Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	phorbol ester receptor activity	UNC13B UNC13C	2.69e-05	2	104	2	GO:0001565
GeneOntologyMolecularFunction	non-kinase phorbol ester receptor activity	UNC13B UNC13C	2.69e-05	2	104	2	GO:0001566
GeneOntologyMolecularFunction	acetyl-CoA carboxylase activity	ACACA ACACB	2.69e-05	2	104	2	GO:0003989
GeneOntologyMolecularFunction	CoA carboxylase activity	ACACA ACACB	3.98e-04	6	104	2	GO:0016421
GeneOntologyMolecularFunction	biotin binding	ACACA ACACB	3.98e-04	6	104	2	GO:0009374
GeneOntologyMolecularFunction	ligase activity, forming carbon-carbon bonds	ACACA ACACB	5.55e-04	7	104	2	GO:0016885
GeneOntologyMolecularFunction	GTPase binding	UNC13B RANBP2 MYRIP BCL2L1 RILP ERRFI1 ACAP2 RIC1	5.91e-04	360	104	8	GO:0051020
GeneOntologyMolecularFunction	lipase activity	PLBD1 PNLIP LIPF PLBD2 LIPA	7.79e-04	138	104	5	GO:0016298
GeneOntologyMolecularFunction	hydrolase activity, acting on glycosyl bonds	GANC GLB1L2 IL18R1 OTOGL BST1	9.44e-04	144	104	5	GO:0016798
GeneOntologyBiologicalProcess	monosaccharide metabolic process	ADCY10 RANBP2 ZMPSTE24 ACACB GANC HECTD4 LIPA IGF2 OTOGL ERRFI1	3.50e-06	310	103	10	GO:0005996
GeneOntologyBiologicalProcess	glucose metabolic process	ADCY10 RANBP2 ZMPSTE24 ACACB GANC HECTD4 LIPA IGF2 ERRFI1	3.74e-06	244	103	9	GO:0006006
GeneOntologyBiologicalProcess	hexose metabolic process	ADCY10 RANBP2 ZMPSTE24 ACACB GANC HECTD4 LIPA IGF2 ERRFI1	1.27e-05	284	103	9	GO:0019318
GeneOntologyBiologicalProcess	malonyl-CoA biosynthetic process	ACACA ACACB	2.47e-05	2	103	2	GO:2001295
GeneOntologyBiologicalProcess	regulation of system process	UNC13B ADCY10 TRPM4 NRG1 FLT1 RELN NPY2R ABL1 ZMPSTE24 ACACB NDUFS4 ERRFI1 MMP2	7.41e-05	734	103	13	GO:0044057
GeneOntologyBiologicalProcess	carbohydrate metabolic process	ADCY10 RANBP2 ZMPSTE24 ACACB GANC HECTD4 GLB1L2 LIPA IGF2 OTOGL ERRFI1 CHST12	9.13e-05	646	103	12	GO:0005975
GeneOntologyBiologicalProcess	regulation of membrane potential	UNC13B ADCY10 TRPM4 RELN NPY2R ABL1 ZMPSTE24 BCL2L1 NDUFS4 LIPA P2RX6	1.10e-04	559	103	11	GO:0042391
GeneOntologyBiologicalProcess	regulation of mitochondrial membrane potential	ADCY10 ABL1 BCL2L1 NDUFS4 LIPA	1.46e-04	100	103	5	GO:0051881
GeneOntologyBiologicalProcess	positive regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway	ADCY10 MMP2	1.47e-04	4	103	2	GO:1903378
GeneOntologyBiologicalProcess	dense core granule priming	UNC13B UNC13C	1.47e-04	4	103	2	GO:0061789
GeneOntologyBiologicalProcess	purine ribonucleotide biosynthetic process	ADCY10 ACACA ACACB BCL2L1 NDUFS4 LIPA SLC27A2	1.65e-04	232	103	7	GO:0009152
GeneOntologyCellularComponent	microtubule	SHROOM2 CFAP126 HOOK1 SYNJ1 SVIL NAV1 EIF3A EML1 TUBD1 TUBB8B	3.26e-04	533	104	10	GO:0005874
GeneOntologyCellularComponent	extracellular matrix	DPT RELN OLFML2B MMP21 MMRN1 IGF2 OTOGL NGLY1 MMP2 PRG4 CTSV	4.24e-04	656	104	11	GO:0031012
GeneOntologyCellularComponent	external encapsulating structure	DPT RELN OLFML2B MMP21 MMRN1 IGF2 OTOGL NGLY1 MMP2 PRG4 CTSV	4.35e-04	658	104	11	GO:0030312
Domain	ACC_central	ACACA ACACB	2.84e-05	2	100	2	PF08326
Domain	AcCoA_COase_cen	ACACA ACACB	2.84e-05	2	100	2	IPR013537
Domain	Phospholip_B	PLBD1 PLBD2	2.84e-05	2	100	2	PF04916
Domain	PLipase_B-like	PLBD1 PLBD2	2.84e-05	2	100	2	IPR007000
Domain	-	DGKB DGKG	8.48e-05	3	100	2	1.10.238.110
Domain	DAG_kinase_N	DGKB DGKG	8.48e-05	3	100	2	PF14513
Domain	Unc-13	UNC13B UNC13C	8.48e-05	3	100	2	IPR027080
Domain	DAG_kinase_typeI_N	DGKB DGKG	8.48e-05	3	100	2	IPR029477
Domain	-	MMP21 MMP2	1.69e-04	4	100	2	1.10.101.10
Domain	Carboxyl_trans	ACACA ACACB	1.69e-04	4	100	2	PF01039
Domain	COA_CT_CTER	ACACA ACACB	1.69e-04	4	100	2	PS50989
Domain	COA_CT_NTER	ACACA ACACB	1.69e-04	4	100	2	PS50980
Domain	COA_CT_N	ACACA ACACB	1.69e-04	4	100	2	IPR011762
Domain	COA_CT_C	ACACA ACACB	1.69e-04	4	100	2	IPR011763
Domain	Carboxyl_trans	ACACA ACACB	1.69e-04	4	100	2	IPR000022
Domain	Hemopexin-like_dom	MMP21 MMP2 PRG4	2.44e-04	23	100	3	IPR000585
Domain	Hemopexin-like_repeat	MMP21 MMP2 PRG4	2.44e-04	23	100	3	IPR018487
Domain	HEMOPEXIN	MMP21 MMP2 PRG4	2.44e-04	23	100	3	PS00024
Domain	-	MMP21 MMP2 PRG4	2.44e-04	23	100	3	2.110.10.10
Domain	HEMOPEXIN_2	MMP21 MMP2 PRG4	2.44e-04	23	100	3	PS51642
Domain	HX	MMP21 MMP2 PRG4	2.44e-04	23	100	3	SM00120
Domain	Hemopexin	MMP21 MMP2 PRG4	2.44e-04	23	100	3	PF00045
Domain	C1_1	UNC13B DGKB DGKG UNC13C	2.46e-04	57	100	4	PF00130
Domain	Munc13_dom-2	UNC13B UNC13C	2.81e-04	5	100	2	IPR014772
Domain	Biotin_BS	ACACA ACACB	2.81e-04	5	100	2	IPR001882
Domain	MHD2	UNC13B UNC13C	2.81e-04	5	100	2	PS51259
Domain	Munc13_subgr_dom-2	UNC13B UNC13C	2.81e-04	5	100	2	IPR019558
Domain	Biotin_COase_C	ACACA ACACB	2.81e-04	5	100	2	IPR005482
Domain	BC	ACACA ACACB	2.81e-04	5	100	2	PS50979
Domain	Membr_traf_MHD	UNC13B UNC13C	2.81e-04	5	100	2	PF10540
Domain	Biotin_carb_C	ACACA ACACB	2.81e-04	5	100	2	SM00878
Domain	Biotin_carb_C	ACACA ACACB	2.81e-04	5	100	2	PF02785
Domain	Biotin_carboxylation_dom	ACACA ACACB	2.81e-04	5	100	2	IPR011764
Domain	CPSASE_1	ACACA ACACB	2.81e-04	5	100	2	PS00866
Domain	DUF1041	UNC13B UNC13C	2.81e-04	5	100	2	SM01145
Domain	BIOTIN	ACACA ACACB	2.81e-04	5	100	2	PS00188
Domain	LIPASE_SER	PNLIP LIPF LIPA	3.54e-04	26	100	3	PS00120
Domain	ZF_DAG_PE_1	UNC13B DGKB DGKG UNC13C	3.84e-04	64	100	4	PS00479
Domain	ZF_DAG_PE_2	UNC13B DGKB DGKG UNC13C	3.84e-04	64	100	4	PS50081
Domain	C1	UNC13B DGKB DGKG UNC13C	4.08e-04	65	100	4	SM00109
Domain	Lipase_euk	LIPF LIPA	4.20e-04	6	100	2	IPR025483
Domain	Rudment_hybrid_motif	ACACA ACACB	4.20e-04	6	100	2	IPR011054
Domain	Abhydro_lipase	LIPF LIPA	4.20e-04	6	100	2	PF04083
Domain	CPSASE_2	ACACA ACACB	4.20e-04	6	100	2	PS00867
Domain	AB_hydrolase_lipase	LIPF LIPA	4.20e-04	6	100	2	IPR006693
Domain	PE/DAG-bd	UNC13B DGKB DGKG UNC13C	4.32e-04	66	100	4	IPR002219
Domain	Munc13_1	UNC13B UNC13C	5.86e-04	7	100	2	IPR014770
Domain	MHD1	UNC13B UNC13C	5.86e-04	7	100	2	PS51258
Domain	CbamoylP_synth_lsu-like_ATP-bd	ACACA ACACB	5.86e-04	7	100	2	IPR005479
Domain	BC-like_N	ACACA ACACB	5.86e-04	7	100	2	IPR005481
Domain	DUF1041	UNC13B UNC13C	5.86e-04	7	100	2	PF06292
Domain	CPSase_L_D2	ACACA ACACB	5.86e-04	7	100	2	PF02786
Domain	CAPS_dom	UNC13B UNC13C	5.86e-04	7	100	2	IPR010439
Domain	Biotin_carb_N	ACACA ACACB	5.86e-04	7	100	2	PF00289
Domain	Biotin_lipoyl	ACACA ACACB	9.97e-04	9	100	2	PF00364
Domain	DAGK_acc	DGKB DGKG	1.24e-03	10	100	2	PF00609
Domain	Diacylglycerol_kin_accessory	DGKB DGKG	1.24e-03	10	100	2	IPR000756
Domain	BIOTINYL_LIPOYL	ACACA ACACB	1.24e-03	10	100	2	PS50968
Domain	Biotin_lipoyl	ACACA ACACB	1.24e-03	10	100	2	IPR000089
Domain	DAGKa	DGKB DGKG	1.24e-03	10	100	2	SM00045
Domain	Single_hybrid_motif	ACACA ACACB	1.81e-03	12	100	2	IPR011053
Domain	-	ACACA ACACB	2.13e-03	13	100	2	3.40.50.20
Domain	ATP_GRASP	ACACA ACACB	2.48e-03	14	100	2	PS50975
Domain	ATP-grasp	ACACA ACACB	2.48e-03	14	100	2	IPR011761
Domain	PreATP-grasp_dom	ACACA ACACB	2.48e-03	14	100	2	IPR016185
Domain	DAGKc	DGKB DGKG	2.48e-03	14	100	2	SM00046
Domain	Diacylglycerol_kinase_cat_dom	DGKB DGKG	2.85e-03	15	100	2	IPR001206
Domain	DAGK	DGKB DGKG	2.85e-03	15	100	2	PS50146
Domain	DAGK_cat	DGKB DGKG	2.85e-03	15	100	2	PF00781
Domain	-	ACACA ACACB	2.85e-03	15	100	2	3.30.1490.20
Domain	Hemopexin_CS	MMP2 PRG4	3.66e-03	17	100	2	IPR018486
Domain	NAD/diacylglycerol_kinase	DGKB DGKG	3.66e-03	17	100	2	IPR016064
Domain	BACK	KLHL10 BTBD1 KLHL30	4.09e-03	60	100	3	SM00875
Domain	ATP_grasp_subdomain_1	ACACA ACACB	4.11e-03	18	100	2	IPR013815
Domain	-	ACACA ACACB	4.11e-03	18	100	2	3.30.470.20
Domain	BACK	KLHL10 BTBD1 KLHL30	4.28e-03	61	100	3	IPR011705
Domain	BACK	KLHL10 BTBD1 KLHL30	4.28e-03	61	100	3	PF07707
Domain	PG_binding_1	MMP21 MMP2	5.06e-03	20	100	2	PF01471
Domain	Peptidoglycan-bd-like	MMP21 MMP2	5.06e-03	20	100	2	IPR002477
Pubmed	Sequence comparison of human and mouse genes reveals a homologous block structure in the promoter regions.	UNC13B SERPINB7 DPT KLHL10 CCDC174 SPTAN1 LIPF GSDMB CDK14 HEPH IGF2 SYNJ1 DMKN MMP2 ANKRD7	9.00e-06	1293	106	15	15342556
Pubmed	Genetic inhibition of hepatic acetyl-CoA carboxylase activity increases liver fat and alters global protein acetylation.	ACACA ACACB	9.20e-06	2	106	2	24944901
Pubmed	Hormonal regulation of acetyl-CoA carboxylase isoenzyme gene transcription.	ACACA ACACB	9.20e-06	2	106	2	20139635
Pubmed	Inhibition of Acetyl-CoA Carboxylase 1 (ACC1) and 2 (ACC2) Reduces Proliferation and De Novo Lipogenesis of EGFRvIII Human Glioblastoma Cells.	ACACA ACACB	9.20e-06	2	106	2	28081256
Pubmed	Acetyl-CoA carboxylase inhibition by ND-630 reduces hepatic steatosis, improves insulin sensitivity, and modulates dyslipidemia in rats.	ACACA ACACB	9.20e-06	2	106	2	26976583
Pubmed	Munc13-independent vesicle priming at mouse photoreceptor ribbon synapses.	UNC13B UNC13C	9.20e-06	2	106	2	22674279
Pubmed	AMPK-dependent inhibitory phosphorylation of ACC is not essential for maintaining myocardial fatty acid oxidation.	ACACA ACACB	9.20e-06	2	106	2	25001074
Pubmed	The subcellular localization of acetyl-CoA carboxylase 2.	ACACA ACACB	9.20e-06	2	106	2	10677481
Pubmed	Susceptibility of podocytes to palmitic acid is regulated by fatty acid oxidation and inversely depends on acetyl-CoA carboxylases 1 and 2.	ACACA ACACB	9.20e-06	2	106	2	24338821
Pubmed	IGF-2 and FLT-1/VEGF-R1 mRNA levels reveal distinctions and similarities between congenital and common infantile hemangioma.	FLT1 IGF2	9.20e-06	2	106	2	18287964
Pubmed	De novo fatty acid synthesis controls the fate between regulatory T and T helper 17 cells.	ACACA ACACB	9.20e-06	2	106	2	25282359
Pubmed	Acetyl-CoA carboxylase rewires cancer metabolism to allow cancer cells to survive inhibition of the Warburg effect by cetuximab.	ACACA ACACB	9.20e-06	2	106	2	27693630
Pubmed	Glucocorticoids uncover a critical role for ASH2L on BCL-X expression regulation in leukemia cells.	BCL2L1 ASH2L	9.20e-06	2	106	2	31870784
Pubmed	The role of megsin, a serine protease inhibitor, in diabetic mesangial matrix accumulation.	SERPINB7 MMP2	9.20e-06	2	106	2	18580857
Pubmed	Effects of PKB/Akt inhibitors on insulin-stimulated lipogenesis and phosphorylation state of lipogenic enzymes in white adipose tissue.	ACACA ACACB	9.20e-06	2	106	2	32215608
Pubmed	Activity and structure of human acetyl-CoA carboxylase targeted by a specific inhibitor.	ACACA ACACB	9.20e-06	2	106	2	29772612
Pubmed	Phosphorylation of Acetyl-CoA Carboxylase by AMPK Reduces Renal Fibrosis and Is Essential for the Anti-Fibrotic Effect of Metformin.	ACACA ACACB	9.20e-06	2	106	2	29976587
Pubmed	Structure and regulation of acetyl-CoA carboxylase genes of metazoa.	ACACA ACACB	9.20e-06	2	106	2	15749055
Pubmed	AMPK signaling to acetyl-CoA carboxylase is required for fasting- and cold-induced appetite but not thermogenesis.	ACACA ACACB	9.20e-06	2	106	2	29433631
Pubmed	Blocking AMPK signalling to acetyl-CoA carboxylase increases cisplatin-induced acute kidney injury and suppresses the benefit of metformin.	ACACA ACACB	9.20e-06	2	106	2	36076520
Pubmed	Identification of phospholipase B from Dictyostelium discoideum reveals a new lipase family present in mammals, flies and nematodes, but not yeast.	PLBD1 PLBD2	9.20e-06	2	106	2	15193148
Pubmed	Inhibition of hepatic lipogenesis enhances liver tumorigenesis by increasing antioxidant defence and promoting cell survival.	ACACA ACACB	9.20e-06	2	106	2	28290443
Pubmed	Inhibition of Acetyl-CoA Carboxylase by Phosphorylation or the Inhibitor ND-654 Suppresses Lipogenesis and Hepatocellular Carcinoma.	ACACA ACACB	9.20e-06	2	106	2	30244972
Pubmed	Neuronal-specific deficiency of the splicing factor Tra2b causes apoptosis in neurogenic areas of the developing mouse brain.	NRG1 SLU7 TUBD1	1.50e-05	16	106	3	24586484
Pubmed	Quantitative proteomic profiling of the extracellular matrix of pancreatic islets during the angiogenic switch and insulinoma progression.	DPT RELN MMRN1 IGF2 NGLY1 CTSV	1.68e-05	175	106	6	28071719
Pubmed	AMPK activation by SC4 inhibits noradrenaline-induced lipolysis and insulin-stimulated lipogenesis in white adipose tissue.	ACACA ACACB	2.76e-05	3	106	2	34668531
Pubmed	AMPK-ACC signaling modulates platelet phospholipids and potentiates thrombus formation.	ACACA ACACB	2.76e-05	3	106	2	30018077
Pubmed	Double deficiency of cathepsins B and L results in massive secretome alterations and suggests a degradative cathepsin-MMP axis.	MMP2 CTSV	2.76e-05	3	106	2	23811845
Pubmed	c-Abl tyrosine kinase regulates the human Rad9 checkpoint protein in response to DNA damage.	ABL1 BCL2L1	2.76e-05	3	106	2	11971963
Pubmed	Acetyl-coenzyme A carboxylase alpha gene variations may be associated with the direct effects of some antipsychotics on triglyceride levels.	ACACA ACACB	2.76e-05	3	106	2	19846279
Pubmed	Exploring genetic variations that may be associated with the direct effects of some antipsychotics on lipid levels.	ACACA ACACB	2.76e-05	3	106	2	18031993
Pubmed	Induced polymerization of mammalian acetyl-CoA carboxylase by MIG12 provides a tertiary level of regulation of fatty acid synthesis.	ACACA ACACB	2.76e-05	3	106	2	20457939
Pubmed	Macrophage acetyl-CoA carboxylase regulates acute inflammation through control of glucose and lipid metabolism.	ACACA ACACB	2.76e-05	3	106	2	36417534
Pubmed	The expression of STAT3, BCL-XL and MMP-2 proteins in colon adenocarcinomas and their relationship with prognostic factors.	BCL2L1 MMP2	2.76e-05	3	106	2	25110240
Pubmed	Precursor IGF-II (proIGF-II) and mature IGF-II (mIGF-II) induce Bcl-2 And Bcl-X L expression through different signaling pathways in breast cancer cells.	BCL2L1 IGF2	2.76e-05	3	106	2	18428028
Pubmed	Heterogeneous Presynaptic Distribution of Munc13 Isoforms at Retinal Synapses and Identification of an Unconventional Bipolar Cell Type with Dual Expression of Munc13 Isoforms: A Study Using Munc13-EXFP Knock-in Mice.	UNC13B UNC13C	2.76e-05	3	106	2	33105896
Pubmed	Differential activation of recombinant human acetyl-CoA carboxylases 1 and 2 by citrate.	ACACA ACACB	2.76e-05	3	106	2	18455495
Pubmed	The Munc13 proteins differentially regulate readily releasable pool dynamics and calcium-dependent recovery at a central synapse.	UNC13B UNC13C	2.76e-05	3	106	2	23658173
Pubmed	Mig6 is a sensor of EGF receptor inactivation that directly activates c-Abl to induce apoptosis during epithelial homeostasis.	ABL1 ERRFI1	2.76e-05	3	106	2	22975324
Pubmed	Protein kinase PKC delta and c-Abl are required for mitochondrial apoptosis induction by genotoxic stress in the absence of p53, p73 and Fas receptor.	ABL1 BCL2L1	2.76e-05	3	106	2	16631755
Pubmed	Acetyl CoA Carboxylase Inhibition Reduces Hepatic Steatosis but Elevates Plasma Triglycerides in Mice and Humans: A Bedside to Bench Investigation.	ACACA ACACB	2.76e-05	3	106	2	28877461
Pubmed	Specific pattern of LKB1 and phospho-acetyl-CoA carboxylase protein immunostaining in human normal tissues and lung carcinomas.	ACACA ACACB	2.76e-05	3	106	2	17521700
Pubmed	Acetyl-CoA carboxylase 1 and 2 inhibition ameliorates steatosis and hepatic fibrosis in a MC4R knockout murine model of nonalcoholic steatohepatitis.	ACACA ACACB	2.76e-05	3	106	2	31990961
Pubmed	Nonconserved Ca(2+)/calmodulin binding sites in Munc13s differentially control synaptic short-term plasticity.	UNC13B UNC13C	2.76e-05	3	106	2	22966208
Pubmed	The Na+/Glucose Cotransporter Inhibitor Canagliflozin Activates AMPK by Inhibiting Mitochondrial Function and Increasing Cellular AMP Levels.	ACACA ACACB	2.76e-05	3	106	2	27381369
Pubmed	Hepatic de novo lipogenesis is present in liver-specific ACC1-deficient mice.	ACACA ACACB	2.76e-05	3	106	2	17210641
Pubmed	Aberrant morphology and residual transmitter release at the Munc13-deficient mouse neuromuscular synapse.	UNC13B UNC13C	2.76e-05	3	106	2	15988013
Pubmed	Acetyl CoA Carboxylase Inhibition Reduces Hepatic Steatosis but Elevates Plasma Triglycerides in Mice and Humans: A Bedside to Bench Investigation.	ACACA ACACB	2.76e-05	3	106	2	28768177
Pubmed	Genetic variability of the fatty acid synthase pathway is not associated with prostate cancer risk in the European Prospective Investigation on Cancer (EPIC).	ACACA ACACB SLC27A2	4.06e-05	22	106	3	20965718
Pubmed	Single phosphorylation sites in Acc1 and Acc2 regulate lipid homeostasis and the insulin-sensitizing effects of metformin.	ACACA ACACB	5.50e-05	4	106	2	24185692
Pubmed	Cloning, analysis, and chromosomal localization of Notch-1, a mouse homolog of Drosophila Notch.	ABL1 SPTAN1	5.50e-05	4	106	2	8449489
Pubmed	Crystal structure of Spot 14, a modulator of fatty acid synthesis.	ACACA ACACB	5.50e-05	4	106	2	20952656
Pubmed	Substance P accelerates the progression of human esophageal squamous cell carcinoma via MMP-2, MMP-9, VEGF-A, and VEGFR1 overexpression.	FLT1 MMP2	5.50e-05	4	106	2	32436041
Pubmed	Identification of a candidate human spectrin Src homology 3 domain-binding protein suggests a general mechanism of association of tyrosine kinases with the spectrin-based membrane skeleton.	ABL1 SPTAN1	5.50e-05	4	106	2	9593709
Pubmed	Hepatic malonyl-CoA synthesis restrains gluconeogenesis by suppressing fat oxidation, pyruvate carboxylation, and amino acid availability.	ACACA ACACB	5.50e-05	4	106	2	38447582
Pubmed	Biosynthesis of alkyl lysophosphatidic acid by diacylglycerol kinases.	DGKB DGKG	9.15e-05	5	106	2	22627129
Pubmed	Animal models of gene-environment interactions in schizophrenia.	NRG1 RELN	9.15e-05	5	106	2	19379776
Pubmed	Metformin-induced increases in GDF15 are important for suppressing appetite and promoting weight loss.	ACACA ACACB	9.15e-05	5	106	2	32694673
Pubmed	Acetyl-CoA carboxylase 1 is a suppressor of the adipocyte thermogenic program.	ACACA ACACB	9.15e-05	5	106	2	37163372
Pubmed	An active vesicle priming machinery suppresses axon regeneration upon adult CNS injury.	UNC13B UNC13C	9.15e-05	5	106	2	34706221
Pubmed	The forkhead transcription factor Foxi1 is a master regulator of vacuolar H-ATPase proton pump subunits in the inner ear, kidney and epididymis.	ATP6V0A4 FOXI1	9.15e-05	5	106	2	19214237
Pubmed	Secretion of MMP-2 and MMP-9 induced by VEGF autocrine loop correlates with clinical features in childhood acute lymphoblastic leukemia.	FLT1 MMP2	9.15e-05	5	106	2	18829111
Pubmed	Maternal transmission of a humanised Igf2r allele results in an Igf2 dependent hypomorphic and non-viable growth phenotype.	IGF2 CTSV	9.15e-05	5	106	2	23468951
Pubmed	Role of Myeloperoxidase Oxidants in the Modulation of Cellular Lysosomal Enzyme Function: A Contributing Factor to Macrophage Dysfunction in Atherosclerosis?	LIPA CTSV	9.15e-05	5	106	2	27997605
Pubmed	Hereditary Distal Renal Tubular Acidosis	ATP6V0A4 FOXI1	9.15e-05	5	106	2	31600044
Pubmed	Identification of a Munc13-sensitive step in chromaffin cell large dense-core vesicle exocytosis.	UNC13B UNC13C	9.15e-05	5	106	2	26575293
Pubmed	TRB3 links the E3 ubiquitin ligase COP1 to lipid metabolism.	ACACA ACACB	9.15e-05	5	106	2	16794074
Pubmed	Nuclear Gene 33/Mig6 regulates the DNA damage response through an ATM serine/threonine kinase-dependent mechanism.	ABL1 ERRFI1	1.37e-04	6	106	2	28842482
Pubmed	Potential genetic variants in schizophrenia: a Bayesian analysis.	NRG1 RELN	1.37e-04	6	106	2	17366345
Pubmed	LKB1 deletion causes early changes in atrial channel expression and electrophysiology prior to atrial fibrillation.	ACACA ACACB MMP2	1.54e-04	34	106	3	26378152
Pubmed	Inceptor counteracts insulin signalling in β-cells to control glycaemia.	ABL1 ACACA ACACB	1.54e-04	34	106	3	33505018
Pubmed	Increased expression of HIF-1alpha, VEGF-A and its receptors, MMP-2, TIMP-1, and ADAMTS-1 at the venous stenosis of arteriovenous fistula in a mouse model with renal insufficiency.	FLT1 MMP2	1.91e-04	7	106	2	20598569
Pubmed	Comparative mapping of mouse chromosome 2 and human chromosome 9q: the genes for gelsolin and dopamine beta-hydroxylase map to mouse chromosome 2.	ABL1 SPTAN1	1.91e-04	7	106	2	1315305
Pubmed	Defective prolactin signaling impairs pancreatic β-cell development during the perinatal period.	PNLIP IGF2	1.91e-04	7	106	2	24064341
Pubmed	Munc13 supports fusogenicity of non-docked vesicles at synapses with disrupted active zones.	UNC13B UNC13C	1.91e-04	7	106	2	36398873
Pubmed	Poly (ADP-Ribose) Polymerase 1 Regulates Cajal-Retzius Cell Development and Neural Precursor Cell Adhesion.	RELN NAV1	1.91e-04	7	106	2	34708032
Pubmed	The AMPK-HOXB9-KRAS axis regulates lung adenocarcinoma growth in response to cellular energy alterations.	ACACA ACACB	2.55e-04	8	106	2	36001969
Pubmed	Neuregulin repellent signaling via ErbB4 restricts GABAergic interneurons to migratory paths from ganglionic eminence to cortical destinations.	NRG1 RELN	2.55e-04	8	106	2	22376909
Pubmed	Expression of mouse Foxi class genes in early craniofacial development.	FOXI2 FOXI1	2.55e-04	8	106	2	15376323
Pubmed	MiRNA199a-3p suppresses tumor growth, migration, invasion and angiogenesis in hepatocellular carcinoma by targeting VEGFA, VEGFR1, VEGFR2, HGF and MMP2.	FLT1 MMP2	2.55e-04	8	106	2	28358369
Pubmed	Unconventional molecular regulation of synaptic vesicle replenishment in cochlear inner hair cells.	UNC13B UNC13C	2.55e-04	8	106	2	25609709
Pubmed	Defining the identity of mouse embryonic dermal fibroblasts.	IGF2 MMP2	2.55e-04	8	106	2	27265328
Pubmed	Shotgun sequencing of the human transcriptome with ORF expressed sequence tags.	FLT1 ACACA DUOX2 GLB1L2 BTBD1 GRAMD1B TRANK1 KDM4B	2.96e-04	552	106	8	10737800
Pubmed	ESCPE-1 mediates retrograde endosomal sorting of the SARS-CoV-2 host factor Neuropilin-1.	ZMPSTE24 SLC43A3 GLB1L2 PLBD2 GRAMD1B SERPINI1 TRAM1 SVIL CHST12 EIF3A NGLY1 MMP2	3.02e-04	1201	106	12	35696571
Pubmed	A central chaperone-like role for 14-3-3 proteins in human cells.	ABL1 ACACA SPTAN1 MAP3K20 CDK14 DENND4C HOOK1 SYNJ1 SVIL NAV1	3.08e-04	861	106	10	36931259
Pubmed	Physiogenomic analysis of statin-treated patients: domain-specific counter effects within the ACACB gene on low-density lipoprotein cholesterol?	FLT1 ACACA ACACB LIPF LIPA	3.14e-04	192	106	5	20602615
Pubmed	The unique N-terminal domain of the cAMP phosphodiesterase PDE4D4 allows for interaction with specific SH3 domains.	ABL1 SPTAN1	3.27e-04	9	106	2	10571082
Pubmed	Spontaneous and induced mouse mutations with cerebellar dysfunctions: behavior and neurochemistry.	RELN UNC13C	3.27e-04	9	106	2	16499884
Pubmed	Involvement of insulin-like growth factor 2 in angiogenic factor transcription in Bi-maternal mouse conceptuses.	FLT1 IGF2	3.27e-04	9	106	2	19881219
Pubmed	Analyses of shared genetic factors between asthma and obesity in children.	GSDMB DGKG IL18R1	4.05e-04	47	106	3	20816195
Pubmed	SIRT1 regulates Tat-induced HIV-1 transactivation through activating AMP-activated protein kinase.	ACACA ACACB	4.08e-04	10	106	2	19720090
Pubmed	Physiogenomic comparison of edema and BMI in patients receiving rosiglitazone or pioglitazone.	ACACA ACACB LIPF LIPA	4.64e-04	117	106	4	18996102
Pubmed	Molecular and functional architecture of striatal dopamine release sites.	UNC13B UNC13C	4.97e-04	11	106	2	34767769
Pubmed	Diacylglycerol kinase delta regulates protein kinase C and epidermal growth factor receptor signaling.	DGKB DGKG	4.97e-04	11	106	2	17021016
Pubmed	A large-scale, consortium-based genomewide association study of asthma.	GSDMB IL18R1	4.97e-04	11	106	2	20860503
Pubmed	The RNA binding protein MEX3A promotes tumor progression of breast cancer by post-transcriptional regulation of IGFBP4.	ABL1 SPTAN1 RILP LIPA SVIL NAV1	5.54e-04	332	106	6	37433992
Pubmed	Comparative mapping of 50 human chromosome 9 loci in the laboratory mouse.	ABL1 SPTAN1 CTSV	5.77e-04	53	106	3	7774911
Pubmed	HDAC1/NFκB pathway is involved in curcumin inhibiting of Tat-mediated long terminal repeat transactivation.	ACACA ACACB	5.95e-04	12	106	2	21344388
Pubmed	AMP-activated protein kinase (AMPK) activity is not required for neuronal development but regulates axogenesis during metabolic stress.	ACACA ACACB	5.95e-04	12	106	2	21436046
Pubmed	Genome-wide CRISPR screen identifies HNRNPL as a prostate cancer dependency regulating RNA splicing.	TRPM4 ACACA HECTD4 MYRIP PPM1K CDK14 SHROOM2 PLBD2 IGF2 NAV1 FOLH1B RIC1 KDM4B	6.06e-04	1489	106	13	28611215
GeneFamily	Lipases\|Arylacetamide deacetylase family	PNLIP LIPF LIPA	7.12e-05	22	67	3	464
GeneFamily	UNC13 homologs	UNC13B UNC13C	8.08e-05	4	67	2	836
GeneFamily	EF-hand domain containing\|Diacylglycerol kinases	DGKB DGKG	5.97e-04	10	67	2	1178
ToppCell	droplet-Kidney-nan-18m-Epithelial-kidney_mesangial_cell\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MAP3K20 MYRIP DGKB IGF2 SERPINI1 KLHL30 EML1	3.42e-07	188	106	7	d1a4cd4db95d8d32b79156290f7867f32824cc87
ToppCell	10x3'2.3-week_12-13-Mesenchymal_fibro-stroma-endosteal_fibroblast\|week_12-13 / cell types per 3 fetal stages;per 3',per 5'	OLFML2B DGKB IGF2 ERRFI1 MMP2 PRG4 CA4	3.54e-07	189	106	7	c392491aabe8a3e90974ab2ea123bbbe5200439d
ToppCell	RV-10._Endothelium_II\|World / Chamber and Cluster_Paper	NRG1 FLT1 MYRIP BCL2L1 SHROOM2 IL18R1 MMRN1	4.08e-07	193	106	7	2531266bc57339d4e2b22a88817008e32b8c1598
ToppCell	background-Endothelial_cells\|background / Sample and Cell Type and Tumor Cluster (all cells)	FLT1 RELN MYRIP DGKG DENND4C MMRN1 EML1	4.53e-07	196	106	7	e6fb0bfab1779ec64a8c35d01519eaafbf62e977
ToppCell	Bronchial-NucSeq-Endothelial-Endothelia_vascular-VE_capillary\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	FLT1 STARD8 SHROOM2 IL18R1 NAV1 EML1 CA4	4.69e-07	197	106	7	81718164c9802ee20c860ffbda7e62d5e9a76f16
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell-Intercalated_Cell_Type_B\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	MYRIP DGKB GRAMD1B ATP6V0A4 UNC13C FOXI1	2.80e-06	165	106	6	dc570154baed59ed109e5369589448e075ba66a9
ToppCell	Anterior_Cingulate_gyrus_(CgG)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_D_(IT_RORB_THEMIS_LINC00507)_4\|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	NRG1 NPY2R LIPA OTOGL FOLH1B UNC13C	3.44e-06	171	106	6	f648789e6aefe508bb748401bf9b3cd830fb0ddf
ToppCell	Anterior_Cingulate_gyrus_(CgG)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_D_(IT_RORB_THEMIS_LINC00507)_4-Exc_L4-5_RORB_LCN15\|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	NRG1 NPY2R LIPA OTOGL FOLH1B UNC13C	3.44e-06	171	106	6	6a489a75eeab2a2d48d604682e93599c20a945fe
ToppCell	facs-Heart-LV-24m-Mesenchymal-smooth_muscle_cell\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MAP3K20 DGKB DGKG IGF2 SERPINI1 UNC13C	3.80e-06	174	106	6	197686570cec6d96a92e77e6409325d3bfe6f991
ToppCell	facs-Heart-LV-24m-Mesenchymal-smooth_muscle_cell\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MAP3K20 DGKB DGKG IGF2 SERPINI1 UNC13C	3.80e-06	174	106	6	2eee7b5471672b439f95eba11494c2adf8cb7006
ToppCell	Mid-temporal_gyrus_(MTG)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_D_(IT_RORB_THEMIS_LINC00507)_4-Exc_L4-5_RORB_LCN15\|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	NRG1 NPY2R LIPA OTOGL FOLH1B UNC13C	3.80e-06	174	106	6	2947e5906b172d149412fa4e77476fce4ea695d2
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell-Intercalated_Cell_Type_B\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	MYRIP DGKB ATP6V0A4 UNC13C SCAI FOXI1	4.06e-06	176	106	6	6c7edf1cb38644500bce6c5a1dd90bbe17415cdb
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell-Intercalated_Cell_Type_B\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	MYRIP DGKB ATP6V0A4 UNC13C SCAI FOXI1	4.62e-06	180	106	6	cfc8bfbfd3617aabbb49f9730c29b673ca157e74
ToppCell	5'-Parenchyma_lung-Mesenchymal-Mesenchymal_Myocytic-tracheobronchial_smooth_muscle_cell-SM_activated_stress_response\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	OLFML2B MAP3K20 DGKB DGKG SERPINI1 OTOGL	5.24e-06	184	106	6	603faafb7b289a3c0242c84fc800c050c8a092ea
ToppCell	5'-Parenchyma_lung-Mesenchymal-Mesenchymal_Myocytic-tracheobronchial_smooth_muscle_cell-SM_activated_stress_response-SM_activated_stress_response_L.2.3.0.1\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	OLFML2B MAP3K20 DGKB DGKG SERPINI1 OTOGL	5.24e-06	184	106	6	c350504bfe0ec31cd2fc2199de9b5fff151a8c5e
ToppCell	droplet-Kidney-nan-18m-Epithelial-Pecam____Kidney_cortex_artery_cell\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FLT1 MYRIP IGF2 SERPINI1 EML1 MMP2	5.75e-06	187	106	6	e93cad16a087d1443cbf4e1690dc1b35d7a84c41
ToppCell	droplet-Kidney-nan-3m-Epithelial-Pecam____Kidney_cortex_artery_cell\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MYRIP DGKB IGF2 SERPINI1 EML1 MMP2	5.93e-06	188	106	6	ec0e241de2c8310b4417b9d4e2420d7a1662f1c0
ToppCell	Control-Endothelial-VE_Capillary_B\|Endothelial / Disease state, Lineage and Cell class	UNC13B FLT1 IL18R1 NAV1 EML1 CA4	6.30e-06	190	106	6	7f3f419fffe02934b6f27b697f7a6401072491ed
ToppCell	ILEUM-non-inflamed-(7)_Endothelial_cell-(7)_Lymphatics\|(7)_Endothelial_cell / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)	PLBD1 RELN MMRN1 IGF2 ERRFI1 MMP2	6.30e-06	190	106	6	9ce301841ce9486701fa28eb2a9929e35d476878
ToppCell	droplet-Fat-Mat-18m-Mesenchymal\|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DPT OLFML2B SLC43A3 ERRFI1 NAV1 MMP2	6.89e-06	193	106	6	ebd090d7801480b3cee45caac3d30cc991836769
ToppCell	droplet-Fat-Mat-18m-Mesenchymal-Cd34+\|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DPT OLFML2B SLC43A3 ERRFI1 NAV1 MMP2	6.89e-06	193	106	6	22c58032e58730715224d7934968ce92d150b0e8
ToppCell	droplet-Heart-nan-24m-Mesenchymal-fibroblast\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DPT OLFML2B SLC43A3 ERRFI1 SNTG1 MMP2	6.89e-06	193	106	6	d08919db9601941569b9a143dad4d8e6f56a4389
ToppCell	droplet-Fat-Mat-18m-Mesenchymal-mesenchymal_stem_cell_of_adipose\|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DPT OLFML2B SLC43A3 ERRFI1 NAV1 MMP2	6.89e-06	193	106	6	573ad2f848bede1fe20c7b4b352a9242ec294725
ToppCell	renal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial-Ascending_Vasa_Recta_Endothelial_Cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	FLT1 RELN MYRIP DGKG NAV1 EML1	7.09e-06	194	106	6	fa6d51f36a3dae8763a595c20892987ed454c0f0
ToppCell	PND03-Endothelial-Endothelial_blood-vessel-Microvascular_EC\|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	FLT1 STARD8 SLC43A3 NAV1 ACAP2 CA4	7.30e-06	195	106	6	d700e959e060932e3854a9cf294799465efbe18b
ToppCell	droplet-Bladder-nan-24m-Endothelial\|Bladder / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FLT1 RELN DGKB DGKG MMRN1 CA4	7.52e-06	196	106	6	9a90dd26e7a43e3fd55e7c5d8354cfa4cdd5a6cc
ToppCell	wk_08-11-Mesenchymal-Fibroblast-Adventitial_fibro\|wk_08-11 / Celltypes from embryonic and fetal-stage human lung	DPT NPY2R OLFML2B IGF2 BST1 SVIL	7.52e-06	196	106	6	eed9fe83ffc1f79493b70778962a671dd9f481e0
ToppCell	droplet-Bladder-nan-24m-Endothelial-endothelial_cell\|Bladder / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FLT1 RELN DGKB DGKG MMRN1 CA4	7.52e-06	196	106	6	04dfef1bd4ebb0e9469ae80024dc177e469a2560
ToppCell	COPD-Endothelial-VE_Capillary_B\|Endothelial / Disease state, Lineage and Cell class	UNC13B FLT1 CDK14 IL18R1 NAV1 CA4	7.74e-06	197	106	6	30dbc05ea66892d2e18ff375ffa86d1db7bc4083
ToppCell	LA-09._Endothelium_I\|LA / Chamber and Cluster_Paper	FLT1 MYRIP BCL2L1 MMRN1 EML1 CA4	7.74e-06	197	106	6	ab6d1ab586a188597a39854ef980b8955ebcc645
ToppCell	droplet-Bladder-nan-24m-Endothelial-endothelial_cell\|Bladder / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FLT1 RELN DGKB DGKG MMRN1 CA4	7.74e-06	197	106	6	488e85991c5e668afb7672942726d9295b8fc7d8
ToppCell	Parenchymal-NucSeq-Endothelial\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	FLT1 RELN IL18R1 MMRN1 NAV1 CA4	8.20e-06	199	106	6	a4a9a1c2a34b5a8318a55d1211d6c8661ca9793e
ToppCell	Control_saline-Endothelial-Endothelial-Vein\|Control_saline / Treatment groups by lineage, cell group, cell type	FLT1 SPTAN1 MYRIP MMRN1 IGF2 UNC13C	8.44e-06	200	106	6	e5f876910bc8cb390d9b46a48d9b6d4d57235551
ToppCell	droplet-Heart-HEART_(ALL_4:4:4:1:1)-30m-Mesenchymal-fibroblast\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DPT PNLIP MYRIP ERRFI1 MMP2	1.99e-05	138	106	5	e2659949944bdf39b23c7275e380a7a937e2726c
ToppCell	droplet-Heart-HEART_(ALL_4:4:4:1:1)-30m-Mesenchymal-fibroblast_of_cardiac_tissue\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DPT PNLIP MYRIP ERRFI1 MMP2	1.99e-05	138	106	5	d5342383c5e52b92c39d7afe76560501be3ea5cd
ToppCell	COVID-19-kidney-Technical/muscle_(Mes)\|COVID-19 / Disease (COVID-19 only), tissue and cell type	MYT1L RELN DGKB SNTG1 UNC13C	2.79e-05	148	106	5	d6ac5972267254651dfbe16bb4e9a62228093cc7
ToppCell	COVID-19-kidney-Technical/muscle_(Imm)\|COVID-19 / Disease (COVID-19 only), tissue and cell type	MYT1L RELN KLHL10 SNTG1 UNC13C	2.98e-05	150	106	5	0205318a870e091add66ee4305747dda9f51510d
ToppCell	PBMC-Severe-Myeloid-cDC-cDC-cDC_4\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	NRG1 OLFML2B MAP3K20 PLBD2 KCTD6	3.70e-05	157	106	5	f896997490bb2eec598c6581f161220e70f9a991
ToppCell	PBMC-Severe-Myeloid-cDC-cDC-cDC_4\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)	NRG1 OLFML2B MAP3K20 PLBD2 KCTD6	3.70e-05	157	106	5	14a8516346a89a89f1119b744625bd9844a74a03
ToppCell	facs-Limb_Muscle-Muscle_Diaphragm-18m-Endothelial-endothelial_cell\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FLT1 RELN BCL2L1 MMRN1 CA4	3.70e-05	157	106	5	b6ecf1d8c6a465ff31cbc181e00ea88b76b38e19
ToppCell	facs-Limb_Muscle-Muscle_Diaphragm-18m-Endothelial\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FLT1 RELN BCL2L1 MMRN1 CA4	3.70e-05	157	106	5	01ad5cbaf91010e79216e1fb37b7b890618c5f28
ToppCell	3'-GW_trimst-1-LargeIntestine-Mesenchymal-fibroblastic-Stromal_2_(CH25H+)\|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	NRG1 SHROOM2 IL18R1 IGF2BP2-AS1 MMP2	4.05e-05	160	106	5	6215ac6123a295f3c2f033786602a57b2e2e1177
ToppCell	PND07-Endothelial-Endothelial_lymphatic-Lymphatic_EC-LEC-LEC_prolif\|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	RELN DUOX2 MMRN1 YTHDF1 IGF2	4.69e-05	165	106	5	50a8513d8d2630861499393a7f102b35366bad37
ToppCell	facs-Lung-Endomucin_-18m-Endothelial-vein_endothelial_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FLT1 SLC43A3 BST1 SNTG1 ACAP2	5.11e-05	168	106	5	3bddf411a60137a8883fc9e77586e4719b0d6067
ToppCell	NS-critical-d_16-33-Epithelial-Ionocyte\|d_16-33 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	MUC19 ATP6V0A4 FOXI2 UNC13C FOXI1	5.11e-05	168	106	5	6a233045638cb83dab64789b996b7598c325001e
ToppCell	facs-Lung-Endomucin_-18m-Endothelial-Vein_endothelial_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FLT1 SLC43A3 BST1 SNTG1 ACAP2	5.11e-05	168	106	5	b6d948857ee652351ddbe383b75fdd1721cd8721
ToppCell	Primary_Motor_Cortex_(M1)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_D_(IT_RORB_THEMIS_LINC00507)_4-Exc_L3-5_THEMIS_UBE2F\|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	NRG1 NPY2R LIPA OTOGL FOLH1B	5.11e-05	168	106	5	bfa1491e8d433933003778b274710d3a16d973cb
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Proximal_Tubule_Epithelial_Cell_Segment_1_/_Segment_2\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	DGKB GRAMD1B OTOGL ERRFI1 SLC27A2	5.56e-05	171	106	5	f5014e3c387fe3118944af392abe10d6b9b0abab
ToppCell	droplet-Thymus-nan-3m-Myeloid\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PLBD1 CDK14 HEPH NAV1 MMP2	5.56e-05	171	106	5	25493a4a7b636920e2cfd984542cc500709c9dcf
ToppCell	droplet-Thymus-nan-3m-Myeloid-professional_antigen_presenting_cell\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PLBD1 CDK14 HEPH NAV1 MMP2	5.56e-05	171	106	5	508b41e3ad2638f9dd546d251b13ff60fc8c3207
ToppCell	nucseq-Epithelial-Epithelial_Neuro-Secretory-PNEC\|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	MYT1L NRG1 DGKB SNTG1 CTSV	5.56e-05	171	106	5	f4321133190a3df9d31f5d4021a464d3840145f1
ToppCell	nucseq-Epithelial-Epithelial_Neuro-Secretory-PNEC-PNEC\|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	MYT1L NRG1 DGKB SNTG1 CTSV	5.56e-05	171	106	5	ed4fb6c84579d99df33de5f8f928c3cd2f3d3d72
ToppCell	primary_auditory_cortex_(A1C)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_D_(IT_RORB_THEMIS_LINC00507)_4-Exc_L4-5_RORB_LCN15\|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	NRG1 NPY2R LIPA FOLH1B UNC13C	5.71e-05	172	106	5	92e76cbf4807704790f42cf2507e92f85cd3bc92
ToppCell	nucseq-Epithelial-Epithelial_Neuro-Secretory\|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	MYT1L NRG1 DGKB SNTG1 CTSV	5.71e-05	172	106	5	d0cdedd734406988a9a93d7300c7b1a8b4b45c38
ToppCell	Mid-temporal_gyrus_(MTG)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_D_(IT_RORB_THEMIS_LINC00507)_4\|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	NRG1 NPY2R LIPA FOLH1B UNC13C	5.87e-05	173	106	5	ee972d9cc68755926512fd3bbe1267098c67cd94
ToppCell	facs-Mammary_Gland-Mammary_Gland-18m-Endothelial-endothelial_cell\|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FLT1 ACACB MMRN1 IGF2 KLHL30	5.87e-05	173	106	5	a2c1ef3f4d7e9f68fc77ee7c42a4727bdea5da94
ToppCell	facs-Mammary_Gland-Mammary_Gland-18m-Endothelial\|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FLT1 ACACB MMRN1 IGF2 KLHL30	5.87e-05	173	106	5	4830136f1f1976e00ac9af9062a531ac42533041
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell-Distal_Convoluted_Tubule_Cell_Type_1\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	ACACB BCL2L1 CDK14 GRAMD1B ATP6V0A4	5.87e-05	173	106	5	4bc6d93716f093b460c8b047199db8cab5fea720
ToppCell	facs-Mammary_Gland-Mammary_Gland-18m-Endothelial-nan\|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FLT1 ACACB MMRN1 IGF2 KLHL30	5.87e-05	173	106	5	0b79e2a4fd19d524c24b69a6b524ffc6affdabe5
ToppCell	droplet-Thymus-nan-3m-Myeloid-Macrophage\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PLBD1 CDK14 HEPH NAV1 MMP2	5.87e-05	173	106	5	63f03abca84ae021ff34ff34537838aa8a1ccd11
ToppCell	10x5'-GI_small-bowel-Myeloid_Monocytic-Classical_monocytes\|GI_small-bowel / Manually curated celltypes from each tissue	NRG1 PLBD1 FLT1 MAP3K20 BST1	6.04e-05	174	106	5	05d54a36772f096047521e16a89cc42ae48d2a1d
ToppCell	Posterior_cortex-Macroglia-POLYDENDROCYTE-P3\|Posterior_cortex / BrainAtlas - Mouse McCarroll V32	KLHL10 PNLIP FOXI2 MMP2	6.09e-05	89	106	4	9e7041ab9409028007fefe53db6d1048eafae93b
ToppCell	Posterior_cortex-Macroglia-POLYDENDROCYTE-P3-Tnr-Polydendrocyte.Tnr.Cspg5_(Cspg5)-\|Posterior_cortex / BrainAtlas - Mouse McCarroll V32	KLHL10 PNLIP FOXI2 MMP2	6.09e-05	89	106	4	436e1229ee28517c11dfe0a5d1cdad3477419e00
ToppCell	Posterior_cortex-Macroglia-POLYDENDROCYTE-P3-Tnr\|Posterior_cortex / BrainAtlas - Mouse McCarroll V32	KLHL10 PNLIP FOXI2 MMP2	6.09e-05	89	106	4	e7abf4af18d63c9384d25365a827e85a9adee964
ToppCell	Posterior_cortex-Macroglia-POLYDENDROCYTE-P3-Tnr-Polydendrocyte.Tnr.Cspg5_(Cspg5)\|Posterior_cortex / BrainAtlas - Mouse McCarroll V32	KLHL10 PNLIP FOXI2 MMP2	6.09e-05	89	106	4	4e5f4c0404968422703c248488e6b2ee8737dc00
ToppCell	E18.5-Endothelial-Endothelial_blood-vessel-Macrovascular_EC-VEC-VEC_mature\|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	NRG1 FLT1 MYRIP DUOX2 MMP2	6.20e-05	175	106	5	2e54961846c65b185d9bd6e305dd81205579d890
ToppCell	E16.5-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_airway-SCMF-SCMF_mature\|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	ACACA OLFML2B HECTD4 GRAMD1B SYNJ1	6.20e-05	175	106	5	1d8aab491dcc27ea5dbfb6462d18ee280b21a05e
ToppCell	facs-Heart-RV-18m-Mesenchymal-smooth_muscle_cell\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DGKB DGKG SERPINI1 CFAP126 KLHL30	6.20e-05	175	106	5	d8e385320f554d974538b7cdc4f8e4767f1455f2
ToppCell	E18.5-Endothelial-Endothelial_blood-vessel-Macrovascular_EC-VEC\|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	NRG1 FLT1 MYRIP DUOX2 MMP2	6.20e-05	175	106	5	efa6a05f7417d46141b6e635f258c126b7a03aa1
ToppCell	E16.5-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_airway-SCMF\|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	ACACA OLFML2B HECTD4 GRAMD1B SYNJ1	6.20e-05	175	106	5	427a7ee92fe16a90625946492062d37aa0f7235b
ToppCell	facs-Heart-RV-18m-Mesenchymal-smooth_muscle_cell\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DGKB DGKG SERPINI1 CFAP126 KLHL30	6.20e-05	175	106	5	cf15465855602ba135752c18755e3e058dbd42ec
ToppCell	B_cells-pDCs\|B_cells / Immune cells in Kidney/Urine in Lupus Nephritis	IL18R1 MMRN1 GRAMD1B BST1 CTSV	6.37e-05	176	106	5	ce757de9e09a225f3f96433f103f43619b0e0dda
ToppCell	facs-Trachea-18m-Mesenchymal-myofibroblast-tracheobronchial_smooth_muscle_cell-smooth_muscle_cell_of_trachea_l39\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	MAP3K20 DGKB DGKG SERPINI1 KLHL30	6.55e-05	177	106	5	928118b0ed120ec01c7d753ce523ab609ac24e5f
ToppCell	PND28-Endothelial-Endothelial_blood-vessel-Macrovascular_EC\|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	FLT1 MYRIP SLC43A3 IGF2 BST1	6.55e-05	177	106	5	6f6cf93893daac6ae228df36219ee3acf8de8f97
ToppCell	10x3'2.3-week_12-13-Mesenchymal_myocytic-stroma-muscle_stem_cell\|week_12-13 / cell types per 3 fetal stages;per 3',per 5'	DPT OLFML2B DUOX2 SHROOM2 IGF2	6.72e-05	178	106	5	8f31b3fac51591f7f2bcb898c07708b3e9f93a16
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell-Intercalated_Cell_Type_B\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	MYRIP DGKB ATP6V0A4 UNC13C FOXI1	6.72e-05	178	106	5	51d2188406f04329311b2efd1108fc36617a860e
ToppCell	NS-critical-LOC-Epithelial-Ionocyte\|LOC / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	MYRIP ATP6V0A4 FOXI2 UNC13C FOXI1	6.90e-05	179	106	5	65a96bee7bc28f5bfc20f0fd92bcc0ab2eb5e06c
ToppCell	10x3'2.3-week_12-13-Mesenchymal_myocytic\|week_12-13 / cell types per 3 fetal stages;per 3',per 5'	DPT OLFML2B DUOX2 SHROOM2 IGF2	7.27e-05	181	106	5	47dce04db3392333eb2f7b9b24c32e6740d2d02f
ToppCell	10x3'2.3-week_12-13-Mesenchymal_myocytic-stroma\|week_12-13 / cell types per 3 fetal stages;per 3',per 5'	DPT OLFML2B DUOX2 SHROOM2 IGF2	7.27e-05	181	106	5	19103221c3a5a16b16378348004b2c50caee4f01
ToppCell	5'-GW_trimst-2-LymphNode-Mesenchymal-Pericytes-Contractile_pericyte_(PLN+)\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	MAP3K20 DGKB DGKG SERPINI1 KLHL30	7.27e-05	181	106	5	59527ad218e49386b04cabb97d53d2ed55a35961
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	ACACB BCL2L1 CDK14 GRAMD1B ATP6V0A4	7.27e-05	181	106	5	e0abf2707d9e0aa942c657eef7d2cbcd02f060dd
ToppCell	RV\|World / Chamber and Cluster_Paper	ACACB DGKG GRAMD1B NAV1 MMP2	7.27e-05	181	106	5	bbe1e6e59d8889bd37d6e8303116cbdcafca7236
ToppCell	3'-GW_trimst-2-LargeIntestine-Mesenchymal-myocytic-SMC_(PART1/CAPN3+)\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	SERPINB7 MAP3K20 DGKG HEPH SVIL	7.27e-05	181	106	5	beb2771820956be8b190c0088ae3c4efdb53c897
ToppCell	droplet-Heart-HEART_(ALL_MINUS_AORTA)-30m-Mesenchymal-coronary_vascular_endothelial_cell\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CCDC174 DGKB CFAP126 DMKN EML1	7.27e-05	181	106	5	709e9c7a60d5f98635b99895ce30bb87a9f7376d
ToppCell	droplet-Pancreas-Exocrine-18m-Endothelial\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FLT1 SLC43A3 HEPH MMRN1 CA4	7.47e-05	182	106	5	3b4dbf61ca0fe50efe05449815630e301cb76630
ToppCell	droplet-Pancreas-Exocrine-18m-Endothelial-endothelial_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FLT1 SLC43A3 HEPH MMRN1 CA4	7.47e-05	182	106	5	ab5761bf9af439231cd0f487b6467e372672a517
ToppCell	facs-Heart-LA-3m-Mesenchymal-smooth_muscle_cell\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MAP3K20 DGKB DGKG SERPINI1 ERRFI1	7.66e-05	183	106	5	8d45dff06a199b1369576657f7f9dc0249c5f841
ToppCell	facs-Heart-LA-3m-Mesenchymal-smooth_muscle_cell\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MAP3K20 DGKB DGKG SERPINI1 ERRFI1	7.66e-05	183	106	5	421265fa15d5a028cb567bb0904e670473ef102b
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic-thymocyte\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	RELN DGKB TRANK1 OTOGL UNC13C	7.86e-05	184	106	5	2cbed6462fea2622871bb7e49b0df3d984239281
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	RELN DGKB TRANK1 OTOGL UNC13C	7.86e-05	184	106	5	ea7a7e2bac46d4d2c31a5d576b38a032b5335062
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic-proliferating_thymocyte;_DN_to_DP_transition,_dividing_(some_are_Cd8+/_Cd4+,_some_undergoing_VDJ_recombination)\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	RELN DGKB TRANK1 OTOGL UNC13C	7.86e-05	184	106	5	2b19a8c5f823e00812908b23e66bb4e563278aff
ToppCell	PCW_13-14-Mesenchymal-Mesenchymal_fibroblastic-mes_Arw_fibro_(16)\|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung	DPT RELN SERPINI1 SVIL MMP2	8.06e-05	185	106	5	7dcdc009c5681ee05dd18968f7e85c3403fe34af
ToppCell	metastatic_Lymph_Node-Fibroblasts-COL14A1+_matrix_FBs\|metastatic_Lymph_Node / Location, Cell class and cell subclass	DPT HEPH IGF2 MMP2 PRG4	8.06e-05	185	106	5	506eee2c1b6e8acec3aa8b2c66868010006c4c14
ToppCell	droplet-Heart-4Chambers-21m-Mesenchymal-smooth_muscle_cell\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MAP3K20 DGKB SERPINI1 KLHL30 ERRFI1	8.06e-05	185	106	5	30df02fbe2828e3c4f3e5c4cda855e74fb31be39
ToppCell	droplet-Bladder-nan-24m-Endothelial-nan\|Bladder / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FLT1 RELN SLC43A3 MMRN1 CA4	8.06e-05	185	106	5	90caab8d9361a541c5d5121c97c3f1cdffeeae4a
ToppCell	droplet-Heart-nan-18m-Endothelial\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	UNC13B FLT1 SPTAN1 BCL2L1 CA4	8.06e-05	185	106	5	a32d5cb596ebac80eb1ac301055e65d420879ec8
ToppCell	Control-Endothelial_cells-Endothelial_cells_(other)\|Control / group, cell type (main and fine annotations)	FLT1 IL18R1 NAV1 EML1 CA4	8.27e-05	186	106	5	c6075fe84226b370c5139066793844ad33ae2db1
ToppCell	facs-Heart-LA-24m-Mesenchymal\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DPT PNLIP OLFML2B ERRFI1 MMP2	8.27e-05	186	106	5	ed0a91f47e77fe21d4c7678d0f2a7c5f97d63dda
ToppCell	10x3'2.3-week_12-13-Mesenchymal_adipo\|week_12-13 / cell types per 3 fetal stages;per 3',per 5'	OLFML2B IGF2 ERRFI1 UNC13C MMP2	8.48e-05	187	106	5	f1d0fc625e0e7881b3f290742fd7148d995eb71e
ToppCell	10x3'2.3-week_12-13-Mesenchymal_adipo-stroma\|week_12-13 / cell types per 3 fetal stages;per 3',per 5'	OLFML2B IGF2 ERRFI1 UNC13C MMP2	8.48e-05	187	106	5	02e7246ef5ad41773d14426254e139b156d45c1d
Disease	celiac disease	ACACA IL18R1 TLR8 IGF2 ERRFI1 NAV1	5.18e-06	126	102	6	EFO_0001060
Disease	Mandibular Diseases	ZMPSTE24 MMP2	1.18e-05	2	102	2	C0024689
Disease	familial encephalopathy with neuroserpin inclusion bodies (is_implicated_in)	SERPINB7 SERPINI1	1.18e-05	2	102	2	DOID:0050831 (is_implicated_in)
Disease	RENAL TUBULAR ACIDOSIS, DISTAL, AUTOSOMAL RECESSIVE	ATP6V0A4 FOXI1	3.54e-05	3	102	2	C1864498
Disease	muscular disease (implicated_via_orthology)	ACACA ACACB	1.18e-04	5	102	2	DOID:0080000 (implicated_via_orthology)
Disease	Cerebral Hemorrhage	FLT1 BCL2L1 MMP2	1.23e-04	28	102	3	C2937358
Disease	osteoarthritis (is_marker_for)	FLT1 IGF2 MMP2	2.42e-04	35	102	3	DOID:8398 (is_marker_for)
Disease	chronic obstructive pulmonary disease	FLT1 MAP3K20 DGKB DGKG BTBD1 IL18R1 PRDM11 SVIL NAV1	6.44e-04	688	102	9	EFO_0000341
Disease	sleep apnea measurement	DENND4C HOOK1 SNTG1 FOXI2	7.16e-04	116	102	4	EFO_0007817
Disease	Emery-Dreifuss muscular dystrophy (implicated_via_orthology)	ZMPSTE24 HOOK1	7.64e-04	12	102	2	DOID:11726 (implicated_via_orthology)
Disease	FVC change measurement, response to placebo	RELN DGKB	9.00e-04	13	102	2	EFO_0008344, EFO_0010339
Disease	vascular dementia (biomarker_via_orthology)	FLT1 MMP2	1.05e-03	14	102	2	DOID:8725 (biomarker_via_orthology)
Disease	schizophrenia (biomarker_via_orthology)	NRG1 ASH2L	1.21e-03	15	102	2	DOID:5419 (biomarker_via_orthology)
Disease	hepcidin:transferrin saturation ratio	KCTD6 FOXI2	1.21e-03	15	102	2	EFO_0007902
Disease	Malignant neoplasm of breast	NRG1 FLT1 ABL1 STARD8 SPTAN1 GSDMB DGKG SHROOM2 HOOK1 OTOGL MMP2	1.23e-03	1074	102	11	C0006142
Disease	ocular hypertension (biomarker_via_orthology)	BCL2L1 MMP2	1.56e-03	17	102	2	DOID:9282 (biomarker_via_orthology)
Disease	eicosapentaenoate EPA; 20:5n3 measurement	NRG1 CDK14	1.56e-03	17	102	2	EFO_0021049
Disease	obstructive sleep apnea	NRG1 DGKG SNTG1	1.57e-03	66	102	3	EFO_0003918
Disease	mitochondrial heteroplasmy measurement	ATAD5 NDUFS4 UNC13C	1.78e-03	69	102	3	EFO_0600008
Disease	asthma, age at onset	SERPINB7 GSDMB IL18R1	1.86e-03	70	102	3	EFO_0004847, MONDO_0004979
Disease	allergic disease, age at onset	SERPINB7 GSDMB IL18R1	1.93e-03	71	102	3	EFO_0004847, MONDO_0005271
Disease	Alzheimer's disease (is_marker_for)	NRG1 RELN BCL2L1 IGF2 MMP2	2.02e-03	257	102	5	DOID:10652 (is_marker_for)
Disease	temporal lobe epilepsy (is_marker_for)	RELN NPY2R	2.16e-03	20	102	2	DOID:3328 (is_marker_for)
Disease	Fetal Growth Retardation	IGF2 MMP2	2.16e-03	20	102	2	C0015934
Disease	chronic myeloid leukemia (is_implicated_in)	ABL1 BCL2L1	2.38e-03	21	102	2	DOID:8552 (is_implicated_in)
Disease	serum IgM measurement	GSDMB GRAMD1B	2.61e-03	22	102	2	EFO_0004993
Disease	neuroimaging measurement, brain volume measurement	BCL2L1 DTWD2 EML1 TUBD1 SCAI	3.20e-03	286	102	5	EFO_0004346, EFO_0006930

Protein segments in the cluster

Peptide	Gene	Start	Entry
KYGRNDFSWTNGKVT	ATAD5	1671	Q96QE3
FWKRASIQYSKDSSG	BST1	171	Q10588
FEGANSNNSKYWLVK	CTSV	286	O60911
KSDRQYKFWSQISQG	GSDMB	171	Q8TAX9
KLSQKGYSWSQFSDV	BCL2L1	16	Q07817
FRSNKNVWGYFSVAA	ACACA	531	Q13085
SIFSKKEGSDRQWNY	DPT	61	Q07507
FTLYSSKNLRQAWNK	CDK14	371	O94921
GYLFKRASNAFKTWN	ACAP2	271	Q15057
WDNFYKFSNRAKNLL	ADCY10	1436	Q96PN6
WSQAKDIFYKNSLFR	DTWD2	181	Q8NBA8
RSGGKNSKKSQSWYN	GRAMD1B	71	Q3KR37
FSYSWRSKKGTKFHQ	ASH2L	456	Q9UBL3
AFNWSKNKKTYIFAG	MMP2	571	P08253
FAFGSKDKNFQWANT	RANBP2	2861	P49792
FGAWGKYKNSEINFS	PPM1K	346	Q8N3J5
QSFFGLWYRGKAESS	RILP	341	Q96NA2
KSSTQFGSYKQAEWR	RIC1	61	Q4ADV7
GWMNSNYRKAFLSAF	NPY2R	326	P49146
SEYSSLRFKWFKNGN	NRG1	61	Q02297
WKTSDLYQLFSAFGN	PARN	456	O95453
GLGNFAFYNSKAKRW	KLHL30	291	Q0D2K2
ELNFRSSKNVWGYFS	ACACB	671	O00763
KADKSLSYNSRFWKN	IL18R1	501	Q13478
ARKEGSSFAYISWKF	NGLY1	541	Q96IV0
KFYLDTGDASNFARW	PNLIP	341	P16233
SWYRDITSNKKFFSL	NAA60	41	Q9H7X0
DYQKSNFETTRGKNW	MMRN1	196	Q13201
RYWFENTRNGLFSKK	DUOX2	516	Q9NRD8
FPFYKRSKAGWQNSI	FOXI2	136	Q6ZQN5
QAVKSGKFQAYDWGS	LIPF	296	P07098
NSIFFFKGNAYWKVV	MMP21	516	Q8N119
STWSKGAYKSFNGRI	MUC19	481	Q7Z5P9
RSFFAGSQKYGAVWT	GANC	571	Q8TET4
RARYTKNWETNKFSG	FOLH1B	226	Q9HBA9
RWTDGNLYKAKFISS	KDM4B	986	O94953
SVSQYAAKNQKFFQW	LRP2BP	16	Q9P2M1
QSGFRKDSSLYKAPW	HECTD4	2601	Q9Y4D8
GKRWADIFSKYNSGT	PLBD1	336	Q6P4A8
SLYFSKAGKRQLVSW	RELN	1106	P78509
SYVSANNKKNSFWGS	IGF2BP2-AS1	31	Q96M15
KNKLWYFEFGTSETF	DGKG	611	P49619
NYWAKRRNSTFSGFE	EBLN1	306	P0CF75
ALFTSGWNNTEKKVY	KLHL10	66	Q6JEL2
FFSGYDKKQTWTVQN	CA4	71	P22748
NFDTFWKNFKSKLGF	DMKN	356	Q6E0U4
YNKVSTVFWKSGNAL	EIF3A	276	Q14152
TNFSKLISNGYKDEW	C7orf57	211	Q8NEG2
YNWQATKASLKERFA	BTBD1	46	Q9H0C5
GKFFQYDTWKQSTQR	IGF2	111	P01344
NSRMKNKFWYFEFGT	DGKB	611	Q9Y6T7
YVSWRNFNSEKKSSL	DENND4C	1786	Q5VZ89
LAYNKFSIKSDVWAF	ABL1	411	P00519
SFWKRKNETRSQGYN	ANKRD7	6	Q92527
EKAFSSKYLQNWSPT	CFAP126	11	Q5VTH2
SFGSVYRAKWISQDK	MAP3K20	26	Q9NYL2
SLLEGISNYFTKWNK	KCTD6	151	Q8NC69
RGKEFSFGYWSKRQS	CCDC174	366	Q6PII3
KKSFFQRFGLDKWSS	GLB1L2	526	Q8IW92
YFWTLEGSSLNKKQG	EML1	396	O00423
NFPFYNKSKAGWQNS	FOXI1	156	Q12951
VSAWYNKSLAFQKLG	HOOK1	666	Q9UJC3
KSRLYQLDKSTFSFW	ZMPSTE24	66	O75844
SSGKCFRIYSKDFWN	DHX40	401	Q8IX18
KSKSYGANFSWNKRT	NDUFS4	156	O43181
FFLENKSTYQLWKAG	OTOGL	1026	Q3ZCN5
FSKFNFSKSNALETW	P2RX6	206	O15547
YWNNSAKSLFPKTSL	NXPE1	46	Q8N323
NCFLQWGFKTYRTSS	MTERF3	51	Q96E29
INAVYFKGNWKSQFR	SERPINI1	181	Q99574
KSWVYELRSSFNKAF	NAV1	1211	Q8NEY1
KDFWKLLGGQTSYQS	SVIL	1531	O95425
KVLNSGNFYFAWSAS	SYNJ1	121	O43426
LWRYKFSQLKGSSDD	SNTG1	431	Q9NSN8
KFSASQFWDDCRKYN	SLC27A2	291	O14975
FFQKSSSRIGGTYWK	HEPH	416	Q9BQS7
GFFSWLIVDKNNRYK	PRDM11	191	Q9NQV5
GTFAEYQASWKEQRK	SHROOM2	871	Q13796
AGQKQELRSFWSYAF	SLC43A3	261	Q8NBI5
ENFKQGRWSNSYKLP	OLFML2B	546	Q68BL8
KTYWSSRSEFKNNFL	ERRFI1	31	Q9UJM3
GKTFFFKDSQYWRFT	PRG4	1206	Q92954
FLSAGFYRAKNWAAT	STARD8	171	Q92502
SAHLTFNKFWRRYGK	CHST12	211	Q9NRB3
AFNVWKTQRAFSKYE	TUBD1	376	Q9UJT1
AKSWNFKTAFYLALQ	TLR8	951	Q9NR97
FRKNNYKWVAASSKS	ZC3H3	306	Q8IXZ2
SGSFYSWQKAKREQG	ZNF182	11	P17025
KSNTWSPKYNETFQF	UNC13C	2106	Q8NB66
FAKKASAFNSWFENA	SPTAN1	2096	Q13813
KNSSYFADWFPDNVK	TUBB8B	336	A6NNZ2
HGKAFNWSSALTYKR	ZNF728	206	P0DKX0
FGRTFDVYTKLWKFQ	SCAI	91	Q8N9R8
KQKQFSSSGEWYKRG	SLU7	91	O95391
LVNAVYFKGKWQSAF	SERPINB7	171	O75635
YFKGKWQSAFTKSET	SERPINB7	176	O75635
KSKSNNWAPKYNETF	UNC13B	1481	O14795
WNLASNKLTFLNSYK	ATP6V0A4	526	Q9HBG4
FSNEKYQKGFSLWAV	TRAM1	241	Q15629
TWADIFKRFNSGTYN	PLBD2	361	Q8NHP8
KSNAFFSLGKWNEAF	TRANK1	21	O15050
WDSRKGFIISNATYK	FLT1	186	P17948
TFGKVQGNSDLYWKA	TRPM4	1046	Q8TD43
SYNPKEFEWNLKSGR	YTHDF1	376	Q9BYJ9
KFQKFQAFDWGSSAK	LIPA	301	P38571
QSLEWFYNNVKSRFK	MYRIP	116	Q8NFW9
KDGYLNGSQFSWKSV	MYT1L	986	Q9UL68