Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionacetylcholine receptor regulator activity

SPDYE1 SPDYE11 SPDYE7P SPDYE3 SPDYE2 SPDYE5 SPDYE2B SPDYE4 SPDYE6 SPDYE16

8.99e-18278510GO:0030548
GeneOntologyMolecularFunctionneurotransmitter receptor regulator activity

SPDYE1 SPDYE11 SPDYE7P SPDYE3 SPDYE2 SPDYE5 SPDYE2B SPDYE4 SPDYE6 SPDYE16

1.39e-17288510GO:0099602
GeneOntologyMolecularFunctionprotein kinase binding

SPDYE1 SPDYE11 SPDYE17 SPDYE10 BRAF SPDYE15 SPDYE7P SPDYE3 SPDYE2 SPDYE8 GRIA1 SPDYE21 SPDYE5 SPDYE18 RAPGEF2 SPDYE12 SPDYE2B SPDYE4 RAB13 SPDYE6 ADD2 SPDYE14 SPDYE16

1.08e-128738523GO:0019901
GeneOntologyMolecularFunctionkinase binding

PRPSAP1 SPDYE1 SPDYE11 SPDYE17 SPDYE10 BRAF SPDYE15 SPDYE7P SPDYE3 SPDYE2 SPDYE8 GRIA1 SPDYE21 SPDYE5 SPDYE18 RAPGEF2 SPDYE12 SPDYE2B SPDYE4 RAB13 SPDYE6 ADD2 SPDYE14 SPDYE16

1.16e-129698524GO:0019900
GeneOntologyMolecularFunctionsignaling receptor regulator activity

SPDYE1 SPDYE11 SPDYE7P SPDYE3 SPDYE2 SPDYE5 SPDYE2B SPDYE4 DKK2 SPDYE6 SPDYE16

5.93e-056168511GO:0030545
GeneOntologyMolecularFunctionribose phosphate diphosphokinase activity

PRPSAP1 PRPSAP2

1.78e-045852GO:0004749
GeneOntologyMolecularFunctiondiphosphotransferase activity

PRPSAP1 PRPSAP2

2.66e-046852GO:0016778
GeneOntologyBiologicalProcesspositive regulation of cyclin-dependent protein serine/threonine kinase activity

SPDYE1 SPDYE7P SPDYE3 SPDYE2 SPDYE5 SPDYE2B SPDYE4 SPDYE6 SPDYE16

1.49e-1625769GO:0045737
GeneOntologyBiologicalProcesspositive regulation of cyclin-dependent protein kinase activity

SPDYE1 SPDYE7P SPDYE3 SPDYE2 SPDYE5 SPDYE2B SPDYE4 SPDYE6 SPDYE16

5.01e-1628769GO:1904031
GeneOntologyBiologicalProcessregulation of cyclin-dependent protein serine/threonine kinase activity

SPDYE1 GTPBP4 SPDYE7P SPDYE3 SPDYE2 SPDYE5 SPDYE2B SPDYE4 NR2F2 SPDYE6 SPDYE16

5.50e-14967611GO:0000079
GeneOntologyBiologicalProcessregulation of cyclin-dependent protein kinase activity

SPDYE1 GTPBP4 SPDYE7P SPDYE3 SPDYE2 SPDYE5 SPDYE2B SPDYE4 NR2F2 SPDYE6 SPDYE16

8.73e-141007611GO:1904029
GeneOntologyBiologicalProcesspositive regulation of protein serine/threonine kinase activity

SPDYE1 SPDYE7P SPDYE3 SPDYE2 SPDYE5 RAPGEF2 SPDYE2B SPDYE4 SPDYE6 SPDYE16

2.28e-091937610GO:0071902
GeneOntologyBiologicalProcessregulation of protein serine/threonine kinase activity

SPDYE1 GTPBP4 SPDYE7P SPDYE3 SPDYE2 SPDYE5 RAPGEF2 SPDYE2B SPDYE4 NR2F2 SPDYE6 SPDYE16

7.12e-093587612GO:0071900
GeneOntologyBiologicalProcessregulation of protein kinase activity

SPDYE1 GTPBP4 SPDYE7P TSPYL2 SPDYE3 SPDYE2 SPDYE5 RAPGEF2 SPDYE2B SPDYE4 NR2F2 SPDYE6 SPDYE16

3.28e-076117613GO:0045859
GeneOntologyBiologicalProcesspositive regulation of protein kinase activity

SPDYE1 SPDYE7P SPDYE3 SPDYE2 SPDYE5 RAPGEF2 SPDYE2B SPDYE4 SPDYE6 SPDYE16

6.15e-073507610GO:0045860
GeneOntologyBiologicalProcessregulation of kinase activity

SPDYE1 GTPBP4 SPDYE7P TSPYL2 SPDYE3 SPDYE2 SPDYE5 RAPGEF2 SPDYE2B SPDYE4 NR2F2 SPDYE6 SPDYE16

1.21e-066867613GO:0043549
GeneOntologyBiologicalProcessregulation of transferase activity

SPDYE1 GTPBP4 SPDYE7P TSPYL2 SPDYE3 SPDYE2 PUM3 SPDYE5 RAPGEF2 SPDYE2B SPDYE4 NR2F2 SPDYE6 SPDYE16

1.33e-068107614GO:0051338
GeneOntologyBiologicalProcesspositive regulation of kinase activity

SPDYE1 SPDYE7P SPDYE3 SPDYE2 SPDYE5 RAPGEF2 SPDYE2B SPDYE4 SPDYE6 SPDYE16

2.29e-064057610GO:0033674
GeneOntologyBiologicalProcesspositive regulation of cell cycle

SPDYE1 SPDYE7P ASNS SPDYE3 SPDYE2 SPDYE5 SPDYE2B SPDYE4 SPDYE6 SPDYE16

2.40e-064077610GO:0045787
GeneOntologyBiologicalProcesspositive regulation of transferase activity

SPDYE1 SPDYE7P SPDYE3 SPDYE2 SPDYE5 RAPGEF2 SPDYE2B SPDYE4 SPDYE6 SPDYE16

1.23e-054907610GO:0051347
GeneOntologyBiologicalProcesspositive regulation of protein phosphorylation

FNIP2 SPDYE1 BRAF SPDYE7P SPDYE3 SPDYE2 SPDYE5 RAPGEF2 SPDYE2B SPDYE4 SPDYE6 SPDYE16

1.26e-057247612GO:0001934
GeneOntologyBiologicalProcessregulation of protein phosphorylation

FNIP2 SPDYE1 GTPBP4 BRAF SPDYE7P TSPYL2 SPDYE3 SPDYE2 SPDYE5 RAPGEF2 SPDYE2B SPDYE4 NR2F2 SPDYE6 SPDYE16

1.37e-0511337615GO:0001932
GeneOntologyBiologicalProcesspositive regulation of phosphorylation

FNIP2 SPDYE1 BRAF SPDYE7P SPDYE3 SPDYE2 SPDYE5 RAPGEF2 SPDYE2B SPDYE4 SPDYE6 SPDYE16

2.64e-057807612GO:0042327
GeneOntologyBiologicalProcessregulation of phosphorylation

FNIP2 SPDYE1 GTPBP4 BRAF SPDYE7P TSPYL2 SPDYE3 SPDYE2 SPDYE5 RAPGEF2 SPDYE2B SPDYE4 NR2F2 SPDYE6 SPDYE16

3.45e-0512267615GO:0042325
GeneOntologyBiologicalProcessregulation of cell cycle

SPDYE1 GTPBP4 CCNDBP1 SPDYE7P MAEA ASNS TSPYL2 SPDYE3 SPDYE2 SPDYE5 SPDYE2B SPDYE4 NR2F2 SPDYE6 SPDYE16

4.56e-0512567615GO:0051726
GeneOntologyBiologicalProcesspositive regulation of phosphate metabolic process

FNIP2 SPDYE1 BRAF SPDYE7P SPDYE3 SPDYE2 SPDYE5 RAPGEF2 SPDYE2B SPDYE4 SPDYE6 SPDYE16

8.37e-058797612GO:0045937
GeneOntologyBiologicalProcesspositive regulation of phosphorus metabolic process

FNIP2 SPDYE1 BRAF SPDYE7P SPDYE3 SPDYE2 SPDYE5 RAPGEF2 SPDYE2B SPDYE4 SPDYE6 SPDYE16

8.37e-058797612GO:0010562
GeneOntologyBiologicalProcesspositive regulation of protein modification process

FNIP2 SPDYE1 BRAF SPDYE7P SPDYE3 SPDYE2 SPDYE5 RAPGEF2 SPDYE2B SPDYE4 SPDYE6 SPDYE16

1.53e-049377612GO:0031401
GeneOntologyBiologicalProcessregulation of phosphate metabolic process

FNIP2 SPDYE1 GTPBP4 BRAF SPDYE7P TSPYL2 SPDYE3 SPDYE2 SPDYE5 RAPGEF2 SPDYE2B SPDYE4 NR2F2 SPDYE6 SPDYE16

1.82e-0414217615GO:0019220
GeneOntologyBiologicalProcessregulation of phosphorus metabolic process

FNIP2 SPDYE1 GTPBP4 BRAF SPDYE7P TSPYL2 SPDYE3 SPDYE2 SPDYE5 RAPGEF2 SPDYE2B SPDYE4 NR2F2 SPDYE6 SPDYE16

1.85e-0414237615GO:0051174
GeneOntologyBiologicalProcess5-phosphoribose 1-diphosphate biosynthetic process

PRPSAP1 PRPSAP2

1.99e-046762GO:0006015
GeneOntologyBiologicalProcess5-phosphoribose 1-diphosphate metabolic process

PRPSAP1 PRPSAP2

1.99e-046762GO:0046391
GeneOntologyBiologicalProcessregulation of protein modification process

FNIP2 SPDYE1 GTPBP4 BRAF SPDYE7P TSPYL2 SPDYE3 SPDYE2 SPDYE5 RAPGEF2 SPDYE2B SPDYE4 NR2F2 SPDYE6 SPDYE16

3.00e-0414887615GO:0031399
GeneOntologyBiologicalProcessresponse to purine-containing compound

THBD BRAF ATF1 RAPGEF2 CREB1

3.70e-04166765GO:0014074
GeneOntologyBiologicalProcessinhibition of non-skeletal tissue mineralization

ATF1 CREB1

5.92e-0410762GO:0140928
GeneOntologyBiologicalProcessregulation of calcium ion-dependent exocytosis

SYT9 POU5F1B SYT10

6.10e-0445763GO:0017158
GeneOntologyCellularComponentATF4-CREB1 transcription factor complex

ATF1 CREB1

7.79e-054762GO:1990589
GeneOntologyCellularComponentribose phosphate diphosphokinase complex

PRPSAP1 PRPSAP2

1.30e-045762GO:0002189
DomainSpy1

SPDYE1 SPDYE3 SPDYE2 SPDYE21 SPDYE5 SPDYE2B SPDYE4 SPDYE6 SPDYE16

7.94e-2111749PF11357
DomainSpeedy

SPDYE1 SPDYE3 SPDYE2 SPDYE21 SPDYE5 SPDYE2B SPDYE4 SPDYE6 SPDYE16

7.94e-2111749IPR020984
DomainCOUP_TF

NR2F6 NR2F1 NR2F2

5.94e-075743IPR003068
DomainKID

ATF1 CREB1

4.63e-053742PS50953
DomainCoactivator_CBP_pKID

ATF1 CREB1

4.63e-053742IPR003102
DomainpKID

ATF1 CREB1

4.63e-053742PF02173
DomainLeuzip_CREB

ATF1 CREB1

9.24e-054742IPR001630
DomainRib-P_diPkinase

PRPSAP1 PRPSAP2

1.54e-045742IPR005946
DomainPribosyltran_N

PRPSAP1 PRPSAP2

1.54e-045742IPR029099
DomainPribosyltran_N

PRPSAP1 PRPSAP2

1.54e-045742PF13793
DomainPribosyl_synth

PRPSAP1 PRPSAP2

1.54e-045742PF14572
Domainzf-C4

NR2F6 NR2F1 NR2F2

8.02e-0446743PF00105
DomainZnf_hrmn_rcpt

NR2F6 NR2F1 NR2F2

8.02e-0446743IPR001628
DomainNuclear_hrmn_rcpt

NR2F6 NR2F1 NR2F2

8.02e-0446743IPR001723
DomainNUCLEAR_REC_DBD_2

NR2F6 NR2F1 NR2F2

8.02e-0446743PS51030
DomainNUCLEAR_REC_DBD_1

NR2F6 NR2F1 NR2F2

8.02e-0446743PS00031
DomainZnF_C4

NR2F6 NR2F1 NR2F2

8.02e-0446743SM00399
DomainPribosyltran

PRPSAP1 PRPSAP2

8.32e-0411742PF00156
Domain-

NR2F6 NR2F1 NR2F2

8.54e-04477431.10.565.10
DomainHOLI

NR2F6 NR2F1 NR2F2

9.09e-0448743SM00430
DomainNucl_hrmn_rcpt_lig-bd

NR2F6 NR2F1 NR2F2

9.09e-0448743IPR000536
DomainHormone_recep

NR2F6 NR2F1 NR2F2

9.09e-0448743PF00104
DomainPRTase-like

PRPSAP1 PRPSAP2

9.96e-0412742IPR029057
DomainPRibTrfase_dom

PRPSAP1 PRPSAP2

9.96e-0412742IPR000836
Domain-

PRPSAP1 PRPSAP2

9.96e-04127423.40.50.2020
Domain-

NR2F6 NR2F1 NR2F2

1.50e-03577433.30.50.10
DomainZnf_NHR/GATA

NR2F6 NR2F1 NR2F2

1.58e-0358743IPR013088
DomainRasGEFN

RAPGEF2 SOS1

2.81e-0320742SM00229
DomainSynaptotagmin

SYT9 SYT10

2.81e-0320742IPR001565
DomainRasGEF_N

RAPGEF2 SOS1

3.10e-0321742PF00618
DomainRas-like_Gua-exchang_fac_N

RAPGEF2 SOS1

3.40e-0322742IPR000651
DomainRASGEF_NTER

RAPGEF2 SOS1

3.40e-0322742PS50212
DomaincEGF

THBD SCUBE3

4.73e-0326742IPR026823
DomaincEGF

THBD SCUBE3

4.73e-0326742PF12662
DomainRASGEF_CAT

RAPGEF2 SOS1

5.87e-0329742PS50009
DomainRasGEF

RAPGEF2 SOS1

6.27e-0330742PF00617
Domain-

RAPGEF2 SOS1

6.27e-03307421.10.840.10
DomainRas_GEF_dom

RAPGEF2 SOS1

6.27e-0330742IPR023578
DomainRASGEF_cat_dom

RAPGEF2 SOS1

6.27e-0330742IPR001895
DomainRasGEF

RAPGEF2 SOS1

6.27e-0330742SM00147
PathwayREACTOME_SIGNALING_BY_NTRK1_TRKA

BRAF ATF1 CHD4 CREB1 SOS1

2.49e-0663495MM14714
PathwayREACTOME_SIGNALING_BY_NTRKS

BRAF ATF1 CHD4 CREB1 SOS1

5.92e-0675495MM14652
PathwayWP_SEROTONIN_RECEPTOR_467_AND_NR3C_SIGNALING

BRAF ATF1 CREB1

3.68e-0519493M39358
PathwayWP_MECHANISMS_ASSOCIATED_WITH_PLURIPOTENCY

NR2F6 CHD4 POU5F1B CREB1 NR2F1 NR2F2 SOS1

7.51e-05301497MM15983
PathwayREACTOME_SIGNALING_BY_NTRKS

BRAF ATF1 CHD4 CREB1 SOS1

9.82e-05134495M3574
PathwayREACTOME_NUCLEAR_EVENTS_KINASE_AND_TRANSCRIPTION_FACTOR_ACTIVATION

ATF1 CHD4 CREB1

1.09e-0427493MM14779
PathwayWP_ESTROGEN_SIGNALING

BRAF TAF13 CREB1 SOS1

1.45e-0477494MM15934
PathwayWP_PILOCYTIC_ASTROCYTOMA

BRAF SOS1

1.76e-046492M39584
PathwayREACTOME_NGF_STIMULATED_TRANSCRIPTION

CHD4 CREB1

1.76e-046492MM15627
PathwayWP_BDNFTRKB_SIGNALING

BRAF CREB1 SOS1

2.00e-0433493M39532
PathwayBIOCARTA_HBX_PATHWAY

CREB1 SOS1

2.46e-047492M22037
PathwayBIOCARTA_HBX_PATHWAY

CREB1 SOS1

2.46e-047492MM1557
PathwayREACTOME_CREB_PHOSPHORYLATION

ATF1 CREB1

2.46e-047492M27096
PathwayREACTOME_CREB_PHOSPHORYLATION

ATF1 CREB1

2.46e-047492MM14784
PathwayWP_NUCLEAR_RECEPTORS

NR2F6 NR2F1 NR2F2

3.06e-0438493M39657
PathwayWP_NUCLEAR_RECEPTORS

NR2F6 NR2F1 NR2F2

3.06e-0438493MM15865
PathwayREACTOME_NGF_STIMULATED_TRANSCRIPTION

ATF1 CHD4 CREB1

3.30e-0439493M29793
PathwayPID_ERBB1_DOWNSTREAM_PATHWAY

BRAF ATF1 CREB1 SOS1

4.76e-04105494M164
PathwayKEGG_ENDOMETRIAL_CANCER

BRAF CTNNA3 SOS1

7.74e-0452493M19877
PathwayWP_FRAGILE_X_SYNDROME

BRAF GRIA1 CREB1 SOS1

8.12e-04121494M39804
PathwayKEGG_MEDICUS_VARIANT_BCR_ABL_FUSION_KINASE_TO_RAS_ERK_SIGNALING_PATHWAY

BRAF SOS1

1.05e-0314492M47364
PathwayKEGG_MEDICUS_VARIANT_MUTATION_ACTIVATED_KIT_TO_RAS_ERK_SIGNALING_PATHWAY

BRAF SOS1

1.05e-0314492M47365
PathwayKEGG_MEDICUS_VARIANT_DUPLICATION_OR_MUTATION_ACTIVATED_FLT3_TO_RAS_ERK_SIGNALING_PATHWAY

BRAF SOS1

1.05e-0314492M47366
PathwayKEGG_MEDICUS_VARIANT_AMPLIFIED_PDGFR_TO_RAS_ERK_SIGNALING_PATHWAY

BRAF SOS1

1.05e-0314492M47378
PathwayKEGG_MEDICUS_VARIANT_MET_OVEREXPRESSION_TO_RAS_ERK_SIGNALING_PATHWAY

BRAF SOS1

1.05e-0314492M47488
PathwayKEGG_MEDICUS_VARIANT_MUTATION_ACTIVATED_MET_TO_RAS_ERK_SIGNALING_PATHWAY

BRAF SOS1

1.21e-0315492M47367
PathwayKEGG_MEDICUS_VARIANT_MUTATION_ACTIVATED_EGFR_TO_RAS_ERK_SIGNALING_PATHWAY

BRAF SOS1

1.21e-0315492M47375
PathwayKEGG_MEDICUS_VARIANT_AMPLIFIED_FGFR_TO_RAS_ERK_SIGNALING_PATHWAY

BRAF SOS1

1.21e-0315492M47380
PathwayKEGG_MEDICUS_REFERENCE_CA2_PYK2_RAS_ERK_SIGNALING_PATHWAY

BRAF SOS1

1.21e-0315492M47592
PathwayKEGG_MEDICUS_PATHOGEN_HBV_HBX_TO_RAS_ERK_SIGNALING_PATHWAY

BRAF SOS1

1.21e-0315492M47593
PathwayKEGG_MEDICUS_VARIANT_MUTATION_INACTIVATED_FGF17_TO_RAS_ERK_SIGNALING_PATHWAY

BRAF SOS1

1.21e-0315492M47640
PathwayKEGG_MEDICUS_VARIANT_IGF2_OVEREXPRESSION_TO_RAS_ERK_SIGNALING_PATHWAY

BRAF SOS1

1.21e-0315492M47485
PathwayKEGG_MEDICUS_REFERENCE_HGF_MET_RAS_ERK_SIGNALING_PATHWAY

BRAF SOS1

1.21e-0315492M47473
PathwayKEGG_MEDICUS_REFERENCE_FLT3LG_FLT3_RAS_ERK_SIGNALING_PATHWAY

BRAF SOS1

1.21e-0315492M47474
PathwayKEGG_MEDICUS_REFERENCE_TGFA_EGFR_RAS_ERK_SIGNALING_PATHWAY

BRAF SOS1

1.21e-0315492M47480
PathwayKEGG_MEDICUS_VARIANT_EGF_OVEREXPRESSION_TO_RAS_ERK_SIGNALING_PATHWAY

BRAF SOS1

1.21e-0315492M47495
PathwayKEGG_MEDICUS_REFERENCE_EREG_EGFR_RAS_ERK_SIGNALING_PATHWAY

BRAF SOS1

1.21e-0315492M47496
PathwayKEGG_MEDICUS_REFERENCE_AREG_EGFR_RAS_ERK_SIGNALING_PATHWAY

BRAF SOS1

1.21e-0315492M47497
PathwayKEGG_MEDICUS_REFERENCE_KITLG_KIT_RAS_ERK_SIGNALING_PATHWAY

BRAF SOS1

1.21e-0315492M47472
PathwayKEGG_MEDICUS_PATHOGEN_HCMV_GB_TO_PDGFR_RAS_ERK_SIGNALING_PATHWAY

BRAF SOS1

1.21e-0315492M47535
PathwayKEGG_MEDICUS_PATHOGEN_HPV_E5_TO_EGFR_RAS_ERK_SIGNALING_PATHWAY

BRAF SOS1

1.21e-0315492M47531
PathwayREACTOME_NUCLEAR_EVENTS_KINASE_AND_TRANSCRIPTION_FACTOR_ACTIVATION

ATF1 CHD4 CREB1

1.23e-0361493M152
PathwayWP_ENDOMETRIAL_CANCER

BRAF CTNNA3 SOS1

1.35e-0363493M39623
PathwayKEGG_MEDICUS_REFERENCE_EGF_EGFR_RAS_ERK_SIGNALING_PATHWAY

BRAF SOS1

1.38e-0316492M47363
PathwayKEGG_MEDICUS_VARIANT_MUTATION_ACTIVATED_FGFR3_TO_RAS_ERK_SIGNALING_PATHWAY

BRAF SOS1

1.38e-0316492M47373
PathwayKEGG_MEDICUS_REFERENCE_EGF_ERBB2_RAS_ERK_SIGNALING_PATHWAY

BRAF SOS1

1.38e-0316492M47381
PathwayKEGG_MEDICUS_REFERENCE_P4_PR_RAS_ERK_SIGNALING_PATHWAY

BRAF SOS1

1.38e-0316492M47804
PathwayWP_MAPK_PATHWAY_IN_CONGENITAL_THYROID_CANCER

BRAF SOS1

1.38e-0316492M39882
PathwayKEGG_MEDICUS_REFERENCE_IGF_IGF1R_RAS_ERK_SIGNALING_PATHWAY

BRAF SOS1

1.38e-0316492M47483
PathwayREACTOME_GASTRIN_CREB_SIGNALLING_PATHWAY_VIA_PKC_AND_MAPK

CREB1 SOS1

1.38e-0316492MM15477
PathwayKEGG_MEDICUS_REFERENCE_PDGF_PDGFR_RAS_ERK_SIGNALING_PATHWAY

BRAF SOS1

1.56e-0317492M47376
PathwayWP_MELANOMA

BRAF CREB1 SOS1

1.69e-0368493M39811
PathwayREACTOME_GASTRIN_CREB_SIGNALLING_PATHWAY_VIA_PKC_AND_MAPK

CREB1 SOS1

1.75e-0318492M657
PathwayBIOCARTA_CREB_PATHWAY

CREB1 SOS1

2.16e-0320492MM1520
PathwayWP_EGFEGFR_SIGNALING

BRAF ATF1 CREB1 SOS1

2.38e-03162494M39334
PathwayKEGG_MEDICUS_REFERENCE_ACH_CHRN_RAS_ERK_SIGNALING_PATHWAY

BRAF CREB1

2.38e-0321492M47792
PathwayBIOCARTA_CREB_PATHWAY

CREB1 SOS1

2.62e-0322492M9070
PathwayKEGG_MEDICUS_REFERENCE_E2_ER_RAS_ERK_SIGNALING_PATHWAY

BRAF CREB1

2.86e-0323492M47799
PathwayREACTOME_RNA_POLYMERASE_III_TRANSCRIPTION_TERMINATION

NFIA POLR1C

2.86e-0323492M1024
PathwayWP_ESTROGEN_SIGNALING

BRAF CREB1

2.86e-0323492M39672
Pubmed

Identification and comparative analysis of multiple mammalian Speedy/Ringo proteins.

SPDYE1 SPDYE17 SPDYE7P SPDYE3 SPDYE2 SPDYE5 SPDYE2B SPDYE4 SPDYE6 SPDYE16

1.25e-2413851015611625
Pubmed

Murine fertility and spermatogenesis are independent of the testis-specific Spdye4a gene.

SPDYE1 SPDYE7P SPDYE3 SPDYE2 SPDYE5 SPDYE2B SPDYE4 SPDYE6 SPDYE16

2.01e-24985936272447
Pubmed

Characterization of a new family of cyclin-dependent kinase activators.

SPDYE1 SPDYE17 SPDYE7P SPDYE3 SPDYE2 SPDYE5 SPDYE2B SPDYE4 SPDYE6 SPDYE16

8.42e-2317851015574121
Pubmed

Evolution of the Cdk-activator Speedy/RINGO in vertebrates.

SPDYE17 SPDYE2 SPDYE6

1.41e-08385322763696
Pubmed

The nuclear orphan receptor NR2F6 suppresses lymphocyte activation and T helper 17-dependent autoimmunity.

NR2F6 NR2F1 NR2F2

1.41e-08385318701084
Pubmed

Activating transcription factor 1 and CREB are important for cell survival during early mouse development.

ATF1 POU5F1B CREB1

2.80e-07685311865068
Pubmed

Cloning and expression during development of three murine members of the COUP family of nuclear orphan receptors.

NR2F6 NR2F1 NR2F2

2.80e-0768537947324
Pubmed

A dynamic balance between ARP-1/COUP-TFII, EAR-3/COUP-TFI, and retinoic acid receptor:retinoid X receptor heterodimers regulates Oct-3/4 expression in embryonal carcinoma cells.

POU5F1B NR2F1 NR2F2

1.17e-0698537823919
Pubmed

COUP-TFI and -TFII nuclear receptors are expressed in amacrine cells and play roles in regulating the differentiation of retinal progenitor cells.

NR2F1 NR2F2

5.90e-06285219766631
Pubmed

Neurogenic transdifferentiation of human adipose-derived stem cells? A critical protocol reevaluation with special emphasis on cell proliferation and cell cycle alterations.

ATF1 CREB1

5.90e-06285220945072
Pubmed

CREB function is required for normal thymic cellularity and post-irradiation recovery.

ATF1 CREB1

5.90e-06285215214044
Pubmed

Reversible inhibition of CREB/ATF transcription factors in region CA1 of the dorsal hippocampus disrupts hippocampus-dependent spatial memory.

ATF1 CREB1

5.90e-06285211988175
Pubmed

Novel NR2F1 variants likely disrupt DNA binding: molecular modeling in two cases, review of published cases, genotype-phenotype correlation, and phenotypic expansion of the Bosch-Boonstra-Schaaf optic atrophy syndrome.

NR2F1 NR2F2

5.90e-06285228963436
Pubmed

CREB is necessary for synaptic maintenance and learning-induced changes of the AMPA receptor GluA1 subunit.

GRIA1 CREB1

5.90e-06285223504989
Pubmed

An evolutionary conserved COUP-TF binding element in a neural-specific gene and COUP-TF expression patterns support a major role for COUP-TF in neural development.

NR2F1 NR2F2

5.90e-0628527708064
Pubmed

Chicken ovalbumin upstream promoter transcription factor (COUP-TF): expression during mouse embryogenesis.

NR2F1 NR2F2

5.90e-0628527626501
Pubmed

Spatiotemporal expression patterns of chicken ovalbumin upstream promoter-transcription factors in the developing mouse central nervous system: evidence for a role in segmental patterning of the diencephalon.

NR2F1 NR2F2

5.90e-0628528183930
Pubmed

Localization of transcripts of the related nuclear orphan receptors COUP-TF I and ARP-1 in the adult mouse brain.

NR2F1 NR2F2

5.90e-0628527609634
Pubmed

Identification of two novel members of erbA superfamily by molecular cloning: the gene products of the two are highly related to each other.

NR2F6 NR2F1

5.90e-0628522905047
Pubmed

Dynamic expression of COUP-TFI and COUP-TFII during development and functional maturation of the mouse inner ear.

NR2F1 NR2F2

5.90e-06285215907456
Pubmed

Requirement for COUP-TFI and II in the temporal specification of neural stem cells in CNS development.

NR2F1 NR2F2

5.90e-06285219160499
Pubmed

All-trans retinoic acid affects the expression of orphan receptors COUP-TF I and COUP-TF II in the developing neural tube.

NR2F1 NR2F2

5.90e-0628528804707
Pubmed

CDK activation by non-cyclin proteins.

SPDYE17 SPDYE6

5.90e-06285216488127
Pubmed

Analysis of the oncogene BRAF mutation and the correlation of the expression of wild-type BRAF and CREB1 in endometriosis.

BRAF CREB1

5.90e-06285229286077
Pubmed

Depletion of cAMP-response element-binding protein/ATF1 inhibits adipogenic conversion of 3T3-L1 cells ectopically expressing CCAAT/enhancer-binding protein (C/EBP) alpha, C/EBP beta, or PPAR gamma 2.

ATF1 CREB1

5.90e-06285217071615
Pubmed

Established and novel Cdk/cyclin complexes regulating the cell cycle and development.

SPDYE17 SPDYE6

5.90e-06285221630153
Pubmed

The Transcription Factors COUP-TFI and COUP-TFII have Distinct Roles in Arealisation and GABAergic Interneuron Specification in the Early Human Fetal Telencephalon.

NR2F1 NR2F2

5.90e-06285228922831
Pubmed

The DNA sequence of human chromosome 7.

BRAF ASNS SPDYE3 SPDYE21 SPDYE5 SPDYE2B SPDYE6 SPDYE16

1.29e-0544185812853948
Pubmed

Detection and characterization of EWSR1/ATF1 and EWSR1/CREB1 chimeric transcripts in clear cell sarcoma (melanoma of soft parts).

ATF1 CREB1

1.77e-05385219561568
Pubmed

Vasoactive intestinal peptide upregulates MUC2 intestinal mucin via CREB/ATF1.

ATF1 CREB1

1.77e-05385216227528
Pubmed

Tumors with EWSR1-CREB1 and EWSR1-ATF1 fusions: the current status.

ATF1 CREB1

1.77e-05385222510762
Pubmed

Role of tissue-specific transcription factor LFB3 in a cyclic AMP-responsive enhancer of the urokinase-type plasminogen activator gene in LLC-PK1 cells.

ATF1 CREB1

1.77e-0538529671480
Pubmed

The pleiotropy associated with de novo variants in CHD4, CNOT3, and SETD5 extends to moyamoya angiopathy.

SETD5 CHD4

1.77e-05385231474762
Pubmed

CRL2ZER1/ZYG11B recognizes small N-terminal residues for degradation.

ZNF701 ZYG11B

1.77e-05385236496439
Pubmed

NGS testing for cardiomyopathy: Utility of adding RASopathy-associated genes.

BRAF SOS1

1.77e-05385229696744
Pubmed

Nuclear orphan receptors regulate transcription of the gene for the human luteinizing hormone receptor.

NR2F6 NR2F1

1.77e-05385210644740
Pubmed

cAMP-independent activation of the adenovirus type 12 E2 promoter correlates with the recruitment of CREB-1/ATF-1, E1A(12S), and CBP to the E2-CRE.

ATF1 CREB1

1.77e-05385210722738
Pubmed

Activating transcription factor-1 can mediate Ca(2+)- and cAMP-inducible transcriptional activation.

ATF1 CREB1

1.77e-0538528384217
Pubmed

Chicken ovalbumin upstream promoter-transcription factor (COUP-TF) modulates expression of the Purkinje cell protein-2 gene. A potential role for COUP-TF in repressing premature thyroid hormone action in the developing brain.

NR2F1 NR2F2

1.77e-0538529632703
Pubmed

Transcriptional regulation of the MHC class II trans-activator (CIITA) promoter III: identification of a novel regulatory region in the 5'-untranslated region and an important role for cAMP-responsive element binding protein 1 and activating transcription factor-1 in CIITA-promoter III transcriptional activation in B lymphocytes.

ATF1 CREB1

1.77e-05385212391222
Pubmed

Dehydroepiandrosterone sulfate mediates activation of transcription factors CREB and ATF-1 via a Gα11-coupled receptor in the spermatogenic cell line GC-2.

ATF1 CREB1

1.77e-05385223988737
Pubmed

Transcription factors COUP-TFI and COUP-TFII are required for the production of granule cells in the mouse olfactory bulb.

NR2F1 NR2F2

1.77e-05385225922524
Pubmed

MSK1 is required for CREB phosphorylation in response to mitogens in mouse embryonic stem cells.

ATF1 CREB1

1.77e-05385211018520
Pubmed

BRCA1 physically and functionally interacts with ATF1.

ATF1 CREB1

1.77e-05385210945975
Pubmed

Elevated cyclic AMP levels promote BRAFCA/Pten-/- mouse melanoma growth but pCREB is negatively correlated with human melanoma progression.

BRAF CREB1

1.77e-05385229179997
Pubmed

Chicken ovalbumin upstream promoter-transcription factor members repress retinoic acid-induced Cdx1 expression.

NR2F1 NR2F2

1.77e-05385215677473
Pubmed

Regulation of renin expression by the orphan nuclear receptors Nr2f2 and Nr2f6.

NR2F6 NR2F2

1.77e-05385222278040
Pubmed

Friend of GATA 2 physically interacts with chicken ovalbumin upstream promoter-TF2 (COUP-TF2) and COUP-TF3 and represses COUP-TF2-dependent activation of the atrial natriuretic factor promoter.

NR2F6 NR2F2

1.77e-05385211382775
Pubmed

Effects of germline mutations in the Ras/MAPK signaling pathway on adaptive behavior: cardiofaciocutaneous syndrome and Noonan syndrome.

BRAF SOS1

1.77e-05385220186801
Pubmed

Prostaglandin F(2alpha) stimulates MEK-ERK signalling but decreases the expression of alkaline phosphatase in dental pulp cells.

ATF1 CREB1

1.77e-05385220536573
Pubmed

A signature motif mediating selective interactions of BCL11A with the NR2E/F subfamily of orphan nuclear receptors.

NR2F6 NR2F1 NR2F2

2.10e-052285323975195
Pubmed

Heme oxygenase-1 regulates dendritic cell function through modulation of p38 MAPK-CREB/ATF1 signaling.

ATF1 CREB1

3.53e-05485224719331
Pubmed

The cAMP-regulated enhancer-binding protein ATF-1 activates transcription in response to cAMP-dependent protein kinase A.

ATF1 CREB1

3.53e-0548521655749
Pubmed

Induction of Grp78/BiP by translational block: activation of the Grp78 promoter by ATF4 through and upstream ATF/CRE site independent of the endoplasmic reticulum stress elements.

ATF1 CREB1

3.53e-05485212871976
Pubmed

Regulation of vascular endothelial growth factor D by orphan receptors hepatocyte nuclear factor-4 alpha and chicken ovalbumin upstream promoter transcription factors 1 and 2.

NR2F1 NR2F2

3.53e-05485218199540
Pubmed

Secalonic acid D alters the expression and phosphorylation of the transcription factors and their binding to cAMP response element in developing murine secondary palate.

ATF1 CREB1

3.53e-05485211354513
Pubmed

The language phenotype of children and adolescents with Noonan syndrome.

BRAF SOS1

3.53e-05485220543023
Pubmed

MSK1 and MSK2 are required for the mitogen- and stress-induced phosphorylation of CREB and ATF1 in fibroblasts.

ATF1 CREB1

3.53e-05485211909979
Pubmed

Nuclear factor-erythroid 2 (NF-E2) p45-related factor-2 (Nrf2) modulates dendritic cell immune function through regulation of p38 MAPK-cAMP-responsive element binding protein/activating transcription factor 1 signaling.

ATF1 CREB1

3.53e-05485223775080
Pubmed

The COUP-TF nuclear receptors regulate cell migration in the mammalian basal forebrain.

NR2F1 NR2F2

3.53e-05485215548577
Pubmed

CREB proteins function as positive regulators of the translocated bcl-2 allele in t(14;18) lymphomas.

ATF1 CREB1

3.53e-0548528798441
Pubmed

EWSR1 Fusions With CREB Family Transcription Factors Define a Novel Myxoid Mesenchymal Tumor With Predilection for Intracranial Location.

ATF1 CREB1

3.53e-05485228009602
Pubmed

Isolation of a novel family of C(2)H(2) zinc finger proteins implicated in transcriptional repression mediated by chicken ovalbumin upstream promoter transcription factor (COUP-TF) orphan nuclear receptors.

NR2F1 NR2F2

3.53e-05485210744719
Pubmed

Complementary quantitative proteomics reveals that transcription factor AP-4 mediates E-box-dependent complex formation for transcriptional repression of HDM2.

NR2F6 NFIA NR2F1 NR2F2

3.92e-057785419505873
Pubmed

A role for Sp and nuclear receptor transcription factors in a cardiac hypertrophic growth program.

NR2F1 NR2F2

5.87e-0558529177236
Pubmed

Calmodulin-dependent protein kinase II potentiates transcriptional activation through activating transcription factor 1 but not cAMP response element-binding protein.

ATF1 CREB1

5.87e-0558528663317
Pubmed

Molecular basis for recognition of Gly/N-degrons by CRL2ZYG11B and CRL2ZER1.

ZNF701 ZYG11B

5.87e-05585234214466
Pubmed

Disruption of CREB function in brain leads to neurodegeneration.

ATF1 CREB1

5.87e-05585211967539
Pubmed

Heterodimeric interactions between chicken ovalbumin upstream promoter-transcription factor family members ARP1 and ear2.

NR2F6 NR2F2

5.87e-05585210318855
Pubmed

IVIG immunotherapy protects against synaptic dysfunction in Alzheimer's disease through complement anaphylatoxin C5a-mediated AMPA-CREB-C/EBP signaling pathway.

GRIA1 CREB1

8.80e-05685223911420
Pubmed

Six post-implantation lethal knockouts of genes for lipophilic MAPK pathway proteins are expressed in preimplantation mouse embryos and trophoblast stem cells.

BRAF SOS1

8.80e-05685215736129
Pubmed

Identification of synaptotagmin effectors via acute inhibition of secretion from cracked PC12 cells.

SYT9 SYT10

8.80e-05685212860971
Pubmed

Mitogen regulated induction of FRA-1 proto-oncogene is controlled by the transcription factors binding to both serum and TPA response elements.

ATF1 CREB1

8.80e-05685215806162
Pubmed

Spatial control of astrogenesis progression by cortical arealization genes.

NFIA NR2F1

8.80e-05685235818636
Pubmed

Adenosine derived from ecto-nucleotidases in calcific aortic valve disease promotes mineralization through A2a adenosine receptor.

ATF1 CREB1

1.23e-04785225644539
Pubmed

PGE(2) induces macrophage IL-10 production and a regulatory-like phenotype via a protein kinase A-SIK-CRTC3 pathway.

ATF1 CREB1

1.23e-04785223241891
Pubmed

CoupTFI interacts with retinoic acid signaling during cortical development.

NR2F1 NR2F2

1.23e-04785223472160
Pubmed

The orphan nuclear receptors COUP-TFI and COUP-TFII regulate expression of the gonadotropin LHβ gene.

NR2F1 NR2F2

1.23e-04785220797425
Pubmed

Haploinsufficiency of the murine polycomb gene Suz12 results in diverse malformations of the brain and neural tube.

CREB1 NR2F1

1.23e-04785219535498
Pubmed

Germline BRAF mutations in Noonan, LEOPARD, and cardiofaciocutaneous syndromes: molecular diversity and associated phenotypic spectrum.

BRAF SOS1

1.23e-04785219206169
Pubmed

Investigation of gene dosage imbalances in patients with Noonan syndrome using multiplex ligation-dependent probe amplification analysis.

BRAF SOS1

1.23e-04785220302979
Pubmed

Cognitive profile of disorders associated with dysregulation of the RAS/MAPK signaling cascade.

BRAF SOS1

1.23e-04785219133693
Pubmed

The role of human MBF1 as a transcriptional coactivator.

ATF1 CREB1

1.64e-04885210567391
Pubmed

Germline gain-of-function mutations in SOS1 cause Noonan syndrome.

BRAF SOS1

1.64e-04885217143285
Pubmed

Specific ablation of the transcription factor CREB in sympathetic neurons surprisingly protects against developmentally regulated apoptosis.

ATF1 CREB1

1.64e-04885217376811
Pubmed

Modulation of CREB activity by the Rho GTPase regulates cell and organism size during mouse embryonic development.

ATF1 CREB1

1.64e-04885212015964
Pubmed

Discovery of genes required for body axis and limb formation by global identification of retinoic acid-regulated epigenetic marks.

NR2F1 NR2F2

1.64e-04885232421711
Pubmed

Conserved N-terminal cysteine motif is essential for homo- and heterodimer formation of synaptotagmins III, V, VI, and X.

SYT9 SYT10

2.10e-04985210531343
Pubmed

Protein kinase A signalling via CREB controls myogenesis induced by Wnt proteins.

ATF1 CREB1

2.10e-04985215568017
Pubmed

Apoptosis, axonal growth defects, and degeneration of peripheral neurons in mice lacking CREB.

ATF1 CREB1

2.10e-04985211988169
Pubmed

Isolation, characterization, and chromosomal localization of mouse and human COUP-TF I and II genes.

NR2F1 NR2F2

2.10e-0498528530078
Pubmed

Zic4-Lineage Cells Increase Their Contribution to Visual Thalamic Nuclei during Murine Embryogenesis If They Are Homozygous or Heterozygous for Loss of Pax6 Function.

NR2F1 NR2F2

2.10e-04985230406191
Pubmed

The functional interactome of PYHIN immune regulators reveals IFIX is a sensor of viral DNA.

GTPBP4 HAT1 PUM3 CHD4 RBM28 NR2F2

2.20e-0434985625665578
Pubmed

The presence and activation of two essential transcription factors (cAMP response element-binding protein and cAMP-dependent transcription factor ATF1) in the two-cell mouse embryo.

ATF1 CREB1

2.62e-041085219776387
Pubmed

COUP-TFs regulate eye development by controlling factors essential for optic vesicle morphogenesis.

NR2F1 NR2F2

3.20e-041185220147377
Pubmed

Ephrin-A5 and EphA5 interaction induces synaptogenesis during early hippocampal development.

GRIA1 CREB1

3.20e-041185220824214
Pubmed

Interaction of Sox2 with RNA binding proteins in mouse embryonic stem cells.

ATF1 CHD4 POU5F1B CREB1

3.45e-0413585431077711
Pubmed

A census of human transcription factors: function, expression and evolution.

THAP2 NR2F6 NFIA ATF1 POU5F1B ZNF230 CREB1 NR2F1 NR2F2

3.79e-0490885919274049
Pubmed

Transcriptional regulation by the repressor of estrogen receptor activity via recruitment of histone deacetylases.

NR2F1 NR2F2

3.83e-041285215140878
Pubmed

The spatial patterning of mouse cone opsin expression is regulated by bone morphogenetic protein signaling through downstream effector COUP-TF nuclear receptors.

NR2F1 NR2F2

3.83e-041285219812316
CytobandEnsembl 112 genes in cytogenetic band chr7q11

SPDYE11 SPDYE17 SPDYE10 SPDYE13 SPDYE15 SPDYE7P SPDYE8 SPDYE21 SPDYE9 SPDYE5 SPDYE18 SPDYE12 SPDYE14 SPDYE16

1.64e-162718714chr7q11
Cytoband7q11.23

SPDYE10 SPDYE7P SPDYE8 SPDYE9 SPDYE5 SPDYE18 SPDYE14

7.68e-10978777q11.23
Cytoband7q22.1

SPDYE3 SPDYE2 SPDYE2B SPDYE6

6.62e-051138747q22.1
CytobandEnsembl 112 genes in cytogenetic band chr7q22

SPDYE3 SPDYE2 SPDYE2B SPDYE6

8.23e-04219874chr7q22
Cytoband4q32.1

FNIP2 RAPGEF2

1.12e-03268724q32.1
GeneFamilySpeedy/RINGO cell cycle regulator family

SPDYE1 SPDYE7P SPDYE3 SPDYE2 SPDYE8 SPDYE9 SPDYE5 SPDYE2B SPDYE4 SPDYE6

2.61e-25124610756
GeneFamilyNuclear hormone receptors

NR2F6 NR2F1 NR2F2

2.62e-044946371
GeneFamilySynaptotagmins

SYT9 SYT10

8.41e-0417462765
CoexpressionGSE30083_SP2_VS_SP3_THYMOCYTE_UP

GTPBP4 DUSP5 TRPM1 RBM28 ST7L NR2F2 RASAL1

2.60e-06199807M5031
CoexpressionBRUINS_UVC_RESPONSE_LATE

SPDYE1 CCNDBP1 SPDYE7P SPDYE3 SPDYE2 VPS26C HAT1 SPDYE5 SPDYE2B SPDYE4 PCGF5 DKK2 SPDYE6 SPDYE16 SOS1

2.95e-0611988015MM1062
CoexpressionGSE37416_0H_VS_3H_F_TULARENSIS_LVS_NEUTROPHIL_DN

BRAF SETD5 DUSP5 CHD4 RAPGEF2 TAF13

3.16e-05197806M5342
ToppCelldroplet-Kidney-nan-18m-Epithelial-Pecam____kidney_capillary_endothelial_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PIEZO2 WT1-AS STON1 NR2F1 DKK2 ADD2

6.60e-0716981687116c33c5ca8cb1862e103e5607b1df4d264569
ToppCell5'-Parenchyma_lung-Endothelial-Lymphatic_EC-endothelial_cell_of_lymphatic_vessel-Lymphatic_EC_differentiating-Lymphatic_EC_differentiating_L.2.5.1.1|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

DOCK5 PIEZO2 GRIA1 MGAT4C NR2F1 NR2F2

1.05e-061838164d16bfbadf2cd13008c35e23dd2b5b4ecf92ee11
ToppCellCOVID-19-lung-Lymphatic_EC|COVID-19 / Disease (COVID-19 only), tissue and cell type

DOCK5 THBD PIEZO2 MGAT4C NR2F1 NR2F2

1.39e-06192816cbe57cda44232b183821ac633b60a2668265e616
ToppCell3'-Parenchyma_lung-Endothelial-Lymphatic_EC-endothelial_cell_of_lymphatic_vessel|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

DOCK5 THBD PIEZO2 MGAT4C NR2F1 NR2F2

1.43e-06193816040f6bb42aa41d0921371fdda1cc0912c4fe1930
ToppCell3'-Parenchyma_lung-Endothelial-Lymphatic_EC|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

DOCK5 THBD PIEZO2 MGAT4C NR2F1 NR2F2

1.43e-06193816e468287c8b30c56d1de65e8347ade233ba6cf584
ToppCellPCW_13-14-Mesenchymal-Mesenchymal_fibroblastic-mes_immature5_(6)|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung

DOCK5 PIEZO2 NFIA PCCA NR2F1 NR2F2

1.48e-06194816b1bb0f846d2865efdd9bc8842b16b9d069785882
ToppCellPCW_10-12-Mesenchymal-Mesenchymal_fibroblastic-mes_immature5_(6)|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung

DOCK5 PIEZO2 NFIA PCCA NR2F1 NR2F2

1.52e-061958160e55fa5b3cbeb7baee3d4ac272a3bf80381ec937
ToppCellParenchymal-10x3prime_v2-Endothelial-Endothelia_lymphatic|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations

DOCK5 THBD PIEZO2 MGAT4C NR2F1 NR2F2

1.76e-0620081676e90231aa94afc12e618da8ae314c51644acab4
ToppCellParenchymal-10x3prime_v2-Endothelial-Endothelia_lymphatic-Endothelia_Lymphatic|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations

DOCK5 THBD PIEZO2 MGAT4C NR2F1 NR2F2

1.76e-06200816e3e80cb16e0d2e24efc16b62316a6da91bf81ea5
ToppCelldroplet-Kidney-nan-3m-Epithelial-Pecam____kidney_capillary_endothelial_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PIEZO2 WT1-AS STON1 NR2F1 DKK2

1.56e-05172815073a503dc922e3e3ac3528e249b0f8b74402110b
ToppCellAdult-Epithelial-lung_neuroendocrine_cell_(PNEC)|Adult / Lineage, Cell type, age group and donor

PIEZO2 GRIA1 MGAT4C SYT10 SPDYE6

1.70e-051758154db1a3c284488b3f6de7568363f176d74e2a4587
ToppCellAdult-Epithelial-lung_neuroendocrine_cell_(PNEC)-D231|Adult / Lineage, Cell type, age group and donor

PIEZO2 GRIA1 MGAT4C SYT10 SPDYE6

1.70e-051758158d9f44a2633b71fb4d2b4a7d9530f954e07c4a18
ToppCellCOVID-19-Heart-Lymph_EC|COVID-19 / Disease (COVID-19 only), tissue and cell type

DOCK5 THBD PIEZO2 NR2F1 NR2F2

1.79e-05177815326fde0734ef0d7272693966d346ca479b9d8147
ToppCell5'-Adult-LargeIntestine-Endothelial-lymphatic_endothelial-LEC1_(ACKR4+)|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

THBD PIEZO2 GRIA1 NR2F1 NR2F2

1.79e-05177815b1775e05c28883a15c56628028770bc59d3233fb
ToppCell3'-Parenchyma_lung-Endothelial-Lymphatic_EC-endothelial_cell_of_lymphatic_vessel-Lymphatic_EC_differentiating-Lymphatic_EC_differentiating_L.2.5.1.1|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

DOCK5 PIEZO2 MGAT4C NR2F1 NR2F2

1.84e-05178815ad3de3e03a401dac64431a541899445262246347
ToppCellCOVID-19-Heart-Lymph_EC|Heart / Disease (COVID-19 only), tissue and cell type

DOCK5 THBD PIEZO2 NR2F1 NR2F2

1.89e-05179815411620201a860716a8773b92f50f7b94ef34a586
ToppCell3'-Parenchyma_lung-Endothelial-Lymphatic_EC-endothelial_cell_of_lymphatic_vessel-Lymphatic_EC_differentiating-Lymphatic_EC_differentiating_L.2.5.1.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

DOCK5 PIEZO2 MGAT4C NR2F1 NR2F2

1.99e-05181815e898ecb8d8f2eb2204225b7b0d665cadcd241139
ToppCell5'-Parenchyma_lung-Endothelial-Lymphatic_EC-endothelial_cell_of_lymphatic_vessel-Lymphatic_EC_mature-Lymphatic_EC_mature_L.2.5.3.0|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

THBD MGAT4C NR2F1 NR2F2 ADD2

2.16e-05184815e5756afa3181186f9b65552b8df5359ef4024bee
ToppCell5'-Parenchyma_lung-Endothelial-Lymphatic_EC-endothelial_cell_of_lymphatic_vessel-Lymphatic_EC_differentiating|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

DOCK5 PIEZO2 MGAT4C NR2F1 NR2F2

2.27e-0518681540070d9cd20188ba49b32acfca9bc16256b38bf5
ToppCell3'-Parenchyma_lung-Endothelial-Lymphatic_EC-endothelial_cell_of_lymphatic_vessel-Lymphatic_EC_differentiating|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

DOCK5 PIEZO2 MGAT4C NR2F1 NR2F2

2.27e-0518681520340a5b5cc7f07386498a4ef937d6fbc9e347c4
ToppCellCOVID-19-lung-Lymphatic_EC|lung / Disease (COVID-19 only), tissue and cell type

DOCK5 PIEZO2 MGAT4C NR2F1 NR2F2

2.45e-05189815c8db9aaf54ea3cc96c4a2f777c3389e0f31f67f3
ToppCell3'-Parenchyma_lung-Endothelial-Lymphatic_EC-endothelial_cell_of_lymphatic_vessel-Lymphatic_EC_mature|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

THBD PIEZO2 MGAT4C NR2F1 NR2F2

2.65e-05192815291df12b4b5ff11fbaa43033692b8f4b5cdf65a1
ToppCell3'-Parenchyma_lung-Endothelial-Lymphatic_EC-endothelial_cell_of_lymphatic_vessel-Lymphatic_EC_mature-Lymphatic_EC_mature_L.2.5.0.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

THBD PIEZO2 MGAT4C NR2F1 NR2F2

2.65e-0519281535ffe7aa9ffab85eac3326651e901c39d0119650
ToppCellPCW_05-06-Mesenchymal-Mesenchymal_fibroblastic|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung

PIEZO2 NFIA GRIA1 MGAT4C NR2F1

2.78e-0519481585e00861c5068a27d0cf0ae677f420c8245baa9a
ToppCell5'-Parenchyma_lung-Endothelial-Lymphatic_EC|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

THBD PIEZO2 MGAT4C NR2F1 NR2F2

2.85e-051958158f3b455553215f6e191842a5953a79c606f22c08
ToppCellCOPD-Endothelial-Lymphatic|Endothelial / Disease state, Lineage and Cell class

DOCK5 PIEZO2 MGAT4C NR2F1 NR2F2

2.85e-05195815e91ce548ae7224661ee5d2f2639794a5f69798ee
ToppCellIPF-Endothelial-Lymphatic|Endothelial / Disease state, Lineage and Cell class

DOCK5 PIEZO2 MGAT4C NR2F1 NR2F2

2.85e-05195815de88e9d22044b4b3e29676ad02b3e9299cc920ad
ToppCell343B-Endothelial_cells-Endothelial-F_(Lymphatics)-|Endothelial_cells / Donor, Lineage, Cell class and subclass (all cells)

DOCK5 PIEZO2 MGAT4C NR2F1 NR2F2

2.85e-05195815fc75f04eb475c8139cc5c35e6be22e73fb2be9e6
ToppCell5'-Parenchyma_lung-Endothelial-Lymphatic_EC-endothelial_cell_of_lymphatic_vessel|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

THBD PIEZO2 MGAT4C NR2F1 NR2F2

2.85e-051958157e71b1707b34ce47fffadf6f64d9554768221fc6
ToppCell343B-Endothelial_cells-Endothelial-F_(Lymphatics)|Endothelial_cells / Donor, Lineage, Cell class and subclass (all cells)

DOCK5 PIEZO2 MGAT4C NR2F1 NR2F2

2.85e-0519581583d45ff5e5bc704448431149fffb2e4c1278f279
ToppCellfacs-Thymus-Thymus_Epithelium|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

THBD PIEZO2 NFIA NR2F1 NR2F2

2.92e-051968156bc1187dfc4860a4e09032d7ea87ba3d9fe9f363
ToppCellControl-Endothelial-Lymphatic|Endothelial / Disease state, Lineage and Cell class

DOCK5 PIEZO2 MGAT4C NR2F1 NR2F2

2.92e-05196815e0cf617b0f5d9c3c19574f587a3d0ccbf93d8ca4
ToppCellfacs-Thymus-Thymus_Epithelium-18m|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

THBD PIEZO2 NFIA NR2F1 NR2F2

2.92e-05196815c8c89e469402e11aa2a9561e859b6fd1fb66c39b
ToppCell356C-Endothelial_cells-Endothelial-F_(Lymphatics)-|Endothelial_cells / Donor, Lineage, Cell class and subclass (all cells)

DOCK5 PIEZO2 MGAT4C NR2F1 NR2F2

2.92e-05196815b04ca69b0ed44e09c989b575f747e1e819cd8008
ToppCell356C-Endothelial_cells-Endothelial-F_(Lymphatics)|Endothelial_cells / Donor, Lineage, Cell class and subclass (all cells)

DOCK5 PIEZO2 MGAT4C NR2F1 NR2F2

2.92e-05196815a31e227de2dc077b81881295b012d22fedbd65ed
ToppCellnormal_Lung-Endothelial_cells-Lymphatic_ECs|Endothelial_cells / Location, Cell class and cell subclass

DOCK5 PIEZO2 MGAT4C NR2F1 NR2F2

2.99e-05197815c838d0f64e3b43a616a9e381b8139bfe9aa32da7
ToppCellParenchymal-NucSeq-Endothelial-Endothelia_lymphatic|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

THBD PIEZO2 MGAT4C NR2F1 NR2F2

3.07e-051988159ab0db78394e730f6866b2db80047149024ad5f6
ToppCelldistal-1-Endothelial-Lymphatic|1 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

PIEZO2 GRIA1 MGAT4C NR2F1 NR2F2

3.07e-05198815b6fea363463c8dd7e6780c085ece4900266a6286
ToppCellLAM-Endothelial-LymEndo|Endothelial / Condition, Lineage and Cell class

DOCK5 THBD MGAT4C NR2F1 NR2F2

3.07e-05198815ba64b1c95dfaa995045239d412e725596f6c482e
ToppCellParenchymal-NucSeq-Endothelial-Endothelia_lymphatic-Endothelia_Lymphatic|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

THBD PIEZO2 MGAT4C NR2F1 NR2F2

3.07e-05198815e47d0e2c6353315c85d7007742bb16b0f05795ed
ToppCell10x5'-Lung-Lymphocytic_T_CD4-Tfh|Lung / Manually curated celltypes from each tissue

TSPYL2 NR2F1 RASAL1 SPDYE6

1.05e-04134814da3cb572d0c19932619e51e272c0555e91b482ac
ToppCellprimary_visual_cortex-Neuronal-glutamatergic_neuron-L6_CT-L6_CT_VISp_Krt80_Sla|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

NFIA MGAT4C SYT10 RASAL1

1.66e-04151814f50c5ae9dae507df750df25e151b58685fec70ce
ToppCellfacs-Brain_Myeloid-Cortex_-18m-Myeloid-macrophage|Brain_Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DOCK5 NR2F6 THBD DUSP5

1.88e-041568142ba838bc864c2c1767bcab7bb4d790af96b91387
ToppCellCD8+_Memory_T_cell-RSV-6|CD8+_Memory_T_cell / cell class, Virus stimulation and cluster

NR2F6 SPDYE3 BRME1 RAB13

1.97e-041588145ae737757a49fc96bde1e57e02066f9f65654ea1
ToppCellCOVID-19-kidney-Technical/muscle_(Imm)|kidney / Disease (COVID-19 only), tissue and cell type

PIEZO2 CTNNA3 SNTG1 MGAT4C

2.22e-0416381419c28ce16a588a7f4a035c32726f6ccd67702b5b
ToppCellCOVID-19-kidney-Lymphatic_EC|kidney / Disease (COVID-19 only), tissue and cell type

DOCK5 THBD PIEZO2 NR2F1

2.44e-0416781497d0fea1f41c1c00e36d9b5c4c1f0dd85087056f
ToppCell3'-Pediatric_IBD-SmallIntestine-Endothelial-lymphatic_endothelial-LEC1_(ACKR4+)|Pediatric_IBD / Celltypes from developing, pediatric, Crohn's, & adult GI tract

THBD PIEZO2 NR2F1 NR2F2

2.61e-041708144848965bc7e9356c6601bb41eeea1553d2eea87e
ToppCelldroplet-Marrow-BM-1m-Lymphocytic-NK_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DOCK5 NR2F6 THBD RAPGEF2

2.91e-04175814c1c722db42da9b8a2a46e516ddb83d9be5e2e504
ToppCelldroplet-Heart-HEART_(LV+RV_ONLY)-30m-Endothelial-leukocyte|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PIEZO2 C3orf62 GRIA1 NR2F2

2.91e-04175814f6e1d7297a4dbb38e1ab4f738d91f0e62abaee69
ToppCellE18.5-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_vascular-VSMC-VSMC_prolif|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

CTNNA3 SCUBE3 HAT1 GRIA1

3.04e-041778144553ee8cd9c24db6511b09fe49ed11a89e7cde9e
ToppCell356C-Fibroblasts-Fibroblast-G-|356C / Donor, Lineage, Cell class and subclass (all cells)

PIEZO2 GRIA1 NR2F1 NR2F2

3.04e-041778147617270f49cd6b7ba66db72d20560cee985012b2
ToppCell356C-Fibroblasts-Fibroblast-G|356C / Donor, Lineage, Cell class and subclass (all cells)

PIEZO2 GRIA1 NR2F1 NR2F2

3.04e-041778148220cc2fc0ee8764a67a3be51d75248be2453040
ToppCell368C-Lymphocytic-NK_cells-NK_cell_C|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)

FNIP2 DOCK5 PROSER1 TAF13

3.11e-0417881450bb1f2c6a8d050ff2af217fd76c3b1b7b4a4a69
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast-kidney_interstitial_fibroblast_5|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

PIEZO2 TSPYL2 NR2F1 NR2F2

3.11e-0417881478a0c6340001a77f5b2d890b6263f574af2e72da
ToppCell3'-Pediatric_IBD-SmallIntestine-Mesenchymal-fibroblastic-Stromal_3_(C7+)|Pediatric_IBD / Celltypes from developing, pediatric, Crohn's, & adult GI tract

NFIA TUB NR2F1 NR2F2

3.17e-04179814dcd0a83f0592ae27f814d064b4791f84c3c86e64
ToppCellBrain_organoid-organoid_Kanton_Nature-Organoid-4M-Neuronal-ventral_progenitors_and_neurons_2|Organoid-4M / Sample Type, Dataset, Time_group, and Cell type.

KCNU1 SNTG1 HAT1 RAB13

3.17e-04179814d95367d689732ab2653e8d70d8d8e5eb15ae6eef
ToppCellILEUM-non-inflamed-(7)_Lymphatics|non-inflamed / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)

DOCK5 PIEZO2 NFIA NR2F1

3.17e-0417981499777a8931356d1206b8ab22aaa1b1d5a600b809
ToppCellASK454-Endothelial-Lymphatic|ASK454 / Donor, Lineage and Cell class of Lung cells from Dropseq

PIEZO2 EML6 NR2F1 NR2F2

3.17e-04179814fd84a79f76a01c0377dff5b20016b004d369f96f
ToppCell5'-Adult-Appendix-Endothelial-lymphatic_endothelial-LEC6_(ADAMTS4+)|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

THBD PIEZO2 GRIA1 NR2F1

3.38e-04182814fd786c88826ad3d5cc5c3d80f8e392d6be1b5267
ToppCell5'-Parenchyma_lung-Endothelial-Lymphatic_EC-endothelial_cell_of_lymphatic_vessel-Lymphatic_EC_differentiating-Lymphatic_EC_differentiating_L.2.5.1.0|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

DOCK5 PIEZO2 MGAT4C NR2F1

3.38e-0418281453c267ee327e116dbd89d5927ed3bdf78d25ee62
ToppCelldroplet-Kidney-nan-21m-Epithelial-Pecam____kidney_capillary_endothelial_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PIEZO2 WT1-AS NR2F1 DKK2

3.45e-04183814f55081068213cc1cdb2acad58ff10f6b48b44c72
ToppCell5'-Adult-Appendix-Endothelial-lymphatic_endothelial|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

THBD PIEZO2 GRIA1 NR2F1

3.52e-04184814453295362888c9a59d0e73c7a5b15914c50ff591
ToppCelldroplet-Kidney-KIDNEY-1m-Epithelial-Pecam____kidney_capillary_endothelial_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PIEZO2 WT1-AS NR2F1 DKK2

3.52e-041848141c857126c0ea0671f0d60b048efca288d348d653
ToppCellCOVID-19-Neuronal_cells|COVID-19 / group, cell type (main and fine annotations)

DOCK5 PIEZO2 MGAT4C NR2F2

3.60e-0418581436ce23893915f5c380cca39b2c33a516edf31c3a
ToppCellEndothelial-B-Donor_07|World / lung cells shred on cell class, cell subclass, sample id

THBD PIEZO2 DUSP5 NR2F1

3.60e-04185814133c9dc64d564dae4aeeeca22f386aa3f13fa980
ToppCellCOVID-19-Neuronal_cells-Neuronal_cells|COVID-19 / group, cell type (main and fine annotations)

DOCK5 PIEZO2 MGAT4C NR2F2

3.60e-041858144a095829992b39856a73bdfac03ee68b9aa0d3b8
ToppCellILEUM-inflamed-(7)_Lymphatics|inflamed / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)

DOCK5 PIEZO2 NFIA NR2F1

3.60e-04185814d711dd2e91cfee723dae1ccb2b910b8cf3becc3b
ToppCell343B-Endothelial_cells-Endothelial-F_(Lymphatics)|343B / Donor, Lineage, Cell class and subclass (all cells)

PIEZO2 MGAT4C NR2F1 NR2F2

3.67e-041868147a8da2ad140bea3207bd868212cc5e201d586772
ToppCell343B-Endothelial_cells-Endothelial-F_(Lymphatics)-|343B / Donor, Lineage, Cell class and subclass (all cells)

PIEZO2 MGAT4C NR2F1 NR2F2

3.67e-04186814dc394034929c6b10ae0e1c1a028cc3d4ce873298
ToppCellAnterior_Cingulate_gyrus_(CgG)|World / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

NFIA GRIA1 PUM3 MGAT4C

3.67e-0418681432af3f211f9ad5d5c6b86b83325cfbf2f8466b56
ToppCellPrimary_Visual_cortex_(V1C)-Non-neuronal-Macroglial-Oligo-Oligodendrocyte-Oligo_L4-6_MOBP_COL18A1|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

DOCK5 PIEZO2 CTNNA3 SYT9

3.67e-04186814d57c40b3fe5cfc87e771df76533d9a3e94678b04
ToppCellAdult-Mesenchymal-matrix_fibroblast_1_cell-D175|Adult / Lineage, Cell type, age group and donor

PIEZO2 GRIA1 NR2F1 NR2F2

3.75e-04187814e15d2967aac248da3517bc2c7d1beaa1d5a0aa7f
ToppCellkidney_cells-Hypertensive_with+without-CKD-Endothelial-lymphatic_endothelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

DOCK5 THBD PIEZO2 NR2F1

3.75e-0418781465d406122dffe18279f14a1ed35ba091730b97be
ToppCellkidney_cells-Hypertensive_with+without-CKD-Endothelial-lymphatic_endothelial_cell-lymphatic_endothelial_cell_of_renal_cortex-lymphatic_endothelial_cell_of_renal_cortex|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

DOCK5 THBD PIEZO2 NR2F1

3.75e-041878144c15c0ed41a55271fc793cb76fee97fa64190369
ToppCellkidney_cells-Hypertensive_with+without-CKD-Endothelial-lymphatic_endothelial_cell-lymphatic_endothelial_cell_of_renal_cortex|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

DOCK5 THBD PIEZO2 NR2F1

3.75e-041878145274f2b302bbf7fed30c480af4f35058d2cf61e0
ToppCellAdult-Endothelial-endothelial_cell_of_lymph_vessel-D175|Adult / Lineage, Cell type, age group and donor

PIEZO2 MGAT4C NR2F1 NR2F2

3.75e-041878141e52d3d9d664c813d859b5b75e4c07b218818f95
ToppCell390C-Endothelial_cells-Endothelial-F_(Lymphatics)-|390C / Donor, Lineage, Cell class and subclass (all cells)

THBD MGAT4C NR2F1 NR2F2

3.82e-041888141f40b959777d18ad88d239df8cca304f062ba04c
ToppCellkidney_cells-Renal_AKI_(acute_kidney_injury)-Endothelial-lymphatic_endothelial_cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

DOCK5 THBD PIEZO2 NR2F1

3.82e-0418881426915db8863f4115b46a81982e187322e21600fd
ToppCellkidney_cells-Renal_AKI_(acute_kidney_injury)-Endothelial-lymphatic_endothelial_cell-lymphatic_endothelial_cell_of_renal_cortex|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

DOCK5 THBD PIEZO2 NR2F1

3.82e-041888143f76c0f912f8f023ea425be7f43593b3d7f967e3
ToppCellASK428-Endothelial-Lymphatic|ASK428 / Donor, Lineage and Cell class of Lung cells from Dropseq

THBD PIEZO2 NR2F1 NR2F2

3.82e-04188814c371bc340966cfe9205cbf4b62c6452f49f2559f
ToppCellkidney_cells-Renal_AKI_(acute_kidney_injury)-Endothelial-lymphatic_endothelial_cell-lymphatic_endothelial_cell_of_renal_cortex-lymphatic_endothelial_cell_of_renal_cortex|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

DOCK5 THBD PIEZO2 NR2F1

3.82e-0418881461ee7b152745164293d8a44ef91ee2393efbdca5
ToppCellChildren_(3_yrs)-Endothelial-endothelial_cell_of_lymph_vessel-D046|Children_(3_yrs) / Lineage, Cell type, age group and donor

DOCK5 PIEZO2 NR2F1 NR2F2

3.82e-041888142db80767903703e7e0a1a37c598f7877a909ee94
ToppCellChildren_(3_yrs)-Endothelial-endothelial_cell_of_lymph_vessel|Children_(3_yrs) / Lineage, Cell type, age group and donor

DOCK5 PIEZO2 NR2F1 NR2F2

3.82e-04188814c2805232618a7b6f844d34e37ad458a9923dbfe1
ToppCell390C-Endothelial_cells-Endothelial-F_(Lymphatics)|390C / Donor, Lineage, Cell class and subclass (all cells)

THBD MGAT4C NR2F1 NR2F2

3.82e-04188814aa69e3f44d506f5ef358a3374ac5160d847c858f
ToppCellE17.5-Mesenchymal-developing_mesenchymal_cell-mesenchymal_myogenic_precursor_(Axin2+)|E17.5 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

DUSP5 RAPGEF2 NR2F1 NR2F2

3.90e-0418981426cfe5b7e7f477f225f4e9f25f983f432f01e183
ToppCellFetal_brain-organoid_Tanaka_cellReport-GW09-Neuronal-Neuron|GW09 / Sample Type, Dataset, Time_group, and Cell type.

NFIA ASNS GOLPH3 NR2F1

3.90e-041898143717d1148e26ac78a26aea0ca1dbfbb9d3668877
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Endothelial-lymphatic_endothelial_cell-lymphatic_endothelial_cell_of_renal_cortex|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

DOCK5 THBD PIEZO2 GRIA1

3.98e-04190814876bd2eb9ed2624cb23bdcf6b989e4fa34d099e3
ToppCellAdult-Endothelial-endothelial_cell_of_lymph_vessel|Adult / Lineage, Cell type, age group and donor

PIEZO2 MGAT4C NR2F1 NR2F2

3.98e-0419081491bf3b7e9148589757436a53a4f58e0ebfe54400
ToppCellTransplant_Alveoli_and_parenchyma-Endothelial-Lymphatic|Transplant_Alveoli_and_parenchyma / Tissue, Lineage and Cell class of Lung Cells from 10X

PIEZO2 MGAT4C NR2F1 NR2F2

3.98e-041908148d6ec2fc0af19a5cb16fff34f8b131b71b33d45f
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Endothelial-lymphatic_endothelial_cell-lymphatic_endothelial_cell_of_renal_cortex-lymphatic_endothelial_cell_of_renal_cortex|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

DOCK5 THBD PIEZO2 GRIA1

3.98e-04190814be9f36127028f52ca5fc1b32ba15a6c26aad69ac
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Endothelial-lymphatic_endothelial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

DOCK5 THBD PIEZO2 GRIA1

3.98e-0419081409a8855901c3c9332dbaab3e40166485b696d0f1
ToppCellBrain_organoid-organoid_Paulsen_bioRxiv-3.5_mon-Neuronal-Immature_INs|3.5_mon / Sample Type, Dataset, Time_group, and Cell type.

DOCK5 SNTG1 SYT10 NR2F2

3.98e-04190814842760bfe0a52e67bad800efa7d99448a4a23ebb
ToppCell3'-Pediatric_IBD-SmallIntestine-Endothelial-lymphatic_endothelial-LEC3_(ADGRG3+)|Pediatric_IBD / Celltypes from developing, pediatric, Crohn's, & adult GI tract

DOCK5 PIEZO2 NR2F1 NR2F2

4.06e-04191814361b123c8289015206d5e706ab2c615d9a724179
ToppCell3'-Pediatric_IBD-SmallIntestine-Endothelial-lymphatic_endothelial|Pediatric_IBD / Celltypes from developing, pediatric, Crohn's, & adult GI tract

DOCK5 PIEZO2 NR2F1 NR2F2

4.06e-04191814011dc22c488369734749e839d65d52fe46b6a1a4
ToppCellP07-Mesenchymal-developing_mesenchymal_cell-mesenchymal_myogenic_precursor_(Axin2+)|P07 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

DUSP5 RAPGEF2 NR2F1 NR2F2

4.06e-041918142ad717b59215ad8d933e9637d363b65d7298e5d4
ToppCell367C-Endothelial_cells-Endothelial-F_(Lymphatics)-|Endothelial_cells / Donor, Lineage, Cell class and subclass (all cells)

DOCK5 PIEZO2 MGAT4C NR2F1

4.14e-041928145f4f44f15d3a2846981e68296643a4634930a211
ToppCellIPF-Endothelial-Lymphatic|IPF / Disease state, Lineage and Cell class

PIEZO2 MGAT4C NR2F1 NR2F2

4.14e-041928142496edd8f3a41146d418879de9ee2ccc7857431f
ToppCell367C-Endothelial_cells-Endothelial-F_(Lymphatics)|Endothelial_cells / Donor, Lineage, Cell class and subclass (all cells)

DOCK5 PIEZO2 MGAT4C NR2F1

4.14e-041928145e709c0714e8eba27e03a6def0544256bedb3ced
ToppCellPND10-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_vascular-VSMC-VSMC_mature|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

NFIA CTNNA3 SCUBE3 GRIA1

4.14e-0419281426d9207e72bbef5e0046de511e2c9ff752b726f3
ToppCellCOPD-Endothelial-Lymphatic|World / Disease state, Lineage and Cell class

PIEZO2 MGAT4C NR2F1 NR2F2

4.22e-0419381425bdc557055b5bce6a21f8696b48e991c696b979
DrugFluspirilen [1841-19-6]; Down 200; 8.4uM; HL60; HT_HG-U133A

DOCK5 GTPBP4 NR2F6 ZNF701 ST7L TAF13 NR2F2

4.55e-061967773086_DN
DiseaseArts syndrome (implicated_via_orthology)

PRPSAP1 PRPSAP2

5.87e-062722DOID:0050647 (implicated_via_orthology)
DiseaseX-linked nonsyndromic deafness (implicated_via_orthology)

PRPSAP1 PRPSAP2

5.87e-062722DOID:0050566 (implicated_via_orthology)
DiseaseCharcot-Marie-Tooth disease X-linked recessive 5 (implicated_via_orthology)

PRPSAP1 PRPSAP2

1.76e-053722DOID:0110210 (implicated_via_orthology)
DiseaseClear Cell Sarcoma of Soft Tissue

ATF1 CREB1

3.51e-054722C0206651
DiseaseMorphine Abuse

GRIA1 CREB1

1.22e-047722C0600272
DiseaseMorphine Dependence

GRIA1 CREB1

1.22e-047722C0026552
DiseaseNoonan syndrome

BRAF SOS1

2.09e-049722cv:C0028326
DiseaseTurner Syndrome, Male

BRAF SOS1

3.18e-0411722C0041409
DiseaseFemale Pseudo-Turner Syndrome

BRAF SOS1

3.18e-0411722C1527404
DiseaseNoonan Syndrome 1

BRAF SOS1

3.18e-0411722C4551602
Diseaseankle injury

PRPSAP2 GRIA1 MGAT4C

4.11e-0459723EFO_1002021
DiseaseRASopathy

BRAF SOS1

6.04e-0415722cv:C5555857
Diseaseresponse to ketamine

MAEA SYT10 ADD2

6.50e-0469723EFO_0009748
Diseaseestrogen-receptor negative breast cancer

KCNU1 POU5F1B SPDYE12

7.07e-0471723EFO_1000650
DiseaseNoonan-Like Syndrome With Loose Anagen Hair

BRAF SOS1

9.77e-0419722C3501846
DiseaseCostello syndrome (disorder)

BRAF SOS1

9.77e-0419722C0587248
DiseaseNoonan syndrome-like disorder with loose anagen hair

BRAF SOS1

9.77e-0419722C1843181
DiseaseCardio-facio-cutaneous syndrome

BRAF SOS1

9.77e-0419722C1275081
Diseasealpha-tocopherol measurement

VPS26C SOS1

1.08e-0320722EFO_0007898
DiseaseLEOPARD Syndrome

BRAF SOS1

1.31e-0322722C0175704
DiseaseNoonan Syndrome

BRAF SOS1

1.57e-0324722C0028326
Diseasetype 2 diabetes mellitus (implicated_via_orthology)

NR2F6 NR2F1 NR2F2

2.19e-03105723DOID:9352 (implicated_via_orthology)
Diseasefree androgen index

FNIP2 DOCK5 NR2F6 NFIA ATF1

2.22e-03374725EFO_0007005
Diseaseexecutive function measurement

PIEZO2 POLR1C SNTG1 RAPGEF2 NR2F1

2.28e-03376725EFO_0009332
Diseaselung carcinoma, family history of lung cancer

SYT9 TUB

2.28e-0329722EFO_0001071, EFO_0006953

Protein segments in the cluster

PeptideGeneStartEntry
NAVKKRLMTDRRIGC

ASNS

241

P08243
RLMAECLKKKRDERP

BRAF

691

P15056
RAALGRMCTVIKRQK

GTPBP4

131

Q9BZE4
MVCRRKKKRCHRDGM

DKK2

101

Q9UBU2
KGKMRRIDCLRQADK

NFIA

111

Q12857
CKMDLGRTRRISFKG

RASAL1

386

O95294
RLLLGNKCDMEAKRK

RAB13

116

P51153
GVRIKECRVMRDLKG

RBM28

516

Q9NW13
CRLKKCFRVGMRKEA

NR2F6

111

P10588
CRLKKCLKVGMRREA

NR2F1

141

P10589
LKKCLKVGMRREAVQ

NR2F2

136

P24468
RRKDCDKEKRVKLMS

PUM3

146

Q15397
CKAETLMQARKRKRT

POU5F1B

221

Q06416
KMRCLRKRSTVSFLG

MGAT4C

16

Q9UBM8
VVKGLMKKFIRCSTR

PCGF5

156

Q86SE9
KSRLRKMKSCLEFSL

MAEA

186

Q7L5Y9
MAGCTRKLTHLRKRI

KIAA0895

1

Q8NCT3
KKKGLLRLARKGSMR

NIPA2

31

Q8N8Q9
RMKKCLKGISSRISG

KCNU1

636

A8MYU2
DFKEAVRKVMRRKCG

OR11L1

296

Q8NGX0
RGEIACRVIRTCKKM

PCCA

71

P05165
RNKEVKGALRKAMTC

OR6X1

291

Q8NH79
LFRVNMSEKKRCKRI

PROSER1

106

Q86XN7
MCKKTRDLRRQLRKA

CTNNA3

366

Q9UI47
DIKRGKRKRLSSVMC

CCDC82

176

Q8N4S0
KQRDLAKMRKCLRPE

HAT1

366

O14929
MTKRKKLRTSGEGLC

BRME1

1

Q0VDD7
MELKEGKKHTCGLRR

DOCK5

306

Q9H7D0
ALVRASKACLKKIRM

CCNDBP1

246

O95273
RLKSAIEKAMISCRK

FNIP2

346

Q9P278
GEMSEKLRRCRKELT

C3orf62

11

Q6ZUJ4
EACGMRRKSLLTRKV

GOLPH3

106

Q9H4A6
LMKNREAARECRRKK

CREB1

276

P16220
KMRKRGSIVCKLLAS

PRPSAP1

106

Q14558
QCKMRKRGSIVSKLL

PRPSAP2

116

O60256
HRMLAVRKLKKGGRC

EML6

1031

Q6ZMW3
KSRSESKRMKGFCLI

GRIA1

831

P42261
PKSKRQKKERMLLCR

CHD4

66

Q14839
CLRQRMERRLKGSLK

SCUBE3

571

Q8IX30
LRKMLRKEAAARCVV

DUSP5

11

Q16690
LMCDGRRLKKRKTST

SYT9

396

Q86SS6
LCHLRKKQGAARAKM

THBD

536

P07204
MCKILKDSDLLDRRK

SNTG1

341

Q9NSN8
AETLCGLKMKAKRRR

SPDYE10

86

P0DUX0
AETLCGLKMKAKRRR

SPDYE11

86

P0DTA3
AETLCGLKMKAKRRR

SPDYE8

86

P0DUD1
CDKCRGMSRGKVIRL

SETD5

106

Q9C0A6
CNMKKSRLGRSRAVR

WT1-AS

31

Q06250
LVSEAIKVLMGKCRR

POLR1C

321

O15160
GKRKRLFSKELRCMM

TAF13

26

Q15543
GMEKICSKSLAKRRL

SOS1

386

Q07889
LCGLKMKLKRRRVSL

SPDYE2B

176

A6NHP3
LAKGERLMRCKISSV

ADD2

126

P35612
MKNREAARECRRKKK

ATF1

221

P18846
CKIRLHMGDLRKKVA

C11orf42

121

Q8N5U0
ACAAKAKRRLMTLTK

RAPGEF2

376

Q9Y4G8
MRLKRACIRKAKISA

ZYG11B

81

Q9C0D3
KKRKTRGRCEVVIME

TSPYL2

411

Q9H2G4
KSLKAKMNRRACLGS

STON1

591

Q9Y6Q2
AETLCGLKMKAKRRR

SPDYE12

86

P0DUX1
AETLCGLKMKAKRRR

SPDYE13

86

A0A494C0Z2
AETLCGLKMKAKRRR

SPDYE14

86

P0DUD3
AETLCGLKMKAKRRR

SPDYE15

86

P0DUD4
LCGLKMKLKRRRVSL

SPDYE16

136

A6NNV3
AETLCGLKMKAKRRR

SPDYE17

86

P0DUD2
LCGLKMKLKRRRVSL

SPDYE18

176

P0DV79
LCGLKMKLKRRRVLL

SPDYE21

176

A0A494C086
LCGLKMKLKRRRVSL

SPDYE2

176

Q495Y8
LCGLKMKAKRRRVSL

SPDYE3

81

A6NKU9
AETLCGLKMKAKRRR

SPDYE3

151

A6NKU9
TLCGLKMKAKRRRVS

SPDYE3

226

A6NKU9
VAETLCGLKMKAKRR

SPDYE3

296

A6NKU9
CGLKMKAKRRRVSLV

SPDYE3

301

A6NKU9
ETLCGLKMKAKRRRV

SPDYE3

371

A6NKU9
LCGLKMKLKRKRASS

SPDYE4

86

A6NLX3
LCGLKMKLKRRRVSL

SPDYE5

176

A6NIY4
LCGLKMKLKRRRVSL

SPDYE6

176

P0CI01
MLCGLKMKLKRRRVS

SPDYE7P

31

Q495Y7
CGLKMKLKRRRVSLV

SPDYE1

136

Q8NFV5
LRIERCMLTREIKKG

PIEZO2

1681

Q9H5I5
KMKLRECLNIRKSLF

TTC41P

966

Q6P2S7
KRRLAMCARKLGRIR

ST7L

296

Q8TDW4
MCARKLGRIREAVKI

ST7L

301

Q8TDW4
SLMCEGRRLKKRKTT

SYT10

406

Q6XYQ8
IMRLSGRCRKKREGD

TRPM1

1121

Q7Z4N2
MLCDEKAQKRRKRKA

ZNF480

1

Q8WV37
LREKLSKCDMRGKEF

ZNF230

191

Q9UIE0
LCGLKMKLKRRRVSL

nan

136

A6NJR5
AETLCGLKMKAKRRR

SPDYE9

86

A0A494C191
RKNKMSLALKNIRCR

ZNF280C

601

Q8ND82
LEKEIASLRRKMKTC

THAP2

141

Q9H0W7
ASLRRKMKTCLQKER

THAP2

146

Q9H0W7
RKRKRKAKESGMALL

ZNF701

56

Q9NV72
KCRITRDKKGMDRGM

TUB

266

P50607
RCDMKRSLLAKDLTK

VPS26C

121

O14972
RSEKRARKAMSKLGL

NACA2

71

Q9H009