Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyBiologicalProcessdevelopmental pigmentation

GRK3 ADAMTS9 HPS5 ANKRD27

3.35e-0558654GO:0048066
DomainFerI

FER1L5 FER1L6

1.30e-045682SM01202
DomainFerB

FER1L5 FER1L6

1.30e-045682SM01201
DomainFerlin_B-domain

FER1L5 FER1L6

1.30e-045682IPR012561
DomainFerlin_C

FER1L5 FER1L6

1.30e-045682PF16165
DomainFerlin_C

FER1L5 FER1L6

1.30e-045682IPR032362
DomainFerIin_dom

FER1L5 FER1L6

1.30e-045682IPR012968
DomainFerI

FER1L5 FER1L6

1.30e-045682PF08151
DomainFerB

FER1L5 FER1L6

1.30e-045682PF08150
DomainC2

FER1L5 MCTP2 FER1L6 PLCE1

1.33e-03131684PF00168
DomainC2

FER1L5 MCTP2 FER1L6 PLCE1

1.57e-03137684SM00239
DomainC2

FER1L5 MCTP2 FER1L6 PLCE1

1.79e-03142684PS50004
Domain-

FER1L5 MCTP2 FER1L6 PLCE1

2.08e-031486842.60.40.150
Domain-

CAPN14 SMOC2 KCNIP3 STAT2 PLCE1

2.61e-032616851.10.238.10
DomainC2_dom

FER1L5 MCTP2 FER1L6 PLCE1

3.02e-03164684IPR000008
DomainEF-hand-dom_pair

CAPN14 SMOC2 KCNIP3 STAT2 PLCE1

3.92e-03287685IPR011992
DomainRASGEF

PLCE1 SOS2

4.01e-0326682PS00720
Pubmed

Thrombosis Related ABO, F5, MTHFR, and FGG Gene Polymorphisms in Morbidly Obese Patients.

FGG F5

1.16e-05369227999448
Pubmed

Testis-enriched ferlin, FER1L5, is required for Ca2+-activated acrosome reaction and male fertility.

FER1L5 FER1L6

1.16e-05369236696506
Pubmed

Fibrinogen alpha and gamma genes and factor VLeiden in children with thromboembolism: results from 2 family-based association studies.

FGG F5

1.16e-05369219515723
Pubmed

Reduced thrombin generation increases host susceptibility to group A streptococcal infection.

FGG F5

1.16e-05369219056689
Pubmed

Fibrinogen γ' increases the sensitivity to activated protein C in normal and factor V Leiden plasma.

FGG F5

1.16e-05369224951429
Pubmed

Genetic variation in coagulation and fibrinolytic proteins and their relation with acute myocardial infarction: a systematic review.

FGG F5

2.32e-05469211748101
Pubmed

GWAS for discovery and replication of genetic loci associated with sudden cardiac arrest in patients with coronary artery disease.

MCTP2 CHRNB4 PLCE1

3.91e-053369321658281
Pubmed

Prothrombotic phenotype of protein Z deficiency.

FGG F5

5.79e-05669210829076
Pubmed

GWAS identifies four novel eosinophilic esophagitis loci.

CAPN14 ANKRD27

5.79e-05669225407941
Pubmed

Genetics of venous thrombosis: insights from a new genome wide association study.

FGG F5

8.09e-05769221980494
Pubmed

A genome-wide association study for venous thromboembolism: the extended cohorts for heart and aging research in genomic epidemiology (CHARGE) consortium.

FGG F5

1.08e-04869223650146
Pubmed

The Nab2 and Stat6 genes share a common transcription termination region.

IL1R1 STAT2

1.73e-04106929126479
Pubmed

Genetic variation associated with preterm birth: a HuGE review.

IL1R1 F5

2.11e-041169216301860
Pubmed

Gene variants associated with venous thrombosis: confirmation in the MEGA study.

FGG F5

2.53e-041269220128871
Pubmed

Prothrombotic genetic variants and atherosclerosis in patients with cerebral ischemia of arterial origin.

FGG F5

2.98e-041369218848323
Pubmed

Distribution of the mammalian Stat gene family in mouse chromosomes.

IL1R1 STAT2

2.98e-04136928530075
Pubmed

Sequential Activation of Two Pathogen-Sensing Pathways Required for Type I Interferon Expression and Resistance to an Acute DNA Virus Infection.

ZBP1 IL1R1

3.48e-041469226682986
Pubmed

Genetic predictors of fibrin D-dimer levels in healthy adults.

FGG F5

4.57e-041669221502573
Pubmed

Genome-wide meta-analysis identifies regions on 7p21 (AHR) and 15q24 (CYP1A2) as determinants of habitual caffeine consumption.

PITRM1 PROX2

5.18e-041769221490707
Pubmed

Sequential arrival and graded secretion of Sema3F by olfactory neuron axons specify map topography at the bulb.

OR10AD1 OR6P1

5.81e-041869220550939
Pubmed

Genome-wide CRISPR screen identifies HNRNPL as a prostate cancer dependency regulating RNA splicing.

EVA1C GRK3 SYNJ2 NAIP CPD SMOC2 KCNIP3 HPS5 MCTP2 SOS2

6.83e-041489691028611215
Pubmed

Interaction of amyotrophic lateral sclerosis/frontotemporal lobar degeneration-associated fused-in-sarcoma with proteins involved in metabolic and protein degradation pathways.

RTRAF TIMM50 LRRIQ4 PLCE1

6.98e-0420169425192599
Pubmed

Genome-wide association analysis of eosinophilic esophagitis provides insight into the tissue specificity of this allergic disease.

CAPN14 CCDC81

7.95e-042169225017104
Pubmed

An orthogonal proteomic-genomic screen identifies AIM2 as a cytoplasmic DNA sensor for the inflammasome.

ZBP1 GBP3

7.95e-042169219158679
Pubmed

Genome-wide Identification of Foxf2 Target Genes in Palate Development.

ADAMTS9 SMOC2

9.55e-042369232040930
Pubmed

Cis-Repression of Foxq1 Expression Affects Foxf2-Mediated Gene Expression in Palate Development.

ADAMTS9 SMOC2

9.55e-042369233898467
Pubmed

IRF8 Regulates Transcription of Naips for NLRC4 Inflammasome Activation.

NAIP IL1R1

9.55e-042369229576451
Pubmed

Biochemical and phosphoproteomic analysis of the helix-loop-helix protein E47.

RTRAF TIMM50 CPD

1.82e-0312169322354994
Pubmed

Identifications of novel host cell factors that interact with the receptor-binding domain of the SARS-CoV-2 spike protein.

CDC40 ELP1 HPS5 ANKRD27 FAM111B PLCE1

1.84e-0365069638777146
CytobandEnsembl 112 genes in cytogenetic band chr2q11

RFX8 KCNIP3 IL1R1 FER1L5

8.66e-05153694chr2q11
GeneFamilyFerlin family

FER1L5 FER1L6

9.86e-056472828
GeneFamilyOlfactory receptors, family 6

OR6B3 OR6B2 OR6P1

3.14e-0451473153
ToppCellE18.5-samps-Endothelial-Mature_fetal_endothelial-endothelial_cells_B|E18.5-samps / Age Group, Lineage, Cell class and subclass

STAB2 CD38 GBP3 SLFN5 RFX8

5.47e-06163695d6f9b7280c44d120df5a72dfc2ebb26ffbb5752b
ToppCellFrontal_cortex-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)-Pvalb-Inhibitory_Neuron.Gad1Gad2.Pvalb-Unc5b_(MGE-derived_cortical_interneurons--Chandelier_cells)-|Frontal_cortex / BrainAtlas - Mouse McCarroll V32

CPSF4L FER1L5 MCTP2 CHRNB4

8.49e-0683694e7f7ad1cd8b08172ef2432a80554aa8174a6c675
ToppCellFrontal_cortex-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)-Pvalb-Inhibitory_Neuron.Gad1Gad2.Pvalb-Unc5b_(MGE-derived_cortical_interneurons--Chandelier_cells)|Frontal_cortex / BrainAtlas - Mouse McCarroll V32

CPSF4L FER1L5 MCTP2 CHRNB4

8.49e-068369433fa6e4a01be4d9945b273c884066d4bfdeaa62d
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Epithelial-Renal_corpuscle_epithelial_cell-glomerular_visceral_epithelial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

OLAH SYNJ2 ADAMTS9 F5 PLCE1

9.59e-06183695612d93df03252d4d2ccdce5a9bc162cfd9172a1a
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Epithelial-Renal_corpuscle_epithelial_cell-glomerular_visceral_epithelial_cell-Podocyte|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

OLAH SYNJ2 ADAMTS9 F5 PLCE1

9.59e-06183695eb559ae3ae252d9365c24ef557dd49b78ed6d898
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Renal_corpuscle_epithelial_cell-parietal_epithelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

EVA1C SYNJ2 FGG F5 PLCE1

1.09e-05188695b21e93a70583c30d05c0833cd3d4d4bca44a039e
ToppCellT_cells-ISG-high_CD4+_T_cells|World / Immune cells in Kidney/Urine in Lupus Nephritis

ZBP1 GBP3 SLFN5 RFX8 STAT2

1.09e-051886956f8946d4710f6e32c937213f99b790b098b8819c
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Renal_corpuscle_epithelial_cell-parietal_epithelial_cell-Parietal_Epithelial_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

EVA1C SYNJ2 FGG F5 PLCE1

1.09e-05188695874404a4fd9aa42873f6c53dc42da22d3b0fdb9e
ToppCellIPF-Endothelial-Lymphatic|Endothelial / Disease state, Lineage and Cell class

STAB2 CD38 OSBP2 MCTP2 PLCE1

1.30e-05195695de88e9d22044b4b3e29676ad02b3e9299cc920ad
ToppCellCV-Mild-1|CV / Virus stimulation, Condition and Cluster

ZBP1 CD38 GBP3 SLFN5 STAT2

1.40e-051986954b078714c49e7befb7b113d72485e712236d35fa
ToppCellBAL-Severe-cDC_1|Severe / Compartment, Disease Groups and Clusters

ZBP1 NAIP SLFN5 STX11 STAT2

1.44e-051996959f5750212b887f92761ade33fc6e108cd5275297
ToppCellEndothelial-Endothelial-F|Endothelial / shred on cell class and cell subclass (v4)

ZBP1 GBP3 SLFN5 STAT2

3.88e-051226942cb8bb63c69aed4d4504b9d97219b8707666f950
ToppCelldroplet-Heart-HEART_(ALL_4:4:4:1:1)-30m-Endothelial|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ZBP1 CPSF4L GBP3 RFX8

4.40e-051266944eeea015efe17e0aae5bd76b71fa70b5149dfada
ToppCellGlobus_pallidus-Neuronal-Excitatory-eN3(Slc17a7_Gad1Gad2)-Sphkap-Excitatory_Neuron.Gad1Gad2.Sphkap-Cpne4_(Basomedial_amygdaloid_nucleus_(BMA))|Globus_pallidus / BrainAtlas - Mouse McCarroll V32

PRSS22 SCN10A FER1L5

8.10e-05546937670a6eb185ae0d8c3c0cb17f8eaa9970355187b
ToppCellGlobus_pallidus-Neuronal-Excitatory-eN3(Slc17a7_Gad1Gad2)-Sphkap-Excitatory_Neuron.Gad1Gad2.Sphkap-Cpne4_(Basomedial_amygdaloid_nucleus_(BMA))-|Globus_pallidus / BrainAtlas - Mouse McCarroll V32

PRSS22 SCN10A FER1L5

8.10e-055469379f804e73f859c0e8192d9e9e6ee2282f7f1691b
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Renal_corpuscle_epithelial_cell-parietal_epithelial_cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

STAB2 LRRC53 DDX53 PLCE1

8.45e-05149694cc6224c6b79f43b97adc1ce48ca4906bff2ad318
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Renal_corpuscle_epithelial_cell-parietal_epithelial_cell-Parietal_Epithelial_Cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

STAB2 LRRC53 DDX53 PLCE1

8.45e-0514969424a7538b54b2a5291503c7493fefed4e45e8d710
ToppCellMS-CD4-antiviral_CD4|MS / Condition, Cell_class and T cell subcluster

ZBP1 SLFN5 RFX8 F5

9.13e-05152694b1eba2d5a6da3eeb83d40a92976e3e8751ed18ee
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Epithelial-Renal_corpuscle_epithelial_cell-glomerular_visceral_epithelial_cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

ADAMTS9 STX11 F5 PLCE1

9.84e-05155694e7f49e2fdaf184fa6b4e685518004e7deff1316d
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Epithelial-Renal_corpuscle_epithelial_cell-glomerular_visceral_epithelial_cell-Podocyte|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

ADAMTS9 STX11 F5 PLCE1

9.84e-051556945a872ca70ae8c30b57f45a6772d7bf565e0c2663
ToppCellfacs-Trachea-3m-Endothelial-endothelial_cell_of_trachea-tracheal_endothelial_cell-tracheal_endothelial_cell_l7|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

CD38 SCN10A LRRIQ4 SLFN5

1.06e-0415869478b48b110b777bcc4c07cd23388bee911c0231d6
ToppCelldroplet-Lung-30m-Hematologic-myeloid-classical_monocyte-classical_monocyte_l2|30m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

ZBP1 GBP3 SLFN5 STX11

1.22e-04164694f88871d3b9307112eb7ced4c629f5704326ecae8
ToppCellPosterior_cortex-Neuronal-Excitatory-eN2(Slc17a7_Slc17a6)-Syt6-Excitatory_Neuron.Slc17a7.Syt6-Nnat_(Neuron.Slc17a7.Syt6-Nnat)|Posterior_cortex / BrainAtlas - Mouse McCarroll V32

SCN10A CCDC81 RFX8

1.22e-0462693dd2e222d454fb78fed8b37901cbf04c0080ed010
ToppCellPosterior_cortex-Neuronal-Excitatory-eN2(Slc17a7_Slc17a6)-Syt6-Excitatory_Neuron.Slc17a7.Syt6-Nnat_(Neuron.Slc17a7.Syt6-Nnat)-|Posterior_cortex / BrainAtlas - Mouse McCarroll V32

SCN10A CCDC81 RFX8

1.22e-04626936a3f990e8d59392ad909634a239b3ab4f13d8855
ToppCelldroplet-Lung-18m-Hematologic-myeloid-myeloid_dendritic_cell|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

GRK3 ST3GAL5 PRSS22 KCNIP3

1.34e-04168694d6078e3a79d315d6090906e171a7d67a9206b2c7
ToppCell5'-GW_trimst-2-LargeIntestine-Hematopoietic-T_cells-NK_cell|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

ZBP1 CD38 SLFN5 MCTP2

1.44e-04171694f16cb64b8844c2668922c786888efaa9f873afcc
ToppCellMid-temporal_gyrus_(MTG)-Neuronal-Inh_GABAergic-i_Gaba_2-GABA_VIP_2-Inh_L2-6_VIP_VIP|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

COL21A1 SMOC2 MCTP2 PLCE1

1.57e-04175694e78bf0c33a741bb97e987e41ac33da9e623a08ec
ToppCellCF-Myeloid-Neutrophil|Myeloid / Disease state, Lineage and Cell class

ZBP1 CPD IL1R1 MCTP2

1.57e-041756948020c3a34f77e68e8149f87481fb1dddd2ac675e
ToppCellmetastatic_Lymph_Node-Myeloid_cells-Activated_DCs|metastatic_Lymph_Node / Location, Cell class and cell subclass

OLAH GRK3 ST3GAL5 CCDC81

1.64e-04177694370aee11a6dc2c6f4366a13c3171f37bc5b32d65
ToppCellPND10-Epithelial-Epithelial_Airway-Neurosecretory-PNEC|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

SMOC2 KCNIP3 MCTP2 F5

1.82e-041826941923932a9c60e9ec33db69ded441210d1fb07bec
ToppCellPND10-Epithelial-Epithelial_Airway-Neurosecretory-PNEC-PNEC_mature|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

SMOC2 KCNIP3 MCTP2 F5

1.82e-0418269469ff652f74cc47fbe0bd665ab17c445c5b959dad
ToppCellAdult-Mesenchymal-pericyte_cell-D122|Adult / Lineage, Cell type, age group and donor

ADAMTS9 RFX8 KCNIP3 PLCE1

1.86e-04183694fc31a43a637423cb3bb9aa184a3a889a0b9aaea6
ToppCellSmart-seq2-tissue-resident_(Smart-seq2)-myeloid-myeloid_granulocytic-neutrophil|tissue-resident_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

NAIP CPD FGG F5

1.90e-041846947ecdf2645e9378cf2f5ce4557f2cf100e6f184ba
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Renal_corpuscle_epithelial_cell-parietal_epithelial_cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

EVA1C MCTP2 F5 PLCE1

1.94e-0418569434fcfd635c828dad9643bbf1c908d79282d6f5d9
ToppCellLPS_only|World / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

EVA1C ADAMTS9 CD38 GBP3

1.94e-04185694a72ccb147ca505880e2da8f6a70b9d570464a691
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Renal_corpuscle_epithelial_cell-parietal_epithelial_cell-Parietal_Epithelial_Cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

EVA1C MCTP2 F5 PLCE1

1.94e-041856948816f2909ed11833ff3d0ed96b9cb6d6fe9e1578
ToppCelltumor_Lymph_Node_/_Brain-Fibroblasts-Undetermined|Fibroblasts / Location, Cell class and cell subclass

RMI1 SYNJ2 ETFDH GBP3

1.98e-04186694403ac98f72a42721f84fbd7826f251a88ae534a2
ToppCellcritical-Myeloid-Monocyte-derived_Macrophage|Myeloid / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls

ST3GAL5 CD38 GBP3 STAT2

2.02e-0418769472e4aec49ea0c5fe6cee2a1a46369dbc90cd3fad
ToppCell5'-Airway_Nasal-Epithelial-Epithelial_transtional-secretory-club_cell-Club_(nasal)-Club_(nasal)_L.0.2.3.1|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

PITRM1 GBP3 OSBP2 RFX8

2.02e-04187694a6a112689d1c9049f57935ad9d2f4955538427de
ToppCellFetal_29-31_weeks-Immune-natural_killer_cell-D150|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

ZBP1 CD38 SLFN5 MCTP2

2.06e-041886941082861eb9e00409caa06d8b2a7b8e7f5fac94c9
ToppCellPCW_10-12-Epithelial-Epithelial_airway-epi_proximal_progenitor1_(6)|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung

ST3GAL5 VPS13A PRSS22 SMOC2

2.06e-04188694beb2df2332a46cc81b10e8e29fc9829020111f03
ToppCellLPS-IL1RA-Endothelial-Endothelial-Artery|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

EVA1C SYNJ2 COL21A1 F5

2.15e-04190694aed65d584ca0c25f6a8313c66b421a6618af82ea
ToppCellPCW_10-12-Mesenchymal-Mesenchymal_fibroblastic-mes_adventitial_fibro_(10)|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung

EVA1C FNDC5 GBP3 PLCE1

2.15e-041906944f775ee24b14733f06ae40b45f2dc1a0f0df0705
ToppCell10x_3'_v3-tissue-resident_(10x_3'_v3)-myeloid-myeloid_granulocytic-neutrophil|tissue-resident_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

OLAH CPD MCTP2 F5

2.19e-04191694b9b091d6b352d5128bb864ff52d2e5fb3387b766
ToppCellCalu_3-infected-SARSCoV2|infected / Cell line, Condition and Strain

ZBP1 GBP3 SLFN5 STAT2

2.19e-041916942da876d26f37a00dbdf1ee79d724306e8b20f304
ToppCellPCW_05-06-Mesenchymal-Mesenchymal_fibroblastic-mes_adventitial_fibro_(10)|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung

EVA1C COL21A1 FNDC5 SMOC2

2.19e-04191694156b467187331ac6ca390d6ca861d9670bb7b956
ToppCell10x_3'_v2v3-Non-neoplastic-Myeloid-Mono-Mono_naive-E|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

GRK3 NAIP CPD F5

2.19e-0419169463d4226a8b59f648bdc9f41e4b2d750dfa342034
ToppCellnormal_Pleural_Fluid-T/NK_cells-NK|normal_Pleural_Fluid / Location, Cell class and cell subclass

ZBP1 CD38 SLFN5 MCTP2

2.24e-0419269459dd4f5ae9f1cca78adf60b71661092ef09e6641
ToppCellSmart-start-Cell-Wel_seq-Neoplastic-Stem-like-OPC-like-OPC-like-F|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

ZNF630 STAB2 PROX2 MCTP2

2.28e-04193694315840bc48899f3a36d57b19197509de19716e3d
ToppCellPCW_07-8.5-Mesenchymal-Mesenchymal_fibroblastic-mes_adventitial_fibro_(10)|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

EVA1C FNDC5 SMOC2 PLCE1

2.28e-04193694cd45118ced91b10baed3b1068d4673ec99824b86
ToppCellPCW_13-14-Mesenchymal-Mesenchymal_fibroblastic-mes_adventitial_fibro_(10)|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung

EVA1C FNDC5 SMOC2 PLCE1

2.28e-04193694adc9fc94f9ec686a417d08c0b8b7b7ab687afec0
ToppCellPSB-critical-LOC-Epithelial-FOXN4+|LOC / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

RMI1 CCDC15 FAM111B PLCE1

2.28e-04193694b7d9c5bed524423e92f01496a9f8fad11b33a3f7
ToppCellmoderate-Myeloid-Monocyte-derived_Macrophage|Myeloid / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls

ST3GAL5 CD38 SLFN5 STAT2

2.28e-0419369422455801194bd8c73c5c397f5eac4f723429c383
ToppCell10x5'v1-week_17-19-Endothelial|week_17-19 / cell types per 3 fetal stages;per 3',per 5'

EVA1C STAB2 ADAMTS9 IL1R1

2.33e-04194694e141beafc9252e5d8c949252bfab53e127c881dc
ToppCell10x5'v1-week_17-19-Endothelial-stroma|week_17-19 / cell types per 3 fetal stages;per 3',per 5'

EVA1C STAB2 ADAMTS9 IL1R1

2.33e-04194694953578102ffc7b612ee8fce45e414750800fef5d
ToppCellASK452-Endothelial-Lymphatic|Endothelial / Donor, Lineage and Cell class of Lung cells from Dropseq

STAB2 TIMM50 OSBP2 PLCE1

2.37e-0419569420f492299a684ac1b7dd1bbc36a533cd6f9a1c93
ToppCellNasal_Brush|World / Tissue, Lineage and Cell class of Lung Cells from 10X

PRSS22 GBP3 SLFN5 FER1L6

2.37e-041956947509b980b6b293df02bec619ef5b83a6c7b49c03
ToppCellSmart-seq2-spleen_(Smart-seq2)-myeloid-myeloid_granulocytic-neutrophil|spleen_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

OLAH SCN10A CPD F5

2.37e-04195694d3755929ebbbf5e3afde44281e9056ddb614a291
ToppCellSmart-seq2-spleen_(Smart-seq2)-myeloid-myeloid_granulocytic|spleen_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

OLAH SCN10A CPD F5

2.37e-0419569419853c654ac64b3ae3bc99841c6cb29c8aaba85c
ToppCell3'-Airway_Nasal-Epithelial-Epithelial_transtional-secretory-club_cell-Club_(nasal)-Club_(nasal)_L.0.2.3.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

PRSS22 GBP3 SLFN5 FER1L6

2.37e-041956943f8ed20ad17afe1545e574e5ca5fe33c3704c7f3
ToppCellCV-Moderate-1|Moderate / Virus stimulation, Condition and Cluster

ZBP1 CD38 SLFN5 STAT2

2.42e-04196694b50cfcd87c5b67806450cb8b3c6860ab97f6d3b1
ToppCellMild-CD8+_T_activated|World / Disease group and Cell class

ZBP1 CD38 SLFN5 STAT2

2.42e-0419669479632190e44fcef9d7c11d9b9e37f2ebf0e6e255
ToppCellCOVID-19_Mild-Classical_Monocyte-cMono_3|COVID-19_Mild / Disease condition and Cell class

GRK3 NAIP MCTP2 F5

2.42e-04196694f245e929a286cb097130572e1027b4f01be8b04d
ToppCell5'-Adult-Appendix|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

STAB2 ADAMTS9 SMOC2 IL1R1

2.42e-04196694a579211ef14f348d0c5a290553150222dfbf1515
ToppCellCV-Moderate-1|CV / Virus stimulation, Condition and Cluster

ZBP1 CD38 SLFN5 STAT2

2.47e-04197694e3d00d850b4d191f9592ef993c0eaadfe5710b5f
ToppCell10x3'2.3-week_17-19-Endothelial-stroma-sinusoidal_EC|week_17-19 / cell types per 3 fetal stages;per 3',per 5'

EVA1C STAB2 ADAMTS9 IL1R1

2.47e-041976944e58bbf3ecb30b4c8199adcc04d2eb134d90de56
ToppCellCOVID-19_Severe-NK_activated|World / disease group, cell group and cell class

ZBP1 CD38 SLFN5 MCTP2

2.47e-04197694a60db36d1a192998e3ded63e0c7c08d41689f95f
ToppCellsevere_COVID-19-NK|severe_COVID-19 / disease group, cell group and cell class (v2)

ZBP1 CD38 SLFN5 MCTP2

2.52e-041986947f51e37516f717e424190e6584f1c74d357e2da4
ToppCellmild_COVID-19_(asymptomatic)-NK|World / disease group, cell group and cell class (v2)

ZBP1 CD38 SLFN5 MCTP2

2.52e-041986947a0aac52d785037455e068e1b25de4b2bf0fff79
ToppCellPBMC-Severe-Lymphocyte-T/NK-NK_cell-NK_activated|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

ZBP1 CD38 SLFN5 MCTP2

2.52e-041986940e918e9db9b884f5328d438e90efe065e27266ee
ToppCellMild-CD8+_T_activated|Mild / Disease group and Cell class

ZBP1 CD38 SLFN5 STAT2

2.52e-04198694ceac1b51bacfd0dd7fe7c6a666f7927055e1f380
ToppCellPBMC-Severe-Lymphocyte-T/NK-NK_cell-NK_activated-|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

ZBP1 CD38 SLFN5 MCTP2

2.52e-04198694ce92d5fbc2eac27fb246b044fb1914ab92506275
ToppCellPBMC-Severe-Lymphocyte-T/NK-NK_cell-NK_activated|Severe / Location, Disease Group, Cell group, Cell class (2021.03.09)

ZBP1 CD38 SLFN5 MCTP2

2.52e-04198694fed823d6e684d113bcc9ff3cd1803bb001aa02fa
ToppCellsevere_COVID-19-NK|World / disease group, cell group and cell class (v2)

ZBP1 CD38 SLFN5 MCTP2

2.52e-0419869436b1370ef68c4bbe0268933a6ef5e6022d992bdf
ToppCellPBMC-Severe-Lymphocyte-T/NK-NK_cell-NK_activated-|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

ZBP1 CD38 SLFN5 MCTP2

2.52e-041986941ef3a6bd681c223eed58300348adfef89df5563c
ToppCellBAL-Severe|BAL / Compartment, Disease Groups and Clusters

CD38 NAIP SLFN5 STAT2

2.52e-04198694f63cfcc57f46094ea0673bbc70ea443ebaca6176
ToppCell10x3'2.3-week_14-16-Endothelial|week_14-16 / cell types per 3 fetal stages;per 3',per 5'

EVA1C STAB2 ADAMTS9 COL21A1

2.56e-0419969441f046646fff65b7e51b63d3204f76ef32054781
ToppCellVE-CD4-antiviral_CD4|VE / Condition, Cell_class and T cell subcluster

ZBP1 LINS1 SLFN5 STAT2

2.56e-04199694056a0538ca5e825ae6195b4c76c208708a014533
ToppCell(03)_KRT6B+-(2)_GFP_FOXI1|(03)_KRT6B+ / shred by cell type by condition

RALBP1 GBP3 SLFN5 HPS5

2.56e-04199694c425e7975f492ed5cfcca022248adb627e1d27d4
ToppCell10x3'2.3-week_17-19-Myeloid_monocytic-monocyte-CD14_monocyte|week_17-19 / cell types per 3 fetal stages;per 3',per 5'

NAIP CPD STX11 F5

2.56e-0419969450a30d5ee99e51743a0dd60144fc341ff68da9af
ToppCellCOVID-19-lung|COVID-19 / Disease (COVID-19 only), tissue and cell type

GRK3 ST3GAL5 MCTP2 STAT2

2.56e-04199694155b03b859157013e9142e9248551369127d9204
ToppCell10x3'2.3-week_14-16-Endothelial-stroma|week_14-16 / cell types per 3 fetal stages;per 3',per 5'

EVA1C STAB2 ADAMTS9 COL21A1

2.56e-04199694ef7f7f7c861827574b120f48cf4052c563929081
ToppCell10x_3'_v3-blood_(10x_3'_v3)-myeloid-myeloid_granulocytic-neutrophil|blood_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

OLAH CPD MCTP2 SOS2

2.61e-042006946beabd5bad042d4d65c89c2f537c7376230f7c08
ToppCellmild-NK|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

ZBP1 CD38 SLFN5 MCTP2

2.61e-04200694a11fb1d7e124c352eb73fea0e0ec0fed577c97f7
ToppCellCOVID-19-COVID-19_Severe-Lymphocyte-T/NK-NK_activated|COVID-19_Severe / Disease, condition lineage and cell class

ZBP1 CD38 SLFN5 MCTP2

2.61e-042006946a77f9643646bafc1157bf1fc1e4c614860ee642
ToppCellCOVID-19_Severe-NK_activated|COVID-19_Severe / Disease condition and Cell class

ZBP1 CD38 SLFN5 MCTP2

2.61e-04200694f1f6c7f7f75f891c9ccf6bf58f4d65b9cf10bbd8
ToppCell10x_3'_v3-blood_(10x_3'_v3)-myeloid-myeloid_granulocytic|blood_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

OLAH CPD MCTP2 SOS2

2.61e-04200694026495aa7f1e7528a01d9199475cfc393677fc60
Diseaseeosinophilic esophagitis (is_implicated_in)

CAPN14 ANKRD27

5.21e-055682DOID:13922 (is_implicated_in)
Diseasefactor VIII measurement, venous thromboembolism

STAB2 FGG F5

6.66e-0534683EFO_0004286, EFO_0004630
Diseaselimb-girdle muscular dystrophy (implicated_via_orthology)

FER1L5 FER1L6

1.09e-047682DOID:11724 (implicated_via_orthology)
Diseasevenous thromboembolism, von Willebrand factor measurement

STAB2 FGG F5

1.26e-0442683EFO_0004286, EFO_0004629
Diseasepulse pressure measurement

EVA1C FBXO38 LCORL COL21A1 OR10AD1 ETFDH SCN10A SMOC2 FER1L5 PLCE1 SOS2

3.19e-0413926811EFO_0005763
DiseaseIschemic stroke, venous thromboembolism, stroke, Abnormal thrombosis, deep vein thrombosis, pulmonary embolism

FGG F5

6.96e-0417682EFO_0000712, EFO_0003827, EFO_0003907, EFO_0004286, HP_0001977, HP_0002140
Diseaseprothrombin time measurement

FGG F5

1.07e-0321682EFO_0008390
Diseasevenous thromboembolism, plasminogen activator inhibitor 1 measurement

FGG F5

1.07e-0321682EFO_0004286, EFO_0004792
Diseasevenous thromboembolism, tissue plasminogen activator measurement

FGG F5

1.28e-0323682EFO_0004286, EFO_0004791
Diseasepartial thromboplastin time

FGG F5

1.40e-0324682EFO_0004310
DiseaseD dimer measurement

FGG F5

2.18e-0330682EFO_0004507
Diseasefactor XI measurement, venous thromboembolism

FGG F5

2.18e-0330682EFO_0004286, EFO_0004694
Diseasevenous thromboembolism, factor VII measurement

FGG F5

3.49e-0338682EFO_0004286, EFO_0004619
Diseasetype 1 diabetes mellitus (implicated_via_orthology)

CD38 IL1R1

3.67e-0339682DOID:9744 (implicated_via_orthology)

Protein segments in the cluster

PeptideGeneStartEntry
EVKYFPFDQQNCTLK

CHRNB4

156

P30926
QDQIFPNLDKFLCLK

NAIP

1091

Q13075
IKLLDCDQELYKNFP

GRK3

496

P35626
KCQFAQKIREFKLLP

CPSF4L

161

A6NMK7
PQFYFAKAKRLDLCQ

CAPN14

81

A8MX76
KNIYRPDKFLQCVKN

CD38

276

P28907
QEFQRLLKELPECNY

RALBP1

301

Q15311
EDLLKNPFYLALQKC

ANKRD27

6

Q96NW4
CNPIIYSFRNKEIKE

OR10AD1

286

Q8NGE0
DAICRLQKKNLFPYN

LINS1

721

Q8NG48
QPNCYVLKNKDLEQA

MCTP2

601

Q6DN12
YLKRNQFEVFPQELC

LRRIQ4

171

A6NIV6
QKIVQKNRSKYDDPC

LRRC53

541

A6NM62
LNALFRKKDLPQNCD

LCORL

136

Q8N3X6
QQYSPEILACQFLKK

HPS5

766

Q9UPZ3
YKCLRNFLQEKDFCP

LNX2

71

Q8N448
CFKDNLNKPYLFSVL

PRSS22

91

Q9GZN4
SQKDKNFNLPRLCIR

GBP3

211

Q9H0R5
EYFPECLNLIKDKNL

ELP1

956

O95163
NHKTNDRCQLKFLPY

OSBP2

706

Q969R2
LANNPCEREKRNIYK

MTMR4

511

Q9NYA4
NLLKVYFPDVQFNRC

PROX2

461

Q3B8N5
NAPIVNRFDYAQCKK

FBXO38

966

Q6PIJ6
NPAIYCLRNKEVKEA

OR6P1

286

Q8NGX9
KPLKANQQFLVYCEI

FGG

196

P02679
YLLVSFKCQPNELKN

EVA1C

151

P58658
LYKKFDLRANCEPQT

ETFDH

256

Q16134
YNCELPQNCKEVKRL

ADAMTS9

1731

Q9P2N4
QCYKRALDAQIKNKP

CCDC81

481

Q6ZN84
ALAEFLCLNYKKNPA

CPD

1006

O75976
FDVQKLRIYCDPEQN

COL21A1

401

Q96P44
DPNNIKTNAKLYCNR

DNAJC7

286

Q99615
CRFKDAFQQYPDLLK

DDX53

221

Q86TM3
NERLKKYPNDCQDGL

FAM111B

596

Q6SJ93
KELQSLYRGFKNECP

KCNIP3

91

Q9Y2W7
FNCLYKNPEATFKLI

OLAH

16

Q9NV23
CYNAQAIFKQKLPVA

IL1R1

121

P14778
NPLIYCLRNKEFKDA

OR6B2

286

Q6IFH4
TINYLKQFLCKLREP

FER1L6

1081

Q2WGJ9
EKYLRDVNCPFKIQD

RTRAF

61

Q9Y224
YLFNKSLEIEPRNCK

SOS2

1006

Q07890
LKDQQDVFCFRYKIQ

STAT2

166

P52630
RNEDYKEITQKLCFP

SYNJ2

696

O15056
QAYIDIKNCPKKTRN

F5

321

P12259
CQTFKLYQEQPKLDS

FER1L5

1431

A0AVI2
CNDKLQFEYNEEIPK

PLCE1

1611

Q9P212
YQKFLEGLQKCQRDL

RMI1

571

Q9H9A7
LFCRQYDIIKDNEPN

FNDC5

171

Q8NAU1
PYCVKFNPDEDKQNL

CDC40

376

O60508
LAKFRQCLQENPKFL

PITRM1

471

Q5JRX3
YAQQVLQKECRPKFA

ST3GAL5

111

Q9UNP4
NPLIYCLRNKEFKNA

OR6B3

286

Q8NGW1
HCKFNVPLARLNQKY

ACTRT1

41

Q8TDG2
NILPKCQDQDFLPKY

CCDC15

621

Q0P6D6
LKNFKRCLQLEPYNE

TTC13

371

Q8NBP0
VVDCKKEAFRLQPYN

TIMM50

246

Q3ZCQ8
ERPYKCNECIKTFNQ

ZNF542P

151

Q5EBM4
PKRIYFNKQENCILL

VPS13A

2366

Q96RL7
NIQILKQPFDYNKCG

ZNF334

201

Q9HCZ1
KECQAPKRELNQVLY

ZBP1

36

Q9H171
DLKACNQLPKFYGEL

SCN10A

56

Q9Y5Y9
FQRAKCKDPQLEIAY

SMOC2

66

Q9H3U7
AQVRKAVQYEEKNPC

STX11

261

O75558
FRRCPFLEQEQAKKY

RFX8

156

Q6ZV50
NCELVKKFLDPNNYS

PXK

111

Q7Z7A4
KQKCLYNLPFKRNLE

STAB2

1921

Q8WWQ8
VQYKKFQAREKPNVC

ZNF630

251

Q2M218
NSECLKEQQKRYFPV

SLFN5

366

Q08AF3
VKNDTERKFCYQQLP

UNC79

936

Q9P2D8