Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	aspartic-type endopeptidase activity	ERVK-6 ERVK-7 ERVK-21 ERVK-9 ERVK-10 ERVK-19 ERVK-24 ERVK-8	1.07e-08	37	239	8	GO:0004190
GeneOntologyMolecularFunction	aspartic-type peptidase activity	ERVK-6 ERVK-7 ERVK-21 ERVK-9 ERVK-10 ERVK-19 ERVK-24 ERVK-8	1.34e-08	38	239	8	GO:0070001
GeneOntologyMolecularFunction	RNA stem-loop binding	ERVK-6 LARP6 ERVK-7 ERVK-10 ERVK-8	4.10e-06	21	239	5	GO:0035613
GeneOntologyMolecularFunction	RNA-DNA hybrid ribonuclease activity	ERVK-6 ERVK-7 ERVK-10 ERVK-8	6.18e-06	11	239	4	GO:0004523
GeneOntologyMolecularFunction	RNA-directed DNA polymerase activity	ERVK-6 ERVK-7 ERVK-10 ERVK-8	1.82e-05	14	239	4	GO:0003964
GeneOntologyMolecularFunction	steroid dehydrogenase activity	DHRS1 RDH14 RDH5 SDR42E2 HSD17B6	9.73e-05	39	239	5	GO:0016229
GeneOntologyMolecularFunction	NADH oxidase H202-forming activity	DUOX1 DUOX2	1.43e-04	2	239	2	GO:0106293
GeneOntologyMolecularFunction	phosphatidylinositol kinase activity	PIK3C2A PIK3CD PI4KA ATM	2.43e-04	26	239	4	GO:0052742
GeneOntologyMolecularFunction	1-phosphatidylinositol-3-kinase activity	PIK3C2A PIK3CD ATM	2.60e-04	11	239	3	GO:0016303
GeneOntologyMolecularFunction	transferase activity, transferring phosphorus-containing groups	ERVK-6 ABL1 ABL2 TRPM7 ERVK-7 CHEK1 ERVK-10 MELK PIK3C2A PIK3CD STRADA DBF4 PI4KA BUB1B TAF1 MAP3K8 OAS3 CIT PAPOLG OASL ERVK-8 IRAK3 PRKDC ATM	3.92e-04	938	239	24	GO:0016772
GeneOntologyMolecularFunction	DNA-dependent protein kinase activity	PRKDC ATM	4.25e-04	3	239	2	GO:0004677
GeneOntologyMolecularFunction	histone H2AXS139 kinase activity	PRKDC ATM	4.25e-04	3	239	2	GO:0035979
GeneOntologyMolecularFunction	adenylyltransferase activity	ABL1 OAS3 PAPOLG OASL	4.88e-04	31	239	4	GO:0070566
GeneOntologyMolecularFunction	nucleotidyltransferase activity	ERVK-6 ABL1 ERVK-7 ERVK-10 OAS3 PAPOLG OASL ERVK-8	5.01e-04	152	239	8	GO:0016779
GeneOntologyMolecularFunction	steroid dehydrogenase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor	DHRS1 RDH5 SDR42E2 HSD17B6	6.23e-04	33	239	4	GO:0033764
GeneOntologyMolecularFunction	RNA endonuclease activity, producing 5'-phosphomonoesters	ERVK-6 ERVK-7 ERVK-10 ERVK-8	9.69e-04	37	239	4	GO:0016891
GeneOntologyMolecularFunction	DNA polymerase activity	ERVK-6 ERVK-7 ERVK-10 ERVK-8	1.07e-03	38	239	4	GO:0034061
GeneOntologyMolecularFunction	histone H2AX kinase activity	PRKDC ATM	1.39e-03	5	239	2	GO:0141003
GeneOntologyMolecularFunction	NADPH oxidase H202-forming activity	DUOX1 DUOX2	1.39e-03	5	239	2	GO:0106294
GeneOntologyMolecularFunction	2'-5'-oligoadenylate synthetase activity	OAS3 OASL	1.39e-03	5	239	2	GO:0001730
GeneOntologyMolecularFunction	lipid kinase activity	PIK3C2A PIK3CD PI4KA ATM	1.43e-03	41	239	4	GO:0001727
GeneOntologyBiologicalProcess	homophilic cell adhesion via plasma membrane adhesion molecules	DCHS2 CLSTN3 MYOT PCDHB15 PCDHB14 PCDHB12 PCDHB11 PCDHB10 PCDHB9 PCDHB7 PCDHB3 IGSF11 PCDHB16	3.41e-07	187	242	13	GO:0007156
GeneOntologyBiologicalProcess	DNA integration	ERVK-6 ERVK-7 ERVK-10 ERVK-8	1.22e-05	13	242	4	GO:0015074
GeneOntologyBiologicalProcess	calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules	PCDHB14 PCDHB11 PCDHB10 PCDHB9 PCDHB3 PCDHB16	3.55e-05	53	242	6	GO:0016339
GeneOntologyBiologicalProcess	RNA-templated DNA biosynthetic process	ERVK-6 ERVK-7 ERVK-10 CTC1 RFC1 ERVK-8 ATM	5.46e-05	83	242	7	GO:0006278
Domain	NPIP	NPIPA1 NPIPB3 NPIPB5 NPIPB13 NPIPB6 NPIPA5 NPIPA3 NPIPA2 NPIPA7 NPIPB2	6.90e-17	14	232	10	IPR009443
Domain	Cadherin_C	PCDHB15 PCDHB14 PCDHB12 PCDHB11 PCDHB10 PCDHB9 PCDHB7 PCDHB3 PCDHB16	1.88e-09	42	232	9	IPR032455
Domain	Cadherin_C_2	PCDHB15 PCDHB14 PCDHB12 PCDHB11 PCDHB10 PCDHB9 PCDHB7 PCDHB3 PCDHB16	1.88e-09	42	232	9	PF16492
Domain	Cadherin_2	PCDHB15 PCDHB14 PCDHB12 PCDHB11 PCDHB10 PCDHB9 PCDHB7 PCDHB3 PCDHB16	1.05e-07	65	232	9	PF08266
Domain	Cadherin_N	PCDHB15 PCDHB14 PCDHB12 PCDHB11 PCDHB10 PCDHB9 PCDHB7 PCDHB3 PCDHB16	1.05e-07	65	232	9	IPR013164
Domain	CADHERIN_1	DCHS2 CLSTN3 PCDHB15 PCDHB14 PCDHB12 PCDHB11 PCDHB10 PCDHB9 PCDHB7 PCDHB3 PCDHB16	1.64e-07	113	232	11	PS00232
Domain	Cadherin	DCHS2 CLSTN3 PCDHB15 PCDHB14 PCDHB12 PCDHB11 PCDHB10 PCDHB9 PCDHB7 PCDHB3 PCDHB16	1.64e-07	113	232	11	PF00028
Domain	CADHERIN_2	DCHS2 CLSTN3 PCDHB15 PCDHB14 PCDHB12 PCDHB11 PCDHB10 PCDHB9 PCDHB7 PCDHB3 PCDHB16	1.79e-07	114	232	11	PS50268
Domain	-	DCHS2 CLSTN3 PCDHB15 PCDHB14 PCDHB12 PCDHB11 PCDHB10 PCDHB9 PCDHB7 PCDHB3 PCDHB16	1.79e-07	114	232	11	2.60.40.60
Domain	CA	DCHS2 CLSTN3 PCDHB15 PCDHB14 PCDHB12 PCDHB11 PCDHB10 PCDHB9 PCDHB7 PCDHB3 PCDHB16	1.96e-07	115	232	11	SM00112
Domain	Cadherin-like	DCHS2 CLSTN3 PCDHB15 PCDHB14 PCDHB12 PCDHB11 PCDHB10 PCDHB9 PCDHB7 PCDHB3 PCDHB16	2.14e-07	116	232	11	IPR015919
Domain	Cadherin	DCHS2 CLSTN3 PCDHB15 PCDHB14 PCDHB12 PCDHB11 PCDHB10 PCDHB9 PCDHB7 PCDHB3 PCDHB16	2.55e-07	118	232	11	IPR002126
Domain	PI3/4_kinase_CS	PIK3C2A PIK3CD PI4KA PRKDC ATM	7.69e-07	15	232	5	IPR018936
Domain	Cadherin_CS	DCHS2 PCDHB15 PCDHB14 PCDHB12 PCDHB11 PCDHB10 PCDHB9 PCDHB7 PCDHB3 PCDHB16	1.05e-06	109	232	10	IPR020894
Domain	-	PIK3C2A PIK3CD PI4KA PRKDC ATM	1.11e-06	16	232	5	1.10.1070.11
Domain	PI3Kc	PIK3C2A PIK3CD PI4KA PRKDC ATM	1.11e-06	16	232	5	SM00146
Domain	PI3_PI4_kinase	PIK3C2A PIK3CD PI4KA PRKDC ATM	2.13e-06	18	232	5	PF00454
Domain	PI3_4_KINASE_1	PIK3C2A PIK3CD PI4KA PRKDC ATM	2.13e-06	18	232	5	PS00915
Domain	PI3_4_KINASE_2	PIK3C2A PIK3CD PI4KA PRKDC ATM	2.13e-06	18	232	5	PS00916
Domain	PI3/4_kinase_cat_dom	PIK3C2A PIK3CD PI4KA PRKDC ATM	2.13e-06	18	232	5	IPR000403
Domain	PI3_4_KINASE_3	PIK3C2A PIK3CD PI4KA PRKDC ATM	2.13e-06	18	232	5	PS50290
Domain	PI3Ka	PIK3C2A PIK3CD PI4KA	1.50e-04	9	232	3	PF00613
Domain	PI3Ka	PIK3C2A PIK3CD PI4KA	1.50e-04	9	232	3	SM00145
Domain	-	PIK3C2A PIK3CD PI4KA	1.50e-04	9	232	3	1.25.40.70
Domain	Med13_N	MED13 MED13L	1.54e-04	2	232	2	PF11597
Domain	PIEZO	PIEZO1 PIEZO2	1.54e-04	2	232	2	PF15917
Domain	Mediator_Med13_N_met/fun	MED13 MED13L	1.54e-04	2	232	2	IPR021643
Domain	DUOX1	DUOX1 DUOX2	1.54e-04	2	232	2	IPR029595
Domain	F_actin_bind	ABL1 ABL2	1.54e-04	2	232	2	PF08919
Domain	Piezo	PIEZO1 PIEZO2	1.54e-04	2	232	2	IPR027272
Domain	Piezo_RRas_bdg	PIEZO1 PIEZO2	1.54e-04	2	232	2	PF12166
Domain	F-actin_binding	ABL1 ABL2	1.54e-04	2	232	2	IPR015015
Domain	Med13_C	MED13 MED13L	1.54e-04	2	232	2	PF06333
Domain	NatA_aux_su	NAA16 NAA15	1.54e-04	2	232	2	IPR021183
Domain	NARP1	NAA16 NAA15	1.54e-04	2	232	2	PF12569
Domain	Piezo_RRas-bd_dom	PIEZO1 PIEZO2	1.54e-04	2	232	2	IPR031334
Domain	Mediator_Med13	MED13 MED13L	1.54e-04	2	232	2	IPR009401
Domain	FABD	ABL1 ABL2	1.54e-04	2	232	2	SM00808
Domain	Piezo_dom	PIEZO1 PIEZO2	1.54e-04	2	232	2	IPR031805
Domain	PI_Kinase	PIK3C2A PIK3CD PI4KA	2.13e-04	10	232	3	IPR015433
Domain	PInositide-3_kin_accessory_dom	PIK3C2A PIK3CD PI4KA	2.13e-04	10	232	3	IPR001263
Domain	PIK_HELICAL	PIK3C2A PIK3CD PI4KA	2.13e-04	10	232	3	PS51545
Domain	BACK	KBTBD3 BTBD6 KLHL30 KBTBD6 KLHL12	8.87e-04	60	232	5	SM00875
Domain	OAS1_C	OAS3 OASL	9.07e-04	4	232	2	PF10421
Domain	SHR-BD	VPS13D VPS13B	9.07e-04	4	232	2	IPR009543
Domain	2-5-oligoadenylate_synth_CS	OAS3 OASL	9.07e-04	4	232	2	IPR006117
Domain	25A_SYNTH_3	OAS3 OASL	9.07e-04	4	232	2	PS50152
Domain	2-5-oligoAdlate_synth_1_dom2/C	OAS3 OASL	9.07e-04	4	232	2	IPR018952
Domain	2-5A_synthase	OAS3 OASL	9.07e-04	4	232	2	IPR026774
Domain	-	OAS3 OASL	9.07e-04	4	232	2	1.10.1410.20
Domain	25A_SYNTH_1	OAS3 OASL	9.07e-04	4	232	2	PS00832
Domain	25A_SYNTH_2	OAS3 OASL	9.07e-04	4	232	2	PS00833
Domain	VPS13_C	VPS13D VPS13B	9.07e-04	4	232	2	PF16909
Domain	VPS13_C	VPS13D VPS13B	9.07e-04	4	232	2	IPR031645
Domain	SHR-BD	VPS13D VPS13B	9.07e-04	4	232	2	PF06650
Domain	BACK	KBTBD3 BTBD6 KLHL30 KBTBD6 KLHL12	9.57e-04	61	232	5	IPR011705
Domain	BACK	KBTBD3 BTBD6 KLHL30 KBTBD6 KLHL12	9.57e-04	61	232	5	PF07707
Domain	Kinase-like_dom	ABL1 ABL2 TRPM7 WDR81 CHEK1 MELK PIK3C2A PIK3CD STRADA PI4KA BUB1B MAP3K8 CIT IRAK3 PRKDC ATM	1.27e-03	542	232	16	IPR011009
Domain	2-5-oligoadenylate_synth_N	OAS3 OASL	1.50e-03	5	232	2	IPR006116
Domain	FATC	PRKDC ATM	1.50e-03	5	232	2	PF02260
Domain	Fd_Rdtase_FAD-bd	DUOX1 DUOX2 OXNAD1	1.58e-03	19	232	3	IPR017927
Domain	FAD_FR	DUOX1 DUOX2 OXNAD1	1.58e-03	19	232	3	PS51384
Domain	Riboflavin_synthase-like_b-brl	DUOX1 DUOX2 OXNAD1	1.58e-03	19	232	3	IPR017938
Domain	FAT	PRKDC ATM	2.23e-03	6	232	2	PS51189
Domain	FATC	PRKDC ATM	2.23e-03	6	232	2	PS51190
Domain	FAT	PRKDC ATM	2.23e-03	6	232	2	PF02259
Domain	PIK-rel_kinase_FAT	PRKDC ATM	2.23e-03	6	232	2	IPR003151
Domain	FATC_dom	PRKDC ATM	2.23e-03	6	232	2	IPR003152
Domain	PIK_FAT	PRKDC ATM	2.23e-03	6	232	2	IPR014009
Domain	FATC	PRKDC ATM	2.23e-03	6	232	2	SM01343
Pubmed	The human and murine protocadherin-beta one-exon gene families show high evolutionary conservation, despite the difference in gene number.	PCDHB15 PCDHB14 PCDHB12 PCDHB11 PCDHB10 PCDHB9 PCDHB7 PCDHB3 PCDHB16	8.62e-15	20	256	9	11322959
Pubmed	Protocadherins.	PCDHB14 PCDHB11 PCDHB10 PCDHB9 PCDHB3 PCDHB16	2.47e-10	13	256	6	12231349
Pubmed	Clustered gamma-protocadherins regulate cortical interneuron programmed cell death.	PCDHB15 PCDHB14 PCDHB12 PCDHB11 PCDHB10 PCDHB9 PCDHB7 PCDHB3 PCDHB16	3.64e-10	57	256	9	32633719
Pubmed	CTCF Governs the Identity and Migration of MGE-Derived Cortical Interneurons.	PCDHB15 PCDHB14 PCDHB12 PCDHB11 PCDHB10 PCDHB9 PCDHB7 PCDHB3 PCDHB16	4.28e-10	58	256	9	30377227
Pubmed	Comparative DNA sequence analysis of mouse and human protocadherin gene clusters.	PCDHB15 PCDHB14 PCDHB12 PCDHB11 PCDHB10 PCDHB9 PCDHB7 PCDHB3 PCDHB16	1.86e-09	68	256	9	11230163
Pubmed	Novel retinal and cone photoreceptor transcripts revealed by human macular expression profiling.	NPIPA1 NPIPA5 NPIPA3 NPIPA2	2.87e-09	4	256	4	18055785
Pubmed	Many human endogenous retrovirus K (HERV-K) proviruses are unique to humans.	ERVK-6 ERVK-7 ERVK-10 ERVK-24	2.87e-09	4	256	4	10469592
Pubmed	A striking organization of a large family of human neural cadherin-like cell adhesion genes.	PCDHB15 PCDHB14 PCDHB12 PCDHB11 PCDHB10 PCDHB9 PCDHB7 PCDHB3 PCDHB16	3.13e-09	72	256	9	10380929
Pubmed	Cadherin superfamily genes: functions, genomic organization, and neurologic diversity.	PCDHB15 PCDHB14 PCDHB12 PCDHB11 PCDHB10 PCDHB9 PCDHB7 PCDHB3 PCDHB16	4.01e-09	74	256	9	10817752
Pubmed	Single-neuron diversity generated by Protocadherin-β cluster in mouse central and peripheral nervous systems.	PCDHB15 PCDHB12 PCDHB11 PCDHB7 PCDHB3	5.08e-09	10	256	5	22969705
Pubmed	Phylogenetic analysis of the cadherin superfamily allows identification of six major subfamilies besides several solitary members.	PCDHB15 PCDHB14 PCDHB12 PCDHB11 PCDHB10 PCDHB9 PCDHB7 PCDHB3 PCDHB16	5.75e-09	77	256	9	10835267
Pubmed	Large exons encoding multiple ectodomains are a characteristic feature of protocadherin genes.	PCDHB15 PCDHB14 PCDHB12 PCDHB11 PCDHB10 PCDHB9 PCDHB7 PCDHB3 PCDHB16	8.11e-09	80	256	9	10716726
Pubmed	Quantitation of HERV-K env gene expression and splicing in human breast cancer.	ERVK-6 ERVK-7 ERVK-21 ERVK-19	1.43e-08	5	256	4	12629516
Pubmed	Genomewide screening for fusogenic human endogenous retrovirus envelopes identifies syncytin 2, a gene conserved on primate evolution.	ERVK-6 ERVK-21 ERVK-9 ERVK-19 ERVK-8	1.58e-08	12	256	5	14557543
Pubmed	A revised nomenclature for transcribed human endogenous retroviral loci.	ERVK-6 ERVK-7 ERVK-21 ERVK-9 ERVK-10 ERVK-19 ERVK-24 ERVK-8	4.98e-07	94	256	8	21542922
Pubmed	A dual-activity topoisomerase complex regulates mRNA translation and turnover.	PDE4A ABL1 PIEZO1 INTS1 PTCH1 KCNG1 PIK3CD PI4KA TIGD3 NLE1 DTX2 ALOX5 MED13 CRYBG2 CTC1 LAMA5 MED13L CIT SLC1A5 NISCH PPP1R15B SLC7A5 PRKDC SLC45A1 ALKBH6	7.79e-07	1105	256	25	35748872
Pubmed	Heterodimerization controls localization of Duox-DuoxA NADPH oxidases in airway cells.	DUOX1 DUOXA2 DUOX2	1.57e-06	4	256	3	19339556
Pubmed	The type of DUOX-dependent ROS production is dictated by defined sequences in DUOXA.	DUOX1 DUOXA2 DUOX2	1.57e-06	4	256	3	22814254
Pubmed	Human endogenous retrovirus K10: expression of Gag protein and detection of antibodies in patients with seminomas.	ERVK-6 ERVK-10 ERVK-19	1.57e-06	4	256	3	7983737
Pubmed	Mechanosensitive brain tumor cells construct blood-tumor barrier to mask chemosensitivity.	PIEZO1 PTCH1 PIEZO2	3.90e-06	5	256	3	36323321
Pubmed	Three Tctn proteins are functionally conserved in the regulation of neural tube patterning and Gli3 processing but not ciliogenesis and Hedgehog signaling in the mouse.	TCTN3 ISL1 PTCH1 ISL2	4.87e-06	16	256	4	28800946
Pubmed	Hereditary Ataxia Overview	TRPC3 CYP27A1 ELOVL4 ATXN10 RFC1 VPS13D ATM	5.55e-06	92	256	7	20301317
Pubmed	Postsynaptic and differential localization to neuronal subtypes of protocadherin beta16 in the mammalian central nervous system.	PCDHB15 PCDHB12 PCDHB11 PCDHB3	6.33e-06	17	256	4	18279309
Pubmed	Cell Surface Proteomic Map of HIV Infection Reveals Antagonism of Amino Acid Metabolism by Vpu and Nef.	TRPM7 PIEZO1 NRXN3 PTPRK EIF2B5 SLC39A6 SLC1A5 SLC7A5	6.48e-06	132	256	8	26439863
Pubmed	LMBR1L regulates lymphopoiesis through Wnt/β-catenin signaling.	CLSTN3 EMC1 FASTKD5 DCAF16 GALNT7 CEP78 PTPRK PI4KA ANAPC2 EIF2B5 UTP20 ATXN10 NAA15 SGSH FLVCR1 RDH14 SLC1A5 APH1A NISCH PRKDC HADHB	7.73e-06	942	256	21	31073040
Pubmed	APX-115, a first-in-class pan-NADPH oxidase (Nox) inhibitor, protects db/db mice from renal injury.	DUOX1 DUOX2 LEPR	7.76e-06	6	256	3	28165467
Pubmed	RAG-2 deficiency results in fewer phosphorylated histone H2AX foci, but increased retinal ganglion cell death and altered axonal growth.	ISL1 ISL2 PRKDC	7.76e-06	6	256	3	31811168
Pubmed	Human endogenous retrovirus HERV-K(HML-2) proviruses with Rec protein coding capacity and transcriptional activity.	ERVK-6 ERVK-9 ERVK-19	7.76e-06	6	256	3	15063128
Pubmed	The complexity of p53 modulation: emerging patterns from divergent signals.	CHEK1 PRKDC ATM	7.76e-06	6	256	3	9765199
Pubmed	Expression patterns of transcribed human endogenous retrovirus HERV-K(HML-2) loci in human tissues and the need for a HERV Transcriptome Project.	ERVK-21 ERVK-9 ERVK-10 ERVK-24	8.09e-06	18	256	4	18664271
Pubmed	The human homologs of checkpoint kinases Chk1 and Cds1 (Chk2) phosphorylate p53 at multiple DNA damage-inducible sites.	CHEK1 PRKDC ATM	1.35e-05	7	256	3	10673501
Pubmed	Identification of novel cadherins expressed in human melanoma cells.	PCDHB14 PCDHB11 PCDHB16	1.35e-05	7	256	3	9182820
Pubmed	Up-regulated expression of a novel gene in activated human peripheral blood mononuclear cells that is a truncated paralog of the human system L-amino acid transporter 1.	SLC7A5P2 SLC7A5 SLC7A5P1	1.35e-05	7	256	3	12009310
Pubmed	Mesenchymal cell TRPM7 expression is required for bone formation via the regulation of chondrogenesis.	TRPM7 MMP13 TNFRSF11B	1.35e-05	7	256	3	36210025
Pubmed	Comprehensive interactome profiling of the human Hsp70 network highlights functional differentiation of J domains.	EMC1 TRPM7 PIEZO1 FASTKD5 SCD5 DMXL1 PIK3C2A CASKIN2 PI4KA BUB1B SLC39A6 NLE1 ATXN10 LRRC41 NAA15 FLVCR1 SLC1A5 THEM4 GTF3C2 NISCH PPP1R15B SLC7A5 TTC17 ATM HADHB MMAB VPS13B	1.63e-05	1487	256	27	33957083
Pubmed	The Rfx4 transcription factor modulates Shh signaling by regional control of ciliogenesis.	ISL1 PTCH1 ISL2 RFX1	1.89e-05	22	256	4	19887680
Pubmed	Loss of Tctn3 causes neuronal apoptosis and neural tube defects in mice.	TCTN3 ISL1 PTCH1 ISL2	1.89e-05	22	256	4	29725084
Pubmed	RSG1 is required for cilia-dependent neural tube closure.	ISL1 PTCH1 ISL2	2.15e-05	8	256	3	38721990
Pubmed	Tectonic, a novel regulator of the Hedgehog pathway required for both activation and inhibition.	TCTN3 ISL1 PTCH1 ISL2	2.27e-05	23	256	4	16357211
Pubmed	Functional genetic analysis of mouse chromosome 11.	WDR81 NLE1 MED13 MPDU1	2.27e-05	23	256	4	12955145
Pubmed	β-dystroglycan is regulated by a balance between WWP1-mediated degradation and protection from WWP1 by dystrophin and utrophin.	ATXN10 GPRC5A SLC1A5 PRKDC	2.71e-05	24	256	4	29635000
Pubmed	Gli2, but not Gli1, is required for initial Shh signaling and ectopic activation of the Shh pathway.	ISL1 PTCH1 ISL2	3.20e-05	9	256	3	12361967
Pubmed	Substrate specificities and identification of putative substrates of ATM kinase family members.	ABL1 CHEK1 PRKDC ATM	3.21e-05	25	256	4	10608806
Pubmed	Differential requirement for Gli2 and Gli3 in ventral neural cell fate specification.	ISL1 PTCH1 ISL2	4.55e-05	10	256	3	12812795
Pubmed	Survey of human genes of retroviral origin: identification and transcriptome of the genes with coding capacity for complete envelope proteins.	ERVK-6 ERVK-21 ERVK-19	4.55e-05	10	256	3	12970426
Pubmed	Digenic DUOX1 and DUOX2 Mutations in Cases With Congenital Hypothyroidism.	DUOX1 DUOX2	5.40e-05	2	256	2	28633507
Pubmed	Integrin-mediated dendrite branch maintenance requires Abelson (Abl) family kinases.	ABL1 ABL2	5.40e-05	2	256	2	15987940
Pubmed	Recruitment of ATM protein to double strand DNA irradiated with ionizing radiation.	PRKDC ATM	5.40e-05	2	256	2	10464290
Pubmed	Regulation of the DNA Damage Response by DNA-PKcs Inhibitory Phosphorylation of ATM.	PRKDC ATM	5.40e-05	2	256	2	27939942
Pubmed	The Abl and Arg kinases mediate distinct modes of phagocytosis and are required for maximal Leishmania infection.	ABL1 ABL2	5.40e-05	2	256	2	22665498
Pubmed	Differential expression of PIEZO1 and PIEZO2 mechanosensitive channels in ocular tissues implicates diverse functional roles.	PIEZO1 PIEZO2	5.40e-05	2	256	2	37820892
Pubmed	Reactive oxygen species regulate the levels of dual oxidase (Duox1-2) in human neuroblastoma cells.	DUOX1 DUOX2	5.40e-05	2	256	2	22523549
Pubmed	The DNA damage response kinases DNA-dependent protein kinase (DNA-PK) and ataxia telangiectasia mutated (ATM) Are stimulated by bulky adduct-containing DNA.	PRKDC ATM	5.40e-05	2	256	2	21487018
Pubmed	Expression of dual oxidases and secreted cytokines in chronic rhinosinusitis.	DUOX1 DUOX2	5.40e-05	2	256	2	23281318
Pubmed	The expression of the non-receptor tyrosine kinases Arg and c-abl is differently modulated in B lymphoid cells at different stages of differentiation.	ABL1 ABL2	5.40e-05	2	256	2	12220663
Pubmed	When an Intramolecular Disulfide Bridge Governs the Interaction of DUOX2 with Its Partner DUOXA2.	DUOXA2 DUOX2	5.40e-05	2	256	2	25761904
Pubmed	Atm-dependent interactions of a mammalian chk1 homolog with meiotic chromosomes.	CHEK1 ATM	5.40e-05	2	256	2	9382850
Pubmed	Heterozygous Mutations of the DUOXA2 and DUOX2 Genes in Dizygotic Twins with Congenital Hypothyroidism.	DUOXA2 DUOX2	5.40e-05	2	256	2	27349010
Pubmed	Abl tyrosine kinase promotes dorsal ruffles but restrains lamellipodia extension during cell spreading on fibronectin.	ABL1 ABL2	5.40e-05	2	256	2	17686996
Pubmed	BAFF regulates activation of self-reactive T cells through B-cell dependent mechanisms and mediates protection in NOD mice.	TNFSF13B PRKDC	5.40e-05	2	256	2	24435807
Pubmed	The kinase activity of c-Abl but not v-Abl is potentiated by direct interaction with RFXI, a protein that binds the enhancers of several viruses and cell-cycle regulated genes.	ABL1 RFX1	5.40e-05	2	256	2	9583676
Pubmed	Conserved cysteine residues provide a protein-protein interaction surface in dual oxidase (DUOX) proteins.	DUOX1 DUOX2	5.40e-05	2	256	2	23362256
Pubmed	DUOX2/DUOXA2 Mutations Frequently Cause Congenital Hypothyroidism that Evades Detection on Newborn Screening in the United Kingdom.	DUOXA2 DUOX2	5.40e-05	2	256	2	31044655
Pubmed	Targeted Suppression and Knockout of ASCT2 or LAT1 in Epithelial and Mesenchymal Human Liver Cancer Cells Fail to Inhibit Growth.	SLC1A5 SLC7A5	5.40e-05	2	256	2	30029480
Pubmed	Roles of DNA-dependent protein kinase and ATM in cell-cycle-dependent radiation sensitivity in human cells.	PRKDC ATM	5.40e-05	2	256	2	12065055
Pubmed	The role of PIEZO ion channels in the musculoskeletal system.	PIEZO1 PIEZO2	5.40e-05	2	256	2	36717101
Pubmed	Ataxia telangiectasia mutated (ATM) is essential for DNA-PKcs phosphorylations at the Thr-2609 cluster upon DNA double strand break.	PRKDC ATM	5.40e-05	2	256	2	17189255
Pubmed	A point mutation in translation initiation factor eIF2B leads to function--and time-specific changes in brain gene expression.	EIF2B5 EIF2B1	5.40e-05	2	256	2	22073122
Pubmed	Characterization of ThOX proteins as components of the thyroid H(2)O(2)-generating system.	DUOX1 DUOX2	5.40e-05	2	256	2	11822874
Pubmed	AIF-mediated caspase-independent necroptosis requires ATM and DNA-PK-induced histone H2AX Ser139 phosphorylation.	PRKDC ATM	5.40e-05	2	256	2	22972376
Pubmed	Dual oxidase 1 and 2 expression in airway epithelium of smokers and patients with mild/moderate chronic obstructive pulmonary disease.	DUOX1 DUOX2	5.40e-05	2	256	2	18177232
Pubmed	Abl family tyrosine kinases regulate sialylated ganglioside receptors for polyomavirus.	ABL1 ABL2	5.40e-05	2	256	2	20181697
Pubmed	A Plug-and-Latch Mechanism for Gating the Mechanosensitive Piezo Channel.	PIEZO1 PIEZO2	5.40e-05	2	256	2	32142647
Pubmed	Transcriptional activity of multiple copies of a subtelomerically located olfactory receptor gene that is polymorphic in number and location.	OR4F4 OR4F17	5.40e-05	2	256	2	11689484
Pubmed	Comparative sequencing of a multicopy subtelomeric region containing olfactory receptor genes reveals multiple interactions between non-homologous chromosomes.	OR4F4 OR4F17	5.40e-05	2	256	2	11689483
Pubmed	Alternative splicing of myeloid IgA Fc receptor (Fc alpha R, CD89) transcripts in inflammatory responses.	PTCH1 FCAR	5.40e-05	2	256	2	12560105
Pubmed	Dual oxidases represent novel hydrogen peroxide sources supporting mucosal surface host defense.	DUOX1 DUOX2	5.40e-05	2	256	2	12824283
Pubmed	DNA-PKcs and ATM modulate mitochondrial ADP-ATP exchange as an oxidative stress checkpoint mechanism.	PRKDC ATM	5.40e-05	2	256	2	36727301
Pubmed	c-Abl and Arg tyrosine kinases regulate lysosomal degradation of the oncoprotein Galectin-3.	ABL1 ABL2	5.40e-05	2	256	2	20150913
Pubmed	DUOX2 and DUOXA2 Variants Confer Susceptibility to Thyroid Dysgenesis and Gland-in-situ With Congenital Hypothyroidism.	DUOXA2 DUOX2	5.40e-05	2	256	2	32425884
Pubmed	Eukaryotic initiation factor 2B epsilon induces cap-dependent translation and skeletal muscle hypertrophy.	EIF2B5 EIF2B1	5.40e-05	2	256	2	21486778
Pubmed	Positive selection of a gene family during the emergence of humans and African apes.	NPIPA1 NPIPA8	5.40e-05	2	256	2	11586358
Pubmed	Roles of DUOX-mediated hydrogen peroxide in metabolism, host defense, and signaling.	DUOX1 DUOX2	5.40e-05	2	256	2	24161126
Pubmed	Compound Heterozygous Mutations in the DUOX2/DUOXA2 Genes Cause Congenital Hypothyroidism.	DUOXA2 DUOX2	5.40e-05	2	256	2	28541007
Pubmed	Global Regulation of Differential Gene Expression by c-Abl/Arg Oncogenic Kinases.	ABL1 ABL2	5.40e-05	2	256	2	28555614
Pubmed	BCR/ABL downregulates DNA-PK(CS)-dependent and upregulates backup non-homologous end joining in leukemic cells.	ABL1 PRKDC	5.40e-05	2	256	2	19697154
Pubmed	Loss of dendrite stabilization by the Abl-related gene (Arg) kinase regulates behavioral flexibility and sensitivity to cocaine.	ABL1 ABL2	5.40e-05	2	256	2	19805386
Pubmed	Expression of human endogenous retrovirus type K envelope glycoprotein in insect and mammalian cells.	ERVK-6 ERVK-19	5.40e-05	2	256	2	9060628
Pubmed	Activation of ATM/Chk1 by curcumin causes cell cycle arrest and apoptosis in human pancreatic cancer cells.	CHEK1 ATM	5.40e-05	2	256	2	19401701
Pubmed	Poor cerebral inflammatory response in eIF2B knock-in mice: implications for the aetiology of vanishing white matter disease.	EIF2B5 EIF2B1	5.40e-05	2	256	2	23056417
Pubmed	Targeting DNA-PKcs and ATM with miR-101 sensitizes tumors to radiation.	PRKDC ATM	5.40e-05	2	256	2	20617180
Pubmed	Mechanosensitive channels: in touch with Piezo.	PIEZO1 PIEZO2	5.40e-05	2	256	2	21056836
Pubmed	Differential regulation of dual NADPH oxidases/peroxidases, Duox1 and Duox2, by Th1 and Th2 cytokines in respiratory tract epithelium.	DUOX1 DUOX2	5.40e-05	2	256	2	16111680
Pubmed	The p110delta isoform of phosphatidylinositol 3-kinase controls susceptibility to Leishmania major by regulating expansion and tissue homing of regulatory T cells.	PIK3CD PRKDC	5.40e-05	2	256	2	19596993
Pubmed	Non-obese diabetic mice rapidly develop dramatic sympathetic neuritic dystrophy: a new experimental model of diabetic autonomic neuropathy.	LEPR PRKDC	5.40e-05	2	256	2	14578206
Pubmed	Astrocytes in the optic nerve head express putative mechanosensitive channels.	PIEZO1 PIEZO2	5.40e-05	2	256	2	26236150
Pubmed	Axonal and Glial PIEZO1 and PIEZO2 Immunoreactivity in Human Clitoral Krause's Corpuscles.	PIEZO1 PIEZO2	5.40e-05	2	256	2	38928429
Pubmed	A hydrophobic gate in the inner pore helix is the major determinant of inactivation in mechanosensitive Piezo channels.	PIEZO1 PIEZO2	5.40e-05	2	256	2	30628892
Pubmed	Nox/Duox family of nicotinamide adenine dinucleotide (phosphate) oxidases.	DUOX1 DUOX2	5.40e-05	2	256	2	11753072
Pubmed	Piezo1 ion channel pore properties are dictated by C-terminal region.	PIEZO1 PIEZO2	5.40e-05	2	256	2	26008989
Cytoband	5q31	MYOT PCDHB15 PCDHB14 PCDHB12 PCDHB11 PCDHB10 PCDHB9 PCDHB7 PCDHB3 PCDHB16	1.05e-09	115	255	10	5q31
Cytoband	16p12.2	NPIPB4 NPIPB3 NPIPB5 SLC7A5P2 SDR42E2	1.92e-06	37	255	5	16p12.2
Cytoband	Ensembl 112 genes in cytogenetic band chr16p12	NPIPB4 NPIPB3 NPIPB5 NPIPB6 SLC7A5P2 DNAH3 NPIPA8 SDR42E2	5.97e-06	172	255	8	chr16p12
Cytoband	Ensembl 112 genes in cytogenetic band chr5q31	MYOT PCDHB15 PCDHB14 PCDHB12 PCDHB11 PCDHB10 PCDHB9 PCDHB7 PCDHB3 PCDHB16	7.57e-06	298	255	10	chr5q31
Cytoband	16p13.11	NPIPA1 NPIPA5 NPIPA3 NPIPA2	7.58e-06	23	255	4	16p13.11
Cytoband	3q12.1	OR5H15 OR5H14 OR5H8	2.09e-04	21	255	3	3q12.1
Cytoband	Ensembl 112 genes in cytogenetic band chr3q11	OR5H1 OR5H15 OR5H14 OR5H8	2.36e-04	54	255	4	chr3q11
GeneFamily	Clustered protocadherins	PCDHB15 PCDHB14 PCDHB12 PCDHB11 PCDHB10 PCDHB9 PCDHB7 PCDHB3 PCDHB16	3.86e-09	64	156	9	20
GeneFamily	Solute carriers	SLC22A15 SLC36A2 SLC39A6 SLC26A3 SLC2A9 FLVCR1 SLC1A5 SLC17A1 SLC7A5 SLC45A1 SLC4A11 SLC44A3	1.67e-04	395	156	12	752
GeneFamily	Short chain dehydrogenase/reductase superfamily	DHRS1 RDH14 RDH5 SDR42E2 HSD17B6	5.06e-04	76	156	5	743
GeneFamily	Fatty acid desaturases	SCD5 DEGS2	2.00e-03	8	156	2	553
GeneFamily	Phosphatidylinositol 3-kinase subunits	PIK3C2A PIK3CD	2.00e-03	8	156	2	831
Coexpression	MIKKELSEN_ES_HCP_WITH_H3K27ME3	PCDHB15 PCDHB14 PCDHB12 PCDHB11 PCDHB7 PCDHB16	2.31e-06	42	242	6	MM1275
CoexpressionAtlas	PP_RBC_top-relative-expression-ranked_2500_k-means-cluster#3	PDE4A COLQ ALOX5 MYOT PCDHB15 PCDHB14 PCDHB12 PCDHB11 PCDHB10 PCDHB9 PCDHB3	1.06e-06	158	226	11	PP_RBC_2500_K3
ToppCell	facs-Trachea-18m-Mesenchymal-myofibroblast-tracheobronchial_smooth_muscle_cell-smooth_muscle_cell_of_trachea_l1\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	TCTN3 CLSTN3 KLHL30 GBGT1 MMP13 PCDHB14 PCDHB3 RDH5 LEPR	2.53e-07	157	248	9	1f21d78a467fe22c5ab75d0917b840c1ac93f32c
ToppCell	normal_Pleural_Fluid-Myeloid_cells-CD163+CD14+_DCs\|normal_Pleural_Fluid / Location, Cell class and cell subclass	PIEZO1 SLC22A15 CFAP54 STRADA BUB1B POFUT2 LEPR CDYL2	6.67e-06	176	248	8	7a74217b7fa1032b918f00a3972dff5fab74671a
ToppCell	tumor_Lymph_Node_/_Brain-Myeloid_cells-Activated_DCs\|tumor_Lymph_Node_/_Brain / Location, Cell class and cell subclass	NPIPB4 NPIPB5 STRADA GBGT1 TRABD2A TNFRSF11B EGR4 TNFSF13B	7.86e-06	180	248	8	aae85fb3c92a45614616a3ee3a1af5244cc299a7
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell-Descending_Thin_Limb_Cell_Type_2\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	TRPC3 CFAP54 ADAMTS16 TDO2 TNFRSF11B FUT9 HYDIN SLC4A11	8.53e-06	182	248	8	5e1b316599436740f1b30875f0ebd33c3edfb2b6
ToppCell	Adult-Epithelial-alveolar_epithelial_cell_type_1-D122\|Adult / Lineage, Cell type, age group and donor	UNC13D SCD5 WWC2 PTPRQ LAMA5 MYO1B GPRC5A SLC44A3	9.23e-06	184	248	8	561592edc3083fad41b91811151b442207c65dd9
ToppCell	renal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell-Descending_Thin_Limb_Cell_Type_2\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	TRPC3 CFAP54 ADAMTS16 TDO2 TNFRSF11B FUT9 HYDIN SLC4A11	9.99e-06	186	248	8	5c4ffe4e4d5536ae9f8794277fe032c693e7dd56
ToppCell	Fetal_29-31_weeks-Epithelial-alveolar_epithelial_cell_type_1\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	UNC13D SCD5 WWC2 PTPRQ LAMA5 MYO1B GPRC5A SLC44A3	1.08e-05	188	248	8	eea652bab161f19148a883e7e3fe2523b36b3cea
ToppCell	367C-Lymphocytic-NK_cells-NK_cell_B1\|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)	FASTKD5 SCD5 ANAPC2 UTP20 ARHGEF12 TMEM267 OASL VPS41	1.21e-05	191	248	8	39ef8e1d7cc3ebb11717e8a55501515e3b72b177
ToppCell	CD8+_Memory_T_cell-CV-7\|CD8+_Memory_T_cell / cell class, Virus stimulation and cluster	TRPM7 NPIPB5 WDR7 SLC1A5 PPP1R15B SLC7A5 TTC17 PRKDC	1.21e-05	191	248	8	9454f642c3621370fa23640b631301346b300950
ToppCell	Bronchial-NucSeq\|Bronchial / Cell types per location group and 10X technology with lineage, and cell group designations	KANSL1L PTPRK SLC26A3 MED13L ZHX2 FARS2 HERC4 VPS13B	1.46e-05	196	248	8	ab53c742866945545a92e2e61850d63c80d9a2a6
ToppCell	LPS_only-Epithelial_airway-Ciliated_cells-Ciliated\|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	CFAP54 USH2A TRMT9B DNAH3 IQCH ALKBH6 HYDIN	2.53e-05	154	248	7	9ca71d440c4f87781e6525b8141e7d8d470b6a8e
ToppCell	LPS_only-Epithelial_airway-Ciliated_cells\|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	CFAP54 USH2A TRMT9B DNAH3 IQCH ALKBH6 HYDIN	2.53e-05	154	248	7	58072ce422d09f2de602580325eaac6c4ec6c136
ToppCell	LPS-IL1RA+antiTNF-Epithelial_airway-Ciliated_cells\|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	CFAP54 DEGS2 DUOXA2 DNAH3 IQCH DUOX2 HYDIN	2.64e-05	155	248	7	5f1e2195a6b831e1b636f5cc3a282ca423721822
ToppCell	LPS-IL1RA+antiTNF-Epithelial_airway-Ciliated_cells-Ciliated\|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	CFAP54 DEGS2 DUOXA2 DNAH3 IQCH DUOX2 HYDIN	2.64e-05	155	248	7	0944429459f642a1bcc56edc1ec28aaecde3e2dc
ToppCell	facs-Lung-24m-Endothelial-capillary_endothelial-capillary_endothelial_cell-capillary_type_1_endothelial_cell\|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	PTPRQ USH2A SLC26A3 DUOX2 FUT9 RIMS2 HYDIN	3.50e-05	162	248	7	bf886e22ff2a20353499004b53f25fb9e6574896
ToppCell	cellseq-Immune-Lymphocytic_T/NK-Lymphocytic_T/NK-ILC\|cellseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	ELOVL4 PIK3CD NPIPB6 OR5H14 OXNAD1 SLC7A5 SENP7	3.50e-05	162	248	7	553f91eaba72bcffb733ede45418bbee39c653ab
ToppCell	390C-Epithelial_cells-Epithelial-I_(AT1)\|Epithelial_cells / Donor, Lineage, Cell class and subclass (all cells)	KBTBD3 PIEZO1 NPIPA1 UNC13D IFIH1 POFUT2 LAMA5	4.59e-05	169	248	7	665b958f4a720ca369a8a0abc7fbe8b6e13c8ce5
ToppCell	390C-Epithelial_cells-Epithelial-I_(AT1)-\|Epithelial_cells / Donor, Lineage, Cell class and subclass (all cells)	KBTBD3 PIEZO1 NPIPA1 UNC13D IFIH1 POFUT2 LAMA5	4.59e-05	169	248	7	6614c9851537e4c21b1e45ff0cc3bad07ef9d034
ToppCell	Children_(3_yrs)-Epithelial-alveolar_epithelial_cell_type_1/2_(AT1/AT2-like)-D032\|Children_(3_yrs) / Lineage, Cell type, age group and donor	WWC2 PTPRK LAMA5 MYO1B GPRC5A CIT HSD17B6	4.76e-05	170	248	7	a2c738e441ced90eeeb1fcc6ca3269b918aaa298
ToppCell	facs-Marrow-Granulocytes-24m-Hematologic-hematopoietic_stem_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	HEXB TMEM141 GBGT1 EVC2 LAMA5 MYO1B TDO2	4.76e-05	170	248	7	8d3c51364a332020810836e2055c60893c10d7f3
ToppCell	3'-Parenchyma_lung-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.2.1\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	DUOX1 DNAH3 ZDHHC11B IQCH ARHGAP39 SDR42E2 HYDIN	4.94e-05	171	248	7	1854a777d9eb9d3fc3ed3632332a6f89ce8131da
ToppCell	CD8+_Memory_T_cell-FLU-3\|CD8+_Memory_T_cell / cell class, Virus stimulation and cluster	CHEK1 CFAP54 PTPRK SLC39A6 IQCH DHX37 TUBD1	5.13e-05	172	248	7	45ac433dbb3796f69e886c04457b2971403050ee
ToppCell	facs-Lung-Endomucin_-18m-Myeloid-non-classical_monocyte\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PIK3CD DEGS2 ALOX5 INTS6L SLC2A9 GPR35 GDA	5.32e-05	173	248	7	c31076c725f4cd912c56903592a2d9356ae59f54
ToppCell	facs-Lung-Endomucin_-18m-Myeloid-Nonclassical_Monocyte\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PIK3CD DEGS2 ALOX5 INTS6L SLC2A9 GPR35 GDA	5.32e-05	173	248	7	a4ed191cfdf6588b7f3672995bf0a4fe9e4b8df6
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell-Descending_Thin_Limb_Cell_Type_2\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	TRPC3 CFAP54 TNFRSF11B VPS41 FUT9 HYDIN SLC4A11	5.72e-05	175	248	7	284fdc7a9d303636a637041846850d19d114861a
ToppCell	PBMC_fresh-frozen-Severe-critical_progression_d12-22_with-steroid-Lymphocytic-Lymphocytic_T-CD8-positive,_alpha-beta_T_cell-T_CD8_c03-GZMK\|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)	NPIPB3 MAP3K8 ISL2 SLC1A5 EGR4 OASL SLC7A5	6.14e-05	177	248	7	84930899eb2978598bc8a351cbcd9e714e46799d
ToppCell	343B-Myeloid-Macrophage-FABP4+_Macrophage\|Macrophage / Donor, Lineage, Cell class and subclass (all cells)	SLC22A15 ACOD1 PIK3CD PAPOLG ZNF286A SENP7	6.26e-05	122	248	6	a2f343962069253a08faa80fd70723b8488a99ec
ToppCell	COVID-19-Epithelial_cells-AT1\|COVID-19 / group, cell type (main and fine annotations)	SCD5 WWC2 DUOX1 LAMA5 MYO1B GPRC5A SLC44A3	6.59e-05	179	248	7	a0b33bd69ffdfd5d38d80207fb40058a490aa19e
ToppCell	droplet-Thymus-nan-24m-Lymphocytic-DN3_thymocyte\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TMEM141 F8 LRRC41 FAM228B CDYL2 MMAB ZNF286A	7.07e-05	181	248	7	e2d03115a87f45a7ddd3ade6b9ac3843639bd41a
ToppCell	LPS-antiTNF-Epithelial_alveolar-AT_1-Differentiating_AT1\|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	UNC13D SCD5 WWC2 NRXN3 PTPRQ MYO1B GPRC5A	7.07e-05	181	248	7	b45b11428d13950369347e051d4d517efb2bd4fd
ToppCell	droplet-Thymus-nan-24m-Lymphocytic-Double_negative_thymocyte,_DN3_(Cd8-,_Cd4-),_some_express_pre_TCR_alpha\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TMEM141 F8 LRRC41 FAM228B CDYL2 MMAB ZNF286A	7.07e-05	181	248	7	d8d11ef83c4b8b6a6f5c8728e03059e45a8ad264
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell-Descending_Thin_Limb_Cell_Type_2\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	TRPC3 CFAP54 TDO2 TNFRSF11B FUT9 HYDIN SLC4A11	7.07e-05	181	248	7	6956ecd6264f7469a25e555673bce4eb97d28f7a
ToppCell	PND01-Immune-Immune_Myeloid-Monocytic-Macrophage-AM-AM_prolif\|PND01 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	HEXB TRAF3 MANBA CHEK1 MELK EIF2B5 SGSH	7.32e-05	182	248	7	57f8b8d7b132f3ad6f2b1e79c3812fe938657d2c
ToppCell	COVID-19-lung-AT1\|COVID-19 / Disease (COVID-19 only), tissue and cell type	UNC13D SCD5 WWC2 DUOX1 LAMA5 MYO1B GPRC5A	7.57e-05	183	248	7	7b1a385ed54f93bfe85bf0c162e42d05d516b45c
ToppCell	343B-Epithelial_cells-Epithelial-I_(AT1)-\|Epithelial_cells / Donor, Lineage, Cell class and subclass (all cells)	PIEZO1 UNC13D SCD5 WWC2 KCNA4 LAMA5 GPRC5A	7.84e-05	184	248	7	c7073d1b2c4fdb154d87678b92a0629c02116972
ToppCell	343B-Epithelial_cells-Epithelial-I_(AT1)\|Epithelial_cells / Donor, Lineage, Cell class and subclass (all cells)	PIEZO1 UNC13D SCD5 WWC2 KCNA4 LAMA5 GPRC5A	7.84e-05	184	248	7	1ed558a88215b248431c524ea16f13d9022ae98c
ToppCell	390C-Lymphocytic-CD4_T-cell-Treg_cell_1\|390C / Donor, Lineage, Cell class and subclass (all cells)	FASTKD5 FBXL18 INTS6L KBTBD6 ZHX2 VPS13D ZNF286A	8.39e-05	186	248	7	064b6047215597465bb51a8a1547ef5a226552f9
ToppCell	Epithelial-alveolar_epithelial_cell_type_1\|World / Lineage, Cell type, age group and donor	UNC13D SCD5 WWC2 PTPRQ LAMA5 MYO1B GPRC5A	8.39e-05	186	248	7	09d95daa3387a4814cffaa4b798cc2810c3759d0
ToppCell	Fetal_29-31_weeks-Epithelial-alveolar_epithelial_cell_type_1-D150\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	UNC13D SCD5 WWC2 PTPRQ LAMA5 GPRC5A SLC44A3	8.67e-05	187	248	7	4ae7465174e0295d2c3b614b321a3b2f514dd22a
ToppCell	Adult-Epithelial-alveolar_epithelial_cell_type_1\|Adult / Lineage, Cell type, age group and donor	UNC13D SCD5 WWC2 PTPRQ LAMA5 MYO1B GPRC5A	8.67e-05	187	248	7	77f78aec946bc6bd85c29aee9ca978ce49f853a3
ToppCell	390C-Lymphocytic-CD4_T-cell-Treg_cell_1\|CD4_T-cell / Donor, Lineage, Cell class and subclass (all cells)	FASTKD5 FBXL18 KBTBD6 ARHGEF12 ZHX2 VPS13D ZNF286A	8.97e-05	188	248	7	2c4e791df69a9df29922f9117e5cac7787c129ce
ToppCell	390C-Lymphocytic-CD4_T-cell-Treg_cell_1\|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)	FASTKD5 FBXL18 KBTBD6 ARHGEF12 ZHX2 VPS13D ZNF286A	8.97e-05	188	248	7	b1ec7c45aedcc3d22cac898c6a3679e7f8b44c77
ToppCell	368C-Lymphocytic-CD8+_Cytotoxic_T-cell-CD8+_Cytotoxic_T_cell_0.5\|368C / Donor, Lineage, Cell class and subclass (all cells)	KANSL1L PATL2 CEP78 TRABD2A SGSH GTF3C2 KLHL12	9.27e-05	189	248	7	610d7cc1fc923dbd67d3b71f94d529a658982f87
ToppCell	droplet-Lung-21m-Endothelial-lymphatic_endothelial-lymphatic_endothelial_cell-lymphatic_endothelial_cell\|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	ABL1 TRPC3 NRXN3 DUOXA2 PCDHB15 DUOX2 MYO1B	9.58e-05	190	248	7	f50b9814a1beac67dc042a8c27dfd085ceeda3a6
ToppCell	droplet-Lung-21m-Endothelial-lymphatic_endothelial-lymphatic_endothelial_cell\|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	ABL1 TRPC3 NRXN3 DUOXA2 PCDHB15 DUOX2 MYO1B	9.58e-05	190	248	7	a22a510b4a257eb0eaf09c7ae7978d3d2f07a58c
ToppCell	droplet-Lung-21m-Endothelial-lymphatic_endothelial\|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	ABL1 TRPC3 NRXN3 DUOXA2 PCDHB15 DUOX2 MYO1B	9.58e-05	190	248	7	57c136bf6d7feafb4a220877bed0cc8fdf314db2
ToppCell	Epithelial-alveolar_epithelial_cell_type_1/2_(AT1/AT2-like)\|World / Lineage, Cell type, age group and donor	WWC2 PTPRK LAMA5 MYO1B GPRC5A HSD17B6 SLC44A3	9.90e-05	191	248	7	d3733c8c4bda70c4390e5601fdda6188a64be944
ToppCell	Parenchymal-NucSeq-Stromal-Schwann-Schwann_nonmyelinating\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	CYP27A1 GALNT8 MYOT IGSF11 NPIPA7 SLC1A5	1.01e-04	133	248	6	b4e68a9a223e5188f1a00c7dc9bb2d675cde1d40
ToppCell	Parenchymal-NucSeq-Stromal-Schwann\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	CYP27A1 GALNT8 MYOT IGSF11 NPIPA7 SLC1A5	1.01e-04	133	248	6	8819fd897b97812355e1709fcc42754522d5fb27
ToppCell	facs-Heart-RV-18m-Mesenchymal-atrial_myocyte\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PTCH1 ALDH3B2 CIT GDA SLC45A1 HYDIN	1.05e-04	134	248	6	d101e16cb87ff72c81324406fe7e3d70ed8f45df
ToppCell	facs-Heart-RV-18m-Mesenchymal-atrial_cardiomyocyte\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PTCH1 ALDH3B2 CIT GDA SLC45A1 HYDIN	1.05e-04	134	248	6	0c63c8b3c748d29c59fcb27d03276ba4f6a0d6b2
ToppCell	nucseq\|World / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	MANBA NPIPB4 NPIPB3 NPIPB5 MED13L ZHX2 VPS13B	1.06e-04	193	248	7	779276e775cb2492e8dd36436295a536084a6415
ToppCell	moderate-Myeloid-Monocyte-derived_Macrophage\|Myeloid / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls	DCHS2 ACOD1 IFIH1 MMP13 OAS3 TNFRSF11B OASL	1.06e-04	193	248	7	22455801194bd8c73c5c397f5eac4f723429c383
ToppCell	390C-Epithelial_cells-Epithelial-I_(AT1)\|390C / Donor, Lineage, Cell class and subclass (all cells)	KBTBD3 PIEZO1 NPIPA1 IFIH1 POFUT2 LAMA5 ARHGAP5	1.09e-04	194	248	7	88db9f9e80c20ff3474f1f6459dcbdc25aec0b6d
ToppCell	390C-Epithelial_cells-Epithelial-I_(AT1)-\|390C / Donor, Lineage, Cell class and subclass (all cells)	KBTBD3 PIEZO1 NPIPA1 IFIH1 POFUT2 LAMA5 ARHGAP5	1.09e-04	194	248	7	a71728202493d4858342ea2756ea281cd0d99a3a
ToppCell	Children_(3_yrs)-Immune-alveolar_macrophage_(MARCO_positive)-D139\|Children_(3_yrs) / Lineage, Cell type, age group and donor	HEXB MANBA CYP27A1 SLC22A15 ALOX5 MAP3K8 IRAK3	1.13e-04	195	248	7	9d649ac7d2af313481069c95349efc0c68449e2b
ToppCell	Immune-alveolar_macrophage_(MARCO_positive)\|World / Lineage, Cell type, age group and donor	HEXB MANBA CYP27A1 SLC22A15 ALOX5 SLC2A9 IRAK3	1.13e-04	195	248	7	f92114ef995e690a3bedc62c89c5fd6773d0d9f7
ToppCell	Bronchial-NucSeq-Epithelial-Epi_alveolar-AT1\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	UNC13D SCD5 WWC2 PTPRQ LAMA5 MYO1B GPRC5A	1.13e-04	195	248	7	a71ba5e4043e2d35a45a2c60a96b087e31832345
ToppCell	Fetal_brain-organoid_Tanaka_cellReport-GW26-Mesenchymal-Unfolded_protein_responsible_cell\|GW26 / Sample Type, Dataset, Time_group, and Cell type.	PATL2 GALNT8 OSBP2 PCDHB14 GXYLT1 SLC1A5 CDYL2	1.13e-04	195	248	7	9873de83b67e9645112897d3391c2d9afaa9970e
ToppCell	Adult-Immune-alveolar_macrophage_(MARCO_positive)\|Adult / Lineage, Cell type, age group and donor	HEXB MANBA CYP27A1 ALOX5 SLC2A9 MAP3K8 IRAK3	1.13e-04	195	248	7	55e25f702af19146a161861cfd15f40bbda1dc35
ToppCell	facs-Pancreas-Exocrine-18m-Epithelial-nan\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	WDR7 PCDHB11 PCDHB7 GCNT7 MMAB TUBD1	1.19e-04	137	248	6	e9b88ad86b75454a8292a94879c5b665adc42744
ToppCell	5'-Parenchyma_lung-Epithelial-Alveolar_epithelium-type_I_pneumocyte-AT1-AT1_L.0.5.0.0\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	UNC13D SCD5 DUOX1 LAMA5 MYO1B GPRC5A HSD17B6	1.20e-04	197	248	7	734b8db5bb4917c9ce92ed342fe6c22b64b0d3c5
ToppCell	5'-Parenchyma_lung-Epithelial-Alveolar_epithelium-type_I_pneumocyte-AT1\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	UNC13D SCD5 DUOX1 LAMA5 MYO1B GPRC5A HSD17B6	1.20e-04	197	248	7	e344455e62b3fe94bb242dc0db58d19a1d3878c7
ToppCell	5'-Parenchyma_lung-Epithelial-Alveolar_epithelium-type_I_pneumocyte\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	UNC13D SCD5 DUOX1 LAMA5 MYO1B GPRC5A HSD17B6	1.20e-04	197	248	7	c9c968e223e7814cd8d22975d849a31b7e0af7aa
ToppCell	Parenchymal-NucSeq-Epithelial-Epi_alveolar-AT1\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	UNC13D SCD5 WWC2 PTPRQ LAMA5 MYO1B GPRC5A	1.20e-04	197	248	7	8d5097898dd01cedb04cb694cb480c931e08462c
ToppCell	primary_visual_cortex-Neuronal-glutamatergic_neuron-L2/3_IT-L2/3_IT_VISp_Rrad\|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	PTPRK ALDH3B2 EVC2 CAPN3 GPRC5A EGR4	1.24e-04	138	248	6	b3a040c5d0e1cc94d9b19155bca8700edba2d243
ToppCell	mLN-(1)_T_cell-(13)_Th17\|mLN / shred on region, Cell_type, and subtype	PDE4A PCDHB15 ARHGEF12 SLC1A5 TNFSF13B PPP1R15B SLC7A5	1.24e-04	198	248	7	c575e9aeee4e034e8c4d171fe754403652343731
ToppCell	mLN-T_cell-Th17\|mLN / Region, Cell class and subclass	PDE4A PCDHB15 ARHGEF12 SLC1A5 TNFSF13B PPP1R15B SLC7A5	1.24e-04	198	248	7	04905f62941b193864704a10ad692faf777fa51d
ToppCell	(7)_Epithelial_cells-(7)_Epithelial-I_(AT1)\|(7)_Epithelial_cells / Lung cell shreds - cell class (v4) and cell subclass (v4)	PIEZO1 UNC13D SCD5 WWC2 LAMA5 MYO1B GPRC5A	1.28e-04	199	248	7	5a002d49a8b84c158f7b4d7a3e78e6a937757bb7
ToppCell	LPS_anti-TNF-Epithelial_airway-airway_epithelial-Ciliated\|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type	CFAP54 FNDC11 ERICH6 DUOXA2 DNAH3 IQCH HYDIN	1.28e-04	199	248	7	15f7814b7074170eee7ccacaa670b1d128fc68bb
ToppCell	LPS_IL1RA_TNF-Epithelial_airway\|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type	ELOVL4 CFAP54 DUOXA2 DNAH3 IQCH DUOX2 HYDIN	1.32e-04	200	248	7	72c1d9eeaed4b3ee6b6c602e8aa29efc2e8744eb
ToppCell	LPS_IL1RA_TNF-Epithelial_airway-airway_epithelial\|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type	ELOVL4 CFAP54 DUOXA2 DNAH3 IQCH DUOX2 HYDIN	1.32e-04	200	248	7	da12821e8a0657869ca0f75d351cce2d7605a505
ToppCell	distal-Epithelial-Alveolar_Epithelial_Type_1-3\|distal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	SCD5 WWC2 PTPRQ MYO1B GPRC5A HSD17B6 SLC44A3	1.32e-04	200	248	7	ccd0edd483728279fe15d64be3a39e8636bf2eeb
Disease	Transient hypothyroxinaemia of prematurity	DUOXA2 DUOX2	5.69e-05	2	223	2	C3827793
Disease	monocyte percentage of leukocytes	MANBA ARID4B PIEZO1 SCD5 IFIH1 FBXL18 PI4KA TBC1D14 CRYBG2 GPR35 CAPN3 MED13L LEPR TNFSF13B PRKDC MMAB	1.53e-04	731	223	16	EFO_0007989
Disease	Colonic Polyps	TRPM7 ALOX5	1.70e-04	3	223	2	C0009376
Disease	blood pressure, response to thiazide, response to beta blocker	OR5H1 OR5H14	1.70e-04	3	223	2	EFO_0004325, EFO_0007766, EFO_0007981
Disease	phenylketonuria (implicated_via_orthology)	DUOX1 DUOX2	3.38e-04	4	223	2	DOID:9281 (implicated_via_orthology)
Disease	X-18888 measurement	THEM4 SLC17A1	3.38e-04	4	223	2	EFO_0800792
Disease	monocyte count	TRAF3 ARID4B OR6N2 TRPM7 PIEZO1 SCD5 PIK3CD PI4KA TBC1D14 CRYBG2 GPR35 CAPN3 ARHGEF12 MED13L LEPR THEM4 TNFSF13B HSD17B6 CDYL2 PRKDC ATM TUBD1	4.59e-04	1320	223	22	EFO_0005091
Disease	Medulloblastoma	PTCH1 STRADA BRD3 ATM	5.57e-04	50	223	4	C0025149
Disease	leukoencephalopathy with vanishing white matter (implicated_via_orthology)	EIF2B5 EIF2B1	5.60e-04	5	223	2	DOID:0060868 (implicated_via_orthology)
Disease	X-13431--nonanoylcarnitine measurement	KANSL1L THEM4	5.60e-04	5	223	2	EFO_0021349
Disease	Immunologic Deficiency Syndromes	LEPR EPG5 ATM	6.75e-04	23	223	3	C0021051
Disease	JT interval, response to sulfonylurea	NRXN3 IGSF11 FARS2	6.75e-04	23	223	3	EFO_0007885, EFO_0007922
Disease	lung squamous cell carcinoma (is_implicated_in)	PTCH1 SLC7A5 ATM	7.67e-04	24	223	3	DOID:3907 (is_implicated_in)
Disease	Vanishing white matter disease	EIF2B5 EIF2B1	8.36e-04	6	223	2	cv:C1858991
Disease	Thyroid Dyshormonogenesis 1	DUOXA2 DUOX2	8.36e-04	6	223	2	C1848805
Disease	OVARIOLEUKODYSTROPHY	EIF2B5 EIF2B1	8.36e-04	6	223	2	C1847967
Disease	X-23641 measurement	KANSL1L THEM4	1.16e-03	7	223	2	EFO_0800854
Disease	Disorder of eye	TCTN3 CYP27A1 ELOVL4 USH2A FLVCR1 RDH5 MFSD8	1.20e-03	212	223	7	C0015397
Disease	Congenital Hydrocephalus	WDR81 HYDIN	1.55e-03	8	223	2	C0020256
Disease	lymphocyte count	TCTN3 TRAF3 PDE4A ABL1 MANBA PIEZO1 SCD5 IFIH1 FBXL18 ANAPC1 PIK3CD TBC1D14 FLVCR1 BRD3 FCRLA MED13L LEPR TNFRSF11B TMEM267 TNFSF13B ATM TUBD1	1.75e-03	1464	223	22	EFO_0004587
Disease	microcephaly (implicated_via_orthology)	WDR81 DHX37 CIT	1.80e-03	32	223	3	DOID:10907 (implicated_via_orthology)
Disease	primary bacterial infectious disease (implicated_via_orthology)	DUOX1 DUOX2	1.98e-03	9	223	2	DOID:0050338 (implicated_via_orthology)
Disease	esophagus squamous cell carcinoma (is_marker_for)	PTCH1 SLC1A5 SLC7A5 ATM	2.42e-03	74	223	4	DOID:3748 (is_marker_for)
Disease	basophil count, eosinophil count	SCD5 ANAPC1 BRD3 TNFRSF11B MEIOSIN PRKDC ATM	2.48e-03	241	223	7	EFO_0004842, EFO_0005090
Disease	intellectual disability (implicated_via_orthology)	KANSL1L NAA16 NAA15 CAPN3	2.54e-03	75	223	4	DOID:1059 (implicated_via_orthology)
Disease	reticulocyte count	PIEZO1 CYP27A1 SCD5 KCNA4 FBXL18 MMP13 ALOX5 FLVCR1 MYO1B BRD3 RFC1 ZHX2 NPIPB2 TMEM267 NISCH SLC45A1 MMAB	2.61e-03	1045	223	17	EFO_0007986
Disease	hip bone mineral density	PTCH1 NRXN3 GALNT8 IGSF11 TNFRSF11B	2.75e-03	126	223	5	EFO_0007702
Disease	urate measurement, bone density	ADAMTS16 ALG8 USH2A SLC2A9 WDR7 RDH14 LAMA5 TDO2 MANSC1 TNFSF13B PRKDC SLC4A11	2.80e-03	619	223	12	EFO_0003923, EFO_0004531
Disease	urgency urinary incontinence	ADAMTS16 CIT	3.57e-03	12	223	2	EFO_0006865
Disease	lifestyle measurement, anxiety disorder measurement	CFAP54 KCNG1 GBGT1 USH2A PIEZO2	3.93e-03	137	223	5	EFO_0007795, EFO_0010724
Disease	Diverticular Bleeding	COLQ ISL2	4.20e-03	13	223	2	C4505353
Disease	phosphatidylcholine 40:7 measurement	NPIPA1 NPIPA2	4.20e-03	13	223	2	EFO_0021477
Disease	Diverticular Diseases	COLQ ISL2	4.20e-03	13	223	2	C4317009
Disease	hypothyroidism (implicated_via_orthology)	DUOX1 DUOX2	4.20e-03	13	223	2	DOID:1459 (implicated_via_orthology)
Disease	Childhood Medulloblastoma	PTCH1 STRADA BRD3	4.21e-03	43	223	3	C0278510
Disease	Melanotic medulloblastoma	PTCH1 STRADA BRD3	4.21e-03	43	223	3	C1275668
Disease	Medullomyoblastoma	PTCH1 STRADA BRD3	4.21e-03	43	223	3	C0205833
Disease	Desmoplastic Medulloblastoma	PTCH1 STRADA BRD3	4.21e-03	43	223	3	C0751291
Disease	Adult Medulloblastoma	PTCH1 STRADA BRD3	4.21e-03	43	223	3	C0278876
Disease	ascending aortic diameter	UNC13D AIG1 MED13L PIEZO2 HYDIN	4.31e-03	140	223	5	EFO_0021787
Disease	granulocyte percentage of myeloid white cells	TBC1D14 CAPN3 BRD3 MED13L LEPR TNFSF13B PRKDC	4.44e-03	268	223	7	EFO_0007997
Disease	stomach cancer (is_marker_for)	ABL1 PTCH1 GDA SLC7A5 ATM	4.57e-03	142	223	5	DOID:10534 (is_marker_for)
Disease	alkaline phosphatase measurement	EMC1 MANBA WDR81 PTCH1 GBGT1 AIG1 MPDU1 ZFP28 MYO1B FCRLA LEPR TNFRSF11B SLC17A1 OASL CDYL2 SENP7	4.68e-03	1015	223	16	EFO_0004533
Disease	Gastric Adenocarcinoma	TRPM7 BRD3 ATM	4.78e-03	45	223	3	C0278701
Disease	Metabolic Bone Disorder	CYP27A1 CTC1	4.87e-03	14	223	2	C0005944
Disease	Childhood Ataxia with Central Nervous System Hypomyelinization	EIF2B5 EIF2B1	4.87e-03	14	223	2	C1858991
Disease	congenital hypothyroidism (implicated_via_orthology)	DUOX1 DUOX2	4.87e-03	14	223	2	DOID:0050328 (implicated_via_orthology)
Disease	hemolysis	PIEZO1 KCNA4 GALNT8	5.41e-03	47	223	3	EFO_0009473
Disease	Osteopenia	CYP27A1 CTC1	5.60e-03	15	223	2	C0029453
Disease	lysophosphatidylethanolamine 18:0 measurement	KBTBD3 ADAMTS16	5.60e-03	15	223	2	EFO_0010367
Disease	Rhabdomyosarcoma	PTCH1 BUB1B	5.60e-03	15	223	2	C0035412
Disease	obesity (implicated_via_orthology)	DCHS2 DEGS2 MED13 CAPN3 MED13L LEPR	6.03e-03	215	223	6	DOID:9970 (implicated_via_orthology)
Disease	cholesteryl ester 20:3 measurement	NPIPA1 NPIPA2 TRMT9B	6.08e-03	49	223	3	EFO_0010347
Disease	autism spectrum disorder (implicated_via_orthology)	NRXN3 NAA16 NAA15 SLC7A5 RIMS2	6.08e-03	152	223	5	DOID:0060041 (implicated_via_orthology)
Disease	Schizoaffective disorder-bipolar type	PTCH1 NRXN3	6.36e-03	16	223	2	EFO_0009965
Disease	Malignant lymphoma, lymphocytic, intermediate differentiation, diffuse	PIK3CD ATM	6.36e-03	16	223	2	C0334634
Disease	Mammary Carcinoma, Human	ABL1 CHEK1 LRRC37A SLC39A6 NQO2 LEPR TCL1B NISCH ATM HADHB	6.92e-03	525	223	10	C4704874
Disease	Mammary Neoplasms, Human	ABL1 CHEK1 LRRC37A SLC39A6 NQO2 LEPR TCL1B NISCH ATM HADHB	6.92e-03	525	223	10	C1257931
Disease	obsolete_red blood cell distribution width	ABL1 PIEZO1 UNC13D F8 KCNA4 TBC1D14 GAL3ST3 OSBP2 DUOX2 BRD3 RFC1 CIT EPG5 TMEM267 FARS2 HSD17B6 SLC7A5 MMAB TUBD1	6.94e-03	1347	223	19	EFO_0005192
Disease	Mammary Neoplasms	ABL1 CHEK1 LRRC37A SLC39A6 NQO2 LEPR TCL1B NISCH ATM HADHB	7.10e-03	527	223	10	C1458155
Disease	Influenza	IFIH1 OAS3 OASL	7.17e-03	52	223	3	C0021400
Disease	muscular dystrophy (is_implicated_in)	MYOT CAPN3	7.18e-03	17	223	2	DOID:9884 (is_implicated_in)
Disease	Antibody Deficiency Syndrome	LEPR EPG5	7.18e-03	17	223	2	C0003257

Protein segments in the cluster

Peptide	Gene	Start	Entry
PIYSLDSWIALKYPG	TMEM184C	91	Q9NVA4
NLVSLWLPVSKPESY	ZNF286A	76	Q9HBT8
VSSQPVPWDFYINLK	BUB1B	796	O60566
PPWLQRYVDKVSNLS	ALKBH6	76	Q3KRA9
EPSNRLPKVYKWSFQ	ARID4B	1206	Q4LE39
FITPNEWLKLPTRYI	FAM228B	206	P0C875
FPSSQVWEKLKQPSY	ERICH6	616	Q7L0X2
LFKELPLYLWQPSAS	EPG5	856	Q9HCE0
AWPFYQPVDAIKLNL	BRD3	56	Q15059
KNPYRFLWGIVTPLA	SLC1A5	331	Q15758
DPIFLYPVVLNWSVK	CFAP54	1306	Q96N23
IYPKLLDNFIPGWLN	AIG1	116	Q9NVV5
VYAVILSSEFWPPFK	ANAPC2	591	Q9UJX6
FLYWPLLESARPVKF	CLSTN3	421	Q9BQT9
VPKPALSFYVLGSWL	CTC1	756	Q2NKJ3
TYLNPWKKIDSAPLA	CHEK1	226	O14757
KFPIKWTAPESLAYN	ABL2	446	P42684
AYQKHPESEWPFLII	ATXN10	206	Q9UBB4
LWYTATNKPRLDFPL	BTBD6	366	Q96KE9
LLSTWYSSKPPLDLA	CALHM3	301	Q86XJ0
KDLPLVSIKSFFQPW	CEP78	66	Q5JTW2
KEPFGLVLIIAPWNY	ALDH3B2	21	P48448
LWGKVFYLDLPSVTI	DBF4	46	Q9UBU7
IWDYFIAKPFLPSSQ	DMXL1	2431	Q9Y485
LYLLAPSFPDKQRWV	CIT	1541	O14578
PNSWLYHAKLLDPST	DCAF16	71	Q9NXF7
YPFKNLPTASKWALR	HADHB	6	P55084
ADYFLRPLPSHLSWK	ADAMTS16	176	Q8TE57
PLLLDNIAKYTEWPT	ARHGEF12	941	Q9NZN5
SGLPYWPYLTAETLK	NPIPB3	226	Q92617
FLLAYVSPEFWLLTK	GPRC5A	256	Q8NFJ5
LEDPHVPASLLKLWY	ARHGAP39	956	Q9C0H5
SLYTPQASKWLLPTV	IQCH	81	Q86VS3
KWRQAFDSYLKTLPP	INTS6L	411	Q5JSJ4
WPYLQKIDPTADTSF	MFSD8	61	Q8NHS3
SGLPYWPYLTAETLK	NPIPA1	226	Q9UND3
GFLYQPQWKIPLFLA	OR5H15	16	A6NDH6
PQWKIPLFLAFLVIY	OR5H15	21	A6NDH6
SGLPYWPYLTAETLK	NPIPB12	226	F8W0I5
GLTYQSEWKIPLFLA	OR5H8	16	P0DN80
SYNPLSKEWISVSPL	KBTBD3	426	Q8NAB2
TDAWSVIASPFLPKY	KLHL30	446	Q0D2K2
YDVPKWLSPSSILLL	MELK	226	Q14680
ASLPFQVANVWPTKY	ANAPC1	171	Q9H1A4
AVYEWLPSFLQKTLP	DUOX1	291	Q9NRD9
GFLYQPQWKIPLFLA	OR5H14	16	A6NHG9
PQWKIPLFLAFLVIY	OR5H14	21	A6NHG9
LYFKDSLGWLPIQLT	COLQ	346	Q9Y215
AFTEYPEWALPLFLL	OR9Q1	16	Q8NGQ5
YWTPQTLPSKETAFL	KANSL1L	581	A0AUZ9
PFLTPYTKINSRWIK	nan	951	O00370
PWSPEKINTRFLLYT	PNLIPRP3	46	Q17RR3
KDFLTISPFSLPFWE	MED13L	1391	Q71F56
QPLWFKDLYKPLSAT	LRRC37A	1646	A6NMS7
PNLAISTLYWKAWPL	INTS1	726	Q8N201
WYQQLPGTAPKLLIY	IGLV1-50	56	A0A075B6I6
SLAPYIIDLPSWTQF	DTX2	71	Q86UW9
SISTLYLLFVWLGPK	ELOVL4	51	Q9GZR5
LNPWYEASLLPIYAV	APH1A	206	Q96BI3
LLIYIKPTNSWIFSP	FUT9	26	Q9Y231
WLPSFLQKTLPEYTG	DUOX2	301	Q9NRD8
LLPLLKAWSPVFRNY	EIF2B5	621	Q13144
PWKLTYRNIGSDFIP	MAP3K8	131	P41279
PWVDYTAPSLITLLF	EIF2B1	271	Q14232
PYLWSFPSNALELVV	FCAR	201	P24071
LDVYGSLPAFLKLWI	SLC7A5P1	121	Q8MH63
FLTKSFWPELPNRID	MMP13	321	P45452
IPGLKATQYWISIPF	OR51F2	31	Q8NH61
YAWPFPIKSLDKFLA	OR4F5	251	Q8NH21
KTYSLLHQWPALYPL	PIK3C2A	926	O00443
DLSNPTKPLELYRQW	PDE4A	591	P27815
EKEPPTTLLWVQYFL	NAA16	366	Q6N069
LIQKWLSYPSGRFPV	HERC4	406	Q5GLZ8
LYPITFPSENAAEWK	GXYLT1	176	Q4G148
FETPEAYISLPKWNT	NRXN3	451	Q9Y4C0
LAWSISPYLAVQLPA	PI4KA	1546	P42356
LEVYGSLPAFLKLWI	SLC7A5	121	Q01650
VWQYESKLEPLPFTS	EVC2	336	Q86UK5
SVPENQYGLPFEKWL	MANSC1	371	Q9H8J5
LYLSPKLWALATPQK	LARP6	191	Q9BRS8
AFNLSYPITPWRFKL	LEPR	21	P48357
SGLPYWPYLTAETLK	NPIPB5	226	A8MRT5
SYKVQWPLHILFTPA	TUBGCP4	456	Q9UGJ1
TPSKLLDPLAWDNHY	F8	1576	P00451
GIKYSLPWTTLDEFP	KCNG1	71	Q9UIX4
LDVYGSLPAFLKLWI	SLC7A5P2	121	Q9GIP4
VSAFKGPYAPWELLS	EGR4	301	Q05215
ESWFPKYIVPSQDLR	IRAK3	541	Q9Y616
YVLIKFANSPRPDLW	LAMA5	156	O15230
SGLPYWPYLTAETLK	NPIPA3	226	F8WFD2
YAWPFPIKSLDKFLA	OR4F17	251	Q8NGA8
WLSYQLLKATEPGLF	PCDHB10	601	Q9UN67
WLSYQLLKATEPGLF	PCDHB15	601	Q9Y5E8
GLPYWPYLTAETLKN	NPIPA2	246	E9PIF3
SGLPYWPYLTAETLK	NPIPB4	226	C9JG80
QFPLYWFSVPAILKG	NQO2	101	P16083
SDLTWPPAIKLGFYA	GPR35	11	Q9HC97
WETPKPFYQLLAEKA	MEIOSIN	616	C9JSJ3
YTPLWFEKRLDPLTG	OSBP2	876	Q969R2
IAQLSIAEWLPSYIP	CASKIN2	546	Q8WXE0
KEEPPTTLLWVQYYL	NAA15	366	Q9BXJ9
WLSYQLLKATEPGLF	PCDHB12	601	Q9Y5F1
FLTLYEWKSPFGLTP	GRIN3A	691	Q8TCU5
PPLYALELLTIYAWE	OASL	231	Q15646
IWYLPRQPNGKITSF	PTPRQ	216	Q9UMZ3
GFLYQPQWKIPLFLA	OR5H1	16	A6NKK0
PQWKIPLFLAFLVIY	OR5H1	21	A6NKK0
SSQRKLNWIPSFPTY	PASD1	16	Q8IV76
YLLSWEPKFQPLASV	DCHS2	3236	Q6V1P9
WLSYQLLKATEPGLF	PCDHB11	601	Q9Y5F2
SGLPYWPYLTAETLK	NPIPB11	226	E5RHQ5
IELAVKYTNHPPALW	OXNAD1	126	Q96HP4
KTLEPKWNQTFIYSP	RIMS2	866	Q9UQ26
WLSYQLLKATEPGLF	PCDHB16	601	Q9NRJ7
LHFLWQTLDYLSPIP	PATL2	96	C9JE40
DWSKLLEPPNFFQKY	PAPOLG	356	Q9BWT3
WLSYQLLKATEPGLF	PCDHB14	601	Q9Y5E9
WLSYQLLKATEPGLF	PCDHB7	601	Q9Y5E2
LSFLELWYTATTIPK	OR6N2	66	Q8NGY6
QGAQLSWYPKLFPLS	GAL3ST3	36	Q96A11
IPYDWEILAKSSLSP	ERVK-10	346	P87889
IPYDWEILAKSSLSP	ERVK-19	346	Q9YNA8
IPYDWEILAKSSLLP	ERVK-21	346	P62683
IPYDWEILAKSSLSP	ERVK-24	346	P63145
IPYDWEILAKSSLSP	ERVK-6	346	Q7LDI9
IPYDWEILAKSSLSP	ERVK-7	346	P63130
IPYDWEILAKSSLSP	ERVK-8	346	P62685
IPYDWEILAKSSLSP	ERVK-9	346	P63126
IPYDWEILAKSSLSP	HERVK_113	346	P62684
WLLSNVLLSTPAPLY	DUOXA2	191	Q1HG44
PWLQIATQLISKYPA	ATM	411	Q13315
VLLYDPLFDWTMNPL	ATM	2951	Q13315
PLFDWTMNPLKALYL	ATM	2956	Q13315
AKILWSFGTLNYKPP	FASTKD5	431	Q7L8L6
YLWEKLDNTLKLPPT	IGSF11	176	Q5DX21
KTPYTELLPITNWLN	HYDIN	4741	Q4G0P3
KYDPKTQEWSFLPSI	KLHL12	301	Q53G59
LADYILTRSWPKPAQ	HSD17B6	301	O14756
WLTSYPSEKFPVSIL	DNAH3	3611	Q8TD57
PWLIQSPSLFANKFE	GCNT7	371	Q6ZNI0
ISNKPSKVLSPEYLW	GBGT1	306	Q8N5D6
SYDWLILQGPAKPVF	FCRLA	76	Q7L513
PSALFQLIDPWKFQR	FNDC11	96	Q9BVV2
VAVNWYAPLVAPISK	GALNT7	306	Q86SF2
TFDWYLKNVYPLLKP	GALNT8	476	Q9NY28
FPLLVPYWEKTFDID	CASQ1	326	P31415
PYWEKTFDIDLSAPQ	CASQ1	331	P31415
SLYATFLPKWTRPVL	CYP27A1	251	Q02318
VSAGLWLLYPKPLFE	CRYBG2	1111	Q8N1P7
KKWVELPITFPNLDY	IFIH1	1001	Q9BYX4
FALWGLKPVVYLLAS	DEGS2	201	Q6QHC5
FPIKWTAPESLAYNK	ABL1	401	P00519
AYVPLIFPATWLLDT	FLVCR1	156	Q9Y5Y0
TKDLDTPTPFWLQYQ	DUXB	266	A0A1W2PPF3
RTILFYPWEPTSKNE	MANBA	851	O00462
KPWAPLQDSEVYLAS	CCDC32	66	Q9BV29
PKVLPSIASYSWLLD	ACOD1	251	A6NK06
DLPLLEWLTKYTFPA	GDA	96	Q9Y2T3
LPELLGKESTWPYLF	SLC2A9	221	Q9NRM0
KAISSAPFLLFQPLW	SLC44A3	321	Q8N4M1
LWKQYLPNVKPDSSF	EMC1	556	Q8N766
PLFEKLGYSQPWIQV	SDR42E2	291	A6NKP2
PLELSFYLLKWLDPQ	FBXW2	61	Q9UKT8
FPVILSAPWYLDLIS	HEXB	441	P07686
PDTFWTNPQYRLKLL	CAPN3	451	P20807
HIPKDLALFTPYEIW	CRLF1	196	O75462
WRNAYKTPLLDDPVF	DHX37	951	Q8IY37
LASYLPSFLRVPKWI	DHRS1	291	Q96LJ7
GIIAPFIPSLKYVQW	SLC22A15	446	Q8IZD6
FIPSLKYVQWSLPFI	SLC22A15	451	Q8IZD6
LPDQLYSLVWFISPI	SLC45A1	151	Q9Y2W3
LPYWPYLTAETLKNR	NPIPB6	246	E9PJ23
KWVLPILTQFTPYLG	PRAMEF26	121	H0Y7S4
YLAAQPRTDLWVYKP	KBTBD6	396	Q86V97
WIDKYTSQLPPLTAF	MMAB	156	Q96EY8
SGLPYWPYLTAETLK	NPIPB13	226	A6NJU9
VTQYPLPNTVKDFWR	PTPRK	1246	Q15262
WFGKPSPLLLQYSVK	PCGF1	241	Q9BSM1
WLSYQLLKATEPGLF	PCDHB3	601	Q9Y5E6
LPPAYALELLTIFAW	OAS3	626	Q9Y6K5
WLSYQLLKATEPGLF	PCDHB9	601	Q9Y5E1
TYQPPWKALSEFALQ	ISL2	296	Q96A47
YAWPFPIKSLDKFLA	OR4F4	251	Q96R69
SGLPYWPYLTAETLK	NPIPA7	226	E9PJI5
SGLPYWPYLTAETLK	NPIPA8	226	P0DM63
FTLFLWSPAEDKKPL	NLE1	351	Q9NVX2
FPLSSYSLNISWEKP	USH2A	1371	O75445
QYSPTPLLKLISIWS	UTP20	1196	O75691
QWIPKPVLYGLFLYI	SLC4A11	761	Q8NBS3
LSYPLSWVQAFPLFQ	SENP7	651	Q9BQF6
YSVKVLPWLSPEVLQ	STRADA	236	Q7RTN6
ELAYRPPLWEQSAKL	SPATA2L	256	Q8IUW3
SLYKLVGSPPWKEAF	RPAIN	11	Q86UA6
FNLSTYLIPRHWIPK	TDO2	366	P48775
SLYSWPVPESALFIL	LRRC41	231	Q15345
NPIFLPSDAKYDWLL	ALOX5	336	P09917
WYQQLPGTAPKLLIY	IGLV1-40	56	P01703
RIPWSEFFDLPSLNK	POFUT2	101	Q9Y2G5
SGLPYWPYLTAETLK	NPIPA5	226	E9PKD4
KTFWRYNLSQPSEAP	RFX1	636	P22670
WSLLPAQAIYASVLP	RFC1	931	P35251
ATLDDDKPWYSIFPI	TAF1	456	P21675
PSSVFWSLLKNLPFL	FBXL18	471	Q96ME1
ATAQFEIYVKWAPPL	SLC17A1	151	Q14916
AYLLGKPPLRWTNFD	PTCH1	246	Q13635
LPLVASWKTYPLFFG	SLC36A2	256	Q495M3
AIQFWLLYAPPKEKD	TBATA	246	Q96M53
LIPKAKPLTLLWAYF	SCD5	66	Q86SK9
PAFLAFAWALKYLPK	CCT8L2	436	Q96SF2
PLLVKPLFNLVSWAF	RDH14	261	Q9HBH5
PLFNLVSWAFFKTPV	RDH14	266	Q9HBH5
PVDAKSPYFLSQLWT	ARHGAP5	636	Q13017
SPYFLSQLWTAAFKP	ARHGAP5	641	Q13017
SLFPIASWLPAYRLK	SLC26A3	56	P40879
KKYVWQGPTSAPILF	MED13	31	Q9UHV7
SYQPPWKVLSDFALQ	ISL1	286	P61371
SYWTKLLSQLLAPLP	PPP1R15B	61	Q5SWA1
DAKLLWLPASYLPAS	RDH5	286	Q92781
LDLTPTILDWFSIPY	SGSH	316	P51688
LIAAQLLFYWNAKPP	MPDU1	226	O75352
IPYDWEILAKSSLSP	ERVK-9	346	P63128
KAEIPPKTYSLQIAW	SLC39A6	311	Q13433
TSWKVKYPFIPLLLT	ALG8	481	Q9BVK2
KAWFQTPYATIRLTP	CDYL2	376	Q8N8U2
LDAWLAKYPPSQVTR	C11orf68	91	Q9H3H3
WIFTLYSKSLPLDLA	TBC1D14	586	Q9P2M4
FKDPALYTSWLKPVN	TUBD1	361	Q9UJT1
AAWAKVPPQLIFSSF	TIGD3	346	Q6B0B8
PVDLFPKFLWNPSSL	ZFP28	851	Q8NHY6
IKWTTQETFPPKYLH	TNFRSF11B	16	O00300
EYDALLPWPFKQKVT	TRAF3	481	Q13114
PFSSEVFTLWYNLLP	WWC2	811	Q6AWC2
YFVLLLTPWLEFSKS	XKRY	81	O14609
LPSYKRTPTEWIQDF	THEM4	76	Q5T1C6
VKSAAIPYWLLLTPQ	NISCH	901	Q9Y2I1
KSLLYSAPIDPTEWV	PIEZO2	1031	Q9H5I5
AWLQYSFPLQLEPSA	PIK3CD	161	O00329
NSFLWTIKRDPPSYF	TRABD2A	41	Q86V40
PYEDLKTKLNSPWRT	TBC1D30	716	Q9Y2I9
KPWLLEVNYSPALTL	TTLL2	381	Q9BWV7
VWYESTLKLQPEFVP	TTC17	1106	Q96AE7
FSQLPAVWQLYPGRK	TCL1B	81	O95988
WEDLILYSIDKPPFI	VPS41	696	P49754
SGLPYWPYLTAETLK	NPIPB2	241	A6NJ64
VFRPYAKHWLSPLLQ	PRKDC	2156	P78527
FNKFPYPTQAELSWL	ZHX2	281	Q9Y6X8
YFVLLLTPWLEFSKS	XKRY2	81	A2RUG3
FPYPLQWSLLVAVVA	TMEM141	56	Q96I45
FWYVEYPSKPLQLLQ	TRAV40	51	A0A0B4J280
IDPILYTWLIYQPQK	VPS13B	956	Q7Z7G8
APYFSDLQSKAWPRV	TRMT9B	21	Q9P272
LPSFWIKAKNDYPEL	ZBED9	1246	Q6R2W3
KWHLLSELEAAPYLP	GTF3C2	336	Q8WUA4
LIKWLYLPDFFRAPN	PIEZO1	1081	Q92508
TFRIFIPLLPHSWKY	ZDHHC11B	56	P0C7U3
TYFPKWSVISLLRQP	TCTN3	216	Q6NUS6
DFGKETQWPLLLPYS	TGM7	556	Q96PF1
PTIQKGSYTFVPWLL	TNFSF13B	156	Q9Y275
PLSKYPAVINDISFW	FARS2	356	O95363
FPIQVIKWRPSDDYL	WDR7	561	Q9Y4E6
PAIPSWLQKTYNEAL	UNC13D	591	Q70J99
GKTSPLPFWLYVIIT	TMEM267	171	Q0VDI3
NSWYKVILSILVPPA	TRPM7	756	Q96QT4
TAWYLFEPVAKALGP	WDR81	941	Q562E7
TYARDKWLPSDPQII	TRPC3	511	Q13507
SAPYWLINKTGLPLI	VPS13D	3281	Q5THJ4
VGYQLFKPSLISWLE	ZNF266	11	Q14584
KQIWLLFEYPESSSP	KCNA4	291	P22459
DKNWPSRPYLFLDST	MYO1B	896	O43795
FKVSGLPAPDVSWYL	MYOT	271	Q9UBF9