Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	protein tyrosine kinase collagen receptor activity	DDR1 DDR2	5.91e-05	2	154	2	GO:0038062
GeneOntologyMolecularFunction	stretch-activated, monoatomic cation-selective, calcium channel activity	TRPV4 NALF2	1.76e-04	3	154	2	GO:0015275
GeneOntologyBiologicalProcess	extracellular matrix disassembly	DDR1 DDR2 LAMC1 MELTF HPN CST1	1.99e-05	75	153	6	GO:0022617
GeneOntologyBiologicalProcess	regulation of extracellular matrix disassembly	DDR1 DDR2 MELTF CST1	3.26e-05	25	153	4	GO:0010715
Domain	C8	ZAN SSPOP BMPER MUC6	1.93e-06	12	151	4	PF08742
Domain	TIL	ZAN SSPOP BMPER MUC6	1.93e-06	12	151	4	PF01826
Domain	Unchr_dom_Cys-rich	ZAN SSPOP BMPER MUC6	2.77e-06	13	151	4	IPR014853
Domain	C8	ZAN SSPOP BMPER MUC6	2.77e-06	13	151	4	SM00832
Domain	TIL_dom	ZAN SSPOP BMPER MUC6	3.86e-06	14	151	4	IPR002919
Domain	VWF_type-D	ZAN SSPOP BMPER MUC6	6.93e-06	16	151	4	IPR001846
Domain	VWFD	ZAN SSPOP BMPER MUC6	6.93e-06	16	151	4	PS51233
Domain	VWD	ZAN SSPOP BMPER MUC6	6.93e-06	16	151	4	SM00216
Domain	VWD	ZAN SSPOP BMPER MUC6	6.93e-06	16	151	4	PF00094
Domain	CXorf40	EOLA1 EOLA2	6.49e-05	2	151	2	IPR033615
Domain	DDR1/DDR2	DDR1 DDR2	6.49e-05	2	151	2	IPR029553
Domain	UPF0028	PNPLA6 PNPLA7	6.49e-05	2	151	2	PS01237
Domain	ZnF_GATA	GATA1 GATA6 ZGLP1	1.08e-04	12	151	3	SM00401
Domain	ASCH_domain	EOLA1 EOLA2	1.94e-04	3	151	2	IPR007374
Domain	Transferrin	MELTF LTF	1.94e-04	3	151	2	PF00405
Domain	Transferrin	MELTF LTF	1.94e-04	3	151	2	IPR016357
Domain	TRANSFERRIN_LIKE_4	MELTF LTF	1.94e-04	3	151	2	PS51408
Domain	ASCH	EOLA1 EOLA2	1.94e-04	3	151	2	SM01022
Domain	TRANSFERRIN_LIKE_1	MELTF LTF	1.94e-04	3	151	2	PS00205
Domain	TRANSFERRIN_LIKE_2	MELTF LTF	1.94e-04	3	151	2	PS00206
Domain	TRANSFERRIN_LIKE_3	MELTF LTF	1.94e-04	3	151	2	PS00207
Domain	Transferrin_Fe_BS	MELTF LTF	1.94e-04	3	151	2	IPR018195
Domain	TR_FER	MELTF LTF	1.94e-04	3	151	2	SM00094
Domain	Transferrin-like_dom	MELTF LTF	1.94e-04	3	151	2	IPR001156
Domain	Znf_GATA	GATA1 GATA6 ZGLP1	2.19e-04	15	151	3	IPR000679
Domain	GATA	GATA1 GATA6 ZGLP1	2.19e-04	15	151	3	PF00320
Domain	IBN_N	TNPO1 TNPO2 RANBP17	2.19e-04	15	151	3	PF03810
Domain	GATA_ZN_FINGER_1	GATA1 GATA6 ZGLP1	2.69e-04	16	151	3	PS00344
Domain	IBN_N	TNPO1 TNPO2 RANBP17	2.69e-04	16	151	3	SM00913
Domain	GATA_ZN_FINGER_2	GATA1 GATA6 ZGLP1	2.69e-04	16	151	3	PS50114
Domain	Importin-beta_N	TNPO1 TNPO2 RANBP17	3.24e-04	17	151	3	IPR001494
Domain	VWF_dom	ZAN SSPOP BMPER MUC6	3.62e-04	42	151	4	IPR001007
Domain	VWC_out	ZAN SSPOP MUC6	4.56e-04	19	151	3	SM00215
Domain	FA58C	DDR1 DDR2 SSPOP	6.19e-04	21	151	3	SM00231
Domain	FA58C_3	DDR1 DDR2 SSPOP	6.19e-04	21	151	3	PS50022
Domain	FA58C_1	DDR1 DDR2 SSPOP	6.19e-04	21	151	3	PS01285
Domain	FA58C_2	DDR1 DDR2 SSPOP	6.19e-04	21	151	3	PS01286
Domain	PAN_AP	HGF MST1L	6.39e-04	5	151	2	SM00473
Domain	RCC1/BLIP-II	TECPR2 HERC1 HERC5	8.15e-04	23	151	3	IPR009091
Domain	Ig_I-set	ROBO4 FLT4 IGFN1 CILP OPCML LRIG2 CILP2	9.09e-04	190	151	7	IPR013098
Domain	I-set	ROBO4 FLT4 IGFN1 CILP OPCML LRIG2 CILP2	9.09e-04	190	151	7	PF07679
Domain	F5_F8_type_C	DDR1 DDR2 SSPOP	9.26e-04	24	151	3	PF00754
Domain	FA58C	DDR1 DDR2 SSPOP	9.26e-04	24	151	3	IPR000421
Domain	WxxW_domain	CILP CILP2	9.53e-04	6	151	2	IPR025155
Domain	Mucin2_WxxW	CILP CILP2	9.53e-04	6	151	2	PF13330
Domain	-	ROBO4 FLT4 IGFN1 CILP ITGB4 OPCML IFNLR1 LRIG2 CILP2 SEMA3B ASTN2 CD79B CD200R1L IL2RB	9.89e-04	663	151	14	2.60.40.10
Domain	Pan_app	HGF MST1L	1.33e-03	7	151	2	IPR003609
Domain	PAN	HGF MST1L	1.33e-03	7	151	2	PS50948
Domain	PAN_1	HGF MST1L	1.33e-03	7	151	2	PF00024
Domain	TSP_1	CILP ADAMTS3 SSPOP CILP2	1.69e-03	63	151	4	PF00090
Domain	Ig-like_fold	ROBO4 FLT4 IGFN1 CILP ITGB4 OPCML IFNLR1 LRIG2 CILP2 SEMA3B ASTN2 CD79B CD200R1L IL2RB	1.79e-03	706	151	14	IPR013783
Domain	TSP1	CILP ADAMTS3 SSPOP CILP2	1.90e-03	65	151	4	SM00209
Domain	TSP1_rpt	CILP ADAMTS3 SSPOP CILP2	1.90e-03	65	151	4	IPR000884
Domain	TSP1	CILP ADAMTS3 SSPOP CILP2	1.90e-03	65	151	4	PS50092
Domain	Patatin	PNPLA6 PNPLA7	2.25e-03	9	151	2	PF01734
Domain	PNPLA	PNPLA6 PNPLA7	2.25e-03	9	151	2	PS51635
Domain	Patatin/PLipase_A2-rel	PNPLA6 PNPLA7	2.25e-03	9	151	2	IPR002641
Domain	DAGK_acc	DGKD DGKI	2.80e-03	10	151	2	PF00609
Domain	Diacylglycerol_kin_accessory	DGKD DGKI	2.80e-03	10	151	2	IPR000756
Domain	DAGKa	DGKD DGKI	2.80e-03	10	151	2	SM00045
Domain	-	DDR1 DDR2 LAMC1 SSPOP	2.90e-03	73	151	4	2.60.120.260
Domain	VWFC_1	ZAN SSPOP BMPER	3.04e-03	36	151	3	PS01208
Domain	IGc2	ROBO4 FLT4 IGFN1 CILP OPCML LRIG2 CILP2	3.05e-03	235	151	7	SM00408
Domain	Ig_sub2	ROBO4 FLT4 IGFN1 CILP OPCML LRIG2 CILP2	3.05e-03	235	151	7	IPR003598
Domain	MACPF	PRF1 ASTN2	3.40e-03	11	151	2	PF01823
Domain	Tyr_kinase_rcpt_2_CS	DDR1 DDR2	3.40e-03	11	151	2	IPR002011
Domain	VWFC_2	ZAN SSPOP BMPER	3.55e-03	38	151	3	PS50184
Domain	VWC	ZAN SSPOP BMPER	3.55e-03	38	151	3	SM00214
Domain	MACPF	PRF1 ASTN2	4.06e-03	12	151	2	IPR020864
Domain	MACPF	PRF1 ASTN2	4.06e-03	12	151	2	SM00457
Domain	RECEPTOR_TYR_KIN_II	DDR1 DDR2	4.06e-03	12	151	2	PS00239
Domain	EGF_1	ZAN LAMC1 SSPOP ITGB4 PRF1 ASTN2 NAGPA	4.76e-03	255	151	7	PS00022
Domain	IMPORTIN_B_NT	TNPO1 TNPO2	5.54e-03	14	151	2	PS50166
Domain	uDENN	DENND2A DENND5A	5.54e-03	14	151	2	SM00800
Domain	DAGKc	DGKD DGKI	5.54e-03	14	151	2	SM00046
Domain	FN3	ROBO4 IGFN1 ITGB4 IFNLR1 ASTN2 IL2RB	5.64e-03	199	151	6	PS50853
Domain	EGF_2	ZAN LAMC1 SSPOP ITGB4 PRF1 ASTN2 NAGPA	5.85e-03	265	151	7	PS01186
Domain	Diacylglycerol_kinase_cat_dom	DGKD DGKI	6.36e-03	15	151	2	IPR001206
Domain	DAGK	DGKD DGKI	6.36e-03	15	151	2	PS50146
Domain	uDENN	DENND2A DENND5A	6.36e-03	15	151	2	PF03456
Domain	DAGK_cat	DGKD DGKI	6.36e-03	15	151	2	PF00781
Domain	IG_LIKE	ROBO4 FLT4 IGFN1 CILP OPCML LRIG2 CILP2 SEMA3B CD79B CD200R1L	6.68e-03	491	151	10	PS50835
Domain	FN3_dom	ROBO4 IGFN1 ITGB4 IFNLR1 ASTN2 IL2RB	7.12e-03	209	151	6	IPR003961
Domain	Galactose-bd-like	DDR1 DDR2 LAMC1 SSPOP	7.13e-03	94	151	4	IPR008979
Domain	DENN	DENND2A DENND5A	7.23e-03	16	151	2	SM00799
Domain	DENN	DENND2A DENND5A	7.23e-03	16	151	2	PF02141
Domain	dDENN	DENND2A DENND5A	7.23e-03	16	151	2	PF03455
Domain	UDENN	DENND2A DENND5A	7.23e-03	16	151	2	PS50946
Domain	DDENN	DENND2A DENND5A	7.23e-03	16	151	2	PS50947
Domain	dDENN	DENND2A DENND5A	7.23e-03	16	151	2	SM00801
Domain	dDENN_dom	DENND2A DENND5A	7.23e-03	16	151	2	IPR005112
Domain	uDENN_dom	DENND2A DENND5A	7.23e-03	16	151	2	IPR005113
Domain	DENN	DENND2A DENND5A	7.23e-03	16	151	2	PS50211
Domain	DENN_dom	DENND2A DENND5A	7.23e-03	16	151	2	IPR001194
Domain	IG	ROBO4 FLT4 IGFN1 CILP OPCML LRIG2 CILP2 SEMA3B CD79B	7.33e-03	421	151	9	SM00409
Domain	Ig_sub	ROBO4 FLT4 IGFN1 CILP OPCML LRIG2 CILP2 SEMA3B CD79B	7.33e-03	421	151	9	IPR003599
Domain	Ig-like_dom	ROBO4 FLT4 IGFN1 CILP OPCML LRIG2 CILP2 SEMA3B CD79B CD200R1L	7.85e-03	503	151	10	IPR007110
Domain	PROTEIN_KINASE_TYR	DDR1 FLT4 DDR2 PRAG1	7.96e-03	97	151	4	PS00109
Domain	Tyr_kinase_AS	DDR1 FLT4 DDR2 PRAG1	7.96e-03	97	151	4	IPR008266
Pubmed	Nucleotide sequence of the partially deleted D4Z4 locus in a patient with FSHD identifies a putative gene within each 3.3 kb element.	DUX4L9 DUX4L2 DUX4 DUX4L5 DUX4L6 DUX4L3 DUX4L4 DUX4L7	8.19e-17	12	160	8	10433963
Pubmed	Evolutionary conservation of a coding function for D4Z4, the tandem DNA repeat mutated in facioscapulohumeral muscular dystrophy.	DUX4L9 DUX4L2 DUX4 DUX4L5 DUX4L6 DUX4L3 DUX4L4 DUX4L7	2.12e-16	13	160	8	17668377
Pubmed	The DUX4 gene at the FSHD1A locus encodes a pro-apoptotic protein.	DUX4L2 DUX4 DUX4L5 DUX4L6 DUX4L3 DUX4L4 DUX4L7	3.04e-16	8	160	7	17588759
Pubmed	DUX4, a candidate gene of facioscapulohumeral muscular dystrophy, encodes a transcriptional activator of PITX1.	DUX4L2 DUX4 DUX4L5 DUX4L6 DUX4L3 DUX4L4 DUX4L7	4.53e-15	10	160	7	17984056
Pubmed	Characterization of a tandemly repeated 3.3-kb KpnI unit in the facioscapulohumeral muscular dystrophy (FSHD) gene region on chromosome 4q35.	DUX4L2 DUX4 DUX4L5 DUX4L6 DUX4L3 DUX4L4 DUX4L7	6.41e-14	13	160	7	7739628
Pubmed	Active genes in junk DNA? Characterization of DUX genes embedded within 3.3 kb repeated elements.	DUX4L2 DUX4 DUX4L5 DUX4L6 DUX4L3 DUX4L4 DUX4L7	7.15e-13	17	160	7	11245978
Pubmed	Genome-wide CRISPR screen identifies HNRNPL as a prostate cancer dependency regulating RNA splicing.	DDR1 MAPKAPK2 CEP192 SSPOP AHDC1 ITPKB ZNF331 PLEKHG4B RANBP17 NCOR2 PNPLA6 RDH11 TECPR2 ATXN2 PROM2 MICAL2 HPN TBCK SEMA3B UBA6 ASTN2 LSM14A ATP11A PNPLA7 DENND5A ZSWIM4	4.97e-09	1489	160	26	28611215
Pubmed	A dual-activity topoisomerase complex regulates mRNA translation and turnover.	DAB2IP MAPKAPK2 AKNA CARD10 CEP192 ECE1 PRAG1 ITGB4 AHDC1 IFNLR1 PLEKHH3 SLC52A3 NCOR2 MDN1 PNPLA6 ZNF592 PROM2 EIF2B3 KBTBD11 DENND5A HERC1	4.23e-08	1105	160	21	35748872
Pubmed	Expression profiling of immature thymocytes revealed a novel homeobox gene that regulates double-negative thymocyte development.	DUX4L9 DUX4L2 DUX4L4	3.81e-07	4	160	3	17911620
Pubmed	The homeobox transcription factor DUXBL controls exit from totipotency.	DUX4L9 DUX4L2 DUX4L4	3.81e-07	4	160	3	38509386
Pubmed	Characterization of genomic structures and expression profiles of three tandem repeats of a mouse double homeobox gene: Duxbl.	DUX4L9 DUX4L2 DUX4L4	9.49e-07	5	160	3	20063414
Pubmed	GPAT2 is required for piRNA biogenesis, transposon silencing, and maintenance of spermatogonia in mice†.	PIWIL4 TDRD1 GPAT2	3.30e-06	7	160	3	30951587
Pubmed	The transcription factor Duxbl mediates elimination of pre-T cells that fail β-selection.	DUX4L9 DUX4L2 DUX4L4	3.30e-06	7	160	3	30765463
Pubmed	Novel splice variants derived from the receptor tyrosine kinase superfamily are potential therapeutics for rheumatoid arthritis.	HGF DDR1 FLT4 VEGFD	8.10e-06	28	160	4	18593464
Pubmed	Loss of neuropathy target esterase in mice links organophosphate exposure to hyperactivity.	PNPLA6 PNPLA7	2.10e-05	2	160	2	12640454
Pubmed	Discoidin domain receptor inhibition reduces neuropathology and attenuates inflammation in neurodegeneration models.	DDR1 DDR2	2.10e-05	2	160	2	28863860
Pubmed	Discoidin domain receptor 2 is involved in the activation of bone marrow-derived dendritic cells caused by type I collagen.	DDR1 DDR2	2.10e-05	2	160	2	17113033
Pubmed	Ca2+ entry via alpha1G and TRPV4 channels differentially regulates surface expression of P-selectin and barrier integrity in pulmonary capillary endothelium.	TRPV4 CACNA1G	2.10e-05	2	160	2	19617313
Pubmed	Vascular endothelial growth factor-D activates VEGFR-3 expressed in osteoblasts inducing their differentiation.	FLT4 VEGFD	2.10e-05	2	160	2	16624815
Pubmed	Expression of CILP-2 and DDR2 and ultrastructural changes in the articular cartilage of patients with knee osteoarthritis undergoing total knee arthroplasty: a pilot morphological study.	DDR2 CILP2	2.10e-05	2	160	2	36370214
Pubmed	Inhibition of collagen fibrillogenesis by cells expressing soluble extracellular domains of DDR1 and DDR2.	DDR1 DDR2	2.10e-05	2	160	2	19900459
Pubmed	Discoidin domain receptors: a promoter of the aggressive behavior of ameloblastomas.	DDR1 DDR2	2.10e-05	2	160	2	24723326
Pubmed	Defective regulation of microRNA target genes in myoblasts from facioscapulohumeral dystrophy patients.	DUX4L9 DUX4	2.10e-05	2	160	2	24145033
Pubmed	Cartilage intermediate layer protein 2 (CILP-2) is expressed in articular and meniscal cartilage and down-regulated in experimental osteoarthritis.	CILP CILP2	2.10e-05	2	160	2	21880736
Pubmed	Hepsin activates pro-hepatocyte growth factor and is inhibited by hepatocyte growth factor activator inhibitor-1B (HAI-1B) and HAI-2.	HGF HPN	2.10e-05	2	160	2	15792801
Pubmed	VEGFR-3/Flt-4 mediates proliferation and chemotaxis in glial precursor cells.	FLT4 VEGFD	2.10e-05	2	160	2	19646499
Pubmed	Discoidin domain receptors in disease.	DDR1 DDR2	2.10e-05	2	160	2	24361528
Pubmed	An extracellular matrix-specific microarray allowed the identification of target genes downstream of discoidin domain receptors.	DDR1 DDR2	2.10e-05	2	160	2	12935821
Pubmed	Expression and mutation analysis of the discoidin domain receptors 1 and 2 in non-small cell lung carcinoma.	DDR1 DDR2	2.10e-05	2	160	2	17299390
Pubmed	Vascular endothelial growth factor receptor-3 is a novel target to improve net ultrafiltration in methylglyoxal-induced peritoneal injury.	FLT4 VEGFD	2.10e-05	2	160	2	26121315
Pubmed	Transportin-mediated nuclear import of heterogeneous nuclear RNP proteins.	TNPO1 TNPO2	2.10e-05	2	160	2	9298975
Pubmed	Complex roles of discoidin domain receptor tyrosine kinases in cancer.	DDR1 DDR2	2.10e-05	2	160	2	33634432
Pubmed	Mapping of the NEP receptor tyrosine kinase gene to human chromosome 6p21.3 and mouse chromosome 17C.	DDR1 DDR2	2.10e-05	2	160	2	7774938
Pubmed	Low stability and a conserved N-glycosylation site are associated with regulation of the discoidin domain receptor family by glucose via post-translational N-glycosylation.	DDR1 DDR2	2.10e-05	2	160	2	24018687
Pubmed	Clustering, Spatial Distribution, and Phosphorylation of Discoidin Domain Receptors 1 and 2 in Response to Soluble Collagen I.	DDR1 DDR2	2.10e-05	2	160	2	30458172
Pubmed	Comparison of (18)F-fluorodeoxyglucose PET/CT findings with vascular endothelial growth factors and receptors in colorectal cancer.	FLT4 VEGFD	2.10e-05	2	160	2	26476536
Pubmed	Scatter factor/hepatocyte growth factor as a regulator of skeletal muscle and neural crest development.	HGF TYRP1	2.10e-05	2	160	2	8650184
Pubmed	Identification of an insulin-regulated lysophospholipase with homology to neuropathy target esterase.	PNPLA6 PNPLA7	2.10e-05	2	160	2	18086666
Pubmed	VEGF-D promotes tumor growth and lymphatic spread in a mouse model of hepatocellular carcinoma.	FLT4 VEGFD	2.10e-05	2	160	2	18338756
Pubmed	Transportin-1 and Transportin-2: protein nuclear import and beyond.	TNPO1 TNPO2	2.10e-05	2	160	2	24780099
Pubmed	Discoidin Domain Receptors, DDR1b and DDR2, Promote Tumour Growth within Collagen but DDR1b Suppresses Experimental Lung Metastasis in HT1080 Xenografts.	DDR1 DDR2	2.10e-05	2	160	2	32047176
Pubmed	Recombinant Collagen Engineered to Bind to Discoidin Domain Receptor Functions as a Receptor Inhibitor.	DDR1 DDR2	2.10e-05	2	160	2	26702058
Pubmed	Role of discoidin domain receptors 1 and 2 in human smooth muscle cell-mediated collagen remodeling: potential implications in atherosclerosis and lymphangioleiomyomatosis.	DDR1 DDR2	2.10e-05	2	160	2	15111304
Pubmed	DDR1 and DDR2 physical interaction leads to signaling interconnection but with possible distinct functions.	DDR1 DDR2	2.10e-05	2	160	2	29616590
Pubmed	Tyrosine kinase discoidin domain receptors DDR1 and DDR2 are coordinately deregulated in triple-negative breast cancer.	DDR1 DDR2	2.10e-05	2	160	2	25667101
Pubmed	Serum level of VEGF-D in patients with primary lymphedema.	FLT4 VEGFD	2.10e-05	2	160	2	15693535
Pubmed	Increased expression of discoidin domain receptor 2 (DDR2): a novel independent prognostic marker of worse outcome in breast cancer patients.	DDR1 DDR2	2.10e-05	2	160	2	23307244
Pubmed	Defective Ca(2+) binding in a conserved binding site causes incomplete N-glycan processing and endoplasmic reticulum trapping of discoidin domain receptors.	DDR1 DDR2	2.10e-05	2	160	2	25470979
Pubmed	Discoidin domain receptor (DDR) 1 and 2: collagen-activated tyrosine kinase receptors in the cornea.	DDR1 DDR2	2.10e-05	2	160	2	11133186
Pubmed	VEGF-D promotes pulmonary oedema in hyperoxic acute lung injury.	FLT4 VEGFD	2.10e-05	2	160	2	26924464
Pubmed	Mutations in MINAR2 encoding membrane integral NOTCH2-associated receptor 2 cause deafness in humans and mice.	DUX4L9 DUX4L2 DUX4L4	4.17e-05	15	160	3	35727972
Pubmed	Proteomic analysis identifies transcriptional cofactors and homeobox transcription factors as TBX18 binding proteins.	DUX4L9 DUX4L2 DUX4L4	4.17e-05	15	160	3	30071041
Pubmed	Semi-automatic classification of skeletal morphology in genetically altered mice using flat-panel volume computed tomography.	DDR1 DDR2	6.29e-05	3	160	2	17658952
Pubmed	The discoidin domain receptor DDR2 is a receptor for type X collagen.	DDR1 DDR2	6.29e-05	3	160	2	16806867
Pubmed	High interstitial fluid pressure promotes tumor progression through inducing lymphatic metastasis-related protein expressions in oral squamous cell carcinoma.	FLT4 VEGFD	6.29e-05	3	160	2	24085575
Pubmed	A glycine-rich domain of hnRNP H/F promotes nucleocytoplasmic shuttling and nuclear import through an interaction with transportin 1.	TNPO1 HNRNPH1	6.29e-05	3	160	2	20308327
Pubmed	Vascular endothelial growth factor (VEGF)-C, VEGF-D, VEGFR-3 and D2-40 expressions in primary breast cancer: Association with lymph node metastasis.	FLT4 VEGFD	6.29e-05	3	160	2	28791841
Pubmed	The specificity of receptor binding by vascular endothelial growth factor-d is different in mouse and man.	FLT4 VEGFD	6.29e-05	3	160	2	11279005
Pubmed	CD5 is associated with the human B cell antigen receptor complex.	CD5 CD79B	6.29e-05	3	160	2	7512031
Pubmed	Lymphangiogenesis and its relationship with lymphatic metastasis and prognosis in malignant melanoma.	FLT4 VEGFD	6.29e-05	3	160	2	18561194
Pubmed	The role of the VEGF-C/-D/flt-4 autocrine loop in the pathogenesis of salivary neoplasms.	FLT4 VEGFD	6.29e-05	3	160	2	22326635
Pubmed	Effects of acute exercise, exercise training, and diabetes on the expression of lymphangiogenic growth factors and lymphatic vessels in skeletal muscle.	FLT4 VEGFD	6.29e-05	3	160	2	17766486
Pubmed	Vascular endothelial growth factor D is dispensable for development of the lymphatic system.	FLT4 VEGFD	6.29e-05	3	160	2	15743836
Pubmed	Soluble vascular endothelial growth factor receptor-3 suppresses lymphangiogenesis and lymphatic metastasis in bladder cancer.	FLT4 VEGFD	6.29e-05	3	160	2	21481239
Pubmed	Interferon-gamma prevents death of bystander neurons during CD8 T cell responses in the brain.	GATA1 PRF1	6.29e-05	3	160	2	19359516
Pubmed	DeepCAGE transcriptomics identify HOXD10 as a transcription factor regulating lymphatic endothelial responses to VEGF-C.	FLT4 HOXD10	6.29e-05	3	160	2	27199372
Pubmed	Multiple forms of mouse vascular endothelial growth factor-D are generated by RNA splicing and proteolysis.	FLT4 VEGFD	6.29e-05	3	160	2	11574540
Pubmed	Vascular endothelial growth factor D (VEGF-D) is a ligand for the tyrosine kinases VEGF receptor 2 (Flk1) and VEGF receptor 3 (Flt4).	FLT4 VEGFD	6.29e-05	3	160	2	9435229
Pubmed	Human senataxin resolves RNA/DNA hybrids formed at transcriptional pause sites to promote Xrn2-dependent termination.	SETX RNASEH1	6.29e-05	3	160	2	21700224
Pubmed	Role of the VEGFR3/VEGFD receptor axis in TGFbeta1 activation of primary prostate cell lines.	FLT4 VEGFD	6.29e-05	3	160	2	19301310
Pubmed	Senataxin mutations elicit motor neuron degeneration phenotypes and yield TDP-43 mislocalization in ALS4 mice and human patients.	SETX HNRNPH1	6.29e-05	3	160	2	29725819
Pubmed	Expression of VEGF-C, VEGF-D and their receptor VEGFR-3 in diffuse large B-cell lymphomas.	FLT4 VEGFD	6.29e-05	3	160	2	17926187
Pubmed	ALS-associated fused in sarcoma (FUS) mutations disrupt Transportin-mediated nuclear import.	TNPO1 TNPO2	6.29e-05	3	160	2	20606625
Pubmed	Involvement of transportin 2-mediated HuR import in muscle cell differentiation.	TNPO1 TNPO2	6.29e-05	3	160	2	17475777
Pubmed	DUX is a non-essential synchronizer of zygotic genome activation.	PRAMEF5 DUX4L9 DUX4L2 DUX4L4	8.42e-05	50	160	4	31806660
Pubmed	Pro-prion, as a membrane adaptor protein for E3 ligase c-Cbl, facilitates the ubiquitination of IGF-1R, promoting melanoma metastasis.	TNPO1 MAPKAPK2 LAMC1 CARD10 HNRNPH1 PLEKHH3 MELTF MDN1 INTS15 DGKI NKTR FTO	8.91e-05	689	160	12	36543142
Pubmed	Quantitative trait loci for body size components in mice.	DDR1 CAPN10 TYRP1 BMPR1A ZNF592	9.31e-05	98	160	5	16783635
Pubmed	The nucleoporin Nup98 is a site for GDP/GTP exchange on ran and termination of karyopherin beta 2-mediated nuclear import.	TNPO1 TNPO2	1.25e-04	4	160	2	10875935
Pubmed	Development and plasticity of meningeal lymphatic vessels.	FLT4 VEGFD	1.25e-04	4	160	2	29141865
Pubmed	DDR1 regulates the stabilization of cell surface E-cadherin and E-cadherin-mediated cell aggregation.	DDR1 DDR2	1.25e-04	4	160	2	20432435
Pubmed	MTA1 Is Up-regulated in Colorectal Cancer and Is Inversely Correlated with Lymphatic Metastasis.	FLT4 VEGFD	1.25e-04	4	160	2	26543080
Pubmed	Histone modifications silence the GATA transcription factor genes in ovarian cancer.	GATA1 GATA6	1.25e-04	4	160	2	16607277
Pubmed	Interleukin-8: A potent promoter of human lymphatic endothelial cell growth in gastric cancer.	FLT4 VEGFD	1.25e-04	4	160	2	25891418
Pubmed	Tumor-reactive CD4(+) T cells develop cytotoxic activity and eradicate large established melanoma after transfer into lymphopenic hosts.	TYRP1 PRF1	1.25e-04	4	160	2	20156971
Pubmed	LMCD1/Dyxin is a novel transcriptional cofactor that restricts GATA6 function by inhibiting DNA binding.	GATA1 GATA6	1.25e-04	4	160	2	16199866
Pubmed	One of two chondrocyte-expressed isoforms of cartilage intermediate-layer protein functions as an insulin-like growth factor 1 antagonist.	CILP CILP2	1.25e-04	4	160	2	12746903
Pubmed	Karyopherin beta 2B participates in mRNA export from the nucleus.	TNPO1 TNPO2	1.25e-04	4	160	2	12384575
Pubmed	DUX4c is up-regulated in FSHD. It induces the MYF5 protein and human myoblast proliferation.	DUX4L9 DUX4	1.25e-04	4	160	2	19829708
Pubmed	IGFBP7 functions as a potential lymphangiogenesis inducer in non-small cell lung carcinoma.	FLT4 VEGFD	1.25e-04	4	160	2	26706909
Pubmed	One year in review: the pathogenesis of rheumatoid arthritis.	IL2RB IL27	1.25e-04	4	160	2	26203933
Pubmed	130 kb of DNA sequence reveals two new genes and a regional duplication distal to the human iduronate-2-sulfate sulfatase locus.	EOLA1 EOLA2	1.25e-04	4	160	2	8717057
Pubmed	Polymorphisms in the human high sulfur hair keratin-associated protein 1, KAP1, gene family.	KRTAP1-1 KRTAP1-3	1.25e-04	4	160	2	12228244
Pubmed	Pericellular activation of hepatocyte growth factor by the transmembrane serine proteases matriptase and hepsin, but not by the membrane-associated protease uPA.	HGF HPN	1.25e-04	4	160	2	20015050
Pubmed	Critical role of S1PR1 and integrin β4 in HGF/c-Met-mediated increases in vascular integrity.	HGF ITGB4	1.25e-04	4	160	2	23212923
Pubmed	Deregulated hepsin protease activity confers oncogenicity by concomitantly augmenting HGF/MET signalling and disrupting epithelial cohesion.	HGF HPN	1.25e-04	4	160	2	26165838
Pubmed	Transportins 1 and 2 are redundant nuclear import factors for hnRNP A1 and HuR.	TNPO1 TNPO2	1.25e-04	4	160	2	15037768
Pubmed	Integrin α6β4 Promotes Autocrine Epidermal Growth Factor Receptor (EGFR) Signaling to Stimulate Migration and Invasion toward Hepatocyte Growth Factor (HGF).	HGF ITGB4	1.25e-04	4	160	2	26381405
Pubmed	Expression of laminin and nidogen genes during the postimplantation development of the mouse placenta.	LAMC1 TYRP1	2.08e-04	5	160	2	8286607
Pubmed	Regulatory T Cells Restrain Interleukin-2- and Blimp-1-Dependent Acquisition of Cytotoxic Function by CD4+ T Cells.	TYRP1 PRF1	2.08e-04	5	160	2	31924474
Pubmed	HGF and MET mutations in primary and secondary lymphedema.	HGF FLT4	2.08e-04	5	160	2	18564920
Cytoband	Ensembl 112 genes in cytogenetic band chr4q35	TRAPPC11 DUX4L9 DUX4L2 DUX4 DUX4L5 DUX4L6 DUX4L3 DUX4L4 DUX4L7	3.62e-10	117	160	9	chr4q35
Cytoband	4q35.2	DUX4L2 DUX4L5 DUX4L6 DUX4L3 DUX4L4 DUX4L7	4.54e-10	27	160	6	4q35.2
Cytoband	8p11.1	ANK1 HGSNAT	7.21e-05	4	160	2	8p11.1
GeneFamily	PRD class homeoboxes and pseudogenes	DUX4L9 DUX4L2 DUX4L5 DUX4L6 DUX4L3 DUX4L4 DUX4L7	1.46e-06	92	110	7	521
GeneFamily	GATA zinc finger domain containing\|Myb/SANT domain containing	GATA1 GATA6 ZGLP1	9.45e-05	15	110	3	82
GeneFamily	Transferrins	MELTF LTF	1.10e-04	3	110	2	908
GeneFamily	Patatin like phospholipase domain containing	PNPLA6 PNPLA7	1.60e-03	10	110	2	466
GeneFamily	EF-hand domain containing\|Diacylglycerol kinases	DGKD DGKI	1.60e-03	10	110	2	1178
GeneFamily	Receptor Tyrosine Kinases\|CD molecules	DDR1 FLT4 DDR2	1.84e-03	40	110	3	321
GeneFamily	Blood group antigens\|CD molecules\|I-set domain containing\|Immunoglobulin like domain containing	ROBO4 FLT4 IGFN1 OPCML LRIG2	3.04e-03	161	110	5	593
Coexpression	GSE22886_NAIVE_CD4_TCELL_VS_48H_ACT_TH1_UP	SNPH SETX DGKD MSL1 ECE1 TESPA1 CD5 NKTR IKBKB NAGPA	4.01e-07	200	158	10	M4524
Coexpression	GSE22886_NAIVE_CD4_TCELL_VS_12H_ACT_TH1_UP	DENND2A SETX ABCC5 CEP68 ASTN2 LSM14A NKTR DENND5A HERC1	3.54e-06	199	158	9	M4521
Coexpression	GSE22886_CD8_VS_CD4_NAIVE_TCELL_DN	DENND2A ANK1 ECE1 CD5 SEMA3B ATP11A NKTR DENND5A	2.62e-05	196	158	8	M4404
Coexpression	GSE32423_MEMORY_VS_NAIVE_CD8_TCELL_IL7_UP	PPIL4 SLC52A3 BMPR1A RNFT2 ZNF592 ATP11A PNPLA7 CD200R1L	3.03e-05	200	158	8	M5074
Coexpression	GSE22886_NAIVE_BCELL_VS_BLOOD_PLASMA_CELL_UP	DDR1 HGSNAT ABCC5 FAM131A ITPKB LRIG2 CEP68 KLHL3	3.03e-05	200	158	8	M4440
Coexpression	DESCARTES_FETAL_CEREBELLUM_VASCULAR_ENDOTHELIAL_CELLS	ROBO4 FLT4 C2CD4B LAMC1 CARD10 ECE1 TDRD1 MYCBPAP SLC52A3 MELTF XIRP2 EXOC3L1 CD79B LTF	3.84e-05	645	158	14	M40158
ToppCell	Endothelial-B-SSc-ILD_02\|World / lung cells shred on cell class, cell subclass, sample id	ROBO4 FLT4 C2CD4B ARHGAP23 OPCML KLHL3 HOXD10 KBTBD11	1.88e-07	176	154	8	b288116a4588a1f9db9d49af92cea118937c9201
ToppCell	LV-14._Fibroblast_III\|World / Chamber and Cluster_Paper	SLC19A2 ECE1 ZNF331 JARID2 NCOR2 MELTF CACNA1G BMPER	3.23e-07	189	154	8	3922135d1f6fc768d71ba3b465585fead6ea68a8
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Mesenchymal-Fibroblast-Collagen-low_Matrisome-low_fibroblast-\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	HGF SGIP1 DDR2 LAMC1 NOL10 MDN1 MICAL2 DENND5A	3.36e-07	190	154	8	1121eb607a984c59fbffe7220837fc178745aa55
ToppCell	Children_(3_yrs)-Endothelial-endothelial_cell_of_lymph_vessel-D032\|Children_(3_yrs) / Lineage, Cell type, age group and donor	ROBO4 DENND2A FLT4 LAMC1 ITGB4 HOXD10 KBTBD11 EXOC3L1	3.36e-07	190	154	8	6e6ce6dd549d1c38cfef5b3f8be06ab01ce344b7
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Mesenchymal-Fibroblast-Collagen-low_Matrisome-low_fibroblast\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	HGF SGIP1 DDR2 LAMC1 NOL10 MDN1 MICAL2 DENND5A	3.36e-07	190	154	8	048b581e3f7ea9fc2f87c0532974bba85c7292c2
ToppCell	Tracheal-NucSeq-Endothelial-Endothelia_lymphatic-Endothelia_Lymphatic\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	ROBO4 DENND2A FLT4 SGIP1 CARD10 KLHL3 HOXD10 KBTBD11	4.26e-07	196	154	8	09a7edf4a7defb7fe70d9777dd9500ee8421ff31
ToppCell	Tracheal-NucSeq-Endothelial-Endothelia_lymphatic\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	ROBO4 DENND2A FLT4 SGIP1 CARD10 KLHL3 HOXD10 KBTBD11	4.26e-07	196	154	8	e50d2c66d5c5cd25fdfecdcc4c8506a1d0a85755
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Mesenchymal-Fibroblast\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	HGF SGIP1 GATA6 LAMC1 NOL10 MDN1 MICAL2 DENND5A	4.60e-07	198	154	8	a860246bcea847249a78fd2e86ed8e04371060db
ToppCell	Tracheal-10x5prime-Endothelial-Endothelia_lymphatic\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	ROBO4 DENND2A FLT4 CARD10 SSPOP HOXD10 KBTBD11 EXOC3L1	4.60e-07	198	154	8	05429f18e1d74880c1835568c86177f661b3477a
ToppCell	Tracheal-10x5prime-Endothelial-Endothelia_lymphatic-Endothelia_Lymphatic\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	ROBO4 DENND2A FLT4 CARD10 SSPOP HOXD10 KBTBD11 EXOC3L1	4.60e-07	198	154	8	306e28d31fd587409a12dcccc6b2abd7dc9c2e0a
ToppCell	368C-Myeloid-Monocyte-CD16+_Monocyte\|368C / Donor, Lineage, Cell class and subclass (all cells)	TNPO2 CEP192 IFNLR1 P2RY11 HPN RNASEH1 ZSWIM4	1.22e-06	156	154	7	25b0936960be4955b6a6d6b8a867fdd4be548f05
ToppCell	facs-Trachea-3m-Hematologic-myeloid-granulocyte-granulocyte_l26\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	HGF GATA1 TESPA1 SLC52A3 OPTN ZGLP1 DGKI	1.77e-06	165	154	7	23955e3373660f827518e723ac62fba99753f375
ToppCell	facs-Limb_Muscle-forelimb_and_hindlimb-18m-Lymphocytic-T_cell\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	AKNA CD5 KBTBD11 FAM199X IKBKB NAGPA IL2RB	2.00e-06	168	154	7	182f08106ac65ea501e2fb9139d3b44b7c4662c9
ToppCell	facs-Lung-EPCAM-3m-Lymphocytic\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GATA1 TESPA1 CD5 PRF1 CD79B CD200R1L IL2RB	2.00e-06	168	154	7	68ef5d1043fca804032669bf990edf110d65cf63
ToppCell	368C-Myeloid-Monocyte-CD16+_Monocyte\|Monocyte / Donor, Lineage, Cell class and subclass (all cells)	TNPO2 IFNLR1 HPN NKTR RNASEH1 ZSWIM4 TLCD3A	2.16e-06	170	154	7	4a19c7e3bb0f9c2601a10debe7000066789b4150
ToppCell	droplet-Liver-HEPATOCYTES-1m-Lymphocytic-NK/T\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	AKNA PRAG1 TESPA1 PRF1 KBTBD11 CD200R1L IL2RB	2.25e-06	171	154	7	2e7cc311005958af52f39ca6c310c85b43a85aaf
ToppCell	droplet-Liver-HEPATOCYTES-1m-Lymphocytic-NK_cell\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	AKNA PRAG1 TESPA1 PRF1 KBTBD11 CD200R1L IL2RB	2.25e-06	171	154	7	4b599f953c8e5b947b2c8bbbf7fe6f9dc388e336
ToppCell	Adult-Endothelial-endothelial_cell_of_lymph_vessel-D122\|Adult / Lineage, Cell type, age group and donor	ROBO4 DENND2A FLT4 SGIP1 CARD10 CEP68 KLHL3	2.43e-06	173	154	7	dba09ba9748871e38a16449d500ae4d7b405c42f
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic-thymocyte\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	IGFN1 ANK1 ZAN SSPOP MELTF XIRP2 ONECUT3	3.65e-06	184	154	7	2cbed6462fea2622871bb7e49b0df3d984239281
ToppCell	(6)_Endothelial-F_(Lymphatics)\|World / Lung cell shreds - cell class (v4) and cell subclass (v4)	ROBO4 FLT4 ARHGAP23 CARD10 KLHL3 KBTBD11 EXOC3L1	3.65e-06	184	154	7	03ea613e00b45c81b752c14505a0538d698f551e
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	IGFN1 ANK1 ZAN SSPOP MELTF XIRP2 ONECUT3	3.65e-06	184	154	7	ea7a7e2bac46d4d2c31a5d576b38a032b5335062
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic-proliferating_thymocyte;_DN_to_DP_transition,_dividing_(some_are_Cd8+/_Cd4+,_some_undergoing_VDJ_recombination)\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	IGFN1 ANK1 ZAN SSPOP MELTF XIRP2 ONECUT3	3.65e-06	184	154	7	2b19a8c5f823e00812908b23e66bb4e563278aff
ToppCell	Control-Endothelial-Endothelial-Activated_Gen_Cap\|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	C2CD4B ARHGAP23 CARD10 EXOC3L1 LTF RELT	4.05e-06	121	154	6	a5962d1c476e6966870832b72d511607e047248b
ToppCell	Children_(3_yrs)-Endothelial-endothelial_cell_of_lymph_vessel\|Children_(3_yrs) / Lineage, Cell type, age group and donor	ROBO4 DENND2A FLT4 SGIP1 CARD10 KLHL3 KBTBD11	4.21e-06	188	154	7	c2805232618a7b6f844d34e37ad458a9923dbfe1
ToppCell	390C-Endothelial_cells-Endothelial-F_(Lymphatics)\|390C / Donor, Lineage, Cell class and subclass (all cells)	ROBO4 DENND2A FLT4 ARHGAP23 CARD10 KBTBD11 EXOC3L1	4.21e-06	188	154	7	aa69e3f44d506f5ef358a3374ac5160d847c858f
ToppCell	390C-Endothelial_cells-Endothelial-F_(Lymphatics)-\|390C / Donor, Lineage, Cell class and subclass (all cells)	ROBO4 DENND2A FLT4 ARHGAP23 CARD10 KBTBD11 EXOC3L1	4.21e-06	188	154	7	1f40b959777d18ad88d239df8cca304f062ba04c
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell-Distal_Convoluted_Tubule_Cell_Type_1\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	DENND2A SGIP1 ABCC5 KCTD1 ITPKB KLHL3 HOXD10	4.36e-06	189	154	7	975c0f079903ae36b0ffa54e86294d42ec7697de
ToppCell	COVID-19-Heart-CM_4\|Heart / Disease (COVID-19 only), tissue and cell type	MAPKAPK2 ABCC5 DGKD STRIP2 TECPR2 ATP11A MAPK4	4.51e-06	190	154	7	3729648a17093b438398b82e32bbccc3af7b8c5d
ToppCell	wk_08-11-Endothelial-Lymph_endothelial\|wk_08-11 / Celltypes from embryonic and fetal-stage human lung	ROBO4 FLT4 CARD10 HOXD10 MICAL2 KBTBD11 EXOC3L1	4.51e-06	190	154	7	d7f1dc032d161529559e01832d1a3112c6f6cc1a
ToppCell	ASK440-Epithelial-Secretory\|ASK440 / Donor, Lineage and Cell class of Lung cells from Dropseq	DDR1 ARHGAP23 ABCC5 PLEKHG4B PROM2 SEMA3B LTF	5.00e-06	193	154	7	50e98d91697c7af6a3de39e52edde6dd2b67b512
ToppCell	LPS-IL1RA+antiTNF-Stromal_mesenchymal-Matrix_Fibroblast-MatrixFB\|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	HGF DENND2A ADAMTS3 DDR2 ASTN2 BMPER VEGFD	5.00e-06	193	154	7	fb28717fadd06c3840636d25409ce80c9254bd34
ToppCell	kidney_cells-Adult_normal_reference-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell-Degenerative_Distal_Convoluted_Tubule_Cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	DENND2A ITPKB KLHL3 HOXD10 PROM2 HPN MST1L	5.00e-06	193	154	7	dd9874898587fe9fd9cf2aebc2e0579dcf06944e
ToppCell	15-Airway-Endothelial\|Airway / Age, Tissue, Lineage and Cell class	ROBO4 FLT4 C2CD4B CARD10 ECE1 ITGB4 EXOC3L1	5.17e-06	194	154	7	ac0e48b0c09a7f57d30dff321b0c30a4c5e16ad9
ToppCell	15-Airway-Endothelial-Endothelial\|Airway / Age, Tissue, Lineage and Cell class	ROBO4 FLT4 C2CD4B CARD10 ECE1 ITGB4 EXOC3L1	5.17e-06	194	154	7	f3851337a2d17f4acef2cd812a766eb0b503748b
ToppCell	kidney_cells-Adult_normal_reference-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	DENND2A ITPKB KLHL3 HOXD10 PROM2 HPN MST1L	5.17e-06	194	154	7	f08a7618a9ccf12e4a7620235ae662a8abc521af
ToppCell	COVID_non-vent-Lymphocytic\|COVID_non-vent / Disease condition, Lineage, Cell class and subclass	TESPA1 HNRNPH1 OPTN CD5 PRF1 NKTR IL2RB	5.72e-06	197	154	7	c672915f8c8c1e948d251f6eaf9f84a5600c1193
ToppCell	10x_3'_v2v3-Non-neoplastic-Endothelial-Endothelial_mature-Endo_arterial-G\|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	ROBO4 FLT4 C2CD4B LAMC1 ECE1 RANBP17 VEGFD	5.72e-06	197	154	7	a312d9cf4ced949307eb9620be4eed926300b892
ToppCell	390C-Endothelial_cells\|390C / Donor, Lineage, Cell class and subclass (all cells)	ROBO4 FLT4 C2CD4B ARHGAP23 CARD10 ECE1 EXOC3L1	5.72e-06	197	154	7	aa381acea0f7882d39435a6f713386bf0588b5f8
ToppCell	Bronchial-NucSeq-Endothelial-Endothelia_lymphatic-Endothelia_Lymphatic\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	ROBO4 DENND2A FLT4 SGIP1 KLHL3 HOXD10 KBTBD11	5.91e-06	198	154	7	b3a020522e064bb61949d38e442f24026e339364
ToppCell	Bronchial-NucSeq-Endothelial-Endothelia_lymphatic\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	ROBO4 DENND2A FLT4 SGIP1 KLHL3 HOXD10 KBTBD11	5.91e-06	198	154	7	fc4b7c3ad52bc5c8b40fa04a156bfbb58afa2872
ToppCell	10x_3'_v2v3-Non-neoplastic-Endothelial-Endothelial_mature-Endo_arterial\|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	ROBO4 FLT4 C2CD4B ECE1 TDRD1 SLC52A3 EXOC3L1	6.11e-06	199	154	7	0602e2b2aa56d106da63bd342a38bef437b4d496
ToppCell	10x_3'_v2v3-Non-neoplastic-Endothelial-Endothelial_mature-Endo_arterial-F\|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	ROBO4 FLT4 C2CD4B LAMC1 ECE1 SLC52A3 EXOC3L1	6.11e-06	199	154	7	463ba77dc4c85eebb343f29a42c7ac889b0497c9
ToppCell	kidney_cells-Renal_AKI_(acute_kidney_injury)-Epithelial-Collecting_tubule_epithelial_cell-kidney_connecting_tubule_epithelial_cell-Connecting_Tubule_Cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	DDR1 ADAMTS3 ABCC5 SLC52A3 KLHL3 HOXD10 TRPV4	6.11e-06	199	154	7	3cd6383c50ce342fe5c175e2e50784d634a90e80
ToppCell	Neuronal-Excitatory-eA(LAMP5_LINC00507)-FREM3---L2-3\|Neuronal / cells hierarchy compared to all cells using T-Statistic	PDE4C ADAMTS3 KCTD1 PRAG1 TESPA1 STRIP2 MAPK4	6.31e-06	200	154	7	9c89e91bb630cc306a820927a36ea6fb3d13e9d7
ToppCell	Lung_Parenchyma-Control-Endothelial-Endothelial-Lymphatic-\|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	ROBO4 FLT4 ARHGAP23 CARD10 CEP68 KLHL3 KBTBD11	6.31e-06	200	154	7	f99d0d3f51b4893fa7898c5b435494358a654cbd
ToppCell	Lung_Parenchyma-Control-Endothelial-Endothelial-Lymphatic\|Control / Location, Disease Group, Cell group, Cell class (2021.03.09)	ROBO4 FLT4 ARHGAP23 CARD10 CEP68 KLHL3 KBTBD11	6.31e-06	200	154	7	e65d4ae3d48f68c12edd5dc2c2f4e25e4acfadf1
ToppCell	Parenchyma_Control_(B.)-Endothelial-TX-Lymphatic\|Parenchyma_Control_(B.) / Sample group, Lineage and Cell type	ROBO4 FLT4 ARHGAP23 CARD10 CEP68 KLHL3 KBTBD11	6.31e-06	200	154	7	4ec8e30dd241d83a1bba1c5967b6a4656afbfafd
ToppCell	Neuronal-Excitatory-eA(LAMP5_LINC00507)-FREM3-\|Neuronal / cells hierarchy compared to all cells using T-Statistic	PDE4C ADAMTS3 KCTD1 PRAG1 TESPA1 STRIP2 MAPK4	6.31e-06	200	154	7	8821574d17b55dfea3ca0204e6b4c0ca6b19588a
ToppCell	Neuronal-Excitatory-eA(LAMP5_LINC00507)-FREM3--\|Neuronal / cells hierarchy compared to all cells using T-Statistic	PDE4C ADAMTS3 KCTD1 PRAG1 TESPA1 STRIP2 MAPK4	6.31e-06	200	154	7	96b1d2e70fbbba744fd4356a70efcf356aca9abc
ToppCell	Neuronal-Excitatory-eA(LAMP5_LINC00507)-FREM3\|Neuronal / cells hierarchy compared to all cells using T-Statistic	PDE4C ADAMTS3 KCTD1 PRAG1 TESPA1 STRIP2 MAPK4	6.31e-06	200	154	7	ad6f1d4d7f5d7bab2ba2e4fff58c535290065c0e
ToppCell	facs-Marrow-B-cells-24m-Lymphocytic-NK_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TDRD1 SSPOP PRF1 LRRTM2 DGKI IL2RB	9.38e-06	140	154	6	7ca49bd7ba9381e75c10f888775df17e5d46804d
ToppCell	facs-Marrow-B-cells-24m-Lymphocytic-NK_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TDRD1 SSPOP PRF1 LRRTM2 DGKI IL2RB	9.38e-06	140	154	6	1a31bc33d5723b9bc528cc0047ca5f4c80531c7a
ToppCell	facs-Marrow-Granulocytes-18m-Hematologic-megakaryocyte-erythroid_progenitor_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DENND2A ANK1 TNPO2 TECPR2 TRPV4 CACNA1G	2.00e-05	160	154	6	56e6f4b82b5dc41c45f9d253c2db314a6f702b84
ToppCell	facs-Marrow-Granulocytes-18m-Hematologic-megakaryocyte-erythroid_progenitor_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DENND2A ANK1 TNPO2 TECPR2 TRPV4 CACNA1G	2.00e-05	160	154	6	bb1b966fb9e801db15e67d03e49db4609d6f935a
ToppCell	367C-Lymphocytic-ILC-ILC-3\|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)	NPM2 TECPR2 ASTN2 RELT MIEF2 IL27	2.07e-05	161	154	6	8de421c61f4d5a6e05fdb20e4d230e2db98ee4d5
ToppCell	3'-GW_trimst-1-LargeIntestine-Mesenchymal-fibroblastic-Stromal_3_(KCNN3+)\|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	CEP295NL PRAG1 LIN37 ZGLP1 XIRP2 CHRNA10	2.30e-05	164	154	6	d167c7a987b9b35d1e7725c803df4f9cd5380e47
ToppCell	Endothelial-B-Donor_01\|World / lung cells shred on cell class, cell subclass, sample id	ROBO4 DENND2A FLT4 CARD10 HOXD10 KBTBD11	2.38e-05	165	154	6	b6893882472aeb0d18e26f47eaec9d53688afcde
ToppCell	Endothelial-B-IPF_01\|World / lung cells shred on cell class, cell subclass, sample id	ROBO4 DENND2A FLT4 CARD10 SSPOP KLHL3	2.46e-05	166	154	6	c286987ea4e511195607c87ec4529c2c2ed2122e
ToppCell	E16.5-Endothelial-Endothelial_lymphatic\|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	FLT4 INSL5 FAM131A ECE1 CD5 KBTBD11	2.55e-05	167	154	6	b93103a868fba63a8910bffb690a6242b9252833
ToppCell	368C-Myeloid-Monocyte-CD16+_Monocyte\|Myeloid / Donor, Lineage, Cell class and subclass (all cells)	TNPO2 IFNLR1 HPN RNASEH1 ZSWIM4 TLCD3A	2.55e-05	167	154	6	dbd2b9f2f4ba7be5fdf8318094e6b078cb1d1c43
ToppCell	E16.5-Endothelial-Endothelial_lymphatic-Lymphatic_EC-LEC\|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	FLT4 INSL5 FAM131A ECE1 CD5 KBTBD11	2.55e-05	167	154	6	fcd583b1efd0ac883379982ea8e6c54f2c0be268
ToppCell	E16.5-Endothelial-Endothelial_lymphatic-Lymphatic_EC\|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	FLT4 INSL5 FAM131A ECE1 CD5 KBTBD11	2.55e-05	167	154	6	f6bc63138b7239211fa5f27a8dc799b6e022c0f8
ToppCell	wk_15-18-Hematologic-Myeloid-HSC\|wk_15-18 / Celltypes from embryonic and fetal-stage human lung	ZAN GALR3 GATA1 TESPA1 NPM2 XIRP2	2.55e-05	167	154	6	5f793eafbb593317caa9afd8267e561e09058ddb
ToppCell	E16.5-Endothelial-Endothelial_lymphatic-Lymphatic_EC-LEC-LEC_mature\|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	FLT4 INSL5 FAM131A ECE1 CD5 KBTBD11	2.55e-05	167	154	6	26cd8ee5e826e71eaf58d10a906543a6932fb3f9
ToppCell	Endothelial-B-Cryobiopsy_01\|World / lung cells shred on cell class, cell subclass, sample id	ROBO4 DENND2A FLT4 SGIP1 KLHL3 HOXD10	2.73e-05	169	154	6	95c617143e1fbdd1d55a93ffdcc210e0be37cf2f
ToppCell	droplet-Liver-HEPATOCYTES-1m-Lymphocytic\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	AKNA PRAG1 PRF1 KBTBD11 CD200R1L IL2RB	2.73e-05	169	154	6	d721dbb317a88113b4f76688111908d00f23e899
ToppCell	10x_3'_v3-tissue-resident_(10x_3'_v3)-hematologic-erythrocytic-erythroid_lineage_cell\|tissue-resident_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type	ANK1 TYRP1 MICAL2 CST1 LTF MAPK4	2.82e-05	170	154	6	288014dedda8babc51fe08e48a55e68d83e1b1d2
ToppCell	Basal_cells-SSc-ILD_02\|World / lung cells shred on cell class, cell subclass, sample id	C2CD4B ITGB4 PLEKHG4B TRPV4 BMPER MAPK4	2.82e-05	170	154	6	776d4224a682b6c648041827efd69794f88906f0
ToppCell	droplet-Liver-LIVER_NPC-30m-Lymphocytic\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	AKNA TESPA1 CD5 PRF1 CD79B IL2RB	2.82e-05	170	154	6	26178277bf9c7f2f06b5c0b03d4b69d78e9580c4
ToppCell	facs-Marrow-T-cells-3m-Hematologic-MPP_Fraction_B_+_C\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ADAMTS3 GALR3 PLEKHH3 RANBP17 RNFT2 TRPV4	2.82e-05	170	154	6	d70aaa0f4e5034bb9f61b832b5f9123870936d3c
ToppCell	facs-Lung-Endomucin-3m-Endothelial-Lymphatic_endothelial_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FLT4 KCTD1 PRAG1 NPM2 LRIG2 RANBP17	3.01e-05	172	154	6	b3c4adccc34bb9e4e78e40f4e2e23736c347cc75
ToppCell	AT1-AT2_cells-Cryobiopsy_01\|World / lung cells shred on cell class, cell subclass, sample id	ECE1 ITGB4 PLEKHH3 PROM2 SEMA3B MUC6	3.01e-05	172	154	6	0be41df5d35d818deb7316ac21c9366eb4b7bfd1
ToppCell	Bronchial_Biopsy-Endothelial-Lymphatic\|Bronchial_Biopsy / Tissue, Lineage and Cell class of Lung Cells from 10X	ROBO4 FLT4 SGIP1 SSPOP KBTBD11 HERC5	3.01e-05	172	154	6	c41f5a66781bbf63afce7ca5d118cc6d8e0fe0bc
ToppCell	Endothelial-B-Donor_06\|World / lung cells shred on cell class, cell subclass, sample id	ROBO4 DENND2A FLT4 C2CD4B SGIP1 VEGFD	3.01e-05	172	154	6	8a527dff06d841a86c7eb04a1dd9630787294da4
ToppCell	facs-Lung-Endomucin-3m-Endothelial-endothelial_cell_of_lymphatic_vessel\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FLT4 KCTD1 PRAG1 NPM2 LRIG2 RANBP17	3.01e-05	172	154	6	2f1673fcb2356684d60871debb0f159aec553a1c
ToppCell	facs-SCAT-Fat-24m-Lymphocytic-CD8-positive,_alpha-beta_T_cell\|SCAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	AKNA ITPKB CILP2 PRF1 KBTBD11 IL2RB	3.21e-05	174	154	6	87fa5deff5c1aabb342d674f05ad17c4c0e50d01
ToppCell	-IPF_02\|World / lung cells shred on cell class, cell subclass, sample id	GATA1 TESPA1 CD5 PRF1 CD79B IL2RB	3.21e-05	174	154	6	ba50cc04fcdee1926d4af4787ac86555ae9632cc
ToppCell	11.5-Distal-Immune-Hematopoietic,_B_Cells\|Distal / Age, Tissue, Lineage and Cell class	ANK1 GATA1 TESPA1 DGKI CD79B CHRNA10	3.31e-05	175	154	6	d8ca8fbe5309dab293c335b32f1b138edfdd0b07
ToppCell	facs-Heart-RA-3m-Lymphocytic-T_cell\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GATA1 AKNA TESPA1 CD5 KBTBD11 IL2RB	3.31e-05	175	154	6	db977f18a71845ecb16ee3e6b3fb03dea4a1a8bc
ToppCell	facs-Heart-RA-3m-Lymphocytic-T_cell\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GATA1 AKNA TESPA1 CD5 KBTBD11 IL2RB	3.31e-05	175	154	6	7b38cbd73be26cf33393c6e6c804d62856a91ec3
ToppCell	primary_auditory_cortex_(A1C)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_D_(IT_RORB_THEMIS_LINC00507)_3-Exc_L2-3_LINC00507_RPL9P17\|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	PDE4C ADAMTS3 KCTD1 PRAG1 TESPA1 MAPK4	3.42e-05	176	154	6	07abf29d681abdd6c7cc87f9eaf9377e92ce212c
ToppCell	Control-Neuronal_cells-Neuronal_cells\|Control / group, cell type (main and fine annotations)	ROBO4 DENND2A FLT4 SGIP1 OPCML KLHL3	3.42e-05	176	154	6	98c07d26ba0dc0fe15ca0ea81f633d4591782bd1
ToppCell	Somatosensory_Cortex_(S1)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_D_(IT_RORB_THEMIS_LINC00507)_3-Exc_L2-3_LINC00507_RPL9P17\|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	PDE4C ADAMTS3 KCTD1 PRAG1 TESPA1 MAPK4	3.42e-05	176	154	6	c7be4eaa5eb76ad9389fb9d15ad0934e88d267d1
ToppCell	Control-Neuronal_cells\|Control / group, cell type (main and fine annotations)	ROBO4 DENND2A FLT4 SGIP1 OPCML KLHL3	3.42e-05	176	154	6	c29d09ecf0eb17f767d78af4b7f2e7725c967ff8
ToppCell	Somatosensory_Cortex_(S1)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_D_(IT_RORB_THEMIS_LINC00507)_3\|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	PDE4C ADAMTS3 KCTD1 PRAG1 TESPA1 MAPK4	3.53e-05	177	154	6	8b003ed7887479c3a010ef37dd981b748256bda7
ToppCell	droplet-Marrow-BM-30m-Hematologic-nan\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ANK1 ARHGAP23 GATA1 CD5 KBTBD11 IL2RB	3.53e-05	177	154	6	650095a17e1a39caea74a6e89646565b9332af5d
ToppCell	droplet-Marrow-BM-30m-Hematologic\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ANK1 ARHGAP23 GATA1 CD5 KBTBD11 IL2RB	3.53e-05	177	154	6	d1af0cb4b1fb03f04cff5add85e29be8fb8f4dcb
ToppCell	primary_auditory_cortex_(A1C)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_D_(IT_RORB_THEMIS_LINC00507)_3\|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	PDE4C ADAMTS3 KCTD1 PRAG1 TESPA1 MAPK4	3.65e-05	178	154	6	5d6297f34e104bacefb25c4e2338b50fe13dd19a
ToppCell	3'-Parenchyma_lung-Endothelial-Lymphatic_EC-endothelial_cell_of_lymphatic_vessel-Lymphatic_EC_differentiating-Lymphatic_EC_differentiating_L.2.5.1.1\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	ROBO4 DENND2A FLT4 CEP68 KLHL3 KBTBD11	3.65e-05	178	154	6	ad3de3e03a401dac64431a541899445262246347
ToppCell	facs-Heart-RA-3m-Lymphocytic\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GATA1 AKNA TESPA1 CD5 KBTBD11 IL2RB	3.65e-05	178	154	6	ba6ded4455233635a11afcf6f522c786bd81b5e0
ToppCell	5'-GW_trimst-1.5-LargeIntestine-Endothelial-lymphatic_endothelial\|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	ROBO4 FLT4 KLHL3 MICAL2 KBTBD11 EXOC3L1	3.76e-05	179	154	6	abc6797bd3884aa75dca58fcb2523ee321243ab1
ToppCell	5'-GW_trimst-1.5-LargeIntestine-Endothelial-lymphatic_endothelial-LEC4_(STAB2+)\|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	ROBO4 FLT4 KLHL3 MICAL2 KBTBD11 EXOC3L1	3.76e-05	179	154	6	0b996d6e881f31e6b80d359f7caac70ecdeb9982
ToppCell	facs-Diaphragm-Limb_Muscle-3m-Lymphocytic-T_cell\|Diaphragm / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TESPA1 ITPKB CD5 PRF1 KBTBD11 IL2RB	3.76e-05	179	154	6	8bf04a7ad1b0be6722ebfdceba3f083f07bf96c5
ToppCell	367C-Endothelial_cells-Endothelial-F_(Lymphatics)-\|367C / Donor, Lineage, Cell class and subclass (all cells)	ROBO4 FLT4 CARD10 ITGB4 KBTBD11 EXOC3L1	4.00e-05	181	154	6	b244ecaa442bbef51289d8ec574ef08fa9e96318
ToppCell	367C-Endothelial_cells-Endothelial-F_(Lymphatics)\|367C / Donor, Lineage, Cell class and subclass (all cells)	ROBO4 FLT4 CARD10 ITGB4 KBTBD11 EXOC3L1	4.00e-05	181	154	6	dd79de8098edb385a0f85d0e9621503cdf76ec43
ToppCell	COVID-19-Heart-CM_4\|COVID-19 / Disease (COVID-19 only), tissue and cell type	ABCC5 DGKD STRIP2 XIRP2 TECPR2 MAPK4	4.25e-05	183	154	6	2902b6e8aa9a6f62bc1a792c971ab7f651a8e676
ToppCell	Mid-temporal_gyrus_(MTG)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_D_(IT_RORB_THEMIS_LINC00507)_3-Exc_L2-3_LINC00507_RPL9P17\|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	PDE4C ADAMTS3 KCTD1 PRAG1 TESPA1 MAPK4	4.25e-05	183	154	6	1645d4a55cd8c22d6eb47fc5c6b1e576c454f111
ToppCell	droplet-Fat-BAT+GAT+MAT-30m-Lymphocytic-lymphocyte\|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TESPA1 OPTN CD5 KBTBD11 CD79B IL2RB	4.25e-05	183	154	6	a305667cfdae50e64e1890f10f71b407ae617b80
ToppCell	Fetal_29-31_weeks-Endothelial-endothelial_cell_of_lymph_vessel-D088\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	FLT4 ARHGAP23 CARD10 ITGB4 HOXD10 KBTBD11	4.25e-05	183	154	6	bc98df870de65aff6dab295c24cbc199c7f2aa15
ToppCell	Mid-temporal_gyrus_(MTG)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_D_(IT_RORB_THEMIS_LINC00507)_3\|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	PDE4C ADAMTS3 KCTD1 PRAG1 TESPA1 MAPK4	4.39e-05	184	154	6	34e316ad8e7b8667cd8ad61397281802a252744f
Disease	intellectual developmental disorder with hypotonia, impaired speech, and dysmorphic facies (implicated_via_orthology)	TNPO1 TNPO2	2.37e-05	2	144	2	DOID:0081262 (implicated_via_orthology)
Disease	Charcot-Marie-Tooth Disease	SETX HOXD10 TRPV4	2.42e-05	12	144	3	C0007959
Disease	Autosomal Recessive Hereditary Spastic Paraplegia	PNPLA6 TECPR2	1.41e-04	4	144	2	C0751603
Disease	X-Linked, Spastic Paraplegia, Hereditary	PNPLA6 TECPR2	1.41e-04	4	144	2	C0751605
Disease	Hereditary X-Linked Recessive Spastic Paraplegia	PNPLA6 TECPR2	1.41e-04	4	144	2	C0751604
Disease	von Willebrand factor measurement	DAB2IP C2CD4B CARD10 GTF3C5	1.64e-04	56	144	4	EFO_0004629
Disease	Amyotrophic Lateral Sclerosis	SETX ARHGEF28 OPTN ATXN2	1.88e-04	58	144	4	C0002736
Disease	Hereditary Autosomal Dominant Spastic Paraplegia	PNPLA6 TECPR2	2.34e-04	5	144	2	C0751602
Disease	HMSN Type V	PNPLA6 TECPR2	2.34e-04	5	144	2	C4721916
Disease	heart failure	SGIP1 KLHL3 ATXN2 ZNF592 FTO HEATR5B	3.05e-04	185	144	6	EFO_0003144
Disease	acute kidney failure (implicated_via_orthology)	CYP27B1 ECE1 SLC22A2	3.06e-04	27	144	3	DOID:3021 (implicated_via_orthology)
Disease	osteoarthritis (is_implicated_in)	CILP DDR2 NCOR2	3.41e-04	28	144	3	DOID:8398 (is_implicated_in)
Disease	myelofibrosis (implicated_via_orthology)	GATA1 NCOR2	3.50e-04	6	144	2	DOID:4971 (implicated_via_orthology)
Disease	Lymphoma, Non-Hodgkin	PRF1 CD79B IKBKB	5.09e-04	32	144	3	C0024305
Disease	clear cell renal cell carcinoma (is_marker_for)	DDR1 GATA1 FTO	5.58e-04	33	144	3	DOID:4467 (is_marker_for)
Disease	Hereditary Motor and Sensory Neuropathy Type I	HOXD10 TRPV4	6.50e-04	8	144	2	C0751036
Disease	cerebellar ataxia (implicated_via_orthology)	PNPLA6 PNPLA7	6.50e-04	8	144	2	DOID:0050753 (implicated_via_orthology)
Disease	Roussy-Levy Syndrome (disorder)	HOXD10 TRPV4	6.50e-04	8	144	2	C0205713
Disease	blindness (implicated_via_orthology)	PNPLA6 PNPLA7	6.50e-04	8	144	2	DOID:1432 (implicated_via_orthology)
Disease	Charcot-Marie-Tooth Disease, Type Ib	HOXD10 TRPV4	6.50e-04	8	144	2	C0270912
Disease	Charcot-Marie-Tooth Disease, Type Ia (disorder)	HOXD10 TRPV4	6.50e-04	8	144	2	C0270911
Disease	nevus count, cutaneous melanoma	JARID2 TYRP1 ATP11A FTO	1.05e-03	91	144	4	EFO_0000389, EFO_0004632
Disease	aspartate aminotransferase to alanine aminotransferase ratio	PDE4C AKNA JARID2 CILP2 ATXN2 FTO	1.17e-03	239	144	6	EFO_0010934
Disease	QT interval	SGIP1 ARHGEF28 SLC19A2 LAMC1 DGKD KCTD1 HNRNPH1 NPM2 ZNF592	1.28e-03	534	144	9	EFO_0004682
Disease	anthropometric measurement	GDF5-AS1 ADAMTS3 ATXN2 ASTN2 FTO	1.43e-03	168	144	5	EFO_0004302
Disease	Secondary Open Angle Glaucoma	OPTN ATXN2	1.51e-03	12	144	2	C0271148
Disease	thyroid gland carcinoma (is_marker_for)	ROBO4 FLT4	1.51e-03	12	144	2	DOID:3963 (is_marker_for)
Disease	Glaucoma, Open-Angle	OPTN ATXN2	1.51e-03	12	144	2	C0017612
Disease	bilirubin measurement	TNPO1 ANK1 DGKD MELTF CILP2 ATXN2 ASTN2 IL27	1.52e-03	442	144	8	EFO_0004570
Disease	Glaucoma, Primary Open Angle	OPTN ATXN2	1.78e-03	13	144	2	C0339573
Disease	Hereditary Motor and Sensory-Neuropathy Type II	HOXD10 TRPV4	1.78e-03	13	144	2	C0270914
Disease	coffee consumption measurement	OPCML RANBP17 NCOR2 CD5 FTO	2.04e-03	182	144	5	EFO_0006781
Disease	Spastic Paraplegia, Hereditary	PNPLA6 TECPR2	2.07e-03	14	144	2	C0037773
Disease	diabetic neuropathy (is_implicated_in)	HGF FTO	2.07e-03	14	144	2	DOID:9743 (is_implicated_in)
Disease	systemic scleroderma (is_marker_for)	HGF FLT4 IL27	2.23e-03	53	144	3	DOID:418 (is_marker_for)
Disease	lean body mass	SNPH ECE1 NCOR2 SLC22A2 DGKI CD79B FTO	2.67e-03	379	144	7	EFO_0004995
Disease	glucose measurement	C2CD4B SGIP1 ZAN IFNLR1 ATXN2 HERC1 FTO	2.71e-03	380	144	7	EFO_0004468
Disease	Tetralogy of Fallot	FLT4 GATA6	2.71e-03	16	144	2	C0039685
Disease	Amyotrophic lateral sclerosis	SETX OPTN	3.07e-03	17	144	2	cv:C0002736
Disease	non-Hodgkin lymphoma (is_implicated_in)	PRF1 CD79B	3.07e-03	17	144	2	DOID:0060060 (is_implicated_in)
Disease	kidney volume	HOXD10 FTO	3.44e-03	18	144	2	EFO_0600044
Disease	essential hypertension (is_implicated_in)	ECE1 FTO	3.44e-03	18	144	2	DOID:10825 (is_implicated_in)
Disease	urolithiasis	DGKD SLC22A2 FTO	3.65e-03	63	144	3	MONDO_0024647
Disease	calcium measurement	TNPO1 HGF DGKD ECE1 ITPKB MELTF CILP2 HPN SLC22A2	3.80e-03	628	144	9	EFO_0004838
Disease	cholangiocarcinoma (is_marker_for)	HGF CST1 MUC6	3.82e-03	64	144	3	DOID:4947 (is_marker_for)
Disease	response to methotrexate, neurotoxicity	DAB2IP PNPLA6	3.83e-03	19	144	2	EFO_0011057, GO_0031427
Disease	electrocardiography	SGIP1 CILP DDR2 GATA6 KCTD1 ZNF592 KBTBD11 CACNA1G	4.61e-03	530	144	8	EFO_0004327
Disease	Diabetes Mellitus, Non-Insulin-Dependent	C2CD4B DGKD ECE1 CAPN10 FTO	4.67e-03	221	144	5	C0011860
Disease	Autoimmune Hepatitis	CARD10 ATXN2	4.67e-03	21	144	2	EFO_0005676
Disease	hepatitis B (is_marker_for)	IL2RB IL27	4.67e-03	21	144	2	DOID:2043 (is_marker_for)

Protein segments in the cluster

Peptide	Gene	Start	Entry
RRDWSAHSIVCRPVQ	TDRD1	196	Q9BXT4
ADFESQCPRRWDSRK	nan	106	A8MZ25
AVRWDAPAITRSSCR	CHRNA10	141	Q9GZZ6
RDLGQLWPADSSCRR	CEP295NL	306	Q96MC4
RPACEQWQRDLASCR	C22orf39	76	Q6P5X5
CRDFWRVRNPTVQLL	EXOC3L1	571	Q86VI1
RWRPLLSSQRNCTIA	EOLA1	26	Q8TE69
RWRPLLSSQRNCTIA	EOLA2	26	Q96DE9
RRQEWFCTRVDPLTL	CARD10	741	Q9BWT7
RVTETLWFNLDRPCV	ANAPC15	11	P60006
RRPTCTESRWKSEEE	CEP68	461	Q76N32
WTPSQSEALRACFER	DUX4L4	26	P0CJ87
NVSARFWLSDCPRTA	ANK1	1206	P16157
RCWSRESEQRPPFSQ	DDR1	886	Q08345
ARSSLRWEEVCREQQ	CD5	306	P06127
STPLAQFREDITWRR	CAPN10	31	Q9HC96
QFREDITWRRPQEIC	CAPN10	36	Q9HC96
ARVCRRWQEAASQPA	FBXL6	141	Q8N531
WTPSQSEALRACFER	DUX4L6	26	P0CJ89
SSRRCWDNGRVNLRP	AHDC1	106	Q5TGY3
SACSRIWQSPRFIAR	CD79B	41	P40259
TSPWVRDLCGQRTTD	ASTN2	506	O75129
VFEDCRNQWSVSRPL	RANBP17	991	Q9H2T7
ASQWSLCPADDERRR	INSYN2A	276	Q6ZSG2
RIPVLECAASWLQRT	INTS15	126	Q96N11
SRFGPIRSCEVIRDW	PPIL4	261	Q8WUA2
ATRESWLQERERECQ	ARHGEF28	1466	Q8N1W1
ERCSFSPWTEHRRCR	CYP27B1	106	O15528
VFASWRQECSSRGRP	DAB2IP	496	Q5VWQ8
PCSLNAFRRSWAERK	MUC6	1046	Q6W4X9
CNRRTPLTNRVWEDR	NCOR2	2436	Q9Y618
TDASLTPWTVRCLRQ	PNPLA6	856	Q8IY17
NVDARRRWSTRCPSF	P2RY11	271	Q96G91
RRWSTRCPSFADIAQ	P2RY11	276	Q96G91
SNSLRTIPVRLFWDC	LRRTM2	166	O43300
ELSPALRNRFTEIWC	MDN1	1531	Q9NU22
LRNRFTEIWCPQSTS	MDN1	1536	Q9NU22
LVRDSRTSPANCTWL	LRP10	46	Q7Z4F1
AWMRNSPSVRERECS	LIN37	121	Q96GY3
ARREVELHWRASQCP	MAPKAPK2	101	P49137
WTPSQSEALRACFER	DUX4	26	Q9UBX2
SSPTRRRWREVEECA	IFNLR1	61	Q8IU57
CRQELSPRNRERWCL	IKBKB	46	O14920
NRVCTRSRWPAVFTR	MST1L	686	Q2TV78
CWRRDTKNRPSFQEI	DDR2	831	Q16832
EWRPDRCQDASEVQR	MAPK4	366	P31152
EWHARCQSRIARTLP	FTO	451	Q9C0B1
PAVATESRRFAAARW	ATXN2	11	Q99700
RSQWREPTRTSDGLC	HERC1	316	Q15751
RRCAAESDLWPRAAD	C2CD4B	56	A6NLJ0
WTPSQSEALRACFER	DUX4L3	26	P0CJ86
TNCTVERITWVSRPD	CD200R1L	91	Q6Q8B3
RPAREAWKRSNFSCA	FAM199X	256	Q6PEV8
RWKQDRETGRFSRPC	KCTD1	126	Q719H9
QYLTDRARWRDCSRP	PRF1	366	P14222
RLSWPVSSCRRFDLE	PDE4C	71	Q08493
AVSTRIRWCRPDCRV	KRTAP1-1	111	Q07627
AVSTRIRWCRPDCRV	KRTAP1-3	101	Q8IUG1
DNISCDDNRERRPTW	LSM14A	371	Q8ND56
DKPCADSERAQRWRL	NALF2	31	O75949
ESWVLTARQCFPSRD	HGF	526	P14210
RGLPWSCSADEVQRF	HNRNPH1	16	P31943
IEGRVECWDPRTRNR	NOL10	196	Q9BSC4
NFELPWLDERSRCRL	MSL1	586	Q68DK7
QTAVCTRDIGWRPDS	ITGB4	241	P16144
TLTPWTQRCVRQADC	PNPLA7	806	Q6ZV29
AAHCFPERNRVLSRW	HPN	201	P05981
CASSRWRRHQEGIPQ	INSL5	41	Q9Y5Q6
ESWNERDPIRALTCF	HERC5	981	Q9UII4
RCTIDDRVTRVAWLN	OPCML	56	Q14982
SSDVNCRRLERLWQE	ABCC5	141	O15440
NCGATATPLWRRDRT	GATA1	206	P15976
LCVPAWEDARRRALD	GALR3	171	O60755
TTTLWRRNAEGEPVC	GATA6	451	Q92908
RGDRWEDLSRSQVRC	EIF2B3	286	Q9NR50
ERGNPSRSLENVCRW	ADAMTS3	321	O15072
VAPRWATRVFAADCL	HEATR5B	1241	Q9P2D3
WRVESNEFCNRPQRK	BMPER	526	Q8N8U9
RCSDPNLGLSWRQEA	C5orf60	311	A6NFR6
RARLPACCLERDSWS	CACNA1G	1241	O43497
KGSCRRPWDRSLENV	DENND2A	236	Q9ULE3
AQRLSPRWCFLDDRS	DGKI	821	O75912
WTPSQSEALRACFER	DUX4L9	26	Q6RFH8
LVRPNTRNRAFSWTC	GDF5-AS1	71	Q5U4N7
AWRRLSDPERLCFIS	IL27	96	Q8NEV9
DRRRWNQTCELLPVS	IL2RB	66	P14784
LRVAWDSRACSPALR	GPAT2	226	Q6NUI2
PQVDSWTDPNRSCRI	HOXD10	76	P28358
PIVSNRWNSDECLRA	BMPR1A	481	P36894
RWTCQTSRRVSSDPA	FAM131A	21	Q6UXB0
ATDRWRRETTRFFCP	AKNA	276	Q7Z591
VPEENWHTRARNFCR	DENND5A	1186	Q6IQ26
WTPSQSEALRACFER	DUX4L7	26	P0CJ90
INFTDAIWSPTCERR	CEP192	436	Q8TEP8
RQLRRLADTPWLCQS	DGKD	1081	Q16760
RWDQIAELPSRRCRA	KLHL3	326	Q9UH77
RSCLSLRDITSSWPQ	HGSNAT	406	Q68CP4
RPWRRATAESASECL	LAMC1	326	P11047
SDTSQPWCIPRQRDR	IGFN1	1126	Q86VF2
LSSREEVQENCVRWR	FAM102A	46	Q5T9C2
SPRSGQRCWAARTQV	ECE1	51	P42892
PWENRRSLVKSRCQE	CST1	126	P01037
WTPSQSEALRACFER	DUX4L5	26	P0CJ88
RTARVRRECWFLPTA	SLC19A2	21	O60779
PRQCRRYEVDWNQST	SLC22A2	86	O15244
CELSQERRTWTFRPQ	NPM2	21	Q86SE8
VSAGSECLSRPWRAR	MICAL2	796	O94851
PRKWLQLETSERRCQ	JARID2	1126	Q92833
RRRCMNRWAEEPSTA	ONECUT3	466	O60422
DRDWRQQRNIPIHSC	OPTN	541	Q96CV9
VARDPRCWAVRRTQL	MIEF2	216	Q96C03
WLDRERTCPLCRSVA	RNFT2	411	Q96EX2
ARNETIARRLWDVSC	RDH11	296	Q8TC12
PVRERSERVALCNWA	ROPN1B	51	Q9BZX4
LQRQPRCWEASVEDL	SLC52A3	241	Q9NQ40
SVRLCSPRQAEAERW	PLEKHH3	176	Q7Z736
ETRPAKWNRTVRTCC	SSPOP	81	A2VEC9
RRRSVQWCAVSQPEA	LTF	21	P02788
LCRDGSRADVTEWRQ	MELTF	256	P08582
ENIRLERETDPCGWR	STRIP2	211	Q9ULQ0
PCGWRTARETFRTEL	STRIP2	221	Q9ULQ0
DPCSSRWDERSLSQR	NKTR	391	P30414
RSEERRTKSWGEQCP	ITPKB	196	P27987
CTRVRAGNREHESWP	NAGPA	51	Q9UK23
SVNPRITRWFSRCIL	PIWIL4	641	Q7Z3Z4
RQTEAIRCSSDWPFQ	SETX	2281	Q7Z333
AVPTVAWLCRSQRRQ	SNPH	436	O15079
RRDEWQECPCSSSRE	KBTBD11	476	O94819
DARDPLDCRRSLLSW	ROBO4	551	Q8WZ75
CARPLRLEARTTDWT	CILP	86	O75339
WRSLRECQGAPVTAS	CILP2	881	Q8IUL8
WERVARLCDFNPKSS	CLTA	211	P09496
LCRQLWPTATERVQT	ATP11A	1096	P98196
LTWNECRAQVDRFPA	RNASEH1	41	O60930
SCRWLFETRPIDQFD	XIRP2	841	A4UGR9
RRPRNWSQCVELARL	UBA6	691	A0AVT1
DREVWPLRFFNRTCH	TYRP1	86	P17643
VWDAFCANRRADRVP	TRAPPC11	36	Q7Z392
PAWAARILRNVSECF	PROM2	716	Q8N271
AVNWRCEPSSTDLRI	SGIP1	691	Q9BQI5
ECEPRSLQARVEWTF	SEMA3B	591	Q13214
SQAECREGELARWTR	PLEKHG4B	506	Q96PX9
QSAVDWTQEPRRRSC	WDR97	1136	A6NE52
WTQEPRRRSCKVART	WDR97	1141	A6NE52
WLSNQVPRRAGERRC	ARHGAP23	291	Q9P227
VSPRFERCGWASQRS	ARHGAP23	371	Q9P227
ERCGWASQRSSARTP	ARHGAP23	376	Q9P227
WCRTRDQNRAPSLTL	TLCD3A	96	Q8TBR7
IRPWCTSLRNIRDNE	TNPO2	801	O14787
RVEARPRLRNTGWTC	ZNF592	971	Q92610
CRDWRAVTTQDAVNP	FLT4	486	P35916
DADGTLCWSRFPQIR	PRAMEF5	421	Q5TYX0
RNWICEGTLERPQRS	ZNF331	81	Q9NQX6
IDCTLPTRRDRKSWE	MYCBPAP	251	Q8TBZ2
TRTVWARCPNGDLAR	TECPR2	1321	O15040
ERCVRESINLFCWTP	TBCK	691	Q8TEA7
PRFQAGTWSRQCRIE	PRAG1	626	Q86YV5
FIRPWCTSLRNIRDN	TNPO1	801	Q92973
QPHARCSLWRRLEAQ	RELT	66	Q969Z4
SQQIRVRNRPSWACR	nan	16	Q6ZR54
RENISEWRNCTIVSP	PRPS1	156	P60891
QWSTDPAQIRRELCS	TESPA1	401	A2RU30
LEAAAQTWRRVCTNP	GTF3C5	231	Q9Y5Q8
WQRTQCSPRETCVEV	VEGFD	106	O43915
CASCRTQRTPLWRDA	ZGLP1	206	P0C6A0
AFAQERWRCLVSTPR	ZNF79	46	Q15937
KSSDGTPDRRWCFRV	TRPV4	766	Q9HBA0
RAPVWAQCASRIDLT	ZAN	2146	Q9Y493
RIVFWSFPRSEREIC	ZSWIM4	66	Q9H7M6
WTPSQSEALRACFER	DUX4L2	26	P0CJ85
RISPDAWEFCQRLSE	LRIG2	301	O94898