Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	DNA-binding transcription factor activity, RNA polymerase II-specific	ZNF675 ZBTB49 ZNF19 ZNF20 ZNF836 ZBTB16 ZNF146 ZNF473 NFIX GLI4 ZNF696 ZNF83 ZSCAN23 ZNF791 ZNF583 NOTCH2 ZBTB14 ZNF829 ZNF260	9.91e-06	1412	88	19	GO:0000981
GeneOntologyMolecularFunction	extracellular matrix structural constituent	FBN2 VWF MUC17 MATN1 LAMA5 AGRN FBN3	1.96e-05	188	88	7	GO:0005201
GeneOntologyMolecularFunction	RNA polymerase II transcription regulatory region sequence-specific DNA binding	ZNF675 ZBTB49 ZNF19 ZNF20 ZNF836 ZBTB16 ZNF146 ZNF473 NFIX GLI4 ZNF696 ZNF83 ZSCAN23 ZNF791 ZNF583 ZBTB14 ZNF829 ZNF260	5.60e-05	1459	88	18	GO:0000977
GeneOntologyMolecularFunction	integrin binding	VWF LAMA5 ADAM2 ITGB5 GFRA1 SVEP1	1.24e-04	175	88	6	GO:0005178
GeneOntologyMolecularFunction	cis-regulatory region sequence-specific DNA binding	ZNF675 ZBTB49 ZNF836 ZBTB16 ZNF146 ZNF473 NFIX GLI4 ZNF83 ZSCAN23 ZNF583 NOTCH2 ZBTB14 ZNF829 ZNF260	4.11e-04	1271	88	15	GO:0000987
GeneOntologyMolecularFunction	calcium ion binding	STAB2 FBN2 SCUBE2 EGF MATN1 C1R AGRN F9 FBN3 SVEP1 NOTCH2	4.44e-04	749	88	11	GO:0005509
GeneOntologyMolecularFunction	hydrolase activity, hydrolyzing N-glycosyl compounds	MAN2A2 TLR2 IL1RL1	7.81e-04	41	88	3	GO:0016799
GeneOntologyMolecularFunction	RNA polymerase II cis-regulatory region sequence-specific DNA binding	ZNF675 ZBTB49 ZNF836 ZBTB16 ZNF146 ZNF473 NFIX GLI4 ZNF83 ZSCAN23 ZNF583 ZBTB14 ZNF829 ZNF260	1.04e-03	1244	88	14	GO:0000978
GeneOntologyBiologicalProcess	positive regulation of ossification	ZBTB16 FBN2 SCUBE2 LRP6 LTF ALOX5	3.75e-07	66	88	6	GO:0045778
GeneOntologyBiologicalProcess	regulation of ossification	ZBTB16 FBN2 SCUBE2 MATN1 LRP6 LTF ALOX5	3.17e-06	147	88	7	GO:0030278
GeneOntologyBiologicalProcess	bone development	ZBTB16 SCUBE2 NFIX MATN1 LRP6 LRRK1 LTF NOTCH2	1.72e-05	264	88	8	GO:0060348
GeneOntologyBiologicalProcess	neuron projection development	NTN4 KANK1 MYCBP2 PLXNC1 UNC5B NFIX MTR LAMA5 LRP6 LAMC3 ADGRF1 AGRN SLITRK1 VPS13B GFRA1 NOTCH2 OTOG	2.61e-05	1285	88	17	GO:0031175
GeneOntologyBiologicalProcess	neuron development	NTN4 KANK1 MYCBP2 PLXNC1 UNC5B NFIX MTR LAMA5 LRP6 LAMC3 MFRP ADGRF1 AGRN SLITRK1 VPS13B GFRA1 NOTCH2 OTOG	3.81e-05	1463	88	18	GO:0048666
GeneOntologyBiologicalProcess	axon development	NTN4 MYCBP2 PLXNC1 UNC5B NFIX MTR LAMA5 LAMC3 AGRN SLITRK1 NOTCH2	8.88e-05	642	88	11	GO:0061564
GeneOntologyBiologicalProcess	osteoclast development	LRRK1 LTF NOTCH2	1.09e-04	22	88	3	GO:0036035
GeneOntologyBiologicalProcess	bone cell development	LRRK1 LTF NOTCH2	1.09e-04	22	88	3	GO:0098751
GeneOntologyBiologicalProcess	axonogenesis	NTN4 MYCBP2 PLXNC1 UNC5B NFIX LAMA5 LAMC3 AGRN SLITRK1 NOTCH2	1.48e-04	566	88	10	GO:0007409
GeneOntologyBiologicalProcess	skeletal system morphogenesis	FBN2 SCUBE2 NFIX MATN1 LAMA5 LRP6 LTF	1.83e-04	277	88	7	GO:0048705
GeneOntologyBiologicalProcess	bone morphogenesis	SCUBE2 NFIX MATN1 LRP6 LTF	1.90e-04	124	88	5	GO:0060349
GeneOntologyBiologicalProcess	axon guidance	NTN4 MYCBP2 UNC5B LAMA5 LAMC3 AGRN NOTCH2	2.18e-04	285	88	7	GO:0007411
GeneOntologyBiologicalProcess	neuron projection guidance	NTN4 MYCBP2 UNC5B LAMA5 LAMC3 AGRN NOTCH2	2.23e-04	286	88	7	GO:0097485
GeneOntologyBiologicalProcess	cardiac septum development	FRS2 LRP6 NOTCH2 ZBTB14 DNAH11	2.73e-04	134	88	5	GO:0003279
GeneOntologyBiologicalProcess	skeletal system development	ZBTB16 FBN2 SCUBE2 NFIX MATN1 LAMA5 LRP6 LRRK1 LTF NOTCH2	2.88e-04	615	88	10	GO:0001501
GeneOntologyBiologicalProcess	regulation of synaptic assembly at neuromuscular junction	MYCBP2 AGRN	3.73e-04	7	88	2	GO:0008582
GeneOntologyBiologicalProcess	myeloid leukocyte differentiation	ZNF675 NFIX TLR2 IL1RL1 LRRK1 LTF NOTCH2	3.77e-04	312	88	7	GO:0002573
GeneOntologyCellularComponent	extracellular matrix	NTN4 ADAM19 FBN2 VWF MUC17 MATN1 LAMA5 LAMC3 AGRN F9 FBN3 SVEP1 OTOG	3.08e-06	656	87	13	GO:0031012
GeneOntologyCellularComponent	external encapsulating structure	NTN4 ADAM19 FBN2 VWF MUC17 MATN1 LAMA5 LAMC3 AGRN F9 FBN3 SVEP1 OTOG	3.19e-06	658	87	13	GO:0030312
GeneOntologyCellularComponent	cell surface	ADAM19 STAB2 VWF SCUBE2 MUC17 TLR2 LRP6 TNFRSF18 ADAM2 IL1RL1 LTF AGRN ITGB5 GFRA1 NOTCH2	4.98e-05	1111	87	15	GO:0009986
GeneOntologyCellularComponent	collagen-containing extracellular matrix	NTN4 ADAM19 FBN2 VWF MUC17 MATN1 LAMA5 LAMC3 AGRN F9	7.02e-05	530	87	10	GO:0062023
GeneOntologyCellularComponent	laminin complex	NTN4 LAMA5	7.54e-04	10	87	2	GO:0043256
Domain	EGF_1	NTN4 ADAM19 STAB2 FBN2 SCUBE2 EGF MUC17 MATN1 LAMA5 LRP6 C1R LAMC3 ADAM2 AGRN ITGB5 F9 FBN3 SVEP1 NOTCH2	5.78e-18	255	87	19	PS00022
Domain	EGF-like_CS	NTN4 ADAM19 STAB2 FBN2 SCUBE2 EGF MUC17 MATN1 LAMA5 LRP6 C1R LAMC3 AGRN ITGB5 F9 FBN3 SVEP1 NOTCH2	1.87e-16	261	87	18	IPR013032
Domain	EGF_2	ADAM19 STAB2 FBN2 SCUBE2 EGF MUC17 MATN1 LAMA5 LRP6 C1R LAMC3 ADAM2 AGRN ITGB5 F9 FBN3 SVEP1 NOTCH2	2.44e-16	265	87	18	PS01186
Domain	EGF-like_dom	ADAM19 STAB2 FBN2 SCUBE2 EGF MUC17 MATN1 LAMA5 LRP6 C1R LAMC3 AGRN F9 FBN3 SVEP1 NOTCH2 OTOG	1.66e-15	249	87	17	IPR000742
Domain	EGF_3	ADAM19 STAB2 FBN2 SCUBE2 EGF MUC17 MATN1 LRP6 C1R ADAM2 AGRN F9 FBN3 SVEP1 NOTCH2 OTOG	1.27e-14	235	87	16	PS50026
Domain	EGF	STAB2 FBN2 SCUBE2 EGF MUC17 MATN1 LAMA5 LRP6 C1R LAMC3 AGRN ITGB5 F9 FBN3 SVEP1 NOTCH2	1.27e-14	235	87	16	SM00181
Domain	EGF_CA	STAB2 FBN2 SCUBE2 EGF MATN1 C1R AGRN F9 FBN3 SVEP1 NOTCH2	1.08e-11	122	87	11	SM00179
Domain	EGF-like_Ca-bd_dom	STAB2 FBN2 SCUBE2 EGF MATN1 C1R AGRN F9 FBN3 SVEP1 NOTCH2	1.29e-11	124	87	11	IPR001881
Domain	EGF	STAB2 SCUBE2 EGF MATN1 LRP6 AGRN ITGB5 F9 FBN3 SVEP1 NOTCH2	1.54e-11	126	87	11	PF00008
Domain	-	ZNF675 ZBTB49 ZNF19 ZNF20 ZNF836 ZBTB16 ZNF146 ZNF473 ZNF45 GLI4 ZNF696 ZNF83 ZSCAN23 ZNF791 ZNF583 ZBTB14 ZNF829 ZNF260	1.81e-09	679	87	18	3.30.160.60
Domain	zf-C2H2	ZNF675 ZBTB49 ZNF19 ZNF20 ZNF836 ZBTB16 ZNF146 ZNF473 ZNF45 GLI4 ZNF696 ZNF83 ZSCAN23 ZNF791 ZNF583 ZBTB14 ZNF829 ZNF260	2.50e-09	693	87	18	PF00096
Domain	Znf_C2H2/integrase_DNA-bd	ZNF675 ZBTB49 ZNF19 ZNF20 ZNF836 ZBTB16 ZNF146 ZNF473 ZNF45 GLI4 ZNF696 ZNF83 ZSCAN23 ZNF791 ZNF583 ZBTB14 ZNF829 ZNF260	2.56e-09	694	87	18	IPR013087
Domain	Growth_fac_rcpt_	NTN4 STAB2 FBN2 SCUBE2 EGF LAMA5 LAMC3 FBN3 SVEP1 NOTCH2	2.85e-09	156	87	10	IPR009030
Domain	EGF_CA	FBN2 SCUBE2 EGF MATN1 C1R FBN3 SVEP1 NOTCH2	6.30e-09	86	87	8	PF07645
Domain	ZINC_FINGER_C2H2_2	ZNF675 ZBTB49 ZNF19 ZNF20 ZNF836 ZBTB16 ZNF146 ZNF473 ZNF45 GLI4 ZNF696 ZNF83 ZSCAN23 ZNF791 ZNF583 ZBTB14 ZNF829 ZNF260	1.42e-08	775	87	18	PS50157
Domain	ZINC_FINGER_C2H2_1	ZNF675 ZBTB49 ZNF19 ZNF20 ZNF836 ZBTB16 ZNF146 ZNF473 ZNF45 GLI4 ZNF696 ZNF83 ZSCAN23 ZNF791 ZNF583 ZBTB14 ZNF829 ZNF260	1.48e-08	777	87	18	PS00028
Domain	EGF_Ca-bd_CS	FBN2 SCUBE2 EGF C1R F9 FBN3 SVEP1 NOTCH2	1.65e-08	97	87	8	IPR018097
Domain	EGF_CA	FBN2 SCUBE2 EGF C1R F9 FBN3 SVEP1 NOTCH2	1.94e-08	99	87	8	PS01187
Domain	ASX_HYDROXYL	FBN2 SCUBE2 EGF C1R F9 FBN3 SVEP1 NOTCH2	2.10e-08	100	87	8	PS00010
Domain	Znf_C2H2-like	ZNF675 ZBTB49 ZNF19 ZNF20 ZNF836 ZBTB16 ZNF146 ZNF473 ZNF45 GLI4 ZNF696 ZNF83 ZSCAN23 ZNF791 ZNF583 ZBTB14 ZNF829 ZNF260	2.15e-08	796	87	18	IPR015880
Domain	Znf_C2H2	ZNF675 ZBTB49 ZNF19 ZNF20 ZNF836 ZBTB16 ZNF146 ZNF473 ZNF45 GLI4 ZNF696 ZNF83 ZSCAN23 ZNF791 ZNF583 ZBTB14 ZNF829 ZNF260	2.55e-08	805	87	18	IPR007087
Domain	ZnF_C2H2	ZNF675 ZBTB49 ZNF19 ZNF20 ZNF836 ZBTB16 ZNF146 ZNF473 ZNF45 GLI4 ZNF696 ZNF83 ZSCAN23 ZNF791 ZNF583 ZBTB14 ZNF829 ZNF260	2.70e-08	808	87	18	SM00355
Domain	EGF-type_Asp/Asn_hydroxyl_site	FBN2 SCUBE2 EGF C1R F9 FBN3 SVEP1 NOTCH2	3.32e-08	106	87	8	IPR000152
Domain	EGF_LAM_2	NTN4 STAB2 LAMA5 LAMC3 AGRN	2.54e-07	30	87	5	PS50027
Domain	EGF_LAM_1	NTN4 STAB2 LAMA5 LAMC3 AGRN	2.54e-07	30	87	5	PS01248
Domain	EGF_Lam	NTN4 STAB2 LAMA5 LAMC3 AGRN	5.68e-07	35	87	5	SM00180
Domain	Laminin_EGF	NTN4 STAB2 LAMA5 LAMC3 AGRN	8.68e-07	38	87	5	IPR002049
Domain	hEGF	FBN2 FBN3 SVEP1 NOTCH2	8.26e-06	28	87	4	PF12661
Domain	zf-C2H2_6	ZNF675 ZBTB49 ZNF20 ZNF836 ZBTB16 ZNF473 ZSCAN23 ZNF791 ZNF260	1.55e-05	314	87	9	PF13912
Domain	-	STAB2 EGF SVEP1	1.57e-05	11	87	3	2.40.155.10
Domain	GFP-like	STAB2 EGF SVEP1	1.57e-05	11	87	3	IPR023413
Domain	Laminin_EGF	NTN4 LAMA5 LAMC3 AGRN	2.06e-05	35	87	4	PF00053
Domain	-	INTS6L VWF MATN1 ITGB5 SVEP1	2.44e-05	74	87	5	3.40.50.410
Domain	VWFA	INTS6L VWF MATN1 ITGB5 SVEP1	4.02e-05	82	87	5	PS50234
Domain	KRAB	ZNF675 ZNF19 ZNF20 ZNF836 ZNF473 ZNF45 ZNF791 ZNF583 ZNF829	4.35e-05	358	87	9	PS50805
Domain	KRAB	ZNF675 ZNF19 ZNF20 ZNF836 ZNF473 ZNF45 ZNF791 ZNF583 ZNF829	4.35e-05	358	87	9	PF01352
Domain	VWA	INTS6L VWF MATN1 ITGB5 SVEP1	4.51e-05	84	87	5	SM00327
Domain	Laminin_N	NTN4 LAMA5 LAMC3	5.23e-05	16	87	3	IPR008211
Domain	LAMININ_NTER	NTN4 LAMA5 LAMC3	5.23e-05	16	87	3	PS51117
Domain	Laminin_N	NTN4 LAMA5 LAMC3	5.23e-05	16	87	3	PF00055
Domain	LamNT	NTN4 LAMA5 LAMC3	5.23e-05	16	87	3	SM00136
Domain	KRAB	ZNF675 ZNF19 ZNF20 ZNF836 ZNF473 ZNF45 ZNF791 ZNF583 ZNF829	5.49e-05	369	87	9	SM00349
Domain	KRAB	ZNF675 ZNF19 ZNF20 ZNF836 ZNF473 ZNF45 ZNF791 ZNF583 ZNF829	5.61e-05	370	87	9	IPR001909
Domain	FBN	FBN2 FBN3	6.42e-05	3	87	2	IPR011398
Domain	HEAT	TNPO1 PPP4R1 TNPO2 PPP4R1L	7.31e-05	48	87	4	PF02985
Domain	CUB	SCUBE2 C1R MFRP OVCH1	7.93e-05	49	87	4	PF00431
Domain	CUB	SCUBE2 C1R MFRP OVCH1	8.59e-05	50	87	4	SM00042
Domain	VWF_A	INTS6L VWF MATN1 ITGB5 SVEP1	9.90e-05	99	87	5	IPR002035
Domain	-	SCUBE2 C1R MFRP OVCH1	1.00e-04	52	87	4	2.60.120.290
Domain	CUB	SCUBE2 C1R MFRP OVCH1	1.08e-04	53	87	4	PS01180
Domain	SEA	MUC17 ADGRF1 AGRN	1.41e-04	22	87	3	PF01390
Domain	CUB_dom	SCUBE2 C1R MFRP OVCH1	1.44e-04	57	87	4	IPR000859
Domain	HEAT	TNPO1 PPP4R1 TNPO2 PPP4R1L	1.54e-04	58	87	4	IPR000357
Domain	SEA	MUC17 ADGRF1 AGRN	1.62e-04	23	87	3	PS50024
Domain	SEA_dom	MUC17 ADGRF1 AGRN	1.62e-04	23	87	3	IPR000082
Domain	EGF_extracell	ADAM19 STAB2 ITGB5 SVEP1	1.76e-04	60	87	4	IPR013111
Domain	EGF_2	ADAM19 STAB2 ITGB5 SVEP1	1.76e-04	60	87	4	PF07974
Domain	cEGF	FBN2 SCUBE2 FBN3	2.35e-04	26	87	3	IPR026823
Domain	cEGF	FBN2 SCUBE2 FBN3	2.35e-04	26	87	3	PF12662
Domain	HEAT_REPEAT	TNPO1 PPP4R1 TNPO2 PPP4R1L	3.19e-04	70	87	4	PS50077
Domain	TB	FBN2 FBN3	4.44e-04	7	87	2	PF00683
Domain	LAMININ_IVA	LAMA5 LAMC3	5.90e-04	8	87	2	PS51115
Domain	Laminin_B	LAMA5 LAMC3	5.90e-04	8	87	2	PF00052
Domain	-	FBN2 FBN3	5.90e-04	8	87	2	3.90.290.10
Domain	LamB	LAMA5 LAMC3	5.90e-04	8	87	2	SM00281
Domain	Laminin_IV	LAMA5 LAMC3	5.90e-04	8	87	2	IPR000034
Domain	TB	FBN2 FBN3	7.56e-04	9	87	2	PS51364
Domain	TB_dom	FBN2 FBN3	7.56e-04	9	87	2	IPR017878
Domain	Galactose-bd-like	NTN4 MYCBP2 LAMA5 LAMC3	9.73e-04	94	87	4	IPR008979
Domain	Ephrin_rec_like	SCUBE2 SVEP1	1.15e-03	11	87	2	PF07699
Domain	EGF_3	STAB2 SCUBE2	1.37e-03	12	87	2	PF12947
Domain	TIL	VWF OTOG	1.37e-03	12	87	2	PF01826
Domain	EGF_dom	STAB2 SCUBE2	1.37e-03	12	87	2	IPR024731
Domain	C8	VWF OTOG	1.37e-03	12	87	2	PF08742
Domain	Unchr_dom_Cys-rich	VWF OTOG	1.62e-03	13	87	2	IPR014853
Domain	C8	VWF OTOG	1.62e-03	13	87	2	SM00832
Domain	SEA	MUC17 AGRN	1.88e-03	14	87	2	SM00200
Domain	IMPORTIN_B_NT	TNPO1 TNPO2	1.88e-03	14	87	2	PS50166
Domain	TIL_dom	VWF OTOG	1.88e-03	14	87	2	IPR002919
Domain	Ldl_recept_b	EGF LRP6	1.88e-03	14	87	2	PF00058
Domain	LDLRB	EGF LRP6	1.88e-03	14	87	2	PS51120
Domain	IBN_N	TNPO1 TNPO2	2.17e-03	15	87	2	PF03810
Domain	-	MUC17 AGRN	2.17e-03	15	87	2	3.30.70.960
Domain	LY	EGF LRP6	2.17e-03	15	87	2	SM00135
Domain	LDLR_classB_rpt	EGF LRP6	2.17e-03	15	87	2	IPR000033
Domain	VWA	VWF MATN1 SVEP1	2.26e-03	56	87	3	PF00092
Domain	VWD	VWF OTOG	2.47e-03	16	87	2	SM00216
Domain	VWF_type-D	VWF OTOG	2.47e-03	16	87	2	IPR001846
Domain	IBN_N	TNPO1 TNPO2	2.47e-03	16	87	2	SM00913
Domain	Disintegrin_CS	ADAM19 ADAM2	2.47e-03	16	87	2	IPR018358
Domain	VWFD	VWF OTOG	2.47e-03	16	87	2	PS51233
Domain	VWD	VWF OTOG	2.47e-03	16	87	2	PF00094
Domain	Importin-beta_N	TNPO1 TNPO2	2.79e-03	17	87	2	IPR001494
Domain	ADAM_CR	ADAM19 ADAM2	3.13e-03	18	87	2	PF08516
Domain	VWC_out	VWF OTOG	3.48e-03	19	87	2	SM00215
Domain	-	ADAM19 ADAM2	3.86e-03	20	87	2	4.10.70.10
Domain	Disintegrin	ADAM19 ADAM2	4.25e-03	21	87	2	PF00200
Domain	DISIN	ADAM19 ADAM2	4.25e-03	21	87	2	SM00050
Domain	TIR	TLR2 IL1RL1	4.25e-03	21	87	2	SM00255
Pathway	REACTOME_EXTRACELLULAR_MATRIX_ORGANIZATION	NTN4 ADAM19 FBN2 VWF MATN1 LAMA5 LAMC3 AGRN ITGB5 FBN3	1.21e-06	300	66	10	M610
Pathway	REACTOME_NON_INTEGRIN_MEMBRANE_ECM_INTERACTIONS	NTN4 LAMA5 LAMC3 AGRN ITGB5	7.94e-06	59	66	5	M27218
Pathway	KEGG_ECM_RECEPTOR_INTERACTION	VWF LAMA5 LAMC3 AGRN ITGB5	4.48e-05	84	66	5	M7098
Pubmed	Functional proteomics mapping of a human signaling pathway.	ZNF675 KANK1 ZBTB16 FBN2 VWF AP2A2 MYCBP2 LAMA5 ZNF83 SVEP1 NOTCH2	3.05e-07	591	88	11	15231748
Pubmed	Prediction of the coding sequences of mouse homologues of KIAA gene: IV. The complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.	ERGIC1 HBS1L ZNF836 RIMKLB ZNF473 AP2A2 ABLIM3 SLITRK1 NUP160	4.56e-06	493	88	9	15368895
Pubmed	The zinc finger-only protein Zfp260 is a novel cardiac regulator and a nuclear effector of alpha1-adrenergic signaling.	ZNF146 ZNF260	6.33e-06	2	88	2	16166646
Pubmed	The Role of Promyelocytic Leukemia Zinc Finger (PLZF) and Glial-Derived Neurotrophic Factor Family Receptor Alpha 1 (GFRα1) in the Cryopreservation of Spermatogonia Stem Cells.	ZBTB16 GFRA1	6.33e-06	2	88	2	36768269
Pubmed	Cloning, characterization, and chromosome assignment of Zfp146 the mouse ortholog of human ZNF146, a gene amplified and overexpressed in pancreatic cancer, and Zfp260 a closely related gene.	ZNF146 ZNF260	6.33e-06	2	88	2	10449921
Pubmed	Transportin-mediated nuclear import of heterogeneous nuclear RNP proteins.	TNPO1 TNPO2	6.33e-06	2	88	2	9298975
Pubmed	Transportin-1 and Transportin-2: protein nuclear import and beyond.	TNPO1 TNPO2	6.33e-06	2	88	2	24780099
Pubmed	Ischemia-induced Netrin-4 promotes neovascularization through endothelial progenitor cell activation via Unc-5 Netrin receptor B.	NTN4 UNC5B	6.33e-06	2	88	2	31914695
Pubmed	The connecting segment between both epidermal growth factor-like domains in blood coagulation factor IX contributes to stimulation by factor VIIIa and its isolated A2 domain.	EGF F9	6.33e-06	2	88	2	11925427
Pubmed	FBXO45-MYCBP2 regulates mitotic cell fate by targeting FBXW7 for degradation.	CUL1 MYCBP2 NOTCH2	6.97e-06	15	88	3	31285543
Pubmed	Comparative proteomic analysis of supportive and unsupportive extracellular matrix substrates for human embryonic stem cell maintenance.	FBN2 LAMA5 AGRN ITGB5	8.06e-06	50	88	4	23658023
Pubmed	The STUbL RNF4 regulates protein group SUMOylation by targeting the SUMO conjugation machinery.	TNPO1 ERGIC1 FBN2 ZNF146 ZNF473 AP2A2 GLI4 ZNF696 LTF ITGB5 NUP160 NOTCH2 ZNF260	1.03e-05	1203	88	13	29180619
Pubmed	GITR engagement preferentially enhances proliferation of functionally competent CD4+CD25+FoxP3+ regulatory T cells.	TNFRSF18 F9	1.90e-05	3	88	2	20139172
Pubmed	Gut microbiota regulate hepatic von Willebrand factor synthesis and arterial thrombus formation via Toll-like receptor-2.	VWF TLR2	1.90e-05	3	88	2	28572286
Pubmed	The IL33 receptor ST2 contributes to mechanical hypersensitivity in mice with neuropathic pain.	TLR2 IL1RL1	1.90e-05	3	88	2	33596932
Pubmed	Hepatic Expression of NTN4 and Its Receptors in Patients with Hepatocellular Carcinoma.	NTN4 UNC5B	1.90e-05	3	88	2	38156865
Pubmed	Application of a molecular diagnostic algorithm for haemophilia A and B using next-generation sequencing of entire F8, F9 and VWF genes.	VWF F9	1.90e-05	3	88	2	27734074
Pubmed	Netrin-4 inhibits angiogenesis via binding to neogenin and recruitment of Unc5B.	NTN4 UNC5B	1.90e-05	3	88	2	18719102
Pubmed	Cross talk between engulfment receptors stabilin-2 and integrin αvβ5 orchestrates engulfment of phosphatidylserine-exposed erythrocytes.	STAB2 ITGB5	1.90e-05	3	88	2	22566688
Pubmed	EGF/TGFβ1 co-stimulation of oral squamous cell carcinoma cells causes an epithelial-mesenchymal transition cell phenotype expressing laminin 332.	EGF LAMA5	1.90e-05	3	88	2	20819124
Pubmed	Salivary IL-33 and sST2 levels in relation to TLR2 rs111200466 polymorphism and periodontitis.	TLR2 IL1RL1	1.90e-05	3	88	2	37427857
Pubmed	The endothelial cell receptor stabilin-2 regulates VWF-FVIII complex half-life and immunogenicity.	STAB2 VWF	1.90e-05	3	88	2	30124466
Pubmed	Hemophilia A and B mice, but not VWF-/-mice, display bone defects in congenital development and remodeling after injury.	VWF F9	1.90e-05	3	88	2	31594977
Pubmed	The first EGF domain of coagulation factor IX attenuates cell adhesion and induces apoptosis.	EGF F9	1.90e-05	3	88	2	27129300
Pubmed	Intestinal microbes influence development of thymic lymphocytes in early life.	ZBTB16 TLR2	1.90e-05	3	88	2	31964813
Pubmed	ALS-associated fused in sarcoma (FUS) mutations disrupt Transportin-mediated nuclear import.	TNPO1 TNPO2	1.90e-05	3	88	2	20606625
Pubmed	In silico approach to inhibition of signaling pathways of Toll-like receptors 2 and 4 by ST2L.	TLR2 IL1RL1	1.90e-05	3	88	2	21897866
Pubmed	Family-based genome scan for age at onset of late-onset Alzheimer's disease in whole exome sequencing data.	NTN4 LAMC3	1.90e-05	3	88	2	26394601
Pubmed	Involvement of transportin 2-mediated HuR import in muscle cell differentiation.	TNPO1 TNPO2	1.90e-05	3	88	2	17475777
Pubmed	Immunomodulation via novel use of TLR4 by the filarial nematode phosphorylcholine-containing secreted product, ES-62.	TLR2 IL1RL1	3.79e-05	4	88	2	15611251
Pubmed	Heparin/heparan sulfate controls fibrillin-1, -2 and -3 self-interactions in microfibril assembly.	FBN2 FBN3	3.79e-05	4	88	2	25034023
Pubmed	Binding of netrin-4 to laminin short arms regulates basement membrane assembly.	NTN4 LAMC3	3.79e-05	4	88	2	17588941
Pubmed	The nucleoporin Nup98 is a site for GDP/GTP exchange on ran and termination of karyopherin beta 2-mediated nuclear import.	TNPO1 TNPO2	3.79e-05	4	88	2	10875935
Pubmed	Repressors NFI and NFY participate in organ-specific regulation of von Willebrand factor promoter activity in transgenic mice.	VWF NFIX	3.79e-05	4	88	2	20431063
Pubmed	Purification and identification of a novel subunit of protein serine/threonine phosphatase 4.	PPP4R1 PPP4R1L	3.79e-05	4	88	2	10026142
Pubmed	Histoplasma capsulatum cell wall {beta}-glucan induces lipid body formation through CD18, TLR2, and dectin-1 receptors: correlation with leukotriene B4 generation and role in HIV-1 infection.	TLR2 ALOX5	3.79e-05	4	88	2	19299700
Pubmed	Karyopherin beta 2B participates in mRNA export from the nucleus.	TNPO1 TNPO2	3.79e-05	4	88	2	12384575
Pubmed	Generation of a germ cell-specific mouse transgenic CHERRY reporter, Sohlh1-mCherryFlag.	ZBTB16 GFRA1	3.79e-05	4	88	2	22965810
Pubmed	Transportins 1 and 2 are redundant nuclear import factors for hnRNP A1 and HuR.	TNPO1 TNPO2	3.79e-05	4	88	2	15037768
Pubmed	A pilot study on prostate cancer risk and pro-inflammatory genotypes: pathophysiology and therapeutic implications.	TLR2 ALOX5	3.79e-05	4	88	2	20388081
Pubmed	Toll-like receptor 2 regulates intestinal inflammation by controlling integrity of the enteric nervous system.	TLR2 GFRA1	3.79e-05	4	88	2	23994200
Pubmed	An agrin minigene rescues dystrophic symptoms in a mouse model for congenital muscular dystrophy.	LAMA5 AGRN	3.79e-05	4	88	2	11565031
Pubmed	PTEN identified as important risk factor of chronic obstructive pulmonary disease.	SCUBE2 EGF TLR2 MTR LRP6 AKR1C4 ALOX5	4.73e-05	374	88	7	19625176
Pubmed	Genome-wide meta-analysis identifies new susceptibility loci for migraine.	ADRA1B KANK1 FBN2 GFRA1	4.73e-05	78	88	4	23793025
Pubmed	Transcriptome-based systematic identification of extracellular matrix proteins.	NTN4 LAMA5 LAMC3 AGRN	4.97e-05	79	88	4	18757743
Pubmed	Pathway-based evaluation of 380 candidate genes and lung cancer susceptibility suggests the importance of the cell cycle pathway.	SCUBE2 EGF TLR2 MTR LRP6 AKR1C4 ALOX5	5.31e-05	381	88	7	18676680
Pubmed	Polymorphisms in innate immunity genes and lung cancer risk in Xuanwei, China.	SCUBE2 EGF TLR2 MTR LRP6 AKR1C4 ALOX5	5.40e-05	382	88	7	19170196
Pubmed	Generation of functional multipotent adult stem cells from GPR125+ germline progenitors.	ZBTB16 ADAM2 GFRA1	6.05e-05	30	88	3	17882221
Pubmed	Src family tyrosine kinase Lyn mediates VWF/GPIb-IX-induced platelet activation via the cGMP signaling pathway.	VWF F9	6.30e-05	5	88	2	18550847
Pubmed	Genetic mapping of the absence of third molars in EL mice to chromosome 3.	EGF NOTCH2	6.30e-05	5	88	2	14514757
Pubmed	Capturing genes encoding membrane and secreted proteins important for mouse development.	LRP6 AGRN	6.30e-05	5	88	2	7604039
Pubmed	Regulation of melanoma cell migration and invasion by laminin-5 and alpha3beta1 integrin (VLA-3).	LAMA5 LAMC3	6.30e-05	5	88	2	11964076
Pubmed	Multiple functions of the integrin alpha6beta4 in epidermal homeostasis and tumorigenesis.	LAMA5 LAMC3	6.30e-05	5	88	2	16581764
Pubmed	Multiple genes encoding zinc finger domains are expressed in human T cells.	ZNF19 ZNF20 ZNF45	6.68e-05	31	88	3	2288909
Pubmed	Single cell RNA-sequencing identified Dec2 as a suppressive factor for spermatogonial differentiation by inhibiting Sohlh1 expression.	ZBTB16 GFRA1	9.43e-05	6	88	2	30988352
Pubmed	NOTCH2 Hajdu-Cheney Mutations Escape SCFFBW7-Dependent Proteolysis to Promote Osteoporosis.	CUL1 NOTCH2	9.43e-05	6	88	2	29149593
Pubmed	Laminin alpha1 globular domains 4-5 induce fetal development but are not vital for embryonic basement membrane assembly.	LAMA5 AGRN	9.43e-05	6	88	2	15668394
Pubmed	TAF4b is required for mouse spermatogonial stem cell development.	ZBTB16 GFRA1	9.43e-05	6	88	2	25727968
Pubmed	Extracellular matrix of secondary lymphoid organs impacts on B-cell fate and survival.	LAMA5 AGRN	9.43e-05	6	88	2	23847204
Pubmed	Genetic susceptibility to distinct bladder cancer subphenotypes.	SCUBE2 EGF TLR2 MTR LRP6 AKR1C4 ALOX5	9.90e-05	421	88	7	19692168
Pubmed	Sequential use of transcriptional profiling, expression quantitative trait mapping, and gene association implicates MMP20 in human kidney aging.	EGF MATN1 MTR LTF	1.15e-04	98	88	4	19834535
Pubmed	Global genetic analysis in mice unveils central role for cilia in congenital heart disease.	LAMA5 C2orf74 ZBTB14 DNAH11	1.25e-04	100	88	4	25807483
Pubmed	The heterogeneity of spermatogonia is revealed by their topology and expression of marker proteins including the germ cell-specific proteins Nanos2 and Nanos3.	ZBTB16 GFRA1	1.32e-04	7	88	2	19818747
Pubmed	Impact on venous thrombosis risk of newly discovered gene variants associated with FVIII and VWF plasma levels.	STAB2 VWF	1.32e-04	7	88	2	21029358
Pubmed	A 3D structural SARS-CoV-2-human interactome to explore genetic and drug perturbations.	AP2A2 USP54	1.32e-04	7	88	2	34845387
Pubmed	Fras1 deficiency results in cryptophthalmos, renal agenesis and blebbed phenotype in mice.	LAMA5 AGRN	1.75e-04	8	88	2	12766770
Pubmed	LRRK2 functions as a Wnt signaling scaffold, bridging cytosolic proteins and membrane-localized LRP6.	LRP6 LRRK1	2.25e-04	9	88	2	22899650
Pubmed	Microfibril-associated glycoprotein-2 interacts with fibrillin-1 and fibrillin-2 suggesting a role for MAGP-2 in elastic fiber assembly.	FBN2 VWF	2.25e-04	9	88	2	12122015
Pubmed	NANOS2 acts as an intrinsic regulator of gonocytes-to-spermatogonia transition in the murine testes.	ZBTB16 GFRA1	2.25e-04	9	88	2	29339164
Pubmed	F-box protein FBXL19-mediated ubiquitination and degradation of the receptor for IL-33 limits pulmonary inflammation.	CUL1 IL1RL1	2.25e-04	9	88	2	22660580
Pubmed	Mice lacking the extracellular matrix adaptor protein matrilin-2 develop without obvious abnormalities.	FBN2 MATN1	2.25e-04	9	88	2	15296947
Pubmed	Efficient suppression of FGF-2-induced ERK activation by the cooperative interaction among mammalian Sprouty isoforms.	EGF FRS2	2.25e-04	9	88	2	16339969
Pubmed	Biochemical Reduction of the Topology of the Diverse WDR76 Protein Interactome.	FBN2 TNPO2 LAMA5 AGRN HNRNPLL	2.42e-04	219	88	5	31353912
Pubmed	A human skeletal muscle interactome centered on proteins involved in muscular dystrophies: LGMD interactome.	ZBTB16 VWF MAN2A2 MYCBP2 ZSCAN23 ITGB5 NOTCH2	2.73e-04	497	88	7	23414517
Pubmed	Biochemical and genetic evidence for a role of IGHMBP2 in the translational machinery.	IGHMBP2 ZBTB14	2.81e-04	10	88	2	19299493
Pubmed	Trophoblast-specific expression and function of the integrin alpha 7 subunit in the peri-implantation mouse embryo.	LAMA5 LAMC3	2.81e-04	10	88	2	11784026
Pubmed	Basement membrane distortions impair lung lobation and capillary organization in the mouse model for fraser syndrome.	LAMA5 AGRN	2.81e-04	10	88	2	15623520
Pubmed	Tollip, a new component of the IL-1RI pathway, links IRAK to the IL-1 receptor.	TLR2 IL1RL1	2.81e-04	10	88	2	10854325
Pubmed	Fbxo45 inhibits calcium-sensitive proteolysis of N-cadherin and promotes neuronal differentiation.	CUL1 MYCBP2	3.43e-04	11	88	2	25143387
Pubmed	A forward genetic screen in mice identifies mutants with abnormal cortical patterning.	MYCBP2 LRP6	3.43e-04	11	88	2	23968836
Pubmed	Mutations in LAMB1 cause cobblestone brain malformation without muscular or ocular abnormalities.	LAMA5 LAMC3	3.43e-04	11	88	2	23472759
Pubmed	Novel role for Netrins in regulating epithelial behavior during lung branching morphogenesis.	NTN4 UNC5B	3.43e-04	11	88	2	15186747
Pubmed	Regional differences in the expression of laminin isoforms during mouse neural tube development.	LAMA5 LAMC3	3.43e-04	11	88	2	21524702
Pubmed	Foxl2 functions in sex determination and histogenesis throughout mouse ovary development.	ZBTB16 PLXNC1 AKR1C4	3.73e-04	55	88	3	19538736
Pubmed	Characterization of the Extracellular Matrix of Normal and Diseased Tissues Using Proteomics.	FBN2 VWF LAMA5 AGRN	3.93e-04	135	88	4	28675934
Pubmed	Polymorphisms in DNA repair genes modulate survival in cisplatin/gemcitabine-treated non-small-cell lung cancer patients.	EGF MTR	4.11e-04	12	88	2	16407418
Pubmed	Interleukin-33 Promotes Serotonin Release from Enterochromaffin Cells for Intestinal Homeostasis.	ZBTB16 IL1RL1	4.11e-04	12	88	2	33220232
Pubmed	IL-33 signaling contributes to the pathogenesis of myeloproliferative neoplasms.	TLR2 IL1RL1	4.11e-04	12	88	2	26011644
Pubmed	FLRT2 and FLRT3 act as repulsive guidance cues for Unc5-positive neurons.	NTN4 UNC5B	4.11e-04	12	88	2	21673655
Pubmed	Molecular dissection of laminin alpha 5 in vivo reveals separable domain-specific roles in embryonic development and kidney function.	LAMA5 AGRN	4.11e-04	12	88	2	16750824
Pubmed	Tuft-Cell-Derived Leukotrienes Drive Rapid Anti-helminth Immunity in the Small Intestine but Are Dispensable for Anti-protist Immunity.	IL1RL1 ALOX5	4.11e-04	12	88	2	32160525
Pubmed	Molecular patterning of the embryonic cranial mesenchyme revealed by genome-wide transcriptional profiling.	VWF UNC5B LAMC3	4.59e-04	59	88	3	31351040
Pubmed	LDL Receptor-Related Protein 6 Modulates Ret Proto-Oncogene Signaling in Renal Development and Cystic Dysplasia.	LRP6 GFRA1	4.85e-04	13	88	2	26047795
Pubmed	Gonocytes-to-spermatogonia transition initiates prior to birth in murine testes and it requires FGF signaling.	ZBTB16 GFRA1	4.85e-04	13	88	2	28341395
Pubmed	Mesangial cells organize the glomerular capillaries by adhering to the G domain of laminin alpha5 in the glomerular basement membrane.	LAMA5 AGRN	4.85e-04	13	88	2	12682087
Pubmed	Inhibition of notch1-dependent cardiomyogenesis leads to a dilated myopathy in the neonatal heart.	VWF NOTCH2	4.85e-04	13	88	2	20558824
Pubmed	Mammalian APE1 controls miRNA processing and its interactome is linked to cancer RNA metabolism.	PPP4R1 HBS1L RIMKLB EGF AP2A2 LAMC3 ABLIM3 HNRNPLL ZBTB14	5.60e-04	925	88	9	28986522
Pubmed	Platr4 is an early embryonic lncRNA that exerts its function downstream on cardiogenic mesodermal lineage commitment.	VWF LAMA5	5.65e-04	14	88	2	36347239
Pubmed	Mast cells as sensors of cell injury through IL-33 recognition.	TLR2 IL1RL1	5.65e-04	14	88	2	21239713
Pubmed	Basement membrane composition in the early mouse embryo day 7.	LAMA5 LAMC3	6.51e-04	15	88	2	15895400
Interaction	LYPD1 interactions	ZNF146 LRP6 ADGRF1 ITGB5 NOTCH2	5.11e-06	58	87	5	int:LYPD1
Interaction	FBXO2 interactions	CUL1 FBN2 PLXNC1 UNC5B LAMA5 LAMC3 ADGRF1 AGRN ITGB5 NOTCH2	1.10e-05	411	87	10	int:FBXO2
Interaction	IGFL3 interactions	FBN2 MYCBP2 LAMA5 AGRN NOTCH2	1.82e-05	75	87	5	int:IGFL3
Interaction	LTBP2 interactions	FBN2 GLI4 ZNF696 ZNF791 ZNF260	3.34e-05	85	87	5	int:LTBP2
Interaction	ADAM7 interactions	ADAM19 ZNF146 MYCBP2 ADAM2	3.52e-05	43	87	4	int:ADAM7
Interaction	PRG3 interactions	FBN2 LRP6 ITGB5 NOTCH2	5.92e-05	49	87	4	int:PRG3
Interaction	MFAP5 interactions	ERGIC1 FBN2 VWF LAMA5	7.49e-05	52	87	4	int:MFAP5
Interaction	ZNF791 interactions	GLI4 ZNF791 NOTCH2	8.40e-05	20	87	3	int:ZNF791
GeneFamily	Zinc fingers C2H2-type\|ZF class homeoboxes and pseudogenes	ZNF675 ZBTB49 ZNF19 ZNF20 ZNF836 ZBTB16 ZNF146 ZNF473 ZNF45 GLI4 ZNF696 ZNF83 ZSCAN23 ZNF791 ZNF583 ZBTB14 ZNF829 ZNF260	2.37e-11	718	63	18	28
GeneFamily	Laminin subunits	LAMA5 LAMC3	7.71e-04	12	63	2	626
GeneFamily	Armadillo repeat containing\|Importins	TNPO1 TNPO2	1.76e-03	18	63	2	596
GeneFamily	ADAM metallopeptidase domain containing\|CD molecules	ADAM19 ADAM2	3.97e-03	27	63	2	47
Coexpression	NABA_ECM_GLYCOPROTEINS	INTS6L NTN4 FBN2 VWF MATN1 LAMA5 LAMC3 AGRN FBN3 SVEP1 OTOG	5.98e-11	196	88	11	M3008
Coexpression	NABA_ECM_GLYCOPROTEINS	INTS6L NTN4 FBN2 VWF MATN1 LAMA5 LAMC3 AGRN SVEP1 OTOG	9.19e-10	191	88	10	MM17059
Coexpression	NABA_CORE_MATRISOME	INTS6L NTN4 FBN2 VWF MATN1 LAMA5 LAMC3 AGRN FBN3 SVEP1 OTOG	2.18e-09	275	88	11	M5884
Coexpression	NABA_MATRISOME	INTS6L NTN4 ADAM19 FBN2 VWF SCUBE2 EGF MUC17 PLXNC1 MATN1 LAMA5 LAMC3 ADAM2 MFRP AGRN F9 SVEP1 OTOG	5.54e-09	1008	88	18	MM17056
Coexpression	NABA_MATRISOME	INTS6L NTN4 ADAM19 FBN2 VWF SCUBE2 EGF MUC17 PLXNC1 MATN1 LAMA5 LAMC3 ADAM2 AGRN F9 FBN3 SVEP1 OTOG	7.29e-09	1026	88	18	M5889
Coexpression	NABA_CORE_MATRISOME	INTS6L NTN4 FBN2 VWF MATN1 LAMA5 LAMC3 AGRN SVEP1 OTOG	2.54e-08	270	88	10	MM17057
Coexpression	NABA_BASEMENT_MEMBRANES	NTN4 LAMA5 LAMC3 AGRN	9.88e-06	40	88	4	M5887
Coexpression	MEISSNER_BRAIN_HCP_WITH_H3K4ME3_AND_H3K27ME3	NTN4 ADRA1B KANK1 SCUBE2 MTUS1 UNC5B NFIX LAMC3 LRRK1 ABLIM3 ITGB5 GFRA1 SVEP1 DNAH11	1.31e-05	1074	88	14	M1941
Coexpression	GSE25087_FETAL_VS_ADULT_TREG_UP	MAN2A2 TLR2 TNFRSF18 AGRN NOTCH2 DNAH11	5.58e-05	198	88	6	M4641
Coexpression	GSE19198_CTRL_VS_IL21_TREATED_TCELL_6H_DN	CELF6 ZBTB16 AP2A2 TLR2 USP54 ABLIM3	5.58e-05	198	88	6	M7229
Coexpression	GSE43955_1H_VS_60H_ACT_CD4_TCELL_DN	TNPO1 ERGIC1 HBS1L C1R TNFRSF18 GFRA1	5.74e-05	199	88	6	M9651
Coexpression	LEE_BMP2_TARGETS_UP	NTN4 ZBTB16 VWF C1R LAMC3 AKR1C4 LRRK1 LTF AGRN ITGB5 VPS13B	7.97e-05	805	88	11	MM1067
ToppCell	Fetal_29-31_weeks-Epithelial-alveolar_epithelial_cell_type_2/Club-like_(AT2/Club-like)-D150\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	NTN4 ADRA1B KANK1 MTUS1 TLR2 USP54 FBN3	6.79e-08	179	88	7	815b959ce8721c5ded70c0ca6e318dafc691746e
ToppCell	PND10-Immune-Immune_Lymphocytic_T/NK-Lymphocytic_ILC-NK-ILC-ILC_prolif\|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	STAB2 ZBTB16 TNFRSF18 IL1RL1 RFC4 ALOX5	1.08e-06	169	88	6	20fbf78382fb0ba9a63ab1aa0abc615476994ac5
ToppCell	Fetal_29-31_weeks-Epithelial-alveolar_epithelial_cell_type_2/Club-like_(AT2/Club-like)\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	NTN4 KANK1 MTUS1 TLR2 USP54 FBN3	1.88e-06	186	88	6	2ea5ff14861e5f91d0e6a5767c403a24045d715c
ToppCell	renal_medulla_nuclei-Adult_normal_reference\|renal_medulla_nuclei / Celltypes from Cells and Nuclei per compartment and clinical group	KANK1 ZBTB16 EGF MTUS1 MTR ZNF83	2.13e-06	190	88	6	f1363f7806cfc4f14fbc1b0e8dac2de813a88eee
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-high_collagen-matrisome_fibroblast\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	ADRA1B UNC5B C1R LAMC3 GFRA1 SVEP1	2.26e-06	192	88	6	9093a9e94a25682d109a7f6edc256a25a61103a0
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-high_collagen-matrisome_fibroblast-\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	ADRA1B UNC5B C1R LAMC3 GFRA1 SVEP1	2.26e-06	192	88	6	9ed5d49621ec1aa01716dc369bba1450b5f015f5
ToppCell	5'-Adult-Appendix-Endothelial-blood_vessel_EC-Mature_venous_EC\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	NTN4 VWF MTUS1 LAMA5 IL1RL1 ABLIM3	2.33e-06	193	88	6	c0973a2c97deb7176c2f617c8760a55f7edc9839
ToppCell	10x5'v1-week_12-13-Endothelial-stroma\|week_12-13 / cell types per 3 fetal stages;per 3',per 5'	STAB2 VWF MTUS1 LAMA5 ABLIM3 AGRN	2.70e-06	198	88	6	122215d9288533ad03562cf777e846504863df9a
ToppCell	10x5'v1-week_12-13-Endothelial\|week_12-13 / cell types per 3 fetal stages;per 3',per 5'	STAB2 VWF MTUS1 LAMA5 ABLIM3 AGRN	2.70e-06	198	88	6	307dd09e6bc820a148f3000f18dae7aedba4be0b
ToppCell	368C-Endothelial_cells-Endothelial-E\|Endothelial_cells / Donor, Lineage, Cell class and subclass (all cells)	ZBTB16 PLXNC1 MATN1 SVEP1 WDR53	1.46e-05	156	88	5	4877aabf647238c0279e497345b6a6d5ee07ef9c
ToppCell	368C-Endothelial_cells-Endothelial-E-\|Endothelial_cells / Donor, Lineage, Cell class and subclass (all cells)	ZBTB16 PLXNC1 MATN1 SVEP1 WDR53	1.46e-05	156	88	5	1d681fa17e62815f5d5f90c86be3c248b38e011b
ToppCell	5'-GW_trimst-1.5-LargeIntestine-Mesenchymal-fibroblastic-Stromal_3_(KCNN3+)\|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	FBN2 SCUBE2 LAMC3 AGRN GFRA1	1.51e-05	157	88	5	beab0ac47202266b04543c02cfcdda012375e879
ToppCell	PND10-Immune-Immune_Lymphocytic_T/NK-Lymphocytic_ILC-NK-ILC\|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	STAB2 ZBTB16 TNFRSF18 IL1RL1 ALOX5	1.60e-05	159	88	5	5c7a099aa84ecc62bf9b5e1609e5b6b77889f175
ToppCell	kidney_cells-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-Collagen-low_Matrisome-low_fibroblast\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	C1R LAMC3 IL1RL1 GFRA1 SVEP1	2.34e-05	172	88	5	1ef243bce63d841c25e4b74d029d1377f84bcc3d
ToppCell	droplet-Liver-nan-3m-Myeloid-Kupffer_cell\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ETAA1 LRP6 LAMC3 LRRK1 HPS3	2.34e-05	172	88	5	1f335ccb92b22d0412954e8fc3af212f96410b67
ToppCell	kidney_cells-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-Collagen-low_Matrisome-low_fibroblast-\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	C1R LAMC3 IL1RL1 GFRA1 SVEP1	2.34e-05	172	88	5	ab1c81be29f93ca8920c6ab5ab92f497a9256d3f
ToppCell	droplet-Liver-nan-3m-Myeloid\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ETAA1 LRP6 LAMC3 LRRK1 HPS3	2.34e-05	172	88	5	bb96c896d125e10b71e94e2bdad243899045af5c
ToppCell	facs-Lung-EPCAM-3m-Lymphocytic-Alox5+_Lymphocyte\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	STAB2 ETAA1 TNFRSF18 IL1RL1 ALOX5	2.47e-05	174	88	5	a8bd1fa08bf061a627529a38e5a23a68b6d80697
ToppCell	facs-Lung-EPCAM-3m-Lymphocytic-lymphocyte\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	STAB2 ETAA1 TNFRSF18 IL1RL1 ALOX5	2.47e-05	174	88	5	7f8f6a15a823809effd37c1a5b09ef19b6d67755
ToppCell	facs-Lung-18m-Hematologic-Lymphocytic_NK_ILC-Alox5+_lymphocyte-Alox5+_lymphocyte\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	STAB2 IGHMBP2 TNFRSF18 IL1RL1 ALOX5	2.68e-05	177	88	5	b7cfa3776f58377e35830780650d236b5cceecee
ToppCell	facs-Lung-18m-Hematologic-Lymphocytic_NK_ILC-Alox5+_lymphocyte\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	STAB2 IGHMBP2 TNFRSF18 IL1RL1 ALOX5	2.68e-05	177	88	5	1730e640986e50943bd781b7d949bcc5b7c12dde
ToppCell	facs-Lung-EPCAM-18m-Lymphocytic-Alox5+_Lymphocyte\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	STAB2 IGHMBP2 TNFRSF18 IL1RL1 ALOX5	2.90e-05	180	88	5	b28363626f4d2a552abde3434cc1df2e2121aba5
ToppCell	facs-Lung-EPCAM-18m-Lymphocytic-lymphocyte\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	STAB2 IGHMBP2 TNFRSF18 IL1RL1 ALOX5	2.90e-05	180	88	5	67b062f2ef7e20f392e00c646f4985c415d40de9
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Immune-Lymphocytic_B-Plasma_Cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	ADAM19 PLXNC1 TNFRSF18 LRRK1 ALOX5	2.98e-05	181	88	5	6cdee2f56bc633b387b4dbbd78c624edbd712c24
ToppCell	Mid-temporal_gyrus_(MTG)-Neuronal-Inh_GABAergic-i_Gaba_2-GABA_VIP_2-Inh_L2-5_VIP_TOX2\|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	ADRA1B FBN2 MTUS1 LAMC3 FBN3	2.98e-05	181	88	5	35bcdcd2651149692e5b150e887c0f450c81d2d4
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Immune-Lymphocytic_B-Plasma_Cell-\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	ADAM19 PLXNC1 TNFRSF18 LRRK1 ALOX5	2.98e-05	181	88	5	b75b8b025257bccfe661fd0f92ab284b2a9c12ee
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Immune-Lymphocytic_B\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	ADAM19 PLXNC1 TNFRSF18 LRRK1 ALOX5	2.98e-05	181	88	5	5a4fe0eca7cbc9cbc8a2fdbe795a7c5f4052a659
ToppCell	COVID-19-Epithelial_cells-AT2\|COVID-19 / group, cell type (main and fine annotations)	NTN4 KANK1 EGF MTUS1 ADGRF1	3.22e-05	184	88	5	369b82f793deab672204558ae4e112cfa5aa9ccc
ToppCell	kidney_cells-Adult_normal_reference-Mesenchymal-Fibroblast-Collagen-low_Matrisome-low_fibroblast\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	ADRA1B ADAM19 C1R LAMC3 GFRA1	3.31e-05	185	88	5	e1fbec55b71f604189eb2431768fadbaa0453a83
ToppCell	kidney_cells-Adult_normal_reference-Mesenchymal-Fibroblast-Collagen-low_Matrisome-low_fibroblast-\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	ADRA1B ADAM19 C1R LAMC3 GFRA1	3.31e-05	185	88	5	9d933cd5ebc8368fd37aa83113d2dfa6938ff72d
ToppCell	Fetal_29-31_weeks-Epithelial-alveolar_epithelial_cell_type_1-D150\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	FBN2 LAMA5 USP54 AGRN FBN3	3.48e-05	187	88	5	4ae7465174e0295d2c3b614b321a3b2f514dd22a
ToppCell	COVID-19-Epithelial_cells\|COVID-19 / group, cell type (main and fine annotations)	NTN4 KANK1 MTUS1 USP54 DNAH11	3.57e-05	188	88	5	c9cdee6f8d42ee69f5fb335f25084603c511bd29
ToppCell	kidney_cells-Renal_AKI_(acute_kidney_injury)-Endothelial-lymphatic_endothelial_cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	ADAM19 STAB2 VWF MTUS1 UNC5B	3.57e-05	188	88	5	26915db8863f4115b46a81982e187322e21600fd
ToppCell	kidney_cells-Renal_AKI_(acute_kidney_injury)-Endothelial-lymphatic_endothelial_cell-lymphatic_endothelial_cell_of_renal_cortex\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	ADAM19 STAB2 VWF MTUS1 UNC5B	3.57e-05	188	88	5	3f76c0f912f8f023ea425be7f43593b3d7f967e3
ToppCell	5'-Adult-LargeIntestine-Mesenchymal-fibroblastic-Stromal_2_(NPY+)\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	FBN2 SCUBE2 LAMA5 C1R LAMC3	3.57e-05	188	88	5	997dcfc4f08738ab398d8abc15e4fd2fc6619862
ToppCell	Control-Epithelial_cells\|Control / group, cell type (main and fine annotations)	PPP4R1 NTN4 KANK1 MTUS1 USP54	3.57e-05	188	88	5	707ebf76cc6fb600b2f07793cf4ea9482c0de79d
ToppCell	kidney_cells-Renal_AKI_(acute_kidney_injury)-Endothelial-lymphatic_endothelial_cell-lymphatic_endothelial_cell_of_renal_cortex-lymphatic_endothelial_cell_of_renal_cortex\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	ADAM19 STAB2 VWF MTUS1 UNC5B	3.57e-05	188	88	5	61ee7b152745164293d8a44ef91ee2393efbdca5
ToppCell	AT2_cells-Cryobiopsy_01\|World / lung cells shred on cell class, cell subclass, sample id	SCUBE2 NFIX C1R ADGRF1 AGRN	3.66e-05	189	88	5	2d32f09efa982ae458568f6b1cd06bb5078d42a3
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-Collagen-low_Matrisome-low_fibroblast\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	ADRA1B C1R LAMC3 GFRA1 SVEP1	3.76e-05	190	88	5	2306aa9dbeaef3be8484a5b236605de23cd75d4c
ToppCell	droplet-Heart-4Chambers-18m-Endothelial-endocardial_endothelial_cells\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	KANK1 VWF PLXNC1 ADAM2 ZNF791	3.76e-05	190	88	5	6f71a9f74af7cd9a674753cfc9833ebe5bba0fa2
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-Collagen-low_Matrisome-low_fibroblast-\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	ADRA1B C1R LAMC3 GFRA1 SVEP1	3.76e-05	190	88	5	1f83f7f24288a3b9ab33c2e113e845dba96adc8a
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	ADRA1B C1R LAMC3 GFRA1 SVEP1	3.85e-05	191	88	5	a58c75e9580139fb370b498d95660f10f3a2a27b
ToppCell	Fetal_29-31_weeks-Epithelial-alveolar_epithelial_cell_type_2-D150\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	NTN4 KANK1 MTUS1 TLR2 USP54	3.85e-05	191	88	5	34cc997e4e5c727495f321e6807a84aa124da486
ToppCell	COVID-19-lung-AT2\|lung / Disease (COVID-19 only), tissue and cell type	NTN4 KANK1 MTUS1 USP54 ADGRF1	3.85e-05	191	88	5	276455a64c2c3503d5048615762eb2ee37f0ac70
ToppCell	Epithelial-alveolar_epithelial_cell_type_1/2_(AT1/AT2-like)\|World / Lineage, Cell type, age group and donor	KANK1 MTUS1 LAMA5 USP54 FBN3	3.85e-05	191	88	5	d3733c8c4bda70c4390e5601fdda6188a64be944
ToppCell	Children_(3_yrs)-Epithelial\|Children_(3_yrs) / Lineage, Cell type, age group and donor	NTN4 KANK1 MTUS1 LRP6 USP54	3.85e-05	191	88	5	e432c6e1ae82dddf84314ce73d2b7a991630d905
ToppCell	5'-Adult-Distal_Rectal-Endothelial-blood_vessel_EC-Mature_venous_EC\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	NTN4 VWF MTUS1 LAMA5 IL1RL1	3.95e-05	192	88	5	eafead22bba48ac5ee568faa8946c444445c1034
ToppCell	Adult-Epithelial\|Adult / Lineage, Cell type, age group and donor	NTN4 KANK1 MTUS1 LRP6 USP54	3.95e-05	192	88	5	efb962a5fd3b9bdfd8cf8d13c435e29c8271713e
ToppCell	Children_(3_yrs)-Immune-monocyte-D046\|Children_(3_yrs) / Lineage, Cell type, age group and donor	FBN2 PLXNC1 TLR2 LRRK1 NOTCH2	4.05e-05	193	88	5	58e1930a1d80ad3729ab9604ac8ebf7308232a3d
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Mesenchymal\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	ADRA1B C1R LAMC3 GFRA1 SVEP1	4.05e-05	193	88	5	f1199518c3626fd29bfce65070dd21a660671213
ToppCell	renal_papilla_nuclei-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell-Inner_Medullary_Collecting_Duct_Cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	NTN4 SCUBE2 ABLIM3 ADGRF1 ALOX5	4.05e-05	193	88	5	a5695ce2e24a62026ae28f3dea07ca4a435206b8
ToppCell	Fetal_29-31_weeks-Epithelial\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	NTN4 KANK1 MTUS1 USP54 FBN3	4.05e-05	193	88	5	a0ca3231992f14abcf1a6129573bace320e89d2a
ToppCell	Bronchial-NucSeq-Epithelial-Epi_airway_secretory-Secretory_Club\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	ADRA1B SCUBE2 MTUS1 TLR2 ZSCAN23	4.36e-05	196	88	5	ed76eeb37400ca154feae9b7ebaddb6c434f8b81
ToppCell	AT2_cells-IPF_03\|World / lung cells shred on cell class, cell subclass, sample id	MTUS1 NFIX C1R ADGRF1 AGRN	4.46e-05	197	88	5	5e0d222872a25bb9e9069d3dffda2844bb69874a
ToppCell	kidney_cells-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	C1R LAMC3 IL1RL1 GFRA1 SVEP1	4.46e-05	197	88	5	4cf4e9553397cd8dee883dbec24f41bec41aff99
ToppCell	5'-Adult-Distal_Rectal-Endothelial-blood_vessel_EC\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	VWF MTUS1 LAMA5 IL1RL1 ABLIM3	4.57e-05	198	88	5	d1f54ed3ef5e05ebda7da999e172d168dc6802cd
ToppCell	5'-Adult-Distal_Rectal-Endothelial\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	VWF MTUS1 LAMA5 IL1RL1 ABLIM3	4.57e-05	198	88	5	8d6b0b9da7c1e64155cbcbb04ad38d129a29030c
ToppCell	COVID-19-kidney-Fibroblast-2\|kidney / Disease (COVID-19 only), tissue and cell type	C1R LAMC3 LRRK1 GFRA1 SVEP1	4.57e-05	198	88	5	ca26ca460856b1faaa3e83766da6abdf63af2b51
ToppCell	Bronchial-NucSeq-Epithelial\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	NTN4 KANK1 MTUS1 LRP6 USP54	4.68e-05	199	88	5	5f7da3eab58ace6cddb3179a415cd839d5767958
ToppCell	Tracheal-NucSeq-Immune_Lymphocytic-B-B_plasma-B_plasma_IgA\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	ADAM19 PLXNC1 TNFRSF18 LRRK1 ALOX5	4.68e-05	199	88	5	1bb02f41f3cc76a28581e38b0ca4c36b930b85b4
ToppCell	Tracheal-NucSeq-Immune_Lymphocytic-B-B_plasma\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	ADAM19 PLXNC1 TNFRSF18 LRRK1 ALOX5	4.68e-05	199	88	5	2f60682f1b82918a65e8851e99c9e3398845b62f
ToppCell	5'-Parenchyma_lung-Epithelial-Alveolar_epithelium-type_II_pneumocyte-AT2-AT2_L.0.1.3.1\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	NTN4 KANK1 MTUS1 LRP6 USP54	4.68e-05	199	88	5	2dc33804f6691d7c9682e6c9b885e945fb97fc36
ToppCell	Tracheal-NucSeq-Immune_Lymphocytic-B\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	ADAM19 PLXNC1 TNFRSF18 LRRK1 ALOX5	4.68e-05	199	88	5	58242d78517c05fa367a7c6edac57ef79107453c
ToppCell	Neuronal-Inhibitory-iA-iA_3(VIP)-VIP_2-TYR-L2-5\|Neuronal / cells hierarchy compared to all cells using T-Statistic	KANK1 FBN2 MTUS1 LAMC3 FBN3	4.79e-05	200	88	5	04954fbe1e2264077228bb582c9a5897a70e6da2
ToppCell	Neuronal-Inhibitory-iA-iA_3(VIP)-VIP_3\|Neuronal / cells hierarchy compared to all cells using T-Statistic	KANK1 MTUS1 LAMC3 FBN3 SVEP1	4.79e-05	200	88	5	7e51715525fdb001b7042b2bfcb9de81ecb5e4ee
ToppCell	5'-Adult-SmallIntestine-Endothelial-blood_vessel_EC\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	NTN4 VWF MTUS1 LAMA5 IL1RL1	4.79e-05	200	88	5	cd3c638961144a2fc91c437a173cc37c7452fa74
ToppCell	Neuronal-Inhibitory-iA-iA_3(VIP)-VIP_2-TYR\|Neuronal / cells hierarchy compared to all cells using T-Statistic	KANK1 FBN2 MTUS1 LAMC3 FBN3	4.79e-05	200	88	5	bfdafb024a7b20d46837b2e6480dd4929253cd62
ToppCell	frontal_cortex-Non-neuronal-oligodendrocyte-Oligo-Oligo_Rassf10\|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	KANK1 MATN1 ADGRF1 ALOX5	9.14e-05	119	88	4	ec3af1253f03b3ec403f73243237acf08ad56789
ToppCell	Cerebellum-Macroglia-POLYDENDROCYTE-P1-P1_1\|Cerebellum / BrainAtlas - Mouse McCarroll V32	FBN2 MATN1 ALOX5 GFRA1	1.04e-04	123	88	4	e0eb95f1da12687230b47f0a7367b6138bc7ff1a
ToppCell	Cerebellum-Macroglia-POLYDENDROCYTE-P1\|Cerebellum / BrainAtlas - Mouse McCarroll V32	FBN2 MATN1 ALOX5 GFRA1	1.04e-04	123	88	4	356e2b1b47fdfc2bb2fcd45e44b452fe811f0fd8
ToppCell	Cerebellum-Macroglia-POLYDENDROCYTE-P1-P1_1-Polydendrocyte.Tnr.Tnr_(Tnr)-\|Cerebellum / BrainAtlas - Mouse McCarroll V32	FBN2 MATN1 ALOX5 GFRA1	1.04e-04	123	88	4	b06a38d1081b4485b519853d8c9a2cddfb1e9e75
ToppCell	Cerebellum-Macroglia-POLYDENDROCYTE-P1-P1_1-Polydendrocyte.Tnr.Tnr_(Tnr)\|Cerebellum / BrainAtlas - Mouse McCarroll V32	FBN2 MATN1 ALOX5 GFRA1	1.04e-04	123	88	4	f60c1dd89da0e204f73772fe0c319eeca82e7e8a
ToppCell	Cerebellum-Macroglia-POLYDENDROCYTE\|Cerebellum / BrainAtlas - Mouse McCarroll V32	FBN2 MATN1 ALOX5 GFRA1	1.04e-04	123	88	4	15f951b4eb2f39888e51e1af18c329953d253f7f
ToppCell	frontal_cortex-Neuronal-GABAergic_neuron-Vip-Vip_Col15a1_Pde1a\|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	CELF6 ADRA1B ZBTB16 UNC5B	1.29e-04	130	88	4	56b9c3325e011f1dbaf9efc71bd6e1af4f96fda6
ToppCell	BALF-PFMC-Severe-critical_progression_d12-22_no-steroids-Myeloid-Granulocytic-Neutrophil-Neu_c2-CXCR4(low)\|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)	CUL1 ADAM19 IGHMBP2 HPS3	1.36e-04	132	88	4	a1fda8c5287168c4f159203ed27cadfb4ce1b131
ToppCell	frontal_cortex-Neuronal-GABAergic_neuron-Vip-Vip_Crispld2_Htr2c\|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	ADRA1B ZBTB16 UNC5B LAMA5	2.01e-04	146	88	4	47368f981180ca6a8c81a50f7f9430f12456f609
ToppCell	facs-Trachea-18m-Mesenchymal-myofibroblast-tracheobronchial_smooth_muscle_cell-smooth_muscle_cell_of_trachea_l1\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	ADRA1B ZNF473 RFC4 ADGRF1	2.65e-04	157	88	4	1f21d78a467fe22c5ab75d0917b840c1ac93f32c
ToppCell	facs-Trachea-3m-Mesenchymal-myofibroblast-tracheobronchial_smooth_muscle_cell-smooth_muscle_cell_of_trachea_l1-41\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	FBN2 MTUS1 FRS2 HPS3	2.71e-04	158	88	4	6d2709b387945c015faa223c20d22b52a4082140
ToppCell	PND07-Immune-Immune_Lymphocytic_T/NK-Lymphocytic_ILC-NK-ILC-ILC_prolif\|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	FANCG STAB2 TNFRSF18 IL1RL1	2.78e-04	159	88	4	f7bccfeffa737f151417bf52ea45111b0957bce9
ToppCell	Children_(3_yrs)-Epithelial-alveolar_epithelial_cell_type_1/2_(AT1/AT2-like)-D139\|Children_(3_yrs) / Lineage, Cell type, age group and donor	ADRA1B KANK1 MTUS1 LAMA5	2.78e-04	159	88	4	8680b054622f573a82b1625fb93c2d5db81d1034
ToppCell	Fetal_29-31_weeks-Epithelial-club_cell-D062\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	ZNF19 ADRA1B MTUS1 FBN3	2.98e-04	162	88	4	5c9bc3c3857a99d8a3caf359a7eb279ce9cc1c81
ToppCell	PND10-Immune-Immune_Lymphocytic_T/NK-Lymphocytic_ILC-NK-ILC-ILC_mature\|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	STAB2 TNFRSF18 IL1RL1 ALOX5	3.06e-04	163	88	4	476e94e1d132eaaecb9e376bd32748a75ad22081
ToppCell	Fetal_brain-fetalBrain_Zhong_nature-GW16-Neuronal-GABAergic_neurons\|GW16 / Sample Type, Dataset, Time_group, and Cell type.	NTN4 ZBTB16 MYCBP2 SLITRK1	3.13e-04	164	88	4	4d7b2d0980fb4f47721fa2891151e2bd892ccb91
ToppCell	renal_medulla_nuclei-CKD+DKD_normotensive-Endothelial-lymphatic_endothelial_cell-lymphatic_endothelial_cell_of_renal_medulla-lymphatic_endothelial_cell_of_renal_medulla\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	RIMKLB STAB2 UNC5B ABLIM3	3.13e-04	164	88	4	a784f47f67a5eda84d58ad7d9400e3978edbb487
ToppCell	renal_medulla_nuclei-CKD+DKD_normotensive-Endothelial-lymphatic_endothelial_cell\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	RIMKLB STAB2 UNC5B ABLIM3	3.13e-04	164	88	4	1a1795969673232191425dde84ab24ee6a98143f
ToppCell	facs-Lung-EPCAM-3m-Endothelial-vein_endothelial_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ZNF146 VWF LAMC3 AGRN	3.13e-04	164	88	4	1d0d88132baaa3154c3e6e4ef0aff795afab08a2
ToppCell	PBMC_fresh-frozen-Severe-critical_convalescent_d14-21-Lymphocytic-Lymphocytic_T-CD8-positive,_alpha-beta_T_cell-T_CD8_c02-GPR183\|Severe-critical_convalescent_d14-21 / Compartment, severity and other cell annotations on 10x 3' data (130k)	ADAM19 TNFRSF18 IL1RL1 HNRNPLL	3.13e-04	164	88	4	e86899aa68aac572009618c7e017e6734b86357c
ToppCell	facs-Lung-EPCAM-3m-Endothelial-Vein_endothelial_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ZNF146 VWF LAMC3 AGRN	3.13e-04	164	88	4	bd2e10b015d5e6a338675500ec5d81dc39583b3e
ToppCell	renal_medulla_nuclei-CKD+DKD_normotensive-Endothelial-lymphatic_endothelial_cell-lymphatic_endothelial_cell_of_renal_medulla\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	RIMKLB STAB2 UNC5B ABLIM3	3.13e-04	164	88	4	8f074940afdbda88a4b697a7ddc687e09a4b818b
ToppCell	E18.5-samps-Mesenchymal-Matrix_fibroblast-MatrixFB-A\|E18.5-samps / Age Group, Lineage, Cell class and subclass	ADRA1B SCUBE2 ABLIM3 SVEP1	3.13e-04	164	88	4	519ab4fe885dfe4c50846f346a062acc2cb44299
ToppCell	facs-Brain_Non-Myeloid-Cerebellum-3m-Epithelial-neuronal_stem_cell\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ZBTB49 ADRA1B MATN1 DNAH11	3.20e-04	165	88	4	1703d3eb644b3c743ad3c5532b1d29ea010c79c8
ToppCell	PND14-Immune-Immune_Lymphocytic_T/NK-Lymphocytic_ILC-NK\|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	STAB2 TNFRSF18 IL1RL1 ALOX5	3.20e-04	165	88	4	004d793bf5bb6fb3b7bf38baf11b32d46375fe4d
ToppCell	renal_papilla_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell-Outer_Medullary_Collecting_Duct_Intercalated_Cell_Type_A\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	MTR ADAM2 ADGRF1 FBN3	3.27e-04	166	88	4	6fe8db8d45177a78605681f22e04fa8d0594f2df
ToppCell	PND03-Immune-Immune_Lymphocytic_T/NK-Lymphocytic_ILC-NK-ILC-ILC_prolif\|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	STAB2 TNFRSF18 IL1RL1 RFC4	3.35e-04	167	88	4	53e32d6687a07f486141df9f4ab998af4c03a507
ToppCell	10x5'-Lung-Lymphocytic_T_CD4/8-lo-Trm_Tgd\|Lung / Manually curated celltypes from each tissue	ZNF146 TNFRSF18 RFC4 ZNF829	3.35e-04	167	88	4	dcbcc658082910838c8082d71a64917055086cc4
ToppCell	PND10-Immune-Immune_Lymphocytic_T/NK-Lymphocytic_ILC-NK\|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	STAB2 TNFRSF18 IL1RL1 ALOX5	3.35e-04	167	88	4	84551ee71f9d8d03d514711fc7ca4422c810140b
ToppCell	frontal_cortex-Non-neuronal-leptomeningeal_cell-VLMC-VLMC_Osr1_Mc5r\|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	LAMC3 LRRK1 SVEP1 NOTCH2	3.43e-04	168	88	4	9930bd63b60c03f0152838a79eef77da1c2dd8e5
ToppCell	Control\|World / group, cell type (main and fine annotations)	NTN4 KANK1 ZBTB16 USP54	3.43e-04	168	88	4	a3511faf2cd2c2b9c8363c8b99da3f3609c43ed6
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast-kidney_interstitial_fibroblast_5\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	ADRA1B LAMC3 GFRA1 SVEP1	3.43e-04	168	88	4	d19a115365c5415e51c039718d7669de788fcf33
ToppCell	5'-Adult-LargeIntestine-Mesenchymal-fibroblastic-Stromal_1_(ADAMDEC1+)\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	ZBTB16 FBN2 C1R SVEP1	3.50e-04	169	88	4	c0824a93674e2bff0f09b2d2fab5bab016a2e379
Disease	intellectual developmental disorder with hypotonia, impaired speech, and dysmorphic facies (implicated_via_orthology)	TNPO1 TNPO2	8.20e-06	2	85	2	DOID:0081262 (implicated_via_orthology)
Disease	connective tissue disease (implicated_via_orthology)	FBN2 FBN3	2.46e-05	3	85	2	DOID:65 (implicated_via_orthology)
Disease	tongue squamous cell carcinoma (is_marker_for)	FANCG MTUS1 IL1RL1	1.67e-04	37	85	3	DOID:0050865 (is_marker_for)
Disease	C-C motif chemokine 28 measurement	HBS1L ZBTB16	5.31e-04	12	85	2	EFO_0020199
Disease	histidine measurement	TNPO1 NTN4 HPS3	9.26e-04	66	85	3	EFO_0009769
Disease	factor VIII measurement, Ischemic stroke	STAB2 VWF	1.36e-03	19	85	2	EFO_0004630, HP_0002140
Disease	cortical surface area measurement	ZNF675 NTN4 ZBTB16 FBN2 MYCBP2 NFIX LAMC3 ITGB5 FBN3 SVEP1 DNAH11	1.64e-03	1345	85	11	EFO_0010736
Disease	alcoholic liver disease	ZBTB16 FBN2 MTR	1.73e-03	82	85	3	EFO_0008573
Disease	forced expiratory volume	ADAM19 ZBTB16 SCUBE2 IGHMBP2 FRS2 IL1RL1 ABLIM3 SVEP1	1.98e-03	789	85	8	EFO_0004314
Disease	Neoplasm Invasiveness	ZBTB16 EGF ALOX5 NOTCH2	2.00e-03	184	85	4	C0027626
Disease	Reperfusion Injury	EGF TLR2 ALOX5	2.19e-03	89	85	3	C0035126
Disease	platelet measurement	HBS1L VWF EGF ITGB5 SVEP1	2.19e-03	315	85	5	EFO_0005036
Disease	anogenital venereal wart (is_marker_for)	TLR2 TNFRSF18	2.55e-03	26	85	2	DOID:11168 (is_marker_for)
Disease	cerebral amyloid deposition measurement	SLITRK1 ZBTB14 ZNF260	2.64e-03	95	85	3	EFO_0007707
Disease	Nephrotic Syndrome	KANK1 LAMA5	2.75e-03	27	85	2	C0027726
Disease	factor VIII measurement, von Willebrand factor measurement	STAB2 VWF	2.75e-03	27	85	2	EFO_0004629, EFO_0004630

Protein segments in the cluster

Peptide	Gene	Start	Entry
DAGLAKSIGVSNFNC	AKR1C4	156	P17516
VCGCGLAQSGFFFKN	ABLIM3	51	O94929
DGSFRVFGKAQCNDI	ADGRF1	246	Q5T601
FEKVNVAGDTFGNCG	ADAM19	541	Q9H013
IATCRFKAGSNCAEG	ADAM2	416	Q99965
VQCAFGATCAVKNGQ	AGRN	471	O00468
CEAFFNCNGLEAAFK	DNAH11	556	Q96DT5
CEAAADVANGQPGFK	ADRA1B	496	P35368
VNTEGSFQCVCNAGF	FBN3	506	Q75N90
KQDACQGDSGGVFAV	C1R	646	P00736
CAFVKFGSQGEAQAA	CELF6	176	Q96J87
GSEDNFARFVCKNNG	AP2A2	701	O94973
NAFVGGAKNCSLSVD	INTS6L	736	Q5JSJ4
AKAALNGADIYAGCC	HNRNPLL	221	Q8WVV9
CVSDVFKDQGSGFCI	HBS1L	491	Q9Y450
ETNCSAKFSGCGGNL	MFRP	291	Q9BY79
QNDATCLDKIGGFTC	NOTCH2	466	Q04721
KEFVQFVCSDGSGQA	NFIX	401	Q14938
EGFTLNSDGKTCNVC	MATN1	251	P21941
FVSDIGNQCACSSGK	MTUS1	256	Q9ULD2
ELCCGKQTAFFSSQG	LRRK1	1531	Q38SD2
KDVCIQFDGGNCSSV	PLXNC1	731	O60486
NGAGCRFEGQFSINK	ERGIC1	111	Q969X5
FGFEGKNCELDVTCN	F9	121	P00740
FGCGDVNAKASQAGQ	KANK1	1221	Q14678
GFGNVCANTDAEKIF	KCNH4	441	Q9UQ05
SQFQCASGQCIDGAL	LRP6	1291	O75581
KEQGAAFNCEQGCKS	FANCG	491	O15287
QACASCKDGFFGLDQ	LAMA5	806	O15230
DNFSCARNKGVLCSG	ITGB5	551	P18084
AFNAIFDGSTQKCSG	ETAA1	281	Q9NY74
CKQGAVVQHFFCDSG	OR6S1	171	Q8NH40
EIGKNANLTCSACFG	IL1RL1	226	Q01638
ANLTCSACFGKGTQF	IL1RL1	231	Q01638
TCLKNAIQAFGNGSD	GFRA1	336	P56159
EDATCQCLKGFAGDG	EGF	851	P01133
NNDAGFVAALDKACG	CUL1	386	Q13616
QTGQGIFAFKCARAE	FRS2	81	Q8WU20
CTDANGGVDCAAAKV	C2orf74	46	A8MZ97
FACGACGKAFGQSSQ	GLI4	351	P10075
FDCGLEAKNLGFNCT	MAN2A2	1081	P49641
ICNAGFELTTDGKNC	FBN2	601	P35556
NTIGSFKCRCNSGFA	FBN2	1091	P35556
NGGCDHFCKNIVGSF	SCUBE2	331	Q9NQ36
KVCAANFGDICHAVG	PPP4R1L	181	Q9P1A2
AAACPAGQVFVNCSD	OTOG	881	Q6ZRI0
GCNECGKAFSQFSTL	ZNF146	241	Q15072
FGDGCQNTASRCKNG	MUC17	4136	Q685J3
GVFAACQSGSFDKLE	RFC4	276	P35249
KVCAANFGDICSVVG	PPP4R1	231	Q8TF05
LCAGTGENKCAFSSQ	LTF	191	P02788
AAGCKVEAFAVAGQE	HPS3	36	Q969F9
ICECGLFDKANATGG	ALOX5	416	P09917
FIVKGSCFCNGHADQ	NTN4	256	Q9HB63
ICAGFAASGEKDFCQ	OVCH1	746	Q7RTY7
SNFAVIEAGLKCCQG	MTR	451	Q99707
VQAFNKGASCSAQGF	MYCBP2	2691	O75592
NGATCKDGANSFRCL	SVEP1	1356	Q4LDE5
KDGANSFRCLCAAGF	SVEP1	1361	Q4LDE5
GEGQKALECFCQAAS	NUP160	921	Q12769
QIACQACGKTFSDEG	ZBTB14	276	O43829
GVNADECKECGNAFS	ZNF20	251	P17024
LCEGKEGSQCAENFS	ZNF791	71	Q3KP31
GCNECGKAFSQFSTL	ZNF260	361	Q3ZCT1
AGAKAFVCDQCGAQF	ZBTB16	456	Q05516
CSECGKAFNGNSSLI	ZNF19	191	P17023
NKTCGLCGNFNIFAE	VWF	156	P04275
SLCFAAGNVTGDVCK	SLITRK1	11	Q96PX8
VKADNTCGFAKCTAG	IGHMBP2	891	P38935
CETFVFSGCNGNLNN	SPINT4	66	Q6UDR6
NTCEGAFGALQKICE	TNPO2	141	O14787
CADCGKAFGQRSDAA	ZNF696	211	Q9H7X3
DGTASCKCAAGFQGN	STAB2	1451	Q8WWQ8
TVVDFCKQDNGGCAK	STAB2	2081	Q8WWQ8
GSFCVCEANANVGFI	RIMKLB	271	Q9ULI2
CEANANVGFIAFDKA	RIMKLB	276	Q9ULI2
ASCGNIFSCGAEDGK	WDR53	206	Q7Z5U6
GGAFCEGQAFQKTAC	UNC5B	281	Q8IZJ1
NTCEGAFGALQKICE	TNPO1	151	Q92973
ECNECGKAFNKGSNL	ZNF829	381	Q3KNS6
CGNDNFQLKGCKSVD	ZNF675	106	Q8TD23
QSQGKFSFGFQCIDC	TNFRSF18	101	Q9Y5U5
EACFFICGDNLSTKG	VPS13B	476	Q7Z7G8
CDICGRGFSNFSNLK	ZBTB49	481	Q6ZSB9
KTLEAGGNNFICSCE	TLR2	526	O60603
CEECGKGFSQASNLL	ZNF45	446	Q02386
CIECGKAFSNGSFLA	ZNF583	326	Q96ND8
CNEFGGAFIQSSKLA	ZNF836	696	Q6ZNA1
CNECGKVFGLNSSLA	ZNF83	431	P51522
FECDQCGKAFGQSTR	ZNF473	591	Q8WTR7
GDSCIFCALKGIFNQ	USP54	71	Q70EL1
QCSVCGKAFSQNAGL	ZSCAN23	306	Q3MJ62
AVSDFSVGGRCKCNG	LAMC3	261	Q9Y6N6