Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	cysteine-type deubiquitinase activity	USP17L21 USP13 USP17L4 USP17L2 USP17L23 USP17L12 USP17L1 USP17L20 USP17L11 USP17L24 USP17L5 USP17L10 USP17L19 USP17L18 USP17L17 USP17L6P USP17L3 USP17L22 USP17L15	1.00e-20	114	147	19	GO:0004843
GeneOntologyMolecularFunction	deubiquitinase activity	USP17L21 USP13 USP17L4 USP17L2 USP17L23 USP17L12 USP17L1 USP17L20 USP17L11 USP17L24 USP17L5 USP17L10 USP17L19 USP17L18 USP17L17 USP17L6P USP17L3 USP17L22 USP17L15	5.35e-20	124	147	19	GO:0101005
GeneOntologyMolecularFunction	ubiquitin-like protein peptidase activity	USP17L21 USP13 USP17L4 USP17L2 USP17L23 USP17L12 USP17L1 USP17L20 USP17L11 USP17L24 USP17L5 USP17L10 USP17L19 USP17L18 USP17L17 USP17L6P USP17L3 USP17L22 USP17L15	3.79e-19	137	147	19	GO:0019783
GeneOntologyMolecularFunction	cysteine-type peptidase activity	USP17L21 USP13 USP17L4 USP17L2 USP17L23 USP17L12 USP17L1 USP17L20 USP17L11 USP17L24 USP17L5 USP17L10 USP17L19 USP17L18 USP17L17 USP17L6P USP17L3 USP17L22 USP17L15	2.43e-16	192	147	19	GO:0008234
GeneOntologyMolecularFunction	peptidase activity	PRSS35 PCSK2 USP17L21 USP13 USP17L4 NAALADL1 USP17L2 USP17L23 USP17L12 USP17L1 USP17L20 USP17L11 USP17L24 USP17L5 USP17L10 USP17L19 USP17L18 USP17L17 USP17L6P USP17L3 USP17L22 USP17L15	2.68e-09	654	147	22	GO:0008233
GeneOntologyMolecularFunction	calcium ion binding	NAALADL1 FAT3 PCDHB14 SYT6 PON1 DGKG SYT2 PKD1L3 ZZEF1 HPCA EDEM3 EYS CANT1 HPCAL1 VCAN SYT5 PLCG1 ADGRE1	1.03e-05	749	147	18	GO:0005509
GeneOntologyMolecularFunction	lipid kinase activity	DGKG PIP5K1C PIK3C2A PIP5KL1	2.31e-04	41	147	4	GO:0001727
GeneOntologyMolecularFunction	transferase activity, transferring phosphorus-containing groups	RNGTT POLM DGKG SIRT6 PIP5K1C KSR1 LATS1 LATS2 PIK3C2A GUCY2C PIP5KL1 TJP2 PPIP5K1 PRKCG PRKD1 ADPGK CDK2	5.51e-04	938	147	17	GO:0016772
GeneOntologyMolecularFunction	phosphatidylinositol kinase activity	PIP5K1C PIK3C2A PIP5KL1	8.98e-04	26	147	3	GO:0052742
GeneOntologyMolecularFunction	N-acyltransferase activity	OGT BRCA2 BAZ1A MCM3AP ALAS2	9.49e-04	102	147	5	GO:0016410
GeneOntologyMolecularFunction	calcium-dependent phospholipid binding	SYT6 SYT2 SYT14 SYT5	9.98e-04	60	147	4	GO:0005544
GeneOntologyBiologicalProcess	protein deubiquitination	USP17L21 USP13 USP17L4 USP17L2 USP17L12 USP17L1 USP17L20 USP17L11 USP17L24 USP17L5 USP17L10 USP17L19 USP17L18 USP17L17 USP17L6P USP17L3 USP17L22 USP17L15	8.56e-19	125	146	18	GO:0016579
GeneOntologyBiologicalProcess	protein modification by small protein removal	USP17L21 USP13 USP17L4 USP17L2 USP17L12 USP17L1 USP17L20 USP17L11 USP17L24 USP17L5 USP17L10 USP17L19 USP17L18 USP17L17 USP17L6P USP17L3 USP17L22 USP17L15	1.17e-17	144	146	18	GO:0070646
GeneOntologyBiologicalProcess	post-translational protein modification	USP17L21 USP13 USP17L4 OGT USP17L2 USP17L12 USP17L1 USP17L20 USP17L11 USP17L24 USP17L5 USP17L10 USP17L19 BTBD1 SIRT6 ZZEF1 USP17L18 USP17L17 USP17L6P RNF38 USP17L3 PRKCG USP17L22 USP17L15 CDK2	1.38e-07	1074	146	25	GO:0043687
GeneOntologyBiologicalProcess	inner cell mass cell fate commitment	LATS1 LATS2 PRDM14	3.47e-07	3	146	3	GO:0001827
GeneOntologyBiologicalProcess	protein modification by small protein conjugation or removal	USP17L21 USP13 USP17L4 OGT USP17L2 USP17L12 USP17L1 USP17L20 USP17L11 USP17L24 USP17L5 USP17L10 USP17L19 BTBD1 ZZEF1 USP17L18 USP17L17 USP17L6P RNF38 USP17L3 PRKCG USP17L22 USP17L15	6.71e-07	1009	146	23	GO:0070647
GeneOntologyBiologicalProcess	inner cell mass cell differentiation	LATS1 LATS2 PRDM14	1.90e-05	8	146	3	GO:0001826
GeneOntologyBiologicalProcess	ribonucleoside diphosphate metabolic process	OGT GIT1 SIRT6 CANT1 RPTOR TJP2 ADPGK	7.22e-05	143	146	7	GO:0009185
GeneOntologyBiologicalProcess	nucleoside diphosphate metabolic process	OGT GIT1 SIRT6 CANT1 RPTOR TJP2 ADPGK	9.35e-05	149	146	7	GO:0009132
GeneOntologyBiologicalProcess	peptidyl-serine modification	OGT TFRC SMTNL1 LATS1 LATS2 RPTOR PRKCG PRKD1 MGAT5B CDK2	9.42e-05	319	146	10	GO:0018209
GeneOntologyBiologicalProcess	inner cell mass cellular morphogenesis	LATS1 LATS2	1.49e-04	3	146	2	GO:0001828
GeneOntologyBiologicalProcess	regulation of postsynaptic membrane neurotransmitter receptor levels	OGT GIT1 NBEA PIP5K1C TFRC HPCA PICK1	1.70e-04	164	146	7	GO:0099072
GeneOntologyBiologicalProcess	organophosphate catabolic process	OGT GIT1 PON1 SIRT6 CANT1 RPTOR UPP1 PLCG1 ADPGK	1.81e-04	281	146	9	GO:0046434
GeneOntologyBiologicalProcess	ribonucleoside diphosphate catabolic process	OGT GIT1 SIRT6 CANT1 RPTOR ADPGK	2.24e-04	121	146	6	GO:0009191
GeneOntologyBiologicalProcess	regulation of protein targeting to membrane	OGT USP17L2 HPCA KCNB1	2.40e-04	43	146	4	GO:0090313
GeneOntologyBiologicalProcess	nucleoside diphosphate catabolic process	OGT GIT1 SIRT6 CANT1 RPTOR ADPGK	2.55e-04	124	146	6	GO:0009134
GeneOntologyBiologicalProcess	taurine biosynthetic process	FMO3 CSAD	2.96e-04	4	146	2	GO:0042412
GeneOntologyBiologicalProcess	alkanesulfonate biosynthetic process	FMO3 CSAD	2.96e-04	4	146	2	GO:0046305
GeneOntologyBiologicalProcess	anterograde trans-synaptic signaling	GABRR2 GIT1 PCDHB14 GABRQ SYT2 ZZEF1 PIP5K1C PTCHD1 KCNB1 PLPPR4 AFDN SYT5 PRKCG TACR1 PLCG1 PICK1 EXOC4	3.24e-04	931	146	17	GO:0098916
GeneOntologyBiologicalProcess	chemical synaptic transmission	GABRR2 GIT1 PCDHB14 GABRQ SYT2 ZZEF1 PIP5K1C PTCHD1 KCNB1 PLPPR4 AFDN SYT5 PRKCG TACR1 PLCG1 PICK1 EXOC4	3.24e-04	931	146	17	GO:0007268
GeneOntologyBiologicalProcess	peptidyl-serine phosphorylation	OGT TFRC SMTNL1 LATS1 LATS2 RPTOR PRKCG PRKD1 CDK2	3.47e-04	307	146	9	GO:0018105
GeneOntologyBiologicalProcess	trans-synaptic signaling	GABRR2 GIT1 PCDHB14 GABRQ SYT2 ZZEF1 PIP5K1C PTCHD1 KCNB1 PLPPR4 AFDN SYT5 PRKCG TACR1 PLCG1 PICK1 EXOC4	3.57e-04	939	146	17	GO:0099537
GeneOntologyBiologicalProcess	purine nucleoside diphosphate metabolic process	OGT GIT1 SIRT6 RPTOR TJP2 ADPGK	3.57e-04	132	146	6	GO:0009135
GeneOntologyBiologicalProcess	purine ribonucleoside diphosphate metabolic process	OGT GIT1 SIRT6 RPTOR TJP2 ADPGK	3.57e-04	132	146	6	GO:0009179
GeneOntologyCellularComponent	nuclear outer membrane-endoplasmic reticulum membrane network	USP17L21 USP17L4 FMO3 USP17L2 USP17L12 USP17L1 USP17L20 USP17L11 ERO1A PON1 USP17L5 USP17L10 APOB USP17L19 USP17L18 SORT1 KSR1 USP17L17 CANT1 GUCY2C RGPD3 USP17L6P USP17L3 USP17L22 ADPGK USP17L15 SEC23A	7.97e-07	1327	150	27	GO:0042175
GeneOntologyCellularComponent	endoplasmic reticulum membrane	USP17L21 USP17L4 FMO3 USP17L2 USP17L12 USP17L1 USP17L20 USP17L11 ERO1A PON1 USP17L5 USP17L10 APOB USP17L19 USP17L18 SORT1 KSR1 USP17L17 CANT1 GUCY2C USP17L6P USP17L3 USP17L22 ADPGK USP17L15 SEC23A	1.64e-06	1293	150	26	GO:0005789
GeneOntologyCellularComponent	endoplasmic reticulum subcompartment	USP17L21 USP17L4 FMO3 USP17L2 USP17L12 USP17L1 USP17L20 USP17L11 ERO1A PON1 USP17L5 USP17L10 APOB USP17L19 USP17L18 SORT1 KSR1 USP17L17 CANT1 GUCY2C USP17L6P USP17L3 USP17L22 ADPGK USP17L15 SEC23A	1.79e-06	1299	150	26	GO:0098827
Domain	HABP4_PAI-RBP1	USP17L21 USP17L2 USP17L12 USP17L20 USP17L11 USP17L24 USP17L5 USP17L19 USP17L18 USP17L17 USP17L3 USP17L22	6.34e-23	16	147	12	PF04774
Domain	HABP4_PAIRBP1-bd	USP17L21 USP17L2 USP17L12 USP17L20 USP17L11 USP17L24 USP17L5 USP17L19 USP17L18 USP17L17 USP17L3 USP17L22	6.34e-23	16	147	12	IPR006861
Domain	UCH	USP17L21 USP13 USP17L4 USP17L2 USP17L12 USP17L1 USP17L20 USP17L11 USP17L24 USP17L5 USP17L10 USP17L19 USP17L18 USP17L17 USP17L3 USP17L22	2.08e-19	71	147	16	PF00443
Domain	USP_2	USP17L21 USP13 USP17L4 USP17L2 USP17L12 USP17L1 USP17L20 USP17L11 USP17L24 USP17L5 USP17L10 USP17L19 USP17L18 USP17L17 USP17L3 USP17L22	2.08e-19	71	147	16	PS00973
Domain	USP_3	USP17L21 USP13 USP17L4 USP17L2 USP17L12 USP17L1 USP17L20 USP17L11 USP17L24 USP17L5 USP17L10 USP17L19 USP17L18 USP17L17 USP17L3 USP17L22	2.66e-19	72	147	16	PS50235
Domain	USP_dom	USP17L21 USP13 USP17L4 USP17L2 USP17L12 USP17L1 USP17L20 USP17L11 USP17L24 USP17L5 USP17L10 USP17L19 USP17L18 USP17L17 USP17L3 USP17L22	2.66e-19	72	147	16	IPR028889
Domain	Peptidase_C19_UCH	USP17L21 USP13 USP17L4 USP17L2 USP17L12 USP17L1 USP17L20 USP17L11 USP17L24 USP17L5 USP17L10 USP17L19 USP17L18 USP17L17 USP17L3 USP17L22	2.66e-19	72	147	16	IPR001394
Domain	USP_CS	USP17L21 USP13 USP17L2 USP17L12 USP17L1 USP17L20 USP17L11 USP17L24 USP17L5 USP17L10 USP17L19 USP17L18 USP17L17 USP17L3 USP17L22	2.53e-18	66	147	15	IPR018200
Domain	USP_1	USP17L21 USP13 USP17L4 USP17L2 USP17L12 USP17L20 USP17L11 USP17L24 USP17L5 USP17L10 USP17L19 USP17L18 USP17L17 USP17L3 USP17L22	6.62e-18	70	147	15	PS00972
Domain	C2	SYT6 SYT2 SYT15B PIK3C2A SYT14 SYT5 PRKCG PLCG1 PLCE1	9.48e-07	131	147	9	PF00168
Domain	C2	SYT6 SYT2 SYT15B PIK3C2A SYT14 SYT5 PRKCG PLCG1 PLCE1	1.38e-06	137	147	9	SM00239
Domain	C2	SYT6 SYT2 SYT15B PIK3C2A SYT14 SYT5 PRKCG PLCG1 PLCE1	1.86e-06	142	147	9	PS50004
Domain	-	SYT6 SYT2 SYT15B PIK3C2A SYT14 SYT5 PRKCG PLCG1 PLCE1	2.62e-06	148	147	9	2.60.40.150
Domain	C2_dom	SYT6 SYT2 SYT15B PIK3C2A SYT14 SYT5 PRKCG PLCG1 PLCE1	6.09e-06	164	147	9	IPR000008
Domain	UBA	USP13 LATS1 LATS2 UBAP2L	1.78e-04	36	147	4	PF00627
Domain	UBA	USP13 LATS1 LATS2 UBAP2L	3.92e-04	44	147	4	IPR015940
Domain	PA	NAALADL1 TFRC EDEM3	4.22e-04	19	147	3	PF02225
Domain	PA_domain	NAALADL1 TFRC EDEM3	4.22e-04	19	147	3	IPR003137
Domain	Synaptotagmin	SYT6 SYT2 SYT5	4.94e-04	20	147	3	IPR001565
Domain	UBA	USP13 LATS1 LATS2 UBAP2L	5.05e-04	47	147	4	PS50030
Domain	TFR_dimer	NAALADL1 TFRC	9.04e-04	6	147	2	PF04253
Domain	-	NAALADL1 TFRC	9.04e-04	6	147	2	1.20.930.40
Domain	C1_1	DGKG KSR1 PRKCG PRKD1	1.05e-03	57	147	4	PF00130
Domain	PInositol-4-P-5-kinase	PIP5K1C PIP5KL1	1.26e-03	7	147	2	IPR023610
Domain	TFR-like_dimer_dom	NAALADL1 TFRC	1.26e-03	7	147	2	IPR007365
Domain	UBA-like	USP13 LATS1 LATS2 UBAP2L	1.62e-03	64	147	4	IPR009060
Domain	ZF_DAG_PE_1	DGKG KSR1 PRKCG PRKD1	1.62e-03	64	147	4	PS00479
Domain	ZF_DAG_PE_2	DGKG KSR1 PRKCG PRKD1	1.62e-03	64	147	4	PS50081
Domain	PIPKc	PIP5K1C PIP5KL1	1.67e-03	8	147	2	SM00330
Domain	-	PIP5K1C PIP5KL1	1.67e-03	8	147	2	3.30.800.10
Domain	PIP5K	PIP5K1C PIP5KL1	1.67e-03	8	147	2	PF01504
Domain	PIPK	PIP5K1C PIP5KL1	1.67e-03	8	147	2	PS51455
Domain	PInositol-4-P-5-kinase_N	PIP5K1C PIP5KL1	1.67e-03	8	147	2	IPR027484
Domain	PInositol-4-P-5-kinase_C	PIP5K1C PIP5KL1	1.67e-03	8	147	2	IPR027483
Domain	-	PIP5K1C PIP5KL1	1.67e-03	8	147	2	3.30.810.10
Domain	PInositol-4-P-5-kinase_core	PIP5K1C PIP5KL1	1.67e-03	8	147	2	IPR002498
Domain	C1	DGKG KSR1 PRKCG PRKD1	1.72e-03	65	147	4	SM00109
Domain	PE/DAG-bd	DGKG KSR1 PRKCG PRKD1	1.82e-03	66	147	4	IPR002219
Domain	RA	GRB14 AFDN PLCE1	1.83e-03	31	147	3	SM00314
Pathway	REACTOME_RAS_PROCESSING	USP17L21 USP17L4 USP17L2 USP17L12 USP17L1 USP17L20 USP17L11 USP17L5 USP17L10 USP17L19 USP17L18 USP17L17 USP17L6P USP17L3 USP17L22 USP17L15	1.07e-22	45	118	16	MM15671
Pathway	REACTOME_UB_SPECIFIC_PROCESSING_PROTEASES	USP17L21 USP13 USP17L4 USP17L2 USP17L12 USP17L1 USP17L20 USP17L11 USP17L5 USP17L10 USP17L19 USP17L18 USP17L17 USP17L6P USP17L3 USP17L22 USP17L15	3.61e-13	191	118	17	MM15289
Pathway	REACTOME_UB_SPECIFIC_PROCESSING_PROTEASES	USP17L21 USP13 USP17L4 USP17L2 USP17L12 USP17L1 USP17L20 USP17L11 USP17L24 USP17L5 USP17L10 USP17L19 USP17L18 USP17L17 USP17L3 USP17L22 USP17L15	3.89e-12	221	118	17	M27578
Pathway	REACTOME_DEUBIQUITINATION	USP17L21 USP13 USP17L4 OGT USP17L2 USP17L12 USP17L1 USP17L20 USP17L11 USP17L5 USP17L10 USP17L19 USP17L18 USP17L17 USP17L6P USP17L3 USP17L22 USP17L15	5.82e-12	262	118	18	MM15286
Pathway	REACTOME_DEUBIQUITINATION	USP17L21 USP13 USP17L4 OGT USP17L2 USP17L12 USP17L1 USP17L20 USP17L11 USP17L24 USP17L5 USP17L10 USP17L19 USP17L18 USP17L17 USP17L3 USP17L22 USP17L15	5.26e-11	299	118	18	M27574
Pathway	REACTOME_MAPK_FAMILY_SIGNALING_CASCADES	USP17L21 USP17L4 USP17L2 USP17L12 USP17L1 USP17L20 USP17L11 USP17L5 USP17L10 USP17L19 USP17L18 KSR1 USP17L17 USP17L6P USP17L3 USP17L22 USP17L15	1.18e-09	318	118	17	MM15278
Pathway	REACTOME_POST_TRANSLATIONAL_PROTEIN_MODIFICATION	USP17L21 USP13 USP17L4 CCDC22 OGT USP17L2 USP17L12 USP17L1 USP17L20 USP17L11 USP17L5 USP17L10 APOB USP17L19 BTBD1 TECTA USP17L18 NR1I2 USP17L17 VCAN RGPD3 USP17L6P USP17L3 FUCA2 USP17L22 FBXO21 USP17L15 SEC23A	8.13e-06	1389	118	28	MM15307
Pathway	REACTOME_POST_TRANSLATIONAL_PROTEIN_MODIFICATION	USP17L21 USP13 USP17L4 CCDC22 OGT USP17L2 USP17L12 USP17L1 USP17L20 USP17L11 USP17L24 USP17L5 USP17L10 APOB USP17L19 BTBD1 PPARG TECTA USP17L18 EDEM3 NR1I2 USP17L17 VCAN USP17L3 FUCA2 USP17L22 FBXO21 USP17L15 SEC23A	8.71e-06	1475	118	29	M19806
Pathway	KEGG_PHOSPHATIDYLINOSITOL_SIGNALING_SYSTEM	DGKG PIP5K1C PIK3C2A PRKCG PLCG1 PLCE1	4.11e-05	76	118	6	M9052
Pathway	REACTOME_CLATHRIN_MEDIATED_ENDOCYTOSIS	APOB SYT2 PIP5K1C TFRC PIK3C2A AGFG1 TACR1	1.89e-04	142	118	7	MM15499
Pathway	REACTOME_CLATHRIN_MEDIATED_ENDOCYTOSIS	APOB SYT2 PIP5K1C TFRC PIK3C2A AGFG1 TACR1	2.15e-04	145	118	7	M27753
Pathway	PID_ECADHERIN_STABILIZATION_PATHWAY	GIT1 PIP5K1C AFDN EXOC4	3.72e-04	41	118	4	M232
Pubmed	DUB-1, a deubiquitinating enzyme with growth-suppressing activity.	USP17L21 USP17L4 USP17L2 USP17L12 USP17L1 USP17L20 USP17L11 USP17L5 USP17L10 USP17L19 USP17L18 USP17L17 USP17L6P USP17L3 USP17L22 USP17L15	2.43e-34	21	156	16	8622927
Pubmed	DUB-1A, a novel deubiquitinating enzyme subfamily member, is polyubiquitinated and cytokine-inducible in B-lymphocytes.	USP17L21 USP17L4 USP17L2 USP17L12 USP17L1 USP17L20 USP17L11 USP17L5 USP17L10 USP17L19 USP17L18 USP17L17 USP17L6P USP17L3 USP17L22 USP17L15	2.43e-34	21	156	16	14583620
Pubmed	DUB-2A, a new member of the DUB subfamily of hematopoietic deubiquitinating enzymes.	USP17L21 USP17L4 USP17L2 USP17L12 USP17L1 USP17L20 USP17L11 USP17L5 USP17L10 USP17L19 USP17L18 USP17L17 USP17L6P USP17L3 USP17L22 USP17L15	2.43e-34	21	156	16	11468161
Pubmed	The murine DUB-1 gene is specifically induced by the betac subunit of interleukin-3 receptor.	USP17L21 USP17L4 USP17L2 USP17L12 USP17L1 USP17L20 USP17L11 USP17L5 USP17L10 USP17L19 USP17L18 USP17L17 USP17L6P USP17L3 USP17L22 USP17L15	2.43e-34	21	156	16	8756639
Pubmed	Lymphocyte-specific murine deubiquitinating enzymes induced by cytokines.	USP17L21 USP17L4 USP17L2 USP17L12 USP17L1 USP17L20 USP17L11 USP17L5 USP17L10 USP17L19 USP17L18 USP17L17 USP17L6P USP17L3 USP17L22 USP17L15	2.43e-34	21	156	16	12447969
Pubmed	DUB-1, a fate determinant of dynein heavy chain in B-lymphocytes, is regulated by the ubiquitin-proteasome pathway.	USP17L21 USP17L4 USP17L2 USP17L12 USP17L1 USP17L20 USP17L11 USP17L5 USP17L10 USP17L19 USP17L18 USP17L17 USP17L6P USP17L3 USP17L22 USP17L15	2.43e-34	21	156	16	18980247
Pubmed	JAK2 is required for induction of the murine DUB-1 gene.	USP17L21 USP17L4 USP17L2 USP17L12 USP17L1 USP17L20 USP17L11 USP17L5 USP17L10 USP17L19 USP17L18 USP17L17 USP17L6P USP17L3 USP17L22 USP17L15	8.86e-34	22	156	16	9154835
Pubmed	DUB-2 is a member of a novel family of cytokine-inducible deubiquitinating enzymes.	USP17L21 USP17L4 USP17L2 USP17L12 USP17L1 USP17L20 USP17L11 USP17L5 USP17L10 USP17L19 USP17L18 USP17L17 USP17L6P USP17L3 USP17L22 USP17L15	8.67e-33	24	156	16	8995226
Pubmed	Interleukin 1 receptor signaling regulates DUBA expression and facilitates Toll-like receptor 9-driven antiinflammatory cytokine production.	USP17L21 USP17L4 USP17L2 USP17L12 USP17L1 USP17L20 USP17L11 USP17L5 USP17L10 USP17L19 USP17L18 USP17L17 USP17L6P USP17L3 USP17L22 USP17L15	2.40e-32	25	156	16	21115691
Pubmed	Cdc25A and Dub3 in a high-stakes balancing act.	USP17L21 USP17L4 USP17L2 USP17L12 USP17L1 USP17L20 USP17L11 USP17L24 USP17L5 USP17L10 USP17L19 USP17L18 USP17L17 USP17L6P USP17L3 USP17L22 USP17L15	5.38e-32	33	156	17	20228807
Pubmed	Decabromodiphenyl ethane affects embryonic development by interfering with nuclear F-actin in zygotes and leads to cognitive and social disorders in offspring mice.	USP17L21 USP17L4 USP17L2 USP17L12 USP17L1 USP17L20 USP17L11 USP17L5 USP17L10 USP17L19 USP17L18 USP17L17 USP17L6P USP17L3 USP17L22 USP17L15	6.21e-32	26	156	16	35816173
Pubmed	The DUB/USP17 deubiquitinating enzymes: a gene family within a tandemly repeated sequence, is also embedded within the copy number variable beta-defensin cluster.	USP17L21 USP17L4 USP17L2 USP17L12 USP17L1 USP17L20 USP17L11 USP17L24 USP17L5 USP17L10 USP17L19 USP17L18 USP17L17 USP17L6P USP17L3 USP17L22 USP17L15	1.07e-31	34	156	17	20403174
Pubmed	DUB-3, a cytokine-inducible deubiquitinating enzyme that blocks proliferation.	USP17L21 USP17L4 USP17L2 USP17L12 USP17L1 USP17L20 USP17L11 USP17L24 USP17L5 USP17L10 USP17L19 USP17L18 USP17L17 USP17L6P USP17L3 USP17L22 USP17L15	1.07e-31	34	156	17	14699124
Pubmed	The DUB/USP17 deubiquitinating enzymes, a multigene family within a tandemly repeated sequence.	USP17L21 USP17L4 USP17L2 USP17L12 USP17L1 USP17L20 USP17L11 USP17L24 USP17L5 USP17L10 USP17L19 USP17L18 USP17L17 USP17L6P USP17L3 USP17L22 USP17L15	1.07e-31	34	156	17	15780755
Pubmed	USP17 regulates Ras activation and cell proliferation by blocking RCE1 activity.	USP17L21 USP17L4 USP17L2 USP17L12 USP17L1 USP17L20 USP17L11 USP17L24 USP17L5 USP17L10 USP17L19 USP17L18 USP17L17 USP17L6P USP17L3 USP17L22 USP17L15	1.07e-31	34	156	17	19188362
Pubmed	Unstable transmission of the RS447 human megasatellite tandem repetitive sequence that contains the USP17 deubiquitinating enzyme gene.	USP17L21 USP17L4 USP17L2 USP17L12 USP17L1 USP17L20 USP17L11 USP17L24 USP17L5 USP17L10 USP17L19 USP17L18 USP17L17 USP17L6P USP17L3 USP17L22 USP17L15	1.07e-31	34	156	17	11941478
Pubmed	Hyaluronan- and RNA-binding deubiquitinating enzymes of USP17 family members associated with cell viability.	USP17L21 USP17L4 USP17L2 USP17L12 USP17L1 USP17L20 USP17L11 USP17L24 USP17L5 USP17L10 USP17L19 USP17L18 USP17L17 USP17L6P USP17L3 USP17L22 USP17L15	1.07e-31	34	156	17	17109758
Pubmed	The deubiquitinating enzyme USP17 is highly expressed in tumor biopsies, is cell cycle regulated, and is required for G1-S progression.	USP17L21 USP17L4 USP17L2 USP17L12 USP17L1 USP17L20 USP17L11 USP17L24 USP17L5 USP17L10 USP17L19 USP17L18 USP17L17 USP17L6P USP17L3 USP17L22 USP17L15	1.07e-31	34	156	17	20388806
Pubmed	Polyclonal and monoclonal antibodies specific for USP17, a proapoptotic deubiquitinating enzyme.	USP17L21 USP17L4 USP17L2 USP17L12 USP17L1 USP17L20 USP17L11 USP17L24 USP17L5 USP17L10 USP17L19 USP17L18 USP17L17 USP17L6P USP17L3 USP17L22 USP17L15	1.07e-31	34	156	17	20715989
Pubmed	Human megasatellite DNA RS447: copy-number polymorphisms and interspecies conservation.	USP17L21 USP17L4 USP17L2 USP17L12 USP17L1 USP17L20 USP17L11 USP17L24 USP17L5 USP17L10 USP17L19 USP17L18 USP17L17 USP17L6P USP17L3 USP17L22 USP17L15	1.07e-31	34	156	17	9806828
Pubmed	The ubiquitin-specific protease 17 is involved in virus-triggered type I IFN signaling.	USP17L21 USP17L4 USP17L2 USP17L12 USP17L1 USP17L20 USP17L11 USP17L24 USP17L5 USP17L10 USP17L19 USP17L18 USP17L17 USP17L6P USP17L3 USP17L22 USP17L15	1.07e-31	34	156	17	20368735
Pubmed	The RS447 human megasatellite tandem repetitive sequence encodes a novel deubiquitinating enzyme with a functional promoter.	USP17L21 USP17L4 USP17L2 USP17L12 USP17L1 USP17L20 USP17L11 USP17L24 USP17L5 USP17L10 USP17L19 USP17L18 USP17L17 USP17L6P USP17L3 USP17L22 USP17L15	1.07e-31	34	156	17	10936051
Pubmed	The deubiquitinating enzyme USP17 is essential for GTPase subcellular localization and cell motility.	USP17L21 USP17L4 USP17L2 USP17L12 USP17L1 USP17L20 USP17L11 USP17L24 USP17L5 USP17L10 USP17L19 USP17L18 USP17L17 USP17L6P USP17L3 USP17L22 USP17L15	1.07e-31	34	156	17	21448158
Pubmed	Cytokine-regulated protein degradation by the ubiquitination system.	USP17L21 USP17L4 USP17L2 USP17L12 USP17L1 USP17L20 USP17L11 USP17L24 USP17L5 USP17L10 USP17L19 USP17L18 USP17L17 USP17L6P USP17L3 USP17L22 USP17L15	2.07e-31	35	156	17	16611142
Pubmed	Lys-63-specific deubiquitination of SDS3 by USP17 regulates HDAC activity.	USP17L21 USP17L4 USP17L2 USP17L12 USP17L1 USP17L20 USP17L11 USP17L24 USP17L5 USP17L10 USP17L19 USP17L18 USP17L17 USP17L6P USP17L3 USP17L22 USP17L15	2.07e-31	35	156	17	21239494
Pubmed	The deubiquitinating enzyme USP17 blocks N-Ras membrane trafficking and activation but leaves K-Ras unaffected.	USP17L21 USP17L4 USP17L2 USP17L12 USP17L1 USP17L20 USP17L11 USP17L24 USP17L5 USP17L10 USP17L19 USP17L18 USP17L17 USP17L6P USP17L3 USP17L22 USP17L15	3.92e-31	36	156	17	20147298
Pubmed	Ubiquitin hydrolase Dub3 promotes oncogenic transformation by stabilizing Cdc25A.	USP17L21 USP17L4 USP17L2 USP17L12 USP17L1 USP17L20 USP17L11 USP17L24 USP17L5 USP17L10 USP17L19 USP17L18 USP17L17 USP17L6P USP17L3 USP17L22 USP17L15	7.22e-31	37	156	17	20228808
Pubmed	Minor Splicing Factors Zrsr1 and Zrsr2 Are Essential for Early Embryo Development and 2-Cell-Like Conversion.	USP17L21 USP17L4 USP17L2 USP17L12 USP17L1 USP17L20 USP17L11 USP17L5 USP17L10 USP17L19 USP17L18 USP17L17 USP17L6P USP17L3 USP17L22 USP17L15	7.85e-31	29	156	16	32527007
Pubmed	DUX is a non-essential synchronizer of zygotic genome activation.	USP17L21 USP17L4 USP17L2 USP17L12 USP17L1 USP17L20 USP17L11 USP17L5 USP17L10 USP17L19 USP17L18 USP17L17 USP17L6P USP17L3 USP17L22 USP17L15	5.26e-26	50	156	16	31806660
Pubmed	High Dub3 expression in mouse ESCs couples the G1/S checkpoint to pluripotency.	USP17L4 USP17L2 USP17L1 USP17L6P USP17L3 USP17L15	1.53e-12	10	156	6	24207026
Pubmed	Cell cycle-dependent expression of Dub3, Nanog and the p160 family of nuclear receptor coactivators (NCoAs) in mouse embryonic stem cells.	USP17L4 USP17L2 USP17L1 USP17L6P USP17L3 USP17L15	6.68e-12	12	156	6	24695638
Pubmed	ES cell neural differentiation reveals a substantial number of novel ESTs.	USP17L4 USP17L2 USP17L1 USP17L6P USP17L3 USP17L15	2.16e-11	14	156	6	11793228
Pubmed	CDK4/6-dependent activation of DUB3 regulates cancer metastasis through SNAIL1.	USP17L4 USP17L2 USP17L1 USP17L6P USP17L3 USP17L15	1.91e-10	19	156	6	28067227
Pubmed	USP7 represses lineage differentiation genes in mouse embryonic stem cells by both catalytic and noncatalytic activities.	USP17L21 USP17L4 USP17L2 USP17L12 USP17L1 USP17L20 USP17L11 USP17L5 USP17L10 USP17L19 NKRF USP17L18 USP17L17 USP17L6P USP17L3 USP17L22 PRDM14 USP17L15	1.67e-09	674	156	18	37196079
Pubmed	Human and mouse proteases: a comparative genomic approach.	USP13 USP17L4 NAALADL1 USP17L2 USP17L1 USP17L6P USP17L3 USP17L15	3.33e-09	81	156	8	12838346
Pubmed	Cytoplasmic ASPP1 inhibits apoptosis through the control of YAP.	PPP1R13B LATS1 LATS2	3.53e-07	4	156	3	21041411
Pubmed	RASSF1A-LATS1 signalling stabilizes replication forks by restricting CDK2-mediated phosphorylation of BRCA2.	LATS1 BRCA2 CDK2	8.79e-07	5	156	3	25218637
Pubmed	A Genome-Wide CRISPR Screen Identifies Genes Critical for Resistance to FLT3 Inhibitor AC220.	USP17L21 USP17L12 USP17L20 USP17L11 USP17L19 USP17L18 USP17L17	1.17e-06	119	156	7	28625976
Pubmed	Identification of synaptotagmin effectors via acute inhibition of secretion from cracked PC12 cells.	SYT6 SYT2 SYT5	1.75e-06	6	156	3	12860971
Pubmed	Phospholipid composition dependence of Ca2+-dependent phospholipid binding to the C2A domain of synaptotagmin IV.	SYT6 SYT2 SYT5	1.75e-06	6	156	3	8626542
Pubmed	Release of calcium from inositol 1,4,5-trisphosphate receptor-regulated stores by HIV-1 Tat regulates TNF-alpha production in human macrophages.	PRKCG PRKD1 PLCG1 PLCE1	3.86e-06	24	156	4	10843712
Pubmed	Mechanism of HIV-1-TAT induction of interleukin-1beta from human monocytes: Involvement of the phospholipase C/protein kinase C signaling cascade.	PRKCG PRKD1 PLCG1 PLCE1	6.31e-06	27	156	4	20336759
Pubmed	Distinct developmental expression of synaptotagmin I and IX in the mouse brain.	SYT6 SYT2 SYT5	7.29e-06	9	156	3	16407767
Pubmed	Mirror image motifs mediate the interaction of the COOH terminus of multiple synaptotagmins with the neurexins and calmodulin.	SYT6 SYT2 SYT5	7.29e-06	9	156	3	8901523
Pubmed	Pharmacogenetic analysis of lipid responses to rosuvastatin in Chinese patients.	FMO3 PON1 APOB PPARG SORT1	1.22e-05	66	156	5	20679960
Pubmed	PPARγ-induced upregulation of subcutaneous fat adiponectin secretion, glyceroneogenesis and BCAA oxidation requires mTORC1 activity.	PPARG RPTOR	2.00e-05	2	156	2	34004356
Pubmed	Mutation analysis of large tumor suppressor genes LATS1 and LATS2 supports a tumor suppressor role in human cancer.	LATS1 LATS2	2.00e-05	2	156	2	25482410
Pubmed	Lats1/2-Mediated Alteration of Hippo Signaling Pathway Regulates the Fate of Bone Marrow-Derived Mesenchymal Stem Cells.	LATS1 LATS2	2.00e-05	2	156	2	30671453
Pubmed	FKBP51 Null Mice Are Resistant to Diet-Induced Obesity and the PPARγ Agonist Rosiglitazone.	PPARG FKBP5	2.00e-05	2	156	2	27442117
Pubmed	Adipocyte OGT governs diet-induced hyperphagia and obesity.	OGT PPARG	2.00e-05	2	156	2	30504766
Pubmed	Hepatic sortilin regulates both apolipoprotein B secretion and LDL catabolism.	APOB SORT1	2.00e-05	2	156	2	22751103
Pubmed	A single copy of large tumor suppressor 1 or large tumor suppressor 2 is sufficient for normal hematopoiesis.	LATS1 LATS2	2.00e-05	2	156	2	32826458
Pubmed	AICAR Antiproliferative Properties Involve the AMPK-Independent Activation of the Tumor Suppressors LATS 1 and 2.	LATS1 LATS2	2.00e-05	2	156	2	29730476
Pubmed	Association of paraoxonase1 gene Q192R polymorphism and apolipoprotein B in Asian Indian women with coronary artery disease risk.	PON1 APOB	2.00e-05	2	156	2	23171143
Pubmed	N-terminal truncation of Lats1 causes abnormal cell growth control and chromosomal instability.	LATS1 LATS2	2.00e-05	2	156	2	23230145
Pubmed	A major locus for autosomal recessive retinitis pigmentosa on 6q, determined by homozygosity mapping of chromosomal regions that contain gamma-aminobutyric acid-receptor clusters.	GABRR2 EYS	2.00e-05	2	156	2	9585594
Pubmed	LATS1 but not LATS2 represses autophagy by a kinase-independent scaffold function.	LATS1 LATS2	2.00e-05	2	156	2	31848340
Pubmed	Expression of LATS family proteins in ovarian tumors and its significance.	LATS1 LATS2	2.00e-05	2	156	2	25841306
Pubmed	Evidence for a tumor suppressor role for the large tumor suppressor genes LATS1 and LATS2 in human cancer.	LATS1 LATS2	2.00e-05	2	156	2	24026096
Pubmed	Neurocalcin family: a novel calcium-binding protein abundant in bovine central nervous system.	HPCA HPCAL1	2.00e-05	2	156	2	8387172
Pubmed	Association analysis between SNPs in LATS1 and LATS2 and non-cardia gastric cancer.	LATS1 LATS2	2.00e-05	2	156	2	32423384
Pubmed	Deletion of Lats1/2 in adult kidney epithelia leads to renal cell carcinoma.	LATS1 LATS2	2.00e-05	2	156	2	34060480
Pubmed	Promoter hypermethylation-mediated down-regulation of LATS1 and LATS2 in human astrocytoma.	LATS1 LATS2	2.00e-05	2	156	2	17049657
Pubmed	Contribution of ApoB-100/SORT1-Mediated Immune Microenvironment in Regulating Oxidative Stress, Inflammation, and Ferroptosis After Spinal Cord Injury.	APOB SORT1	2.00e-05	2	156	2	38337131
Pubmed	Lats1 and Lats2 are required for ovarian granulosa cell fate maintenance.	LATS1 LATS2	2.00e-05	2	156	2	31268774
Pubmed	The Hippo pathway regulates human megakaryocytic differentiation.	LATS1 LATS2	2.00e-05	2	156	2	27786336
Pubmed	FKBP5 activates mitophagy by ablating PPAR-γ to shape a benign remyelination environment.	PPARG FKBP5	2.00e-05	2	156	2	37952053
Pubmed	Cell type-dependent function of LATS1/2 in cancer cell growth.	LATS1 LATS2	2.00e-05	2	156	2	30531839
Pubmed	Down-regulation of LATS1 and LATS2 mRNA expression by promoter hypermethylation and its association with biologically aggressive phenotype in human breast cancers.	LATS1 LATS2	2.00e-05	2	156	2	15746036
Pubmed	Exome sequencing: an efficient diagnostic tool for complex neurodegenerative disorders.	APOB SACS	2.00e-05	2	156	2	23043354
Pubmed	Identification of LATS transcriptional targets in HeLa cells using whole human genome oligonucleotide microarray.	LATS1 LATS2	2.00e-05	2	156	2	19799973
Pubmed	LATS suppresses mTORC1 activity to directly coordinate Hippo and mTORC1 pathways in growth control.	LATS1 LATS2	2.00e-05	2	156	2	32015438
Pubmed	A novel immuno-competitive capture mass spectrometry strategy for protein-protein interaction profiling reveals that LATS kinases regulate HCV replication through NS5A phosphorylation.	LATS1 LATS2	2.00e-05	2	156	2	25044019
Pubmed	Signaling pathways triggered by HIV-1 Tat in human monocytes to induce TNF-alpha.	PRKCG PRKD1 PLCG1 PLCE1	2.55e-05	38	156	4	12482669
Pubmed	ESCPE-1 mediates retrograde endosomal sorting of the SARS-CoV-2 host factor Neuropilin-1.	NEMP1 FRAS1 ERO1A ARFGEF1 CACHD1 WDR25 ZZEF1 PLXNB2 TFRC SORT1 EDEM3 COCH CANT1 SVIL CPSF1 FUCA2 ADPGK	3.02e-05	1201	156	17	35696571
Pubmed	Robust phosphoproteomic profiling of tyrosine phosphorylation sites from human T cells using immobilized metal affinity chromatography and tandem mass spectrometry.	LATS1 UBAP2L TJP2 AFDN PLCG1 CDK2	3.17e-05	133	156	6	15144186
Pubmed	Interaction network of human early embryonic transcription factors.	NEMP1 OGT TFRC SORT1 ZNF462 ZFHX4 BAZ1A MCM3AP RERE	3.18e-05	351	156	9	38297188
Pubmed	A central chaperone-like role for 14-3-3 proteins in human cells.	GIT1 KDM3B KSR1 LATS1 TCERG1 PIK3C2A RPTOR SVIL AGFG1 TJP2 NHS AFDN PRKCG EXOC4	3.63e-05	861	156	14	36931259
Pubmed	An FAK-YAP-mTOR Signaling Axis Regulates Stem Cell-Based Tissue Renewal in Mice.	LATS1 LATS2 RPTOR	3.87e-05	15	156	3	28457749
Pubmed	SRCAP complex promotes lung cancer progression by reprograming the oncogenic transcription of Hippo-YAP/TAZ signaling pathway.	CCDC22 OGT KDM3B PPP1R13B NKRF LATS1 TCERG1 UBAP2L TJP2 AFDN EXOC4	4.08e-05	549	156	11	38280479
Pubmed	Nell1-deficient mice have reduced expression of extracellular matrix proteins causing cranial and vertebral defects.	DGKG PPARG VCAN PRKCG PRKD1 PLCG1 PICK1	4.82e-05	210	156	7	16537572
Pubmed	Sex-stratified genome-wide association studies including 270,000 individuals show sexual dimorphism in genetic loci for anthropometric traits.	GRB14 PPARG TACR1	5.75e-05	17	156	3	23754948
Pubmed	Role of phospholipase Cgamma1 in cell spreading requires association with a beta-Pix/GIT1-containing complex, leading to activation of Cdc42 and Rac1.	GIT1 PLCG1	5.98e-05	3	156	2	17562871
Pubmed	A FUS-LATS1/2 Axis Inhibits Hepatocellular Carcinoma Progression via Activating Hippo Pathway.	LATS1 LATS2	5.98e-05	3	156	2	30308519
Pubmed	Eicosapentaenoic acid upregulates VEGF-A through both GPR120 and PPARγ mediated pathways in 3T3-L1 adipocytes.	PPARG FFAR4	5.98e-05	3	156	2	25697344
Pubmed	SIRT6 transcriptionally regulates fatty acid transport by suppressing PPARγ.	SIRT6 PPARG	5.98e-05	3	156	2	34077730
Pubmed	Spatial organization of Hippo signaling at the plasma membrane mediated by the tumor suppressor Merlin/NF2.	LATS1 LATS2	5.98e-05	3	156	2	24012335
Pubmed	Phosphoregulation of the titin-cap protein telethonin in cardiac myocytes.	PIK3C2A PRKD1	5.98e-05	3	156	2	24280220
Pubmed	Effect of SORT1, APOB and APOE polymorphisms on LDL-C and coronary heart disease in Pakistani subjects and their comparison with Northwick Park Heart Study II.	APOB SORT1	5.98e-05	3	156	2	27112212
Pubmed	Expression of phospholipase C isozymes in human breast cancer and their clinical significance.	PLCG1 PLCE1	5.98e-05	3	156	2	28112359
Pubmed	Precise Regulation of the Basal PKCγ Activity by DGKγ Is Crucial for Motor Coordination.	DGKG PRKCG	5.98e-05	3	156	2	33114041
Pubmed	LATS kinases and SLUG regulate the transition to advanced stage in aggressive oral cancer cells.	LATS1 LATS2	5.98e-05	3	156	2	35859006
Pubmed	A novel alternatively spliced variant of synaptotagmin VI lacking a transmembrane domain. Implications for distinct functions of the two isoforms.	SYT6 SYT5	5.98e-05	3	156	2	10531344
Pubmed	Protein kinase C{gamma} mediates regulation of proliferation by the serotonin 5-hydroxytryptamine receptor 2B.	PRKCG PLCG1	5.98e-05	3	156	2	19531484
Pubmed	Chlamydia pneumoniae induces macrophage-derived foam cell formation via PPAR alpha and PPAR gamma-dependent pathways.	APOB PPARG	5.98e-05	3	156	2	19114110
Pubmed	PPARγ-mediated G-protein coupled receptor 120 signaling pathway promotes transcriptional activation of miR-143 in adipocytes.	PPARG FFAR4	5.98e-05	3	156	2	28495174
Pubmed	Cyclin-dependent kinase 2 negatively regulates human pregnane X receptor-mediated CYP3A4 gene expression in HepG2 liver carcinoma cells.	NR1I2 CDK2	5.98e-05	3	156	2	18784074
Pubmed	FKBP51 reciprocally regulates GRα and PPARγ activation via the Akt-p38 pathway.	PPARG FKBP5	5.98e-05	3	156	2	24933248
Pubmed	Grb14 inhibits FGF receptor signaling through the regulation of PLCγ recruitment and activation.	GRB14 PLCG1	5.98e-05	3	156	2	20932831
Pubmed	The Lupus Susceptibility Locus Sgp3 Encodes the Suppressor of Endogenous Retrovirus Expression SNERV.	ZNF709 ZNF433	5.98e-05	3	156	2	30709743
Cytoband	4p16.1	USP17L21 USP17L23 USP17L12 USP17L20 USP17L11 USP17L24 USP17L5 USP17L10 USP17L19 USP17L18 USP17L17 USP17L6P USP17L22 USP17L15	1.55e-20	79	156	14	4p16.1
Cytoband	Ensembl 112 genes in cytogenetic band chr4p16	USP17L21 USP17L23 USP17L12 USP17L20 USP17L11 USP17L24 USP17L5 USP17L10 USP17L19 USP17L18 USP17L17 USP17L6P USP17L22 USP17L15	4.39e-14	222	156	14	chr4p16
GeneFamily	Synaptotagmins	SYT6 SYT2 SYT14 SYT5	1.68e-06	17	96	4	765
Coexpression	MADAN_DPPA4_TARGETS	USP17L21 USP17L4 USP17L2 USP17L12 USP17L1 USP17L20 USP17L11 USP17L5 USP17L10 USP17L19 USP17L18 USP17L17 USP17L6P USP17L3 USP17L22 USP17L15	6.17e-20	86	154	16	MM1312
Coexpression	GERY_CEBP_TARGETS	USP17L21 USP17L4 USP17L2 USP17L12 USP17L1 USP17L20 USP17L11 USP17L5 USP17L10 USP17L19 PPARG TFRC USP17L18 USP17L17 VCAN USP17L6P USP17L3 USP17L22 USP17L15	1.32e-19	160	154	19	MM1155
Coexpression	GRAESSMANN_RESPONSE_TO_MC_AND_SERUM_DEPRIVATION_DN	USP17L21 USP17L4 USP17L2 USP17L12 USP17L1 USP17L20 USP17L11 ERO1A USP17L5 USP17L10 USP17L19 USP17L18 USP17L17 USP17L6P USP17L3 USP17L22 USP17L15	1.60e-19	112	154	17	MM1095
Coexpression	BRUINS_UVC_RESPONSE_LATE	USP17L21 USP17L4 CCDC22 USP17L2 USP17L12 USP17L1 POLM USP17L20 USP17L11 MYO1H PPP1R13B USP17L5 USP17L10 USP17L19 USP17L18 HPCA USP17L17 HPCAL1 PARVA USP17L6P RNF38 USP17L3 TJP2 AFDN USP17L22 USP17L15 PICK1	1.75e-09	1198	154	27	MM1062
Coexpression	GRAESSMANN_RESPONSE_TO_MC_AND_DOXORUBICIN_UP	USP17L21 USP17L4 USP17L2 USP17L12 USP17L1 USP17L20 USP17L11 MYO1H USP17L5 USP17L10 USP17L19 PLXNB2 USP17L18 USP17L17 USP17L6P USP17L3 USP17L22 USP17L15 EXOC4	9.32e-09	647	154	19	MM981
Coexpression	GRAESSMANN_APOPTOSIS_BY_DOXORUBICIN_UP	USP17L21 USP17L4 USP17L2 USP17L12 USP17L1 USP17L20 USP17L11 MYO1H USP17L5 USP17L10 USP17L19 PLXNB2 PEX26 USP17L18 USP17L17 USP17L6P USP17L3 UPP1 USP17L22 USP17L15 KIF22 EXOC4	3.06e-06	1226	154	22	MM979
Coexpression	FIRESTEIN_PROLIFERATION	PPARG NR1I2 GUCY2C SYT14 SYT5 PRKCG PRKD1 PICK1	6.51e-06	166	154	8	M5354
Coexpression	MARSON_BOUND_BY_FOXP3_STIMULATED	USP17L21 USP17L4 OGT USP17L2 USP17L12 USP17L1 USP17L20 USP17L11 PPP1R13B USP17L5 USP17L10 USP17L19 USP17L18 USP17L17 UBAP2L USP17L6P USP17L3 USP17L22 USP17L15	1.82e-05	1072	154	19	MM1031
Coexpression	FOURATI_BLOOD_TWINRIX_AGE_25_83YO_RESPONDERS_VS_POOR_RESPONDERS_0DY_DN	DGKG SIRT6 PPARG SORT1 LATS2 TCERG1 VCAN AGFG1 TJP2 AFDN SYT5 PRKD1 FUCA2 RERE PLCE1	3.58e-05	746	154	15	M40863
ToppCell	human_hepatoblastoma-Tumor_cells-T5\|Tumor_cells / Sample and Cell Type and Tumor Cluster (all cells)	PCSK2 FRAS1 CACHD1 ZNF462 PIK3C2A VCAN NHS RERE MGAT5B	1.42e-08	188	148	9	b070a0667f1ee9b825b267b6c389b7c42fc436f9
ToppCell	pdx-Tumor_cells-T5\|Tumor_cells / Sample and Cell Type and Tumor Cluster (all cells)	PCSK2 SLC6A16 CACHD1 ZNF462 PIK3C2A VCAN NHS RERE	2.20e-07	187	148	8	7e376831a11ee72ed87abcdac631ca46ae29c250
ToppCell	LA-13._Vascular_Smooth_Muscle\|LA / Chamber and Cluster_Paper	A2M FAT3 DGKG SORT1 PTCHD1 SVIL NHS PRKD1	2.29e-07	188	148	8	34e1b074a3995aa46ab194eb45115d76d1a5514d
ToppCell	metastatic_Lymph_Node-Myeloid_cells-Alveolar_Mac\|Myeloid_cells / Location, Cell class and cell subclass	B3GALT1 MEIOB CCDC168 PPARG TECTA FFAR4 TFRC	4.73e-07	141	148	7	399380de5ea09e22fd128e3e55fffeffc4874c15
ToppCell	LV-13._Vascular_Smooth_Muscle\|LV / Chamber and Cluster_Paper	A2M PCSK2 DGKG SORT1 PTCHD1 NHS PLCE1	1.73e-06	171	148	7	e99ecae66530d1ae09330cee408c8f3950b87e67
ToppCell	3'-Broncho-tracheal-Immune_Myeloid-Myeloid_macrophage-alveolar_macrophage-Alveolar_macrophages-Alveolar_macrophages_L.1.0.3.1\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	PPARG FFAR4 TFRC SORT1 SVIL ADGRE1 ADPGK	2.25e-06	178	148	7	0b398656f26c4061b11ccf98908d0e2e1367585a
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic-thymocyte\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	A2M FRAS1 DNAH10 FAT3 APOB ZFHX4 PLCE1	2.81e-06	184	148	7	2cbed6462fea2622871bb7e49b0df3d984239281
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	A2M FRAS1 DNAH10 FAT3 APOB ZFHX4 PLCE1	2.81e-06	184	148	7	ea7a7e2bac46d4d2c31a5d576b38a032b5335062
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic-proliferating_thymocyte;_DN_to_DP_transition,_dividing_(some_are_Cd8+/_Cd4+,_some_undergoing_VDJ_recombination)\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	A2M FRAS1 DNAH10 FAT3 APOB ZFHX4 PLCE1	2.81e-06	184	148	7	2b19a8c5f823e00812908b23e66bb4e563278aff
ToppCell	10x3'2.3-week_14-16-Mesenchymal_myocytic-stroma-muscle_stem_cell\|week_14-16 / cell types per 3 fetal stages;per 3',per 5'	A2M FRAS1 FAT3 SYT15B ZFHX4 PARVA PRKD1	3.23e-06	188	148	7	de6f4889e0c5f39fbbaefd85526f645c6afa09d5
ToppCell	Striatum-Neuronal-Excitatory-eN3(Slc17a7_Gad1Gad2)\|Striatum / BrainAtlas - Mouse McCarroll V32	PCSK2 FRAS1 HPCA PTCHD1 PLPPR4 SYT5 PRKCG	3.23e-06	188	148	7	e34ea7014c5a059a7db38f78bd903cf02616ddd3
ToppCell	LA-13._Vascular_Smooth_Muscle\|World / Chamber and Cluster_Paper	A2M FAT3 DGKG SORT1 PTCHD1 NHS PRKD1	3.35e-06	189	148	7	6b3e88751b95fc2173f2c3d5061ed632d0c5f01c
ToppCell	TCGA-Brain-Primary_Tumor-Low_Grade_Glioma-Oligoastrocytoma-3\|TCGA-Brain / Sample_Type by Project: Shred V9	PRSS35 FOXR1 SYT6 CCDC168 EYS VCAN	6.06e-06	135	148	6	3351e8b9e417397c5fa9f856184ff24ce1a27242
ToppCell	Fetal_brain-organoid_Tanaka_cellReport-GW10-OPC_related-Oligodendrocyte/OPC\|GW10 / Sample Type, Dataset, Time_group, and Cell type.	PRSS35 PCDHB14 GRB14 TLR6 PTCHD1 TJP2	1.15e-05	151	148	6	4533bccc996395f74b16af939ce79b6fe253c073
ToppCell	Fetal_brain-organoid_Tanaka_cellReport-GW10-OPC_related\|GW10 / Sample Type, Dataset, Time_group, and Cell type.	PRSS35 PCDHB14 GRB14 TLR6 PTCHD1 TJP2	1.15e-05	151	148	6	edb2f59789c295838d2030b80c792cbea25eaa3d
ToppCell	droplet-Liver-LIVER_HEPATOCYTES-30m-Myeloid\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DNAH10 MYO1H SYT2 PTCHD1 VCAN NHS	1.29e-05	154	148	6	1e32969bee810adaf2d560f0824a16227df513d8
ToppCell	NS-moderate-d_07-13-Epithelial-FOXN4+\|d_07-13 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	USP13 RSPH10B2 BRCA2 SYT5 PRKD1 PLCE1	1.44e-05	157	148	6	410c9d74a2085179cfb39853cb6d330fa98c9c1b
ToppCell	PBMC-Control-Myeloid-Neutrophil-Neutrophil-\|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)	DGKG WDR25 COCH FAM157C RGPD3 ADGRE1	1.60e-05	160	148	6	70f3637dd0bcfcef421aa114f946fff0048f192e
ToppCell	LV-13._Vascular_Smooth_Muscle\|World / Chamber and Cluster_Paper	A2M PCSK2 DGKG SORT1 PTCHD1 NHS	1.90e-05	165	148	6	f37fd95adc95d7753cf6e55ae819976513c7ec77
ToppCell	Primary_Motor_Cortex_(M1)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_D_(IT_RORB_THEMIS_LINC00507)_2\|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	FAT3 GRB14 CCDC168 HPCA C12orf42 MGAT5B	3.01e-05	179	148	6	8766a5a066091879f521acfc612abf563ff78808
ToppCell	facs-Heart-RA-24m-Mesenchymal-smooth_muscle_cell\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GABRQ GRB14 KCNB1 SYT5 HSPB2 PLCE1	3.01e-05	179	148	6	d76a05f1fee7f2f7b7b7994d3622e96f02b49432
ToppCell	facs-Heart-RA-24m-Mesenchymal-smooth_muscle_cell\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GABRQ GRB14 KCNB1 SYT5 HSPB2 PLCE1	3.01e-05	179	148	6	6be47c877250968a916c711ba0787eb7b4c5443d
ToppCell	droplet-Kidney-nan-3m-Mesenchymal-podocyte\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PCDHB14 GRB14 COCH ZFHX4 VCAN HSPB2	3.20e-05	181	148	6	0b1e7335648823b1d83bdfa878ccd44efe7bba9a
ToppCell	facs-Brain_Non-Myeloid-Cortex-3m-Neuronal-medium_spiny_neuron\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FRAS1 SYT6 HPCA COCH PLPPR4 SYT5	3.30e-05	182	148	6	d41ff834b8fc1d0e23cac7ae261de5f72874e462
ToppCell	facs-Brain_Non-Myeloid-Cortex-3m-Neuronal-SPN_Neuron_STR\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FRAS1 SYT6 HPCA COCH PLPPR4 SYT5	3.30e-05	182	148	6	6cde859edfe7607bd7ada89d20258413d06f4207
ToppCell	RA-13._Vascular_Smooth_Muscle\|World / Chamber and Cluster_Paper	A2M FAT3 DGKG SORT1 NHS PRKD1	3.41e-05	183	148	6	cae2ee08f985a6f005b4b8e959e465350315156a
ToppCell	Mid-temporal_gyrus_(MTG)-Non-neuronal-Macroglial-Oligo-OPC-OPC_L1-6_MYT1\|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	FMO3 DGKG ZNF462 ZFHX4 VCAN PLCE1	3.62e-05	185	148	6	2e1766f1a972fecd670daaaf7eb2d3a404f121e7
ToppCell	Mid-temporal_gyrus_(MTG)-Non-neuronal-Macroglial-Oligo-OPC\|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	FMO3 DGKG ZNF462 ZFHX4 VCAN PLCE1	3.62e-05	185	148	6	7aaa8335b40927e3e8fdcede807cd521fc213a0d
ToppCell	10x3'2.3-week_14-16-Mesenchymal_myocytic-stroma-myofibroblast\|week_14-16 / cell types per 3 fetal stages;per 3',per 5'	A2M FAT3 PCDHB14 SYT6 ZFHX4 PARVA	3.96e-05	188	148	6	116ca07ee4413dcc0e9e5ac99bfee6ed7b7847c6
ToppCell	facs-Brain_Non-Myeloid-Striatum-3m-Neuronal-medium_spiny_neuron\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SYT6 HPCA PTCHD1 COCH PLPPR4 SYT5	4.08e-05	189	148	6	3e8e30160a8d6f531ff743cb5918c9e79481f1bd
ToppCell	facs-Brain_Non-Myeloid-Striatum-3m-Neuronal-SPN_Neuron_STR\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SYT6 HPCA PTCHD1 COCH PLPPR4 SYT5	4.08e-05	189	148	6	851f8144aed5c7f80302911cd6b03f14bde7b56d
ToppCell	facs-Brain_Non-Myeloid-Striatum-3m-Neuronal\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SYT6 HPCA PTCHD1 COCH PLPPR4 SYT5	4.20e-05	190	148	6	1c5cf933ce71fed5638b9ef31eb81f6c2b6dadbc
ToppCell	human_hepatoblastoma-Tumor_cells\|World / Sample and Cell Type and Tumor Cluster (all cells)	FRAS1 TCERG1 VCAN AFDN PRKD1 RERE	4.45e-05	192	148	6	916fbec1c7ab7969bda711886ac88e877e30c280
ToppCell	renal_cortex_nuclei\|World / Celltypes from Cells and Nuclei per compartment and clinical group	FRAS1 SVIL NHS RERE FKBP5 EXOC4	4.45e-05	192	148	6	e8cc4d08fcfceeab75a02558817e4ccd7dbafe3a
ToppCell	facs-Brain_Non-Myeloid-Cortex-3m-Neuronal\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FRAS1 FAT3 HPCA KCNB1 PLPPR4 SYT5	4.85e-05	195	148	6	ffbab350e67d9c4b66c0ab84550daec8b8139a27
ToppCell	Control\|World / Condition, Lineage and Cell class	PPARG FFAR4 TFRC SORT1 SVIL ADGRE1	4.99e-05	196	148	6	2565f567c5274d1689e11600a2cb9e6770b65f74
ToppCell	Striatum-Neuronal-Excitatory\|Striatum / BrainAtlas - Mouse McCarroll V32	PCSK2 HPCA PTCHD1 PLPPR4 SYT5 PRKCG	4.99e-05	196	148	6	67400193ba469cf4d939e94f5ed94995e384bc07
ToppCell	BAL-Severe-Myeloid-TRAM-TRAM2\|Severe / Location, Disease Group, Cell group, Cell class (2021.03.09)	PPARG FFAR4 TFRC SORT1 VCAN SVIL	5.14e-05	197	148	6	d8ef5cb88dd66e112cb94217b9ad5cd70164f1d0
ToppCell	BAL-Severe-Myeloid-TRAM-TRAM2\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	PPARG FFAR4 TFRC SORT1 VCAN SVIL	5.14e-05	197	148	6	33f2fe101ae5744eea3915add37e60aa398bb97f
ToppCell	BAL-Severe-Myeloid-TRAM-TRAM2-\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	PPARG FFAR4 TFRC SORT1 VCAN SVIL	5.14e-05	197	148	6	5e9a3932ae5147a3d73dc70f1545926a692930ed
ToppCell	Severe_COVID-19-Myeloid-TRAM2\|Severe_COVID-19 / Disease group,lineage and cell class （2021.01.30）	PPARG FFAR4 TFRC SORT1 VCAN SVIL	5.14e-05	197	148	6	8a126cfe1529f3d75a806aa492743314a8a43ef9
ToppCell	BAL-Severe-Myeloid-TRAM-TRAM2-\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)	PPARG FFAR4 TFRC SORT1 VCAN SVIL	5.14e-05	197	148	6	9262785807faeb32417fad7ef202405053e453e2
ToppCell	Sepsis-URO\|Sepsis / Disease, condition lineage and cell class	PPARG COCH VCAN AGFG1 UPP1 FKBP5	5.43e-05	199	148	6	8e6dac82d1d0e759cd567f9c95b70cb4801d7caf
ToppCell	COVID-19-kidney-Epithelial_Doublet\|kidney / Disease (COVID-19 only), tissue and cell type	PPDPFL EYS KCNB1 C12orf42 ALAS2	5.92e-05	124	148	5	d6f59ddb9b9df02b5201f23fa5fb78f3fd891ee9
ToppCell	metastatic_Brain-T/NK_cells-CD8_low_T\|T/NK_cells / Location, Cell class and cell subclass	FRAS1 SYT6 PHOSPHO2 KCNB1 ZNF433	9.82e-05	138	148	5	b2ab273f3e62f169b3b9cb82342e6617af99f582
ToppCell	LPS-IL1RA-Endothelial-Mes-Like-Gen_Cap\|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	GRB14 ZNF619 EYS ZFHX4 SACS	1.24e-04	145	148	5	90ca38c02325c5c637c32efdef634b54cc3cd105
ToppCell	E18.5-samps-Mesenchymal-Myofibroblast-MyoFB-1\|E18.5-samps / Age Group, Lineage, Cell class and subclass	DNAH10 PIP5KL1 SYT5 MGAT5B RSPH10B	1.24e-04	145	148	5	ac41c6c02b7d78162b86222983688f54d04ac47d
ToppCell	Frontal_cortex-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)\|Frontal_cortex / BrainAtlas - Mouse McCarroll V32	SYT2 PPARG PIP5KL1 NHS TACR1	1.24e-04	145	148	5	8b13b576fd2e6e33ccb146860a91a53cee0cdd4d
ToppCell	Striatum-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)-Inhibitory_Neuron.Gad1Gad2.Chodl_(Low-threshold_spiking_interneuron,_Npy+/Sst+)--\|Striatum / BrainAtlas - Mouse McCarroll V32	HDGFL1 SLC6A16 GABRQ TECTA	1.26e-04	77	148	4	7bb18406d404c51ee938cc577c155dc51868ddb9
ToppCell	Striatum-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)-Inhibitory_Neuron.Gad1Gad2.Chodl_(Low-threshold_spiking_interneuron,_Npy+/Sst+)\|Striatum / BrainAtlas - Mouse McCarroll V32	HDGFL1 SLC6A16 GABRQ TECTA	1.26e-04	77	148	4	ac311740424ff75b478b3c19fa0fae93776eb54e
ToppCell	Striatum-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)-Inhibitory_Neuron.Gad1Gad2.Chodl_(Low-threshold_spiking_interneuron,_Npy+/Sst+)-\|Striatum / BrainAtlas - Mouse McCarroll V32	HDGFL1 SLC6A16 GABRQ TECTA	1.26e-04	77	148	4	9f2dbf922acb905d636427a766a217c0db9671d2
ToppCell	Hippocampus-Neuronal-Excitatory-eN1(Slc17a7)-eN1_2\|Hippocampus / BrainAtlas - Mouse McCarroll V32	PRSS35 FAT3 SORT1 HPCA PRKCG	1.32e-04	147	148	5	8f725ff8fb4ced5db2643e80669d3f7945b820ab
Disease	primary ovarian insufficiency (implicated_via_orthology)	USP17L21 USP17L4 USP17L2 USP17L12 USP17L1 USP17L20 USP17L11 USP17L24 USP17L5 USP17L10 USP17L19 USP17L18 USP17L17 USP17L6P USP17L3 USP17L22 USP17L15	4.82e-28	46	148	17	DOID:5426 (implicated_via_orthology)
Disease	congenital heart disease (implicated_via_orthology)	USP17L21 USP17L4 USP17L2 USP17L12 USP17L1 USP17L20 USP17L11 USP17L24 USP17L5 USP17L10 USP17L19 USP17L18 USP17L17 USP17L6P USP17L3 USP17L22 USP17L15	1.49e-24	69	148	17	DOID:1682 (implicated_via_orthology)
Disease	attention deficit hyperactivity disorder (implicated_via_orthology)	GIT1 PTCHD1 TACR1 ADGRE1	1.13e-05	28	148	4	DOID:1094 (implicated_via_orthology)
Disease	migraine disorder, Headache	NEMP1 MYO1H ZNF462 TJP2 PLCE1	7.45e-05	86	148	5	HP_0002315, MONDO_0005277
Disease	sideroblastic anemia (is_implicated_in)	HSCB ALAS2	7.47e-05	3	148	2	DOID:8955 (is_implicated_in)
Disease	sideroblastic anemia (implicated_via_orthology)	HSCB ALAS2	1.49e-04	4	148	2	DOID:8955 (implicated_via_orthology)
Disease	congenital myasthenic syndrome 7 (implicated_via_orthology)	SYT2 SYT5	1.49e-04	4	148	2	DOID:0110659 (implicated_via_orthology)
Disease	iron deficiency anemia (is_marker_for)	PON1 TFRC	1.49e-04	4	148	2	DOID:11758 (is_marker_for)
Disease	response to platinum based chemotherapy, cytotoxicity measurement	FRAS1 EYS	2.47e-04	5	148	2	EFO_0004647, EFO_0006952
Disease	neuromuscular junction disease (implicated_via_orthology)	SYT2 SYT5	2.47e-04	5	148	2	DOID:439 (implicated_via_orthology)
Disease	LDL cholesterol change measurement	APOB PKD1L3	5.16e-04	7	148	2	EFO_0007804
Disease	aspartate aminotransferase measurement, serum alanine aminotransferase measurement, low density lipoprotein triglyceride measurement, body fat percentage, high density lipoprotein cholesterol measurement, sex hormone-binding globulin measurement	DNAH10 PPARG ZZEF1 EDEM3 RPTOR POC1B RERE PLCE1	5.23e-04	364	148	8	EFO_0004612, EFO_0004696, EFO_0004735, EFO_0004736, EFO_0007800, EFO_0009946
Disease	Diabetes Mellitus	PON1 PPARG NR1I2	5.51e-04	32	148	3	C0011849
Disease	free cholesterol in large HDL measurement	MYO1H PON1 APOB PPARG	6.82e-04	79	148	4	EFO_0022157
Disease	benign neoplasm (implicated_via_orthology)	LATS1 LATS2	6.86e-04	8	148	2	DOID:0060072 (implicated_via_orthology)
Disease	visceral adipose tissue measurement	DNAH10 DGKG PPARG PKD1L3 ZZEF1 RPTOR SYT14 POC1B C12orf42	7.50e-04	481	148	9	EFO_0004765
Disease	Cardiovascular Diseases	PON1 APOB SORT1	7.82e-04	36	148	3	C0007222
Disease	body fat percentage	DNAH10 PPARG ZZEF1 TFRC EDEM3 RPTOR POC1B RERE PLCE1	8.30e-04	488	148	9	EFO_0007800
Disease	age at menarche	PCSK2 NEMP1 MYO1H KDM3B WDR25 ZNF462 ZFHX4 RPTOR PRKD1 RERE	8.64e-04	594	148	10	EFO_0004703
Disease	pancreatitis (implicated_via_orthology)	PPARG TACR1	8.79e-04	9	148	2	DOID:4989 (implicated_via_orthology)
Disease	phospholipids:total lipids ratio, high density lipoprotein cholesterol measurement	MYO1H PON1 APOB PKD1L3 FFAR4 AZIN1 TACR1	9.44e-04	307	148	7	EFO_0004612, EFO_0020946
Disease	non-high density lipoprotein cholesterol measurement	DNAH10 MYO1H GRB14 APOB PPARG NR1I2 BRCA2 POC1B AGFG1 FKBP5 PLCE1	9.76e-04	713	148	11	EFO_0005689
Disease	Metabolic Diseases	PON1 PPARG	1.10e-03	10	148	2	C0025517
Disease	abdominal obesity-metabolic syndrome (implicated_via_orthology)	PPARG GUCY2C	1.10e-03	10	148	2	DOID:0060611 (implicated_via_orthology)
Disease	beta thalassemia (is_marker_for)	PON1 APOB	1.33e-03	11	148	2	DOID:12241 (is_marker_for)
Disease	waist-hip ratio, sexual dimorphism	PPARG TACR1	1.33e-03	11	148	2	EFO_0004343, EFO_0005951
Disease	kidney cancer (implicated_via_orthology)	LATS1 LATS2	1.33e-03	11	148	2	DOID:263 (implicated_via_orthology)
Disease	mean fractional anisotropy measurement	ZZEF1 COCH VCAN PICK1	1.36e-03	95	148	4	EFO_0008399
Disease	high density lipoprotein particle size measurement	DNAH10 MYO1H PON1 APOB PPARG	1.70e-03	170	148	5	EFO_0008592
Disease	glutaroyl carnitine measurement	PPDPFL TACR1	1.88e-03	13	148	2	EFO_0021005
Disease	Hyperlipoproteinemia Type IIb	PON1 APOB	1.88e-03	13	148	2	C1704417
Disease	developmental disorder of mental health (implicated_via_orthology)	GABRR2 GABRQ PLXNB2	1.92e-03	49	148	3	DOID:0060037 (implicated_via_orthology)
Disease	cholesteryl ester measurement	DNAH10 PON1 GRB14 APOB PPARG EYS	1.94e-03	257	148	6	EFO_0010351
Disease	lifestyle measurement, depressive symptom measurement	RGMB PLPPR4 SERPINA13P EXOC4	1.96e-03	105	148	4	EFO_0007006, EFO_0010724
Disease	chylomicron measurement, very low density lipoprotein cholesterol measurement	DNAH10 MYO1H APOB PPARG	2.03e-03	106	148	4	EFO_0008317, EFO_0008596
Disease	cancer (implicated_via_orthology)	PIP5K1C LATS1 LATS2 BRCA2 PARVA CDK2	2.39e-03	268	148	6	DOID:162 (implicated_via_orthology)
Disease	breast cancer (is_marker_for)	KDM3B TFRC KSR1 PLCG1 CDK2	2.46e-03	185	148	5	DOID:1612 (is_marker_for)
Disease	Carcinoma, Granular Cell	PPARG NR1I2 PRKD1 PLCE1	2.82e-03	116	148	4	C0205644
Disease	Adenocarcinoma, Tubular	PPARG NR1I2 PRKD1 PLCE1	2.82e-03	116	148	4	C0205645
Disease	Adenocarcinoma, Oxyphilic	PPARG NR1I2 PRKD1 PLCE1	2.82e-03	116	148	4	C0205642
Disease	Carcinoma, Cribriform	PPARG NR1I2 PRKD1 PLCE1	2.82e-03	116	148	4	C0205643
Disease	Adenocarcinoma, Basal Cell	PPARG NR1I2 PRKD1 PLCE1	2.82e-03	116	148	4	C0205641
Disease	Adenocarcinoma	PPARG NR1I2 PRKD1 PLCE1	2.82e-03	116	148	4	C0001418
Disease	optic cup area measurement	FAT3 RERE PLCE1	2.82e-03	56	148	3	EFO_0006940
Disease	ovarian cancer (is_implicated_in)	APOB TFRC BRCA2	2.82e-03	56	148	3	DOID:2394 (is_implicated_in)
Disease	free cholesterol to total lipids in large HDL percentage	PON1 APOB PPARG	2.82e-03	56	148	3	EFO_0022279
Disease	Hyperlipoproteinemia Type IIa	PON1 APOB	2.86e-03	16	148	2	C0745103
Disease	Barrett Epithelium	PPARG NR1I2	2.86e-03	16	148	2	C1258085
Disease	congenital myasthenic syndrome (implicated_via_orthology)	SYT2 SYT5	2.86e-03	16	148	2	DOID:3635 (implicated_via_orthology)
Disease	Barrett Esophagus	PPARG NR1I2	2.86e-03	16	148	2	C0004763
Disease	Colorectal Carcinoma	PCSK2 ARFGEF1 APOB PPARG TFRC SACS GUCY2C MCM3AP PRKD1 EXOC4	2.94e-03	702	148	10	C0009402
Disease	obsessive-compulsive disorder, attention deficit hyperactivity disorder, Tourette syndrome, unipolar depression, bipolar disorder, autism spectrum disorder, schizophrenia, anorexia nervosa	KDM3B PPP1R13B KCNB1 RPTOR RERE	3.44e-03	200	148	5	EFO_0003756, EFO_0003761, EFO_0003888, EFO_0004242, EFO_0004895, MONDO_0004985, MONDO_0005090, MONDO_0005351
Disease	free cholesterol in HDL measurement	MYO1H GRB14 APOB	3.60e-03	61	148	3	EFO_0022264
Disease	Tourette syndrome, schizophrenia	DNAH10 RERE	3.63e-03	18	148	2	EFO_0004895, MONDO_0005090
Disease	Hypercholesterolemia, Familial	PON1 APOB	3.63e-03	18	148	2	C0020445
Disease	free cholesterol in very large HDL measurement	PON1 APOB PPARG	3.77e-03	62	148	3	EFO_0022273
Disease	autoimmune thyroid disease	PPARG C12orf42 RERE FKBP5	3.79e-03	126	148	4	EFO_0006812
Disease	cerebral infarction (is_marker_for)	A2M APOB	4.04e-03	19	148	2	DOID:3526 (is_marker_for)
Disease	cortical thickness	A2M EXD1 FAT3 SYT2 BTBD1 ZNF462 COCH BAZ1A VCAN RERE PICK1 EXOC4 PLCE1	4.08e-03	1113	148	13	EFO_0004840
Disease	serum homoarginine measurement	GRB14 WDR25	4.47e-03	20	148	2	EFO_0005421
Disease	total lipids in very large HDL measurement	PON1 APOB PPARG	4.49e-03	66	148	3	EFO_0022312
Disease	phospholipids in very large HDL measurement	PON1 APOB PPARG	4.49e-03	66	148	3	EFO_0022298
Disease	aggressive behaviour measurement, ADHD symptom measurement	MYO1H RPTOR POC1B	4.88e-03	68	148	3	EFO_0007826, EFO_0007860
Disease	Metabolic Syndrome X	PON1 NR1I2	4.93e-03	21	148	2	C0524620

Protein segments in the cluster

Peptide	Gene	Start	Entry
FGASHVFKFVDPSQD	AFDN	491	P55196
SQTFNHFFPEEKFET	FAM200B	516	P0CF97
RFFSDKETFHDIAQV	ADPGK	131	Q9BRR6
DVFHLTVPSKFTFEE	VCAN	251	P13611
ADSFHEPSAFNDFQR	AZIN1	386	O14977
TLVFEKHFPATIDSF	ARFGEF1	1306	Q9Y6D6
KPFSHLTVARKNFTF	B3GALT1	36	Q9Y5Z6
SEEGIFTVFPAHKFR	CACHD1	191	Q5VU97
RAAQEFKHDSFVPCS	GIT1	661	Q9Y2X7
SRFTHSEKFTFHLEP	CCDC22	291	O60826
VKFFLRHEDSPTENS	PPP1R13B	76	Q96KQ4
SFVKVDSHFRQGIPF	A2M	351	P01023
AQLARFSEEKFHFSD	BAZ1A	931	Q9NRL2
LNSHGLFDPEQKTFF	POLM	456	Q9NP87
ITTPKFAHAFRNLTF	GUCY2C	346	P25092
ASKFAEHVFRTFDTN	HPCA	61	P84074
FKSFFHSEPVLSNVR	PPDPFL	56	Q8WWR9
FSFTIRDSPAHFVNA	MEIOB	51	Q8N635
HEEFQKRSPSLFLCF	RSPH10B	506	P0C881
HEEFQKRSPSLFLCF	RSPH10B2	506	B2RC85
SFSKRFFSEHVPCNG	FBXO21	116	O94952
KFDSSHDRNEPFVFS	FKBP5	66	Q13451
SATFEDFQIRPHALF	PRKD1	136	Q15139
SKSKASFFLSHDQRF	PIP5KL1	136	Q5T9C9
FKTFVSSVNKHPDFA	FMO3	106	P31513
FSFAGLPESVKFHFT	FRAS1	1556	Q86XX4
SALHRFSTKAFNPSE	EYS	1511	Q5T1H1
EGKFQAFLDVSHFTP	HSPB2	71	Q16082
DNSVFHVSNLEFPFR	RNGTT	316	O60942
FFFGTHETAFLSPKR	HDGFL1	41	Q5TGJ6
AHPFFKTIDFSSDLR	LATS1	1006	O95835
DLKAHPFFSAIDFSS	LATS2	966	Q9NRM7
PFFSAIDFSSDIRKQ	LATS2	971	Q9NRM7
KFHFEFSSAVPEVVL	GABRQ	31	Q9UN88
KHNFLPEAFTTDFRV	EDEM3	381	Q9BZQ6
RIDKAPSFTSQDFHG	EXD1	361	Q8NHP7
QFHPAVRNSSEVKFA	MCM3AP	826	O60318
THGFSSFKFIPNTDD	CANT1	341	Q8WVQ1
FFNTPEKSVVSLFHD	CLCN7	466	P51798
AHREKLELAASFSFF	CPSF1	61	Q10570
HEFFRGKPTSREVFS	MGAT5B	566	Q3V5L5
NRTRFPFFSDVKGDH	FFAR4	21	Q5NUL3
FAFRTPKLSHDANET	PLXNB2	721	O15031
SHPFVKKAFRFSAGS	FAM157A	111	C9JC47
KENAFNISAFAHAAP	KSR1	521	Q8IVT5
PSFVFRTFDEFQELH	PIK3C2A	1456	O00443
SQKPISSFADFERHF	KIF22	211	Q14807
SSFADFERHFLPASR	KIF22	216	Q14807
DSAVSHFFSLPFKKS	PEX26	241	Q7Z412
QSPKRFADFVEGSSH	NEMP1	381	O14524
ASKFAEHVFRTFDTN	HPCAL1	61	P37235
HSFVKKAFRFSASPG	FAM157C	116	P0CG43
VEKVEHSPFSSFASQ	KDM3B	641	Q7LBC6
ENFDKFFTRAAPALT	PRKCG	641	P05129
SEFKAHTAPVRSVDF	POC1B	96	Q8TC44
TFDTTFSHFKNFRLP	NR1I2	161	O75469
AASFHDIFDKVFTNP	PHOSPHO2	111	Q8TCD6
PFAQHFSEASVASKD	ALAS2	176	P22557
FFHASEDIRKTFEIN	PCDHB14	281	Q9Y5E9
SPVRKNLFHFDESTT	RGPD3	1276	A6NKT7
FLAFSQKPRHETSDH	DGKG	76	P49619
FLEDESSSFHKRQFP	FUCA2	191	Q9BTY2
RPKNSLFKFESSSHA	EXOC4	436	Q96A65
FLLKAEPLAFTFSHD	APOB	1931	P04114
RSPEKHTAIAFNFEA	KCNB1	736	Q14721
FSASPKEGHFQETFN	BRCA2	3146	P51587
HETPAASKTVFFFFS	BTBD1	446	Q9H0C5
LDRETSPAFHFKVAA	FAT3	2771	Q8TDW7
SFTRKHFPFFRTAPE	FOXR1	201	Q6PIV2
SVKTGHPRFFNQLFS	CSAD	81	Q9Y600
IKSFPLHFDENSFFA	ERO1A	351	Q96HE7
SKEPRHLQFFSEFGN	GRB14	271	Q14449
AEEFNPESVFFSKIH	CCDC168	2716	Q8NDH2
SAKAALAHPFFQDVT	CDK2	276	P24941
PKESHAFFTREFTGL	COCH	516	O43405
QPVFTELFKFHTEAS	DNAH10	321	Q8IVF4
ELFKFHTEASDNVRF	DNAH10	326	Q8IVF4
PHSRSETFAFLKRFG	SACS	4066	Q9NZJ4
PDVFFVHSKRSFTHD	GABRR2	136	P28476
RKALEVFPEFAAAHS	OGT	351	O15294
VHPDFFSQRSQTEKD	HSCB	101	Q8IWL3
HRKTLNPAFNETFTF	SYT2	196	Q8N9I0
RQTLNPHFGETFAFK	SYT5	166	O00445
HRKTLNPTFDENFHF	SYT6	286	Q5T7P8
TSRHNFPALFGDVKF	UPP1	41	Q16831
FGDPHLRTFKDNFQT	RGMB	166	Q6NW40
SDFAKNFVQTDLPFH	SORT1	201	Q99523
CPVFTETFKFNHVES	SYT14	321	Q8NB59
DAHFKAFFQSEDSPS	RNF38	46	Q9H0F5
ITPLQDTFSFFRKHT	SLC6A16	521	Q9GZN6
SPARFQFTEEDLHFV	PRDM14	191	Q9GZV8
KFDVSSFNPHGISTF	PON1	106	P27169
SFQSEHSAFDRVPSK	SVIL	341	O95425
EFKDRHFLTFNSTRS	NHS	276	Q6T4R5
RFEPVHFVASSSKDE	NKRF	56	O15226
QAAKTFLSHFEDFPD	PLCE1	291	Q9P212
SFLKAPQFSHFQEDI	PTCHD1	616	Q96NR3
NLTPAHHFQDFRFKT	PIP5K1C	121	O60331
TTFFLNANDGKFDHP	NBEA	2396	Q8NFP9
KFDHPDRTFSSVARS	NBEA	2406	Q8NFP9
KFHNFFPIAAVFASI	TACR1	106	P25103
HSHSFDIKPFTTVDF	PPARG	56	P37231
NHLTFFASDFFVVPR	PKD1L3	666	Q7Z443
ALPREKEEFASAHFS	TELO2	46	Q9Y4R8
SRAHVAFPDFFRTST	SI	1356	P14410
NISHFSDIFAAREFK	RERE	246	Q9P2R6
HSFFLTPDSFEQKVL	PARVA	311	Q9NVD7
KFDTTFESARPTQTH	SIRT6	81	Q8N6T7
TKFPIVNAELSFFGH	TFRC	286	P02786
TAFRHSPFFAEQLTA	RPTOR	401	Q8N122
HKDDPSSFRFSETFS	SEC23A	561	Q15436
NERFFKDHQAPLTTS	ADGRE1	491	Q14246
NFAHFDNFPKSSSAD	AGFG1	281	P52594
FSPSHKTTRFGTLFE	C12orf40	211	Q86WS4
FSESPKFRSLHFLNF	C12orf42	71	Q96LP6
SSLPFFSVEAKNEHR	TECTA	356	O75443
KSFPSQHATLAAFAA	PLPPR4	246	Q7Z2D5
HFSKLTSSRPDAAFA	USP17L3	16	A6NCW0
IFQCDPSAKVFHTFS	ZNF100	176	Q8IYN0
DDKFLFSLTSPSIHF	ZFHX4	2816	Q86UP3
SFFIRSHFECEKETP	TJP2	606	Q9UDY2
DSAVHSPFTKRQAFT	UBAP2L	411	Q14157
HFSKLTSSRPDAAFA	USP17L4	16	A6NCW7
DPAKRRHNFTLAFST	SMTNL1	431	A8MU46
FNPRATFSEFAAKHA	TCERG1	741	O14776
RTFHLTSPAFEADAK	PRSS35	41	Q8N3Z0
PQFDEHFIFQVSSKT	SYT15B	261	X6R8R1
HFSKLTSSRPDAAFA	USP17L18	16	D6R9N7
HFSKLTSSRPDAAFA	USP17L5	16	A8MUK1
HFSKLTSSRPDAAFA	USP17L21	16	D6R901
HSRQDAGTPKFFLTD	PLCG1	611	P19174
ELDFHFPKFSISRTC	SERPINA13P	286	Q6UXR4
HFSKLTSSRPDAAFA	USP17L19	16	D6RCP7
HFSKLTSSRPDAAFA	USP17L1	16	Q7RTZ2
AFSFPSSFRKHERIH	ZNF709	316	Q8N972
VSFRHLDLSFNDFKA	TLR6	121	Q9Y2C9
FDNFFLHSKPEDTDT	ZNF84	161	P51523
HFSKLTSSRPDAAFA	USP17L12	16	C9JPN9
HFSKLTSSRPDAAFA	USP17L24	16	Q0WX57
KAGPRLQFLFHSDSS	ZZEF1	1166	O43149
FSDHGAALNTEKRFP	ZNF462	2401	Q96JM2
RFTSHATFNSEKLPE	ZNF821	186	O75541
HFSKLTSSRPDAAFA	USP17L6P	16	Q6QN14
RNFPKSSFHAQSESE	WDR25	141	Q64LD2
HFSKLTSSRPDAAFA	USP17L22	16	D6RA61
VDATPEFQRFHFTLK	TIGD7	491	Q6NT04
PAASEAFVKFADAHR	PICK1	201	Q9NRD5
HFSKLTSSRPDAAFA	USP17L15	16	C9J2P7
HFSKLTSSRPDAAFA	USP17L17	16	D6RBQ6
AHFFQDLAFPGKSSL	ZNF619	536	Q8N2I2
GKPFSNFSFFQIHER	ZNF433	456	Q8N7K0
AFVSKSHPEFSSNRQ	USP13	431	Q92995
HFSKLTSSRPDAAFA	USP17L23	16	D6RBM5
RFSVSFAKHPTNGFE	PPIP5K1	1071	Q6PFW1
HFSKLTSSRPDAAFA	USP17L2	16	Q6R6M4
HFSKLTSSRPDAAFA	USP17L20	16	D6RJB6
HFSKLTSSRPDAAFA	USP17L10	16	C9JJH3
HFSKLTSSRPDAAFA	USP17L11	16	C9JVI0
KFLDPGFSSHQAVAR	NAALADL1	556	Q9UQQ1
RTLFATEDAFEFSKH	MYO1H	691	Q8N1T3
VFASAERPVFTNHFL	PCSK2	21	P16519