chain_D4_dom

DNAH9 DNAH1

1.40e-0314752IPR024317
DomainDynein_HC_stalk

DNAH9 DNAH1

1.40e-0314752IPR024743
DomainDynein_heavy_dom-2

DNAH9 DNAH1

1.40e-0314752IPR013602
DomainDHC_N2

DNAH9 DNAH1

1.40e-0314752PF08393
DomainMT

DNAH9 DNAH1

1.40e-0314752PF12777
DomainAAA_8

DNAH9 DNAH1

1.40e-0314752PF12780
DomainATPase_dyneun-rel_AAA

DNAH9 DNAH1

1.40e-0314752IPR011704
DomainAAA_5

DNAH9 DNAH1

1.40e-0314752PF07728
DomainDHC_fam

DNAH9 DNAH1

1.62e-0315752IPR026983
DomainDynein_heavy_dom

DNAH9 DNAH1

1.62e-0315752IPR004273
DomainDynein_heavy

DNAH9 DNAH1

1.62e-0315752PF03028
DomainA/G_cyclase_CS

GUCY2F ADCY9

2.08e-0317752IPR018297
DomainNucleotide_cyclase

GUCY2F ADCY9

2.34e-0318752IPR029787
Domain-

GUCY2F ADCY9

2.34e-03187523.30.70.1230
DomainGUANYLATE_CYCLASE_1

GUCY2F ADCY9

2.60e-0319752PS00452
DomainGuanylate_cyc

GUCY2F ADCY9

2.60e-0319752PF00211
DomainGUANYLATE_CYCLASE_2

GUCY2F ADCY9

2.60e-0319752PS50125
DomainA/G_cyclase

GUCY2F ADCY9

2.60e-0319752IPR001054
DomainCYCc

GUCY2F ADCY9

2.60e-0319752SM00044
DomainHis_PPase_superfam

PPIP5K1 PPIP5K2

2.88e-0320752IPR029033
Domain-

PPIP5K1 PPIP5K2

2.88e-03207523.40.50.1240
PathwayREACTOME_CARDIAC_CONDUCTION

SCN11A SCN1A SCN2A SCN3A SCN5A SCN8A SCN9A KCNIP1 RYR1 RYR3 ITPR2

2.22e-111306711M27454
PathwayREACTOME_INTERACTION_BETWEEN_L1_AND_ANKYRINS

SCN11A SCN1A SCN2A SCN3A SCN5A SCN8A SCN9A

9.54e-1131677M877
PathwayREACTOME_PHASE_0_RAPID_DEPOLARISATION

SCN11A SCN1A SCN2A SCN3A SCN5A SCN8A SCN9A

1.22e-1032677M27455
PathwayREACTOME_MUSCLE_CONTRACTION

SCN11A SCN1A SCN2A SCN3A SCN5A SCN8A SCN9A KCNIP1 RYR1 RYR3 ITPR2

2.68e-092036711M5485
PathwayWP_ADHD_AND_AUTISM_ASD_PATHWAYS

SCN11A NADSYN1 GLS2 SCN1A SCN2A SCN3A SCN5A SCN8A SCN9A FAAH DNMT1 GABRA1

1.34e-073676712M48346
PathwayREACTOME_L1CAM_INTERACTIONS

SCN11A SCN1A SCN2A SCN3A SCN5A SCN8A SCN9A

1.64e-06121677M872
PathwayWP_DRAVET_SYNDROME

SCN1A SCN2A SCN3A SCN8A

8.76e-0628674M45519
PathwayKEGG_MEDICUS_VARIANT_SCRAPIE_CONFORMATION_PRPSC_TO_MGLUR5_CA2_APOPTOTIC_PATHWAY

RYR1 RYR3 ITPR2

9.42e-0519673M47760
PathwayKEGG_MEDICUS_VARIANT_MUTATION_CAUSED_ABERRANT_SOD1_TO_RETROGRADE_AXONAL_TRANSPORT

DNAL4 DNAH9 DNAH1

2.77e-0427673M47755
Pubmed

International Union of Pharmacology. XLVII. Nomenclature and structure-function relationships of voltage-gated sodium channels.

SCN11A SCN1A SCN2A SCN3A SCN5A SCN8A SCN9A

7.07e-18977716382098
Pubmed

Early development of electrical excitability in the mouse enteric nervous system.

SCN11A SCN3A SCN5A SCN8A SCN9A

4.66e-14577522875929
Pubmed

Regulation of neuronal voltage-gated sodium channels by the ubiquitin-protein ligases Nedd4 and Nedd4-2.

SCN1A SCN2A SCN3A SCN5A SCN8A SCN9A

1.64e-131377615123669
Pubmed

A 'toothache tree' alkylamide inhibits Aδ mechanonociceptors to alleviate mechanical pain.

SCN1A SCN2A SCN3A SCN8A SCN9A

2.79e-13677523652591
Pubmed

Expression pattern of neuronal and skeletal muscle voltage-gated Na+ channels in the developing mouse heart.

SCN1A SCN2A SCN3A SCN5A SCN8A

5.83e-12977515746173
Pubmed

Nav1.1 localizes to axons of parvalbumin-positive inhibitory interneurons: a circuit basis for epileptic seizures in mice carrying an Scn1a gene mutation.

SCN1A SCN2A SCN3A SCN8A

2.22e-11477417537961
Pubmed

Sodium channel expression and transcript variation in the developing brain of human, Rhesus monkey, and mouse.

SCN1A SCN2A SCN3A SCN8A

2.22e-11477435031483
Pubmed

Abnormal changes in voltage-gated sodium channels subtypes NaV1.1, NaV1.2, NaV1.3, NaV1.6 and CaM/CaMKII pathway in low-grade astrocytoma.

SCN1A SCN2A SCN3A SCN8A

2.22e-11477429578003
Pubmed

Nav1.2 haplodeficiency in excitatory neurons causes absence-like seizures in mice.

SCN1A SCN2A SCN3A SCN5A SCN8A

3.65e-111277530175250
Pubmed

A new sodium channel alpha-subunit gene (Scn9a) from Schwann cells maps to the Scn1a, Scn2a, Scn3a cluster of mouse chromosome 2.

SCN1A SCN2A SCN3A SCN9A

1.11e-1057748812438
Pubmed

Structure/function characterization of micro-conotoxin KIIIA, an analgesic, nearly irreversible blocker of mammalian neuronal sodium channels.

SCN2A SCN3A SCN5A SCN8A

1.11e-10577417724025
Pubmed

Voltage-gated sodium channels in taste bud cells.

SCN2A SCN3A SCN9A

1.04e-08377319284629
Pubmed

Sodium channels SCN1A, SCN2A and SCN3A in familial autism.

SCN1A SCN2A SCN3A

1.04e-08377312610651
Pubmed

Mutations in the sodium channel genes SCN1A, SCN3A, and SCN9A in children with epilepsy with febrile seizures plus(EFS+).

SCN1A SCN3A SCN9A

1.04e-08377333895391
Pubmed

SCN1A, SCN2A and SCN3A gene polymorphisms and responsiveness to antiepileptic drugs: a multicenter cohort study and meta-analysis.

SCN1A SCN2A SCN3A

1.04e-08377323859570
Pubmed

Multidrug resistance in epilepsy and polymorphisms in the voltage-gated sodium channel genes SCN1A, SCN2A, and SCN3A: correlation among phenotype, genotype, and mRNA expression.

SCN1A SCN2A SCN3A

1.04e-08377318784617
Pubmed

Characterization of 5' untranslated regions of the voltage-gated sodium channels SCN1A, SCN2A, and SCN3A and identification of cis-conserved noncoding sequences.

SCN1A SCN2A SCN3A

1.04e-08377317544618
Pubmed

Variable patterns of mutation density among NaV1.1, NaV1.2 and NaV1.6 point to channel-specific functional differences associated with childhood epilepsy.

SCN1A SCN2A SCN8A

1.04e-08377332845893
Pubmed

Comparison and optimization of in silico algorithms for predicting the pathogenicity of sodium channel variants in epilepsy.

SCN1A SCN2A SCN8A

1.04e-08377328518218
Pubmed

Reduced sodium current in Purkinje neurons from Nav1.1 mutant mice: implications for ataxia in severe myoclonic epilepsy in infancy.

SCN1A SCN2A SCN8A

1.04e-08377317928448
Pubmed

Early expression of sodium channel transcripts and sodium current by cajal-retzius cells in the preplate of the embryonic mouse neocortex.

SCN1A SCN2A SCN3A

1.04e-08377314973256
Pubmed

Expression of alternatively spliced sodium channel alpha-subunit genes. Unique splicing patterns are observed in dorsal root ganglia.

SCN11A SCN8A SCN9A

1.04e-08377315302875
Pubmed

Large-scale analysis of ion channel gene expression in the mouse heart during perinatal development.

SCN11A SCN1A SCN3A SCN5A SCN8A SCN9A KCNIP1

2.66e-0813977716985003
Pubmed

Neuronal voltage-gated ion channels are genetic modifiers of generalized epilepsy with febrile seizures plus.

SCN1A SCN2A SCN8A

4.17e-08477321156207
Pubmed

Association of sodium voltage-gated channel genes polymorphisms with epilepsy risk and prognosis in the Saudi population.

SCN1A SCN2A SCN3A

4.17e-08477335801810
Pubmed

Use of recombinant inbred strains for studying genetic determinants of responses to alcohol.

SCN1A SCN2A SCN3A

4.17e-0847738974318
Pubmed

Three brain sodium channel alpha-subunit genes are clustered on the proximal segment of mouse chromosome 2.

SCN1A SCN2A SCN3A

1.04e-0757731679748
Pubmed

Case-control association study of polymorphisms in the voltage-gated sodium channel genes SCN1A, SCN2A, SCN3A, SCN1B, and SCN2B and epilepsy.

SCN1A SCN2A SCN3A

1.04e-07577324337656
Pubmed

Chr21 protein-protein interactions: enrichment in proteins involved in intellectual disability, autism, and late-onset Alzheimer's disease.

MKRN3 FRY ABCA2 ZBTB38 TRIO PDHB CEP85L DROSHA RBL2 CKAP5 PPP1R16B ARFGEF2 LDB2 RYR3 DNMT1

1.24e-071285771535914814
Pubmed

Contactin regulates the current density and axonal expression of tetrodotoxin-resistant but not tetrodotoxin-sensitive sodium channels in DRG neurons.

SCN11A SCN8A SCN9A

2.08e-07677316029194
Pubmed

Roles of I(f) and intracellular Ca2+ release in spontaneous activity of ventricular cardiomyocytes during murine embryonic development.

RYR1 RYR3 ITPR2

2.08e-07677323463619
Pubmed

Are voltage-dependent ion channels involved in the endothelial cell control of vasomotor tone?

SCN11A SCN2A SCN8A

2.08e-07677317513486
Pubmed

A calcium-induced calcium release mechanism supports luteinizing hormone-induced testosterone secretion in mouse Leydig cells.

RYR1 RYR3 ITPR2

2.08e-07677320519450
Pubmed

Essential Roles of Intracellular Calcium Release Channels in Muscle, Brain, Metabolism, and Aging.

RYR1 RYR3 ITPR2

2.08e-07677325966694
Pubmed

An animal model of oxaliplatin-induced cold allodynia reveals a crucial role for Nav1.6 in peripheral pain pathways.

SCN11A SCN3A SCN8A

2.08e-07677323711479
Pubmed

IP3Rs are sufficient for dendritic cell Ca2+ signaling in the absence of RyR1.

RYR1 RYR3 ITPR2

2.08e-07677316844763
Pubmed

Diagnostic yield of genetic testing in epileptic encephalopathy in childhood.

SCN1A SCN2A SCN8A

3.63e-07777325818041
Pubmed

Tyrosine-phosphorylated and nonphosphorylated sodium channel beta1 subunits are differentially localized in cardiac myocytes.

SCN1A SCN5A SCN8A

3.63e-07777315272007
Pubmed

Developmental expression of the calcium release channels during early neurogenesis of the mouse cerebral cortex.

RYR1 RYR3 ITPR2

3.63e-07777311860456
Pubmed

Pain without nociceptors? Nav1.7-independent pain mechanisms.

SCN11A SCN3A SCN9A

3.63e-07777324440715
Pubmed

Roles of IP3R and RyR Ca2+ channels in endoplasmic reticulum stress and beta-cell death.

RYR1 RYR3 ITPR2

5.80e-07877319033399
Pubmed

Significant determinants of mouse pain behaviour.

SCN11A SCN3A SCN9A

5.80e-07877325101983
Pubmed

Sodium channel Scn1b null mice exhibit prolonged QT and RR intervals.

SCN1A SCN5A SCN8A

8.68e-07977317884088
Pubmed

Quantitative trait loci mapping of genes that influence the sensitivity and tolerance to ethanol-induced hypothermia in BXD recombinant inbred mice.

SCN1A SCN2A SCN3A

2.26e-06127738169823
Pubmed

Confirmation of quantitative trait loci for alcohol preference in mice.

SCN1A SCN2A SCN3A

4.66e-06157739726281
Pubmed

Association between SCN1A and SCN2A mutations and clinical/EEG features in Chinese patients from epilepsy or severe seizures.

SCN1A SCN2A

4.84e-06277229649454
Pubmed

Array-CGH detection of a de novo 2.8 Mb deletion in 2q24.2-->q24.3 in a girl with autistic features and developmental delay.

SCN2A SCN3A

4.84e-06277220346423
Pubmed

Reduction of Kcnt1 is therapeutic in mouse models of SCN1A and SCN8A epilepsy.

SCN1A SCN8A

4.84e-06277237901435
Pubmed

An Scn1a epilepsy mutation in Scn8a alters seizure susceptibility and behavior.

SCN1A SCN8A

4.84e-06277226410685
Pubmed

Structural analysis and detection of biological inositol pyrophosphates reveal that the family of VIP/diphosphoinositol pentakisphosphate kinases are 1/3-kinases.

PPIP5K1 PPIP5K2

4.84e-06277218981179
Pubmed

Neuronal death and perinatal lethality in voltage-gated sodium channel alpha(II)-deficient mice.

SCN1A SCN2A

4.84e-06277210827969
Pubmed

Differential role of sodium channels SCN1A and SCN2A gene polymorphisms with epilepsy and multiple drug resistance in the north Indian population.

SCN1A SCN2A

4.84e-06277219694741
Pubmed

Commonalities and distinctions between two neurodevelopmental disorder subtypes associated with SCN2A and SCN8A variants and literature review.

SCN2A SCN8A

4.84e-06277235348308
Pubmed

Genomic structures of SCN2A and SCN3A - candidate genes for deafness at the DFNA16 locus.

SCN2A SCN3A

4.84e-06277211245985
Pubmed

Kinetic Analysis of Membrane Potential Dye Response to NaV1.7 Channel Activation Identifies Antagonists with Pharmacological Selectivity against NaV1.5.

SCN5A SCN9A

4.84e-06277226861708
Pubmed

Electrophysiological properties of two axonal sodium channels, Nav1.2 and Nav1.6, expressed in mouse spinal sensory neurones.

SCN2A SCN8A

4.84e-06277215760941
Pubmed

Principal mutation hotspot for central core disease and related myopathies in the C-terminal transmembrane region of the RYR1 gene.

RYR1 RYR3

4.84e-06277212565913
Pubmed

Contractile impairment and structural alterations of skeletal muscles from knockout mice lacking type 1 and type 3 ryanodine receptors.

RYR1 RYR3

4.84e-0627729489997
Pubmed

Functional and morphological features of skeletal muscle from mutant mice lacking both type 1 and type 3 ryanodine receptors.

RYR1 RYR3

4.84e-0627729192302
Pubmed

Differential expression of two sodium channel subtypes in human brain.

SCN1A SCN2A

4.84e-0627721317301
Pubmed

The block of ryanodine receptors selectively inhibits fetal myoblast differentiation.

RYR1 RYR3

4.84e-06277212640042
Pubmed

Duplication of the sodium channel gene cluster on 2q24 in children with early onset epilepsy.

SCN2A SCN3A

4.84e-06277223016767
Pubmed

Whole gene duplication of SCN2A and SCN3A is associated with neonatal seizures and a normal intellectual development.

SCN2A SCN3A

4.84e-06277227153334
Pubmed

Effects of SCN1A and SCN2A polymorphisms on responsiveness to valproic acid monotherapy in epileptic children.

SCN1A SCN2A

4.84e-06277233096315
Pubmed

Electrophysiological Differences between the Same Pore Region Mutation in SCN1A and SCN3A.

SCN1A SCN3A

4.84e-06277224990319
Pubmed

Na+ current properties in islet α- and β-cells reflect cell-specific Scn3a and Scn9a expression.

SCN3A SCN9A

4.84e-06277225172946
Pubmed

Clinical exome sequencing identifies two novel mutations of the SCN1A and SCN2A genes in Moroccan patients with epilepsy: a case series.

SCN1A SCN2A

4.84e-06277231439038
Pubmed

Isolation and partial cloning of ryanodine-sensitive Ca2+ release channel protein isoforms from human myometrial smooth muscle.

RYR1 RYR3

4.84e-0627727556644
Pubmed

Possible involvement of ryanodine receptor-mediated intracellular calcium release in the effect of corticotropin-releasing factor on adrenocorticotropin secretion.

RYR1 RYR3

4.84e-06277214592949
Pubmed

A genome-wide association study identifies a novel susceptibility locus for renal cell carcinoma on 12p11.23.

CEP85L ITPR2

4.84e-06277222010048
Pubmed

Purification, sequencing, and molecular identification of a mammalian PP-InsP5 kinase that is activated when cells are exposed to hyperosmotic stress.

PPIP5K1 PPIP5K2

4.84e-06277217702752
Pubmed

Mutation in the neuronal voltage-gated sodium channel SCN1A in familial hemiplegic migraine.

SCN1A SCN5A

4.84e-06277216054936
Pubmed

Sodium channel expression within chronic multiple sclerosis plaques.

SCN2A SCN8A

4.84e-06277217805013
Pubmed

Comparative structural analysis of human Nav1.1 and Nav1.5 reveals mutational hotspots for sodium channelopathies.

SCN1A SCN5A

4.84e-06277233712547
Pubmed

Ryanodine receptors in muscarinic receptor-mediated bronchoconstriction.

RYR1 RYR3

4.84e-06277215894801
Pubmed

Missense mutations in sodium channel SCN1A and SCN2A predispose children to encephalopathy with severe febrile seizures.

SCN1A SCN2A

4.84e-06277226311622
Pubmed

Aberrant regulation of a poison exon caused by a non-coding variant in a mouse model of Scn1a-associated epileptic encephalopathy.

SCN1A SCN8A

4.84e-06277233411788
Pubmed

Scn8a Antisense Oligonucleotide Is Protective in Mouse Models of SCN8A Encephalopathy and Dravet Syndrome.

SCN1A SCN8A

4.84e-06277231943325
Pubmed

Severe epilepsy, retardation, and dysmorphic features with a 2q deletion including SCN1A and SCN2A.

SCN1A SCN2A

4.84e-06277215249644
Pubmed

Mapping of a FEB3 homologous febrile seizure locus on mouse chromosome 2 containing candidate genes Scn1a and Scn3a.

SCN1A SCN3A

4.84e-06277227690330
Pubmed

Morphological abnormalities of adrenal gland and hypertrophy of liver in mutant mice lacking ryanodine receptors.

RYR1 RYR3

4.84e-0627729799464
Pubmed

Effect of delta-opioid receptor over-expression on cortical expression of GABAA receptor alpha1-subunit in hypoxia.

OPRD1 GABRA1

4.84e-06277221789893
Pubmed

Effect of calmodulin on Ca2+-induced Ca2+ release of skeletal muscle from mutant mice expressing either ryanodine receptor type 1 or type 3.

RYR1 RYR3

4.84e-0627729817784
Pubmed

Painful and painless mutations of SCN9A and SCN11A voltage-gated sodium channels.

SCN11A SCN9A

4.84e-06277232601768
Pubmed

Sodium channel slow inactivation interferes with open channel block.

SCN8A SCN9A

4.84e-06277227174182
Pubmed

The developmental changes of Na(v)1.1 and Na(v)1.2 expression in the human hippocampus and temporal lobe.

SCN1A SCN2A

4.84e-06277221377452
Pubmed

The Significance of the Bifunctional Kinase/Phosphatase Activities of Diphosphoinositol Pentakisphosphate Kinases (PPIP5Ks) for Coupling Inositol Pyrophosphate Cell Signaling to Cellular Phosphate Homeostasis.

PPIP5K1 PPIP5K2

4.84e-06277228126903
Pubmed

Reduced expression of Na(v)1.6 sodium channels and compensation by Na(v)1.2 channels in mice heterozygous for a null mutation in Scn8a.

SCN2A SCN8A

4.84e-06277218601978
Pubmed

The double face of the histone variant H3.3.

H3Y2 H3Y1

4.84e-06277221263457
Pubmed

Correlations in timing of sodium channel expression, epilepsy, and sudden death in Dravet syndrome.

SCN1A SCN3A

4.84e-06277223965409
Pubmed

Evaluating the Role of Genetic Variants on first-line antiepileptic drug response in North India: Significance of SCN1A and GABRA1 Gene Variants in Phenytoin Monotherapy and its Serum Drug Levels.

SCN1A GABRA1

4.84e-06277227245092
Pubmed

FGF14 N-terminal splice variants differentially modulate Nav1.2 and Nav1.6-encoded sodium channels.

SCN2A SCN8A

4.84e-06277219465131
Pubmed

Isoform-specific effects of the beta2 subunit on voltage-gated sodium channel gating.

SCN2A SCN5A

4.84e-06277216847056
Pubmed

Specialized functions of Nav1.5 and Nav1.9 channels in electrogenesis of myenteric neurons in intact mouse ganglia.

SCN11A SCN5A

4.84e-06277224719102
Pubmed

Epigenetic regulation of Kaposi's sarcoma-associated herpesvirus latency by virus-encoded microRNAs that target Rta and the cellular Rbl2-DNMT pathway.

RBL2 DNMT1

4.84e-06277220071580
Pubmed

Persistent Nav1.1 and Nav1.6 currents drive spinal locomotor functions through nonlinear dynamics.

SCN1A SCN8A

4.84e-06277237665666
Pubmed

Cloning and characterization of two human VIP1-like inositol hexakisphosphate and diphosphoinositol pentakisphosphate kinases.

PPIP5K1 PPIP5K2

4.84e-06277217690096
Pubmed

The voltage-gated sodium channel Scn8a is a genetic modifier of severe myoclonic epilepsy of infancy.

SCN1A SCN8A

4.84e-06277217881658
Pubmed

Expression and functional activity of ryanodine receptors (RyRs) during skeletal muscle development.

RYR1 RYR3

4.84e-06277217118445
Pubmed

SCN1A and SCN2A polymorphisms are associated with response to valproic acid in Chinese epilepsy patients.

SCN1A SCN2A

4.84e-06277230693367
InteractionSCN11A interactions

SCN11A SCN1A SCN5A SCN8A SCN9A

1.70e-0915745int:SCN11A
InteractionSCN5A interactions

SCN11A SCN1A SCN5A BANP SCN8A SCN9A

1.90e-0847746int:SCN5A
InteractionCACNA1D interactions

SCN11A SCN1A SCN5A SCN9A VIRMA

2.34e-0824745int:CACNA1D
InteractionNALCN interactions

SCN11A SCN1A SCN5A SCN9A

1.63e-0714744int:NALCN
InteractionMYPN interactions

PHLPP1 MCM2 VIRMA BAG6 RYR1

3.46e-0740745int:MYPN
InteractionSCN9A interactions

SCN11A SCN1A SCN5A SCN9A

9.56e-0721744int:SCN9A
InteractionSCN4B interactions

SCN1A SCN2A SCN8A

2.63e-068743int:SCN4B
InteractionSCN1A interactions

SCN11A SCN1A SCN5A SCN9A

3.71e-0629744int:SCN1A
InteractionCACNA1A interactions

SCN11A ABCA2 SCN1A SCN5A SCN9A CKAP5

6.03e-06123746int:CACNA1A
InteractionSCN10A interactions

SCN11A SCN1A SCN5A

7.68e-0611743int:SCN10A
InteractionCACNA1B interactions

SCN11A SCN1A SCN5A SCN9A

1.01e-0537744int:CACNA1B
InteractionYWHAH interactions

KIF21B FAM171A1 NCOA3 MTMR12 ABCA2 TRIO CEP85L CKAP5 TRAPPC10 MCM2 PPIP5K2 VIRMA TESPA1 DNMT1

4.13e-0511027414int:YWHAH
InteractionSCN8A interactions

SCN11A SCN5A SCN8A

5.18e-0520743int:SCN8A
InteractionCACNA1C interactions

SCN11A SCN1A SCN5A SCN9A

7.46e-0561744int:CACNA1C
InteractionPIK3C2G interactions

BANP VIRMA

7.94e-054742int:PIK3C2G
InteractionANTKMT interactions

MKRN3 BANP BAG6

1.16e-0426743int:ANTKMT
CytobandEnsembl 112 genes in cytogenetic band chr2q24

SCN1A SCN2A SCN3A SCN9A GCA

2.52e-06127775chr2q24
Cytoband2q24

SCN3A SCN9A

1.51e-04117722q24
Cytoband2q24.3

SCN1A SCN2A

3.28e-04167722q24.3
Cytoband5p13.3

MTMR12 DROSHA

7.48e-04247725p13.3
Cytoband5p15.1

H3Y2 H3Y1

1.42e-03337725p15.1
Cytoband3p21.1

ALAS1 DNAH1

2.29e-03427723p21.1
GeneFamilySodium voltage-gated channel alpha subunits

SCN11A SCN1A SCN2A SCN3A SCN5A SCN8A SCN9A

3.32e-1795171203
GeneFamilyDyneins, axonemal

DNAL4 DNAH9 DNAH1

1.40e-0517513536
GeneFamilyRyanodine receptors|Protein phosphatase 1 regulatory subunits

RYR1 RYR3

2.34e-053512287
CoexpressionMANNO_MIDBRAIN_NEUROTYPES_HNBGABA

KIF21B FRY ZBTB38 SCN1A SCN2A SCN3A SCN8A CTNNA3 SCN9A CHN1 WDFY4 GABRA1

7.03e-077037512M39070
CoexpressionTORCHIA_TARGETS_OF_EWSR1_FLI1_FUSION_UP

NCOA3 FRY MTMR12 RBL2 ADCY9 MVD FAAH

1.37e-05274757M2348
CoexpressionMANNO_MIDBRAIN_NEUROTYPES_HGABA

EBF2 KIF21B FRY ZBTB38 ATP8A1 CEP85L SCN1A SCN2A SCN3A SCN8A SCN9A CHN1 GABRA1

1.39e-0511067513M39071
CoexpressionTORCHIA_TARGETS_OF_EWSR1_FLI1_FUSION_UP

NCOA3 FRY MTMR12 RBL2 ADCY9 MVD FAAH

1.47e-05277757MM917
CoexpressionAtlasDevelopingKidney_e15.5_Endothelial cells_emap-29977_k-means-cluster#3_top-relative-expression-ranked_500

DOCK1 FAM171A1 TRIO ARFGEF2

1.54e-0625734DevelopingKidney_e15.5_Endothelial cells_emap-29977_k3_500
CoexpressionAtlasBM Top 100 - parietal lobe

SCN1A SCN2A CHN1 TESPA1 GABRA1

5.98e-0675735BM Top 100 - parietal lobe
CoexpressionAtlasDevelopingKidney_e15.5_Endothelial cells_emap-29977_k-means-cluster#3_top-relative-expression-ranked_1000

DOCK1 FAM171A1 NCOA3 TRIO ARFGEF2

1.54e-0591735DevelopingKidney_e15.5_Endothelial cells_emap-29977_k3_1000
CoexpressionAtlasDevelopingKidney_e15.5_Peripheral blastema_emap-27731_k-means-cluster#2_top-relative-expression-ranked_500

ATP8A1 SCN1A SCN3A GCA LDB2 GABRA1

7.68e-05206736gudmap_developingKidney_e15.5_Peripheral blastema_500_k2
CoexpressionAtlascerebral cortex

MKRN3 SHISA9 KIF21B ABCA2 SCN1A SCN2A SCN3A SCN8A CTNNA3 PPP1R16B LHX5 CHN1 KCNIP1 OPRD1 GABRA1

8.64e-0514287315cerebral cortex
CoexpressionAtlasdev lower uro neuro_e15.5_PelvicGanglion_Sox10_k-means-cluster#1_top-relative-expression-ranked_1000

FRY ATP8A1 SCN2A SCN3A SCN9A RYR3

8.77e-05211736gudmap_dev lower uro neuro_e15.5_PelvicGanglion_Sox10_k1_1000
CoexpressionAtlasBM Top 100 - cerebral cortex

SCN1A SCN2A CHN1 GABRA1

1.11e-0472734BM Top 100 - cerebral cortex
CoexpressionAtlasBM Top 100 - occipital lobe

SCN1A SCN2A CHN1 GABRA1

1.17e-0473734BM Top 100 - occipital lobe
CoexpressionAtlasalpha beta T cells, NKT.4-.Sp, TCRbeta+ aGalCer tet+ CD4-, Spleen, avg-3

ZBTB38 TRIO RBL2 PPP1R16B TESPA1 FAAH ITPR2

1.42e-04331737GSM538329_500
CoexpressionAtlaskidney_adult_GlomCapSys_Tie2_k-means-cluster#3_top-relative-expression-ranked_1000

FAM171A1 NCOA3 ATP8A1 PPP1R16B PHLPP1 LDB2

1.98e-04245736gudmap_kidney_adult_GlomCapSys_Tie2_k3_1000
CoexpressionAtlasDevelopingKidney_e15.5_Endothelial cells_emap-29965_k-means-cluster#5_top-relative-expression-ranked_1000

DOCK1 FAM171A1 TRIO ARFGEF2

2.01e-0484734gudmap_developingKidney_e15.5_Endothelial cells_1000_k5
CoexpressionAtlasalpha beta T cells, NKT.4-.Lv, CD45 TCRb aGalCer-loaded CD1d tet, Liver, avg-4

ZBTB38 TRIO RBL2 PPP1R16B TESPA1 FAAH ITPR2

2.03e-04351737GSM538325_500
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-kidney_connecting_tubule_epithelial_cell-Connecting_Tubule_Principal_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

WSB1 FAM171A1 SCN2A SCN3A ALAS1 KCNIP1

7.78e-07183776d340ab5a77e8d819a1dfb4ca3e9a4b9bc988923c
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic-thymocyte|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GUCY2F SCN2A SCN9A DNAH9 RYR3 DNAH1

8.03e-071847762cbed6462fea2622871bb7e49b0df3d984239281
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GUCY2F SCN2A SCN9A DNAH9 RYR3 DNAH1

8.03e-07184776ea7a7e2bac46d4d2c31a5d576b38a032b5335062
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic-proliferating_thymocyte;_DN_to_DP_transition,_dividing_(some_are_Cd8+/_Cd4+,_some_undergoing_VDJ_recombination)|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GUCY2F SCN2A SCN9A DNAH9 RYR3 DNAH1

8.03e-071847762b19a8c5f823e00812908b23e66bb4e563278aff
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Collecting_tubule_epithelial_cell-kidney_connecting_tubule_epithelial_cell-Connecting_Tubule_Principal_Cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

WSB1 FAM171A1 FRY SCN2A SCN3A KCNIP1

8.83e-07187776f6217d0dd425eac76900b44a4e48f45475f3ac36
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Collecting_tubule_epithelial_cell-kidney_connecting_tubule_epithelial_cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

WSB1 FAM171A1 FRY SCN2A SCN3A KCNIP1

9.39e-071897768ff3c3232eff9de4b5c9b22ecb82bc509d773f58
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Collecting_tubule_epithelial_cell-kidney_connecting_tubule_epithelial_cell-Connecting_Tubule_Cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

WSB1 FAM171A1 FRY SCN2A SCN3A KCNIP1

9.69e-071907764836ea19308d2a96694f12ab0653b7ce7b101d2f
ToppCellPCW_07-8.5-Epithelial-Epithelial_airway-epi_proximal_secretory_(0)|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

SHISA9 FRY ATP8A1 CTNNA3 SCN9A GABRA1

9.99e-0719177660ff989fe99d243a3d52955223680cdd1f1917a4
ToppCellPCW_07-8.5-Epithelial-Epithelial_airway|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

SHISA9 FRY ATP8A1 CTNNA3 SCN9A GABRA1

1.09e-06194776f95c8dc242c9aebcadfe61b1ed033349cb7e5a88
ToppCellMid-temporal_gyrus_(MTG)-Neuronal|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

SHISA9 FRY SCN2A SCN3A SCN8A GABRA1

1.16e-06196776676c56b44ac29f7baecb62f49bb8597cc74c0a88
ToppCellSomatosensory_Cortex_(S1)-Neuronal|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

FRY SCN1A SCN2A SCN3A SCN8A GABRA1

1.23e-06198776c01091ef18e096d792ea2a7a715764a5b215355f
ToppCellprimary_auditory_cortex_(A1C)-Neuronal|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

FRY SCN1A SCN2A SCN3A SCN8A GABRA1

1.23e-061987766d18b45eda4014759e6dd282d78ffd28df8a6044
ToppCellPrimary_Visual_cortex_(V1C)-Neuronal|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

FRY SCN1A SCN2A SCN8A CHN1 GABRA1

1.23e-061987768ab40fae14fe02e39bc8c8da187a5cd60c787643
ToppCellPrimary_Motor_Cortex_(M1)-Neuronal|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

FRY SCN1A SCN2A SCN3A SCN8A GABRA1

1.23e-061987764ca5ff320905ab4ff60ed90a5522227c782142a6
ToppCellMacroglial-Polydendrocytes-PDGFRA-|Macroglial / cells hierarchy compared to all cells using T-Statistic

SHISA9 FRY SCN1A SCN2A SCN3A SCN9A

1.31e-06200776f17b5a54e8f9eba9dcd0808ba4e8d275ac41bce2
ToppCellMacroglial-Polydendrocytes-PDGFRA--|Macroglial / cells hierarchy compared to all cells using T-Statistic

SHISA9 FRY SCN1A SCN2A SCN3A SCN9A

1.31e-06200776cc3409518f8b436ea92deb955e81114b3f410ff7
ToppCellMacroglial-Polydendrocytes-PDGFRA|Macroglial / cells hierarchy compared to all cells using T-Statistic

SHISA9 FRY SCN1A SCN2A SCN3A SCN9A

1.31e-06200776c24a3099e3d96d8b72f6d05286bb355d661a0377
ToppCellMacroglial-Polydendrocytes-PDGFRA---|Macroglial / cells hierarchy compared to all cells using T-Statistic

SHISA9 FRY SCN1A SCN2A SCN3A SCN9A

1.31e-062007764fc3de4bff7ed2bf40b38462c4b4e9b87af6a4ca
ToppCellMacroglial-Polydendrocytes-PDGFRA----L1-6|Macroglial / cells hierarchy compared to all cells using T-Statistic

SHISA9 FRY SCN1A SCN2A SCN3A SCN9A

1.31e-06200776310cd53db1c137f6af74e6ae682221d7ac27310c
ToppCellMacroglial-Polydendrocytes|Macroglial / cells hierarchy compared to all cells using T-Statistic

SHISA9 FRY SCN1A SCN2A SCN3A SCN9A

1.31e-06200776961858738ce35db8760c8c2e136f8369bc444ccf
ToppCellPBMC_fresh-frozen-Severe-critical_convalescent_d14-21-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD4_c07-AHNAK|Severe-critical_convalescent_d14-21 / Compartment, severity and other cell annotations on 10x 3' data (130k)

MKRN3 EBF2 FAM171A1 CHN1 DMBX1

5.32e-06145775c0894c738815ff54790caddb4bccfa1503fd555b
ToppCellsaliva-Severe-critical_progression_d28-40-Lymphocytic-Lymphocytic_T-CD8-positive,_alpha-beta_T_cell-T_CD8_c03-GZMK|Severe-critical_progression_d28-40 / Compartment, severity and other cell annotations on 10x 3' data (130k)

ATP8A1 SCN3A PPP1R16B KDM5D TESPA1

8.85e-06161775d72c572613f8eff3251cb7b1e9dcc76d193b2f21
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial-Ascending_Vasa_Recta_Endothelial_Cell_prolif|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

PPP1R16B MCM2 CHN1 LDB2 GABRA1

9.96e-061657756a621b300442c52adfc15b61d3a6d3a3cb00099f
ToppCellEndothelial-B-Donor_02|World / lung cells shred on cell class, cell subclass, sample id

FAM171A1 AVPR2 SCN3A KCNIP1 LDB2

1.12e-051697758889c9e8af1ab0b093d57b69abd80b59b3461be9
ToppCellfacs-Diaphragm-Limb_Muscle-24m|Diaphragm / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SCN3A SCN9A DNAH9 RYR3 DNAH1

1.12e-0516977512bdc709bc000d7f9061ecd9fbd57233eaacb7e2
ToppCellsaliva-Severe-critical_progression_d28-40-Lymphocytic-Lymphocytic_T-CD8-positive,_alpha-beta_T_cell|Severe-critical_progression_d28-40 / Compartment, severity and other cell annotations on 10x 3' data (130k)

ATP8A1 SCN3A PPP1R16B KDM5D TESPA1

1.56e-05181775986c036e656f24fe374807e2711cec9e3c83c892
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell-Outer_Medullary_Collecting_Duct_Principal_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

FRY SCN2A LHX5 KCNIP1 ADCY9

1.56e-05181775aa233b652921848af2257cc3687a7a09c3acfb67
ToppCellfacs-GAT-Fat-3m-Lymphocytic-T_cell|GAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ABCA2 PPP1R16B MEI1 TESPA1 FAAH

1.60e-05182775751bd3e3b49de961523e98197688a05c998c121a
ToppCell5'-Airway_Nasal-Immune_Myeloid_mast-Myeloid_Mast/Baso-mast_cell-Mast_cells-|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

DROSHA SCN2A BANP KCNIP1 TESPA1

1.60e-051827754cd5eb13f78f4f377932c50ac2acb4ac0cd14c12
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_connecting_tubule_epithelial_cell-Degenerative_Connecting_Tubule_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

WSB1 FAM171A1 SCN2A SCN3A KCNIP1

1.69e-051847759690d4290e70f9bda889754ffb30b0af1f7cb94b
ToppCellSomatosensory_Cortex_(S1)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_C_(IT_L4_RORB)|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

SCN9A CHN1 TESPA1 LDB2 ITPR2

1.69e-051847756475a43201b136dcc9b113d2ca4cfa154ed9d65d
ToppCelldroplet-Heart-4Chambers-21m-Endothelial-leukocyte|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MKRN3 ATP8A1 SCN3A SCN5A RYR3

1.73e-05185775bb5a4cf93534b9bcd0923f314c389d571e91e7f8
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-kidney_connecting_tubule_epithelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

WSB1 FAM171A1 SCN2A SCN3A KCNIP1

1.78e-0518677508632045d499e61dd96ff29a5a9a208afe58dc58
ToppCellwk_15-18-Hematologic-Myeloid-Basophil|wk_15-18 / Celltypes from embryonic and fetal-stage human lung

KIF21B ABCA2 CTNNA3 PPP1R16B TESPA1

1.87e-051887753638d85452de15a060146628fbbad9d2a36feb13
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_connecting_tubule_epithelial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

WSB1 FAM171A1 SCN2A SCN3A KCNIP1

1.87e-051887754154f4787483c7e076e87a187733a9f666742c3d
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_connecting_tubule_epithelial_cell-Connecting_Tubule_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

WSB1 FAM171A1 SCN2A SCN3A KCNIP1

1.92e-0518977590aae7e806882bebfad78a78e9a16cf56af3ecd4
ToppCellPCW_07-8.5-Epithelial-Epithelial_airway-epi_proximal_progenitor1_(6)|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

FRY ATP8A1 CTNNA3 SCN9A GABRA1

1.92e-051897757659c7bbd58ee959a159294fb8d17317bbcc5681
ToppCellCOVID-19-Heart|COVID-19 / Disease (COVID-19 only), tissue and cell type

EBF2 FRY SCN5A CTNNA3 KLHL31

1.97e-05190775918ad5037881212008f9f69d5df5da91fd01422c
ToppCellBrain_organoid-organoid_Kanton_Nature-Organoid-4M-Neuronal-ventral_progenitors_and_neurons_1|Organoid-4M / Sample Type, Dataset, Time_group, and Cell type.

FRY SCN2A SCN3A SCN9A GABRA1

1.97e-051907756e92c78799f34b31d098854503c796edb0dc7f80
ToppCellPrimary_Visual_cortex_(V1C)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_C_(IT_L4_RORB)|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

NCOA3 SCN1A KCNIP1 GABRA1 ITPR2

1.97e-051907751bbbf0ce222e51f9fd2daca0c18d3965fd4efd31
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_connecting_tubule_epithelial_cell-Connecting_Tubule_Principal_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

WSB1 FAM171A1 SCN2A SCN3A KCNIP1

2.02e-0519177596b78b4e819ea6052334bfcbc7abbf35897df885
ToppCell10x_3'_v2v3-Non-neoplastic-Glial-Neuronal-Oligodendrocyte-Oligodendrocyte-E|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

DOCK1 FAM171A1 ABCA2 ATP8A1 PPP1R16B

2.17e-05194775cb0422e7607dbd77204428b7e2c70dfe14a6ca11
ToppCellsaliva-Severe-critical_progression_d28-40-Lymphocytic|Severe-critical_progression_d28-40 / Compartment, severity and other cell annotations on 10x 3' data (130k)

ATP8A1 CEP85L PPP1R16B KDM5D TESPA1

2.28e-05196775c9fb81a0578db6d278b8582d7b3add6c407e6dcf
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

PPP1R16B PHLPP1 CHN1 LDB2 RYR3

2.34e-05197775cd509e49bbdbf991cc5913960ff3ef275ad40628
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell-Peritubular_Capilary_Endothelial_Cell_|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

PPP1R16B PHLPP1 CHN1 LDB2 RYR3

2.34e-05197775412cb5f37df57121ddd1492021445479c7cbccbf
ToppCellAnterior_Cingulate_gyrus_(CgG)-Neuronal|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

FRY SCN2A SCN3A SCN8A GABRA1

2.40e-051987750ff30edfd3c133a42e8cb96e1631a1143215f808
ToppCellLPS_IL1RA_TNF-Endothelial-Endothelial-Vein|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type

FAM171A1 FRY CHN1 LDB2 ITPR2

2.52e-052007757eb366b2c5394af7c77650bde6261e7dac67154e
ToppCellNeuronal|World / cells hierarchy compared to all cells using T-Statistic

FRY SCN2A SCN3A SCN8A GABRA1

2.52e-0520077548d801219bc771d6c7e151dc88ca4c179988de85
ToppCellBrain_organoid-organoid_Tanaka_cellReport-10w-Neuronal|10w / Sample Type, Dataset, Time_group, and Cell type.

EBF2 KIF21B SCN2A SCN3A LHX5

2.52e-05200775979258173b82f37aeaaedd53b4a527da1dbe1b80
ToppCellCOVID-19-kidney-Epithelial_(EC)|COVID-19 / Disease (COVID-19 only), tissue and cell type

H3Y1 DMBX1 LDB2 RYR3

8.36e-05133774a8abb6b54862123961ae6defbf251ee6e9575258
ToppCellP03-Hematopoietic-Erythroid|P03 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

GLS2 DROSHA PPP1R16B RYR1

1.14e-041447742ee6a834860eac7ed004f366ab4fc38c4b80c905
ToppCellP03-Hematopoietic-Erythroid-enucleate_erythrocyte|P03 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

GLS2 DROSHA PPP1R16B RYR1

1.14e-041447749fa63904389f4d7163db22ea85ab721d8f6e8d99
ToppCell10x_3'_v2v3-Non-neoplastic-Glial-Neuronal-OPC-OPC-E|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

SHISA9 SCN1A SCN2A SCN3A

1.51e-0415577477fdae85d36efb776db977eb424b32487ef222e4
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Endothelial-blood_vessel_endothelial_cell_of_kidney-Degenerative_Endothelial_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

PDHB PPP1R16B CHN1 LDB2

1.55e-04156774ea9223bb6450b22df11efa1705ab72dab005244a
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Endothelial-blood_vessel_endothelial_cell_of_kidney-Degenerative_Endothelial_Cell-Degenerative_Peritubular_Capilary_Endothelial_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

PDHB PPP1R16B CHN1 LDB2

1.55e-04156774586b5509074c4cc359e9e31a968c2ded71c994ca
ToppCell10x5'-Lung-Myeloid_Monocytic-Cycling_mono|Lung / Manually curated celltypes from each tissue

MCM2 PPIP5K1 VIRMA FAAH

1.55e-0415677463b8cf14361b282872bc1c5b65d9fbc83e81a089
ToppCellBrain_organoid-organoid_Kanton_Nature-Organoid-1M-Neuronal-cortical_neurons_1|Organoid-1M / Sample Type, Dataset, Time_group, and Cell type.

NADSYN1 TRIO SCN1A KCNIP1

1.62e-041587741f94622186d8329357fa06785e03eeacf29ab1ce
ToppCellCOVID-19-kidney-Epithelial_(EC)|kidney / Disease (COVID-19 only), tissue and cell type

CTNNA3 H3Y1 DMBX1 LDB2

1.70e-041607740d4880f85565d8c540c94a8f8109147b3029279a
ToppCellkidney_cells-Renal_AKI_(acute_kidney_injury)-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell-Cortical_Collecting_Duct_Principal_Cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

WSB1 AVPR2 SCN2A ALAS1

1.70e-041607747064af50fc10e3ea03badf415306222b74db0f95
ToppCellPND07-Endothelial-Endothelial_lymphatic|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

SCN11A SCN1A SCN3A SCN5A

1.74e-04161774133b4fadb499e842c19f573f9cf09ce08c1d4813
ToppCellPND07-Endothelial-Endothelial_lymphatic-Lymphatic_EC|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

SCN11A SCN1A SCN3A SCN5A

1.74e-041617749466b8658244116f8d21f2f88fb8c2d184b1bdf2
ToppCell343B-Myeloid-Dendritic-cDC1|Dendritic / Donor, Lineage, Cell class and subclass (all cells)

DNAL4 SCN3A C8B WDFY4

1.74e-04161774537a1d86de99a493b0345ca0f760994260e97049
ToppCellPND07-Endothelial-Endothelial_lymphatic-Lymphatic_EC-LEC|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

SCN11A SCN1A SCN3A SCN5A

1.74e-04161774cb177ca10d848d0e25399ab5ebfcde1071fb94c2
ToppCelldroplet-Heart-nan-24m-Hematologic-nan|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

KIF21B WDFY4 TESPA1 RYR1

1.74e-041617747e60001637ef0f6fc67ef8a36ab80ebb25b0b0ab
ToppCellkidney_cells-Adult_normal_reference-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell-Distal_Convoluted_Tubule_Cell_Type_2|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

WSB1 FAM171A1 ATP8A1 SCN2A

1.79e-0416277436ddebe3bb172c992739353b7b049b2dde98b559
ToppCellPND07-Endothelial-Endothelial_lymphatic-Lymphatic_EC-LEC-LEC_mature|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

SCN11A SCN1A SCN3A SCN5A

1.79e-0416277496c6e94a10b124a1d25dcd705ec5aaa8609c1089
ToppCellMild-Myeloid-Mast|Mild / Condition, Lineage, Cell class and cell subclass

SCN5A SCN9A KCNIP1 TESPA1

1.92e-041657745fa9552c37890c5cc7e672a47038aebba2413cb4
ToppCellMild-Myeloid-Mast-|Mild / Condition, Lineage, Cell class and cell subclass

SCN5A SCN9A KCNIP1 TESPA1

1.92e-0416577493d3909a0f5f43d473d5005c842d7d73e25eceed
ToppCell356C-Endothelial_cells-Endothelial-F_(Lymphatics)-|356C / Donor, Lineage, Cell class and subclass (all cells)

SCN3A SCN5A KCNIP1 LDB2

1.96e-041667745ba45407a47207ff01e4a3f9f5d91d8247fe9b6f
ToppCell356C-Endothelial_cells-Endothelial-F_(Lymphatics)|356C / Donor, Lineage, Cell class and subclass (all cells)

SCN3A SCN5A KCNIP1 LDB2

1.96e-041667746bd5aa205b6e4b88ba9f8cd0999e2191d7d1d16c
ToppCellEndothelial-B-IPF_01|World / lung cells shred on cell class, cell subclass, sample id

SCN3A PPP1R16B KCNIP1 LDB2

1.96e-04166774c286987ea4e511195607c87ec4529c2c2ed2122e
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Degenerative_Proximal_Tubule_Epithelial_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

CTNNA3 DNAH9 RYR1 OPRD1

2.01e-041677743edb0570e583bb527165bcd8a4c25a042054043b
ToppCell3'-GW_trimst-2-LargeIntestine-Neuronal-Glial_immature-Glia_3_(BCAN+)|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

SHISA9 SCN5A SCN9A PHLPP1

2.10e-041697742456b3e7776e8a2214972be1b4d66a3ca5480ae0
ToppCellfacs-Lung-24m-Hematologic-lymphocytic-CD8-positive,_alpha-beta_T_cell-CD8-positive,_alpha-beta_T_cell_l5|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

AVPR2 DMBX1 RYR3 KLHL31

2.10e-04169774a388e53deac861a185c31e9cceddae7bcb344700
ToppCellfacs-Brain_Non-Myeloid-Cerebellum_-18m-Neuronal-nan|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GLS2 SCN2A LHX5 GABRA1

2.20e-0417177499176a932569fa1c7e1c01009684f5a65244b96e
ToppCellChildren_(3_yrs)-Endothelial-endothelial_cell_of_artery-D032|Children_(3_yrs) / Lineage, Cell type, age group and donor

FAM171A1 PPP1R16B CHN1 LDB2

2.20e-041717741597459c971d6befa991d59dc66b41b6a522f797
ToppCellEndothelial-B-IPF_04|World / lung cells shred on cell class, cell subclass, sample id

FAM171A1 SCN11A SCN3A LDB2

2.25e-04172774d4e98ff9c7cbc95457e1d71fa60f151a2f178dae
ToppCellGlobus_pallidus-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)|Globus_pallidus / BrainAtlas - Mouse McCarroll V32

GLS2 SCN1A KCNIP1 GABRA1

2.30e-041737747e3897868dd3f6e4974f593c60649a543ffc8693
ToppCell5'-Adult-LargeIntestine-Endothelial-lymphatic_endothelial-LEC3_(ADGRG3+)|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

SCN3A KCNIP1 LDB2 KLHL31

2.30e-041737747dc988fc0ba29990567bf1bcdeb3faeeee507eb1
ToppCellAdult-Endothelial-endothelial_cell_of_artery-D175|Adult / Lineage, Cell type, age group and donor

FAM171A1 PPP1R16B CHN1 LDB2

2.40e-041757740a65ddfa8c2e8efb5b5338cf07661cb78157a23c
ToppCellCOVID-19-Heart-VSMC|COVID-19 / Disease (COVID-19 only), tissue and cell type

EBF2 FRY SCN3A CTNNA3

2.40e-041757741125f0d3a5b2388fa77a820dea0288e824d84a82
ToppCellControl-Neuronal_cells-Neuronal_cells|Control / group, cell type (main and fine annotations)

FAM171A1 SCN3A KCNIP1 LDB2

2.45e-0417677498c07d26ba0dc0fe15ca0ea81f633d4591782bd1
ToppCellCOVID-19-Heart-CM_3|COVID-19 / Disease (COVID-19 only), tissue and cell type

FRY SCN5A CTNNA3 KLHL31

2.45e-041767749df7a124ebafb0087da0cda133a394275d7bed81
ToppCellMid-temporal_gyrus_(MTG)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_PVALB_2-Inh_L1-6_PVALB_SCUBE3_(Chandelier_1)|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

SCN5A SCN9A KCNIP1 RYR1

2.45e-0417677495d5a4fdff1b9c715636684d22e06f8727ac0e7a
ToppCellControl-Neuronal_cells|Control / group, cell type (main and fine annotations)

FAM171A1 SCN3A KCNIP1 LDB2

2.45e-04176774c29d09ecf0eb17f767d78af4b7f2e7725c967ff8
ToppCellControl-B_cells|Control / group, cell type (main and fine annotations)

NCOA3 PPP1R16B MEI1 WDFY4

2.45e-041767749125caa27bf790f6b1b960a86c09b4bcb1b58641
ToppCellCOVID-19-lung-B_cells|lung / Disease (COVID-19 only), tissue and cell type

NCOA3 SCN3A PPP1R16B WDFY4

2.50e-04177774f54691e5558091c1734ab15153a10bff15ed171e
ToppCellwk_15-18-Epithelial-PNS-Schwann_precursor|wk_15-18 / Celltypes from embryonic and fetal-stage human lung

SHISA9 SCN1A SCN5A SCN8A

2.50e-041777745357359e6c2161a37f39a6b3b78449f5cbc327d1
ToppCellCOVID-19-B_cells-Activated_B_cells|COVID-19 / group, cell type (main and fine annotations)

NCOA3 SCN3A PPP1R16B WDFY4

2.50e-04177774653bb62a3744d4024ab3186ee01d410ed62832a6
ToppCelldroplet-Heart-nan-3m-Mesenchymal-smooth_muscle_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SCN3A CTNNA3 LHX5 CHN1

2.50e-04177774dbdbdc8ed9ef0b529694242ef9f9f07a42e16005
ToppCellPND07-Endothelial-Endothelial_blood-vessel-Microvascular_EC-CAP1-CAP1_prolif|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

PPP1R16B MCM2 LDB2 DNMT1

2.50e-041777740e74980a7686c31fcf1476b8f19a3392541df240
ToppCelldroplet-Heart-nan-3m-Mesenchymal-smooth_muscle_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SCN3A CTNNA3 LHX5 CHN1

2.56e-04178774416f85e51f45ec7949451fd47611a84e33e87245
ToppCellMid-temporal_gyrus_(MTG)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_PVALB_2|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

SCN5A SCN9A KCNIP1 RYR1

2.61e-041797743b0f8781232e1d42b6f8913bc989a14b3f978e79
ToppCellfacs-SCAT-Fat-3m-Lymphocytic-NK_cell|SCAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SCN5A PPP1R16B TESPA1 FAAH

2.61e-041797746f657c7a227f860934d0dfec9b97d35fd2cedfd2
ToppCellCOVID-19-Heart-Lymph_EC|Heart / Disease (COVID-19 only), tissue and cell type

SCN3A SCN9A KCNIP1 LDB2

2.61e-04179774411620201a860716a8773b92f50f7b94ef34a586
ToppCellhuman_hepatoblastoma-Tumor_cells-T6|Tumor_cells / Sample and Cell Type and Tumor Cluster (all cells)

FRY ATP8A1 CEP85L PPP1R16B

2.61e-0417977414fc8ccb6b215063d747643f47d780d2b237eb67
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell-Distal_Convoluted_Tubule_Cell_Type_2|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

WSB1 FAM171A1 SCN2A SCN3A

2.61e-04179774666072c0e8448dbaec1683d18368ec2502453f90
ToppCellPCW_13-14-Neuronal-Neuronal_postreplicative-neuro_neuronal_(6)|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung

SHISA9 SCN1A SCN2A SCN3A

2.61e-04179774af0b54c9ea0b6e4210f22dbb6e88ecd3276a5f86
ToppCellRSV-Healthy-0|RSV / Virus stimulation, Condition and Cluster

ZBTB38 TRAPPC10 PHLPP1 CHN1

2.67e-04180774974044056e2f7e909cb11c6f6ca89e58bf95f7e5
ToppCellRSV-Healthy-0|Healthy / Virus stimulation, Condition and Cluster

ZBTB38 TRAPPC10 PHLPP1 CHN1

2.67e-04180774703a1d0f9536af94d56757eb01221878d7b7fe61
ComputationalNeighborhood of ARL3

DOCK1 FRY TRIO GUCY2F ARFGEF2 GCA RYR3 GABRA1

3.23e-05304458MORF_ARL3
ComputationalNeighborhood of SUPT3H

FRY TRIO GUCY2F ARFGEF2 GCA RYR1 RYR3 GABRA1

5.55e-05328458MORF_SUPT3H
ComputationalNeighborhood of RAD51L3

FRY TRIO GUCY2F ARFGEF2 GCA RYR1 RYR3 GABRA1

1.76e-04387458MORF_RAD51L3
ComputationalNeighborhood of ERCC4

DOCK1 FRY TRIO GUCY2F GCA RYR3 GABRA1

3.39e-04321457MORF_ERCC4
DrugZonisamide

SCN11A SCN1A SCN2A SCN3A SCN5A SCN9A

1.25e-1117756DB00909
Druglamotrigine

SCN2A SCN3A SCN5A SCN9A RYR1 RYR3 GABRA1

1.11e-07116757CID000003878
Drugflecainide

SCN11A SCN3A SCN5A SCN9A RYR1 RYR3

1.26e-0771756CID000003355
DrugTetrodotoxin

SCN2A SCN3A SCN5A SCN8A SCN9A

2.04e-0740755ctd:D013779
DrugSodium

SCN11A SCN2A SCN3A SCN5A SCN8A SCN9A

3.46e-0784756ctd:D012964
DrugAPETx1, Anthopleura elegantissima

SCN2A SCN3A SCN8A

6.82e-076753ctd:C475726
Druglidocaine

SCN3A SCN5A SCN9A ADCY9 RYR1 RYR3 GABRA1

9.86e-07160757CID000003676
Drugtetradotoxin

SCN11A GUCY2F RBL2 SCN2A SCN3A SCN5A SCN8A SCN9A OPRD1 GABRA1

1.38e-064287510CID000020382
Druggabapentin

SCN3A SCN5A SCN9A MVD RYR1 RYR3 GABRA1

1.42e-06169757CID000003446
Drug2,3,5,6-tetrafluoro-4-methylbenzyl (Z)-(1RS)-cis-3-(2-chloro-3,3,3-trifluoroprop-1-enyl)-2,2-dimethylcyclopropanecarboxylate

SCN2A SCN3A SCN8A

1.90e-068753ctd:C489827
DrugNSC7524

SCN2A SCN3A SCN5A SCN9A ADCY9 RYR1 RYR3

2.33e-06182757CID000005657
DrugRanolazine

SCN5A SCN9A

1.07e-052752DB00243
DrugPhenytoin

SCN1A SCN5A

1.07e-052752DB00252
DrugProcainamide

SCN5A DNMT1

1.07e-052752DB01035
Drug5'-adenylyl (beta,gamma-methylene)diphosphonate

RYR1 RYR3

1.07e-052752ctd:C005147
Drugtetracaine

SCN9A CHN1 ADCY9 RYR1 RYR3

1.07e-0588755CID000005411
Drugpotassium

ACSL1 GLS2 GUCY2F PDHB SCN2A SCN3A SCN5A SCN9A KCNIP1 ADCY9 RYR1 RYR3 GABRA1

2.30e-0510087513CID000000813
Drugriluzole

SCN3A SCN5A SCN9A RYR1 RYR3 GABRA1

2.38e-05174756CID000005070
DrugScorpion Venoms

SCN2A SCN3A SCN9A

2.70e-0518753ctd:D012604
DrugAC1L380G

CHN1 RYR1 RYR3

3.20e-0519753CID000084698
Drug2-hydroxycarbazole

RYR1 RYR3

3.21e-053752CID000093551
Drug1,1'-diheptyl-4,4'-bipyridinium

RYR1 RYR3

3.21e-053752CID000080262
Drugcis-diammineplatinum(II

RYR1 RYR3

3.21e-053752CID000159790
Drug2-hydroxyheptanoic acid

RYR1 RYR3

3.21e-053752CID002750949
Drugflubendiamide

RYR1 RYR3

3.21e-053752CID011193251
DrugRyanodyl 3-(pyridine-3-carboxylate

RYR1 RYR3

3.21e-053752CID005748312
Drug8N3-cADPR

RYR1 RYR3

3.21e-053752CID000127713
DrugN-(2-methyl-3-(4-(4-(4-(trifluoromethoxy)benzyloxy)piperidin-1-yl)-1,3,5-triazin-2-ylamino)phenyl)acetamide

SCN3A SCN9A

3.21e-053752ctd:C561228
Drugaminodantrolene

RYR1 RYR3

3.21e-053752CID009570289
Drugisoflurane

SCN3A SCN9A ALAS1 RYR1 RYR3 DNMT1 GABRA1

3.75e-05279757CID000003763
DrugMethotrexate [59-05-2]; Down 200; 8.8uM; PC3; HG-U133A

DOCK1 ACSL1 PIGK RBL2 ARFGEF2 TRAPPC10

4.25e-051937561957_DN
DrugMethimazole [60-56-0]; Up 200; 35uM; MCF7; HT_HG-U133A

FAM171A1 FRY SCN1A C8B KCNIP1 ITPR2

4.63e-051967564372_UP
DrugCGX 0596987; Up 200; 20uM; MCF7; HT_HG-U133A

TRIO SCN1A SCN5A SCN8A KDM5D TESPA1

4.77e-051977566412_UP
Drug(+) -Levobunolol hydrochloride [47141-41-3]; Up 200; 12.2uM; MCF7; HT_HG-U133A

MKRN3 EBF2 ABCA2 TRIO KCNIP1 FAAH

4.90e-051987564980_UP
DrugNicardipine hydrochloride [54527-84-3]; Up 200; 7.8uM; PC3; HT_HG-U133A

KIF21B WSB1 SCN11A ABCA2 GLS2 SCN8A

4.90e-051987566297_UP
DrugDibucaine [85-79-0]; Up 200; 11.6uM; PC3; HT_HG-U133A

EBF2 FRY ARSD PPP1R16B MVD RYR1

5.04e-051997564068_UP
Drugmibefradil

SCN5A SCN9A RYR1 RYR3

5.94e-0564754CID000060662
Drugbepridil

SCN3A SCN5A SCN9A RYR1 RYR3

6.07e-05126755CID000002351
DrugAC1L1CQC

PDHB SCN3A SCN5A SCN9A

6.31e-0565754CID000002012
DrugA-30

RYR1 RYR3

6.40e-054752CID003028528
DrugLidocaine

SCN5A SCN9A

6.40e-054752DB00281
DrugPCB74

RYR1 RYR3

6.40e-054752CID000036218
Drug148504-47-6

RYR1 RYR3

6.40e-054752CID006444275
DrugBastadin 10

RYR1 RYR3

6.40e-054752CID009589366
DrugAPETx2 protein, Anthopleura elegantissima

SCN2A SCN8A

6.40e-054752ctd:C501880
DrugSC 38249

RYR1 RYR3

6.40e-054752CID000134834
DrugAC1L1U7A

RYR1 RYR3

6.40e-054752CID000035682
Drugbenzilate

SCN9A PHLPP1 ADCY9 OPRD1

6.71e-0566754CID000201538
DrugAC1L1IZE

RBL2 DNAH9 RYR1 RYR3 DNAH1

7.30e-05131755CID000004799
DrugKn 04

RBL2 RYR1 RYR3

8.45e-0526753CID000131117
Drugphenytoin

SCN2A SCN3A SCN5A SCN9A RYR1 RYR3

8.57e-05219756CID000001775
DrugAC1L1MOZ

SCN3A SCN5A SCN9A

9.49e-0527753CID000031958
DrugTopiramate

SCN1A GABRA1

1.06e-045752DB00273
DrugQuinidine barbiturate

SCN5A GABRA1

1.06e-045752DB01346
Drug2,3-dimethylindoline

DROSHA RBL2

1.06e-045752CID000030944
DrugLOPAC

SCN2A RYR1 RYR3

1.31e-0430753CID000062696
Drugtocainide

SCN3A SCN5A SCN9A

1.31e-0430753CID000038945
Drugprocaine

SCN3A SCN9A RYR1 RYR3 GABRA1

1.52e-04153755CID000004914
Drugfenpropathrin

SCN2A SCN3A

1.59e-046752ctd:C044267
DrugMBED

RYR1 RYR3

1.59e-046752CID000129958
Drugchloro-m-cresol

RYR1 RYR3

1.59e-046752CID000012008
DrugAC1O528X

RYR1 RYR3

1.59e-046752CID006475857
DrugNSC114784

RYR1 RYR3

1.59e-046752CID000419425
DrugNSC692750

RYR1 RYR3

1.59e-046752CID000078910
DrugAC1LD8Z3

ABCA2 DNAH9 ADCY9 RYR1

1.88e-0486754CID000644309
DrugAmitriptyline

SCN11A GLS2 RBL2 DNMT1 GABRA1

2.16e-04165755ctd:D000639
DrugAzumoleno

RYR1 RYR3

2.22e-047752CID000056259
Drugmag-indo-1

RYR1 RYR3

2.22e-047752CID000131881
DrugBr2BAPTA

RYR1 RYR3

2.22e-047752CID003081001
Drug[[(2R,3S,4R)-5-(2-amino-6-oxo-3H-purin-9-yl)-3,4-dihydroxyoxolan-2-yl]methoxy-hydroxyphosphoryl] [(2R,3S,4R,5R)-3,4,5-trihydroxyoxolan-2-yl]methyl hydrogen phosphate

RYR1 RYR3

2.22e-047752CID009547999
DrugCHEBI:564108

RYR1 RYR3

2.22e-047752CID006400637
Druggallocyanin

GCA KDM5D

2.22e-047752CID000073801
Drugbenzocaine

SCN2A SCN3A SCN9A

2.46e-0437753CID000002337
Drug1,2-dichlorohexafluorocyclobutane

SCN2A RYR1 RYR3

2.46e-0437753CID000009643
Drug4-chloro-m-cresol

SCN5A RYR1 RYR3

2.46e-0437753CID000001732
Drugsodium

SCN2A SCN3A SCN5A SCN9A CHN1 ADCY9 RYR1 RYR3 OPRD1 DNMT1 GABRA1

2.54e-049447511CID000000923
DrugN-arachidonoyl-dopamine

SCN2A GCA FAAH

2.88e-0439753CID005282105
Drug5-butyl-2-phenoxyphenol

PPIP5K2 OPRD1

2.96e-048752CID005274975
DrugCocaine

SCN11A SCN5A

2.96e-048752DB00907
Drugcarbamazepine

SCN2A SCN3A SCN5A SCN9A ADCY9

3.14e-04179755CID000002554
DrugAC1L1I54

ADCY9 MVD OPRD1

3.34e-0441753CID000004426
Drugisradipine

SCN3A SCN9A RYR1 RYR3

3.35e-04100754CID000003784
Drugisoproterenol

SCN11A GUCY2F AVPR2 SCN3A SCN5A SCN9A ADCY9 RYR1 RYR3

3.45e-04669759CID000003779
DrugMycophenolic acid [24280-93-1]; Up 200; 12.4uM; MCF7; HT_HG-U133A

WSB1 FAM171A1 GLS2 ARSD TRIO

3.66e-041857554137_UP
Druglactosyl lysosphingolipid

RYR1 RYR3

3.80e-049752CID006439268
DrugAC1Q7A0V

PHLPP1 OPRD1

3.80e-049752CID000001250
Drugm-7a

PHLPP1 RYR1

3.80e-049752CID000029558
DrugMexiletine

SCN5A SCN9A

3.80e-049752ctd:D008801
DrugApApA

SCN5A RYR1

3.80e-049752CID000097495
DrugFLA 365

RYR1 RYR3

3.80e-049752CID000072776
DrugGossypol [303-45-7]; Up 200; 7.8uM; PC3; HT_HG-U133A

MKRN3 WSB1 ATP8A1 RBL2 ITPR2

3.93e-041887554296_UP
Drugprocainamide

SCN11A SCN3A SCN5A SCN9A DNMT1

4.13e-04190755CID000004913
DrugIsoconazole [27523-40-6]; Up 200; 9.6uM; HL60; HG-U133A

WSB1 NCOA3 FRY PHLPP1 ALAS1

4.13e-041907551372_UP
Drugpropofol

SCN3A SCN9A RYR1 RYR3 GABRA1

4.23e-04191755CID000004943
Drugbaclofen

ADCY9 RYR1 RYR3 OPRD1 GABRA1

4.23e-04191755CID000002284
Drugphosphine oxide

RBL2 CHN1 RYR1 RYR3

4.34e-04107754CID000166931
DrugFenbufen [36330-85-5]; Up 200; 15.8uM; HL60; HT_HG-U133A

FRY ABCA2 PPP1R16B TRAPPC10 MVD

4.44e-041937552346_UP
DrugTenoxicam [59804-37-4]; Up 200; 11.8uM; MCF7; HT_HG-U133A

FAM171A1 GUCY2F SCN5A SCN8A TESPA1

4.54e-041947554182_UP
DrugCinchonine [118-10-5]; Down 200; 13.6uM; MCF7; HT_HG-U133A

DNAL4 ABCA2 GLS2 ALAS1 MVD

4.54e-041947554107_DN
DrugTrihexyphenidyl-D,L Hydrochloride [58947-95-8]; Up 200; 11.8uM; PC3; HT_HG-U133A

KIF21B WSB1 ABCA2 ATP8A1 TRIO

4.54e-041947554015_UP
Diseasegeneralized epilepsy with febrile seizures plus 2 (implicated_via_orthology)

SCN11A SCN1A SCN2A SCN3A SCN5A SCN8A SCN9A

6.75e-1710767DOID:0111294 (implicated_via_orthology)
DiseaseDravet syndrome (implicated_via_orthology)

SCN11A SCN1A SCN2A SCN3A SCN5A SCN8A SCN9A

6.75e-1710767DOID:0080422 (implicated_via_orthology)
Diseasegeneralized epilepsy with febrile seizures plus (implicated_via_orthology)

SCN11A SCN1A SCN2A SCN3A SCN5A SCN8A SCN9A

4.44e-1612767DOID:0060170 (implicated_via_orthology)
Diseaseepilepsy (implicated_via_orthology)

SCN11A TRIO SCN1A SCN2A SCN3A SCN5A SCN8A SCN9A

1.00e-08163768DOID:1826 (implicated_via_orthology)
DiseaseInfantile Severe Myoclonic Epilepsy

SCN1A SCN2A SCN9A GABRA1

2.85e-0813764C0751122
Diseaseanxiety disorder (implicated_via_orthology)

SCN1A SCN2A SCN3A SCN9A

2.87e-0722764DOID:2030 (implicated_via_orthology)
DiseaseHereditary Sensory Autonomic Neuropathy, Type 5

SCN11A SCN9A DNMT1

5.70e-077763C0020075
DiseaseGeneralized Epilepsy with Febrile Seizures Plus

SCN1A SCN2A SCN9A

1.36e-069763C3502809
DiseaseEarly Infantile Epileptic Encephalopathy 6

SCN1A SCN9A

6.55e-062762C4551549
DiseaseEpilepsy

SCN1A SCN2A SCN8A SCN9A OPRD1

9.40e-06109765C0014544
DiseaseB Virus Infection

SCN8A SCN9A

1.96e-053762C0037140
DiseaseBenign familial infantile epilepsy

SCN2A SCN8A

1.96e-053762cv:C5575231
Diseasecongenital myopathy 1A (implicated_via_orthology)

RYR1 RYR3

1.96e-053762DOID:3529 (implicated_via_orthology)
DiseasePostherpetic neuralgia

SCN8A SCN9A

1.96e-053762C0032768
DiseaseHerpesviridae Infections

SCN8A SCN9A

1.96e-053762C0019372
Diseasemalignant hyperthermia (implicated_via_orthology)

RYR1 RYR3

1.96e-053762DOID:8545 (implicated_via_orthology)
DiseasePAROXYSMAL EXTREME PAIN DISORDER

SCN11A SCN9A

1.96e-053762C1833661
DiseasePrimary Erythermalgia

SCN11A SCN9A

1.96e-053762C0014805
DiseaseEpilepsy, Cryptogenic

SCN1A SCN2A SCN8A OPRD1

6.10e-0582764C0086237
DiseaseAwakening Epilepsy

SCN1A SCN2A SCN8A OPRD1

6.10e-0582764C0751111
DiseaseAura

SCN1A SCN2A SCN8A OPRD1

6.10e-0582764C0236018
DiseaseHereditary Sensory Autonomic Neuropathy, Type 2

SCN9A DNMT1

6.51e-055762C0020072
DiseaseFamilial benign neonatal epilepsy

SCN2A SCN8A

9.75e-056762C0220669
DiseaseSensory Neuropathy, Hereditary

SCN9A DNMT1

9.75e-056762C0699739
DiseaseNeurodevelopmental Disorders

TRIO SCN1A SCN2A SCN8A

9.97e-0593764C1535926
DiseaseSeizure, Febrile, Simple

SCN1A SCN2A

1.36e-047762C0149886
DiseaseSeizure, Febrile, Complex

SCN1A SCN2A

1.36e-047762C0751057
DiseaseCongenital Pain Insensitivity

SCN11A SCN9A

1.36e-047762C0002768
DiseaseN-palmitoylglycine measurement

DMBX1 FAAH

1.36e-047762EFO_0800342
DiseaseEarly Childhood Epilepsy, Myoclonic

SCN1A SCN9A

1.81e-048762C0393695
DiseaseIdiopathic Myoclonic Epilepsy

SCN1A SCN9A

1.81e-048762C0338478
DiseaseSymptomatic Myoclonic Epilepsy

SCN1A SCN9A

1.81e-048762C0338479
DiseaseMyoclonic Encephalopathy

SCN1A SCN9A

1.81e-048762C0438414
DiseaseBenign Infantile Myoclonic Epilepsy

SCN1A SCN9A

1.81e-048762C0751120
DiseaseMyoclonic Absence Epilepsy

SCN1A SCN9A

1.81e-048762C0393703
DiseaseDrug habituation

DOCK1 CTNNA3 FAAH OPRD1

2.26e-04115764C0013170
DiseaseSubstance-Related Disorders

DOCK1 CTNNA3 FAAH OPRD1

2.26e-04115764C0236969
DiseaseDrug abuse

DOCK1 CTNNA3 FAAH OPRD1

2.26e-04115764C0013146
DiseaseDrug Use Disorders

DOCK1 CTNNA3 FAAH OPRD1

2.26e-04115764C0013222
DiseaseDrug Dependence

DOCK1 CTNNA3 FAAH OPRD1

2.26e-04115764C1510472
DiseaseSubstance Dependence

DOCK1 CTNNA3 FAAH OPRD1

2.26e-04115764C0038580
DiseaseSubstance Use Disorders

DOCK1 CTNNA3 FAAH OPRD1

2.26e-04115764C0038586
DiseaseOrganic Mental Disorders, Substance-Induced

DOCK1 CTNNA3 FAAH OPRD1

2.26e-04115764C0029231
DiseasePrescription Drug Abuse

DOCK1 CTNNA3 FAAH OPRD1

2.26e-04115764C4316881
DiseaseFebrile Convulsions

SCN1A SCN2A

2.33e-049762C0009952
DiseaseMyoclonic Epilepsy

SCN1A SCN9A

2.33e-049762C0014550
DiseaseSubstance abuse problem

DOCK1 CTNNA3 FAAH OPRD1

2.34e-04116764C0740858
DiseaseEpilepsy, Myoclonic, Infantile

SCN1A SCN9A

2.91e-0410762C0917800
DiseaseMyoclonic Astatic Epilepsy

SCN1A SCN9A

3.55e-0411762C0393702
Diseaseadverse effect, response to xenobiotic stimulus

ABCA2 GLS2 CTNNA3

4.81e-0459763EFO_0009658, GO_0009410
Diseaseinfant head circumference

ZBTB38 ARFGEF2

6.73e-0415762EFO_0004577
DiseaseMMR-related febrile seizures

SCN1A SCN2A

6.73e-0415762EFO_0006519
DiseaseTremor, Rubral

SCN8A GABRA1

7.67e-0416762C0750940
DiseaseAtaxia, Appendicular

SCN8A GABRA1

7.67e-0416762C0750937
DiseaseAtaxia, Motor

SCN8A GABRA1

7.67e-0416762C0278161
DiseaseAbnormal coordination

SCN8A GABRA1

7.67e-0416762C0520966
DiseaseAtaxia, Truncal

SCN8A GABRA1

7.67e-0416762C0427190
DiseaseAtaxia, Sensory

SCN8A GABRA1

7.67e-0416762C0240991
DiseaseEarly infantile epileptic encephalopathy with suppression bursts

SCN1A SCN2A

7.67e-0416762C0393706
Diseasepartial epilepsy

SCN1A ADCY9

8.68e-0417762EFO_0004263
DiseaseFebrile seizure (within the age range of 3 months to 6 years)

SCN1A SCN2A

9.75e-0418762HP_0002373
Diseasesystemic lupus erythematosus

FAM171A1 NADSYN1 GLS2 TCP11 PDHB CTNNA3 WDFY4 LDB2

1.04e-03799768MONDO_0007915
Diseasepulmonary hypertension (biomarker_via_orthology)

ALAS1 RYR1 RYR3

1.17e-0380763DOID:6432 (biomarker_via_orthology)
DiseaseBRCAX breast cancer

DOCK1 ITPR2

1.21e-0320762EFO_0009443
Diseasebirth weight, parental genotype effect measurement

ZBTB38 ARFGEF2 DNMT1 ITPR2

1.55e-03192764EFO_0004344, EFO_0005939
Diseaseairway responsiveness measurement

TCP11 WDFY4

1.74e-0324762EFO_0006897
DiseaseAtaxia

SCN8A GABRA1

1.89e-0325762C0004134
Diseaseretinal vasculature measurement

EBF2 FRY TRIO CTNNA3 MCM2 DNAH9

2.18e-03517766EFO_0010554
Diseasecardiovascular age measurement

SCN5A CTNNA3

2.54e-0329762EFO_0803380

Protein segments in the cluster

PeptideGeneStartEntry
EMRVRCAIIPSDMLH

BANP

226

Q8N9N5
CILMRNHDVTEQPMV

ARSD

256

P51689
DMSALVAARMRHIPL

DNMT1

1416

P26358
EPRVRLVMAQHMIRD

BAG6

161

P46379
PLAHMFERVVECVML

ACSL1

321

P33121
CAIHARRVTIMPRDM

H3Y2

111

P0DPK5
LETCRIMIAMLDRDH

GCA

91

P28676
SPTIRDMAIRCIAQM

ARFGEF2

1196

Q9Y6D5
NPEMCRVLLTHEVMC

EBF2

146

Q9HAK2
LTMMAVCHTAVPERE

ATP8A1

481

Q9Y2Q0
VISSMPCLLMELRRD

C18orf25

51

Q96B23
SFPILLHMMCSERDR

ITPR2

1351

Q14571
PITVRHIESMIRMAE

MCM2

761

P49736
IIQCPELMMDRHLDQ

RBL2

876

Q08999
VECEVINMRTIRPMD

PDHB

261

P11177
DMPAVMRLACADTRV

OR10V1

181

Q8NGI7
LLDRRPTECMMSRSV

FAM171A1

531

Q5VUB5
PTECMMSRSVDHLER

FAM171A1

536

Q5VUB5
PRMMQDADCHRLLVD

KLHL31

276

Q9H511
MSRHPRVCGAVMDTL

ALAS1

256

P13196
ISSLVQLMMDPHCRT

MTMR12

401

Q9C0I1
RVLLEQMGSLPCAMH

KDM5D

841

Q9BY66
LCVILEPMQELMSRH

LDB2

206

O43679
LVRHSDMPEEMRVET

DNAL4

21

O96015
CAIHARRVTIMPRDM

H3Y1

111

P0DPK2
HFLREMPALIRMACV

OR2W3

176

Q7Z3T1
IHLCQMRMCTQPDLV

KIF21B

231

O75037
SVVPARMAEMARCIR

MVD

231

P53602
MMVHCAGCERPILDR

LHX5

1

Q9H2C1
YTMRLTVRAECPMHL

GABRA1

156

P14867
PRLRDCMSEMHRVVQ

GLS2

106

Q9UI32
HIVLMLADDMACNPR

PIGK

81

Q92643
DELEMTMVCHRPEGL

KCNIP1

36

Q9NZI2
CDSLCIPMVMRHLEQ

MEI1

551

Q5TIA1
MAVTRPRDGAVVCML

OPRD1

186

P41143
RVAPEQQMIADIHCM

PPP1R16B

201

Q96T49
TIHDIRCSVMMIRTP

CTNNA3

616

Q9UI47
RCSVMMIRTPEELED

CTNNA3

621

Q9UI47
HMVLCMSPIGEVFRA

DNAH1

2711

Q9P2D7
DRTEMPCQALVRMLA

CKAP5

631

Q14008
TQHDCREILLPMMTD

DOCK1

851

Q14185
PDVVMRERLAMCTNL

DMBX1

96

Q8NFW5
IHQADRIRIIIMCMH

GUCY2F

236

P51841
RDDFLFVIEHMMPLC

ABCA2

696

Q9BZC7
ERMIHSVMPRIIADD

ADCY9

331

O60503
PSCLHDSMEMLRLED

CEP85L

201

Q5SZL2
CLRFMREVERLMTPE

FAAH

561

O00519
TALQRLCMLRAMRPD

DNAH9

3846

Q9NYC9
PLHRCNIAVIFMTEM

FRY

1636

Q5TBA9
AHTTKRPMVVDMCIR

CHN1

276

P15882
RPMVVDMCIREIESR

CHN1

281

P15882
MALHIPEENRCMDIL

RYR1

1636

P21817
RQMRSVDVTLMPIDC

C8B

51

P07358
GIRSDVCQHAMMLPV

DROSHA

851

Q9NRR4
MITHALERVCSVMPA

PSAPL1

316

Q6NUJ1
NCRMLMKTPHDILED

NCOA3

196

Q9Y6Q9
PMVSGDRIHCMDILF

SCN5A

1841

Q14524
MDLPMVSGDRIHCLD

SCN9A

1826

Q15858
MSRALADVMRPQGHC

SHISA9

186

B4DS77
AMDLPMVSGDRIHCL

SCN3A

1836

Q9NY46
AMDLPMVSGDRIHCL

SCN1A

1851

P35498
MMALLCAPVRDEAVQ

TCP11

166

Q8WWU5
PMDAAQREEHMRACI

MKRN3

276

Q13064
MMALHIPEENRCVDI

RYR3

1531

Q15413
AMDLPMVSGDRIHCL

SCN2A

1841

Q99250
AAIMHPGVVCIMVRL

WDFY4

826

Q6ZS81
AMDLPMVSGDRIHCL

SCN8A

1831

Q9UQD0
LMICQRRSPAMHRTC

UNQ9370/PRO34162

16

Q6UXP9
AAMMAVRVLLDHDVP

UCKL1

461

Q9NWZ5
VMQCSHLVMRPVALD

ZNF687

591

Q8N1G0
PTTIMNCRRMHTVIA

PHLPP1

1076

O60346
DLPMVSEDRLHCMDI

SCN11A

1671

Q9UI33
RRIEMEDPCLMLASR

TESPA1

206

A2RU30
LDRHEQICMRSSHMP

ZBTB38

386

Q8NAP3
TMMELRCVIAVIRHG

PPIP5K2

376

O43314
SLQHLCRMSIRRVMP

WSB1

386

Q9Y6I7
PVAARATHRVHMEVM

TRAPPC10

1136

P48553
MRVPSALVTLHMLLC

VIRMA

1031

Q69YN4
GTMMELRCVIAIIRH

PPIP5K1

386

Q6PFW1
LAMTLDRHRAICRPM

AVPR2

131

P30518
AVEVMCIVPRRCNDM

TRIO

2131

O75962
DIICDVGMPVMHRNV

NADSYN1

81

Q6IA69