Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyBiologicalProcess	regulation of developmental growth	SEMA6C CACNA1C ERBB4 ACACB MYCBP2 WNT2 APC ACTN3 DCX STAT5A STAT5B MEGF8 NOTCH1	1.72e-06	421	125	13	GO:0048638
GeneOntologyBiologicalProcess	positive regulation of developmental growth	ERBB4 ACACB WNT2 ACTN3 DCX STAT5A STAT5B MEGF8 NOTCH1	1.49e-05	238	125	9	GO:0048639
GeneOntologyBiologicalProcess	cell cycle process	CDKN2D CDKN3 ERCC6 HUS1B USP29 APC SPO11 YTHDC2 GOLGA6B INO80 ZNF365 SH2B1 CXCR5 PPP1R10 KAT2B SPIN1 HECW2 SUN2 RECQL4 TUBGCP3 PDE4DIP EXOC1 SLX4	1.66e-05	1441	125	23	GO:0022402
GeneOntologyBiologicalProcess	regulation of growth	SEMA6C CACNA1C CDKN2D ERBB4 ACACB MYCBP2 WNT2 APC ACTN3 INO80 DCX STAT5A STAT5B MELTF MEGF8 NOTCH1	1.91e-05	777	125	16	GO:0040008
GeneOntologyBiologicalProcess	negative regulation of erythrocyte differentiation	STAT5A STAT5B HSPA9	3.46e-05	11	125	3	GO:0045647
GeneOntologyBiologicalProcess	developmental growth	COL3A1 SEMA6C CACNA1C ERBB4 ERCC6 ACACB MYCBP2 WNT2 APC EVC EXT1 ACTN3 DCX STAT5A STAT5B MEGF8 NOTCH1	3.59e-05	911	125	17	GO:0048589
GeneOntologyBiologicalProcess	mitotic cell cycle	CDKN2D CDKN3 HUS1B USP29 APC YTHDC2 GOLGA6B INO80 ZNF365 SH2B1 STAT5A STAT5B PPP1R10 KAT2B HECW2 SUN2 TUBGCP3 EXOC1	4.00e-05	1014	125	18	GO:0000278
GeneOntologyBiologicalProcess	positive regulation of growth	ERBB4 ACACB WNT2 ACTN3 INO80 DCX STAT5A STAT5B MEGF8 NOTCH1	4.20e-05	339	125	10	GO:0045927
GeneOntologyBiologicalProcess	growth	COL3A1 SEMA6C CACNA1C CDKN2D ERBB4 ERCC6 ACACB MYCBP2 WNT2 APC EVC EXT1 ACTN3 INO80 DCX STAT5A STAT5B MELTF MEGF8 NOTCH1	5.22e-05	1235	125	20	GO:0040007
GeneOntologyBiologicalProcess	multicellular organismal-level homeostasis	COL3A1 AKT3 ERBB4 NPR3 ERCC6 ACACB DOCK10 APC EXT1 ACTN3 STAT5A STAT5B NLRP6 PASK SCT HSPA9 NOTCH1 DMTN	5.75e-05	1043	125	18	GO:0048871
GeneOntologyBiologicalProcess	muscle organ development	COL3A1 GPC1 MYOM1 WNT2 ZNF689 EVC ABCC9 ACTN3 ZBTB42 EGR3 NOTCH1	7.10e-05	436	125	11	GO:0007517
GeneOntologyBiologicalProcess	regulation of gamma-delta T cell differentiation	STAT5A STAT5B EGR3	9.37e-05	15	125	3	GO:0045586
GeneOntologyBiologicalProcess	body fluid secretion	ERBB4 NPR3 STAT5A STAT5B NLRP6 SCT	9.56e-05	121	125	6	GO:0007589
GeneOntologyBiologicalProcess	central nervous system development	COL3A1 PCSK1 TRNP1 FOXR1 AKT3 ERBB4 MYCBP2 ENPP2 WNT2 SCYL1 LAMC3 EXT1 GRIN2B DCX ZNF365 SUN2 SCT NOTCH1 NOTCH3	1.07e-04	1197	125	19	GO:0007417
GeneOntologyBiologicalProcess	development of secondary male sexual characteristics	STAT5A STAT5B	1.09e-04	3	125	2	GO:0046544
GeneOntologyBiologicalProcess	plasma membrane bounded cell projection morphogenesis	SEMA6C MYCBP2 ENPP2 DOCK10 APC LAMC3 GOLGA6B EXT1 DCX ZNF365 MEGF8 HECW2 NOTCH1 PLXNB1 NOTCH3	1.32e-04	819	125	15	GO:0120039
GeneOntologyBiologicalProcess	regulation of gamma-delta T cell activation	STAT5A STAT5B EGR3	1.39e-04	17	125	3	GO:0046643
GeneOntologyBiologicalProcess	cell projection morphogenesis	SEMA6C MYCBP2 ENPP2 DOCK10 APC LAMC3 GOLGA6B EXT1 DCX ZNF365 MEGF8 HECW2 NOTCH1 PLXNB1 NOTCH3	1.45e-04	826	125	15	GO:0048858
GeneOntologyBiologicalProcess	double-strand break repair via homologous recombination	ERCC6 HUS1B INO80 ZNF365 DMAP1 RECQL4 SLX4	1.51e-04	188	125	7	GO:0000724
GeneOntologyBiologicalProcess	organ growth	CACNA1C ERBB4 ACACB WNT2 APC EVC EXT1 NOTCH1	1.70e-04	256	125	8	GO:0035265
GeneOntologyBiologicalProcess	cell morphogenesis involved in neuron differentiation	SEMA6C MYCBP2 DOCK10 APC LAMC3 GOLGA6B EXT1 DCX ZNF365 MEGF8 HECW2 NOTCH1 PLXNB1 NOTCH3	1.79e-04	748	125	14	GO:0048667
GeneOntologyBiologicalProcess	recombinational repair	ERCC6 HUS1B INO80 ZNF365 DMAP1 RECQL4 SLX4	1.83e-04	194	125	7	GO:0000725
GeneOntologyBiologicalProcess	positive regulation of pancreatic juice secretion	NPR3 SCT	2.17e-04	4	125	2	GO:0090187
GeneOntologyBiologicalProcess	brain development	COL3A1 PCSK1 TRNP1 FOXR1 AKT3 ERBB4 WNT2 EXT1 GRIN2B DCX ZNF365 SUN2 SCT NOTCH1 NOTCH3	2.21e-04	859	125	15	GO:0007420
GeneOntologyBiologicalProcess	gamma-delta T cell differentiation	STAT5A STAT5B EGR3	2.30e-04	20	125	3	GO:0042492
GeneOntologyBiologicalProcess	regulation of organ growth	CACNA1C ERBB4 ACACB WNT2 APC NOTCH1	2.38e-04	143	125	6	GO:0046620
GeneOntologyBiologicalProcess	artery morphogenesis	COL3A1 AKT3 MEGF8 NOTCH1 NOTCH3	2.43e-04	92	125	5	GO:0048844
GeneOntologyBiologicalProcess	meiotic cell cycle	PMS2 HUS1B SPO11 YTHDC2 GOLGA6B SPIN1 SUN2 TUBGCP3 SLX4	2.86e-04	350	125	9	GO:0051321
GeneOntologyBiologicalProcess	positive regulation of cell development	ENPP2 WNT2 GOLGA6B ACTN3 DCX ZNF365 STAT5A STAT5B MEGF8 EGR3 NOTCH1 PLXNB1	3.59e-04	614	125	12	GO:0010720
GeneOntologyBiologicalProcess	neuron projection morphogenesis	SEMA6C MYCBP2 DOCK10 APC LAMC3 GOLGA6B EXT1 DCX ZNF365 MEGF8 HECW2 NOTCH1 PLXNB1 NOTCH3	3.63e-04	802	125	14	GO:0048812
GeneOntologyBiologicalProcess	DNA recombination	PMS2 ERCC6 HUS1B SPO11 INO80 ZNF365 DMAP1 RECQL4 SLX4	4.13e-04	368	125	9	GO:0006310
GeneOntologyBiologicalProcess	head development	COL3A1 PCSK1 TRNP1 FOXR1 AKT3 ERBB4 WNT2 EXT1 GRIN2B DCX ZNF365 SUN2 SCT NOTCH1 NOTCH3	4.52e-04	919	125	15	GO:0060322
GeneOntologyBiologicalProcess	positive regulation of heart growth	ERBB4 ACACB WNT2 NOTCH1	4.82e-04	60	125	4	GO:0060421
GeneOntologyBiologicalProcess	regulation of heart growth	ERBB4 ACACB WNT2 APC NOTCH1	4.90e-04	107	125	5	GO:0060420
Domain	FH	FOXR1 FOXD4L6 FOXD4L5 FOXD4L4 FOXD4L3 FOXD4	9.22e-07	49	126	6	SM00339
Domain	FORK_HEAD_1	FOXR1 FOXD4L6 FOXD4L5 FOXD4L4 FOXD4L3 FOXD4	9.22e-07	49	126	6	PS00657
Domain	FORK_HEAD_2	FOXR1 FOXD4L6 FOXD4L5 FOXD4L4 FOXD4L3 FOXD4	9.22e-07	49	126	6	PS00658
Domain	Fork_head_dom	FOXR1 FOXD4L6 FOXD4L5 FOXD4L4 FOXD4L3 FOXD4	9.22e-07	49	126	6	IPR001766
Domain	FORK_HEAD_3	FOXR1 FOXD4L6 FOXD4L5 FOXD4L4 FOXD4L3 FOXD4	9.22e-07	49	126	6	PS50039
Domain	Forkhead	FOXR1 FOXD4L6 FOXD4L5 FOXD4L4 FOXD4L3 FOXD4	9.22e-07	49	126	6	PF00250
Domain	TF_fork_head_CS_2	FOXD4L6 FOXD4L5 FOXD4L4 FOXD4L3 FOXD4	1.42e-05	46	126	5	IPR030456
Domain	TF_fork_head_CS_1	FOXD4L6 FOXD4L5 FOXD4L4 FOXD4L3 FOXD4	1.58e-05	47	126	5	IPR018122
Domain	DUF3454	NOTCH1 NOTCH3	1.35e-04	3	126	2	PF11936
Domain	DUF3454_notch	NOTCH1 NOTCH3	1.35e-04	3	126	2	IPR024600
Domain	DUF3454	NOTCH1 NOTCH3	1.35e-04	3	126	2	SM01334
Domain	Notch	NOTCH1 NOTCH3	2.69e-04	4	126	2	IPR008297
Domain	NODP	NOTCH1 NOTCH3	2.69e-04	4	126	2	PF07684
Domain	Notch_NODP_dom	NOTCH1 NOTCH3	2.69e-04	4	126	2	IPR011656
Domain	Notch_NOD_dom	NOTCH1 NOTCH3	2.69e-04	4	126	2	IPR010660
Domain	NOD	NOTCH1 NOTCH3	2.69e-04	4	126	2	PF06816
Domain	NOD	NOTCH1 NOTCH3	2.69e-04	4	126	2	SM01338
Domain	NODP	NOTCH1 NOTCH3	2.69e-04	4	126	2	SM01339
Domain	LNR	NOTCH1 NOTCH3	4.46e-04	5	126	2	PS50258
Domain	-	FOXR1 SPO11 FOXD4L6 FOXD4L5 FOXD4L4 FOXD4L3 FOXD4	7.00e-04	218	126	7	1.10.10.10
Domain	STAT_TF_DNA-bd_sub	STAT5A STAT5B	9.27e-04	7	126	2	IPR012345
Domain	STAT	STAT5A STAT5B	9.27e-04	7	126	2	IPR001217
Domain	STAT_int	STAT5A STAT5B	9.27e-04	7	126	2	SM00964
Domain	STAT_TF_DNA-bd	STAT5A STAT5B	9.27e-04	7	126	2	IPR013801
Domain	STAT_bind	STAT5A STAT5B	9.27e-04	7	126	2	PF02864
Domain	STAT_int	STAT5A STAT5B	9.27e-04	7	126	2	PF02865
Domain	Notch_dom	NOTCH1 NOTCH3	9.27e-04	7	126	2	IPR000800
Domain	-	STAT5A STAT5B	9.27e-04	7	126	2	1.10.532.10
Domain	STAT_alpha	STAT5A STAT5B	9.27e-04	7	126	2	PF01017
Domain	-	STAT5A STAT5B	9.27e-04	7	126	2	1.20.1050.20
Domain	STAT_TF_prot_interaction	STAT5A STAT5B	9.27e-04	7	126	2	IPR013799
Domain	STAT_TF_coiled-coil	STAT5A STAT5B	9.27e-04	7	126	2	IPR015988
Domain	-	STAT5A STAT5B	9.27e-04	7	126	2	2.60.40.630
Domain	Notch	NOTCH1 NOTCH3	9.27e-04	7	126	2	PF00066
Domain	NL	NOTCH1 NOTCH3	9.27e-04	7	126	2	SM00004
Domain	STAT_TF_alpha	STAT5A STAT5B	1.23e-03	8	126	2	IPR013800
Domain	WHTH_DNA-bd_dom	FOXR1 SPO11 FOXD4L6 FOXD4L5 FOXD4L4 FOXD4L3 FOXD4	1.29e-03	242	126	7	IPR011991
Domain	Plexin_repeat	SEMA6C MEGF8 PLXNB1	1.29e-03	32	126	3	IPR002165
Domain	PSI	SEMA6C MEGF8 PLXNB1	1.29e-03	32	126	3	PF01437
Domain	BTB	ZBTB42 KLHL11 KCNG2 KCTD3 GAN SLX4	1.40e-03	180	126	6	SM00225
Domain	Patatin	PNPLA4 PNPLA6	1.58e-03	9	126	2	PF01734
Domain	PNPLA	PNPLA4 PNPLA6	1.58e-03	9	126	2	PS51635
Domain	Patatin/PLipase_A2-rel	PNPLA4 PNPLA6	1.58e-03	9	126	2	IPR002641
Domain	BTB/POZ_dom	ZBTB42 KLHL11 KCNG2 KCTD3 GAN SLX4	1.61e-03	185	126	6	IPR000210
Domain	SKP1/BTB/POZ	ZBTB42 KLHL11 KCNG2 KCTD3 GAN SLX4	1.79e-03	189	126	6	IPR011333
Domain	PSI	SEMA6C MEGF8 PLXNB1	3.24e-03	44	126	3	IPR016201
Domain	PSI	SEMA6C MEGF8 PLXNB1	3.68e-03	46	126	3	SM00423
Domain	Growth_fac_rcpt_	ERBB4 LAMC3 MEGF8 NOTCH1 NOTCH3	4.14e-03	156	126	5	IPR009030
Domain	-	KLHL11 MEGF8 GAN	4.16e-03	48	126	3	2.120.10.80
Domain	FH2	GRID2IP FHOD1	4.48e-03	15	126	2	PS51444
Domain	FH2_Formin	GRID2IP FHOD1	4.48e-03	15	126	2	IPR015425
Domain	FH2	GRID2IP FHOD1	4.48e-03	15	126	2	PF02181
Domain	FH2	GRID2IP FHOD1	4.48e-03	15	126	2	SM00498
Domain	BTB	ZBTB42 KLHL11 KCTD3 GAN SLX4	4.61e-03	160	126	5	PS50097
Domain	Acyl_Trfase/lysoPLipase	PNPLA4 PNPLA6	5.75e-03	17	126	2	IPR016035
Domain	Helicase_C	ERCC6 YTHDC2 INO80 RECQL4	5.97e-03	107	126	4	PF00271
Domain	HELICc	ERCC6 YTHDC2 INO80 RECQL4	5.97e-03	107	126	4	SM00490
Domain	Kelch-typ_b-propeller	KLHL11 MEGF8 GAN	6.09e-03	55	126	3	IPR015915
Domain	Helicase_C	ERCC6 YTHDC2 INO80 RECQL4	6.17e-03	108	126	4	IPR001650
Domain	ZINC_FINGER_C2H2_2	DUSP12 ZNF165 ZNF689 ZNF696 ZNF442 ZNF865 ZBTB42 RBSN EGR3 MZF1 EGR4 HELZ2	6.18e-03	775	126	12	PS50157
Domain	HELICASE_CTER	ERCC6 YTHDC2 INO80 RECQL4	6.37e-03	109	126	4	PS51194
Domain	HELICASE_ATP_BIND_1	ERCC6 YTHDC2 INO80 RECQL4	6.37e-03	109	126	4	PS51192
Domain	DEXDc	ERCC6 YTHDC2 INO80 RECQL4	6.37e-03	109	126	4	SM00487
Domain	Helicase_ATP-bd	ERCC6 YTHDC2 INO80 RECQL4	6.58e-03	110	126	4	IPR014001
Pathway	REACTOME_SIGNALING_BY_LEPTIN	SH2B1 STAT5A STAT5B	4.27e-05	11	92	3	M27195
Pathway	PID_ERBB4_PATHWAY	ERBB4 GRIN2B STAT5A STAT5B	1.06e-04	38	92	4	M13
Pathway	REACTOME_PROLACTIN_RECEPTOR_SIGNALING	SH2B1 STAT5A STAT5B	1.16e-04	15	92	3	M552
Pathway	REACTOME_GROWTH_HORMONE_RECEPTOR_SIGNALING	SH2B1 STAT5A STAT5B	1.42e-04	16	92	3	MM15710
Pubmed	Neural transcription factors bias cleavage stage blastomeres to give rise to neural ectoderm.	FOXD4L6 FOXD4L5 FOXD4L4 FOXD4L3 FOXD4	3.88e-12	6	129	5	27092474
Pubmed	Expression of the winged helix genes fkh-4 and fkh-5 defines domains in the central nervous system.	SCYL1 FOXD4L6 FOXD4L5 FOXD4L4 FOXD4L3 FOXD4	1.80e-11	16	129	6	8861101
Pubmed	The mouse fkh-2 gene. Implications for notochord, foregut, and midbrain regionalization.	FOXD4L6 FOXD4L5 FOXD4L4 FOXD4L3 FOXD4	3.60e-11	8	129	5	8530406
Pubmed	An amphioxus winged helix/forkhead gene, AmphiFoxD: insights into vertebrate neural crest evolution.	FOXD4L6 FOXD4L5 FOXD4L4 FOXD4L3 FOXD4	8.08e-11	9	129	5	12412011
Pubmed	A genetic study of the suppressors of the Engrailed-1 cerebellar phenotype.	FOXD4L6 FOXD4L5 FOXD4L4 FOXD4L3 FOXD4	8.16e-10	13	129	5	16884697
Pubmed	Cloning and characterization of seven human forkhead proteins: binding site specificity and DNA bending.	FOXD4L6 FOXD4L5 FOXD4L4 FOXD4L3 FOXD4	8.16e-10	13	129	5	7957066
Pubmed	FOXD4a and FOXD4b, two new winged helix transcription factors, are expressed in human leukemia cell lines.	FOXD4L6 FOXD4L5 FOXD4L4 FOXD4	9.01e-10	5	129	4	12234674
Pubmed	Six members of the mouse forkhead gene family are developmentally regulated.	FOXD4L6 FOXD4L5 FOXD4L4 FOXD4L3 FOXD4	1.89e-09	15	129	5	7689224
Pubmed	Strain-specific modifier genes of Cecr2-associated exencephaly in mice: genetic analysis and identification of differentially expressed candidate genes.	FOXD4L6 FOXD4L5 FOXD4L4 FOXD4L3 FOXD4	1.89e-09	15	129	5	22045912
Pubmed	Developmental competence of the gut endoderm: genetic potentiation by GATA and HNF3/fork head proteins.	FOXD4L6 FOXD4L5 FOXD4L4 FOXD4L3 FOXD4	2.74e-09	16	129	5	10208738
Pubmed	Functional equivalency between Otx2 and Otx1 in development of the rostral head.	FOXD4L6 FOXD4L5 FOXD4L4 FOXD4L3 FOXD4	7.24e-09	19	129	5	9895322
Pubmed	Forkhead transcription factor Foxf2 (LUN)-deficient mice exhibit abnormal development of secondary palate.	FOXD4L6 FOXD4L5 FOXD4L4 FOXD4L3 FOXD4	9.63e-09	20	129	5	12812790
Pubmed	Sequential roles for Otx2 in visceral endoderm and neuroectoderm for forebrain and midbrain induction and specification.	FOXD4L6 FOXD4L5 FOXD4L4 FOXD4L3 FOXD4	1.26e-08	21	129	5	9449667
Pubmed	Crucial roles of Foxa2 in mouse anterior-posterior axis polarization via regulation of anterior visceral endoderm-specific genes.	FOXD4L6 FOXD4L5 FOXD4L4 FOXD4L3 FOXD4	1.63e-08	22	129	5	17389379
Pubmed	Otx2 is required to respond to signals from anterior neural ridge for forebrain specification.	FOXD4L6 FOXD4L5 FOXD4L4 FOXD4L3 FOXD4	2.61e-08	24	129	5	11820816
Pubmed	A Requirement for Zic2 in the Regulation of Nodal Expression Underlies the Establishment of Left-Sided Identity.	FOXD4L6 FOXD4L5 FOXD4L4 FOXD4L3 FOXD4	2.61e-08	24	129	5	29992973
Pubmed	Ssdp1 regulates head morphogenesis of mouse embryos by activating the Lim1-Ldb1 complex.	FOXD4L6 FOXD4L5 FOXD4L4 FOXD4L3 FOXD4	4.01e-08	26	129	5	15857913
Pubmed	Molecular profiling of synovial joints: use of microarray analysis to identify factors that direct the development of the knee and elbow.	FOXD4L6 FOXD4L5 FOXD4L4 FOXD4L3 FOXD4	7.18e-08	29	129	5	22972626
Pubmed	Genome-scale study of transcription factor expression in the branching mouse lung.	FOXD4L6 FOXD4L5 KAT2B FOXD4L4 FOXD4L3 FOXD4	1.92e-07	67	129	6	22711520
Pubmed	The origin of the ankyrin repeat region in Notch intracellular domains is critical for regulation of HES promoter activity.	KAT2B NOTCH1 NOTCH3	9.89e-07	6	129	3	11404076
Pubmed	Chr21 protein-protein interactions: enrichment in proteins involved in intellectual disability, autism, and late-onset Alzheimer's disease.	PMS2 CFAP91 MYCBP2 ENPP2 APC GRIN2B ZNF365 SH2B1 XAB2 STAT5B DMAP1 SBNO1 PDE4DIP MIGA1 EXOC1 MTUS2 SLX4 HSPA9	1.33e-06	1285	129	18	35914814
Pubmed	ESCPE-1 mediates retrograde endosomal sorting of the SARS-CoV-2 host factor Neuropilin-1.	COL3A1 GPC1 NPR3 MYCBP2 LAMC3 EXT1 DMAP1 KLHL11 MELTF PXDN MEGF8 SUN2 FHOD1 PPP6R2 NOTCH1 PLXNB1 NOTCH3	2.34e-06	1201	129	17	35696571
Pubmed	A Lys644Glu substitution in fibroblast growth factor receptor 3 (FGFR3) causes dwarfism in mice by activation of STATs and ink4 cell cycle inhibitors.	CDKN2D STAT5A STAT5B	2.75e-06	8	129	3	9887329
Pubmed	A dual-activity topoisomerase complex regulates mRNA translation and turnover.	SEMA6C TRNP1 MYCBP2 LAMC3 TOR4A INO80 ZNF865 ZBTB42 REXO1 TNRC18 PNPLA6 MEGF8 UCKL1 HELZ2 RGL2 NOTCH1	3.58e-06	1105	129	16	35748872
Pubmed	Structure of the mouse Stat 3/5 locus: evolution from Drosophila to zebrafish to mouse.	GHDC STAT5A STAT5B	5.87e-06	10	129	3	11161808
Pubmed	EB1 acetylation by P300/CBP-associated factor (PCAF) ensures accurate kinetochore-microtubule interactions in mitosis.	APC KAT2B MTUS2	5.87e-06	10	129	3	23001180
Pubmed	Gene content and function of the ancestral chromosome fusion site in human chromosome 2q13-2q14.1 and paralogous regions.	FOXD4L4 FOXD4L3 FOXD4	8.05e-06	11	129	3	12421752
Pubmed	Definitive evidence using enucleated cytoplasts for a nongenomic basis for the cystic change in endoplasmic reticulum structure caused by STAT5a/b siRNAs.	STAT5A STAT5B	1.37e-05	2	129	2	23151802
Pubmed	Signal transducer and activator of transcription 5 (STAT5) paralog dose governs T cell effector and regulatory functions.	STAT5A STAT5B	1.37e-05	2	129	2	26999798
Pubmed	Notch1 counteracts WNT/β-catenin signaling through chromatin modification in colorectal cancer.	APC NOTCH1	1.37e-05	2	129	2	22863622
Pubmed	A Mouse Model to Assess STAT3 and STAT5A/B Combined Inhibition in Health and Disease Conditions.	STAT5A STAT5B	1.37e-05	2	129	2	31443474
Pubmed	Interleukin-2 family cytokines stimulate phosphorylation of the Pro-Ser-Pro motif of Stat5 transcription factors in human T cells: resistance to suppression of multiple serine kinase pathways.	STAT5A STAT5B	1.37e-05	2	129	2	12377952
Pubmed	A novel Ncr1-Cre mouse reveals the essential role of STAT5 for NK-cell survival and development.	STAT5A STAT5B	1.37e-05	2	129	2	21127177
Pubmed	The gammac-cytokine regulated transcription factor, STAT5, increases HIV-1 production in primary CD4 T cells.	STAT5A STAT5B	1.37e-05	2	129	2	16289657
Pubmed	Inhibition of Stat5a/b Enhances Proteasomal Degradation of Androgen Receptor Liganded by Antiandrogens in Prostate Cancer.	STAT5A STAT5B	1.37e-05	2	129	2	25552366
Pubmed	Deletion of STAT5a/b in vascular smooth muscle abrogates the male bias in hypoxic pulmonary hypertension in mice: implications in the human disease.	STAT5A STAT5B	1.37e-05	2	129	2	25470773
Pubmed	Post-transcriptional Wnt Signaling Governs Epididymal Sperm Maturation.	APC CCNYL1	1.37e-05	2	129	2	26590424
Pubmed	Constitutively active Stat5A and Stat5B promote adipogenesis.	STAT5A STAT5B	1.37e-05	2	129	2	21431790
Pubmed	Stat5 Is Required for CD103+ Dendritic Cell and Alveolar Macrophage Development and Protection from Lung Injury.	STAT5A STAT5B	1.37e-05	2	129	2	28500076
Pubmed	STAT5 isoforms regulate colorectal cancer cell apoptosis via reduction of mitochondrial membrane potential and generation of reactive oxygen species.	STAT5A STAT5B	1.37e-05	2	129	2	21826656
Pubmed	Interleukin-3, granulocyte-macrophage colony stimulating factor and interleukin-5 transduce signals through two STAT5 homologs.	STAT5A STAT5B	1.37e-05	2	129	2	7720707
Pubmed	STAT5A and STAT5B have opposite correlations with drug response gene expression.	STAT5A STAT5B	1.37e-05	2	129	2	27264955
Pubmed	Nongenomic STAT5-dependent effects on Golgi apparatus and endoplasmic reticulum structure and function.	STAT5A STAT5B	1.37e-05	2	129	2	22159083
Pubmed	STAT5 requires the N-domain for suppression of miR15/16, induction of bcl-2, and survival signaling in myeloproliferative disease.	STAT5A STAT5B	1.37e-05	2	129	2	20008792
Pubmed	STAT5 Regulation of Sex-Dependent Hepatic CpG Methylation at Distal Regulatory Elements Mapping to Sex-Biased Genes.	STAT5A STAT5B	1.37e-05	2	129	2	33199496
Pubmed	The influence of STAT5 antisense oligodeoxynucleotides on the proliferation and apoptosis of selected human cutaneous T-cell lymphoma cell lines.	STAT5A STAT5B	1.37e-05	2	129	2	16502315
Pubmed	Stat5: an essential regulator of mast cell biology.	STAT5A STAT5B	1.37e-05	2	129	2	12217382
Pubmed	Brain STAT5 Modulates Long-Term Metabolic and Epigenetic Changes Induced by Pregnancy and Lactation in Female Mice.	STAT5A STAT5B	1.37e-05	2	129	2	31599926
Pubmed	DNA binding site selection of dimeric and tetrameric Stat5 proteins reveals a large repertoire of divergent tetrameric Stat5a binding sites.	STAT5A STAT5B	1.37e-05	2	129	2	10594041
Pubmed	Mitochondrial translocation of signal transducer and activator of transcription 5 (STAT5) in leukemic T cells and cytokine-stimulated cells.	STAT5A STAT5B	1.37e-05	2	129	2	21036145
Pubmed	Stimulation of lipolysis but not of leptin release by growth hormone is abolished in adipose tissue from Stat5a and b knockout mice.	STAT5A STAT5B	1.37e-05	2	129	2	10486277
Pubmed	A protein (ORF2) encoded by the latency-related gene of bovine herpesvirus 1 interacts with Notch1 and Notch3.	NOTCH1 NOTCH3	1.37e-05	2	129	2	21191019
Pubmed	Defective sister-chromatid cohesion, aneuploidy and cancer predisposition in a mouse model of type II Rothmund-Thomson syndrome.	APC RECQL4	1.37e-05	2	129	2	15703196
Pubmed	Identification of human STAT5-dependent gene regulatory elements based on interspecies homology.	STAT5A STAT5B	1.37e-05	2	129	2	16840779
Pubmed	The role of the STAT5 proteins in the proliferation and apoptosis of the CML and AML cells.	STAT5A STAT5B	1.37e-05	2	129	2	15128421
Pubmed	STAT5 deficiency in hepatocytes reduces diethylnitrosamine-induced liver tumorigenesis in mice.	STAT5A STAT5B	1.37e-05	2	129	2	30377054
Pubmed	Gain-of-function of Stat5 leads to excessive granulopoiesis and lethal extravasation of granulocytes to the lung.	STAT5A STAT5B	1.37e-05	2	129	2	23565285
Pubmed	Assessment of STAT5 as a potential therapy target in enzalutamide-resistant prostate cancer.	STAT5A STAT5B	1.37e-05	2	129	2	32790723
Pubmed	In vivo identification of novel STAT5 target genes.	STAT5A STAT5B	1.37e-05	2	129	2	18492722
Pubmed	Distinctive roles of STAT5a and STAT5b in sexual dimorphism of hepatic P450 gene expression. Impact of STAT5a gene disruption.	STAT5A STAT5B	1.37e-05	2	129	2	10066807
Pubmed	Molecular characterization of STAT5A- and STAT5B-encoding genes reveals extended intragenic sequence homogeneity in cattle and mouse and different degrees of divergent evolution of various domains.	STAT5A STAT5B	1.37e-05	2	129	2	10835485
Pubmed	Loss of Adipocyte STAT5 Confers Increased Depot-Specific Adiposity in Male and Female Mice That Is Not Associated With Altered Adipose Tissue Lipolysis.	STAT5A STAT5B	1.37e-05	2	129	2	35464049
Pubmed	Loss of cytokine-STAT5 signaling in the CNS and pituitary gland alters energy balance and leads to obesity.	STAT5A STAT5B	1.37e-05	2	129	2	18286195
Pubmed	Differentiating the roles of STAT5B and STAT5A in human CD4+ T cells.	STAT5A STAT5B	1.37e-05	2	129	2	23773921
Pubmed	Cloning of human Stat5B. Reconstitution of interleukin-2-induced Stat5A and Stat5B DNA binding activity in COS-7 cells.	STAT5A STAT5B	1.37e-05	2	129	2	8631883
Pubmed	Stat5 is essential for the myelo- and lymphoproliferative disease induced by TEL/JAK2.	STAT5A STAT5B	1.37e-05	2	129	2	11030348
Pubmed	Association between STAT5 polymorphisms and glioblastoma risk in Han Chinese population.	STAT5A STAT5B	1.37e-05	2	129	2	24878107
Pubmed	Regulation of eosinophil apoptosis by nitric oxide: Role of c-Jun-N-terminal kinase and signal transducer and activator of transcription 5.	STAT5A STAT5B	1.37e-05	2	129	2	12847485
Pubmed	Stat5 synergizes with T cell receptor/antigen stimulation in the development of lymphoblastic lymphoma.	STAT5A STAT5B	1.37e-05	2	129	2	12835478
Pubmed	Cloning and expression of Stat5 and an additional homologue (Stat5b) involved in prolactin signal transduction in mouse mammary tissue.	STAT5A STAT5B	1.37e-05	2	129	2	7568026
Pubmed	Identification of STAT5A and STAT5B target genes in human T cells.	STAT5A STAT5B	1.37e-05	2	129	2	24497979
Pubmed	Role of STAT5a in regulation of sex-specific gene expression in female but not male mouse liver revealed by microarray analysis.	STAT5A STAT5B	1.37e-05	2	129	2	17536022
Pubmed	STAT5 transcriptional activity is impaired by LIF in a mammary epithelial cell line.	STAT5A STAT5B	1.37e-05	2	129	2	17382296
Pubmed	STAT5 is essential for Akt/p70S6 kinase activity during IL-2-induced lymphocyte proliferation.	STAT5A STAT5B	1.37e-05	2	129	2	17911616
Pubmed	STAT5 signaling in sexually dimorphic gene expression and growth patterns.	STAT5A STAT5B	1.37e-05	2	129	2	10486314
Pubmed	The transcription factors Stat5a/b are not required for islet development but modulate pancreatic beta-cell physiology upon aging.	STAT5A STAT5B	1.37e-05	2	129	2	17599554
Pubmed	MiR-21 is under control of STAT5 but is dispensable for mammary development and lactation.	STAT5A STAT5B	1.37e-05	2	129	2	24497923
Pubmed	Distinct roles for Notch1 and Notch3 in human adipose-derived stem/stromal cell adipogenesis.	NOTCH1 NOTCH3	1.37e-05	2	129	2	33021719
Pubmed	A novel mouse model of PMS2 founder mutation that causes mismatch repair defect due to aberrant splicing.	PMS2 APC	1.37e-05	2	129	2	34489406
Pubmed	Constitutive activation of STAT5A and STAT5B regulates IgM secretion in Waldenstrom's macroglobulinemia.	STAT5A STAT5B	1.37e-05	2	129	2	24335105
Pubmed	Brain STAT5 signaling modulates learning and memory formation.	STAT5A STAT5B	1.37e-05	2	129	2	29460051
Pubmed	Nonoverlapping functions for Notch1 and Notch3 during murine steady-state thymic lymphopoiesis.	NOTCH1 NOTCH3	1.37e-05	2	129	2	21768299
Pubmed	STAT5 deletion in macrophages alters ductal elongation and branching during mammary gland development.	STAT5A STAT5B	1.37e-05	2	129	2	28606561
Pubmed	Activation of NOTCH1 or NOTCH3 signaling skews human airway basal cell differentiation toward a secretory pathway.	NOTCH1 NOTCH3	1.37e-05	2	129	2	25700162
Pubmed	ERBB4/HER4 potentiates STAT5A transcriptional activity by regulating novel STAT5A serine phosphorylation events.	ERBB4 STAT5A	1.37e-05	2	129	2	15863494
Pubmed	Cell intrinsic defects in cytokine responsiveness of STAT5-deficient hematopoietic stem cells.	STAT5A STAT5B	1.37e-05	2	129	2	12393407
Pubmed	The structure of human STAT5A and B genes reveals two regions of nearly identical sequence and an alternative tissue specific STAT5B promoter.	STAT5A STAT5B	1.37e-05	2	129	2	12039059
Pubmed	Evidence of Notch pathway activation in the ectatic ducts of chronic pancreatitis.	NOTCH1 NOTCH3	1.37e-05	2	129	2	18069660
Pubmed	Differential changes in responses of hypothalamic and brainstem neuronal populations to prolactin during lactation in the mouse.	STAT5A STAT5B	1.37e-05	2	129	2	21178171
Pubmed	Stat5 promotes metastatic behavior of human prostate cancer cells in vitro and in vivo.	STAT5A STAT5B	1.37e-05	2	129	2	20233708
Pubmed	Involvement of the STAT5 signaling pathway in the regulation of mouse preimplantation development.	STAT5A STAT5B	1.37e-05	2	129	2	16775227
Pubmed	STAT5 isoforms: controversies and clarifications.	STAT5A STAT5B	1.37e-05	2	129	2	17447893
Pubmed	Notch1 and Notch3 coordinate for pericyte-induced stabilization of vasculature.	NOTCH1 NOTCH3	1.37e-05	2	129	2	34878922
Pubmed	Activation of signal transducer and activator of transcription-5 in prostate cancer predicts early recurrence.	STAT5A STAT5B	1.37e-05	2	129	2	16115927
Pubmed	Sequential activation of genetic programs in mouse mammary epithelium during pregnancy depends on STAT5A/B concentration.	STAT5A STAT5B	1.37e-05	2	129	2	23275557
Pubmed	Age-associated changes in functional response to CXCR3 and CXCR5 chemokine receptors in human osteoblasts.	CXCR3 CXCR5	1.37e-05	2	129	2	14618028
Pubmed	Granulocyte-macrophage colony-stimulating factor (GM-CSF)-induced STAT5 activation and target-gene expression during human monocyte/macrophage differentiation.	STAT5A STAT5B	1.37e-05	2	129	2	11867689
Pubmed	Global analysis of IL-2 target genes: identification of chromosomal clusters of expressed genes.	STAT5A STAT5B	1.37e-05	2	129	2	15980098
Pubmed	Inactivation of Stat5 in mouse mammary epithelium during pregnancy reveals distinct functions in cell proliferation, survival, and differentiation.	STAT5A STAT5B	1.37e-05	2	129	2	15340066
Pubmed	STAT5A/B gene locus undergoes amplification during human prostate cancer progression.	STAT5A STAT5B	1.37e-05	2	129	2	23660011
Interaction	WNT2 interactions	GPC1 WNT2 PASK PPP6R2 NOTCH1	2.82e-07	23	127	5	int:WNT2
Interaction	ANKRD44 interactions	USP6 SUN2 PPP6R2 NOTCH1 NOTCH3	1.27e-05	48	127	5	int:ANKRD44
Interaction	PASK interactions	WNT2 FOXD4L6 PASK RECQL4 PRR14L THAP12 FOXD4	2.26e-05	134	127	7	int:PASK
Cytoband	9q21.11	FOXD4L6 FOXD4L5 FOXD4L4 FOXD4L3	1.54e-06	30	129	4	9q21.11
Cytoband	7p22.1	PMS2CL TNRC18 GRID2IP	3.21e-04	47	129	3	7p22.1
Cytoband	Ensembl 112 genes in cytogenetic band chr7p22	PMS2 PMS2CL TNRC18 GRID2IP	5.76e-04	134	129	4	chr7p22
GeneFamily	CD molecules\|C-X-C motif chemokine receptors	CXCR3 CXCR5	3.39e-04	6	87	2	1094
GeneFamily	Patatin like phospholipase domain containing	PNPLA4 PNPLA6	1.00e-03	10	87	2	466
Coexpression	MORI_MATURE_B_LYMPHOCYTE_UP	MYCBP2 FOXD4L6 FOXD4L5 CXCR5 FOXD4L4 FOXD4L3 FOXD4	9.66e-07	106	129	7	MM595
Coexpression	PKCA_DN.V1_UP	CYP11A1 ZNF865 PASK PRODH2 EGR3 EGR4 PPP6R2	1.42e-05	159	129	7	M2755
Coexpression	FAN_EMBRYONIC_CTX_BIG_GROUPS_INHIBITORY	ERBB4 DCX PDE4DIP	2.48e-05	12	129	3	M39023
ToppCell	droplet-Fat-Bat-18m-Endothelial-endothelial_cell\|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PCSK1 ADCY4 ACACB FBXL8 NEU3 EGR3 HECW2 PLXNB1	5.43e-08	179	129	8	e6224864eb76a2e9c1fc0c61513d9e936bb5c72c
ToppCell	droplet-Fat-Bat-18m-Endothelial-nan\|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PCSK1 ADCY4 ACACB FBXL8 NEU3 EGR3 HECW2 PLXNB1	5.43e-08	179	129	8	9863ab3ceb160a4b1d9790033a4ac48845863d65
ToppCell	droplet-Fat-Bat-18m-Endothelial\|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PCSK1 ADCY4 ACACB FBXL8 NEU3 EGR3 HECW2 PLXNB1	5.43e-08	179	129	8	dfe110add7228cd834b35916cbcc849769a01bb9
ToppCell	droplet-Kidney-KIDNEY-1m-Epithelial-Pecam____fenestrated_capillary_endothelial\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	AKT3 WNT2 ABCC9 LAMC3 KLHL11 PXDN HECW2 NOTCH3	5.67e-08	180	129	8	79c5725f02e038d0187f4a1e1591f2492538aa57
ToppCell	wk_15-18-Hematologic-Myeloid-aDC_1\|wk_15-18 / Celltypes from embryonic and fetal-stage human lung	DOCK10 FOXD4L6 FOXD4L5 MELTF FOXD4L4 FOXD4L3 FOXD4	8.64e-07	177	129	7	ccf5dc54780d6039a4d062dee88440c011ddc0a3
ToppCell	COPD-Stromal-Pericyte\|COPD / Disease state, Lineage and Cell class	COL3A1 CACNA1C ABCC9 LAMC3 PXDN PRICKLE2 NOTCH3	1.12e-06	184	129	7	a56264a22dfc2d3672b20134ab7c3c7c23da5ae1
ToppCell	droplet-Heart-nan-24m-Mesenchymal-cardiomyocyte\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GPC1 CACNA1C MYOM1 KCNG2 TNNI3K PDE4DIP MTUS2	1.49e-06	192	129	7	f6a4e348406a852ace9fb21db8fbdff539217645
ToppCell	droplet-Heart-nan-24m-Mesenchymal-atrial_cardiomyocyte\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GPC1 CACNA1C MYOM1 KCNG2 TNNI3K PDE4DIP MTUS2	1.49e-06	192	129	7	1a0c25106ae08eac912a4edd5fc1a3ee776f69c2
ToppCell	10x_3'_v2v3-Non-neoplastic-Vascular-Mural_cell-Pericyte-C\|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	COL3A1 ADCY4 ABCC9 LAMC3 PXDN HECW2 NOTCH3	1.71e-06	196	129	7	12d9028f90c057c6e5cff00301793fa550e86c5a
ToppCell	PCW_13-14-Mesenchymal\|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung	COL3A1 CACNA1C ENPP2 WNT2 DOCK10 SRGAP3 PRICKLE2	1.77e-06	197	129	7	73a2085d2682d636726a5432d572ae2a3fbe1c3f
ToppCell	PND03-Immune-Immune_Myeloid-DC-cDC1-cDC1_prolif\|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	TRNP1 ACACB ZNF689 DOCK10 EVC SRGAP3	6.31e-06	156	129	6	af47a4b17342bdb3cb62d7e2d52a81168e588629
ToppCell	Hippocampus-Neuronal-Excitatory-eN1(Slc17a7)\|Hippocampus / BrainAtlas - Mouse McCarroll V32	NPR3 WNT2 KCNG2 EGR3 EGR4 PRICKLE2	9.65e-06	168	129	6	6db453cbbbaf4144a86fadcfa5805d33396713b5
ToppCell	droplet-Trachea-3m-Endothelial-endothelial_cell_of_trachea-tracheal_endothelial_cell-tracheal_endothelial_cell_28\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	NPR3 ACACB PASK HECW2 FHOD1 CCDC78	1.14e-05	173	129	6	66488d01e03264fb193285470901c9c4182fbae8
ToppCell	droplet-Thymus-nan-24m-Lymphocytic-thymocyte\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CDKN3 NEU3 B3GNT3 SLX4 NOTCH1 NOTCH3	1.52e-05	182	129	6	39f9b3eb22293cc27c6e175702c77d1eeb24fdc9
ToppCell	droplet-Limb_Muscle-nan-21m-Mesenchymal-unknown\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PCSK1 MYOM1 ABCC9 GRIN2B ACTN3 NOTCH3	1.57e-05	183	129	6	6f5dbac2748f50105f0f548d189c42ef14287019
ToppCell	PCW_07-8.5-Mesenchymal-Mesenchymal_fibroblastic-mes_immature3_(17)\|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung	COL3A1 ENPP2 WNT2 EXT1 SRGAP3 PRICKLE2	1.77e-05	187	129	6	a9316e2818217ec5feae9cf8816f7249803caee6
ToppCell	RV-06._Ventricular_Cardiomyocyte_II\|World / Chamber and Cluster_Paper	CACNA1C ERBB4 ACACB MYOM1 PDE4DIP MTUS2	1.88e-05	189	129	6	5e80c47f63980904c4c1ff02c201b67b456a0974
ToppCell	facs-Heart-RA-24m-Mesenchymal-ventricular_myocyte\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GPC1 ERBB4 MYOM1 KCNG2 TNNI3K MTUS2	1.88e-05	189	129	6	e758b264c0a47127e33e66c395cf5a3224c7305b
ToppCell	facs-Heart-RA-24m-Mesenchymal-ventricular_cardiomyocyte\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GPC1 ERBB4 MYOM1 KCNG2 TNNI3K MTUS2	1.88e-05	189	129	6	b98f60875b1a12b2ec9dc91889298ae57f98602f
ToppCell	LV-06._Ventricular_Cardiomyocyte_II\|World / Chamber and Cluster_Paper	CACNA1C ERBB4 ACACB MYOM1 PDE4DIP MTUS2	1.94e-05	190	129	6	de5ef606a002f85c2e0e3a36c1f259d0b85a76ff
ToppCell	RV-06._Ventricular_Cardiomyocyte_II\|RV / Chamber and Cluster_Paper	CACNA1C ERBB4 ACACB MYOM1 PDE4DIP MTUS2	1.94e-05	190	129	6	fe8e78922c8ae928ef9a80bffd67868d5a87a091
ToppCell	LV-06._Ventricular_Cardiomyocyte_II\|LV / Chamber and Cluster_Paper	CACNA1C ERBB4 ACACB MYOM1 PDE4DIP MTUS2	2.00e-05	191	129	6	25f3eb34f4e70761e81e84c8a5829f216108cbc6
ToppCell	droplet-Heart-4Chambers-21m-Mesenchymal-cardiomyocyte\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GPC1 MYOM1 KCNG2 TNNI3K PDE4DIP MTUS2	2.00e-05	191	129	6	c172c9e17b893b290e4aa8af5e5e4cd3e4818372
ToppCell	human_hepatoblastoma-Hepatic_Stellate_cells\|human_hepatoblastoma / Sample and Cell Type and Tumor Cluster (all cells)	COL3A1 CACNA1C AKT3 ABCC9 LAMC3 NOTCH3	2.00e-05	191	129	6	78c3c2fdb68c3407f2436f90e1e6a780bbf8b79e
ToppCell	droplet-Heart-nan-3m-Mesenchymal-atrial_cardiomyocyte\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GPC1 MYOM1 KCNG2 TNNI3K PDE4DIP MTUS2	2.00e-05	191	129	6	97fb4232417a39801e87725755fd16a57c250209
ToppCell	droplet-Heart-nan-3m-Mesenchymal-cardiomyocyte\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GPC1 MYOM1 KCNG2 TNNI3K PDE4DIP MTUS2	2.00e-05	191	129	6	64070a309d7e3f6001272409ab9ce206d0e7d73f
ToppCell	droplet-Heart-4Chambers-21m-Mesenchymal-atrial_cardiomyocyte\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GPC1 MYOM1 KCNG2 TNNI3K PDE4DIP MTUS2	2.00e-05	191	129	6	715f5b449b8e075959c05a5b38389df319663164
ToppCell	droplet-Heart-nan-18m-Mesenchymal-cardiomyocyte\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GPC1 MYOM1 KCNG2 TNNI3K PDE4DIP MTUS2	2.06e-05	192	129	6	0bf99e029a06151092db1e8a0dcb45f4e688e771
ToppCell	facs-Lung-nan-3m-Endothelial-Capillary_endothelial_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ADCY4 NPR3 PXDN HECW2 PRICKLE2 NOTCH1	2.06e-05	192	129	6	4bab9754cfd8b9c2d7cc1490e8a29f58c3c26f6c
ToppCell	droplet-Lung-18m-Mesenchymal-myofibroblast\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	COL3A1 MYOM1 ENPP2 ZNF365 ITIH4 NOTCH3	2.06e-05	192	129	6	2cc712186e37fb21a964c032765c36a8b4a852cf
ToppCell	droplet-Heart-nan-18m-Mesenchymal-atrial_cardiomyocyte\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GPC1 MYOM1 KCNG2 TNNI3K PDE4DIP MTUS2	2.06e-05	192	129	6	d766221acfce30cbf2c60b3ae40f6744968b952c
ToppCell	PCW_13-14-Mesenchymal-Mesenchymal_fibroblastic-mes_immature5_(6)\|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung	COL3A1 ENPP2 WNT2 DOCK10 SRGAP3 PRICKLE2	2.18e-05	194	129	6	b1bb0f846d2865efdd9bc8842b16b9d069785882
ToppCell	facs-Lung-nan-3m-Endothelial-endothelial_cell_of_lung\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ADCY4 NPR3 PXDN HECW2 PRICKLE2 NOTCH1	2.18e-05	194	129	6	f159ef8541d75a4e98468947f231bb463bec922c
ToppCell	RA-03._Atrial_Cardiomyocyte\|RA / Chamber and Cluster_Paper	CACNA1C ERBB4 ACACB MYOM1 PDE4DIP MTUS2	2.18e-05	194	129	6	c3535f7cc0076653c72db582047cff053c322397
ToppCell	droplet-Bladder-Unstain-18m-Endothelial\|Bladder / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ADCY4 MYOM1 ABCC9 LAMC3 HECW2 NOTCH3	2.24e-05	195	129	6	fbfe4a8ae9775764108b45920eec92003b24fb2e
ToppCell	PCW_10-12-Mesenchymal-Mesenchymal_fibroblastic-mes_immature5_(6)\|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung	COL3A1 ENPP2 WNT2 DOCK10 SRGAP3 PRICKLE2	2.24e-05	195	129	6	0e55fa5b3cbeb7baee3d4ac272a3bf80381ec937
ToppCell	droplet-Bladder-Unstain-18m-Endothelial-endothelial_cell\|Bladder / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ADCY4 MYOM1 ABCC9 LAMC3 HECW2 NOTCH3	2.24e-05	195	129	6	2a6056172c41c46acfe0242be22269ef1d07921e
ToppCell	droplet-Heart-HEART-1m-Mesenchymal-cardiomyocyte\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GPC1 MYOM1 KCNG2 TNNI3K PDE4DIP MTUS2	2.31e-05	196	129	6	a582130862bee76c0385156a333bfdfc75cf218b
ToppCell	droplet-Heart-HEART-1m-Mesenchymal-atrial_cardiomyocyte\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GPC1 MYOM1 KCNG2 TNNI3K PDE4DIP MTUS2	2.31e-05	196	129	6	fba52a4b82086dbae9a55038bf44c4539be926f5
ToppCell	10x_3'_v2v3-Non-neoplastic-Vascular-Mural_cell-Pericyte-G\|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	COL3A1 ADCY4 ABCC9 LAMC3 PXDN NOTCH3	2.31e-05	196	129	6	73f029d2b276776d6c24356b14c6592c9cb74bd5
ToppCell	PCW_10-12-Mesenchymal-Mesenchymal_fibroblastic\|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung	COL3A1 CACNA1C ENPP2 WNT2 SRGAP3 PRICKLE2	2.44e-05	198	129	6	17dc055e2a289496d9c5cdbf3297bdf906dc6d22
ToppCell	Brain_organoid-organoid_Kanton_Nature-Organoid-2M-Neuronal\|Organoid-2M / Sample Type, Dataset, Time_group, and Cell type.	CDKN2D GRIN2B DCX PDE4DIP SYT13 DMTN	2.51e-05	199	129	6	5de2a32bc2e9c752eb19a013b1807949153728fc
ToppCell	Brain_organoid-organoid_Kanton_Nature-Organoid-4M-Neuronal\|Organoid-4M / Sample Type, Dataset, Time_group, and Cell type.	CDKN2D ERBB4 MYCBP2 DCX PDE4DIP DMTN	2.51e-05	199	129	6	77b4aa00f14b86ef5db0490be98787e063979541
ToppCell	Fetal_brain-fetalBrain_Zhong_nature-GW26-Neuronal-GABAergic_neurons\|GW26 / Sample Type, Dataset, Time_group, and Cell type.	CACNA1C ERBB4 MYCBP2 DCX PDE4DIP SYT13	2.59e-05	200	129	6	bad32a95b759fad509401b07bc96a56687c2a592
ToppCell	droplet-Heart-HEART_(ALL_4:4:4:1:1)-30m-Endothelial\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CDKN3 ADCY4 SBNO1 RGL2 NOTCH1	3.32e-05	126	129	5	4eeea015efe17e0aae5bd76b71fa70b5149dfada
ToppCell	TCGA-Endometrium-Primary_Tumor-Endometrial_Adenocarcinoma-Endometrioid-7\|TCGA-Endometrium / Sample_Type by Project: Shred V9	CACNA1C AKT3 ADCY4 ENPP2 ABCC9	6.48e-05	145	129	5	ffbdadea0185e5d3b85f2868d5ec82b50cf2e2a1
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell-Peritubular_Capilary_Endothelial_Cell__prolif\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	ADCY4 WNT2 WNT8A HECW2 HELZ2	8.88e-05	155	129	5	59035d792c26d870a8b097939e97fa47859ba68c
ToppCell	Children_(3_yrs)-Epithelial-basal_cell-D032\|Children_(3_yrs) / Lineage, Cell type, age group and donor	ERBB4 MELTF SRGAP3 PRICKLE2 PLXNB1	9.43e-05	157	129	5	6ee2692f705bdd93ba523dffaf2f0cd921b47e28
ToppCell	TCGA-Bladder-Primary_Tumor-Urothelial_Carcinoma-Papillary_Muscle_Invasive_Urothelial_Carcinoma\|TCGA-Bladder / Sample_Type by Project: Shred V9	SH2B1 SAMD10 MZF1 RGL2 PLXNB1	9.72e-05	158	129	5	dc559503bab3ec1b9ea54ef2e896d1be33e5344c
ToppCell	facs-Lung-24m-Endothelial-capillary_endothelial-capillary_endothelial_cell-capillary_type_1_endothelial_cell\|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	PCSK1 CACNA1C ERBB4 USP29 GRIN2B	1.09e-04	162	129	5	bf886e22ff2a20353499004b53f25fb9e6574896
ToppCell	Fetal_brain-fetalBrain_Zhong_nature-GW16-Neuronal-GABAergic_neurons\|GW16 / Sample Type, Dataset, Time_group, and Cell type.	ERBB4 MYCBP2 DCX QRICH2 PDE4DIP	1.16e-04	164	129	5	4d7b2d0980fb4f47721fa2891151e2bd892ccb91
ToppCell	Fetal_brain-fetalBrain_Zhong_nature-GW19-Neuronal-GABAergic_neurons\|GW19 / Sample Type, Dataset, Time_group, and Cell type.	CACNA1C ERBB4 DCX PDE4DIP	1.25e-04	88	129	4	5582fd7bac60c690ecd1f2aff1d446ccb69f79b9
ToppCell	367C-Lymphocytic-NK_cells-NK_cell_E\|NK_cells / Donor, Lineage, Cell class and subclass (all cells)	MYOM1 ZNF365 EGR4 SRGAP3 DMTN	1.26e-04	167	129	5	b5d15773be32cd277125fd3b4056a8fefaefa5ec
ToppCell	Healthy_donor-HSPC\|World / disease group, cell group and cell class (v2)	CACNA1C NPR3 TNNI3K PLXNB1 NOTCH3	1.26e-04	167	129	5	70630ebdfee8171d625811844f8a7c94736d101e
ToppCell	Adult-Mesenchymal-vascular_smooth_muscle_cell-D175\|Adult / Lineage, Cell type, age group and donor	CACNA1C PXDN EGR3 MTUS2 NOTCH3	1.26e-04	167	129	5	c4e321bb87512ea839f324c92c0f1afea891483f
ToppCell	P28-Epithelial-airway_epithelial_cell-ciliated_cell_of_airway\|P28 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	GPC1 FBXL8 SH2B1 STAT5B TNRC18	1.30e-04	168	129	5	8c8dbdbc7053f34e4ca0c5067af502fbea109fc1
ToppCell	E18.5-Mesenchymal-Mesenchymal_structural-Fibroblastic-PMP-PMP_mature\|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	COL3A1 GPC1 CDKN3 ABCC9 QRICH2	1.33e-04	169	129	5	7cb1b87be66a22fe5731bb1b55bc515920fe3e8b
ToppCell	10x_3'_v2v3-Non-neoplastic-Vascular-Mural_cell-Pericyte-B\|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	COL3A1 EVC ABCC9 LAMC3 NOTCH3	1.41e-04	171	129	5	a4a2c5dc995589fbe3d4ca6ee1df888807e4ae34
ToppCell	Healthy_donor-HSPC\|Healthy_donor / disease group, cell group and cell class (v2)	CACNA1C NPR3 TNNI3K PLXNB1 NOTCH3	1.45e-04	172	129	5	bc7549faadfc92c683c0e26bea380458706774b5
ToppCell	facs-Pancreas-Exocrine-3m-Epithelial-pancreatic_B_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CACNA1C HUS1B KLHL11 GRID2IP PDE4DIP	1.53e-04	174	129	5	f1fe1f4216748a9562dd03bd48c70b23c7ff4d1d
ToppCell	facs-Lung-24m-Mesenchymal-myofibroblast-myofibroblast_cell\|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	DUSP12 ENPP2 ABCC9 SH2B1 CREG2	1.53e-04	174	129	5	eb8012823b08729b462d1e5212f4873bb6b4eb1e
ToppCell	facs-Lung-24m-Mesenchymal-myofibroblast-myofibroblast_cell-pulmonary_interstitial_myofibroblast\|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	DUSP12 ENPP2 ABCC9 SH2B1 CREG2	1.53e-04	174	129	5	32fdeeebeeeca657eac6329caad4c28ca54e4d1c
ToppCell	3'-Child04-06-SmallIntestine-Epithelial-neuro-epithelial-EC_cells_(TAC1+)\|Child04-06 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	PCSK1 PRODH2 SCT MTUS2 SYT13	1.53e-04	174	129	5	a62531ebf16b32b249168dca11b870f63a8aa81c
ToppCell	E16.5-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_vascular-Pericyte-Pericyte_G2M\|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	CDKN2D CDKN3 CFAP91 ABCC9 NOTCH3	1.57e-04	175	129	5	fa16c6ba08dc0cc22e8cf049db0577811d080df6
ToppCell	E18.5-Mesenchymal-Mesenchymal_structural-Fibroblastic-PMP\|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	COL3A1 CDKN2D CDKN3 QRICH2 SCT	1.57e-04	175	129	5	a154b28b0b2180652d51d4c7d804b3b81b35899e
ToppCell	facs-Trachea-24m-Mesenchymal-myofibroblast-tracheobronchial_smooth_muscle_cell\|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	GPC1 ITIH4 MELTF EGR4 PLXNB1	1.57e-04	175	129	5	f1394aacc8a94ca555dd19aaed5a18da99c6bf40
ToppCell	facs-Trachea-24m-Mesenchymal-myofibroblast\|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	GPC1 ITIH4 MELTF EGR4 PLXNB1	1.57e-04	175	129	5	7bf1194d93fbe2dbf9d953e0a32b2a6d88251ed1
ToppCell	3'-Adult-LargeIntestine-Endothelial-lymphatic_endothelial-LEC3_(ADGRG3+)\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	GRIN2B PXDN HECW2 RGL2 DMTN	1.61e-04	176	129	5	5d3b2395bb842eea39175f5af6a4c76527e2fc31
ToppCell	E16.5-Mesenchymal-Mesenchymal_structural-Fibroblastic-AF2-AF2_prolif\|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	COL3A1 TOR4A SRGAP3 HELZ2 PPP6R2	1.65e-04	177	129	5	30f82b04e48940bfcaf2c22677efe6d57ae3f1a7
ToppCell	390C-Endothelial_cells-Endothelial-E-\|390C / Donor, Lineage, Cell class and subclass (all cells)	ADCY4 NPR3 PXDN HECW2 SCT	1.70e-04	178	129	5	804ac3725c1f88e2212172bfb9aa01d97a735621
ToppCell	Fetal_29-31_weeks-Mesenchymal-vascular_smooth_muscle_cell-D150\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	CACNA1C NPR3 ABCC9 MTUS2 NOTCH3	1.70e-04	178	129	5	066dbc4cc2083c549d98122ed44707127f34d582
ToppCell	facs-Pancreas-Exocrine-3m-Epithelial-pancreatic_B_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PCSK1 CACNA1C HUS1B PDE4DIP SYT13	1.70e-04	178	129	5	fcbbcc44271515de1969b4732b6441c012693d5f
ToppCell	390C-Endothelial_cells-Endothelial-E\|390C / Donor, Lineage, Cell class and subclass (all cells)	ADCY4 NPR3 PXDN HECW2 SCT	1.70e-04	178	129	5	ad6dc4a375664c919bd48c35c48a561fc5a7de8c
ToppCell	3'-Adult-LargeIntestine-Epithelial-neuro-epithelial\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	PCSK1 TRNP1 EGR3 EGR4 SCT	1.74e-04	179	129	5	f93e81a3fd94adedb24a9db4ac1d53e275bbf8b5
ToppCell	Somatosensory_Cortex_(S1)-Non-neuronal-Mesenchymal-Mes\|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	COL3A1 ADCY4 LAMC3 HELZ2 NOTCH3	1.74e-04	179	129	5	368f7e91e9c2c854c8778788cead022d158d1122
ToppCell	3'-GW_trimst-1-SmallIntestine-Epithelial-neuro-epithelial-EC_cells_(TAC1+)\|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	PCSK1 ACTN3 PRODH2 SCT SYT13	1.74e-04	179	129	5	ec7c38464863ac3744a8d4880f49421914892339
ToppCell	facs-Brain_Non-Myeloid-Hippocampus-24m-Mesenchymal-brain_pericyte\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	NEU3 ABCC9 LAMC3 FHOD1 GAN	1.74e-04	179	129	5	f99500c4a590e5152ded5862690f7fa614d64a80
ToppCell	3'-Adult-LargeIntestine-Epithelial-neuro-epithelial-EC_cells_(TAC1+)\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	PCSK1 TRNP1 EGR3 EGR4 SCT	1.74e-04	179	129	5	878b15ea62e3405682a538f79f58d74b9cd3f398
ToppCell	facs-Brain_Non-Myeloid-Hippocampus-24m-Mesenchymal-Pericyte\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	NEU3 ABCC9 LAMC3 FHOD1 GAN	1.74e-04	179	129	5	7d61466181ab73088de3ec8a129d7cfa8cac7ecc
ToppCell	Somatosensory_Cortex_(S1)-Non-neuronal-Mesenchymal\|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	COL3A1 ADCY4 LAMC3 HELZ2 NOTCH3	1.74e-04	179	129	5	11e434fc49bc0a806197f21debcac8337e0502aa
ToppCell	facs-Brain_Non-Myeloid-Hippocampus-24m-Mesenchymal\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	NEU3 ABCC9 LAMC3 FHOD1 GAN	1.74e-04	179	129	5	6c98ce32cb55cf9cee557449e41b23bdb22f5efd
ToppCell	IPF-Myeloid-pDC\|Myeloid / Disease state, Lineage and Cell class	CXCR3 KCNG2 KAT2B PXDN SCT	1.79e-04	180	129	5	0f8567aa835d4e3a52f6631ae15216eca18a030c
ToppCell	5'-Adult-SmallIntestine-Mesenchymal-fibroblastic-Stromal_1_(ADAMDEC1+)\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	COL3A1 GPC1 PXDN PRICKLE2 SCT	1.79e-04	180	129	5	f2f6e83127a4a415e65c76a35efa8175fbd5b5d9
ToppCell	Smart-start-Cell-Wel_seq-Non-neoplastic-Vascular-Mural_cell-SMC_prolif\|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	COL3A1 ABCC9 LAMC3 HECW2 NOTCH3	1.79e-04	180	129	5	64956a85c404a2ea7e4eaf6f95ebcc52c198b7cc
ToppCell	Fetal_29-31_weeks-Endothelial-alveolar_capillary_endothelial_cell_(Cap2;_aerocyte)-D088\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	FOXR1 PXDN HECW2 HELZ2 PRICKLE2	1.79e-04	180	129	5	d8ef44710a77ad0fc03243428e5e1dc4d41200cb
ToppCell	5'-GW_trimst-2-SmallIntestine-Epithelial-neuro-epithelial-EC_cells_(TAC1+)\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	PCSK1 TRNP1 PRODH2 SCT SYT13	1.79e-04	180	129	5	6b1606238417490e0d9930870a7827419d1c3737
ToppCell	Mid-temporal_gyrus_(MTG)-Neuronal-Inh_GABAergic-i_Gaba_2-GABA_VIP_2-Inh_L2-5_VIP_TOX2\|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	ERBB4 NPR3 DOCK10 LAMC3 KCNG2	1.83e-04	181	129	5	35bcdcd2651149692e5b150e887c0f450c81d2d4
ToppCell	Somatosensory_Cortex_(S1)-Neuronal-Inh_GABAergic-i_Gaba_2\|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	ERBB4 NPR3 DOCK10 LAMC3 KCNG2	1.88e-04	182	129	5	420a8fd30543e37a66ba0786215d056d308660d0
ToppCell	primary_auditory_cortex_(A1C)-Neuronal-Inh_GABAergic-i_Gaba_2-GABA_VIP_2-Inh_L1-3_VIP_ZNF322P1\|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	ERBB4 NPR3 DOCK10 NLRP6 PXDN	1.88e-04	182	129	5	d3a037268f026eb2f84428b1821022503cef7756
ToppCell	Somatosensory_Cortex_(S1)-Non-neuronal-Mesenchymal-Mes-Pericyte-Peri_L1-6_MUSTN1\|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	ADCY4 ABCC9 LAMC3 HELZ2 NOTCH3	1.93e-04	183	129	5	944f7458b9127356815f75c88bbf7015ebdc8ec1
ToppCell	tumor_Lung-Fibroblasts-Pericytes\|tumor_Lung / Location, Cell class and cell subclass	COL3A1 CACNA1C ABCC9 LAMC3 NOTCH3	1.93e-04	183	129	5	a03dd563af9b15cb1f5de5732a229405a9f82d84
ToppCell	renal_medulla_nuclei-CKD+DKD_normotensive-Mesenchymal-Myocytic_interstitial_cell\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	COL3A1 MYOM1 ABCC9 LAMC3 NOTCH3	1.93e-04	183	129	5	667717366cb181b8a04a347e64f0f5a4dfc6ee7f
ToppCell	Somatosensory_Cortex_(S1)-Non-neuronal-Mesenchymal-Mes-Pericyte\|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	ADCY4 ABCC9 LAMC3 HELZ2 NOTCH3	1.93e-04	183	129	5	cee6b821adff538078232689965d3e6c131e7d14
ToppCell	Somatosensory_Cortex_(S1)-Neuronal-Inh_GABAergic-i_Gaba_2-GABA_VIP_2\|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	ERBB4 NPR3 DOCK10 LAMC3 KCNG2	1.98e-04	184	129	5	32473dbdb2de66391157c5814ef34e790806e4f2
ToppCell	LPS-IL1RA-Stromal_mesenchymal-Lung_smooth_muscle-Pericyte_2\|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	COL3A1 CACNA1C ABCC9 LAMC3 NOTCH3	1.98e-04	184	129	5	102b6f621a5b551e622f97b12d787c080b052a72
ToppCell	LV-15._Ventricular_Cardiomyocyte_III\|LV / Chamber and Cluster_Paper	CACNA1C ACACB MYOM1 GOLGA6B PDE4DIP	1.98e-04	184	129	5	ab7a1620c14a9d9b6be1b47c559931e345e9eef8
ToppCell	droplet-Kidney-KIDNEY-1m-Epithelial-Pecam____kidney_capillary_endothelial_cell\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	NPR3 QRICH2 KCNG2 PXDN PRICKLE2	1.98e-04	184	129	5	1c857126c0ea0671f0d60b048efca288d348d653
ToppCell	droplet-Lung-21m-Mesenchymal-fibroblast-adventitial_fibroblast-adventitial_fibroblast_l17\|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	COL3A1 TRNP1 EVC ABCC9 ZNF365	2.03e-04	185	129	5	1b990e3089772be2b38c6d7ea0d1bf22461ae3ea
ToppCell	facs-Skin-nan-24m-Mesenchymal\|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	COL3A1 ENPP2 ABCC9 LAMC3 SRGAP3	2.03e-04	185	129	5	8433a337625ff8398520e223ef92bf9bb0beb14c
ToppCell	facs-Skin-nan-24m-Mesenchymal-fibroblast\|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	COL3A1 ENPP2 ABCC9 LAMC3 SRGAP3	2.03e-04	185	129	5	049d793d043d5d434f143025de49dd210d18756c
Drug	Bethanechol chloride [590-63-6]; Down 200; 20.4uM; MCF7; HT_HG-U133A	GPC1 ATP9B B3GNT3 ZNF442 XAB2 STAT5B MZF1 PRR14L PLXNB1 NOTCH3	1.84e-07	198	128	10	3537_DN
Disease	Splenomegaly	APC STAT5B NOTCH1	9.31e-05	22	119	3	C0038002
Disease	Autistic Disorder	CACNA1C WNT2 APC EXT1 GRIN2B PASK SCT	9.43e-05	261	119	7	C0004352
Disease	age at menarche	PCSK1 SEMA6C AKT3 ERBB4 INO80 REXO1 NLRP6 TNNI3K GAN SLX4	1.51e-04	594	119	10	EFO_0004703
Disease	Turcot syndrome (disorder)	PMS2 APC	1.60e-04	5	119	2	C0265325
Disease	colorectal cancer (implicated_via_orthology)	APC NOTCH1 NOTCH3	2.40e-04	30	119	3	DOID:9256 (implicated_via_orthology)
Disease	intestinal cancer (implicated_via_orthology)	ERBB4 NOTCH1 NOTCH3	2.91e-04	32	119	3	DOID:10155 (implicated_via_orthology)
Disease	adenocarcinoma (implicated_via_orthology)	NOTCH1 NOTCH3	3.34e-04	7	119	2	DOID:299 (implicated_via_orthology)
Disease	central nervous system cancer (implicated_via_orthology)	NOTCH1 NOTCH3	3.34e-04	7	119	2	DOID:3620 (implicated_via_orthology)
Disease	Lynch Syndrome	PMS2 APC	5.70e-04	9	119	2	C4552100
Disease	Combined immunodeficiency	STAT5A STAT5B RECQL4	6.10e-04	41	119	3	C0494261
Disease	Adenocarcinoma of large intestine	ERBB4 PMS2 APC TNNI3K	6.28e-04	96	119	4	C1319315
Disease	Shortened QT interval	CACNA1C ABCC9	8.66e-04	11	119	2	C0151879
Disease	Schizophrenia	COL3A1 CACNA1C ERBB4 APC GRIN2B PRODH2 SBNO1 EGR3 EGR4 SRGAP3 HSPA9	9.08e-04	883	119	11	C0036341
Disease	Dupuytren Contracture	ADCY4 WNT2 PXDN SRGAP3	9.76e-04	108	119	4	EFO_0004229
Disease	ovarian reserve	NPR3 GRIN2B	1.04e-03	12	119	2	EFO_0004770
Disease	Glioblastoma Multiforme	AKT3 APC NOTCH1 NOTCH3	1.08e-03	111	119	4	C1621958
Disease	Polydactyly	AKT3 EVC PNPLA6 MEGF8	1.31e-03	117	119	4	C0152427
Disease	Impaired cognition	CACNA1C NOTCH3	1.42e-03	14	119	2	C0338656
Disease	schizophrenia (biomarker_via_orthology)	ERBB4 GRIN2B	1.64e-03	15	119	2	DOID:5419 (biomarker_via_orthology)
Disease	amino acid measurement	ERBB4 ACACB GRIN2B PASK PXDN SUN2 GAN MTUS2 NOTCH1	1.74e-03	678	119	9	EFO_0005134
Disease	Malignant neoplasm of skin	ERBB4 NOTCH1 NOTCH3	1.76e-03	59	119	3	C0007114
Disease	Skin Neoplasms	ERBB4 NOTCH1 NOTCH3	1.76e-03	59	119	3	C0037286
Disease	Polyposis, Adenomatous Intestinal	APC ITIH4	1.87e-03	16	119	2	C2713442
Disease	Familial Intestinal Polyposis	APC ITIH4	1.87e-03	16	119	2	C2713443
Disease	Cerebrovascular accident	COL3A1 CXCR3 NOTCH3	2.03e-03	62	119	3	C0038454
Disease	sex interaction measurement, ulcerative colitis	ZNF365 SH2B1	2.11e-03	17	119	2	EFO_0000729, EFO_0008343
Disease	Adenomatous Polyposis Coli	APC ITIH4	2.11e-03	17	119	2	C0032580
Disease	schizophrenia (implicated_via_orthology)	AKT3 SBNO1 SRGAP3	2.65e-03	68	119	3	DOID:5419 (implicated_via_orthology)
Disease	alkaline phosphatase measurement	ACACB ZNF689 WDR81 EVC ITIH4 SAMD10 UCKL1 RECQL4 PRR14L PPP6R2 NOTCH1	2.72e-03	1015	119	11	EFO_0004533
Disease	rheumatoid arthritis (is_marker_for)	CXCR3 KAT2B HSPA9	2.76e-03	69	119	3	DOID:7148 (is_marker_for)
Disease	pulse pressure measurement, alcohol drinking	NPR3 ERCC6 ENPP2	2.88e-03	70	119	3	EFO_0004329, EFO_0005763
Disease	temporal lobe epilepsy (is_marker_for)	GRIN2B DCX	2.92e-03	20	119	2	DOID:3328 (is_marker_for)
Disease	seborrheic dermatitis	TNRC18 PRICKLE2	2.92e-03	20	119	2	EFO_1000764
Disease	type 2 diabetes mellitus (biomarker_via_orthology)	COL3A1 PCSK1 CYP11A1 DCX	3.01e-03	147	119	4	DOID:9352 (biomarker_via_orthology)
Disease	Endometrial Carcinoma	PMS2 CYP11A1 ABCC9	3.11e-03	72	119	3	C0476089
Disease	hyperglycemia (biomarker_via_orthology)	PCSK1 CYP11A1	3.22e-03	21	119	2	DOID:4195 (biomarker_via_orthology)
Disease	pulse pressure measurement, alcohol consumption measurement	NPR3 ENPP2	3.53e-03	22	119	2	EFO_0005763, EFO_0007878
Disease	prostate cancer (is_marker_for)	ERBB4 PMS2 WNT2 STAT5A	3.73e-03	156	119	4	DOID:10283 (is_marker_for)

Protein segments in the cluster

Peptide	Gene	Start	Entry
LTLRTCDRFSRHSVA	SYT13	241	Q7L8C5
RRTALSSTDTFLLHL	CXCR3	81	P49682
TSIEHNRDLSFLRSV	ERBB4	66	Q15303
HRSFGTRLSRVRSLE	AGAP9	551	Q5VTM2
LERHRQTRSSTETFL	CXCR5	76	P32302
ERALRATFREALSSL	ADCY4	196	Q8NFM4
ATFREALSSLHSRRR	ADCY4	201	Q8NFM4
IVSDSRRESRHLHLF	ABCC9	91	O60706
AVVSFLAAESDLHRR	CDKN2D	121	P55273
RDANRSLDIFDERSH	CCNYL1	156	Q8N7R7
RLRAATARSLAHASV	CREG2	121	Q8IUH2
HLSRERVFSEDRTRF	AKT3	236	Q9Y243
HREALRQLTTTDASF	CFAP91	111	Q7Z4T9
HRELREDSIRSHFSV	NPR3	526	P17342
TFERLGRDAEAAHRA	PRODH2	356	Q9UF12
GLRLLLRDTDRFSSH	ITIH4	856	Q14624
ELRRHSLERASSSVA	MTUS2	171	Q5JR59
SLHTRTRSLDFREIG	RBSN	541	Q9H1K0
TFQFKSDSDRHRSRE	QRICH2	166	Q9H0J4
ERALRLDHFLRQTSA	INO80	26	Q9ULG1
TDHRFFIRAIIRHSD	ACACB	1536	O00763
RRDRFETIFSNLHVA	ERCC6	686	P0DP91
ADFRRENILPHSTSR	HECW2	896	Q9P2P5
VFSRRADRHSDFSRL	PNPLA6	956	Q8IY17
ADRHSDFSRLARVLT	PNPLA6	961	Q8IY17
DLLHSQRDSAARTRL	PASK	931	Q96RG2
RNSSFHFLRELSRVL	NOTCH1	1586	P46531
HTLRSFLSLFLDERD	DOLK	386	Q9UPQ8
SAHSARDEAARLEER	KAT2B	476	Q92831
SHAELETALRDSSRV	GPC1	81	P35052
RHREADASLSALRVL	FOXD4L4	316	Q8WXT5
RHREADASLSALRVL	FOXD4L3	316	Q6VB84
TSRGEAHLELNAFRR	ATP9B	796	O43861
HTLESQRTFSARDRA	PLXNB1	1621	O43157
HLAERELGARRDFSS	KCNG2	341	Q9UJ96
RENHLVSTFSSREDL	PNPLA4	121	P41247
HCSLRRSTDISTFRN	GHDC	81	Q8N2G8
SAILRTSLRFRLDAH	NOTCH3	1536	Q9UM47
DSRLSADTASRFLHR	MEGF8	1496	Q7Z7M0
RREADAALFSELHRK	TUBGCP3	66	Q96CW5
VRSFARSDELNRHLR	EGR4	491	Q05215
RRHREADASLSALRV	FOXD4	311	Q12950
EDRSSSCREAVLHRR	GOLGA6B	186	A6NDN3
NGLSHEAFRLVSRRD	HSPA9	31	P38646
LREVRDSHFFSIITD	THAP12	251	O43422
RRSRSDNALHLASER	PRICKLE2	691	Q7Z3G6
SHPVRSRDTDRFLDV	GRID2IP	671	A4D2P6
REFRAHRSVLAAATE	KLHL11	106	Q9NVR0
SHFRSLSDAVQRLLS	BICRAL	721	Q6AI39
LRSASLGRRASFHLE	CACNA1C	1971	Q13936
LEETRRANHSVARFL	DOCK10	1046	Q96BY6
LQFRASRSHSRREEH	EXT1	26	Q16394
ETDHLFDLSRRFDLR	DMAP1	156	Q9NPF5
IFRHLSLRDRAAAAR	FBXL8	16	Q96CD0
FSRSDELTRHLRIHT	EGR3	286	Q06889
QHAARLLRALSSFRE	GAN	11	Q9H2C0
RFRSFDALLADLTRS	DCX	76	O43602
EGHRRFAEEARALAS	FOXR1	256	Q6PIV2
RTFLEATLEDIRAAH	CCDC78	271	A2IDD5
LDAVSRDFVSVLHRR	CYP11A1	171	P05108
SRFTAAALRRAAHVL	B3GNT3	276	Q9Y2A9
ELTAEHLSRAARSAA	HUS1B	81	Q8NHY5
DVHLAFLRLLSSRAS	COL3A1	1351	P02461
FSDLRELFARRLASH	EXOC1	336	Q9NV70
ATSDDRFLSRTFLRV	EVC	181	P57679
SVDTARLEHLFESRA	FHOD1	661	Q9Y613
GLERLTAEARHSRLF	HELZ2	1251	Q9BYK8
EFRDKLAAHLSSRDS	CDKN3	191	Q16667
RLERHLSAEDFSRVF	DMTN	366	Q08495
RSLFRSSSILDHREG	DUSP12	226	Q9UNI6
RRHSDGTFTSELSRL	SCT	26	P09683
HGDRRATESRDLSRF	SBNO1	1021	A3KN83
LARARRTESFHSYRD	KCTD3	656	Q9Y597
ARDFTVLVDRAIHSR	PEX1	781	O43933
RVRDIEHLTSLDFFR	ENPP2	826	Q13822
RSDTHTFNRLFRRDE	NLRP6	176	P59044
AAILSHAAREERTEA	PPP6R2	396	O75170
DSRSTLSRRELDAAH	PRR14L	1091	Q5THK1
SFASAAELAEHREVR	MIGA1	326	Q8NAN2
ERRRLDSALLALSSH	RUNDC1	86	Q96C34
SARHLSRASSRDERA	REXO1	241	Q8N1G1
HDFLLRQRRRSSTAT	RGL2	726	O15211
ESHARAAALDFARRF	SH2B1	31	Q9NRF2
VTHTRRTFDRALRAL	XAB2	126	Q9HCS7
VVRRDSSHAFTLDEL	MELTF	456	P08582
ASTRHRVLTSAFSRA	SCYL1	461	Q96KG9
RELRRHVHADSTDFL	RECQL4	826	O94761
RHREADASLSALRVL	FOXD4L5	316	Q5VV16
RHREADASLSALRVL	FOXD4L6	316	Q3SYB3
RRDVDATAHFSFCRT	SAMD10	26	Q9BYL1
FTTRDFSIRSLADRL	STAT5B	646	P51692
SLRRENELFSSHLVS	MYCBP2	1676	O75592
RVSSRRLLDFLDTHC	SLX4	1791	Q8IY92
FTTRDFSIRSLADRL	STAT5A	646	P42229
ALLRRHEAFESDLAA	ACTN3	446	Q08043
TDERNALRRSSAAHT	APC	916	P25054
HTFLAFAEKRSTRRD	NEU3	36	Q9UQ49
FAEKRSTRRDEDALH	NEU3	41	Q9UQ49
RRRSERIFLHDASAA	TNRC18	1996	O15417
DRDHSLFGRVLLRSS	WNT2	91	P09544
SSSLAEHRRLHAVAR	ZNF865	916	P0CJ78
RFRSLSSLRAHLEFS	ZNF365	36	Q70YC5
HSLERRLEALAAEFS	SUN2	281	Q9UH99
TRRESRDHATLNDIF	SRGAP3	106	O43295
SFFDVLDRHRESLLA	SPO11	11	Q9Y5K1
DRVATSRISDAHLAD	SPIN1	116	Q9Y657
DRAINSTRTHLFDSR	PXDN	636	Q92626
AFSRSSFLREHRRIH	ZNF696	301	Q9H7X3
SALESELVHFRDRAI	USP29	626	Q9HBJ7
RTLLVAARDHVFSFD	SEMA6C	71	Q9H3T2
SISRLREAFSLRHTT	PMS2	416	P54278
HFRERDSTRARLSPD	ZBTB42	316	B2RXF5
HIERRSSREDLRSAS	TOPAZ1	461	Q8N9V7
LLARHFRSVLEDSAL	TOR4A	206	Q9NXH8
AFRISSSLRRHETTH	ZNF442	441	Q9H7R0
RILFDDKRFADSTHR	YTHDC2	641	Q9H6S0
DCERRFSSSSRLVSH	ZNF689	321	Q96CS4
FAESSDLTRHRRIHT	ZNF165	381	P49910
EERELSVRAALASAH	UCKL1	301	Q9NWZ5
ISRLREAFSLRHTTE	PMS2CL	31	Q68D20
NRLRSATRETSFIHA	WNT8A	76	Q9H1J5
GRSHVAALRSRFELE	TNNI3K	756	Q59H18
EILSDRHAFETARRL	PPP1R10	436	Q96QC0
AAELRLAHRAESLSR	TRNP1	136	Q6NT89
LDVRTTLRNHVFFRD	USP6	146	P35125
AAHRALLESREVSRD	WDR81	526	Q562E7
ATEARALARSHRDTA	LAMC3	1156	Q9Y6N6
SAAHRRESEAFRRAS	MYOM1	51	P52179
SSDLSHLVAEVRALR	PDE4DIP	2041	Q5VU43
RESFARRAVLLEHQA	MZF1	491	P28698
RRESSVYDISEHRRS	GRIN2B	926	Q13224
RSAFHITKRLSDDDR	PCSK1	81	P29120