Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	aspartic-type endopeptidase activity	ERVK-6 ERVK-7 ERVK-10 ERVK-8 ERVK-19 ERVK-25	6.43e-08	37	115	6	GO:0004190
GeneOntologyMolecularFunction	aspartic-type peptidase activity	ERVK-6 ERVK-7 ERVK-10 ERVK-8 ERVK-19 ERVK-25	7.60e-08	38	115	6	GO:0070001
GeneOntologyMolecularFunction	RNA-DNA hybrid ribonuclease activity	ERVK-6 ERVK-7 ERVK-10 ERVK-8	3.34e-07	11	115	4	GO:0004523
GeneOntologyMolecularFunction	RNA-directed DNA polymerase activity	ERVK-6 ERVK-7 ERVK-10 ERVK-8	9.99e-07	14	115	4	GO:0003964
GeneOntologyMolecularFunction	RNA stem-loop binding	ERVK-6 ERVK-7 ERVK-10 ERVK-8	5.79e-06	21	115	4	GO:0035613
GeneOntologyMolecularFunction	lysine-acetylated histone binding	BRD3 ZZZ3 KMT2A MLLT1	2.55e-05	30	115	4	GO:0070577
GeneOntologyMolecularFunction	acetylation-dependent protein binding	BRD3 ZZZ3 KMT2A MLLT1	2.91e-05	31	115	4	GO:0140033
GeneOntologyMolecularFunction	cytoskeletal protein binding	MAGI1 ABL1 WAS TOM1 VASH1 OBSCN CKAP5 MYLK2 RGS14 NKD2 GAS2L2 FMN1 FARP1 LMOD1 MICAL3 DLEC1 DIAPH3 CDK5R2	5.57e-05	1099	115	18	GO:0008092
GeneOntologyMolecularFunction	RNA endonuclease activity, producing 5'-phosphomonoesters	ERVK-6 ERVK-7 ERVK-10 ERVK-8	5.95e-05	37	115	4	GO:0016891
GeneOntologyMolecularFunction	high voltage-gated calcium channel activity	CACNA1B CACNA1I CACNA1G	6.47e-05	14	115	3	GO:0008331
GeneOntologyMolecularFunction	DNA polymerase activity	ERVK-6 ERVK-7 ERVK-10 ERVK-8	6.62e-05	38	115	4	GO:0034061
GeneOntologyMolecularFunction	low voltage-gated calcium channel activity	CACNA1I CACNA1G	9.83e-05	3	115	2	GO:0008332
GeneOntologyMolecularFunction	endonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters	ERVK-6 ERVK-7 ERVK-10 ERVK-8	1.41e-04	46	115	4	GO:0016893
GeneOntologyMolecularFunction	voltage-gated calcium channel activity	CACNA1B TSPOAP1 CACNA1I CACNA1G	1.41e-04	46	115	4	GO:0005245
GeneOntologyMolecularFunction	nucleoside-triphosphatase regulator activity	TBC1D3E TBC1D3 WAS OBSCN TBC1D3C RGS14 FARP1 ARHGEF26 TBC1D3K TBC1D3F	7.02e-04	507	115	10	GO:0060589
GeneOntologyMolecularFunction	GTPase regulator activity	TBC1D3E TBC1D3 WAS OBSCN TBC1D3C RGS14 FARP1 ARHGEF26 TBC1D3K TBC1D3F	7.02e-04	507	115	10	GO:0030695
GeneOntologyMolecularFunction	structural constituent of presynaptic active zone	PCLO BSN	9.00e-04	8	115	2	GO:0098882
GeneOntologyMolecularFunction	RNA endonuclease activity	ERVK-6 ERVK-7 ERVK-10 ERVK-8	1.12e-03	79	115	4	GO:0004521
GeneOntologyMolecularFunction	voltage-gated calcium channel activity involved in regulation of cytosolic calcium levels	CACNA1B TSPOAP1	1.15e-03	9	115	2	GO:0099511
GeneOntologyMolecularFunction	voltage-gated calcium channel activity involved in regulation of presynaptic cytosolic calcium levels	CACNA1B TSPOAP1	1.15e-03	9	115	2	GO:0099626
GeneOntologyMolecularFunction	DNA secondary structure binding	ABL1 HMGB3 KMT2A	1.69e-03	41	115	3	GO:0000217
GeneOntologyMolecularFunction	actin binding	ABL1 WAS VASH1 GAS2L2 FMN1 LMOD1 MICAL3 DIAPH3 CDK5R2	1.82e-03	479	115	9	GO:0003779
GeneOntologyMolecularFunction	zinc ion binding	ERVK-6 TCEA3 RBBP6 MMP27 ERVK-7 ERVK-10 ZZZ3 AEBP1 ERVK-8 KMT2A ERVK-19 ZFHX3 ST18	1.86e-03	891	115	13	GO:0008270
GeneOntologyMolecularFunction	nucleotidyltransferase activity	ERVK-6 ABL1 ERVK-7 ERVK-10 ERVK-8	1.88e-03	152	115	5	GO:0016779
GeneOntologyMolecularFunction	histone H3 methyltransferase activity	NSD2 SETBP1 KMT2A	2.08e-03	44	115	3	GO:0140938
GeneOntologyMolecularFunction	S-adenosylmethionine-dependent methyltransferase activity	NSD2 METTL14 SETBP1 KMT2A NOP2	3.20e-03	172	115	5	GO:0008757
GeneOntologyMolecularFunction	transition metal ion binding	ERVK-6 TCEA3 CYP2A6 ABL1 RBBP6 MMP27 ERVK-7 ERVK-10 ZZZ3 AEBP1 ERVK-8 KMT2A ERVK-19 ZFHX3 ST18	3.40e-03	1189	115	15	GO:0046914
GeneOntologyMolecularFunction	cadherin binding	DNAJB1 CAST OBSCN CKAP5 TNKS1BP1 DIAPH3 CDH4	3.50e-03	339	115	7	GO:0045296
GeneOntologyBiologicalProcess	DNA integration	ERVK-6 ERVK-7 ERVK-10 ERVK-8	6.09e-07	13	114	4	GO:0015074
GeneOntologyBiologicalProcess	presynaptic active zone organization	PCLO CAST BSN	1.92e-05	10	114	3	GO:1990709
GeneOntologyBiologicalProcess	activation of GTPase activity	TBC1D3E TBC1D3 TBC1D3C ARHGEF26 TBC1D3K TBC1D3F	3.18e-05	109	114	6	GO:0090630
GeneOntologyBiologicalProcess	DNA recombination	ERVK-6 ABL1 WAS NSD2 HMGB3 ERVK-7 ERVK-10 H1-8 RAD54B ERVK-8	3.80e-05	368	114	10	GO:0006310
GeneOntologyBiologicalProcess	protein localization to microtubule end	ABL1 GAS2L2	9.05e-05	3	114	2	GO:1905725
GeneOntologyBiologicalProcess	protein localization to microtubule plus-end	ABL1 GAS2L2	9.05e-05	3	114	2	GO:1904825
GeneOntologyBiologicalProcess	presynapse to nucleus signaling pathway	PCLO BSN	9.05e-05	3	114	2	GO:0099526
GeneOntologyBiologicalProcess	RNA-templated DNA biosynthetic process	ERVK-6 ERVK-7 ERVK-10 ERVK-8 TNKS1BP1	9.73e-05	83	114	5	GO:0006278
GeneOntologyBiologicalProcess	DNA synthesis involved in DNA repair	ERVK-6 ERVK-7 ERVK-10 ERVK-8	1.43e-04	48	114	4	GO:0000731
GeneOntologyBiologicalProcess	positive regulation of calcium ion-dependent exocytosis	CACNA1I CACNA1G CDK5R2	1.75e-04	20	114	3	GO:0045956
GeneOntologyBiologicalProcess	presynaptic signal transduction	PCLO BSN	1.80e-04	4	114	2	GO:0098928
Domain	ZnF_C2HC	ERVK-6 FAM90A14 RBBP6 FAM90A7 FAM90A18 FAM90A9 FAM90A8 FAM90A10	7.45e-10	55	105	8	SM00343
Domain	Znf_CCHC	ERVK-6 FAM90A14 RBBP6 FAM90A7 FAM90A18 FAM90A9 FAM90A8 FAM90A10	7.45e-10	55	105	8	IPR001878
Domain	VDCCAlpha1	CACNA1B CACNA1I CACNA1G	2.01e-05	10	105	3	IPR002077
Domain	Znf_piccolo	PCLO BSN	3.13e-05	2	105	2	IPR008899
Domain	zf-piccolo	PCLO BSN	3.13e-05	2	105	2	PF05715
Domain	VDCC_T_a1	CACNA1I CACNA1G	9.36e-05	3	105	2	IPR005445
Domain	TBC	TBC1D3E TBC1D3C TBC1D3K TBC1D3F	1.64e-04	49	105	4	SM00164
Domain	Znf_FYVE_PHD	NSD2 PCLO DIDO1 KMT2A BSN KDM4B	1.82e-04	147	105	6	IPR011011
Domain	SH3	ABL1 TSPOAP1 SH3KBP1 OBSCN CASKIN1 ARHGEF26 FYB1	2.19e-04	216	105	7	SM00326
Domain	SH3	ABL1 TSPOAP1 SH3KBP1 OBSCN CASKIN1 ARHGEF26 FYB1	2.19e-04	216	105	7	PS50002
Domain	RabGAP-TBC	TBC1D3E TBC1D3C TBC1D3K TBC1D3F	2.23e-04	53	105	4	PF00566
Domain	SH3_domain	ABL1 TSPOAP1 SH3KBP1 OBSCN CASKIN1 ARHGEF26 FYB1	2.45e-04	220	105	7	IPR001452
Domain	TBC_RABGAP	TBC1D3E TBC1D3C TBC1D3K TBC1D3F	2.58e-04	55	105	4	PS50086
Domain	Rab-GTPase-TBC_dom	TBC1D3E TBC1D3C TBC1D3K TBC1D3F	2.58e-04	55	105	4	IPR000195
Domain	TFS2M	TCEA3 DIDO1	6.45e-04	7	105	2	SM00510
Domain	TFIIS_M	TCEA3 DIDO1	6.45e-04	7	105	2	PF07500
Domain	PHD	NSD2 DIDO1 KMT2A KDM4B	8.44e-04	75	105	4	PF00628
Domain	TFIIS_cen_dom	TCEA3 DIDO1	8.57e-04	8	105	2	IPR003618
Domain	-	TCEA3 DIDO1	8.57e-04	8	105	2	1.10.472.30
Domain	TFIIS_CENTRAL	TCEA3 DIDO1	8.57e-04	8	105	2	PS51321
Domain	SH3_2	TSPOAP1 SH3KBP1 CASKIN1 FYB1	1.41e-03	86	105	4	IPR011511
Domain	SH3_2	TSPOAP1 SH3KBP1 CASKIN1 FYB1	1.41e-03	86	105	4	PF07653
Domain	PHD	NSD2 DIDO1 KMT2A KDM4B	1.60e-03	89	105	4	SM00249
Domain	Znf_PHD	NSD2 DIDO1 KMT2A KDM4B	1.73e-03	91	105	4	IPR001965
Domain	ZF_PHD_2	NSD2 DIDO1 KMT2A KDM4B	2.03e-03	95	105	4	PS50016
Domain	ZF_PHD_1	NSD2 DIDO1 KMT2A KDM4B	2.11e-03	96	105	4	PS01359
Domain	WH2	WAS LMOD1	2.73e-03	14	105	2	SM00246
Domain	FH2	FMN1 DIAPH3	3.13e-03	15	105	2	PS51444
Domain	FH2_Formin	FMN1 DIAPH3	3.13e-03	15	105	2	IPR015425
Domain	FH2	FMN1 DIAPH3	3.13e-03	15	105	2	PF02181
Domain	FH2	FMN1 DIAPH3	3.13e-03	15	105	2	SM00498
Domain	Post-SET_dom	NSD2 KMT2A	3.57e-03	16	105	2	IPR003616
Domain	PostSET	NSD2 KMT2A	3.57e-03	16	105	2	SM00508
Domain	WH2	WAS LMOD1	3.57e-03	16	105	2	PF02205
Domain	AT_hook	SETBP1 KMT2A	3.57e-03	16	105	2	PF02178
Domain	POST_SET	NSD2 KMT2A	3.57e-03	16	105	2	PS50868
Domain	-	RBBP6 NSD2 PCLO DIDO1 NOSIP KMT2A BSN KDM4B	3.83e-03	449	105	8	3.30.40.10
Domain	HEAT_type_2	CKAP5 MROH1	4.03e-03	17	105	2	IPR021133
Domain	Hemopexin_CS	MMP27 PRG4	4.03e-03	17	105	2	IPR018486
Domain	Channel_four-helix_dom	CACNA1B CACNA1I CACNA1G	4.05e-03	57	105	3	IPR027359
Domain	-	CACNA1B CACNA1I CACNA1G	4.05e-03	57	105	3	1.20.120.350
Domain	Znf_RING/FYVE/PHD	RBBP6 NSD2 PCLO DIDO1 NOSIP KMT2A BSN KDM4B	4.37e-03	459	105	8	IPR013083
Domain	DH_1	OBSCN FARP1 ARHGEF26	5.37e-03	63	105	3	PS00741
Domain	WH2_dom	WAS LMOD1	6.13e-03	21	105	2	IPR003124
Domain	RhoGEF	OBSCN FARP1 ARHGEF26	6.64e-03	68	105	3	SM00325
Domain	EPHD	KMT2A KDM4B	6.72e-03	22	105	2	PS51805
Pubmed	Characterization and evolution of the novel gene family FAM90A in primates originated by multiple duplication and rearrangement events.	FAM90A14 FAM90A17 FAM90A19 FAM90A22 FAM90A23 FAM90A7 FAM90A18 FAM90A9 FAM90A8 FAM90A16 FAM90A10	1.65e-21	25	117	11	17684299
Pubmed	Analysis of the multi-copy gene family FAM90A as a copy number variant in different ethnic backgrounds.	FAM90A14 FAM90A17 FAM90A19 FAM90A22 FAM90A23 FAM90A7 FAM90A9 FAM90A8 FAM90A16 FAM90A10	1.38e-19	23	117	10	18602769
Pubmed	Placental PPARγ regulates spatiotemporally diverse genes and a unique metabolic network.	FAM90A14 FAM90A17 FAM90A19 FAM90A22 FAM90A26 FAM90A23 DIAPH3 FAM90A7 FAM90A9 FAM90A8 FAM90A10	1.03e-11	164	117	11	22967998
Pubmed	TBC1D3, a hominoid oncoprotein, is encoded by a cluster of paralogues located on chromosome 17q12.	TBC1D3E TBC1D3 TBC1D3C TBC1D3K TBC1D3F	1.80e-10	11	117	5	16863688
Pubmed	The in vivo Interaction Landscape of Histones H3.1 and H3.3.	STAG1 NSD2 DIDO1 HMGB3 BRD3 ZC3H18 WDR43 SCMH1 RAD54B KMT2A ELF1 NOP2 AFF4 KDM4B	1.89e-08	608	117	14	36089195
Pubmed	Prediction of the coding sequences of mouse homologues of KIAA gene: III. the complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.	NSD2 NACA DIDO1 FNDC3A RRBP1 WDR43 METTL14 CASKIN1 SETBP1 TNKS1BP1 CACNA1G BSN KDM4B	2.96e-08	529	117	13	14621295
Pubmed	Large-scale characterization of HeLa cell nuclear phosphoproteins.	RBBP6 CAST CKAP5 DIDO1 BRD3 ZC3H18 ZNF217 RRBP1 KMT2A ELF1 TNKS1BP1 MICAL3 NOP2 PRG4 KDM4B	5.49e-08	774	117	15	15302935
Pubmed	A yeast two-hybrid screen reveals that osteopontin associates with MAP1A and MAP1B in addition to other proteins linked to microtubule stability, apoptosis and protein degradation in the human brain.	DNAJB1 RBBP6 NACA CC2D1B BRD3 AFF4	1.18e-07	68	117	6	22779921
Pubmed	BioID-based intact cell interactome of the Kv1.3 potassium channel identifies a Kv1.3-STAT3-p53 cellular signaling pathway.	MAGI1 DNAJB1 CKAP5 CC2D1B FNDC3A ZC3H18 ATE1 RRBP1 SLC16A1 TNKS1BP1 MICAL3 DIAPH3 ARHGEF26 MED12	1.23e-07	708	117	14	39231216
Pubmed	Many human endogenous retrovirus K (HERV-K) proviruses are unique to humans.	ERVK-6 ERVK-7 ERVK-10	1.48e-07	4	117	3	10469592
Pubmed	Human endogenous retrovirus K10: expression of Gag protein and detection of antibodies in patients with seminomas.	ERVK-6 ERVK-10 ERVK-19	1.48e-07	4	117	3	7983737
Pubmed	Quantitation of HERV-K env gene expression and splicing in human breast cancer.	ERVK-6 ERVK-7 ERVK-19	3.69e-07	5	117	3	12629516
Pubmed	The RNA-mediated estrogen receptor α interactome of hormone-dependent human breast cancer cell nuclei.	DNAJB1 RBBP6 NSD2 NACA TOM1 CKAP5 DIDO1 BRD3 ZNF217 MYLK2 WDR43 METTL14 FARP1 CRACDL KMT2A MLLT1 ZFHX3 MED12 AFF4	6.15e-07	1497	117	19	31527615
Pubmed	A revised nomenclature for transcribed human endogenous retroviral loci.	ERVK-6 ERVK-7 ERVK-10 ERVK-8 ERVK-19 ERVK-25	8.15e-07	94	117	6	21542922
Pubmed	Fyn-binding protein (Fyb)/SLP-76-associated protein (SLAP), Ena/vasodilator-stimulated phosphoprotein (VASP) proteins and the Arp2/3 complex link T cell receptor (TCR) signaling to the actin cytoskeleton.	WAS LCP2 FYB1	1.29e-06	7	117	3	10747096
Pubmed	In-Depth In Vivo Crosslinking in Minutes by a Compact, Membrane-Permeable, and Alkynyl-Enrichable Crosslinker.	CYP2A6 STAG1 NSD2 PCLO CC2D1B HMGB3 BRD3 RRBP1 FER1L6 MYLK2 RGS14 KMT2A MLLT1 DLEC1 DIAPH3 BSN CDK5R2 ZNF541	1.59e-06	1442	117	18	35575683
Pubmed	Evolutionary insights into T-type Ca2+ channel structure, function, and ion selectivity from the Trichoplax adhaerens homologue.	CACNA1B CACNA1I CACNA1G	2.05e-06	8	117	3	28330839
Pubmed	Menin and Menin-Associated Proteins Coregulate Cancer Energy Metabolism.	STAG1 RBBP6 DIDO1 ZC3H18 KMT2A TNKS1BP1 NOP2 MED12 AFF4	2.46e-06	341	117	9	32971831
Pubmed	Qualitative and quantitative analyses of protein phosphorylation in naive and stimulated mouse synaptosomal preparations.	CACNA1B PCLO SH3KBP1 AMER2 SLC16A1 CASKIN1 TNKS1BP1 MICAL3 BSN	2.83e-06	347	117	9	17114649
Pubmed	International Union of Pharmacology. XLVIII. Nomenclature and structure-function relationships of voltage-gated calcium channels.	CACNA1B CACNA1I CACNA1G	3.07e-06	9	117	3	16382099
Pubmed	The Nse5/6-like SIMC1-SLF2 complex localizes SMC5/6 to viral replication centers.	RBBP6 NSD2 CAST DIDO1 HMGB3 ZC3H18 RRBP1 WDR43 NOSIP ZZZ3 KMT2A MLLT1 NOP2 AFF4	4.17e-06	954	117	14	36373674
Pubmed	A higher-order complex containing AF4 and ENL family proteins with P-TEFb facilitates oncogenic and physiologic MLL-dependent transcription.	KMT2A MLLT1 AFF4	4.38e-06	10	117	3	20153263
Pubmed	The HECT type ubiquitin ligase NEDL2 is degraded by anaphase-promoting complex/cyclosome (APC/C)-Cdh1, and its tight regulation maintains the metaphase to anaphase transition.	RBBP6 DIDO1 NOSIP ZZZ3 RAD54B KMT2A MED12 AFF4	5.24e-06	281	117	8	24163370
Pubmed	Mapping the Ku Interactome Using Proximity-Dependent Biotin Identification in Human Cells.	DNAJB1 RBBP6 DIDO1 ZC3H18 WDR43 ZFHX3 NOP2 AFF4	5.52e-06	283	117	8	30585729
Pubmed	Neuron-specific protein network mapping of autism risk genes identifies shared biological mechanisms and disease-relevant pathologies.	CACNA1B TSPOAP1 PCLO NACA SH3KBP1 CKAP5 ATE1 RRBP1 NHSL1 AMER2 SLC16A1 FARP1 CASKIN1 TMCC2 BSN	6.80e-06	1139	117	15	36417873
Pubmed	Genomewide screening for fusogenic human endogenous retrovirus envelopes identifies syncytin 2, a gene conserved on primate evolution.	ERVK-6 ERVK-8 ERVK-19	7.98e-06	12	117	3	14557543
Pubmed	Regulatory Mechanisms of Prg4 and Gdf5 Expression in Articular Cartilage and Functions in Osteoarthritis.	GDF5 PRG4	1.12e-05	2	117	2	35563063
Pubmed	Bassoon and Piccolo maintain synapse integrity by regulating protein ubiquitination and degradation.	PCLO BSN	1.12e-05	2	117	2	23403927
Pubmed	Multipoint binding of the SLP-76 SH2 domain to ADAP is critical for oligomerization of SLP-76 signaling complexes in stimulated T cells.	LCP2 FYB1	1.12e-05	2	117	2	23979596
Pubmed	Functional association between SLAP-130 and SLP-76 in Jurkat T cells.	LCP2 FYB1	1.12e-05	2	117	2	10671560
Pubmed	The ENL YEATS epigenetic reader domain critically links MLL-ENL to leukemic stem cell frequency in t(11;19) Leukemia.	KMT2A MLLT1	1.12e-05	2	117	2	36435883
Pubmed	Spliced MLL fusions: a novel mechanism to generate functional chimeric MLL-MLLT1 transcripts in t(11;19)(q23;p13.3) leukemia.	KMT2A MLLT1	1.12e-05	2	117	2	17252016
Pubmed	Role of Bassoon and Piccolo in Assembly and Molecular Organization of the Active Zone.	PCLO BSN	1.12e-05	2	117	2	26793095
Pubmed	Clinical outcome and monitoring of minimal residual disease in patients with acute lymphoblastic leukemia expressing the MLL/ENL fusion gene.	KMT2A MLLT1	1.12e-05	2	117	2	21953510
Pubmed	Piccolo and bassoon maintain synaptic vesicle clustering without directly participating in vesicle exocytosis.	PCLO BSN	1.12e-05	2	117	2	20332206
Pubmed	Expression of human endogenous retrovirus type K envelope glycoprotein in insect and mammalian cells.	ERVK-6 ERVK-19	1.12e-05	2	117	2	9060628
Pubmed	Contribution of postsynaptic T-type calcium channels to parallel fibre-Purkinje cell synaptic responses.	CACNA1I CACNA1G	1.12e-05	2	117	2	26627919
Pubmed	Two distinct portions of LTG19/ENL at 19p13 are involved in t(11;19) leukemia.	KMT2A MLLT1	1.12e-05	2	117	2	8378076
Pubmed	Evolutionary relationships within a subgroup of HERV-K-related human endogenous retroviruses.	ERVK-6 ERVK-19	1.12e-05	2	117	2	9460924
Pubmed	Active zone density is conserved during synaptic growth but impaired in aged mice.	PCLO BSN	1.12e-05	2	117	2	21935939
Pubmed	The SLP-76 Src homology 2 domain is required for T cell development and activation.	LCP2 FYB1	1.12e-05	2	117	2	21949020
Pubmed	Acute myeloid leukemia induced by MLL-ENL is cured by oncogene ablation despite acquisition of complex genetic abnormalities.	KMT2A MLLT1	1.12e-05	2	117	2	19029444
Pubmed	ADAP is an upstream regulator that precedes SLP-76 at sites of TCR engagement and stabilizes signaling microclusters.	LCP2 FYB1	1.12e-05	2	117	2	30305305
Pubmed	Activity-dependent gating of calcium spikes by A-type K+ channels controls climbing fiber signaling in Purkinje cell dendrites.	GRM1 CACNA1G	1.12e-05	2	117	2	25220810
Pubmed	Differential requirement for adapter proteins Src homology 2 domain-containing leukocyte phosphoprotein of 76 kDa and adhesion- and degranulation-promoting adapter protein in FcepsilonRI signaling and mast cell function.	LCP2 FYB1	1.12e-05	2	117	2	15153494
Pubmed	ADAP-SLP-76 binding differentially regulates supramolecular activation cluster (SMAC) formation relative to T cell-APC conjugation.	LCP2 FYB1	1.12e-05	2	117	2	15477347
Pubmed	Molecular cloning of SLAP-130, an SLP-76-associated substrate of the T cell antigen receptor-stimulated protein tyrosine kinases.	LCP2 FYB1	1.12e-05	2	117	2	9115214
Pubmed	Dual-color STED microscopy reveals a sandwich structure of Bassoon and Piccolo in active zones of adult and aged mice.	PCLO BSN	1.12e-05	2	117	2	27321892
Pubmed	No symphony without bassoon and piccolo: changes in synaptic active zone proteins in Huntington's disease.	PCLO BSN	1.12e-05	2	117	2	32493491
Pubmed	Novel isoform of lymphoid adaptor FYN-T-binding protein (FYB-130) interacts with SLP-76 and up-regulates interleukin 2 production.	LCP2 FYB1	1.12e-05	2	117	2	10497204
Pubmed	Synaptic activity controls localization and function of CtBP1 via binding to Bassoon and Piccolo.	PCLO BSN	1.12e-05	2	117	2	25652077
Pubmed	Construction of expression-ready cDNA clones for KIAA genes: manual curation of 330 KIAA cDNA clones.	FNDC3A RRBP1 TMCC2 SETBP1 TNKS1BP1 CACNA1G KDM4B	1.17e-05	225	117	7	12168954
Pubmed	Calcium channels link the muscle-derived synapse organizer laminin β2 to Bassoon and CAST/Erc2 to organize presynaptic active zones.	CACNA1B PCLO BSN	1.31e-05	14	117	3	21228161
Pubmed	MLL-AF9 and MLL-ENL alter the dynamic association of transcriptional regulators with genes critical for leukemia.	KMT2A MLLT1 AFF4	1.31e-05	14	117	3	20854876
Pubmed	SRCAP complex promotes lung cancer progression by reprograming the oncogenic transcription of Hippo-YAP/TAZ signaling pathway.	DNAJB1 RBBP6 CAST DIDO1 ZZZ3 SLC16A1 KMT2A TNKS1BP1 DIAPH3 MED12	1.74e-05	549	117	10	38280479
Pubmed	A dual-activity topoisomerase complex regulates mRNA translation and turnover.	ABL1 NSD2 OBSCN PPP1R26 NHSL1 MROH1 PLEKHO2 CASKIN1 TMCC2 MLLT1 TNKS1BP1 MICAL3 BCL2L13 MED12	2.16e-05	1105	117	14	35748872
Pubmed	E-cadherin interactome complexity and robustness resolved by quantitative proteomics.	MAGI1 DNAJB1 SH3KBP1 CAST CKAP5 NHSL1 PLEKHO2 FMN1 TNKS1BP1 DIAPH3	2.23e-05	565	117	10	25468996
Pubmed	NuRD subunit CHD4 regulates super-enhancer accessibility in rhabdomyosarcoma and represents a general tumor dependency.	RBBP6 BRD3 ZC3H18 KMT2A ZFHX3	2.66e-05	103	117	5	32744500
Pubmed	A conserved arginine-containing motif crucial for the assembly and enzymatic activity of the mixed lineage leukemia protein-1 core complex.	KMT2A MLLT1	3.36e-05	3	117	2	18829457
Pubmed	Structure of WDR5 bound to mixed lineage leukemia protein-1 peptide.	KMT2A MLLT1	3.36e-05	3	117	2	18829459
Pubmed	Ethanol inhibition of a T-type Ca²+ channel through activity of protein kinase C.	CACNA1I CACNA1G	3.36e-05	3	117	2	23488970
Pubmed	T-type channels: release a brake, engage a gear.	CACNA1I CACNA1G	3.36e-05	3	117	2	26488564
Pubmed	BCR-ABL1-induced downregulation of WASP in chronic myeloid leukemia involves epigenetic modification and contributes to malignancy.	ABL1 WAS	3.36e-05	3	117	2	29022901
Pubmed	Differential interactions of Na+ channel toxins with T-type Ca2+ channels.	CACNA1I CACNA1G	3.36e-05	3	117	2	18591418
Pubmed	Identification of the t-type calcium channel (Ca(v)3.1d) in developing mouse heart.	CACNA1I CACNA1G	3.36e-05	3	117	2	11230107
Pubmed	Prognostic relevance of a T-type calcium channels gene signature in solid tumours: A correlation ready for clinical validation.	CACNA1I CACNA1G	3.36e-05	3	117	2	28846697
Pubmed	The secreted glycoprotein lubricin protects cartilage surfaces and inhibits synovial cell overgrowth.	GDF5 PRG4	3.36e-05	3	117	2	15719068
Pubmed	Engineering de novo reciprocal chromosomal translocations associated with Mll to replicate primary events of human cancer.	KMT2A MLLT1	3.36e-05	3	117	2	12781363
Pubmed	Homeostatic plasticity and burst activity are mediated by hyperpolarization-activated cation currents and T-type calcium channels in neuronal cultures.	CACNA1I CACNA1G	3.36e-05	3	117	2	33547341
Pubmed	Retrovirus-mediated gene transfer of MLL-ELL transforms primary myeloid progenitors and causes acute myeloid leukemias in mice.	KMT2A MLLT1	3.36e-05	3	117	2	10995463
Pubmed	Calmodulin regulates Cav3 T-type channels at their gating brake.	CACNA1I CACNA1G	3.36e-05	3	117	2	28972185
Pubmed	Genome-wide screening, cloning, chromosomal assignment, and expression of full-length human endogenous retrovirus type K.	ERVK-6 ERVK-19	3.36e-05	3	117	2	10516026
Pubmed	Global genetic deletion of CaV3.3 channels facilitates anaesthetic induction and enhances isoflurane-sparing effects of T-type calcium channel blockers.	CACNA1I CACNA1G	3.36e-05	3	117	2	33299036
Pubmed	Cloning of a novel T-cell protein FYB that binds FYN and SH2-domain-containing leukocyte protein 76 and modulates interleukin 2 production.	LCP2 FYB1	3.36e-05	3	117	2	9207119
Pubmed	Simultaneous localization of MLL, AF4 and ENL genes in interphase nuclei by 3D-FISH: MLL translocation revisited.	KMT2A MLLT1	3.36e-05	3	117	2	16433901
Pubmed	Specific contribution of human T-type calcium channel isotypes (alpha(1G), alpha(1H) and alpha(1I)) to neuronal excitability.	CACNA1I CACNA1G	3.36e-05	3	117	2	11927664
Pubmed	Positive and negative regulation by SLP-76/ADAP and Pyk2 of chemokine-stimulated T-lymphocyte adhesion mediated by integrin α4β1.	LCP2 FYB1	3.36e-05	3	117	2	26202465
Pubmed	Dynamic molecular interactions linking the T cell antigen receptor to the actin cytoskeleton.	WAS LCP2	3.36e-05	3	117	2	15558067
Pubmed	Growth differentiation factor-15 promotes glutamate release in medial prefrontal cortex of mice through upregulation of T-type calcium channels.	CACNA1I CACNA1G	3.36e-05	3	117	2	27353765
Pubmed	Cutting edge: SLP-76 cooperativity with FYB/FYN-T in the Up-regulation of TCR-driven IL-2 transcription requires SLP-76 binding to FYB at Tyr595 and Tyr651.	LCP2 FYB1	3.36e-05	3	117	2	10570256
Pubmed	Alpha(1H) mRNA in single skeletal muscle fibres accounts for T-type calcium current transient expression during fetal development in mice.	CACNA1I CACNA1G	3.36e-05	3	117	2	11897840
Pubmed	A mutation within the SH2 domain of slp-76 regulates the tissue distribution and cytokine production of iNKT cells in mice.	LCP2 FYB1	3.36e-05	3	117	2	27349342
Pubmed	Three-way translocation involving MLL, MLLT1, and a novel third partner, NRXN1, in a patient with acute lymphoblastic leukemia and t(2;19;11) (p12;p13.3;q23).	KMT2A MLLT1	3.36e-05	3	117	2	20113834
Pubmed	Involvement of a homolog of Drosophila trithorax by 11q23 chromosomal translocations in acute leukemias.	KMT2A MLLT1	3.36e-05	3	117	2	1423624
Pubmed	AF5q31, a newly identified AF4-related gene, is fused to MLL in infant acute lymphoblastic leukemia with ins(5;11)(q31;q13q23).	KMT2A AFF4	3.36e-05	3	117	2	10588740
Pubmed	Importance of a specific amino acid pairing for murine MLL leukemias driven by MLLT1/3 or AFF1/4.	MLLT1 AFF4	6.70e-05	4	117	2	25282333
Pubmed	Regulatory T cells require TCR signaling for their suppressive function.	LCP2 FYB1	6.70e-05	4	117	2	25821220
Pubmed	Murine natural killer immunoreceptors use distinct proximal signaling complexes to direct cell function.	LCP2 FYB1	6.70e-05	4	117	2	23407547
Pubmed	Hematopoietic stem cells are intrinsically protected against MLL-ENL-mediated transformation.	KMT2A MLLT1	6.70e-05	4	117	2	25456127
Pubmed	PRC17, a novel oncogene encoding a Rab GTPase-activating protein, is amplified in prostate cancer.	TBC1D3 TBC1D3F	6.70e-05	4	117	2	12359748
Pubmed	Pharmacogenetics of antiepileptic drug efficacy in childhood absence epilepsy.	CACNA1I CACNA1G	6.70e-05	4	117	2	28165634
Pubmed	The Bcr-Abl kinase regulates the actin cytoskeleton via a GADS/Slp-76/Nck1 adaptor protein pathway.	ABL1 LCP2	6.70e-05	4	117	2	20079431
Pubmed	SH2 domain containing leukocyte phosphoprotein of 76-kDa (SLP-76) feedback regulation of ZAP-70 microclustering.	LCP2 FYB1	6.70e-05	4	117	2	20534575
Pubmed	Identification of novel sequences in the repertoire of hypervariable TRE17 genes from immortalized nonmalignant and malignant human keratinocytes.	TBC1D3 TBC1D3F	6.70e-05	4	117	2	8406013
Pubmed	Prognostic impact of KMT2A-AFF1-positivity in 926 BCR-ABL1-negative B-lineage acute lymphoblastic leukemia patients treated in GIMEMA clinical trials since 1996.	ABL1 KMT2A	6.70e-05	4	117	2	34048072
Pubmed	Synovial joint cavitation initiates with microcavities in interzone and is coupled to skeletal flexion and elongation in developing mouse embryo limbs.	GDF5 PRG4	6.70e-05	4	117	2	35608281
Pubmed	Functional coupling between mGluR1 and Cav3.1 T-type calcium channels contributes to parallel fiber-induced fast calcium signaling within Purkinje cell dendritic spines.	GRM1 CACNA1G	6.70e-05	4	117	2	19657020
Pubmed	HPK1 competes with ADAP for SLP-76 binding and via Rap1 negatively affects T-cell adhesion.	LCP2 FYB1	6.70e-05	4	117	2	20957749
Pubmed	Mll fusions generated by Cre-loxP-mediated de novo translocations can induce lineage reassignment in tumorigenesis.	KMT2A MLLT1	6.70e-05	4	117	2	16096649
Pubmed	HIV-1 Tat recruits transcription elongation factors dispersed along a flexible AFF4 scaffold.	MLLT1 AFF4	6.70e-05	4	117	2	23251033
Interaction	KCNA3 interactions	CACNA1B MAGI1 DNAJB1 RBBP6 NACA CKAP5 CC2D1B FNDC3A ZC3H18 ATE1 RRBP1 SLC16A1 KMT2A TNKS1BP1 MICAL3 DIAPH3 BSN ARHGEF26 MED12	6.65e-08	871	102	19	int:KCNA3
Interaction	PSIP1 interactions	GDF5 SH3KBP1 CAST HMGB3 BRD3 ZC3H18 METTL14 SETBP1 KMT2A	9.90e-07	205	102	9	int:PSIP1
Interaction	H3C3 interactions	STAG1 NSD2 DIDO1 HMGB3 BRD3 ZC3H18 WDR43 SCMH1 RAD54B KMT2A NOP2 AFF4 KDM4B	1.29e-06	495	102	13	int:H3C3
Interaction	H2BC9 interactions	PCLO CKAP5 CC2D1B RRBP1 H1-8 ZNF469 SETBP1 NOP2 ST18 CDK5R2 AFF4	1.61e-05	446	102	11	int:H2BC9
Interaction	SPP1 interactions	DNAJB1 RBBP6 NACA CC2D1B BRD3 AFF4	2.49e-05	114	102	6	int:SPP1
Interaction	H2BC21 interactions	SFRP4 NSD2 PCLO OBSCN DIDO1 CC2D1B ZC3H18 ZZZ3 KMT2A MLLT1 FYB1 NOP2 CDK5R2	4.92e-05	696	102	13	int:H2BC21
Cytoband	8p23.1	FAM90A14 FAM90A17 FAM90A19 FAM90A22 ERVK-8 FAM90A23 FAM90A7 FAM90A18 FAM90A9 FAM90A8 FAM90A16 FAM90A10	6.69e-15	154	116	12	8p23.1
Cytoband	Ensembl 112 genes in cytogenetic band chr8p23	FAM90A14 FAM90A17 FAM90A19 FAM90A22 FAM90A23 FAM90A7 FAM90A18 FAM90A9 FAM90A8 FAM90A16 FAM90A10	2.34e-11	234	116	11	chr8p23
Cytoband	Ensembl 112 genes in cytogenetic band chr17q12	TBC1D3E TBC1D3 TBC1D3C GAS2L2 TBC1D3K TBC1D3F	2.34e-06	149	116	6	chr17q12
Cytoband	17q12	TBC1D3 TBC1D3C GAS2L2 TBC1D3F	1.21e-04	99	116	4	17q12
GeneFamily	Calcium voltage-gated channel subunits	CACNA1B CACNA1I CACNA1G	9.90e-05	26	63	3	253
GeneFamily	Pleckstrin homology domain containing\|Rho guanine nucleotide exchange factors\|C2 domain containing	PCLO CC2D1B INPP4B	2.65e-04	36	63	3	823
GeneFamily	AF4/FMR2 family\|Super elongation complex	MLLT1 AFF4	4.23e-04	9	63	2	1280
GeneFamily	Zinc fingers\|Zinc fingers PARP-type\|Poly(ADP-ribose) polymerases	PCLO BSN	1.22e-03	15	63	2	26
GeneFamily	Pleckstrin homology domain containing\|Rho guanine nucleotide exchange factors\|C2 domain containing	OBSCN FARP1 ARHGEF26	1.58e-03	66	63	3	722
GeneFamily	Ataxins\|Trinucleotide repeat containing	MAGI1 MED12	3.40e-03	25	63	2	775
GeneFamily	PHD finger proteins	NSD2 DIDO1 KMT2A	3.82e-03	90	63	3	88
GeneFamily	Pleckstrin homology domain containing\|Rho guanine nucleotide exchange factors\|C2 domain containing	PLEKHO2 FARP1 ARHGEF26 PLEKHO1	5.77e-03	206	63	4	682
GeneFamily	Zinc fingers C2H2-type\|Lysine methyltransferases\|PR/SET domain family	NSD2 KMT2A	6.24e-03	34	63	2	487
Coexpression	GSE22886_NAIVE_CD4_TCELL_VS_NKCELL_UP	DNAJB1 TOM1 OBSCN INPP4B NOSIP RGS14 SCMH1 CACNA1I	8.76e-07	196	100	8	M4423
ToppCell	PBMC_fresh-frozen-Mild-Moderate_convalescent_d36-51-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD4_c06-NR4A2\|Mild-Moderate_convalescent_d36-51 / Compartment, severity and other cell annotations on 10x 3' data (130k)	TCEA3 DNAJB1 INPP4B NOSIP FMN1 CACNA1I FYB1	1.97e-07	182	101	7	9ba85f621a846531a2a7861e9df695d288c9e149
ToppCell	PBMC_fresh-frozen-Severe-critical_progression_d03-09-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD4_c01-LEF1\|Severe-critical_progression_d03-09 / Compartment, severity and other cell annotations on 10x 3' data (130k)	TCEA3 OBSCN INPP4B NOSIP KMT2A CACNA1I FYB1	2.12e-07	184	101	7	5350b58aa9979631228835d11eb45ddf81d08bff
ToppCell	TCGA-Colorectal-Primary_Tumor-Colorectal_Adenocarcinoma-Colon_Adenocarcinoma-7\|TCGA-Colorectal / Sample_Type by Project: Shred V9	SFRP4 DIDO1 ZNF217 ZNF469 AEBP1 FARP1 ELF1	2.46e-07	188	101	7	14bc73cf79c79c9f208369fd8d498e5b26e0114d
ToppCell	healthy_donor-Lymphocytic-T_cell\|healthy_donor / Disease condition, Lineage, Cell class and subclass	TCEA3 DNAJB1 OBSCN INPP4B NOSIP KMT2A FYB1	3.37e-07	197	101	7	63d0f06e150e7eb800ecb70e97b9d12a01c84e37
ToppCell	10x_3'_v3-lymph_node_(10x_3'_v3)-lymphocytic-T_lymphocytic-T_cell\|lymph_node_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type	TCEA3 DNAJB1 NACA LCP2 INPP4B NOSIP FYB1	3.37e-07	197	101	7	076fc05b32200e0a8a1e35d03c295111468d92a9
ToppCell	PND10-Immune-Immune_Lymphocytic_T/NK-Lymphocytic_T-Treg\|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	WAS SH3KBP1 LCP2 INPP4B H1-8 FYB1	2.26e-06	167	101	6	a8fd410967447a95b6c0f6878e6ce614eadb3291
ToppCell	PND10-Immune-Immune_Lymphocytic_T/NK-Lymphocytic_T-Treg-Treg_G2M\|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	CKAP5 E2F2 LCP2 H1-8 DIAPH3 FYB1	2.97e-06	175	101	6	9de288c338cee67be0e9b836c87799bbc1db1c38
ToppCell	PBMC_fresh-frozen-Severe-critical_progression_d12-22_no-steroids-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD4_c01-LEF1\|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)	TCEA3 DNAJB1 INPP4B NOSIP CACNA1I FYB1	3.84e-06	183	101	6	f2ef110bf29b1a8276ef216238363e542db262c1
ToppCell	PBMC_fresh-frozen-Severe-critical_progression_d12-22_no-steroids-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD4_c05-FOS\|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)	TCEA3 DNAJB1 INPP4B NOSIP CACNA1I FYB1	4.21e-06	186	101	6	c793a3d5709ad504c12fc3b2337746d90236d3ca
ToppCell	PBMC_fresh-frozen-Severe-critical_progression_d12-22_no-steroids-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell\|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)	TCEA3 DNAJB1 INPP4B NOSIP CACNA1I FYB1	4.62e-06	189	101	6	9ab77c6fcb573854da5922412f53d2168bda6b58
ToppCell	PBMC_fresh-frozen-Severe-critical_progression_d03-09-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell\|Severe-critical_progression_d03-09 / Compartment, severity and other cell annotations on 10x 3' data (130k)	TCEA3 DNAJB1 INPP4B NOSIP CACNA1I FYB1	4.91e-06	191	101	6	d9a6f61fcda4f5352488f7f55cb9b57aeacc717f
ToppCell	PBMC_fresh-frozen-Mild-Moderate_convalescent_d36-51-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD4_c01-LEF1\|Mild-Moderate_convalescent_d36-51 / Compartment, severity and other cell annotations on 10x 3' data (130k)	TCEA3 NACA INPP4B NOSIP CACNA1I FYB1	4.91e-06	191	101	6	fda432a7f79664e8ffd5d03c1c69ec43bbac994b
ToppCell	PBMC_fresh-frozen-Mild-Moderate_convalescent_d36-51-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD4_c03-ITGA4\|Mild-Moderate_convalescent_d36-51 / Compartment, severity and other cell annotations on 10x 3' data (130k)	TCEA3 DNAJB1 INPP4B NOSIP FMN1 FYB1	5.21e-06	193	101	6	194b49c152e3e3f599068ec88a7f0af6427b743a
ToppCell	T/NK_cells-CD4+_Naive_T_cell\|World / Lineage and Cell class	TCEA3 DNAJB1 NACA INPP4B NOSIP FYB1	5.36e-06	194	101	6	4c6cdedf35c5416a52cb931637715b23d5d07996
ToppCell	PBMC_fresh-frozen-Mild-Moderate_progression_d12-25-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell\|Mild-Moderate_progression_d12-25 / Compartment, severity and other cell annotations on 10x 3' data (130k)	DNAJB1 INPP4B NOSIP FMN1 CACNA1I FYB1	5.36e-06	194	101	6	a44be2f021cfdd0fcdc698c3f04d66db7a1aa6c2
ToppCell	5'-GW_trimst-2-SmallIntestine-Hematopoietic-T_cells-SELL+_CD4_T\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	WAS LCP2 INPP4B NOSIP RGS14 FYB1	5.52e-06	195	101	6	8687b319f1f487fbef4ca075fad054751a641de6
ToppCell	droplet-Thymus-nan-18m-Lymphocytic-thymocyte\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	NSD2 SELENOH CKAP5 HMGB3 E2F2 SLC16A1	5.52e-06	195	101	6	043e2f19d95e94cd5219e2c415f322ed340aa80f
ToppCell	healthy_donor-Lymphocytic-T_cell-CD4+_Naive_T_cell\|healthy_donor / Disease condition, Lineage, Cell class and subclass	TCEA3 OBSCN INPP4B NOSIP CACNA1I FYB1	5.86e-06	197	101	6	cf72160f03105876641fa6fdc7405e339eb084c7
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Immune-Myeloid-Monocytic-Monocyte-derived_Cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	SH3KBP1 VASH1 LCP2 FYB1 PLEKHO1 ST18	5.86e-06	197	101	6	57dafb3047745a44b2345b8036e159c3641d496e
ToppCell	10x_3'_v3-thymus_(10x_3'_v3)-lymphocytic-T_lymphocytic-CD4-positive_helper_T_cell\|thymus_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type	DNAJB1 LCP2 INPP4B NOSIP CACNA1I FYB1	6.03e-06	198	101	6	c4d8d133e571ad3a7c5de93aa7befb67cb7a003d
ToppCell	BALF-PFMC-Severe-critical_progression_d12-22_no-steroids-Myeloid-Granulocytic-Neutrophil-Neu_c6-FGF23\|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)	WAS CMTM2 TOM1 LCP2 FYB1	1.18e-05	130	101	5	793c42602dde22da0715a5304ea70d791fdd5354
ToppCell	IIH-CD4-proli_CD4\|IIH / Condition, Cell_class and T cell subcluster	TCEA3 OBSCN INPP4B NOSIP RAD54B	1.58e-05	138	101	5	e474a0785a651020156baacbf89c4d2b1e4cc473
ToppCell	facs-Lung-nan-3m-Myeloid-Intermediate_Monocyte\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	LCP2 RGS14 FMN1 TMEM131 FYB1	2.85e-05	156	101	5	3f0b9e35d4da85c90759b930052e5b9c3cde9b15
ToppCell	facs-Lung-nan-3m-Myeloid-intermediate_monocyte\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	LCP2 RGS14 FMN1 TMEM131 FYB1	2.85e-05	156	101	5	69e6e8810d1738a66c9821910f41498931cf30cc
ToppCell	severe_influenza-CD4+_T_naive\|severe_influenza / disease group, cell group and cell class (v2)	MAGI1 TCEA3 INPP4B NOSIP AEBP1	3.03e-05	158	101	5	ff3fa4bd06e01363429aec4bb587b95819bf0fc9
ToppCell	facs-Pancreas-Exocrine-18m-Hematologic-nan\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	WAS LCP2 RGS14 PLEKHO2 FYB1	3.31e-05	161	101	5	16f77e7a5444d2f2b210362816cd7a07b9b42af6
ToppCell	facs-Pancreas-Exocrine-18m-Hematologic\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	WAS LCP2 RGS14 PLEKHO2 FYB1	3.31e-05	161	101	5	f5821f551cf5c64c9f75cdb723492c87aac1ece0
ToppCell	facs-Pancreas-Exocrine-18m-Hematologic-leukocyte\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	WAS LCP2 RGS14 PLEKHO2 FYB1	3.31e-05	161	101	5	58a32a1033f379579697bda1bbf047a088e4a34f
ToppCell	PBMC_fresh-frozen-Severe-critical_progression_d03-09-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD4_c02-AQP3\|Severe-critical_progression_d03-09 / Compartment, severity and other cell annotations on 10x 3' data (130k)	TCEA3 DNAJB1 INPP4B NOSIP PRG4	4.06e-05	168	101	5	1dfe87129fdf4cef71dbc17cf39692f0b8dc3345
ToppCell	AT1-AT2_cells-Donor_03\|World / lung cells shred on cell class, cell subclass, sample id	MAGI1 PCLO TBC1D3C CCDC85A ARHGEF26	4.17e-05	169	101	5	815474855a70498a74e52f6583113c63b7267a0c
ToppCell	PND14-Endothelial-Endothelial_blood-vessel-Microvascular_EC-EPC-EPC_prolif\|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	NSD2 CKAP5 CASKIN1 RAD54B DIAPH3	4.54e-05	172	101	5	2b6cd84c946b1e800caba452ae70145ea285fec1
ToppCell	Control-Epithelial_cells-AT1\|Control / group, cell type (main and fine annotations)	MAGI1 CCDC85A FARP1 DIAPH3 ARHGEF26	4.79e-05	174	101	5	548d7f2b958a2bfd2c95eb049ceaab55a559c77d
ToppCell	facs-Marrow-Granulocytes-24m-Hematologic-MPP_Fraction_B\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	IQCD H1-8 FMN1 DIAPH3 ST18	5.20e-05	177	101	5	4a697866ed542d3201714234cee03451adf1dcc9
ToppCell	PND10-Immune-Immune_Lymphocytic_T/NK-Lymphocytic_T-CD4_T\|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	SH3KBP1 LCP2 INPP4B ELF1 FYB1	5.20e-05	177	101	5	13f22e578728be477b097889af483b1e3f3e18bb
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast-kidney_interstitial_fibroblast_5\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	INPP4B NKD2 AEBP1 SETBP1 LMOD1	5.34e-05	178	101	5	78a0c6340001a77f5b2d890b6263f574af2e72da
ToppCell	PND10-Immune-Immune_Lymphocytic_T/NK-Lymphocytic_T-CD4_T-CD4_T_mature\|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	SH3KBP1 LCP2 INPP4B ELF1 FYB1	5.48e-05	179	101	5	8498f94202434b3cb5d84f1a37d3ad191baf664e
ToppCell	Control-Developping_Plasmablast\|Control / disease group and sub_cluster of B and Plasma cells(res = 0.5)	NSD2 HMGB3 E2F2 MYLK2 DIAPH3	5.48e-05	179	101	5	9383568f78b07b8cca72ece5d15fea209aa54ea9
ToppCell	droplet-Bladder-BLADDER-1m-Epithelial-endothelial_cell\|Bladder / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PPP1R26 NKD2 SLC16A1 DIAPH3 ARHGEF26	5.48e-05	179	101	5	c7c74e26bbf86c5326ee38bac7de111d5414f46b
ToppCell	PND14-Endothelial-Endothelial_blood-vessel-Microvascular_EC-EPC-EPC_G2M\|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	SFRP4 NSD2 SELENOH CKAP5 DIAPH3	5.63e-05	180	101	5	5e1680088065be14447d5d5465f91f7edd071a1e
ToppCell	facs-Heart-RV-24m-Mesenchymal-smooth_muscle_cell\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	INPP4B ZZZ3 CASKIN1 LMOD1 CACNA1G	5.63e-05	180	101	5	a37cc885fe3f6cb9df69d43358064c83c18412e7
ToppCell	facs-Heart-RV-24m-Mesenchymal-smooth_muscle_cell\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	INPP4B ZZZ3 CASKIN1 LMOD1 CACNA1G	5.63e-05	180	101	5	63a6d532b16b8b15c7c9102148d7297ee3afd641
ToppCell	PBMC_fresh-frozen-Severe-critical_progression_d12-22_no-steroids-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD4_c06-NR4A2\|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)	TCEA3 DNAJB1 INPP4B NOSIP FYB1	5.63e-05	180	101	5	f3d35b2ea78afef37a84232adf5e6e26712b618d
ToppCell	PND10-Immune-Immune_Lymphocytic_T/NK-Lymphocytic_T\|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	SH3KBP1 LCP2 INPP4B ELF1 FYB1	5.78e-05	181	101	5	61c6e000db7047fda4b4bb5024f3af24577e7d29
ToppCell	Epithelial-lung_neuroendocrine_cell_(PNEC)\|World / Lineage, Cell type, age group and donor	CACNA1B PCLO BSN ST18 CDK5R2	5.93e-05	182	101	5	57bf4ffb304324e2e392e196336a530d9f78fe0d
ToppCell	AT1-AT2_cells-Donor_02\|World / lung cells shred on cell class, cell subclass, sample id	PCLO CCDC85A FARP1 DIAPH3 ARHGEF26	6.09e-05	183	101	5	6821dca076318115d360ff426eb1218cfe104063
ToppCell	nucseq-Epithelial-Epithelial_Alveolar-AT1-AT1\|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	MAGI1 CCDC85A FARP1 DIAPH3 ARHGEF26	6.25e-05	184	101	5	57c792e6e2fedba25d3350ffe649fd74750b579d
ToppCell	Adult-Epithelial-alveolar_epithelial_cell_type_1-D122\|Adult / Lineage, Cell type, age group and donor	MAGI1 CCDC85A FARP1 DIAPH3 ARHGEF26	6.25e-05	184	101	5	561592edc3083fad41b91811151b442207c65dd9
ToppCell	nucseq-Epithelial-Epithelial_Alveolar-AT1\|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	MAGI1 CCDC85A FARP1 DIAPH3 ARHGEF26	6.25e-05	184	101	5	d7bd0f0c607bade67c99e9fb3578a570298bf926
ToppCell	droplet-Lung-LUNG-30m-Myeloid-Proliferating_Alveolar_Macrophage\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	NSD2 PCLO CKAP5 RAD54B DIAPH3	6.25e-05	184	101	5	16aa8e88bdd51b1d132d5cf33c29963b384a8bae
ToppCell	Children_(3_yrs)-Epithelial-alveolar_epithelial_cell_type_1\|Children_(3_yrs) / Lineage, Cell type, age group and donor	MAGI1 CCDC85A FARP1 DIAPH3 ARHGEF26	6.41e-05	185	101	5	1c222f7285d6e3dae0354dc7e853ddc0ea55e63e
ToppCell	Smart-seq2-spleen_(Smart-seq2)-lymphocytic-T_lymphocytic-naive_thymus-derived_CD4-positive,_alpha-beta_T_cell\|spleen_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type	TCEA3 DNAJB1 INPP4B NOSIP FYB1	6.41e-05	185	101	5	608c16c0ff251926e3e62a6cb66f835163302538
ToppCell	343B-Lymphocytic-CD4_T-cell\|343B / Donor, Lineage, Cell class and subclass (all cells)	DNAJB1 NACA INPP4B NOSIP FYB1	6.57e-05	186	101	5	f6743d1f1d57d9d9a4581a88f156078a1da46816
ToppCell	Immune-enucleated_erythrocyte\|World / Lineage, Cell type, age group and donor	DNAJB1 E2F2 SLC16A1 TMCC2 MICAL3	6.57e-05	186	101	5	f9d5ec5cc8fd6e63bf25abe390307ec8a4a2d5a3
ToppCell	Epithelial-alveolar_epithelial_cell_type_1\|World / Lineage, Cell type, age group and donor	MAGI1 CCDC85A FARP1 DIAPH3 ARHGEF26	6.57e-05	186	101	5	09d95daa3387a4814cffaa4b798cc2810c3759d0
ToppCell	Substantia_nigra-Neuronal\|Substantia_nigra / BrainAtlas - Mouse McCarroll V32	CACNA1B PCLO GRM1 BSN CDK5R2	6.57e-05	186	101	5	3f889083fcffe516388e9b03a5e23af2010ced33
ToppCell	Fetal_29-31_weeks-Epithelial-lung_neuroendocrine_cell_(PNEC)\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	CACNA1B PCLO BSN ST18 CDK5R2	6.57e-05	186	101	5	b45cce768e4bf91da194fd9660cab7520dfb15ac
ToppCell	PBMC_fresh-frozen-Severe-critical_progression_d12-22_no-steroids-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD4_c07-AHNAK\|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)	TCEA3 DNAJB1 INPP4B NOSIP FYB1	6.74e-05	187	101	5	e1d6c1194476cf26969e405b0951796fed519f44
ToppCell	Children_(3_yrs)-Epithelial-alveolar_epithelial_cell_type_1-D139\|Children_(3_yrs) / Lineage, Cell type, age group and donor	MAGI1 CCDC85A FARP1 DIAPH3 ARHGEF26	6.74e-05	187	101	5	d4b0afd9b92c47c8aa348bbd1af7eb54c3d478f2
ToppCell	Adult-Epithelial-alveolar_epithelial_cell_type_1\|Adult / Lineage, Cell type, age group and donor	MAGI1 CCDC85A FARP1 DIAPH3 ARHGEF26	6.74e-05	187	101	5	77f78aec946bc6bd85c29aee9ca978ce49f853a3
ToppCell	LPS-IL1RA-Stromal_mesenchymal-Lung_smooth_muscle-Myofibroblast\|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	TCEA3 SFRP4 AEBP1 LMOD1 CDH4	6.91e-05	188	101	5	3177b2c1723268d330d3e9f24f9e24492ace6286
ToppCell	PBMC_fresh-frozen-Severe-critical_progression_d12-22_with-steroid-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD4_c06-NR4A2\|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)	DNAJB1 INPP4B NOSIP CACNA1I FYB1	6.91e-05	188	101	5	939790f133eac9c12d08db6ddb5f08f5107844e3
ToppCell	Fetal_29-31_weeks-Epithelial-lung_neuroendocrine_cell_(PNEC)-D150\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	CACNA1B PCLO BSN ST18 CDK5R2	6.91e-05	188	101	5	c4c3b21ab723b0e9beff9ec84f8d68485f771528
ToppCell	Smart-seq2-tissue-resident_(Smart-seq2)-lymphocytic-T_lymphocytic-CD4-positive_helper_T_cell\|tissue-resident_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type	TCEA3 INPP4B NOSIP CACNA1I FYB1	6.91e-05	188	101	5	f7dd01084ad14d2a2d8adf552e811b84eebf5514
ToppCell	renal_papilla_nuclei-Hypertensive_with+without-CKD-Immune-Myeloid\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	SH3KBP1 LCP2 FMN1 PLEKHO1 ST18	7.09e-05	189	101	5	7ccea2df93bb4b37417bbc8f6c85a61ece95211a
ToppCell	PBMC_fresh-frozen-Severe-critical_progression_d12-22_no-steroids-Lymphocytic-Lymphocytic_T\|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)	TCEA3 DNAJB1 INPP4B NOSIP FYB1	7.09e-05	189	101	5	5a9e2ca9a9ee2dc37ab9147a902115a9f1a80169
ToppCell	Control-Endothelial-Endothelial-FOXM1\|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	NSD2 CKAP5 E2F2 IQCD DIAPH3	7.09e-05	189	101	5	1e1499b062d9c647c8f38b0c4e0d871d159be5dd
ToppCell	RV-15._Ventricular_Cardiomyocyte_III\|World / Chamber and Cluster_Paper	MAGI1 OBSCN FNDC3A ALPK3 MICAL3	7.09e-05	189	101	5	0a82931b5f6c0a6427ca3edd5e2235ac49099d40
ToppCell	Adult-Epithelial-alveolar_epithelial_cell_type_1-D231\|Adult / Lineage, Cell type, age group and donor	MAGI1 CCDC85A FARP1 DIAPH3 ARHGEF26	7.09e-05	189	101	5	5a04cb25f8f0447b2cecdb6c3695029281aca26d
ToppCell	RV-15._Ventricular_Cardiomyocyte_III\|RV / Chamber and Cluster_Paper	MAGI1 OBSCN FNDC3A ALPK3 MICAL3	7.27e-05	190	101	5	93c3188dfeb0b2f9889f8ae9b9c1f2f34129c99b
ToppCell	Globus_pallidus-Neuronal\|Globus_pallidus / BrainAtlas - Mouse McCarroll V32	CACNA1B TSPOAP1 KMT2A BSN CDK5R2	7.27e-05	190	101	5	416de85d8841dac883faa6f5339b2fb461a09e82
ToppCell	Children_(3_yrs)-Epithelial-alveolar_epithelial_cell_type_1-D032\|Children_(3_yrs) / Lineage, Cell type, age group and donor	MAGI1 CCDC85A FARP1 DIAPH3 ARHGEF26	7.27e-05	190	101	5	30b50d183d7649146eb1e79b47ba897355f1998a
ToppCell	normal_Lymph_Node-B_lymphocytes-Undetermined\|B_lymphocytes / Location, Cell class and cell subclass	DNAJB1 LCP2 INPP4B NOSIP FYB1	7.27e-05	190	101	5	85cf147f2baf2e575073b4edab57c7809475268a
ToppCell	PBMC_fresh-frozen-Mild-Moderate_progression_d02_child-Lymphocytic-Lymphocytic_T\|Mild-Moderate_progression_d02_child / Compartment, severity and other cell annotations on 10x 3' data (130k)	DNAJB1 LCP2 INPP4B FMN1 FYB1	7.45e-05	191	101	5	9bb6a6b88f351217455765ba07a6acf11fda98f4
ToppCell	renal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Immune-Myeloid-Macrophage_Dendritic\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	SH3KBP1 LCP2 FMN1 FYB1 PLEKHO1	7.45e-05	191	101	5	51f5af610983aa73b9f4ece6f27d281ebff89a04
ToppCell	Adult-Immune-monocyte-D175\|Adult / Lineage, Cell type, age group and donor	VASH1 LCP2 FYB1 PLEKHO1 ST18	7.45e-05	191	101	5	cbebb4d9550fdcd606cb3685ac9546c6b73fd422
ToppCell	renal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Immune-Myeloid-Macrophage_Dendritic-M2_Macrophage\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	SH3KBP1 LCP2 FMN1 FYB1 PLEKHO1	7.45e-05	191	101	5	8fd6bdc9d2b1c8d364221d7bc68d03921b668ab5
ToppCell	10x5'v1-week_17-19-Endothelial-stroma-proliferating_EC\|week_17-19 / cell types per 3 fetal stages;per 3',per 5'	MAGI1 ALPK3 TNKS1BP1 BSN CDH4	7.45e-05	191	101	5	dc9e5eb6aa31b8d79aeec33e59b9138dfb469a3b
ToppCell	T_cells-Central_memory_CD4+_T_cells\|T_cells / Immune cells in Kidney/Urine in Lupus Nephritis	TCEA3 INPP4B NOSIP FMN1 CACNA1I	7.45e-05	191	101	5	25dd538d6a361bd3367c8a1c0dfc9e7003061af3
ToppCell	343B-Lymphocytic-CD4_T-cell\|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)	DNAJB1 NACA INPP4B NOSIP FYB1	7.64e-05	192	101	5	016a8cb8f7e74cba7270e3d1aa91589083663216
ToppCell	PBMC_fresh-frozen-Mild-Moderate_progression_d02_child-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell\|Mild-Moderate_progression_d02_child / Compartment, severity and other cell annotations on 10x 3' data (130k)	DNAJB1 LCP2 INPP4B FMN1 FYB1	7.64e-05	192	101	5	1c0ce299cee9ab5cdea256f3e8c1e5598577a8b6
ToppCell	droplet-Spleen-SPLEEN-1m-Hematologic-megakaryocyte-erythroid_progenitor_cell\|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	VASH1 HMGB3 IQCD GSTA4 BSN	7.64e-05	192	101	5	a94f47a664a3c9d1b0250269674453309ab4bf95
ToppCell	PBMC_fresh-frozen-Severe-critical_convalescent_d42-56-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD4_c05-FOS\|Severe-critical_convalescent_d42-56 / Compartment, severity and other cell annotations on 10x 3' data (130k)	TCEA3 INPP4B NOSIP FMN1 CACNA1I	7.64e-05	192	101	5	78546a6e077076834fd717607610ab6df3b6e7ba
ToppCell	Fetal_29-31_weeks-Immune-monocyte-D150\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	VASH1 ZNF217 FYB1 PLEKHO1 ST18	7.64e-05	192	101	5	5417f024fcc89eaeab33f4a2c6421d1cfabd681b
ToppCell	Entopeduncular-Neuronal\|Entopeduncular / BrainAtlas - Mouse McCarroll V32	CACNA1B GRM1 CACNA1I BSN CDK5R2	7.64e-05	192	101	5	4c35e5c28a40b439044797ba1f06cb7c36b2a8de
ToppCell	renal_cortex_nuclei\|World / Celltypes from Cells and Nuclei per compartment and clinical group	MAGI1 STAG1 SCMH1 FARP1 SETBP1	7.64e-05	192	101	5	e8cc4d08fcfceeab75a02558817e4ccd7dbafe3a
ToppCell	facs-Brain_Non-Myeloid-Cortex-24m-Neuronal\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TSPOAP1 PCLO GRM1 CRACDL BSN	7.82e-05	193	101	5	be28070c049e7cb68bcd54f582226eb2f5e4bc1c
ToppCell	mild_COVID-19-CD4+_T_naive\|mild_COVID-19 / disease group, cell group and cell class (v2)	TCEA3 DNAJB1 INPP4B NOSIP FYB1	7.82e-05	193	101	5	40fc4a519c883c6c269a9c05be36ae906f75426a
ToppCell	(1)_T_cells-(1)_T_CD4\|(1)_T_cells / Lung cell shreds - cell class (v4) and cell subclass (v4)	DNAJB1 INPP4B NOSIP ELF1 FYB1	7.82e-05	193	101	5	788daf1d7c7a26eb052b386a114248772e05c27e
ToppCell	T_cells-Central_memory_CD4+_T_cells\|World / Immune cells in Kidney/Urine in Lupus Nephritis	INPP4B NOSIP FMN1 CACNA1I FYB1	7.82e-05	193	101	5	725326d7e3604736b607c19f4069c81cb4f2d20c
ToppCell	10x_3'_v3-tissue-resident_(10x_3'_v3)-lymphocytic-T_lymphocytic-CD4-positive_helper_T_cell\|tissue-resident_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type	TCEA3 INPP4B NOSIP CACNA1I FYB1	7.82e-05	193	101	5	792315f409a57fa6a8a88c850060b1e089e062ea
ToppCell	distal-Hematologic-IGSF21+_Dendritic-1\|distal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	FMN1 ZFHX3 CACNA1I FYB1 PLEKHO1	7.82e-05	193	101	5	48ce11778252ae2ef902b30816061b59a3c81695
ToppCell	facs-Brain_Non-Myeloid-Cortex-24m-Neuronal-nan\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TSPOAP1 PCLO GRM1 CRACDL BSN	7.82e-05	193	101	5	0c652ebe22ce5d2927599dd97ef1920547858395
ToppCell	facs-Brain_Non-Myeloid-Cortex-24m-Neuronal-neuron\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TSPOAP1 PCLO GRM1 CRACDL BSN	7.82e-05	193	101	5	8689a70a33a7c3823dc647d41ac0160e7c3ae396
ToppCell	3'_v3-lymph-node_spleen-Lymphocytic_T_CD4-Tfh\|lymph-node_spleen / Manually curated celltypes from each tissue	DNAJB1 INPP4B ELF1 CACNA1I FYB1	7.82e-05	193	101	5	dea7d0b2eadff01e0e169c6916dea04253521d48
ToppCell	356C-Lymphocytic-CD4_T-cell\|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)	DNAJB1 NACA INPP4B NOSIP FYB1	8.02e-05	194	101	5	f51760caee571307851c78897789f6e43bac44ae
ToppCell	distal-1-Hematologic-IGSF21+_Dendritic\|1 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	FMN1 ZFHX3 CACNA1I FYB1 PLEKHO1	8.02e-05	194	101	5	f30c866e5f41ee79bdc6b6e08af962d62b199835
ToppCell	356C-Lymphocytic-CD4_T-cell-CD4+_Naive_T_cell_/_CD4+_Trm_cell\|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)	DNAJB1 NACA INPP4B NOSIP FYB1	8.02e-05	194	101	5	01eab9f799a0bf4af1f2bffedaa1d926d98abe0f
ToppCell	PBMC_fresh-frozen-Severe-critical_progression_d12-22_with-steroid-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD4_c01-LEF1\|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)	TCEA3 INPP4B NOSIP CACNA1I FYB1	8.02e-05	194	101	5	a7bfc535546d3c1a4e0cbcfeb7da816b34303350
ToppCell	10x_3'_v3-lymph_node_(10x_3'_v3)-lymphocytic-T_lymphocytic-effector_CD4-positive,_alpha-beta_T_cell\|lymph_node_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type	DNAJB1 NACA INPP4B NOSIP FYB1	8.21e-05	195	101	5	e4caa01d2040a6f4dd90e68c2e1e99c5405e2eba
ToppCell	PBMC_fresh-frozen-Mild-Moderate_convalescent_d36-51-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell\|Mild-Moderate_convalescent_d36-51 / Compartment, severity and other cell annotations on 10x 3' data (130k)	TCEA3 INPP4B NOSIP FMN1 FYB1	8.21e-05	195	101	5	497d4bfbc38bcafab37e8a9c20bc9141f2e78d2a
Drug	3,4-dihydroquinazoline	CACNA1B CACNA1I CACNA1G	1.63e-06	6	100	3	CID000583065
Disease	alcohol consumption measurement	MAGI1 PCLO BRD3 INPP4B WDR43 NOSIP ZZZ3 FARP1 SETBP1 ZFHX3 CACNA1I MICAL3 ST18 CDH4 AFF4	9.92e-06	1242	95	15	EFO_0007878
Disease	oppositional defiant disorder measurement	MYLK2 MLLT1 ST18	2.14e-04	36	95	3	EFO_0007679
Disease	intraocular pressure measurement	STAG1 PCLO CKAP5 BRD3 ZNF469 KMT2A ZFHX3 DLEC1	2.43e-04	509	95	8	EFO_0004695
Disease	neutrophil measurement	TSPOAP1 E2F2 RRBP1 TMCC2 ELF1	2.75e-04	177	95	5	EFO_0803548
Disease	creatinine measurement	TCEA3 STAG1 OBSCN RGS14 ZZZ3 SCMH1 SETBP1 ZFHX3 DLEC1 BSN ARHGEF26	3.58e-04	995	95	11	EFO_0004518
Disease	apolipoprotein A 1 measurement	TCEA3 CYP2A6 STAG1 FNDC3A BRD3 RRBP1 KMT2A TNKS1BP1 DLEC1 PLEKHO1	4.07e-04	848	95	10	EFO_0004614
Disease	Dupuytren Contracture	SFRP4 ATE1 MROH1 TMCC2	4.18e-04	108	95	4	EFO_0004229
Disease	C-reactive protein measurement	CYP2A6 CAST BRD3 ZNF469 TMCC2 TNKS1BP1 MICAL3 BSN FYB1 BCL2L13 CDH4 AFF4	4.93e-04	1206	95	12	EFO_0004458
Disease	primary angle closure glaucoma	SFRP4 ST18	5.54e-04	11	95	2	EFO_1001506
Disease	L2 Acute Lymphoblastic Leukemia	ABL1 NSD2 KMT2A	5.68e-04	50	95	3	C0023453
Disease	Childhood Acute Lymphoblastic Leukemia	ABL1 NSD2 KMT2A	6.37e-04	52	95	3	C0023452
Disease	aspartate aminotransferase measurement	MAGI1 CYP2A6 CAST OBSCN BRD3 ZC3H18 RRBP1 INPP4B TMCC2 ELF1	6.68e-04	904	95	10	EFO_0004736
Disease	age at menarche	CAST FNDC3A ATE1 CCDC85A SCMH1 BSN ST18 KDM4B	6.74e-04	594	95	8	EFO_0004703
Disease	frontotemporal dementia, age at onset	RRBP1 ST18	7.82e-04	13	95	2	EFO_0004847, MONDO_0017276
Disease	Hypertrophic Cardiomyopathy	OBSCN MYLK2 ALPK3	8.34e-04	57	95	3	C0007194
Disease	schizophrenia, intelligence, self reported educational attainment	STAG1 BRD3 FARP1 KMT2A CACNA1I PLEKHO1	9.01e-04	346	95	6	EFO_0004337, EFO_0004784, MONDO_0005090
Disease	Precursor Cell Lymphoblastic Leukemia Lymphoma	ABL1 NSD2 KMT2A	1.02e-03	61	95	3	C1961102
Disease	MAJOR AFFECTIVE DISORDER 2	MAGI1 TOM1	1.35e-03	17	95	2	C1839839
Disease	lysophosphatidylcholine 18:1 measurement	CCDC85A ST18	1.35e-03	17	95	2	EFO_0010360
Disease	non-Hodgkin lymphoma (is_implicated_in)	RAD54B KMT2A	1.35e-03	17	95	2	DOID:0060060 (is_implicated_in)
Disease	Multiple congenital anomalies	SETBP1 AFF4	1.35e-03	17	95	2	C0000772
Disease	nasopharyngeal neoplasm	CYP2A6 PCLO KMT2A ZFHX3	1.46e-03	151	95	4	EFO_0004252
Disease	Myeloid Leukemia	SETBP1 KMT2A	1.52e-03	18	95	2	C0023470
Disease	Leukemia, Monocytic, Chronic	SETBP1 KMT2A	1.52e-03	18	95	2	C0023466
Disease	CCL4 measurement	TBC1D3 TBC1D3F	1.88e-03	20	95	2	EFO_0004751
Disease	base metabolic rate measurement	GDF5 MICAL3	1.88e-03	20	95	2	EFO_0007777
Disease	Colorectal Carcinoma	CYP2A6 SFRP4 OBSCN ZNF217 GRM1 AMER2 ZZZ3 SETBP1	1.95e-03	702	95	8	C0009402
Disease	Precursor B-cell lymphoblastic leukemia	ABL1 KMT2A	2.07e-03	21	95	2	C1292769
Disease	hemoglobin change measurement	MAGI1 KMT2A	2.27e-03	22	95	2	EFO_0600027
Disease	cotinine measurement	CYP2A6 CDH4	2.48e-03	23	95	2	EFO_0007813
Disease	sensory peripheral neuropathy, remission	KMT2A DLEC1	2.48e-03	23	95	2	EFO_0009785, MONDO_0002321
Disease	acute myeloid leukemia (is_implicated_in)	ABL1 KMT2A DLEC1	2.55e-03	84	95	3	DOID:9119 (is_implicated_in)
Disease	QRS duration	TCEA3 NACA SETBP1 KMT2A DLEC1	2.81e-03	298	95	5	EFO_0005055
Disease	erosive tooth wear measurement	DLEC1 DIAPH3 CDH4	3.10e-03	90	95	3	EFO_0009331
Disease	cortical thickness	MAGI1 NHSL1 ZNF469 KMT2A MICAL3 TMEM131 DLEC1 DIAPH3 ST18 KDM4B	3.11e-03	1113	95	10	EFO_0004840
Disease	visuospatial function measurement	INPP4B FARP1	3.17e-03	26	95	2	EFO_0803533
Disease	myeloperoxidase measurement	TSPOAP1 RRBP1	3.17e-03	26	95	2	EFO_0005243

Protein segments in the cluster

Peptide	Gene	Start	Entry
SPASEKKPVPPSEGK	BCL2L13	426	Q9BXK5
KKPVPPSEGKSRLSP	BCL2L13	431	Q9BXK5
ELLPPAPKGKGRKPA	BRD3	146	Q15059
PGPGKPALSKKNPGV	AMER2	401	Q8N7J2
KGRKTKPPRPDSPAT	ELF1	176	P32519
RPKGKPCPKEIPKES	ERVK-19	221	O71037
RPKGKPCPKEIPKES	ERVK-8	221	Q902F8
QRKSKGKLPPGPTPL	CYP2A6	26	P11509
PKESLEGSPRPPKKG	AEBP1	106	Q8IUX7
EGSPRPPKKGKEKPP	AEBP1	111	Q8IUX7
GPKTDPSKRPADPLK	IQCD	21	Q96DY2
APPKPKGEATTDSKP	ALPK3	686	Q96L96
PLPAESPKKGPKKVA	BAP18	91	Q8IXM2
PKSPKLPKAVPGGSP	ARHGEF26	111	Q96DR7
PGSKKERPPLPNLKT	DIAPH3	81	Q9NSV4
DRFGGREPPKPKPSL	CACNA1B	2131	Q00975
KVPGEGLPLPKTPEK	DNAJB1	296	P25685
KKVTPKPASTGPDPL	CDK5R2	81	Q13319
FSGKPPEKPLPNGKG	FAM90A10	121	A6NDY2
IPGKPYKETEPPKGE	AFF4	726	Q9UHB7
KKPKFIPPGRSNPGL	RAD54B	16	Q9Y620
GPPPKPRRSKKAESE	TSPOAP1	1731	O95153
DSSQPRGDKKKPSPP	FMN1	481	Q68DA7
RGDKKKPSPPAPAAL	FMN1	486	Q68DA7
FSGKPPEKPLPNGKG	FAM90A7	121	A6NKC0
PSVGPPSKDKDKVLP	NOSIP	146	Q9Y314
FSGKPPEKPLPNGKG	FAM90A23	121	A8MXZ1
RPIGPKPTKAGKDKS	SLC16A1	196	P53985
GGLPKEPAKPKEPTI	MMP27	261	Q9H306
GEARKPAKPPVSPKP	CASKIN1	1216	Q8WXD9
EKKSKGEGRPPEKPS	MICAL3	1711	Q7RTP6
KDEPKKLPPRPGGPE	GDF5	91	P43026
PPPKPGAATEKARKQ	H1-8	186	Q8IZA3
RGGLPVPKKSPKSQP	MAGI1	721	Q96QZ7
RPKSPPPKSKSDRGG	METTL14	396	Q9HCE5
ARPGGILKKPPSPKS	INPP4B	476	O15327
TPGPLGRFEKKKPDP	BSN	2751	Q9UPA5
FSGKPPEKPLPNGKG	FAM90A22	121	A8MWA6
VSPANGKGKPKPKVP	NHSL1	876	Q5SYE7
FSGKPPEKPLPNGKG	FAM90A14	121	P0C7W9
PPKDKKRPTPLEIGY	PCLO	3586	Q9Y6V0
SPKPSPKNSPKKGGA	LMOD1	516	P29536
AAGKDPGPPDPKKAP	MYLK2	31	Q9H1R3
TKTEKPPPEPGKPKG	NSD2	1336	O96028
KEPKPPFLKPTGAGQ	FYB1	76	O15117
KKPKPEDPKFPGEGT	KDM4B	381	O94953
KKAPEPPKTDKPGAA	MED12	1761	Q93074
FSGKPPEKPLPNGKG	FAM90A17	121	P0DV74
EPEKPGPGSKDPKAD	MROH1	446	Q8NDA8
FSGKPPEKPLPNGKG	FAM90A16	121	P0DV73
LKSPKGSGKPPGVPA	NKD2	331	Q969F2
RPKGKPCPKEIPKES	ERVK-7	981	P63135
GKGKARPPEPLSSKP	CRACDL	746	Q6NV74
FSGKPPEKPLPNGKG	FAM90A19	121	P0DV76
GKKEKPPFLPEEPSS	RBBP6	231	Q7Z6E9
LEKEGPPRKKPGLAS	OBSCN	7436	Q5VST9
FSGKPPEKPLPNGKG	FAM90A8	121	A6NJQ4
RFLEPGSKKKPPPDE	GSTA4	196	O15217
SAPKPGPLKKAPAAK	CKAP5	536	Q14008
RVDGLPSPKTPKSPG	E2F2	111	Q14209
PGGQEEPPSPRDLKK	CACNA1G	2231	O43497
GGPGSRPKKKLSPPS	CACNA1G	2296	O43497
RPKGKPCPKEIPKES	ERVK-25	221	P61570
RPKGKPCPKEIPKES	ERVK-6	221	Q69384
EPKPKPKPVLFSRGS	FARP1	321	Q9Y4F1
PKPAVTPGPGSLKGK	GAS2L2	681	Q8NHY3
PDKPGIPVKPSVKGK	FNDC3A	561	Q9Y2H6
PPGRKDSKGELDPPE	CACNA1I	1881	Q9P0X4
TTGKKPAPKGQAPLP	CC2D1B	61	Q5T0F9
GKKVVALDPSPPPKD	CDH4	136	P55283
PAIKKPPSGFKGTIP	DIDO1	581	Q9BTC0
PGEGLKKPVLPATPK	ABL1	951	P00519
GTPDRPKALKGPSPE	CCDC85A	266	Q96PX6
PAVPVESKPDKPSGK	CAST	136	P20810
VPKPGKGADLSKPPC	ATE1	191	O95260
KKKDPNAPKRPPSGF	HMGB3	86	O15347
KKIIPAPKPKGPGEP	KMT2A	1821	Q03164
RPKGKPCPKEIPKES	HERVK_113	221	Q902F9
GRLPKEEKAPPPKAA	MLLT1	236	Q03111
FSGKPPEKPLPNGKG	FAM90A20P	121	A6NIJ5
LPDGQSLPPGRTKKP	GRM1	141	Q13255
GKSLVFPPKKPAPIG	DLEC1	341	Q9Y238
FSGKPPEKPLPNGKG	FAM90A5P	121	A8MXJ8
FSGKPPEKPLPNGKG	FAM90A24P	121	P0C7X0
QEPPKDGKPKDPRKP	FER1L6	1176	Q2WGJ9
APNPGPRSKPPDLKK	TMCC2	56	O75069
FSGKPPEKPLPNGKG	FAM90A12P	121	A8MX19
FSGKPPEKPLPNGKG	FAM90A9	121	A6NNJ1
FSGKPPEKPLPNGKG	FAM90A13P	121	P0C7W8
FSGKPPEKPLPNRKG	FAM90A26	121	D6RGX4
EKEGNRPKKPPPPSA	SH3KBP1	331	Q96B97
KSKRDSGEGPGKKPP	PPP1R26	756	Q5T8A7
APKTNKSPEAKPLPG	NOP2	61	P46087
KSPEAKPLPGKLPKG	NOP2	66	P46087
DGKRKAKDPPRSPPD	PLEKHO1	331	Q53GL0
FSGKPPEKPLPNGKG	FAM90A15P	121	P0C7V4
KPAPKELAPTTTKGP	PRG4	796	Q92954
EPLKFPKKRGPKPGS	SCMH1	301	Q96GD3
EKKFPGEASIPSPKP	ST18	696	O60284
APPPPGAKPEEDKKD	CMTM2	16	Q8TAZ6
SKKKGEPGPPDADGP	RRBP1	631	Q9P2E9
TRKKGDVPPPAKPEQ	TBC1D3F	351	A6NER0
PPSGPAPRKKTQEKD	TOM1	471	O60784
GRTSRSNPPKPKGKP	SFRP4	306	Q6FHJ7
GIKKGPPRKLKFPEP	SELENOH	96	Q8IZQ5
GKPLTLPPKPEKSSG	TNKS1BP1	1696	Q9C0C2
EQPPSPLPKSKGKGK	TMEM131	1371	Q92545
RPKGKPCPKEIPKES	ERVK-10	981	P10266
PAPGPSPADKKRSGK	WAS	216	P42768
GRPPSTNKKPRKSPG	STAG1	41	Q8WVM7
KRLLDSPGPPKGEKG	TCEA3	76	O75764
TRKKGDLPPPAKPEQ	TBC1D3E	351	A0A087X179
PKLKPGKSLPLGVEE	RGS14	211	O43566
KSKAGVTPESKAPPP	ZNF469	886	Q96JG9
SLPAPGSRPKKPLGK	TIRAP	6	P58753
KGKQSPPGPGKAPLT	ZNF217	791	O75362
GGKPPTPPPKILSEK	PLEKHO2	306	Q8TD55
GKGTGPPSPTKDRKK	VASH1	306	Q7L8A9
GTKEPPEPPTVGSKK	SETBP1	321	Q9Y6X0
TRKKGDLPPPAKPEQ	TBC1D3	351	Q8IZP1
PARPKSPLDPKKDGE	ZZZ3	601	Q8IYH5
TRKKGDLPPPAKPEQ	TBC1D3K	351	A0A087X1G2
TRKKGDLPPPAKPEQ	TBC1D3C	351	Q6IPX1
TKGEPAPPPGKAGEK	ZC3H18	621	Q86VM9
APPPGKAGEKSVKKP	ZC3H18	626	Q86VM9
KAGEKSVKKPAPPPA	ZC3H18	631	Q86VM9
KRKKRPPPSTAGEPG	ZNF541	951	Q9H0D2
TPGKGKKSTPKPIPI	WDR43	321	Q15061
GEPLPVPKKEKGEAP	ZFHX3	3251	Q15911
FSGKPPEKPLPNGKG	FAM90A18	121	P0DV75
TLGKKPPFSDKPSIP	LCP2	256	Q13094
AKKSLGEPLPIGKPA	NACA	591	E9PAV3
KRPPTKKGSAGPDTP	NACA	806	E9PAV3