Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyBiologicalProcess	striated muscle cell differentiation	BHLHE41 NEURL2 PDGFRB ADGRB1 OBSCN NIBAN2 FKTN MTOR EHD1 PLEC MMP14 TNNT3	1.12e-05	391	136	12	GO:0051146
GeneOntologyBiologicalProcess	myotube differentiation	BHLHE41 ADGRB1 NIBAN2 FKTN MTOR EHD1 PLEC MMP14	1.34e-05	164	136	8	GO:0014902
GeneOntologyCellularComponent	anchoring junction	NEURL2 DSC2 PDGFRB ANXA1 CAPN1 ADGRB1 OBSCN NIBAN2 AKAP12 LIN7A HMCN1 AHNAK SYNE2 TJP2 KIFC3 PLEC ATP1A1 PATJ MMP14 TJP3	8.10e-06	976	140	20	GO:0070161
GeneOntologyCellularComponent	motile cilium	DNHD1 DNAH3 ANXA1 CFAP36 IFT172 PRAMEF2 LDHA AKAP9 ATP1A1 SLC26A6	1.43e-04	355	140	10	GO:0031514
GeneOntologyCellularComponent	cell-cell junction	DSC2 ANXA1 ADGRB1 OBSCN NIBAN2 LIN7A HMCN1 AHNAK TJP2 KIFC3 ATP1A1 PATJ TJP3	1.75e-04	591	140	13	GO:0005911
GeneOntologyCellularComponent	cell-substrate junction	NEURL2 PDGFRB ANXA1 CAPN1 ADGRB1 AKAP12 HMCN1 AHNAK SYNE2 PLEC MMP14	2.00e-04	443	140	11	GO:0030055
GeneOntologyCellularComponent	cilium	DNHD1 DNAH3 ANXA1 CFAP36 IFT172 PRAMEF2 LDHA IFT43 AKAP9 EHD1 ATP1A1 CPLANE1 KIF17 SLC26A6 TTLL13 INVS	3.45e-04	898	140	16	GO:0005929
GeneOntologyCellularComponent	cell-cell contact zone	DSC2 OBSCN AHNAK TJP2 ATP1A1	4.27e-04	94	140	5	GO:0044291
GeneOntologyCellularComponent	adherens junction	DSC2 ANXA1 NIBAN2 LIN7A HMCN1 TJP2 KIFC3	5.75e-04	212	140	7	GO:0005912
GeneOntologyCellularComponent	procentriole replication complex	SASS6 CEP152	6.56e-04	6	140	2	GO:0120099
GeneOntologyCellularComponent	deuterosome	SASS6 CEP152	6.56e-04	6	140	2	GO:0098536
GeneOntologyCellularComponent	muscle tendon junction	NEURL2 HMCN1	6.56e-04	6	140	2	GO:0005927
GeneOntologyCellularComponent	9+2 motile cilium	DNHD1 DNAH3 IFT172 LDHA AKAP9 ATP1A1 SLC26A6	1.13e-03	238	140	7	GO:0097729
GeneOntologyCellularComponent	cornified envelope	DSC2 ANXA1 CAPN1 FLG2	1.19e-03	69	140	4	GO:0001533
GeneOntologyCellularComponent	postsynaptic membrane	ERBB3 TRPV1 ADGRB1 SHC4 GPR179 CHRND LIN7A AKAP9 GRIP2	1.66e-03	405	140	9	GO:0045211
GeneOntologyCellularComponent	sarcolemma	ANXA1 OBSCN AHNAK PLEC ATP1A1 VDR	1.79e-03	190	140	6	GO:0042383
GeneOntologyCellularComponent	inner dynein arm	DNHD1 DNAH3	1.93e-03	10	140	2	GO:0036156
MousePheno	abnormal blood circulation	RNASEH2B ERBB3 TRPV1 ABCA3 PLOD3 PDGFRB GLRX3 IFT172 APAF1 LAMA4 CHD2 SMG5 AKAP12 JARID2 MECR CHRD FNIP1 PLCG2 PLEC TNNT3 MMUT INVS	9.06e-07	845	113	22	MP:0002128
MousePheno	hemorrhage	RNASEH2B ABCA3 PLOD3 PDGFRB GLRX3 IFT172 APAF1 LAMA4 CHD2 SMG5 JARID2 MECR CHRD PLCG2 PLEC TNNT3 MMUT INVS	5.89e-06	664	113	18	MP:0001914
MousePheno	abnormal basement membrane morphology	PLOD3 PDGFRB LAMA4 FKTN MMP14	1.66e-05	40	113	5	MP:0004272
MousePheno	abnormal renal glomerulus morphology	TRPV1 PDGFRB IFT172 RTN3 XDH CHD2 BHLHE40 PLCG2 MMP14 INVS	5.48e-05	264	113	10	MP:0005325
MousePheno	abnormal embryo development	RNASEH2B PLOD3 GLRX3 IFT172 MTERF3 NOC3L CHD1 UPF1 IFT43 CHRND NCOR2 POGLUT1 MECR FBXO5 HMCN1 FKTN MTOR CHRD TJP2 SASS6 KDM8 CPLANE1 SLC33A1 EIF3M INVS	7.73e-05	1370	113	25	MP:0001672
MousePheno	impaired basement membrane formation	PLOD3 LAMA4 FKTN	8.10e-05	11	113	3	MP:0003044
MousePheno	increased heart ventricle size	DSC2 PDGFRB IFT172 LAMA4 CHRD FNIP1 ATP1A1 VDR	8.61e-05	175	113	8	MP:0008772
MousePheno	abnormal renal corpuscle morphology	TRPV1 PDGFRB IFT172 RTN3 XDH CHD2 BHLHE40 PLCG2 MMP14 INVS	1.30e-04	293	113	10	MP:0002827
Domain	DUF4208	CHD1 CHD2	1.62e-04	3	138	2	PF13907
Domain	DUF4208	CHD1 CHD2	1.62e-04	3	138	2	IPR025260
Domain	ZO	TJP2 TJP3	1.62e-04	3	138	2	IPR005417
Domain	DUF4208	CHD1 CHD2	1.62e-04	3	138	2	SM01176
Pubmed	Proteome-wide identification of HSP70/HSC70 chaperone clients in human cells.	HNRNPDL ANXA1 CFAP36 CAPN1 SQLE NOC3L PSMD12 NIBAN2 UPF1 RFC2 LDHA AKAP12 NCOR2 PDE12 SPATS2L COMMD8 MTOR AHNAK SYNE2 AHCY TJP2 GSDMA ATP1A1 EIF3M MMUT	2.27e-10	1367	140	25	32687490
Pubmed	Functional proteomics establishes the interaction of SIRT7 with chromatin remodeling complexes and expands its role in regulation of RNA polymerase I transcription.	ANXA1 CAPN1 NOC3L CHD1 CHD2 PSMD12 UPF1 TEX10 TASOR2 IGF2BP3 MTOR AHNAK SYNE2 GNL2 TJP2 PLEC ATP1A1	1.34e-09	653	140	17	22586326
Pubmed	A High-Density Human Mitochondrial Proximity Interaction Network.	HNRNPDL PALD1 TBRG4 VWA8 CFAP36 MTERF3 RANBP6 RTN3 RTN4IP1 UPF1 FLG2 TTC3 NBAS IGF2BP3 PDE12 SPATS2L AKAP9 OSBPL3 SYNE2 GNL2 SASS6 ATP1A1 HERC1 SLC33A1 MMUT	1.44e-09	1496	140	25	32877691
Pubmed	A protein-interaction network of interferon-stimulated genes extends the innate immune system landscape.	PALD1 TBRG4 PLOD3 VWA8 GLRX3 NOC3L RANBP6 L2HGDH PSMD12 UPF1 RFC2 LDHA WDR26 NBAS IGF2BP3 COMMD8 MTOR AHNAK SYNE2 EHD1 GNL2 TJP2 ATP1A1 EIF3M	3.39e-09	1440	140	24	30833792
Pubmed	Proteomic profiling of VCP substrates links VCP to K6-linked ubiquitylation and c-Myc function.	HNRNPDL ANXA1 CAPN1 NOC3L CHD1 CHD2 UPF1 SRBD1 RFC2 TEX10 LDHA NCOR2 PDE12 MAP4K5 AHNAK EHD1 AHCY GSDMA PLCG2 PLEC MMP14 EIF3M	2.57e-08	1353	140	22	29467282
Pubmed	Targeting USP10 induces degradation of oncogenic ANLN in esophageal squamous cell carcinoma.	HNRNPDL PLOD3 ANXA1 CAPN1 NOC3L UPF1 SRBD1 RFC2 FLG2 TEX10 LDHA TASOR2 SPATS2L AHNAK AHCY GNL2 TJP2 GSDMA PLEC PATJ EIF3M	3.50e-08	1257	140	21	36526897
Pubmed	Ski regulates Hippo and TAZ signaling to suppress breast cancer progression.	STK38 LDHA WDR26 AHNAK PLEC ATP1A1 STK38L	5.15e-08	84	140	7	25670202
Pubmed	∆F508 CFTR interactome remodelling promotes rescue of cystic fibrosis.	ANXA1 PSMD12 UPF1 RFC2 FLG2 LDHA AKAP12 IGF2BP3 MTOR AHNAK EHD1 AHCY GSDMA PLEC EIF3M	6.05e-08	647	140	15	26618866
Pubmed	BioID-based intact cell interactome of the Kv1.3 potassium channel identifies a Kv1.3-STAT3-p53 cellular signaling pathway.	PALD1 DSC2 GLRX3 STK38 PSMD12 NIBAN2 UPF1 AKAP12 FBXO5 MAP4K5 AHNAK EHD1 AHCY ATP1A1 PATJ	1.92e-07	708	140	15	39231216
Pubmed	A high-throughput approach for measuring temporal changes in the interactome.	RNASEH2B GLRX3 CAPN1 RANBP6 IREB2 PSMD12 NIBAN2 RFC2 LDHA WDR26 AKAP12 IGF2BP3 PDE12 MTOR AHNAK EHD1 AHCY TJP2 PLEC HERC1 EIF3M	3.97e-07	1455	140	21	22863883
Pubmed	Hepatitis B Virus HBx Protein Mediates the Degradation of Host Restriction Factors through the Cullin 4 DDB1 E3 Ubiquitin Ligase Complex.	ADGRB1 OBSCN L2HGDH PSMD12 UPF1 FLG2 TEX10 WDR26 MTOR GSDMA	4.73e-07	304	140	10	32235678
Pubmed	HDLBP Promotes Hepatocellular Carcinoma Proliferation and Sorafenib Resistance by Suppressing Trim71-dependent RAF1 Degradation.	VWA8 ANXA1 IREB2 CHD2 UPF1 RFC2 FLG2 TEX10 LDHA IGF2BP3 SPATS2L AKAP9 OSBPL3 AHNAK EHD1 AHCY GNL2 TJP2 PLEC ATP1A1	6.56e-07	1371	140	20	36244648
Pubmed	Defining the human deubiquitinating enzyme interaction landscape.	VWA8 ANXA1 NOC3L ADGRB1 PSMD12 NIBAN2 SRBD1 RFC2 TEX10 WDR26 LIN7A PDE12 GNL2 TJP2 SASS6 PLEC EIF3M	6.66e-07	1005	140	17	19615732
Pubmed	Inhibition of calpain 1 restores plasma membrane stability to pharmacologically rescued Phe508del-CFTR variant.	HNRNPDL PLOD3 ANXA1 CAPN1 FLG2 LDHA IGF2BP3 AHNAK AHCY TJP2 PLEC ATP1A1	7.33e-07	488	140	12	31324722
Pubmed	CHK2-BRCA1 tumor-suppressor axis restrains oncogenic Aurora-A kinase to ensure proper mitotic microtubule assembly.	HNRNPDL ANXA1 PSMD12 UPF1 LDHA AKAP12 IGF2BP3 PDE12 AHNAK AHCY PLEC EIF3M	8.33e-07	494	140	12	26831064
Pubmed	Multiplexed kinase interactome profiling quantifies cellular network activity and plasticity.	PLOD3 ANXA1 RPS6KA2 STK38 CHD1 CHD2 TEX10 WDR26 NCOR2 AKAP9 MAP4K5 AHCY PLEC CPLANE1 STK38L EIF3M	8.80e-07	910	140	16	36736316
Pubmed	BPA modulates the WDR5/TET2 complex to regulate ERβ expression in eutopic endometrium and drives the development of endometriosis.	HNRNPDL SQLE PSMD12 UPF1 LDHA IGF2BP3 KMT2D PDE12 SPATS2L EHD1 TJP2 PLEC ATP1A1 EIF3M	1.19e-06	711	140	14	33022573
Pubmed	A Degradation Motif in STAU1 Defines a Novel Family of Proteins Involved in Inflammation.	HNRNPDL ANXA1 CAPN1 SMG5 NIBAN2 UPF1 TTC3 AKAP12 IGF2BP3 SPATS2L AHNAK TJP2 PLEC ATP1A1	1.48e-06	724	140	14	36232890
Pubmed	Comprehensive interactome profiling of the human Hsp70 network highlights functional differentiation of J domains.	PLOD3 DSC2 VWA8 MTERF3 APAF1 NOC3L RTN3 CHD1 RTN4IP1 NIBAN2 UPF1 TTC3 AKAP12 NBAS PDE12 AKAP9 MAP4K5 SYNE2 GNL2 SLC33A1	2.27e-06	1487	140	20	33957083
Pubmed	A dual-activity topoisomerase complex regulates mRNA translation and turnover.	DOCK3 PALD1 PLOD3 VWA8 RPS6KA2 OBSCN SMG5 TTC3 NCOR2 KMT2D MTOR AHNAK KIFC3 PLEC HERC1 MMP14 TJP3	2.41e-06	1105	140	17	35748872
Pubmed	Claudin-4 localization in epithelial ovarian cancer.	DSC2 AKAP12 AHNAK EHD1 ATP1A1	2.65e-06	54	140	5	36237976
Pubmed	SPATA2 Links CYLD to LUBAC, Activates CYLD, and Controls LUBAC Signaling.	HNRNPDL STK38 UPF1 FLG2 SPATS2L AHNAK CCDC87 GSDMA PLEC ATP1A1 STK38L EIF3M	2.93e-06	558	140	12	27591049
Pubmed	The basic helix-loop-helix proteins differentiated embryo chondrocyte (DEC) 1 and DEC2 function as corepressors of retinoid X receptors.	BHLHE41 BHLHE40 NCOR2	3.52e-06	8	140	3	19786558
Pubmed	Rho-associated protein kinase-dependent moesin phosphorylation is required for PD-L1 stabilization in breast cancer.	HNRNPDL TBRG4 CAPN1 PSMD12 FLG2 LDHA MTOR GSDMA	3.76e-06	224	140	8	32941674
Pubmed	Tumor suppressor BAP1 nuclear import is governed by transportin-1.	HNRNPDL GLRX3 ANXA1 STK38 PSMD12 UPF1 RFC2 LDHA WDR26 AKAP12 IGF2BP3 AHNAK AHCY PLEC ATP1A1 PATJ STK38L	4.04e-06	1149	140	17	35446349
Pubmed	Assembly of the U5 snRNP component PRPF8 is controlled by the HSP90/R2TP chaperones.	HNRNPDL TBRG4 PLOD3 VWA8 GLRX3 ANXA1 CHD1 UPF1 RFC2 FLG2 LDHA IGF2BP3 AHNAK SYNE2 AHCY GNL2 PLEC ATP1A1 EIF3M	4.28e-06	1415	140	19	28515276
Pubmed	Systematic analysis of human protein complexes identifies chromosome segregation proteins.	HNRNPDL STK38 XDH NIBAN2 NRIP3 AKAP12 TASOR2 NBAS IGF2BP3 KANSL2 FBXO5 AHNAK AHCY SASS6 CEP152 KIFC3 EIF3M	4.33e-06	1155	140	17	20360068
Pubmed	Gain of Additional BIRC3 Protein Functions through 3'-UTR-Mediated Protein Complex Formation.	HNRNPDL DNHD1 TBRG4 PDGFRB NOC3L RTN3 CHD1 PSMD12 UPF1 RFC2 LDHA TTC3 JARID2 PDE12 MTOR AHCY GNL2 ATP1A1 EIF3M	4.73e-06	1425	140	19	30948266
Pubmed	Loss of ER retention motif of AGR2 can impact mTORC signaling and promote cancer metastasis.	GLRX3 ANXA1 CAPN1 RTN3 PSMD12 NIBAN2 UPF1 LDHA NBAS AKAP9 AHNAK AHCY PLEC ATP1A1	5.15e-06	807	140	14	30575818
Pubmed	Functional proteomics mapping of a human signaling pathway.	GLRX3 LAMA4 RANBP6 NIBAN2 TEX10 TTC3 NCOR2 KMT2D PLCG2 PLEC HERC1 INVS	5.26e-06	591	140	12	15231748
Pubmed	SARS-CoV-2 N Protein Antagonizes Stress Granule Assembly and IFN Production by Interacting with G3BPs to Facilitate Viral Replication.	IREB2 FLG2 NCOR2 IGF2BP3 SPATS2L AHNAK HERC1 STK38L	7.26e-06	245	140	8	35652658
Pubmed	Proteomic analysis of human parotid gland exosomes by multidimensional protein identification technology (MudPIT).	PLOD3 DSC2 ANXA1 CAPN1 LAMA4 AHNAK EHD1 TXNDC16 PLEC ATP1A1	7.92e-06	417	140	10	19199708
Pubmed	Chemical Crosslinking Mass Spectrometry Analysis of Protein Conformations and Supercomplexes in Heart Tissue.	VWA8 OBSCN RTN4IP1 UPF1 MECR PLEC ATP1A1 CPLANE1 MMUT	8.45e-06	331	140	9	29199018
Pubmed	The multi-subunit GID/CTLH E3 ubiquitin ligase promotes cell proliferation and targets the transcription factor Hbp1 for degradation.	VWA8 CHD1 PSMD12 UPF1 TEX10 WDR26 GNL2 EIF3M	9.17e-06	253	140	8	29911972
Pubmed	Quantitative study of the interactome of PKCζ involved in the EGF-induced tumor cell chemotaxis.	STK38 RANBP6 PSMD12 WDR26 CEP152 FGD6 EIF3M	1.03e-05	184	140	7	23402259
Pubmed	A central chaperone-like role for 14-3-3 proteins in human cells.	DSC2 RPS6KA2 WDR26 AKAP9 MTOR OSBPL3 AHNAK SYNE2 TJP2 FNIP1 CEP152 PLEC PATJ FGD6	1.07e-05	861	140	14	36931259
Pubmed	Mouse screen reveals multiple new genes underlying mouse and human hearing loss.	RNASEH2B DSC2 CFAP36 SQLE ADGRB1 PRAMEF2 LDHA BHLHE40 JARID2 AKAP9 MECR MTOR OSBPL3 EHD1 KDM8 HERC1 ST18	1.12e-05	1242	140	17	30973865
Pubmed	HSF1 phosphorylation establishes an active chromatin state via the TRRAP-TIP60 complex and promotes tumorigenesis.	HNRNPDL VWA8 STK38 PSMD12 UPF1 NCOR2 IGF2BP3 SYNE2 GRIP2 KDM8 PLCG2 SLC33A1 EIF3M	1.21e-05	754	140	13	35906200
Pubmed	Arginine methylation and ubiquitylation crosstalk controls DNA end-resection and homologous recombination repair.	HNRNPDL STK38 UPF1 SRBD1 LDHA WDR26 TASOR2 IGF2BP3 AHCY PLEC STK38L	1.54e-05	551	140	11	34728620
Pubmed	Regulation of membrane-type 1 matrix metalloproteinase expression by zonula occludens-2 in human lung cancer cells.	TJP2 MMP14	1.61e-05	2	140	2	23605953
Pubmed	NDR functions as a physiological YAP1 kinase in the intestinal epithelium.	STK38 STK38L	1.61e-05	2	140	2	25601544
Pubmed	Identification of functional hypoxia response elements in the promoter region of the DEC1 and DEC2 genes.	BHLHE41 BHLHE40	1.61e-05	2	140	2	12354771
Pubmed	Antitumor effect of dimethyl itaconate on thymic carcinoma by targeting LDHA-mTOR axis.	LDHA MTOR	1.61e-05	2	140	2	34293399
Pubmed	Mice lacking the circadian modulators SHARP1 and SHARP2 display altered sleep and mixed state endophenotypes of psychiatric disorders.	BHLHE41 BHLHE40	1.61e-05	2	140	2	25340473
Pubmed	The activation of lactate dehydrogenase induced by mTOR drives neoplastic change in breast epithelial cells.	LDHA MTOR	1.61e-05	2	140	2	30138330
Pubmed	Disturbed clockwork resetting in Sharp-1 and Sharp-2 single and double mutant mice.	BHLHE41 BHLHE40	1.61e-05	2	140	2	18648504
Pubmed	The Potential Roles of Dec1 and Dec2 in Periodontal Inflammation.	BHLHE41 BHLHE40	1.61e-05	2	140	2	34638690
Pubmed	CHD1 and CHD2 are positive regulators of HIV-1 gene expression.	CHD1 CHD2	1.61e-05	2	140	2	25297984
Pubmed	Alteration of PDGFRβ-Akt-mTOR pathway signaling in fibrosarcomatous transformation of dermatofibrosarcoma protuberans.	PDGFRB MTOR	1.61e-05	2	140	2	28711648
Pubmed	Deimination of human filaggrin-2 promotes its proteolysis by calpain 1.	CAPN1 FLG2	1.61e-05	2	140	2	21531719
Pubmed	CED-4 is an mRNA-binding protein that delivers ced-3 mRNA to ribosomes.	APAF1 IFT43	1.61e-05	2	140	2	26740177
Pubmed	BHLHE40/41 regulate microglia and peripheral macrophage responses associated with Alzheimer's disease and other disorders of lipid-rich tissues.	BHLHE41 BHLHE40	1.61e-05	2	140	2	38448474
Pubmed	UPF1 impacts on mTOR signaling pathway and autophagy in endometrioid endometrial carcinoma.	UPF1 MTOR	1.61e-05	2	140	2	34520393
Pubmed	Hypomethylation associated vitamin D receptor expression in ATP1A1 mutant aldosterone-producing adenoma.	ATP1A1 VDR	1.61e-05	2	140	2	35257799
Pubmed	Inversin, a novel gene in the vertebrate left-right axis pathway, is partially deleted in the inv mouse.	TEX10 INVS	1.61e-05	2	140	2	9771707
Pubmed	Altered Stra13 and Dec2 circadian gene expression in hypoxic cells.	BHLHE41 BHLHE40	1.61e-05	2	140	2	18342625
Pubmed	A proprotein convertase/MMP-14 proteolytic cascade releases a novel 40 kDa vasculostatin from tumor suppressor BAI1.	ADGRB1 MMP14	1.61e-05	2	140	2	22330140
Pubmed	DEC1 negatively regulates the expression of DEC2 through binding to the E-box in the proximal promoter.	BHLHE41 BHLHE40	1.61e-05	2	140	2	12624110
Pubmed	Basic helix-loop-helix transcription factors DEC1 and DEC2 regulate the paclitaxel-induced apoptotic pathway of MCF-7 human breast cancer cells.	BHLHE41 BHLHE40	1.61e-05	2	140	2	21327324
Pubmed	A case of interdigitating dendritic cell sarcoma studied by whole-exome sequencing.	FNIP1 POLQ	1.61e-05	2	140	2	30099721
Pubmed	Regulation of NDR2 protein kinase by multi-site phosphorylation and the S100B calcium-binding protein.	STK38 STK38L	1.61e-05	2	140	2	15037617
Pubmed	Defining the proximal interaction networks of Arf GTPases reveals a mechanism for the regulation of PLD1 and PI4KB.	HNRNPDL DSC2 CFAP36 NOC3L FLG2 LDHA AKAP12 TASOR2 IGF2BP3 AHNAK EHD1 TJP2 ATP1A1	1.66e-05	777	140	13	35844135
Pubmed	PKCε promotes oncogenic functions of ATF2 in the nucleus while blocking its apoptotic function at mitochondria.	ANXA1 LDHA S100A2 AHNAK AHCY ATP1A1	1.95e-05	136	140	6	22304920
Pubmed	Comparative proximity biotinylation implicates the small GTPase RAB18 in sterol mobilization and biosynthesis.	PALD1 DSC2 STK38 NIBAN2 AKAP12 NBAS AHNAK SYNE2 EHD1 AHCY SLC33A1	2.04e-05	568	140	11	37774976
Pubmed	High-sensitivity profiling of SARS-CoV-2 noncoding region-host protein interactome reveals the potential regulatory role of negative-sense viral RNA.	HNRNPDL PSMD12 UPF1 SRBD1 LDHA IGF2BP3 SPATS2L AHCY ATP1A1 EIF3M	2.18e-05	469	140	10	37314180
Pubmed	Quantitative Proteomics Links the LRRC59 Interactome to mRNA Translation on the ER Membrane.	PALD1 ABCA3 DSC2 RTN3 UPF1 NBAS IGF2BP3 SPATS2L SYNE2	2.27e-05	375	140	9	32788342
Pubmed	EZH2 interacts with HP1BP3 to epigenetically activate WNT7B that promotes temozolomide resistance in glioblastoma.	HNRNPDL DNAH3 PLOD3 ANXA1 NOC3L PSMD12 UPF1 FLG2 LDHA AHNAK AHCY PLEC ATP1A1	2.34e-05	803	140	13	36517590
Pubmed	Targeting Novel Sodium Iodide Symporter Interactors ADP-Ribosylation Factor 4 and Valosin-Containing Protein Enhances Radioiodine Uptake.	ANXA1 LDHA EHD1	2.80e-05	15	140	3	31672844
Pubmed	Brain-specific angiogenesis inhibitor-1 signaling, regulation, and enrichment in the postsynaptic density.	ADGRB1 LIN7A PATJ	2.80e-05	15	140	3	23782696
Pubmed	KAP1 facilitates reinstatement of heterochromatin after DNA replication.	HNRNPDL CAPN1 APAF1 PSMD12 UPF1 RFC2 NBAS IGF2BP3 PDE12 MTOR AHCY ATP1A1	2.97e-05	704	140	12	29955894
Pubmed	Construction of long-transcript enriched cDNA libraries from submicrogram amounts of total RNAs by a universal PCR amplification method.	HNRNPDL OBSCN RTN4IP1 CHD2 PRAMEF2 TTC3 AKAP12 OSBPL3 TJP2 PLEC HERC1 PATJ CPLANE1 SLC33A1 UBE2Q2	3.35e-05	1084	140	15	11544199
Pubmed	Impaired plasma membrane localization of ubiquitin ligase complex underlies 3-M syndrome development.	MTERF3 APAF1 CHD1 PSMD12 TASOR2 SPATS2L FNIP1 PLEC POLQ EIF3M	3.49e-05	496	140	10	31343991
Pubmed	An important role for CDK2 in G1 to S checkpoint activation and DNA damage response in human embryonic stem cells.	ANXA1 UPF1 FLG2 LDHA IGF2BP3 AHNAK AHCY PLEC ATP1A1	3.53e-05	397	140	9	21319273
Pubmed	A human skeletal muscle interactome centered on proteins involved in muscular dystrophies: LGMD interactome.	OBSCN LAMA4 CHD2 TTC3 AKAP12 AKAP9 SYNE2 PLEC ATP1A1 TNNT3	3.55e-05	497	140	10	23414517
Pubmed	DNA microarray analysis of genes involved in p53 mediated apoptosis: activation of Apaf-1.	COL19A1 ANXA1 APAF1 PLEC	3.60e-05	46	140	4	11423996
Pubmed	The Interleukin-2-mTORc1 Kinase Axis Defines the Signaling, Differentiation, and Metabolism of T Helper 1 and Follicular B Helper T Cells.	RALGDS ANXA1 STK38 FBXO5 MTOR SASS6 PLCG2	3.96e-05	227	140	7	26410627
Pubmed	mTORC2 interactome and localization determine aggressiveness of high-grade glioma cells through association with gelsolin.	UPF1 FLG2 LDHA MTOR AHNAK GSDMA PLEC ATP1A1	4.11e-05	312	140	8	37120454
Pubmed	HEY1 functions are regulated by its phosphorylation at Ser-68.	STK38 AKAP9 SYNE2 PLEC STK38L	4.26e-05	95	140	5	27129302
Pubmed	STING-Mediated IFI16 Degradation Negatively Controls Type I Interferon Production.	NOC3L OBSCN STK38 PSMD12 SRBD1 RFC2 SPATS2L GNL2	4.50e-05	316	140	8	31665637
Pubmed	USP7 targets XIAP for cancer progression: Establishment of a p53-independent therapeutic avenue for glioma.	DNHD1 FLG2 IGF2BP3 KMT2D AHNAK PLEC HERC1	4.80e-05	234	140	7	36243803
Pubmed	Human NDR kinases control G(1)/S cell cycle transition by directly regulating p21 stability.	STK38 STK38L	4.81e-05	3	140	2	21262772
Pubmed	Involvement of SMRT corepressor in transcriptional repression by the vitamin D receptor.	NCOR2 VDR	4.81e-05	3	140	2	19098224
Pubmed	Bone marrow-derived mesenchymal stem cells up-regulate acetylcholine receptor delta subunit through NRG/ErbB3-mediated mitogen-activated protein kinase pathway.	ERBB3 CHRND	4.81e-05	3	140	2	22376253
Pubmed	Cyclin D1 promotes cell cycle progression through enhancing NDR1/2 kinase activity independent of cyclin-dependent kinase 4.	STK38 STK38L	4.81e-05	3	140	2	23897809
Pubmed	Immunohistochemical expression of PDGFR, VEGF-C, and proteins of the mToR pathway before and after androgen deprivation therapy in prostate carcinoma: significant decrease after treatment.	PDGFRB MTOR	4.81e-05	3	140	2	24243494
Pubmed	LINC complex-Lis1 interplay controls MT1-MMP matrix digest-on-demand response for confined tumor cell migration.	SYNE2 MMP14	4.81e-05	3	140	2	29934494
Pubmed	Positive prognostic value of HER2-HER3 co-expression and p-mTOR in gastric cancer patients.	ERBB3 MTOR	4.81e-05	3	140	2	29233126
Pubmed	DHX34 and NBAS form part of an autoregulatory NMD circuit that regulates endogenous RNA targets in human cells, zebrafish and Caenorhabditis elegans.	UPF1 NBAS	4.81e-05	3	140	2	23828042
Pubmed	Calpain inhibition rescues troponin T3 fragmentation, increases Cav1.1, and enhances skeletal muscle force in aging sedentary mice.	CAPN1 TNNT3	4.81e-05	3	140	2	26892246
Pubmed	Regulation of the Mechanism of TWIST1 Transcription by BHLHE40 and BHLHE41 in Cancer Cells.	BHLHE41 BHLHE40	4.81e-05	3	140	2	26391953
Pubmed	Human mismatch repair gene, MLH1, is transcriptionally repressed by the hypoxia-inducible transcription factors, DEC1 and DEC2.	BHLHE41 BHLHE40	4.81e-05	3	140	2	18345027
Pubmed	Roles of ZO-1 and ZO-2 in establishment of the belt-like adherens and tight junctions with paracellular permselective barrier function.	TJP2 TJP3	4.81e-05	3	140	2	19538286
Pubmed	TFEB Transcriptional Responses Reveal Negative Feedback by BHLHE40 and BHLHE41.	BHLHE41 BHLHE40	4.81e-05	3	140	2	33176151
Pubmed	Different effects of ZO-1, ZO-2 and ZO-3 silencing on kidney collecting duct principal cell proliferation and adhesion.	TJP2 TJP3	4.81e-05	3	140	2	25486565
Pubmed	A role for AKT1 in nonsense-mediated mRNA decay.	UPF1 MTOR	4.81e-05	3	140	2	34634811
Pubmed	Bhlhe40 and Bhlhe41 transcription factors regulate alveolar macrophage self-renewal and identity.	BHLHE41 BHLHE40	4.81e-05	3	140	2	31414712
Pubmed	CHD1 and SPOP synergistically protect prostate epithelial cells from DNA damage.	CHD1 CHD2	4.81e-05	3	140	2	33022763
Pubmed	The carboxyl terminus of zona occludens-3 binds and recruits a mammalian homologue of discs lost to tight junctions.	PATJ TJP3	4.81e-05	3	140	2	12021270
Pubmed	Hypoxia-inducible factor 1 regulation through cross talk between mTOR and MT1-MMP.	MTOR MMP14	4.81e-05	3	140	2	24164895
Pubmed	An unusual arrangement of two 14-3-3-like domains in the SMG5-SMG7 heterodimer is required for efficient nonsense-mediated mRNA decay.	SMG5 UPF1	4.81e-05	3	140	2	23348841
GeneFamily	PDZ domain containing	LIN7A AHNAK TJP2 GRIP2 PATJ TJP3	1.05e-04	152	89	6	1220
GeneFamily	PDZ domain containing\|Crumbs complex	LIN7A PATJ	8.43e-04	9	89	2	1223
Coexpression	GSE17301_CTRL_VS_48H_ACD3_ACD28_STIM_CD8_TCELL_DN	PLA2G7 RALGDS NUDT7 ANXA1 SQLE EHD1 GSDMA MMP14 ST18	1.36e-06	200	140	9	M8046
Coexpression	BERENJENO_TRANSFORMED_BY_RHOA_DN	PLA2G7 RALGDS PDGFRB LAMA4 XDH TTC3 BHLHE40 AKAP12 TXNDC16 MMP14 VDR	1.02e-05	398	140	11	M7514
Coexpression	GSE2585_CTEC_VS_THYMIC_MACROPHAGE_DN	BHLHE41 ANXA1 RPS6KA2 TTC3 KMT2D FNIP1 CEP152 PLEC	1.22e-05	199	140	8	M6264
Coexpression	GSE9650_NAIVE_VS_MEMORY_CD8_TCELL_UP	RPS6KA2 SQLE TTC3 WDR26 JARID2 KANSL2 AKAP9 MECR	1.26e-05	200	140	8	M5831
Coexpression	GSE339_EX_VIVO_VS_IN_CULTURE_CD4CD8DN_DC_DN	COL19A1 LAMA4 WDR26 BHLHE40 JARID2 EHD1 PLEC ATP1A1	1.26e-05	200	140	8	M5135
Coexpression	KAECH_NAIVE_VS_MEMORY_CD8_TCELL_UP	SQLE TTC3 WDR26 JARID2 KANSL2 AKAP9 MECR PATJ	1.26e-05	200	140	8	M3020
Coexpression	BERENJENO_TRANSFORMED_BY_RHOA_DN	PLA2G7 RALGDS PDGFRB LAMA4 XDH TTC3 BHLHE40 AKAP12 TXNDC16 MMP14 VDR	1.71e-05	421	140	11	MM985
Coexpression	PGF_UP.V1_UP	RFK IREB2 MMRN1 AKAP9 SYNE2 STK38L SLC33A1	7.51e-05	190	140	7	M2674
Coexpression	MURARO_PANCREAS_MESENCHYMAL_STROMAL_CELL	PDGFRB ANXA1 LAMA4 LDHA BHLHE40 AKAP12 JARID2 SPATS2L HMCN1 AHNAK STK38L EIF3M VDR	7.68e-05	681	140	13	M39175
Coexpression	NAKAYA_MONOCYTE_FLUMIST_AGE_18_50YO_7DY_DN	DSC2 STK38 CHD1 CHD2 BHLHE40 MTOR EHD1 INVS	8.14e-05	260	140	8	M41075
Coexpression	GSE20484_MCSG_VS_CXCL4_MONOCYTE_DERIVED_MACROPHAGE_DN	ABCA3 SMG5 JARID2 AHNAK HERC1 STK38L SENP7	8.83e-05	195	140	7	M7382
Coexpression	GSE16450_IMMATURE_VS_MATURE_NEURON_CELL_LINE_UP	TRPV1 NUDT7 VNN2 SYNE2 TXNDC16 HERC1 SENP7	8.83e-05	195	140	7	M7397
Coexpression	GSE22886_NAIVE_VS_IGG_IGA_MEMORY_BCELL_DN	BHLHE41 RALGDS BHLHE40 AHNAK EHD1 PLCG2 ATP1A1	9.12e-05	196	140	7	M4433
Coexpression	ERBB2_UP.V1_DN	MTERF3 NOC3L RANBP6 CHD1 FBXO5 FKTN GNL2	9.42e-05	197	140	7	M2635
Coexpression	GSE17186_MEMORY_VS_CD21HIGH_TRANSITIONAL_BCELL_UP	DOCK3 ERBB3 L2HGDH TEX10 GNL2 PATJ TJP3	9.72e-05	198	140	7	M7200
Coexpression	GSE24142_DN2_VS_DN3_THYMOCYTE_ADULT_DN	MTERF3 WDR26 TASOR2 KANSL2 PDE12 AKAP9 HERC1	1.00e-04	199	140	7	M4567
Coexpression	GSE21774_CD62L_POS_CD56_DIM_VS_CD62L_NEG_CD56_DIM_NK_CELL_DN	TBRG4 PLOD3 COL19A1 RPS6KA2 GRIP2 KIFC3 KIF17	1.00e-04	199	140	7	M7496
Coexpression	GSE5589_LPS_VS_LPS_AND_IL6_STIM_MACROPHAGE_45MIN_DN	TBRG4 VWA8 CAPN1 SMG5 PDE12 DTWD1 MECR	1.00e-04	199	140	7	M6612
Coexpression	GSE7460_WT_VS_FOXP3_HET_ACT_TCONV_UP	ACAP1 ERBB3 RPS6KA2 SYNE2 SHE PLEC SENP7	1.00e-04	199	140	7	M5709
Coexpression	GSE28737_BCL6_HET_VS_BCL6_KO_FOLLICULAR_BCELL_UP	TRPV1 IFT172 RPS6KA2 NRIP3 IFT43 NBAS AKAP9	1.03e-04	200	140	7	M9380
Coexpression	GSE12198_LOW_IL2_STIM_NK_CELL_VS_HIGH_IL2_STIM_NK_CELL_UP	HNRNPDL TBRG4 IREB2 UPF1 NCOR2 MECR ATP1A1	1.03e-04	200	140	7	M7064
Coexpression	GSE33425_CD161_INT_VS_NEG_CD8_TCELL_DN	RFK ANXA1 IREB2 CHD1 AHNAK TXNDC16 PLCG2	1.03e-04	200	140	7	M8543
Coexpression	GSE15930_NAIVE_VS_72H_IN_VITRO_STIM_IL12_CD8_TCELL_DN	RNASEH2B SQLE XDH PSMD12 RFC2 BHLHE40 AHNAK	1.03e-04	200	140	7	M3610
Coexpression	GSE3039_ALPHAALPHA_VS_ALPHABETA_CD8_TCELL_UP	PALD1 TBRG4 NIBAN2 LDHA BHLHE40 FGD6 VDR	1.03e-04	200	140	7	M6476
Coexpression	GSE17721_LPS_VS_GARDIQUIMOD_16H_BMDC_DN	TBRG4 VWA8 NCOR2 MECR MAP4K5 AHNAK MMUT	1.03e-04	200	140	7	M4062
Coexpression	GSE17721_0.5H_VS_4H_CPG_BMDC_DN	RFK PDGFRB ANXA1 RPS6KA2 PSMD12 VNN2 SYNE2	1.03e-04	200	140	7	M4125
Coexpression	MURARO_PANCREAS_DUCTAL_CELL	PLA2G7 ERBB3 DSC2 ANXA1 RPS6KA2 CAPN1 STK38 NIBAN2 LDHA BHLHE40 SPATS2L AHNAK SYNE2 TJP2 ATP1A1 PATJ STK38L FGD6	1.60e-04	1276	140	18	M39173
Coexpression	GSE3720_UNSTIM_VS_LPS_STIM_VD2_GAMMADELTA_TCELL_DN	ANXA1 APAF1 XDH SPATS2L OSBPL3 AHNAK	1.77e-04	153	140	6	M6338
ToppCell	NS-control\|NS / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	ERBB3 ANXA1 NIBAN2 S100A2 AKAP9 AHNAK SYNE2 TJP2 ATP1A1 CPLANE1	8.35e-10	200	140	10	ecbe89ff95d046155b984c8c150e0b9e7278f839
ToppCell	control\|World / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls	ERBB3 ANXA1 NIBAN2 AKAP9 AHNAK SYNE2 TJP2 ATP1A1 CPLANE1	1.50e-08	200	140	9	97f36d2c197e03d93a1fc59949d77ae90f6e6a9a
ToppCell	(03)_KRT6B+-(1)_GFP\|(03)_KRT6B+ / shred by cell type by condition	RALGDS ANXA1 LDHA S100A2 JARID2 EHD1 PLEC MMP14	2.31e-07	199	140	8	10493933a3dc330e40595ec0c001428b9d68f17e
ToppCell	(01)_IL1RL1+-(2)_GFP_FOXI1\|(01)_IL1RL1+ / shred by cell type by condition	BHLHE41 PSMD12 TTC3 AKAP12 SPATS2L AKAP9 SYNE2 EIF3M	2.31e-07	199	140	8	a2f7d0cabf35b80fe239fae34a77bf9344d5d743
ToppCell	NS-moderate-d_0-4-Epithelial\|d_0-4 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	ANXA1 TTC3 IFT43 AKAP9 AHNAK TJP2 ATP1A1 CPLANE1	2.40e-07	200	140	8	64462a18afca3c1a8548a857924b8166058bf958
ToppCell	Smart-seq2-tissue-resident_(Smart-seq2)-myeloid-myeloid_dendritic-liver_dendritic_cell\|tissue-resident_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type	APAF1 IGF2BP3 CHRD TNNT3 KIF17 ST18 FGD6	5.89e-07	154	140	7	acfbde0fbc09fd69af62a81f8f63e14e36dd1ae0
ToppCell	droplet-Heart-nan-18m-Mesenchymal-smooth_muscle_cell\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	COL19A1 PDGFRB IFT43 LIN7A OSBPL3 GRIP2 KIF17	2.16e-06	187	140	7	59313a47a6012b2413d7d3673bb05fb7e49fd88f
ToppCell	droplet-Heart-nan-18m-Mesenchymal-smooth_muscle_cell\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	COL19A1 PDGFRB IFT43 LIN7A OSBPL3 GRIP2 KIF17	2.16e-06	187	140	7	2591fe1552cd10925ad1d8d1f062a057ce6bdad9
ToppCell	LPS-antiTNF-Epithelial_alveolar-AT_1-Differentiating_AT2\|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	ABCA3 NIBAN2 OSBPL3 SYNE2 KIFC3 PATJ TJP3	2.16e-06	187	140	7	58d48128547ee3513d0bf7f78e61b76b1c472ca9
ToppCell	droplet-Pancreas-PANCREAS-30m-Epithelial-pancreatic_B_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	RPS6KA2 TTC3 AKAP9 FNIP1 HERC1 ST18 VDR	2.85e-06	195	140	7	3e519cffa6144a62b06124642a14c9ff39b76554
ToppCell	droplet-Pancreas-PANCREAS-30m-Epithelial-pancreatic_B_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	RPS6KA2 TTC3 AKAP9 FNIP1 HERC1 ST18 VDR	2.85e-06	195	140	7	7796ea9247f4c63762f0de8490fed08b9717fa23
ToppCell	mLN-T_cell-Th1\|T_cell / Region, Cell class and subclass	BHLHE41 ANXA1 NRIP3 BHLHE40 CHRND AHNAK DUSP10	3.05e-06	197	140	7	5e39a49dddef04469ff2b615d755ddf6a926e58e
ToppCell	LPS_anti-TNF-Epithelial_alveolar-AT_1-Differentiating_AT2\|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type	ABCA3 AKAP9 SYNE2 KIFC3 ATP1A1 PATJ TJP3	3.05e-06	197	140	7	3d13a4f2e86422900ee2194e8a1fd1cf9750d5d3
ToppCell	5'-Airway_Nasal-Epithelial-Epithelial_transtional-secretory-nasal_mucosa_goblet_cell-Goblet_(nasal)-Goblet_(nasal)_L.0.2.2.0\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	DNAH3 ANXA1 S100A2 AHNAK PLEC CPLANE1 TJP3	3.05e-06	197	140	7	5c4cee914baf7cb43e9cb99cc9e3ae823856dc15
ToppCell	mLN-T_cell-Th1\|mLN / Region, Cell class and subclass	ANXA1 NRIP3 BHLHE40 CHRND AHNAK SHE DUSP10	3.15e-06	198	140	7	7627b7c3a248da2bd5e1e6f7c226e5fd0bc92113
ToppCell	mLN-(1)_T_cell-(12)_Th1\|mLN / shred on region, Cell_type, and subtype	ANXA1 NRIP3 BHLHE40 CHRND AHNAK SHE DUSP10	3.15e-06	198	140	7	1fe8257233232b264b9ca630c2d92c509a195353
ToppCell	LPS_only-Epithelial_alveolar\|LPS_only / Treatment groups by lineage, cell group, cell type	ABCA3 ANXA1 SQLE SYNE2 KIFC3 ATP1A1 TJP3	3.15e-06	198	140	7	655df75b9692d815c7f6910275e1f684ac63bf62
ToppCell	(11)_FOXN4+-(2)_GFP_FOXI1\|(11)_FOXN4+ / shred by cell type by condition	RFK CHD1 PSMD12 TTC3 AKAP9 MAP4K5 SYNE2	3.15e-06	198	140	7	76d40b8c2f8399725b3a62ee2ae0896559cf91eb
ToppCell	(00)_Basal-(2)_GFP_FOXI1\|(00)_Basal / shred by cell type by condition	BHLHE41 PSMD12 TTC3 AKAP12 SPATS2L AKAP9 SYNE2	3.26e-06	199	140	7	19674e1eaeb51e4196d847cb62aa437c852951d3
ToppCell	Transverse-Macrophage-LYVE1_Macrophage\|Macrophage / Region, Cell class and subclass	BHLHE41 DNHD1 NEURL2 IFT172 FLG2 IFT43 MTOR	3.26e-06	199	140	7	fd75dccb37d96448edf72b7d042b06833d4ead24
ToppCell	mLN-Macrophage-LYVE1_Macrophage\|Macrophage / Region, Cell class and subclass	HNRNPDL PLOD3 RTN3 TTC3 AKAP9 AHNAK HERC1	3.37e-06	200	140	7	e3c15e0e1c2602b0cc9ab8cc50c978d265350c94
ToppCell	LPS_only-Epithelial_alveolar-AT_1\|LPS_only / Treatment groups by lineage, cell group, cell type	ABCA3 ANXA1 SYNE2 KIFC3 ATP1A1 PATJ TJP3	3.37e-06	200	140	7	9a6ae40f3e17cd44ee5fd73260713b920aa2ea15
ToppCell	facs-Brain_Myeloid-Cortex_-18m-Myeloid-macrophage\|Brain_Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PLA2G7 ANXA1 CAPN1 XDH AHNAK EHD1	1.01e-05	156	140	6	2ba838bc864c2c1767bcab7bb4d790af96b91387
ToppCell	myeloid-Monocyte-CD14+_Monocyte\|Monocyte / Lineage, cell class and subclass	DSC2 ANXA1 PSMD12 NIBAN2 JARID2 VNN2	1.59e-05	169	140	6	7c3144a6599787f28662f5b22b8e45f4a115aeda
ToppCell	3'_v3-lymph-node_spleen-Lymphocytic_T_CD4-T_CD4/CD8\|lymph-node_spleen / Manually curated celltypes from each tissue	ACAP1 CHD1 CHD2 AKAP9 SYNE2 HERC1	1.70e-05	171	140	6	2e9a20f8980b78325c52065a9c14ab3656267c05
ToppCell	Primary_Motor_Cortex_(M1)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_D_(IT_RORB_THEMIS_LINC00507)_3-Exc_L3-5_THEMIS_ELOF1\|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	PLA2G7 COL19A1 PDGFRB ANXA1 LAMA4 RORB	2.00e-05	176	140	6	78306517b1e52411a2ba72f141efea4d12c09f25
ToppCell	ASK454-Endothelial-Lymphatic\|ASK454 / Donor, Lineage and Cell class of Lung cells from Dropseq	DNAH3 EML6 LAMA4 MMRN1 TXNDC16 KIF17	2.20e-05	179	140	6	fd84a79f76a01c0377dff5b20016b004d369f96f
ToppCell	10x5'-Liver-Lymphocytic_T_CD4-T_CD4/CD8\|Liver / Manually curated celltypes from each tissue	ACAP1 CHD2 OSBPL3 AHNAK SYNE2 HERC1	2.34e-05	181	140	6	f2315414e714ac86211546a935660c4be6e85f1b
ToppCell	3'-Pediatric_IBD-SmallIntestine-Epithelial-Tuft-related\|Pediatric_IBD / Celltypes from developing, pediatric, Crohn's, & adult GI tract	ERBB3 DSC2 FRMD1 SPATS2L PLCG2 ST18	2.49e-05	183	140	6	263937906ddabc798bbe60f0da28ba859a5c72e2
ToppCell	LPS_only-Epithelial_alveolar-AT_1-Differentiating_AT1\|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	ABCA3 NIBAN2 SYNE2 KIFC3 PATJ TJP3	2.57e-05	184	140	6	42ce855b4f8475a8298192feec785bdc69bc5bb0
ToppCell	LPS-IL1RA-Epithelial_alveolar-AT_1\|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	ABCA3 ANXA1 OSBPL3 KIFC3 PATJ TJP3	2.57e-05	184	140	6	cdf6f1c6cce97a7effa0c55959652e2c0b6992b3
ToppCell	Somatosensory_Cortex_(S1)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_C_(IT_L4_RORB)-Exc_L3-4_RORB_RPS3P6\|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	PDGFRB ANXA1 LAMA4 LIN7A RORB CEP152	2.65e-05	185	140	6	10da5c2a92bfb3248d3f6f94a0933996326cf590
ToppCell	390C-Lymphocytic-NK_cells-NK_cell_A2\|390C / Donor, Lineage, Cell class and subclass (all cells)	APAF1 FBXO5 TXNDC16 SASS6 UBE2Q2	2.67e-05	111	140	5	dfbdeadad321392d359e6fb7112b28b043a4b874
ToppCell	PBMC_fresh-frozen-Mild-Moderate_convalescent_d36-51-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD4_c07-AHNAK\|Mild-Moderate_convalescent_d36-51 / Compartment, severity and other cell annotations on 10x 3' data (130k)	ANXA1 CFAP36 LDHA AHNAK SYNE2 PATJ	2.90e-05	188	140	6	3e3055dacc05a932f2beb114babf1dc76994e1af
ToppCell	11.5-Airway-Mesenchymal-Pericyte\|Airway / Age, Tissue, Lineage and Cell class	BHLHE41 PDGFRB ADGRB1 HMCN1 CHRD TNNT3	2.90e-05	188	140	6	916971d8660fd20f616346953874e89d2cd13e88
ToppCell	LV-14._Fibroblast_III\|World / Chamber and Cluster_Paper	PDGFRB CHD1 TTC3 AKAP12 JARID2 NCOR2	2.99e-05	189	140	6	3922135d1f6fc768d71ba3b465585fead6ea68a8
ToppCell	LPS-IL1RA-Epithelial_alveolar-AT_1-AT2_Progenitor\|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	ABCA3 ANXA1 OSBPL3 KIFC3 PATJ TJP3	2.99e-05	189	140	6	5f883ef4cc0383142d538ae61f4fb40dfdb8ef18
ToppCell	PCW_07-8.5-Endothelial-Endothelial_mature-endo_bronchial_(8)\|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung	ANXA1 BHLHE40 MMRN1 SHE PLCG2 KIF17	2.99e-05	189	140	6	4bc3826e0515b3cf2e2ef72a7b2cf9c32ade1812
ToppCell	control-Myeloid-CD14_Monocytes_2\|Myeloid / Cohort 2 (Rhapsody WB + PBMC) with disease condition, lineage and cell classs	RFK ANXA1 SQLE NIBAN2 LDHA AHNAK	2.99e-05	189	140	6	7f78b5bb8195f99b18082cbb612e9199b7a1538c
ToppCell	3'-Adult-LargeIntestine-Endothelial-lymphatic_endothelial-LEC6_(ADAMTS4+)\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	ANXA1 RPS6KA2 LAMA4 AKAP12 MMRN1 KIF17	3.26e-05	192	140	6	ee9a23a4f00424a50bd7907cf3b12dc50027877e
ToppCell	15-Airway-Endothelial\|Airway / Age, Tissue, Lineage and Cell class	RPS6KA2 BHLHE40 MMRN1 SHE PLCG2 KIF17	3.46e-05	194	140	6	ac0e48b0c09a7f57d30dff321b0c30a4c5e16ad9
ToppCell	CTRL-Myeloid-Monocyte_Macrophage\|Myeloid / Disease state, Lineage and Cell class	PLA2G7 PALD1 NIBAN2 NRIP3 JARID2 ST18	3.46e-05	194	140	6	73459ee062ae1f1a3bb9719dc0b89aae10600e22
ToppCell	15-Airway-Endothelial-Endothelial\|Airway / Age, Tissue, Lineage and Cell class	RPS6KA2 BHLHE40 MMRN1 SHE PLCG2 KIF17	3.46e-05	194	140	6	f3851337a2d17f4acef2cd812a766eb0b503748b
ToppCell	tumor_Lung\|World / Location, Cell class and cell subclass	PLA2G7 ANXA1 BHLHE40 S100A2 DUSP10 MMP14	3.46e-05	194	140	6	7e6b8a30f8d08252ad3f1df826d6f7c0ba997c2c
ToppCell	COVID_non-vent-Lymphocytic-T_cell\|COVID_non-vent / Disease condition, Lineage, Cell class and subclass	ACAP1 OBSCN CHD2 TTC3 SYNE2 PATJ	3.56e-05	195	140	6	4bdedd924564a260841a9153604026b57487c83d
ToppCell	3'-Adult-LargeIntestine-Endothelial-lymphatic_endothelial\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	ANXA1 RPS6KA2 LAMA4 AKAP12 MMRN1 KIF17	3.56e-05	195	140	6	36d4a11bc77a4cc97a22525c78ef8359f4a3ca66
ToppCell	(5)_Epi_stratified\|World / Oesophagus cell shreds on cell class (v1) and cell subclass (v1)	DSC2 ANXA1 SQLE BHLHE40 S100A2 AHNAK	3.76e-05	197	140	6	2b35bcff0637cd5af9bec1ac6bca2b59a92e2f64
ToppCell	LPS_IL1RA-Epithelial_alveolar-AT_1-Differentiating_AT2\|LPS_IL1RA / Treatment groups by lineage, cell group, cell type	ABCA3 OSBPL3 SYNE2 KIFC3 PATJ TJP3	3.76e-05	197	140	6	b94645d57efe8d9e032bffb8c89af1f425c6421e
ToppCell	3'-GW_trimst-1-LargeIntestine-Endothelial\|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	ANXA1 RPS6KA2 BHLHE40 MMRN1 SHE KIF17	3.76e-05	197	140	6	4623cce5eca0c26c8103950e9874b40918226aa5
ToppCell	10x_3'_v3-tissue-resident_(10x_3'_v3)-myeloid-myeloid_monocytic-leukocyte\|tissue-resident_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type	ACAP1 S100A2 NBAS AHNAK SYNE2 PLEC	3.76e-05	197	140	6	d968d7d5608b175bb567ea3a315bf473ec3be459
ToppCell	3'_v3-Lung-Myeloid_Mac-Intermediate_macrophages\|Lung / Manually curated celltypes from each tissue	PLA2G7 NIBAN2 NRIP3 JARID2 EHD1 KIFC3	3.76e-05	197	140	6	bcb4dc17dae705bd84ea6a2842d6b107562baeb7
ToppCell	H1299-infected-SARSCoV2\|infected / Cell line, Condition and Strain	TBRG4 CHD2 AKAP9 AHNAK GNL2 CEP152	3.76e-05	197	140	6	0fa3e4cf93e77d78b1f97b906c5b13ca741ae17e
ToppCell	mLN-T_cell-Th17\|mLN / Region, Cell class and subclass	ANXA1 FLG2 NRIP3 BHLHE40 AHNAK DUSP10	3.87e-05	198	140	6	04905f62941b193864704a10ad692faf777fa51d
ToppCell	mLN-(1)_T_cell-(13)_Th17\|mLN / shred on region, Cell_type, and subtype	ANXA1 FLG2 NRIP3 BHLHE40 AHNAK DUSP10	3.87e-05	198	140	6	c575e9aeee4e034e8c4d171fe754403652343731
ToppCell	mLN-T_cell-Th17\|T_cell / Region, Cell class and subclass	ANXA1 FLG2 NRIP3 BHLHE40 AHNAK DUSP10	3.87e-05	198	140	6	efdc9515dd9fb20ef9c8ddc106d88cbdde7d6ea2
ToppCell	(5)_Epithelial_cells-(5)_Epi_stratified\|(5)_Epithelial_cells / Oesophagus cell shreds on cell class (v1) and cell subclass (v1)	DSC2 ANXA1 SQLE BHLHE40 S100A2 AHNAK	3.87e-05	198	140	6	b3aec042912ce53bd86e86b6761a0604d9998ab5
ToppCell	(5)_Epithelial_cells\|World / Oesophagus cell shreds on cell class (v1) and cell subclass (v1)	DSC2 ANXA1 CAPN1 LDHA S100A2 AHNAK	3.87e-05	198	140	6	6dd7dd356d55c03bb14fa47cc69764403c3f48d4
ToppCell	3'-GW_trimst-1-LargeIntestine-Endothelial-blood_vessel_EC\|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	ANXA1 RPS6KA2 BHLHE40 MMRN1 SHE KIF17	3.87e-05	198	140	6	96d46e73f968391000ecd14c787efb93c79f96ec
ToppCell	Non-neuronal-Postmitotic-Endothelial\|World / Primary Cells by Cluster	PALD1 PDGFRB ANXA1 LAMA4 BHLHE40 AHNAK	3.98e-05	199	140	6	b9763ac9857a60db6f1f104fe1e9ea2266cf931b
ToppCell	moderate-Myeloid-Non-resident_Macrophage\|Myeloid / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls	PLA2G7 NIBAN2 NRIP3 AHNAK PLEC ATP1A1	3.98e-05	199	140	6	3895e367a33ac0316f96a64c07574de99684f4b7
ToppCell	Non-neuronal-Postmitotic-Endothelial-Endothelial-24\|World / Primary Cells by Cluster	PALD1 PDGFRB ANXA1 LAMA4 BHLHE40 AHNAK	3.98e-05	199	140	6	0b4edf3e359749827ef978a77b5267ddde732d71
ToppCell	(02)_MMP9/10+-(2)_GFP_FOXI1\|(02)_MMP9/10+ / shred by cell type by condition	RFK RTN3 TTC3 SPATS2L AKAP9 SYNE2	3.98e-05	199	140	6	18a7f9ced4364f45b184bd529f32ef02c27779d3
ToppCell	10x5'v1-week_14-16-Myeloid_neutrophil-granulo-neutrophil-myelocyte\|week_14-16 / cell types per 3 fetal stages;per 3',per 5'	ACAP1 ANXA1 RTN3 SYNE2 EHD1 SLC26A6	3.98e-05	199	140	6	a1635a52318be0423f8e4fc03d971c28cd22b57e
ToppCell	Non-neuronal-Postmitotic-Endothelial-Endothelial\|World / Primary Cells by Cluster	PALD1 PDGFRB ANXA1 LAMA4 BHLHE40 AHNAK	3.98e-05	199	140	6	9e01eee126247a0696c71b019f855a8a41a0ede3
ToppCell	LPS_IL1RA-Epithelial_alveolar-AT_1\|LPS_IL1RA / Treatment groups by lineage, cell group, cell type	ABCA3 OSBPL3 SYNE2 KIFC3 PATJ TJP3	3.98e-05	199	140	6	a270630626df614f8605abddb7dee7c4d74f6149
ToppCell	human_hepatoblastoma-Tumor_cells-T9\|Tumor_cells / Sample and Cell Type and Tumor Cluster (all cells)	GLRX3 NOC3L CHD1 PLCG2 FGD6 UBE2Q2	3.98e-05	199	140	6	e9c83555d2197b740797a9f33b64f8f7a7ba1ee2
ToppCell	(05)_Secretory-(2)_GFP_FOXI1\|(05)_Secretory / shred by cell type by condition	PSMD12 TTC3 AKAP9 MAP4K5 SYNE2 EIF3M	3.98e-05	199	140	6	d72d87e1e530ed894c0ad5e7b5b2b1d6b59fa098
ToppCell	LPS_anti-TNF-Mesenchymal_fibroblastic-Fibroblasts-MatrixFB\|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type	PDGFRB LAMA4 NRIP3 AKAP12 AKAP9 MMP14	4.10e-05	200	140	6	9b0916d8d07ac2bf1739f7be5296bf77ffee6094
ToppCell	LPS_only-Epithelial_alveolar-AT_1-Differentiating_AT1\|LPS_only / Treatment groups by lineage, cell group, cell type	ABCA3 OSBPL3 SYNE2 KIFC3 PATJ TJP3	4.10e-05	200	140	6	2dadf317a42a7e27cc1fac74f91b806c93a57108
ToppCell	Brain_organoid-organoid_Tanaka_cellReport-10w-Neuroepithelial\|10w / Sample Type, Dataset, Time_group, and Cell type.	DSC2 ANXA1 LAMA4 AHNAK MMP14 TNNT3	4.10e-05	200	140	6	ff0b2675c68e9fc1fa16b3276431f199f3642eac
ToppCell	mild\|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class	CHD1 CHD2 AKAP9 AHNAK SYNE2 PLCG2	4.10e-05	200	140	6	12f1685ce8f218433068e090c9d839cd5a1910bf
ToppCell	Brain_organoid-organoid_Tanaka_cellReport-10w-Neuroepithelial-Proteoglycan-expressing_cell\|10w / Sample Type, Dataset, Time_group, and Cell type.	DSC2 ANXA1 LAMA4 AHNAK MMP14 TNNT3	4.10e-05	200	140	6	07d2133c85e0a4eb8bef653ee15ecd0f1b2bbd44
ToppCell	LPS_IL1RA_TNF-Mesenchymal_myocytic-Myofibroblastic-Myofibroblast\|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type	DOCK3 LAMA4 LIN7A SPATS2L MAP4K5 CPLANE1	4.10e-05	200	140	6	dcdaec3ca3a3024dc1b8788c417003f84c2bffdc
ToppCell	severe-immature_Neutrophil\|severe / Cohort 1 (10x PBMC) with disease condition, cell group and cell class	ANXA1 APAF1 RTN3 LIN7A PLCG2 POLQ	4.10e-05	200	140	6	a9b87accdaa6956116ab82427e1330e8f007ef94
ToppCell	droplet-Fat-Gat-18m-Mesenchymal-nan\|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PDGFRB FBXO5 FKTN MTOR KDM8	6.12e-05	132	140	5	4152529611eeacf0c547e2a134d5b98c45426b13
ToppCell	LPS-IL1RA+antiTNF-Epithelial_alveolar-AT_1-Differentiating_AT2\|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	ABCA3 NIBAN2 FKTN KIFC3 PATJ	6.34e-05	133	140	5	5bf5e654653e2c340891f51e3f2a30441b7b6b2b
ToppCell	3'_v3-blood-Lymphocytic_T_CD4-T_CD4/CD8\|blood / Manually curated celltypes from each tissue	CHD2 AKAP9 SYNE2 PLCG2 HERC1	6.81e-05	135	140	5	ae2d3a42e567b5bade304c0caa497eb725be3565
ToppCell	renal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell-Distal_Convoluted_Tubule_Cell_Type_2\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	NEURL2 IFT172 HMCN1 TJP2 VDR	7.30e-05	137	140	5	85b3a98039c1f68addad0334aa5b2584f6045aaa
ToppCell	3'_v3-Lung-Lymphocytic_T_CD4-T_CD4/CD8\|Lung / Manually curated celltypes from each tissue	ACAP1 OBSCN CHD2 SYNE2 PATJ	1.15e-04	151	140	5	999c11d19b61d6b130ad5e623afa83cbdfe13cdd
ToppCell	facs-Brain_Myeloid-Cerebellum_-18m-Myeloid-macrophage\|Brain_Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PLA2G7 ANXA1 S100A2 AHNAK EHD1	1.15e-04	151	140	5	3105b8c0c401faa92e1ab8223d435b21ed45c5b7
ToppCell	facs-Brain_Myeloid-Cortex-3m-Myeloid-macrophage\|Brain_Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PLA2G7 ERBB3 XDH SPATS2L AHCY	1.23e-04	153	140	5	0ef7c45cdd854c79e527006034029767f8e108b2
ToppCell	facs-Brain_Myeloid-Cortex-24m-Myeloid-macrophage\|Brain_Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PLA2G7 ANXA1 XDH BHLHE40 AHNAK	1.27e-04	154	140	5	1e088b0d4a44267f46a9b643f46a1aba784686b1
ToppCell	10x5'-Liver-Lymphocytic_T_CD4/8-lo-Trm_Tgd\|Liver / Manually curated celltypes from each tissue	ABCA3 RTN4IP1 POGLUT1 CCDC87 XRRA1	1.27e-04	154	140	5	c6308074468235c88ef4ea43ab155d9f86cbf261
ToppCell	5'-Adult-Appendix-Hematopoietic-B_cells-Cycling_B_cell\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	EML6 IGF2BP3 SYNE2 PLCG2 FGD6	1.34e-04	156	140	5	203ef22eb76bd2b829b027c30af0557080f4006c
ToppCell	severe_COVID-19-MAIT\|severe_COVID-19 / disease group, cell group and cell class (v2)	ERBB3 BHLHE40 SYNE2 DUSP10 SENP7	1.39e-04	157	140	5	175f637e9707836bd63b5c2ccc9d4eb601c05b9e
ToppCell	facs-Spleen-nan-18m-Lymphocytic-NK_cell\|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ANXA1 STYK1 SHC4 OSBPL3 AHNAK	1.39e-04	157	140	5	a84377028c661f8f3ecae0f6082abdd859faf0c8
ToppCell	facs-Brain_Myeloid-Striatum_-18m-Myeloid-macrophage\|Brain_Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PLA2G7 ANXA1 XDH EHD1 PLEC	1.39e-04	157	140	5	9d4308312301cb922f156a7b6aededc9e1c62807
ToppCell	(03)_Secretory-(3)_72hpi\|(03)_Secretory / shred by cell type and Timepoint	DSC2 ANXA1 STYK1 AKAP12 MMP14	1.43e-04	158	140	5	20563d03183b63aafc9c389f3f03781140702249
ToppCell	wk_20-22-Hematologic_Lymphocytic-T_&_ILC-T_entry\|wk_20-22 / Celltypes from embryonic and fetal-stage human lung	ACAP1 RANBP6 CHD1 JARID2 RORB	1.60e-04	162	140	5	a27750117e7f16a0bd07cc5f58a56becb39e800b
ToppCell	facs-Marrow-T-cells-3m-Lymphocytic-NK_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	STYK1 BHLHE40 OSBPL3 AHNAK KIFC3	1.70e-04	164	140	5	9fed5df40f50bde35db8bf89c291cbdc0e104112
ToppCell	facs-Marrow-T-cells-3m-Lymphocytic-NK_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	STYK1 BHLHE40 OSBPL3 AHNAK KIFC3	1.70e-04	164	140	5	e712d6b89461f741dbd773ba9a27ecaddf97cbaa
ToppCell	facs-Spleen-nan-3m-Lymphocytic-NK_cell\|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ANXA1 STYK1 BHLHE40 OSBPL3 AHNAK	1.70e-04	164	140	5	a187bd5beca017ef657ef07c006e7f94ea3b911b
ToppCell	PND01-Immune-Immune_Lymphocytic_T/NK-Lymphocytic_B-B-B_prolif\|PND01 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	BHLHE41 ACAP1 RTN4IP1 FBXO5 POLQ	1.75e-04	165	140	5	66f0364098d82629aa2ec1dfe0c5ad23de7c2c12
ToppCell	facs-Liver-Liver_non-hepato/SCs-18m-Myeloid-neutrophil\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PLA2G7 ANXA1 GSDMA GRIP2 TNNT3	1.75e-04	165	140	5	4fe7c3c9370a556cf4e308a2e723b4b907a6cc25
ToppCell	facs-Brain_Myeloid-Hippocampus-24m-Myeloid-macrophage\|Brain_Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PLA2G7 ACAP1 ANXA1 XDH AHNAK	1.75e-04	165	140	5	ab6ed7e30096c418e7be2d5eec33feeddd1387d9
ToppCell	droplet-Spleen-SPLEEN-30m-Lymphocytic-NK_cell\|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DSC2 STYK1 OSBPL3 AHNAK KIFC3	1.75e-04	165	140	5	e24621c8d4dbafb407033d832fe9337f13feae34
ToppCell	droplet-Spleen-SPLEEN-1m-Lymphocytic-NK_cell\|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	COL19A1 STYK1 OSBPL3 AHNAK KIFC3	1.75e-04	165	140	5	8741df8066a44c841752a99ad306d26ea68f5344
ToppCell	normal_Lung-Myeloid_cells-CD163+CD14+_DCs\|Myeloid_cells / Location, Cell class and cell subclass	RALGDS ACAP1 APAF1 BHLHE40 JARID2	1.80e-04	166	140	5	07b498eb341abec02a3ccaae320bdbb5cd6883c5
ToppCell	Brain_organoid-organoid_Kanton_Nature-Organoid-4M-Stem_cells-neuroepithelial-like_cells\|Organoid-4M / Sample Type, Dataset, Time_group, and Cell type.	RALGDS PLOD3 OBSCN SHC4 DUSP10	1.85e-04	167	140	5	e488d9c7cf4355959e3833de3bd496c13fc11b1b
ToppCell	368C-Endothelial_cells-Endothelial-F_(Lymphatics)\|368C / Donor, Lineage, Cell class and subclass (all cells)	PALD1 AKAP12 MMRN1 SHE FGD6	1.90e-04	168	140	5	a74c8a9e3299183fba31ce3053ef325b5dbcd104
Drug	Metronidazole [443-48-1]; Down 200; 23.4uM; PC3; HG-U133A	HNRNPDL TBRG4 VWA8 RANBP6 SRBD1 BHLHE40 JARID2 COMMD8 STK38L	3.58e-06	196	140	9	1921_DN
Drug	Amoxapine [14028-44-5]; Down 200; 12.8uM; PC3; HG-U133A	RFK FBXO5 MAP4K5 OSBPL3 EHD1 TRMT13 STK38L EIF3M MMUT	3.74e-06	197	140	9	1931_DN
Disease	Malignant neoplasm of breast	ACAP1 ERBB3 ABCA3 COL19A1 OBSCN XDH TTC3 AKAP12 CHRND KMT2D AKAP9 FKTN MTOR SYNE2 MMP14 EIF3M VDR	1.06e-05	1074	137	17	C0006142
Disease	factor XI measurement, fibrinogen measurement, tissue plasminogen activator measurement, factor VII measurement	MAP4K5 AHCY FNIP1 PLEC	1.35e-04	56	137	4	EFO_0004619, EFO_0004623, EFO_0004694, EFO_0004791
Disease	Limb-girdle muscular dystrophy	HNRNPDL FKTN PLEC	2.35e-04	26	137	3	cv:C0686353
Disease	acute kidney failure (implicated_via_orthology)	ANXA1 XDH MTOR	2.64e-04	27	137	3	DOID:3021 (implicated_via_orthology)
Disease	cancer (implicated_via_orthology)	ACAP1 RFK SQLE RANBP6 PSMD12 FRMD1 MTOR	2.66e-04	268	137	7	DOID:162 (implicated_via_orthology)
Disease	Malignant Neoplasms	ERBB3 TRPV1 CAPN1 MTOR VDR	3.36e-04	128	137	5	C0006826
Disease	Sarcomatoid Renal Cell Carcinoma	DNHD1 APAF1 MTOR AHNAK SYNE2	3.36e-04	128	137	5	C1266043
Disease	Chromophobe Renal Cell Carcinoma	DNHD1 APAF1 MTOR AHNAK SYNE2	3.36e-04	128	137	5	C1266042
Disease	Collecting Duct Carcinoma of the Kidney	DNHD1 APAF1 MTOR AHNAK SYNE2	3.36e-04	128	137	5	C1266044
Disease	Papillary Renal Cell Carcinoma	DNHD1 APAF1 MTOR AHNAK SYNE2	3.36e-04	128	137	5	C1306837
Disease	Renal Cell Carcinoma	DNHD1 APAF1 MTOR AHNAK SYNE2	3.36e-04	128	137	5	C0007134
Disease	Muscular Dystrophies, Limb-Girdle	HNRNPDL FKTN PLEC	4.40e-04	32	137	3	C0686353
Disease	prostate cancer (implicated_via_orthology)	PDGFRB CHD1 CHD2	4.82e-04	33	137	3	DOID:10283 (implicated_via_orthology)
Disease	Conventional (Clear Cell) Renal Cell Carcinoma	DNHD1 APAF1 MTOR AHNAK SYNE2	6.52e-04	148	137	5	C0279702
Disease	Nephronophthisis	IFT172 INVS	7.54e-04	9	137	2	cv:C0687120
Disease	cathepsin F measurement	MAP4K5 CCDC87	7.54e-04	9	137	2	EFO_0022038
Disease	serum alanine aminotransferase measurement	ERBB3 L2HGDH XDH JARID2 MAP4K5 AHNAK AHCY TJP2 PATJ SLC33A1 SENP7 TJP3	7.60e-04	869	137	12	EFO_0004735
Disease	dilated cardiomyopathy (is_marker_for)	IL13RA2 OBSCN MMP14	7.92e-04	39	137	3	DOID:12930 (is_marker_for)
Disease	nevus count, cutaneous melanoma	AKAP12 TASOR2 JARID2 SYNE2	8.69e-04	91	137	4	EFO_0000389, EFO_0004632
Disease	level of Ceramide (d40:1) in blood serum	MAP4K5 SYNE2	1.15e-03	11	137	2	OBA_2045185
Disease	Cardiomyopathy	DSC2 LAMA4 FKTN	1.37e-03	47	137	3	cv:C0878544
Disease	cataract (biomarker_via_orthology)	ANXA1 XDH	1.61e-03	13	137	2	DOID:83 (biomarker_via_orthology)
Disease	non-alcoholic fatty liver disease, type 2 diabetes mellitus	SHC4 TJP2 PLCG2 ST18	1.76e-03	110	137	4	EFO_0003095, MONDO_0005148
Disease	breast cancer (is_marker_for)	PDGFRB NCOR2 KMT2D KDM8 VDR	1.76e-03	185	137	5	DOID:1612 (is_marker_for)
Disease	episodic memory	EML6 NBAS RORB	1.83e-03	52	137	3	EFO_0004333
Disease	chronic kidney disease (is_implicated_in)	XDH AKAP12	1.88e-03	14	137	2	DOID:784 (is_implicated_in)
Disease	Autosomal recessive limb-girdle muscular dystrophy	FKTN PLEC	1.88e-03	14	137	2	cv:C2931907
Disease	Metastatic melanoma	RPS6KA2 STK38 MTOR	2.04e-03	54	137	3	C0278883
Disease	Neoplasm of uncertain or unknown behavior of bladder	ERBB3 MTOR	2.16e-03	15	137	2	C0496930
Disease	Benign neoplasm of bladder	ERBB3 MTOR	2.16e-03	15	137	2	C0154017
Disease	Carcinoma in situ of bladder	ERBB3 MTOR	2.16e-03	15	137	2	C0154091
Disease	Autosomal recessive primary microcephaly	SASS6 CEP152	2.16e-03	15	137	2	cv:C3711387
Disease	diacylglycerol 44:7 measurement	IFT172 MAP4K5	2.46e-03	16	137	2	EFO_0020069
Disease	Inborn Errors of Metabolism	PLA2G7 MMUT	2.78e-03	17	137	2	C0025521
Disease	cutaneous melanoma, hair color	AKAP12 AHNAK SYNE2	3.03e-03	62	137	3	EFO_0000389, EFO_0003924
Disease	Carcinoma of bladder	ERBB3 MTOR	3.12e-03	18	137	2	C0699885
Disease	oral squamous cell carcinoma (is_marker_for)	BHLHE41 IL13RA2 KMT2D	3.17e-03	63	137	3	DOID:0050866 (is_marker_for)
Disease	Cardiomyopathies	DSC2 LAMA4 LDHA FKTN	3.22e-03	130	137	4	C0878544
Disease	laryngeal squamous cell carcinoma (is_marker_for)	ERBB3 XDH	3.47e-03	19	137	2	DOID:2876 (is_marker_for)
Disease	platelet measurement	EML6 STK38 MAP4K5 CHRD PLCG2 PLEC	3.61e-03	315	137	6	EFO_0005036
Disease	breast carcinoma (is_marker_for)	PDGFRB KMT2D MMP14	3.62e-03	66	137	3	DOID:3459 (is_marker_for)
Disease	Benign Neoplasm	TRPV1 CAPN1 VDR	3.94e-03	68	137	3	C0086692
Disease	Neoplasms	TRPV1 CAPN1 VDR	3.94e-03	68	137	3	C0027651
Disease	Bladder Neoplasm	ERBB3 TRPV1 KMT2D MTOR	4.19e-03	140	137	4	C0005695
Disease	hypertension (biomarker_via_orthology)	PDGFRB ANXA1 XDH LDHA TJP2	4.24e-03	227	137	5	DOID:10763 (biomarker_via_orthology)
Disease	esophagus adenocarcinoma (is_implicated_in)	MMP14 VDR	4.24e-03	21	137	2	DOID:4914 (is_implicated_in)
Disease	Malignant neoplasm of urinary bladder	ERBB3 TRPV1 KMT2D MTOR	4.30e-03	141	137	4	C0005684
Disease	cardiomyopathy (implicated_via_orthology)	ERBB3 XDH TNNT3	4.44e-03	71	137	3	DOID:0050700 (implicated_via_orthology)

Protein segments in the cluster

Peptide	Gene	Start	Entry
TKAGHSLELIEPLIK	VDR	301	P11473
TGLKLVEEGVPKEHL	SLC33A1	331	O00400
VEEGVPKEHLALLAV	SLC33A1	336	O00400
KAKTELVGPAHLIHE	APAF1	511	O14727
EPHGLTNKKLEEVEL	ERBB3	991	P21860
GVKKLFLETLPELLH	CHRND	346	Q07001
PLSKELGEHGKEILL	AKAP9	1516	Q99996
DHLSKDKPELEVVLT	AKAP9	2456	Q99996
ELVHPALERSLKKLG	AKR1C8	96	Q5T2L2
ILPGKELEEKIHSLQ	CEP152	921	O94986
HLPGALAEKRLSKVE	ASCL5	181	Q7RTU5
LPEHLKLTTLGHLEK	BHLHE41	71	Q9C0J9
PSLPEEEKLKLAHAK	ADGRB1	1256	O14514
PAGAHLVLEEKSSEK	AKAP12	1446	Q02952
KDLLPEHLKLTTLGH	BHLHE40	76	O14503
QKDLKIPGLEHASIE	CFAP36	241	Q96G28
ALDKGHEVTLEALPK	GSDMA	306	Q96QA5
AEPEDLVAGIKIKHL	ABCA3	521	Q99758
LDLHLKSPKAKGEVD	AHNAK	2391	Q09666
LPAIHVEGLDIKAKA	AHNAK	5126	Q09666
RHVLLKQKELGGEEP	ACAP1	241	Q15027
DSELIKLHLILKAPG	DNHD1	3296	Q96M86
LGEPHKILSLQKHLE	CCDC87	671	Q9NVE4
DLLPIKDGKLVFVHS	CAPN1	166	P07384
DLSLTHKILPDDPDK	CHD1	1281	O14646
TLHVPSKLDAEKLVG	DSC2	36	Q02487
DLNKGIEAKIHTLLP	IL13RA2	96	Q14627
KHIKELGRGLPTDKI	MMP14	401	P50281
TLKEKIHKGIPLEEL	RBM44	666	Q6ZP01
EKIHKDHLIGIGIAP	IREB2	876	P48200
LELKEHKLDGKLIDP	HNRNPDL	206	O14979
LLHQELGKGPTKEEL	NIBAN2	451	Q96TA1
LPDGHRVKKEVDAAL	PALD1	716	Q9ULE6
LKTLHPDLGTDKDKE	LDHA	211	P00338
PLDETLKKALTGHLE	ANXA1	91	P04083
KDTLGKPAAKDVHLV	POGLUT1	246	Q8NBL1
DPGLREKLSLNLDHK	PLOD3	201	O60568
LTHDKGLPKHLEELD	NCOR2	2061	Q9Y618
GLPKHLEELDKSHLE	NCOR2	2066	Q9Y618
GELKELLEKELHPVL	FLG2	31	Q5D862
KIKSPEDHIGAVLER	GNL2	386	Q13823
LEKLQESGEVPVHKL	LIN7A	36	O14910
HSLDPGDIRDELKKL	GPR179	671	Q6PRD1
HPSLSIGVLEKEKDL	L2HGDH	71	Q9H9P8
KIDRLDGAHAPELTK	GLRX3	96	O76003
KPIKELEVKQTHLEG	MMRN1	476	Q13201
ILLHGKEQPLDEELK	ATP1A1	521	P05023
DHLLTLKPVKFLEGE	EIF3M	221	Q7L2H7
LKPVKFLEGELIHDL	EIF3M	226	Q7L2H7
KEPLEKGGIVLIDAH	HERC1	3611	Q15751
LPHSKEDLKLDLGEK	KDM8	26	Q8N371
KKARADHGLIPDVKL	KDM8	166	Q8N371
PLHIVLESLKREGKE	DUSP10	251	Q9Y6W6
ESDPLHKELLEKLVL	PDE12	406	Q6L8Q7
IIIKHKKLGPRGDVD	PLCG2	451	P16885
LVHRISGDKKLEEIP	PSMD12	286	O00232
SVLLPLVAKEGKLHL	NUDT7	41	P0C024
LSLHLDVKENGEVKP	COMMD8	141	Q9NX08
RLAIDGLHLPKELKD	NEURL2	266	Q9BR09
VSELLEKHGLEKPIS	NBAS	1046	A2RRP1
ALSGKIELHGKPIEV	IGF2BP3	56	O00425
ILDIDHGKPVKNALD	PLA2G7	236	Q13093
HPLIKAKGVEILDEG	HMCN1	2331	Q96RW7
AVAEAKGHPALEKLR	IFT172	726	Q9UG01
RKEEPLAAKEALGHL	OBSCN	5511	Q5VST9
KEVTLHKDGPLGETV	UPF1	166	Q92900
LHKDKKEGRPTVILG	FRMD1	266	Q8N878
EIDLKLLTKVLAPEH	IFT43	151	Q96FT9
KHPGDAEKITQLKEL	DOCK3	1571	Q8IZD9
GDAGHLQLLKVKIEP	CPLANE1	2441	Q9H799
EKVLIHLSPTGKIVD	DNAH3	2341	Q8TD57
KVPRLKEEHGIELSS	CHD2	1351	O14647
SDGKPVDIELHQLKI	COL19A1	216	Q14993
VHSGLKLVKPDDIGR	FBXO5	56	Q9UKT4
ILVPHGDKESSDKKI	FNIP1	911	Q8TF40
PLGATKIDHLDLKTV	POLQ	1381	O75417
KDKETGDIKELHAPL	SQLE	266	Q14534
PLKHKFGKVEDSLEL	FKTN	341	O75072
VKAGTLEKLVEHLVP	RALGDS	116	Q12967
HLVKEIAEDPVDILG	KANSL2	436	Q9H9L4
HGDPAKVVELKNLEL	MECR	51	Q9BV79
KDILLLKTVKAHDGP	EML6	891	Q6ZMW3
EPLIISDIKKGSVAH	GRIP2	581	Q9C0E4
HLIKVKLEGHELPAD	EHD1	506	Q9H4M9
LPKKLDEAVAEAHLG	AHCY	386	P23526
HLSLKLLPGNDVEIK	SASS6	136	Q6UVJ0
LKIDIIKHPNETDGK	DTWD1	91	Q8N5C7
RLSHLLSEKPEDKGL	TBRG4	106	Q969Z0
HTGELAAVKIIKLEP	MAP4K5	41	Q9Y4K4
ELRKDLGFSKLDHPV	OSBPL3	871	Q9H4L5
LVVTLHEKKGDVALP	PDGFRB	156	P09619
GEEHELSPKEISEKL	LAMA4	406	Q16363
KLLIKHDSNIGIPDV	INVS	166	Q9Y283
EKEILEKRKGPLEGH	JARID2	726	Q92833
LLGVDLSKIEKHPEA	MTERF3	161	Q96E29
EKELIHLLPIKDKSG	NOC3L	146	Q8WTT2
LGADTKQKLELKEHP	KIF17	151	Q9P2E2
EILDGVELGEPAHKK	MTOR	2456	P42345
IHKDSADLLPLDGLK	NRIP3	36	Q9NQ35
LHVKIKGEEFPLTLG	RTN4IP1	106	Q8WWV3
QPILAKEGKDHLDLL	RTN3	111	O95197
EEGPVEHKSSEILKL	SENP7	446	Q9BQF6
RDIKPDNLLLDSKGH	STK38	211	Q15208
PGLLSVEEKKKIGHL	TRMT13	416	Q9NUP7
HRDIKPDNLLLDAKG	STK38L	211	Q9Y2H1
RTVIDGLDLLKKEHP	SMG5	886	Q9UPR3
TPAAHLEIKPDELAK	SPATS2L	201	Q9NUQ6
RESPGELISKHKEAL	SYNE2	871	Q8WXH0
VKLGELFHDLPKAVL	SLC26A6	431	Q9BXS9
LLHKGKPVSFELDKV	KIFC3	481	Q9BVG8
KTLHLEPLKALLEGL	PRAMEF2	71	O60811
EHLEELGGILKAKLE	RANBP6	796	O60518
LAELVKIEPKHIGVG	SRBD1	666	Q8N5C6
HKKDLLEVPEIKTEG	ST18	226	O60284
VKDLEPELLRHLAKG	CHRD	611	Q9H2X0
LLLVDPEGKVRTKDH	SHC4	571	Q6S5L8
LKALKEPAGLHEVQD	STYK1	146	Q6J9G0
LTEIHLSPGKFEVLK	VNN2	446	O95498
VDLSHIPLKDPLLFK	UHRF1BP1L	936	A0JNW5
PLHSDLQILKEKEGI	UBE2Q2	251	Q8WVN8
KKLEAGLENHITILP	TXNDC16	721	Q9P2K2
DKHALLDVTPKAVDL	TJP2	786	Q9UDY2
DHNLEDLKTELGKKP	ZNF804B	491	A4D1E1
LPGLEKLLHHVTEEK	RNASEH2B	131	Q5TBB1
LGAKLHPTLKLEELT	TRPV1	316	Q8NER1
ADLPGELHIIELEKD	PATJ	1231	Q8NI35
KKSEVKDLGPLEIHL	FGD6	291	Q6ZV73
HLDDETLAKLIAKIP	RORB	411	Q92753
HVLSELKEVEPKLAA	TTC3	891	P53804
KTIHLPEQLKEDGTL	TEX10	36	Q9NXF1
LDLKAQHPDAKLVVG	XDH	246	P47989
PKGRHKIIILDEADS	RFC2	131	P35250
GDIEEAKKRLELPEH	RFK	121	Q969G6
VKEGVVGPELHHKLL	PLEC	2891	Q15149
VIAEKDKHALLDVTP	TJP3	666	O95049
PLNIDHLGEDKLRDK	TNNT3	196	P45378
KELLHKELPSFVGEK	S100A2	36	P29034
ASLLKNGEPEAELHK	TASOR2	1691	Q5VWN6
PDTHLLKLLKTLEGH	WDR26	386	Q9H7D7
LKPALSDHSEGEKVD	SHE	371	Q5VZ18
DSPLVKAVKLGHILV	VWA8	831	A3KMH1
ELPSSVIHKDDLELK	XRRA1	571	Q6P2D8
EILGFDILLDHKLKP	TTLL13	371	A6NNM8
PLLIEDLLEHEKKEL	KMT2D	3246	O14686
KPENILLDEEGHIKI	RPS6KA2	186	Q15349
AGHKTLVPELIKELN	MMUT	676	P22033
LGPQSVLLEKHEDKS	NEUROD4	176	Q9HD90