Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionmetalloendopeptidase activity

ADAMTS12 ADAMTS7 ADAMTS9

1.12e-04120163GO:0004222
GeneOntologyMolecularFunctionmetallopeptidase activity

ADAMTS12 ADAMTS7 ADAMTS9

5.03e-04200163GO:0008237
GeneOntologyBiologicalProcessextracellular matrix organization

ADAMTS12 ADAMTS7 ADAMTS9 FKTN ADAMTSL4

7.35e-06377165GO:0030198
GeneOntologyBiologicalProcessextracellular structure organization

ADAMTS12 ADAMTS7 ADAMTS9 FKTN ADAMTSL4

7.45e-06378165GO:0043062
GeneOntologyBiologicalProcessexternal encapsulating structure organization

ADAMTS12 ADAMTS7 ADAMTS9 FKTN ADAMTSL4

7.54e-06379165GO:0045229
GeneOntologyBiologicalProcessnegative regulation of chondrocyte differentiation

ADAMTS12 ADAMTS7

1.96e-0427162GO:0032331
GeneOntologyBiologicalProcessossification involved in bone maturation

ADAMTS12 ADAMTS7

2.42e-0430162GO:0043931
GeneOntologyBiologicalProcessbone maturation

ADAMTS12 ADAMTS7

2.94e-0433162GO:0070977
GeneOntologyBiologicalProcessnegative regulation of cartilage development

ADAMTS12 ADAMTS7

3.50e-0436162GO:0061037
GeneOntologyBiologicalProcessanimal organ maturation

ADAMTS12 ADAMTS7

3.70e-0437162GO:0048799
GeneOntologyBiologicalProcesspigment cell differentiation

ADAMTS9 ADAMTSL4

4.33e-0440162GO:0050931
GeneOntologyBiologicalProcessdevelopmental pigmentation

ADAMTS9 ADAMTSL4

9.09e-0458162GO:0048066
GeneOntologyBiologicalProcessregulation of chondrocyte differentiation

ADAMTS12 ADAMTS7

9.41e-0459162GO:0032330
GeneOntologyBiologicalProcesssocial behavior

KCNQ2 NRXN3

1.47e-0374162GO:0035176
GeneOntologyBiologicalProcesscollagen fibril organization

ADAMTS12 ADAMTS7

1.55e-0376162GO:0030199
GeneOntologyBiologicalProcessbiological process involved in intraspecies interaction between organisms

KCNQ2 NRXN3

1.55e-0376162GO:0051703
GeneOntologyBiologicalProcessregulation of cartilage development

ADAMTS12 ADAMTS7

1.76e-0381162GO:0061035
GeneOntologyCellularComponentcell surface

CIITA ADAMTS7 UMODL1 ADAMTS9 ULBP1 KCNQ2 UNC5C

8.80e-061111167GO:0009986
GeneOntologyCellularComponentextracellular matrix

ADAMTS12 ADAMTS7 ADAMTS9 ADAMTSL4

1.29e-03656164GO:0031012
GeneOntologyCellularComponentexternal encapsulating structure

ADAMTS12 ADAMTS7 ADAMTS9 ADAMTSL4

1.31e-03658164GO:0030312
DomainTSP_1

ADAMTS12 ADAMTS7 ADAMTS9 ADAMTSL4 UNC5C

1.09e-0963155PF00090
DomainTSP1_rpt

ADAMTS12 ADAMTS7 ADAMTS9 ADAMTSL4 UNC5C

1.28e-0965155IPR000884
DomainTSP1

ADAMTS12 ADAMTS7 ADAMTS9 ADAMTSL4 UNC5C

1.28e-0965155PS50092
DomainTSP1

ADAMTS12 ADAMTS7 ADAMTS9 ADAMTSL4 UNC5C

1.28e-0965155SM00209
DomainADAM_spacer1

ADAMTS12 ADAMTS7 ADAMTS9 ADAMTSL4

2.36e-0923154IPR010294
DomainADAM_spacer1

ADAMTS12 ADAMTS7 ADAMTS9 ADAMTSL4

2.36e-0923154PF05986
DomainPLAC

ADAMTS12 ADAMTS7 ADAMTSL4

4.03e-0719153IPR010909
DomainPLAC

ADAMTS12 ADAMTS7 ADAMTSL4

4.03e-0719153PS50900
DomainPeptidase_M12B_ADAM-TS

ADAMTS12 ADAMTS7 ADAMTS9

8.40e-0724153IPR013273
DomainPep_M12B_propep

ADAMTS12 ADAMTS7 ADAMTS9

3.76e-0639153PF01562
DomainPeptidase_M12B_N

ADAMTS12 ADAMTS7 ADAMTS9

3.76e-0639153IPR002870
DomainDISINTEGRIN_1

ADAMTS12 ADAMTS7 ADAMTS9

4.07e-0640153PS00427
DomainReprolysin

ADAMTS12 ADAMTS7 ADAMTS9

4.07e-0640153PF01421
DomainADAM_MEPRO

ADAMTS12 ADAMTS7 ADAMTS9

4.07e-0640153PS50215
DomainDISINTEGRIN_2

ADAMTS12 ADAMTS7 ADAMTS9

4.07e-0640153PS50214
DomainPeptidase_M12B

ADAMTS12 ADAMTS7 ADAMTS9

4.07e-0640153IPR001590
DomainCYSTEINE_SWITCH

ADAMTS12 ADAMTS7 ADAMTS9

4.39e-0641153PS00546
DomainDisintegrin_dom

ADAMTS12 ADAMTS7 ADAMTS9

4.39e-0641153IPR001762
DomainPept_M10_metallopeptidase

ADAMTS12 ADAMTS7 ADAMTS9

5.07e-0643153IPR001818
Domain-

ADAMTS12 ADAMTS7 ADAMTS9

3.44e-05811533.40.390.10
DomainMetalloPept_cat_dom

ADAMTS12 ADAMTS7 ADAMTS9

3.44e-0581153IPR024079
DomainZINC_PROTEASE

ADAMTS12 ADAMTS7 ADAMTS9

6.09e-0598153PS00142
DomainEGF

UMODL1 PGAP6 NRXN3

8.00e-04235153SM00181
DomainEGF_3

UMODL1 PGAP6 NRXN3

8.00e-04235153PS50026
DomainEGF-like_dom

UMODL1 PGAP6 NRXN3

9.46e-04249153IPR000742
DomainEGF_1

UMODL1 PGAP6 NRXN3

1.01e-03255153PS00022
DomainEGF-like_CS

UMODL1 PGAP6 NRXN3

1.08e-03261153IPR013032
DomainEGF_2

UMODL1 PGAP6 NRXN3

1.13e-03265153PS01186
DomainASX_HYDROXYL

UMODL1 NRXN3

2.85e-03100152PS00010
DomainEGF-type_Asp/Asn_hydroxyl_site

UMODL1 NRXN3

3.19e-03106152IPR000152
PathwayREACTOME_O_GLYCOSYLATION_OF_TSR_DOMAIN_CONTAINING_PROTEINS

ADAMTS12 ADAMTS7 ADAMTS9 ADAMTSL4

3.51e-0839134M27417
PathwayREACTOME_O_GLYCOSYLATION_OF_TSR_DOMAIN_CONTAINING_PROTEINS

ADAMTS12 ADAMTS7 ADAMTS9 ADAMTSL4

3.51e-0839134MM15165
PathwayREACTOME_DISEASES_ASSOCIATED_WITH_O_GLYCOSYLATION_OF_PROTEINS

ADAMTS12 ADAMTS7 ADAMTS9 ADAMTSL4

3.43e-0768134M27303
PathwayREACTOME_O_LINKED_GLYCOSYLATION

ADAMTS12 ADAMTS7 ADAMTS9 ADAMTSL4

2.29e-06109134MM15164
PathwayREACTOME_O_LINKED_GLYCOSYLATION

ADAMTS12 ADAMTS7 ADAMTS9 ADAMTSL4

2.46e-06111134M27416
PathwayREACTOME_DISEASES_OF_GLYCOSYLATION

ADAMTS12 ADAMTS7 ADAMTS9 ADAMTSL4

6.76e-06143134M27275
PathwayREACTOME_DISEASES_OF_METABOLISM

ADAMTS12 ADAMTS7 ADAMTS9 ADAMTSL4

6.09e-05250134M27554
PathwayREACTOME_POST_TRANSLATIONAL_PROTEIN_MODIFICATION

APOL3 ADAMTS12 ADAMTS7 ADAMTS9 ADAMTSL4

6.04e-031389135MM15307
Pubmed

ADAMTS: a novel family of extracellular matrix proteases.

ADAMTS12 ADAMTS7 ADAMTS9

1.39e-081018311167130
Pubmed

Insights on ADAMTS proteases and ADAMTS-like proteins from mammalian genetics.

ADAMTS12 ADAMTS7 ADAMTS9

2.55e-081218325770910
Pubmed

O-fucosylation of thrombospondin type 1 repeats restricts epithelial to mesenchymal transition (EMT) and maintains epiblast pluripotency during mouse gastrulation.

ADAMTS12 ADAMTS7 ADAMTS9 ADAMTSL4

5.96e-087518420637190
Pubmed

The role of ADAMTS-7 and ADAMTS-12 in the pathogenesis of arthritis.

ADAMTS12 ADAMTS7

2.53e-07218219098927
Pubmed

Negative effects of ADAMTS-7 and ADAMTS-12 on endplate cartilage differentiation.

ADAMTS12 ADAMTS7

2.53e-07218222247065
Pubmed

Inhibition of ADAMTS-7 and ADAMTS-12 degradation of cartilage oligomeric matrix protein by alpha-2-macroglobulin.

ADAMTS12 ADAMTS7

1.52e-06418218485748
Pubmed

Genome-Wide Analysis in Brazilians Reveals Highly Differentiated Native American Genome Regions.

CIITA ADAMTS9

5.30e-06718228100790
Pubmed

The metalloproteinase-proteoglycans ADAMTS7 and ADAMTS12 provide an innate, tendon-specific protective mechanism against heterotopic ossification.

ADAMTS12 ADAMTS7

4.30e-051918229618652
Pubmed

The splicing regulator Rbfox2 is required for both cerebellar development and mature motor function.

KCNQ2 NRXN3

1.32e-043318222357600
Cytoband21q22.3

UMODL1 ZNF295-AS1

1.15e-0312818221q22.3
CytobandEnsembl 112 genes in cytogenetic band chr21q22

UMODL1 ZNF295-AS1

9.43e-03377182chr21q22
CytobandEnsembl 112 genes in cytogenetic band chr20q13

KCNQ2 MIR1-1HG

1.17e-02422182chr20q13
CytobandEnsembl 112 genes in cytogenetic band chr16p13

CIITA PGAP6

1.19e-02426182chr16p13
GeneFamilyADAM metallopeptidases with thrombospondin type 1 motif

ADAMTS12 ADAMTS7 ADAMTS9

8.23e-08199350
CoexpressionNABA_ECM_REGULATORS

ADAMTS12 ADAMTS7 ADAMTS9 ADAMTSL4

1.44e-05238174M3468
CoexpressionNABA_ECM_REGULATORS

ADAMTS12 ADAMTS7 ADAMTS9 ADAMTSL4

1.53e-05242174MM17062
CoexpressionKRAS.600_UP.V1_DN

APOL3 CIITA ADAMTS9 NRXN3

2.68e-05279174M2880
ToppCell3'_v3-bone_marrow-Lymphocytic_B-Pro-B|bone_marrow / Manually curated celltypes from each tissue

CIITA UMODL1 KCNQ2

2.68e-05156173b093dbba6662e4fffc8aa577587b77f64ac44b56
ToppCellAdult-Mesenchymal-vascular_smooth_muscle_cell-D122|Adult / Lineage, Cell type, age group and donor

ADAMTS12 ADAMTS9 UNC5C

2.89e-05160173fd14dfeb7021a4b7299371854dc8fc1fd66c8dae
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

UNC5C NRXN3 MIR1-1HG

3.78e-05175173d52794426f2703a80e91ae0a8ff2d8e0ce4aa4a8
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell-|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

UNC5C NRXN3 MIR1-1HG

3.78e-05175173454f03e6109d65f5db08dbb41ecc19ffb6bbc4e0
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

UMODL1 NRXN3 ZNF295-AS1

3.78e-051751731d8da48236549c01381f777ce5b2937f9f86acc2
ToppCellrenal_papilla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-high_collagen-matrisome_fibroblast-|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

ADAMTS12 UNC5C ZNF295-AS1

4.11e-05180173fdbd7c22044d9328a1e06e2f9a4451529d1df767
ToppCellrenal_papilla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-high_collagen-matrisome_fibroblast|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

ADAMTS12 UNC5C ZNF295-AS1

4.11e-05180173280ff5c8f292be1b88120db5ff1788b750644856
ToppCellCOVID-19-Heart-Pericyte|COVID-19 / Disease (COVID-19 only), tissue and cell type

ADAMTS12 ADAMTS9 UNC5C

4.18e-0518117333cac65ed1ea5e7bd72250495df4f850b143d5aa
ToppCellLV-07._Pericyte|LV / Chamber and Cluster_Paper

ADAMTS12 ADAMTS9 UNC5C

4.46e-05185173acb38eba871ec72f2a8136a33b87d33b8c85465d
ToppCellRV-07._Pericyte|RV / Chamber and Cluster_Paper

ADAMTS12 ADAMTS9 UNC5C

4.53e-05186173c533b264fbe12bc35467486fc7fbde24ba968fe1
ToppCellhuman_hepatoblastoma-Hepatic_Stellate_cells|World / Sample and Cell Type and Tumor Cluster (all cells)

ADAMTS12 ADAMTS9 UNC5C

4.53e-05186173cb1fc4b9140666b43415e21c9b434dc9b144e9d0
ToppCellhuman_hepatoblastoma-Hepatic_Stellate_cells|human_hepatoblastoma / Sample and Cell Type and Tumor Cluster (all cells)

ADAMTS12 ADAMTS9 UNC5C

4.90e-0519117378c3c2fdb68c3407f2436f90e1e6a780bbf8b79e
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell-|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

UNC5C NRXN3 MIR1-1HG

4.98e-05192173bfab13793e54de2550ee171397f7ece0625cdb4a
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

UNC5C NRXN3 MIR1-1HG

4.98e-05192173b54b0d5b88139905521c8d5d58332e89c08d589c
ToppCelldroplet-Liver-LIVER-NPC-1m-Mesenchymal-hepatic_stellate_cell|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ADAMTS9 ADAMTSL4 NRXN3

5.13e-05194173415801a3dfacf05f2b603fb424df3d045190a812
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Mesenchymal-Fibroblast-Collagen-low_Matrisome-low_fibroblast|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

ADAMTS12 UNC5C NRXN3

5.13e-0519417390efdbd7f1c85fd7fd622b10340250b1d8fc1197
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Mesenchymal-Fibroblast-Collagen-low_Matrisome-low_fibroblast-|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

ADAMTS12 UNC5C NRXN3

5.13e-05194173df82cce5ebeb73740b02cf816c6df82253cfd566
ToppCelldroplet-Liver-LIVER-NPC-1m-Mesenchymal-hepatic_stellate_cell|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ADAMTS9 ADAMTSL4 NRXN3

5.13e-05194173256cb33ec90328f2704921fb0fe0fd9812e138b0
ToppCelldroplet-Liver-LIVER-NPC-1m-Mesenchymal|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ADAMTS9 ADAMTSL4 NRXN3

5.13e-051941737942bc83c1bdca687795b91aa232824d603f9b09
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Mesenchymal-Fibroblast-high_collagen-matrisome_fibroblast|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

ADAMTS12 UNC5C NRXN3

5.21e-051951734f70157d42a16ff0259bc24a62803c4df4285c44
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Mesenchymal-Fibroblast-high_collagen-matrisome_fibroblast-|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

ADAMTS12 UNC5C NRXN3

5.21e-05195173803f714d91f2d97ecbee8c15a5139fd9310f66c7
ToppCellASK428-Endothelial-Endothelium|ASK428 / Donor, Lineage and Cell class of Lung cells from Dropseq

APOL3 ADAMTS9 ULBP1

5.29e-05196173b1a81eddb91fb462360692b7b0a3ba4a947eac40
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Mesenchymal|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

ADAMTS12 UNC5C NRXN3

5.37e-0519717380e153790cef37b743e22a7370ff5b3a6abf147d
ToppCellwk_08-11-Mesenchymal-Fibroblast|wk_08-11 / Celltypes from embryonic and fetal-stage human lung

ADAMTS12 KCNQ2 UNC5C

5.62e-05200173482dfbbd8958b64c31568dccbffe3cc9589f876b
ToppCellFetal_brain-organoid_Tanaka_cellReport-GW16-Neuronal-Interneuron|GW16 / Sample Type, Dataset, Time_group, and Cell type.

ADAMTSL4 NRXN3

3.97e-04781728ad496ccbffb62a50f195c3789a95d8c80e2272d
ToppCellHippocampus-Endothelial-ENDOTHELIAL_TIP-Dcn_1-Dcn_1_2-Endothelial_Tip.Dcn.Rbp4_(Rbp4)|Hippocampus / BrainAtlas - Mouse McCarroll V32

ADAMTS12 ADAMTS7

7.17e-04105172cec0bdfe2bbd87c7e84671c1eeafad17aec1cdb2
ToppCellHippocampus-Endothelial-ENDOTHELIAL_TIP-Dcn_1-Dcn_1_2|Hippocampus / BrainAtlas - Mouse McCarroll V32

ADAMTS12 ADAMTS7

7.17e-04105172dc5f6d62945a699734a71b8ab1d4266db6fb2918
ToppCellHippocampus-Endothelial-ENDOTHELIAL_TIP-Dcn_1-Dcn_1_2-Endothelial_Tip.Dcn.Rbp4_(Rbp4)-|Hippocampus / BrainAtlas - Mouse McCarroll V32

ADAMTS12 ADAMTS7

7.17e-04105172c4b3f085c7e372e529d2c5d275faba403e830d48
ToppCellprimary_visual_cortex-Neuronal-GABAergic_neuron-Lamp5-Lamp5_Lhx6|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

ADAMTS7 UNC5C

8.89e-041171720602bbad908cb28c5093b74d717da5f2af577943
ToppCellCOVID-19-kidney-EC(Imm)|COVID-19 / Disease (COVID-19 only), tissue and cell type

ADAMTS7 ZNF295-AS1

8.89e-041171729f53d349af2da198dd2fa1d4bf15178979190ecb
ToppCellTCGA-Bone_and_Soft_Tissue-Primary_Tumor-Sarcoma-Desmoid_Tumor|TCGA-Bone_and_Soft_Tissue / Sample_Type by Project: Shred V9

ADAMTS12 ADAMTS9

9.19e-04119172d8fbea9ded96fcc3ebdfb4d28873c563427ce811
ToppCellTCGA-Bone_and_Soft_Tissue-Primary_Tumor-Sarcoma-Desmoid_Tumor-7|TCGA-Bone_and_Soft_Tissue / Sample_Type by Project: Shred V9

ADAMTS12 ADAMTS9

9.19e-041191729e38f13bf98b9ee44b178300e6f80fd08a006296
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell-Outer_Medullary_Collecting_Duct_Intercalated_Cell_Type_A|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

UMODL1 NRXN3

9.97e-041241721fec6663cea40017438ead397b3bf8b3cdb67e58
ToppCellTCGA-Bladder-Primary_Tumor-Urothelial_Carcinoma-Non-Papillary_Muscle_Invasive_Urothelial_Carcinoma-2|TCGA-Bladder / Sample_Type by Project: Shred V9

ADAMTS9 MIR1-1HG

9.97e-04124172ff08f74c3bc8e60679e0e21370095936a174c580
ToppCellTCGA-Stomach-Primary_Tumor-Stomach_Adenocarcinoma-Stomach_Adenocarcinoma_-_NOS-7|TCGA-Stomach / Sample_Type by Project: Shred V9

NRXN3 MIR1-1HG

1.05e-031271725e4d110cc6e68cd8fc7a4771a65e6f8cd83e7721
ToppCelldroplet-Fat-Gat-18m-Mesenchymal-nan|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ADAMTS12 FKTN

1.13e-031321724152529611eeacf0c547e2a134d5b98c45426b13
ToppCellLPS-IL1RA+antiTNF-Epithelial_alveolar-AT_1-Differentiating_AT2|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

FKTN NRXN3

1.15e-031331725bf5e654653e2c340891f51e3f2a30441b7b6b2b
ToppCellTCGA-Adrenal-Primary_Tumor-Pheochromocytoma-Pheochromocytoma-5|TCGA-Adrenal / Sample_Type by Project: Shred V9

KCNQ2 NRXN3

1.16e-03134172d4b175257c47916ed90cdb5c555c2b26530ce8d5
ToppCellTCGA-Stomach-Primary_Tumor-Stomach_Adenocarcinoma-Stomach_Adenocarcinoma_-_Diffuse-7|TCGA-Stomach / Sample_Type by Project: Shred V9

NRXN3 MIR1-1HG

1.18e-03135172451e90c154e26ae4f72269d6765e7ef51d67313a
ToppCellPCW_05-06-Mesenchymal-Mesenchymal_fibroblastic-mes_immature3_(17)|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung

FKTN UNC5C

1.34e-031441721c001a5a3bbe4ecbce8305f8b260e933033550dd
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast-Degenerative_Fibroblast|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

ADAMTS7 ZNF295-AS1

1.34e-03144172cf9f049ab6cd80521598124f057c2debdde24788
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast-Degenerative_Fibroblast-Degenerative_Fibroblast_104|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

ADAMTS7 ZNF295-AS1

1.34e-0314417241eaeca54b3c39de417597267cbdb1f195dd885a
ToppCellTracheal-NucSeq-Immune_Myeloid-Macrophage_other-Macro_interstitial|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

APOL3 CIITA

1.36e-03145172778655fffd73df101e656154a41b478a1b695116
ToppCellfacs-Marrow-T-cells-3m-Myeloid-granulocyte|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ADAMTS9 NRXN3

1.42e-03148172ba277c898678dd36f8dc1d681301c71901b89055
ToppCellfacs-Marrow-T-cells-3m-Myeloid-granulocyte|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ADAMTS9 NRXN3

1.42e-03148172b4632029ebd14969bda59a1bd1454eadb8efe563
ToppCellPND07-Immune-Immune_Myeloid-DC-cDC2|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

CIITA KCNQ2

1.43e-0314917232e0be7da42d26956683b21a1e7ae6915e4c16fb
ToppCellTCGA-Breast-Primary_Tumor-Breast_Carcinoma-Infiltrating_Ductal_and_Lobular_Carcinoma-6|TCGA-Breast / Sample_Type by Project: Shred V9

ADAMTS12 NRXN3

1.43e-031491723904f8ce9078de238600ceceee0116af52256a1c
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Myocytic_interstitial_cell-Myofibroblast|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

ADAMTS12 UNC5C

1.45e-031501727a9d6a7ff8000e9a061e1b586e4c258cc91a2a09
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Myocytic_interstitial_cell-Myofibroblast-|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

ADAMTS12 UNC5C

1.45e-03150172e5b843cb2bc847f6cab4cbec0a2a6a72fac50fee
ToppCellfacs-Brain_Myeloid-Cerebellum_-18m-Myeloid-macrophage|Brain_Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CIITA PGAP6

1.47e-031511723105b8c0c401faa92e1ab8223d435b21ed45c5b7
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell-Cortical_Collecting_Duct_Intercalated_Cell_Type_A|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

UMODL1 ZNF295-AS1

1.49e-031521729391b46a441cf031665df1d142e3f65e98675eeb
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Epithelial-Renal_corpuscle_epithelial_cell-glomerular_visceral_epithelial_cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

ADAMTS9 UNC5C

1.55e-03155172e7f49e2fdaf184fa6b4e685518004e7deff1316d
ToppCellPBMC-Mild-Myeloid-cDC-cDC-cDC_3|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

CIITA KLF15

1.55e-031551729a27558c457f05808af07190b7a5006b047f1d58
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Epithelial-Renal_corpuscle_epithelial_cell-glomerular_visceral_epithelial_cell-Podocyte|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

ADAMTS9 UNC5C

1.55e-031551725a872ca70ae8c30b57f45a6772d7bf565e0c2663
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Epithelial-Renal_corpuscle_epithelial_cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

ADAMTS9 UNC5C

1.55e-0315517290e629681a72baacc7981b82883866a487638dbc
ToppCellPBMC-Mild-Myeloid-cDC-cDC-cDC_3|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

CIITA KLF15

1.55e-03155172ab539c04f10276ae919d82b1c75f99a84eb695bf
ToppCellPND07-28-samps-Lymphocyte|PND07-28-samps / Age Group, Lineage, Cell class and subclass

CIITA ULBP1

1.59e-03157172105f2711d7bae3be36714954e103c61cf021f957
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell-Distal_Convoluted_Tubule_Cell_Type_2|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

ULBP1 UNC5C

1.61e-031581727960337d87afecf2692ab65e5991f052ceddfacc
ToppCellmild-Myeloid-CD14_Monocytes_3|Myeloid / Cohort 2 (Rhapsody WB + PBMC) with disease condition, lineage and cell classs

APOL3 ADAMTSL4

1.65e-03160172a83568cd8a0b05642bacd43a8ec443e5ce314c4d
ToppCellCOVID-19_Severe-Treg|World / disease group, cell group and cell class

ADAMTS7 KCNQ2

1.67e-03161172c6eade2c60c572d823e6e81b5e8d47078671e9b0
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast-Collagen-high_Fibroblast|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

ADAMTS12 ULBP1

1.69e-03162172b936f8040dcd4db621ccded19237af8df7d0ed6e
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Neural-neural_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

KCNQ2 NRXN3

1.69e-03162172d28b2ea1d2c8f3c6a107991573471b6d0c49c4ae
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast-Collagen-high_Fibroblast-|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

ADAMTS12 ULBP1

1.69e-031621725f009b231f21861afee9cc0c569082e1135f929c
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Neural-neural_cell-Schwann_Cell_/_Neural-|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

KCNQ2 NRXN3

1.69e-031621725bbd7130d4dad9035e73a439dda568195c136f31
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Neural-neural_cell-Schwann_Cell_/_Neural|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

KCNQ2 NRXN3

1.69e-03162172eed223e61c8162a2fe004ab4e09de5e037be7553
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Neural|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

KCNQ2 NRXN3

1.69e-03162172e35ddce830e20ebeac1a2c405293fc4a5323dd4a
ToppCell10x5'-Liver-Lymphocytic_Invariant-Inducer-like-ILC3|Liver / Manually curated celltypes from each tissue

UNC5C ZNF295-AS1

1.71e-031631727f61483eeb1fde21843c6391468e13cb0cc2a89f
ToppCellfrontal_cortex-Neuronal-GABAergic_neuron-Lamp5-Lamp5_Lsp1|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

ADAMTS7 UNC5C

1.71e-03163172bba830a302919c8b33f914a8839877fc21dd28a0
ToppCell3'-GW_trimst-1.5-LargeIntestine-Neuronal-neuron_precursor|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

KLF15 KCNQ2

1.71e-0316317299cf60dc87f7ce288553091bffcd85109a02bd8f
ToppCell3'-GW_trimst-1.5-LargeIntestine-Neuronal-neuron_precursor-Neuroblast|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

KLF15 KCNQ2

1.71e-03163172510c0af66e82c5a8cf8edd0547dae4018a87dbbf
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal--glomerular_mesenchymal_cell-Renin-positive_Juxtaglomerular_Granular_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

UNC5C NRXN3

1.73e-0316417243630a448f4369fa9e4e3eccdf3b9f29cec16c39
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal--glomerular_mesenchymal_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

UNC5C NRXN3

1.73e-0316417246208f18325976c89f572f6627aea0582142b92d
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

UNC5C NRXN3

1.73e-03164172108fbecb56d69a675d6ce6e826a873ae528f2fd7
ToppCellfacs-Marrow-B-cells-24m-Myeloid-granulocyte_monocyte_progenitor_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ADAMTS12 NRXN3

1.75e-031651726d315e0734079ad05336cc2c3f24d870c9105bc8
ToppCellfacs-Marrow-B-cells-24m-Myeloid-granulocyte_monocyte_progenitor_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ADAMTS12 NRXN3

1.75e-0316517284f5597b1bb75f42de9a224196bb8ac198bbe3bf
ToppCellnormal_Lymph_Node-Myeloid_cells-CD141+_DCs|Myeloid_cells / Location, Cell class and cell subclass

APOL3 CIITA

1.77e-031661726210a136efb99d70c2026b6454363f1bd2723558
ToppCellE18.5-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_vascular-Pericyte-Pericyte_prolif|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

ULBP1 ADAMTSL4

1.80e-03167172b0eb7a40491dd2432f5282f578ce569df86d21a7
ToppCelldroplet-Lung-LUNG-1m-Myeloid-dendritic_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CIITA ULBP1

1.80e-03167172e30e7ac8ea4399dc3c1d94fc6b857afc80a7a671
ToppCell356C-Fibroblasts-Fibroblast-H|356C / Donor, Lineage, Cell class and subclass (all cells)

ADAMTS12 UNC5C

1.82e-03168172838ce47d4958ba12047882f97925eddd02f081c7
ToppCellfacs-Brain_Non-Myeloid-Striatum-24m-Neuronal-medium_spiny_neuron|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CIITA KCNQ2

1.82e-03168172b96a48552f4236a95bbcdce2f1b05041086d7101
ToppCellTCGA-Lung-Primary_Tumor-Lung_Carcinoma-Lung_Squamous_Cell_Carcinoma-4|TCGA-Lung / Sample_Type by Project: Shred V9

ADAMTS12 UNC5C

1.82e-03168172aefea14b8b1c1b6a05f827effd22ba15274fddc9
ToppCellfacs-Brain_Non-Myeloid-Striatum-24m-Neuronal-SPN_Neuron_STR|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CIITA KCNQ2

1.82e-03168172b87fc63f9e35dfcfc46cb129ea569e73c5e018bb
ToppCell356C-Fibroblasts-Fibroblast-H-|356C / Donor, Lineage, Cell class and subclass (all cells)

ADAMTS12 UNC5C

1.82e-03168172b5d74500bdac0d680ce7eb7afa0b867b8d85e6a4
ToppCellLA-16._Neuronal|LA / Chamber and Cluster_Paper

ADAMTS9 NRXN3

1.82e-03168172c55bbfbde8bb954f1cb9af82007bdd1f8070fee3
ToppCellLA-16._Neuronal|World / Chamber and Cluster_Paper

ADAMTS9 NRXN3

1.82e-031681722fd1fd2a16ac1c5eb028f93cc3a2477c7747693e
ToppCellPrimary_Visual_cortex_(V1C)-Neuronal-Glutamatergic_Excit-Glut_C_(NP)|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

ADAMTS12 ADAMTS9

1.84e-03169172bddb28a8b9afbe4a68f082e82caf96a6666fc674
ToppCell3'-GW_trimst-1-LargeIntestine-Hematopoietic-B_cells-Pro-B|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

CIITA UMODL1

1.84e-031691727fd13b6e6041032697d36dd215f6b943d4675cf2
ToppCell3'-GW_trimst-2-LargeIntestine-Neuronal-Glial_immature-Glia_3_(BCAN+)|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

KCNQ2 NRXN3

1.84e-031691722456b3e7776e8a2214972be1b4d66a3ca5480ae0
ToppCellPrimary_Visual_cortex_(V1C)-Neuronal-Glutamatergic_Excit-Glut_C_(NP)-Glut_NP_L5/6_FEZF2|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

ADAMTS12 ADAMTS9

1.84e-031691725ce46bac8e767feec7ecdc61689de225c49bd3f7
ToppCellP15-Mesenchymal-mesenchymal_fibroblast-mesenchymal_progenitor_cell|P15 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

CIITA ADAMTS7

1.86e-03170172ba4ba66b624089ed50a9083176386c7941b4c7a3
ToppCell3'-GW_trimst-1-LargeIntestine-Hematopoietic-B_cells|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

CIITA UMODL1

1.86e-03170172e319ab46842d028898c09d6d8f056f896edb1558
ToppCell10x5'v1-week_17-19-Hematopoietic-HSC/MPP_and_pro-ELP|week_17-19 / cell types per 3 fetal stages;per 3',per 5'

ADAMTS7 UMODL1

1.86e-03170172a50e558d0b38100ccbdccb90647fe93e85bffd86
ToppCellCOVID-19_Severe-Treg|COVID-19_Severe / disease group, cell group and cell class

ADAMTS7 KCNQ2

1.86e-03170172d61269a51283125835884c4aa50623756c4fdda2
ToppCell10x3'2.3-week_12-13-Myeloid_DC-DC-DC1|week_12-13 / cell types per 3 fetal stages;per 3',per 5'

APOL3 CIITA

1.88e-0317117204346d4eb726875e3537e215ea081a0318ca4ddd
ToppCellControl-Fibroblasts-Pericytes|Control / group, cell type (main and fine annotations)

ADAMTS9 UNC5C

1.88e-03171172080003f698f867935c2bfc55d241d3650f45a0ab
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

ADAMTS12 UNC5C

1.88e-031711725d31fc9b60329d4ae3c77e4ca679359d9314397d
ToppCell3'-Distal_airway-Immune_Myeloid-Dendritic-conventional_dendritic_cell|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

APOL3 CIITA

1.88e-03171172173bb5318fdbaef6e695b6f9e3e0ff4a5432a1a4
ToppCell3'-Distal_airway-Immune_Myeloid-Dendritic-conventional_dendritic_cell-DC1_(conventional_dendritic_cell)|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

APOL3 CIITA

1.88e-031711721018d7bd378ce20bee56a77d5851b3538c55098c
ToppCell3'-Distal_airway-Immune_Myeloid-Dendritic-conventional_dendritic_cell-DC1_(conventional_dendritic_cell)-DC1_L.1.2.1.2|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

APOL3 CIITA

1.88e-031711726bda333bb751d7835a04f21ac959eea79f2516aa
ToppCellLV-13._Vascular_Smooth_Muscle|LV / Chamber and Cluster_Paper

ADAMTS9 UNC5C

1.88e-03171172e99ecae66530d1ae09330cee408c8f3950b87e67
Diseasealcohol dependence measurement

UNC5C NRXN3

4.56e-0455172EFO_0007835
Diseasepolychlorinated biphenyls measurement

UMODL1 ZNF295-AS1

6.36e-0465172EFO_0007042
Diseasesmoking cessation

ADAMTS7 KCNQ2 NRXN3

8.03e-04325173EFO_0004319
DiseaseSchizophrenia

ADAMTS12 KCNQ2 UNC5C NRXN3

1.39e-03883174C0036341
Diseasesmoking behavior, body mass index

ADAMTS7 NRXN3

2.25e-03123172EFO_0004318, EFO_0004340
Diseaseangina pectoris

ADAMTS7 UNC5C

2.32e-03125172EFO_0003913
Diseaset-tau measurement

ADAMTS12 NRXN3

2.36e-03126172EFO_0004760
Diseasetrauma exposure measurement

NRXN3 ZNF295-AS1

4.34e-03172172EFO_0010703
Diseasemortality

ADAMTS12 NRXN3

4.39e-03173172EFO_0004352

Protein segments in the cluster

PeptideGeneStartEntry
TSYVSCGGWIPWRRC

UMODL1

56

Q5DID0
RVGTYAVCWCSWNTG

nan

36

Q6ZRU5
YWEAGEWTSCSRSCG

ADAMTSL4

726

Q6UY14
KSYWAGAVSRAWACG

CIITA

426

P33076
NWSECSTTCGLGAYW

ADAMTS12

1321

P58397
CGAQPCLSWYTSSWR

ADAMTS7

1516

Q9UKP4
WAAGCCCRYRGWRGR

KCNQ2

146

O43526
GWNRFICDCTGTGYW

NRXN3

661

Q9Y4C0
ASPCSWERLLCYGWS

MIR1-1HG

101

Q9H1L0
RAGSTCAGWALWRCA

HRES1

191

P13985
YLYASCSCKAGWRGW

PGAP6

516

Q9HCN3
CNTGGWRYSAWTECS

ADAMTS9

996

Q9P2N4
GWGWEASCFACLIRS

APOL3

6

O95236
WLSSGTCLGWYRQCN

FKTN

296

O75072
SCALWSYCGRGWSRA

COQ5

6

Q5HYK3
FACTWPGCGWRFSRS

KLF15

351

Q9UIH9
GWSRAGWVDTHCLCY

ULBP1

21

Q9BZM6
TDLRSYGCFVCGWAW

ZNF295-AS1

116

Q8N0V1
WTEWSVCNSRCGRGY

UNC5C

266

O95185