Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
DomainuDENN

DENND4A DENND2B

3.24e-0414362SM00800
DomainuDENN

DENND4A DENND2B

3.73e-0415362PF03456
DomainDENN

DENND4A DENND2B

4.26e-0416362PF02141
DomainUDENN

DENND4A DENND2B

4.26e-0416362PS50946
DomainDDENN

DENND4A DENND2B

4.26e-0416362PS50947
DomaindDENN_dom

DENND4A DENND2B

4.26e-0416362IPR005112
DomainuDENN_dom

DENND4A DENND2B

4.26e-0416362IPR005113
DomaindDENN

DENND4A DENND2B

4.26e-0416362PF03455
DomainDENN

DENND4A DENND2B

4.26e-0416362SM00799
DomainDENN

DENND4A DENND2B

4.26e-0416362PS50211
DomainDENN_dom

DENND4A DENND2B

4.26e-0416362IPR001194
DomaindDENN

DENND4A DENND2B

4.26e-0416362SM00801
DomaintRNA-bd_arm

SOX6 TRAK1

9.71e-0424362IPR010978
DomainTNFR/NGFR_Cys_rich_reg

LAMA5 TNFRSF13B

1.84e-0333362IPR001368
Domain-

NR2E3 GATA1

5.39e-03573623.30.50.10
DomainZnf_NHR/GATA

NR2E3 GATA1

5.58e-0358362IPR013088
DomainRhoGAP

ARHGAP20 ARHGAP12

6.35e-0362362SM00324
DomainRhoGAP

ARHGAP20 ARHGAP12

6.55e-0363362PF00620
DomainRHOGAP

ARHGAP20 ARHGAP12

6.76e-0364362PS50238
DomainRhoGAP_dom

ARHGAP20 ARHGAP12

6.76e-0364362IPR000198
Domain-

ARHGAP20 ARHGAP12

6.76e-03643621.10.555.10
DomainSAM_1

DDHD2 PPFIBP1

7.60e-0368362PF00536
Pubmed

Upregulation of human with-no-lysine kinase-4 gene expression by GATA-1 acetylation.

WNK4 GATA1

1.23e-06239218793746
Pubmed

Interactomes of Glycogen Synthase Kinase-3 Isoforms.

YTHDC2 DENND4A DDHD2 PPFIBP1 TRAK1

3.64e-0620939536779422
Pubmed

Loss of USP28 and SPINT2 expression promotes cancer cell survival after whole genome doubling.

USP28 NUMA1

3.67e-06339234962618
Pubmed

Proteome-scale mapping of binding sites in the unstructured regions of the human proteome.

TMEM132C SYNPO2 BLZF1 WNK4 APC2 NUMA1

7.97e-0643039635044719
Pubmed

Abnormalities in neural crest cell migration in laminin alpha5 mutant mice.

LAMA5 NEUROD1

1.22e-05539216316641
Pubmed

Meta-analysis of three genome-wide association studies identifies susceptibility loci for colorectal cancer at 1q41, 3q26.2, 12q13.13 and 20q13.33.

LAMA5 DIP2B

1.22e-05539220972440
Pubmed

Extracellular matrix of secondary lymphoid organs impacts on B-cell fate and survival.

LAMA5 TNFRSF13B

1.83e-05639223847204
Pubmed

NeuroD1 reprograms chromatin and transcription factor landscapes to induce the neuronal program.

NEUROD1 APC2

1.83e-05639226516211
Pubmed

A High-Density Human Mitochondrial Proximity Interaction Network.

MIEF1 DIP2B YTHDC2 TUT4 DDHD2 HERC2 VPS13B ARHGAP12 TRAK1

3.24e-05149639932877691
Pubmed

Expression of mouse Foxi class genes in early craniofacial development.

FOXI2 NEUROD1

3.42e-05839215376323
Pubmed

A central chaperone-like role for 14-3-3 proteins in human cells.

MIEF1 DIP2B DENND4A DENND2B PPFIBP1 WNK4 TRAK1

4.29e-0586139736931259
Pubmed

An atlas of combinatorial transcriptional regulation in mouse and man.

SOX6 NR2E3 DENND4A NEUROD1 HOXC9 BLZF1 GATA1

4.82e-0587739720211142
Pubmed

Oncogenic transcription factor Evi1 regulates hematopoietic stem cell proliferation through GATA-2 expression.

MECOM GATA1

5.48e-051039215889140
Pubmed

A systematic screen for CDK4/6 substrates links FOXM1 phosphorylation to senescence suppression in cancer cells.

SYNPO2 TRAK1 NUMA1

7.68e-057339322094256
Pubmed

A 5' untranslated region containing the IRES element in the Runx1 gene is required for angiogenesis, hematopoiesis and leukemogenesis in a knock-in mouse model.

MECOM GATA1

1.46e-041639220647008
Pubmed

Dysplastic definitive hematopoiesis in AML1/EVI1 knock-in embryos.

MECOM GATA1

1.46e-041639215914564
Pubmed

Identification of susceptibility loci for colorectal cancer in a genome-wide meta-analysis.

LAMA5 DIP2B

1.65e-041739224737748
Pubmed

The CCND1 c.870G>A polymorphism is a risk factor for t(11;14)(q13;q32) multiple myeloma.

MECOM HERC2

1.65e-041739223502783
Pubmed

Growth disturbance in fetal liver hematopoiesis of Mll-mutant mice.

HOXC9 GATA1

1.85e-04183929639506
Pubmed

Temporal profiling of photoreceptor lineage gene expression during murine retinal development.

NR2E3 NEUROD1

2.07e-041939228288836
Pubmed

Synergistic co-regulation and competition by a SOX9-GLI-FOXA phasic transcriptional network coordinate chondrocyte differentiation transitions.

SOX6 WNK4

2.54e-042139229659575
Pubmed

DCC is specifically required for the survival of retinal ganglion and displaced amacrine cells in the developing mouse retina.

NR2E3 NEUROD1

3.05e-042339220875817
Pubmed

The mouse Foxi3 transcription factor is necessary for the development of posterior placodes.

FOXI2 NEUROD1

3.33e-042439226550799
Pubmed

Notch 1 inhibits photoreceptor production in the developing mammalian retina.

NR2E3 NEUROD1

3.62e-042539216452096
Pubmed

Wnt signals mediate a fate decision between otic placode and epidermis.

FOXI2 NEUROD1

3.62e-042539216452098
Pubmed

Topoisomerase IIβ Selectively Regulates Motor Neuron Identity and Peripheral Connectivity through Hox/Pbx-Dependent Transcriptional Programs.

MECOM HOXC9

3.62e-042539229379870
Pubmed

Requirements for Neurogenin2 during mouse postnatal retinal neurogenesis.

NR2E3 NEUROD1

4.88e-042939230048641
Pubmed

Roles of histone H3K27 trimethylase Ezh2 in retinal proliferation and differentiation.

NR2E3 NEUROD1

4.88e-042939225556712
Pubmed

The steroid receptor RNA activator protein is recruited to promoter regions and acts as a transcriptional repressor.

BLZF1 GATA1

5.58e-043139220398657
Pubmed

The transcription factor RBP-J is essential for retinal cell differentiation and lamination.

NR2E3 NEUROD1

6.72e-043439220017954
Pubmed

Chromatin state signatures associated with tissue-specific gene expression and enhancer activity in the embryonic limb.

MECOM HOXC9

7.54e-043639222421546
Pubmed

Family-wide characterization of the DENN domain Rab GDP-GTP exchange factors.

DENND4A DENND2B

7.96e-043739220937701
Pubmed

Stage-dependent requirement of neuroretinal Pax6 for lens and retina development.

NR2E3 NEUROD1

8.84e-043939224523460
Pubmed

Human transcription factor protein interaction networks.

PCF11 SOX6 MECOM HOXC9 HERC2 NUMA1 GATA1

9.45e-04142939735140242
Pubmed

Estrogen-regulated feedback loop limits the efficacy of estrogen receptor-targeted breast cancer therapy.

TUT4 DDHD2 DENND2B VPS13B ALPK2

9.73e-0468639529987050
InteractionHOXC13 interactions

FOXI2 NR2E3 HOXC9

1.32e-0524393int:HOXC13
GeneFamilyGuanylate cyclase receptors|DENN/MADD domain containing

DENND4A DENND2B

5.85e-0425262504
GeneFamilyRho GTPase activating proteins|BCH domain containing

ARHGAP20 ARHGAP12

2.33e-0350262721
GeneFamilySterile alpha motif domain containing

DDHD2 PPFIBP1

7.06e-0388262760
GeneFamilyBasic helix-loop-helix proteins

NEUROD1 ASCL5

1.08e-02110262420
ToppCellPrimary_Visual_cortex_(V1C)-Neuronal-Inh_GABAergic-i_Gaba_3|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

SOX6 TMEM132C ARHGAP20 PRRT4 ARHGAP12

6.53e-0719039526843ec1d19ac85a50990705353b802745d33e4d
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast-kidney_interstitial_fibroblast_5|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

SYNPO2 ARHGAP20 DENND2B PRRT4

1.39e-05168394d19a115365c5415e51c039718d7669de788fcf33
ToppCellSomatosensory_Cortex_(S1)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_PVALB_1-Inh_L3-4_PVALB_HOMER3|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

SOX6 TMEM132C PRRT4 ARHGAP12

1.83e-051803948f774dcacc1626e4e6492f1eb927b0ed56fbe686
ToppCellPrimary_Visual_cortex_(V1C)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_PVALB_1-Inh_L2-4_PVALB_C8orf4|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

SOX6 TMEM132C PRRT4 ARHGAP12

1.99e-051843942ba98708dfd7f1b2a661578a334684094ff453ad
ToppCellPrimary_Visual_cortex_(V1C)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_PVALB_1-Inh_L3-4_PVALB_HOMER3|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

SOX6 TMEM132C ARHGAP20 ARHGAP12

2.08e-05186394948815663c212c4311329d503b5991cbbbff9808
ToppCellPrimary_Visual_cortex_(V1C)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_PVALB_1|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

SOX6 TMEM132C ARHGAP20 ARHGAP12

2.21e-0518939478cf414b98bcb19deb934409acddaad1cd51b67f
ToppCellSomatosensory_Cortex_(S1)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_PVALB_1|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

SOX6 TMEM132C PRRT4 ARHGAP12

2.26e-051903943f22c118d552345f731d4d49f0bcb5765d93de3b
ToppCellChildren_(3_yrs)-Endothelial-alveolar_capillary_endothelial_cell_(Cap2;_aerocyte)-D139|Children_(3_yrs) / Lineage, Cell type, age group and donor

LAMA5 SYNPO2 DENND2B PPFIBP1

2.26e-051903940a351609a72fd638c84b2435782e312ee6a33aac
ToppCellPrimary_Visual_cortex_(V1C)-Neuronal-Inh_GABAergic|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

SOX6 TMEM132C PRRT4 ARHGAP12

2.35e-0519239467d6230e32d446dcb12047fae2c3f1faa80dd720
ToppCellfacs-Brain_Non-Myeloid-Cerebellum-3m-Mesenchymal-Pericyte|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LAMA5 SYNPO2 DENND2B VASN

2.55e-05196394184104cbea0461dd2757668ab9755948ac7b585a
ToppCellfacs-Brain_Non-Myeloid-Cerebellum-3m-Mesenchymal-brain_pericyte|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LAMA5 SYNPO2 DENND2B VASN

2.55e-051963948114e98923096c54b6834f21550c3061bab6773d
ToppCell3'-Child09-12-SmallIntestine-Mesenchymal-fibroblastic-Stromal_2_(NPY+)|Child09-12 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

SOX6 LAMA5 SYNPO2 HOXC9

2.65e-05198394d83707b69fb64721ac3cff90ba58cdd999d6b386
ToppCell3'-Pediatric_IBD-SmallIntestine-Mesenchymal-fibroblastic-Stromal_2_(NPY+)|Pediatric_IBD / Celltypes from developing, pediatric, Crohn's, & adult GI tract

SOX6 LAMA5 SYNPO2 DENND2B

2.71e-05199394ec74ff85d6b61013b1f785b2fca343759feb7843
ToppCellmild-B_intermediate|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

FAM167A TNFRSF13B DENND4A TRAK1

2.76e-05200394fe815824e9e4be3f3db73610e3814a7fd533da65
ToppCellfrontal_cortex-Neuronal-GABAergic_neuron-Sst-Sst_Mme_Fam114a1|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

SOX6 TMEM132C PRRT4

1.15e-041083934536cbe1748aee37f0a13648c5679fd592af6322
ToppCellfrontal_cortex-Neuronal-GABAergic_neuron-Sst-Sst_Calb2_Necab1|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

SOX6 TMEM132C PRRT4

1.82e-04126393a4fc7ac4931d2fc8aa8196a62d809b698937aa9c
ToppCellTCGA-Brain-Primary_Tumor-Low_Grade_Glioma-Oligodendroglioma-3|TCGA-Brain / Sample_Type by Project: Shred V9

SOX6 DIP2B ARHGAP12

2.23e-04135393b128596653a5e3b64ed7f657bbfeda35438e2e48
ToppCellControl-Fibroblasts-Mesothelial_FB|Control / group, cell type (main and fine annotations)

TMEM132C SYNPO2 ALPK2

2.43e-04139393e769beb031b262dd92c9605b07dbf3c29fb82520
ToppCellE18.5-samps-Epithelial-Alveolar_epithelial-AT1_-_meso|E18.5-samps / Age Group, Lineage, Cell class and subclass

GRAMD2A LAMA5 TRAK1

2.59e-0414239377fd145c1c500d580f70ac4e54c3fd879ecf0ab3
ToppCelldroplet-Lung-30m-Hematologic-myeloid-Basophil/Mast_cell-basophil_l14|30m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

DENND4A IQCK GATA1

3.16e-041523930fda8980b10ce16179dea92301db74d728f41794
ToppCell368C-Lymphocytic-NK_cells-NK_cell_A|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)

SOX6 DIP2B USP28

3.47e-04157393542944030cd9b3f3559e64f9f6598694d74003c0
ToppCellTCGA-Bladder-Solid_Tissue_Normal|TCGA-Bladder / Sample_Type by Project: Shred V9

TMEM132C SYNPO2 ARHGAP20

3.67e-04160393d6678996e12eaf2b735f1dfae32418cb2fabf268
ToppCellTCGA-Bladder-Solid_Tissue_Normal-Urothelial_normal_tissue-Urothelial_normal_tissue|TCGA-Bladder / Sample_Type by Project: Shred V9

TMEM132C SYNPO2 ARHGAP20

3.67e-041603938a41e2c96e0e170ac35daf6c403bf961b8d7c30b
ToppCellTCGA-Bladder-Solid_Tissue_Normal-Urothelial_normal_tissue|TCGA-Bladder / Sample_Type by Project: Shred V9

TMEM132C SYNPO2 ARHGAP20

3.67e-04160393c8dc575562b463fd30832d322c28006f18f7ab9c
ToppCelldroplet-Marrow-nan-21m-Hematologic-erythroid_progenitor|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FAM167A ARHGAP20 PPFIBP1

3.81e-04162393d0ffebf5adee8a3ac9b81a4b793184f54010489a
ToppCellAdult-Mesenchymal-myofibroblast_cell-D231|Adult / Lineage, Cell type, age group and donor

TMEM132C NR2E3 SYNPO2

3.95e-041643933d8ff70fe5582d1fb56b338be8b76fa1428b3657
ToppCellTCGA-Colorectal-Primary_Tumor-Colorectal_Adenocarcinoma-Mucinous_Colon_Adenocarcinoma|TCGA-Colorectal / Sample_Type by Project: Shred V9

FAM167A PPFIBP1 ALPK2

3.95e-041643933c15e9b8403b03d67f6ecd7861dc19f1261e3244
ToppCellwk_08-11-Mesenchymal-Fibroblast-Alveolar_fibro|wk_08-11 / Celltypes from embryonic and fetal-stage human lung

TMEM132C ARHGAP20 VPS13B

4.09e-0416639365dafed953b01a9830b54309af75c7a561e88336
ToppCellAdult-Mesenchymal-myofibroblast_cell|Adult / Lineage, Cell type, age group and donor

TMEM132C NR2E3 SYNPO2

4.16e-04167393d584a8548a5317bd9686b3be8246ae6ed568796b
ToppCellTCGA-Endometrium-Solid_Tissue_Normal-Endometrium_normal_tissue-Endometrium-7|TCGA-Endometrium / Sample_Type by Project: Shred V9

TMEM132C SYNPO2 ARHGAP20

4.23e-04168393a97e8e07ba949b30805aeed5f60fa5e092b9d3d4
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Mesenchymal-Fibroblast-Collagen+matrisome-high_fibroblast|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

SYNPO2 OXER1 DENND2B

4.38e-04170393fa753cc8fbd04e63c9a303da4dc17ee2ce907f92
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Mesenchymal-Fibroblast-Collagen+matrisome-high_fibroblast-|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

SYNPO2 OXER1 DENND2B

4.38e-0417039303044e1436443b28dd39d5ef4fdb25c18e3a7546
ToppCellControl-Epithelial_cells-ECM-high_epithelial|Control / group, cell type (main and fine annotations)

LAMA5 MECOM PPFIBP1

4.38e-04170393e2023d66e70983c87dacbd6181d3426488d1fc57
ToppCellTCGA-Endometrium-Solid_Tissue_Normal-Endometrium_normal_tissue-Endometrium|TCGA-Endometrium / Sample_Type by Project: Shred V9

TMEM132C SYNPO2 ARHGAP20

4.38e-04170393cdc19013da7c41d1ed8400a6a643e4c684ff9912
ToppCellTCGA-Endometrium-Solid_Tissue_Normal|TCGA-Endometrium / Sample_Type by Project: Shred V9

TMEM132C SYNPO2 ARHGAP20

4.38e-041703930bde0a40440c7fdf7ba89cac8831d4014e7a4807
ToppCellTCGA-Endometrium-Solid_Tissue_Normal-Endometrium_normal_tissue|TCGA-Endometrium / Sample_Type by Project: Shred V9

TMEM132C SYNPO2 ARHGAP20

4.38e-04170393516b38c4ecf6b0b04c5d4f80c510dcc00b328c6f
ToppCell10x_3'_v3-tissue-resident_(10x_3'_v3)-hematologic-hematopoietic_progenitor-erythroid_progenitor_cell|tissue-resident_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

SOX6 MECOM GATA1

4.38e-0417039374bb46826141bd1e80b4ce16e6bbfc770bd427d3
ToppCell10x_3'_v3-tissue-resident_(10x_3'_v3)-hematologic-hematopoietic_progenitor|tissue-resident_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

SOX6 MECOM GATA1

4.38e-041703936592ebe204b43b81c6b6da99e05da72c0983b3fa
ToppCell3'-Child04-06-SmallIntestine-Mesenchymal-fibroblastic-mLTo|Child04-06 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

LAMA5 FOXI2 ALPK2

4.38e-041703937653f1205d4e62abe7e31b1d76f9bbd665e45667
ToppCell3'_v3-lymph-node_spleen-Lymphocytic_T_CD4-T_CD4/CD8|lymph-node_spleen / Manually curated celltypes from each tissue

YTHDC2 DENND4A TUT4

4.46e-041713932e9a20f8980b78325c52065a9c14ab3656267c05
ToppCell356C-Myeloid-Monocyte-CD16+_Monocyte|Monocyte / Donor, Lineage, Cell class and subclass (all cells)

YTHDC2 DDHD2 PPFIBP1

4.53e-041723939dca1542145d88559527db7e0f6ad150df59ca2d
ToppCellwk_08-11-Mesenchymal-Chondrocyte-intermediate_chondrocyte|wk_08-11 / Celltypes from embryonic and fetal-stage human lung

SOX6 MECOM WNK4

4.53e-04172393415d57aa6278b8c12e7a2cf9c3fa5283389fb9b0
ToppCellsystemic_lupus_erythematosus-treated-Lymphocytic_B-B_atypical-female|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex

FAM167A TNFRSF13B VASN

4.61e-0417339323248019c819f6e38337dcc4edb763ef1992e89e
ToppCellsystemic_lupus_erythematosus-treated-Lymphocytic_B-B_atypical|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex

FAM167A TNFRSF13B VASN

4.61e-04173393f135cc9dcf34f33ced3210171ab40ae6d77cfae0
ToppCellPBMC_fresh-frozen-Severe-critical_progression_d03-09-Lymphocytic-Lymphocytic_B-B_cell-B_c04-SOX5-TNFRSF1B|Severe-critical_progression_d03-09 / Compartment, severity and other cell annotations on 10x 3' data (130k)

FAM167A TNFRSF13B TRAK1

4.69e-04174393ebe6ce173ad12d4a2afa39f8d6185c0e4f97fb1e
ToppCellSomatosensory_Cortex_(S1)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_PVALB_1-Inh_L5-6_PVALB_STON2|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

SOX6 TMEM132C PRRT4

4.85e-04176393682a1dfcc507ec540f5fadf08e872533ea9f0291
ToppCellsevere-B_memory|World / disease stage, cell group and cell class

FAM167A LAMA5 TNFRSF13B

4.85e-041763934e5c6b1aa5ffd13593a6bcd1e1253c1737c5c2b4
ToppCell356C-Lymphocytic-NK_cells-NK_cell_A2|NK_cells / Donor, Lineage, Cell class and subclass (all cells)

SOX6 LAMA5 TNFRSF13B

4.85e-04176393052b54c4337ca728974a106b6dbd3b72dd28eb23
ToppCellwk_08-11-Mesenchymal-Chondrocyte|wk_08-11 / Celltypes from embryonic and fetal-stage human lung

SOX6 VASN WNK4

4.85e-041763931af28b701c4598ce761f85adbd5d79e4918d265a
ToppCellPBMC-Mild-cDC_11|Mild / Compartment, Disease Groups and Clusters

GRAMD2A LAMA5 DENND2B

4.93e-04177393974305e4c0eff90134c4e58cf11b955d1eee0501
ToppCellSomatosensory_Cortex_(S1)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_PVALB_1-Inh_L1-3_PVALB_WFDC2|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

SOX6 TMEM132C ASCL5

4.93e-04177393c20df760b25caa772278397b02fc36521927cbfc
ToppCelldroplet-Lung-LUNG-30m-Endothelial-Artery_endothelial_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LAMA5 MECOM PRRT4

5.09e-04179393a09647750eba9d93c5efc1db3b555fefb5eec7b5
ToppCellkidney_cells-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

TMEM132C SYNPO2 ARHGAP20

5.18e-04180393c2746092ef251e9d5910fe96461afdd0624a24c6
ToppCell10x_3'_v3-spleen_(10x_3'_v3)-hematologic-hematopoietic_progenitor|spleen_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

MECOM PRRT4 GATA1

5.18e-04180393f598bb9df0d784120847fada2d9a2a88b8b68cd1
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell-Cortical_Collecting_Duct_Principal_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

MECOM IQCK TRAK1

5.18e-04180393023ec0b080c8a5cd0f36e83c6b17d4be3c01edb5
ToppCellkidney_cells-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast-Adaptive_/_Maladaptive_/_Repairing_Fibroblast|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

TMEM132C SYNPO2 ARHGAP20

5.18e-0418039332c6a3886428d82fb4355d987c6d2645f333447b
ToppCell3'-GW_trimst-2-LargeIntestine-Epithelial-neuro-epithelial-EC_cells_(TAC1+)|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

FAM167A NEUROD1 WNK4

5.18e-04180393d553aba594f5304f1c09ff9c6d49b64cd7ee7850
ToppCell10x_3'_v3-spleen_(10x_3'_v3)-hematologic-hematopoietic_progenitor-hematopoietic_stem_cell|spleen_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

MECOM PRRT4 GATA1

5.18e-04180393b4fa047f271c7b56940bdc85c912f50aa5b5ca82
ToppCellRV|World / Chamber and Cluster_Paper

TMEM132C SYNPO2 PPFIBP1

5.26e-04181393bbe1e6e59d8889bd37d6e8303116cbdcafca7236
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell-Descending_Thin_Limb_Cell_Type_2|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

SOX6 PPFIBP1 ALPK2

5.26e-041813936956ecd6264f7469a25e555673bce4eb97d28f7a
ToppCell3'-GW_trimst-1-SmallIntestine-Epithelial-neuro-epithelial-M/X_cells_(MLN/GHRL+)|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

FAM167A GRAMD2A NEUROD1

5.26e-04181393af031661af28f99d906d8e013b4949133b44a2e6
ToppCellControl-Epithelial_alveolar-AT_1-AT1-AT2|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

SOX6 FAM167A GRAMD2A

5.35e-04182393a95956ce4adccb34cc0c47ebfa1878ce4617904e
ToppCellASK454-Epithelial|ASK454 / Donor, Lineage and Cell class of Lung cells from Dropseq

FAM167A GRAMD2A IQCK

5.35e-04182393ab15316cff989b61ff397a866d7ca8b49c13e981
ToppCellwk_20-22-Hematologic-Meg-ery-Definitive_erythroblast|wk_20-22 / Celltypes from embryonic and fetal-stage human lung

SOX6 DENND4A GATA1

5.35e-041823930c77ef4556c1d1512ebe9077df858b28f9e38dd5
ToppCellfrontal_cortex-Neuronal-GABAergic_neuron|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

SOX6 TMEM132C ARHGAP12

5.35e-04182393f2a1784ffcba9b27132e0db21e574cbd8a0a6418
ToppCellsevere_influenza-B_intermediate|World / disease group, cell group and cell class (v2)

FAM167A GRAMD2A TNFRSF13B

5.35e-04182393e633a908a2fb30ed362cf22fbb8d6839f31f1751
ToppCelldroplet-Lung-30m-Endothelial-arterial_endothelial-pulmonary_artery_endothelial_cell-pulmonary_artery_endothelial_cell_l25|30m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

LAMA5 MECOM PRRT4

5.43e-041833936f8f997ffc9eaebca2683de125b6069d07c07d26
ToppCelldroplet-Lung-30m-Endothelial-arterial_endothelial-pulmonary_artery_endothelial_cell-pulmonary_artery_endothelial_cell_l27|30m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

SOX6 MECOM PRRT4

5.43e-04183393351d575339038bd4a66f408da518c567444208e8
ToppCellAT1-AT2_cells-Donor_02|World / lung cells shred on cell class, cell subclass, sample id

FAM167A GRAMD2A LAMA5

5.43e-041833936821dca076318115d360ff426eb1218cfe104063
ToppCellnucseq-Epithelial-Epithelial_Alveolar-AT1-AT1|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

GRAMD2A LAMA5 MECOM

5.52e-0418439357c792e6e2fedba25d3350ffe649fd74750b579d
ToppCellnucseq-Epithelial-Epithelial_Alveolar-AT1|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

GRAMD2A LAMA5 MECOM

5.52e-04184393d7bd0f0c607bade67c99e9fb3578a570298bf926
ToppCelldroplet-Lung-30m-Endothelial-arterial_endothelial-pulmonary_artery_endothelial_cell|30m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

LAMA5 MECOM PRRT4

5.52e-04184393f506d0ee48f39d6f59f19554217dfdf0987cc405
ToppCelldroplet-Lung-30m-Endothelial-arterial_endothelial|30m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

LAMA5 MECOM PRRT4

5.52e-041843938bcb1c4bc8ffef74338cdade926a94711de93c64
ToppCellChildren_(3_yrs)-Epithelial-alveolar_epithelial_cell_type_1|Children_(3_yrs) / Lineage, Cell type, age group and donor

GRAMD2A LAMA5 PPFIBP1

5.61e-041853931c222f7285d6e3dae0354dc7e853ddc0ea55e63e
ToppCellPND07-28-samps-Mesenchymal-Myofibroblast-myofibroblast_-_mature_-_C|PND07-28-samps / Age Group, Lineage, Cell class and subclass

TMEM132C SYNPO2 DENND2B

5.61e-04185393427176ad9ab8d9511200fb0a132cfd1e835fe35c
ToppCell3'-Broncho-tracheal-Immune_Lymphocytic-Lymphocytic_B-B_cell-B_cells-B_cells_L.1.5.0.1|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

TNFRSF13B DENND4A TUT4

5.61e-04185393e913c64f9b4873443d88dce270f0b7b6d1b4cbce
ToppCellFetal_29-31_weeks-Immune-enucleated_erythrocyte-D088|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

SOX6 DENND4A GATA1

5.61e-04185393e8f7da9641b6cf1db1093b4f301ce828fd3a529c
ToppCellfacs-Brain_Non-Myeloid-Striatum-24m-Mesenchymal-brain_pericyte|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LAMA5 USP28 VASN

5.61e-0418539338486b69c48dc5e1c4e1488208fa8954a973eccb
ToppCellfacs-Limb_Muscle-ForelimbandHindlimb|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PCF11 DENND4A TRAK1

5.61e-04185393eb7d3c1363d5fedc611f9c1a91ea823de251355e
ToppCellsystemic_lupus_erythematosus-managed-Lymphocytic_B-B_atypical-male|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex

FAM167A TNFRSF13B VASN

5.61e-0418539353960307c6710401c3d52a766c3f4704ace9637f
ToppCellprimary_visual_cortex-Neuronal-GABAergic_neuron|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

SOX6 TMEM132C ARHGAP12

5.61e-04185393739260f8abebaf10a5cc49d91726278579e26170
ToppCellfacs-Brain_Non-Myeloid-Striatum-24m-Mesenchymal-Pericyte|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LAMA5 USP28 VASN

5.61e-041853933c28b5ceba3cfdb6f7e32d5b42e03b6a81a7a658
ToppCellCOPD-Lymphoid-B|World / Disease state, Lineage and Cell class

TNFRSF13B DENND4A TUT4

5.61e-0418539322891ed75e25ef30dfa541cb82d85e08ce07e7d9
ToppCell3'-Broncho-tracheal-Immune_Lymphocytic-Lymphocytic_B-B_cell-B_cells|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

TNFRSF13B DENND4A TUT4

5.69e-041863931a1e5d85a5ad90afee234c12a9b54a5e93a8a2f2
ToppCell3'-Broncho-tracheal-Immune_Lymphocytic-Lymphocytic_B-B_cell|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

TNFRSF13B DENND4A TUT4

5.69e-04186393f1366638edaecad5cad6367440f4c693513bed7e
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell-Descending_Thin_Limb_Cell_Type_2|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

SOX6 PPFIBP1 ALPK2

5.69e-041863935c4ffe4e4d5536ae9f8794277fe032c693e7dd56
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Proximal_Tubule_Epithelial_Cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

SOX6 PPFIBP1 ALPK2

5.69e-04186393b87acc80b7baa41681e4ed11d5537b9fbf5832f5
ToppCellPCW_05-06-Mesenchymal-Mesenchymal_fibroblastic-mes_immature_COL13A1^pos_fibro2_(5)|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung

SOX6 TMEM132C MECOM

5.69e-041863937def03dd856b765bd3f493288641981c4f7fd26e
ToppCell10x3'2.3-week_12-13-Mesenchymal_adipo|week_12-13 / cell types per 3 fetal stages;per 3',per 5'

TMEM132C HOXC9 VASN

5.78e-04187393f1d0fc625e0e7881b3f290742fd7148d995eb71e
ToppCell10x3'2.3-week_12-13-Mesenchymal_adipo-stroma|week_12-13 / cell types per 3 fetal stages;per 3',per 5'

TMEM132C HOXC9 VASN

5.78e-0418739302e7246ef5ad41773d14426254e139b156d45c1d
ToppCell10x3'2.3-week_12-13-Mesenchymal_adipo-stroma-adipo-CAR|week_12-13 / cell types per 3 fetal stages;per 3',per 5'

TMEM132C HOXC9 VASN

5.78e-0418739308c73d125e0638c9e9878165bba2442c266c8a48
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Cortical_Thick_Ascending_Limb_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

TMEM132C MECOM WNK4

5.78e-041873937ea8731288e2a99f45e3958590ee1d76f49ae888
ToppCell5'-GW_trimst-2-LymphNode-Endothelial-blood_vessel_EC-Fetal_arterial_EC|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

FOXI2 MECOM IQCK

5.78e-04187393d9d10ed7c905778a29a0dc3ced3eef02a6b1de5c
ToppCellsevere_influenza-B_intermediate|severe_influenza / disease group, cell group and cell class (v2)

FAM167A GRAMD2A TNFRSF13B

5.78e-04187393d6db8595aa72fdabc4a056ba6ce09876868a66d5
ToppCellIPF-Lymphoid-B|Lymphoid / Disease state, Lineage and Cell class

TNFRSF13B DIP2B TRAK1

5.78e-04187393af1327559f7e01bec070881cae52834917c3da65
ToppCellControl-Endothelial-VE_Capillary_A|Control / Disease state, Lineage and Cell class

LAMA5 DENND2B PPFIBP1

5.78e-0418739354d7588172ac145ff5045ad9771636729ca3f0ca
ToppCellPCW_07-8.5-Mesenchymal-Mesenchymal_fibroblastic-mes_immature3_(17)|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

TMEM132C ARHGAP20 PPFIBP1

5.78e-04187393a9316e2818217ec5feae9cf8816f7249803caee6
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell-Outer_Medullary_Collecting_Duct_Principal_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

MECOM IQCK TRAK1

5.78e-04187393e3095455d2f255854f339f6b05fa87852af0700f
ToppCellAT1-AT2_cells-Donor_01|World / lung cells shred on cell class, cell subclass, sample id

FAM167A GRAMD2A PPFIBP1

5.87e-04188393be710bc957118cf426dd71c2d57e6f1b41c9a467
ToppCell5'-Adult-LargeIntestine-Mesenchymal-fibroblastic-Stromal_2_(NPY+)|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

SOX6 LAMA5 DENND2B

5.87e-04188393997dcfc4f08738ab398d8abc15e4fd2fc6619862
Diseasesystolic blood pressure, alcohol consumption measurement

SOX6 FAM167A MECOM

3.32e-0547393EFO_0006335, EFO_0007878
Diseasemultiple myeloma

TNFRSF13B MECOM HERC2

4.40e-04112393EFO_0001378
Diseasediastolic blood pressure, unipolar depression

SOX6 TRAK1

7.23e-0430392EFO_0003761, EFO_0006336
Diseasered blood cell density measurement

SOX6 TNFRSF13B MECOM DENND4A DENND2B VPS13B

9.73e-04880396EFO_0007978
Diseasesmoking status measurement, systolic blood pressure

SOX6 FAM167A MECOM

1.15e-03156393EFO_0006335, EFO_0006527
Diseasepulse pressure measurement

SOX6 LAMA5 DIP2B DDHD2 VASN ARHGAP12 TRAK1

2.09e-031392397EFO_0005763
DiseaseMetastatic melanoma

WNK4 ALPK2

2.33e-0354392C0278883

Protein segments in the cluster

PeptideGeneStartEntry
APSSLVPESSESSCF

ASCL5

251

Q7RTU5
VPESSESSCFSPSPF

ASCL5

256

Q7RTU5
SSPDLTRFPCTSSPE

ALPK2

1601

Q86TB3
DTSPPTCPFKTASFG

DENND2B

86

P78524
SSPAFSPTCPFREES

DENND4A

1281

Q7Z401
DPEFPSSPYSSSSPC

NR2E3

201

Q9Y5X4
PSCSTDSSFTRTPVP

IQCK

16

Q8N0W5
PCSPATSSEAFTPKE

MECOM

46

Q03112
PSCSFAPKPAVFSTS

HOXC9

51

P31274
ESSPDNPFFESSPTT

BLZF1

351

Q9H2G9
SPSCDPFNTSVPEEF

PPFIBP1

386

Q86W92
PSSPGFEDCSSSEAT

HERC2

2421

O95714
QASPSPSAPEAATCF

FOXI2

231

Q6ZQN5
PSPSPNSCSSFELID

DDHD2

16

O94830
FVQSPADACTPPDTS

DIP2B

131

Q9P265
DSSTFDTDTFCPPRP

MIEF1

101

Q9NQG6
TGFPSCYPTPSSSND

LAMA5

466

O15230
PYSSTEPLCSPSESD

PIMREG

186

Q9BSJ6
FSPSPSSAPSAFTTV

OXER1

61

Q8TDS5
TASKPCFPENESSPS

ARHGAP12

436

Q8IWW6
SSFDCTPSPSKTPVE

PCF11

1486

O94913
PDFSSTFFSPTGSPL

GATA1

166

P15976
FESPSIASSIPSEPC

APC2

1171

O95996
PCIPPSSVDSTDSFF

GRAMD2A

226

Q8IUY3
VPSTCSSTFPEELSP

NUMA1

156

Q14980
SCSPTFSSDPLTTPL

MT-ND4

51

P03905
FCDSPLASSFSLSTP

FAM167A

181

Q96KS9
FTPTETSSPIDCTFQ

ARHGAP20

966

Q9P2F6
FTTFTTIPPDDSCPT

TMEM132C

1056

Q8N3T6
DCSSTSASPEPSLPV

SOX6

761

P35712
TSSPPSFEFKCTSPP

TRAK1

791

Q9UPV9
TSPPSFFAEASSPVS

SYNPO2

1031

Q9UMS6
PSPASSPCSDYTVDF

PRRT4

706

C9JH25
FASTKPASESCPPES

USP28

451

Q96RU2
DFGCPATTTTATVPT

VASN

346

Q6EMK4
STSPEPVETCSFCFP

TNFRSF13B

221

O14836
TDSSSYPSPCASPSP

YTHDC2

1256

Q9H6S0
TAPPDTSTCSPSADI

VPS13B

1271

Q7Z7G8
QSSECSESPSYSPQP

TUT4

1416

Q5TAX3
FPPCPSTSSFPSTTA

WNK4

906

Q96J92
FFESPLTDCTSPSFD

NEUROD1

256

Q13562