Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
Domain	C/EBP_chordates	CEBPA CEBPD	1.46e-04	4	93	2	IPR016468
Domain	C/EBP	CEBPA CEBPD	2.43e-04	5	93	2	IPR031106
Domain	MYTH4	MYO7B MYO10	8.63e-04	9	93	2	PS51016
Domain	MyTH4_dom	MYO7B MYO10	8.63e-04	9	93	2	IPR000857
Domain	MyTH4	MYO7B MYO10	8.63e-04	9	93	2	PF00784
Domain	MyTH4	MYO7B MYO10	8.63e-04	9	93	2	SM00139
Domain	ALPHA_CA_2	PTPRG CA6	3.18e-03	17	93	2	PS51144
Domain	Carb_anhydrase	PTPRG CA6	3.18e-03	17	93	2	PF00194
Domain	Acyl_Trfase/lysoPLipase	PLA2G4B PLA2G6	3.18e-03	17	93	2	IPR016035
Domain	bZIP_2	CEBPA CEBPD	3.18e-03	17	93	2	PF07716
Domain	Carb_anhydrase	PTPRG CA6	3.18e-03	17	93	2	SM01057
Domain	-	PTPRG CA6	3.18e-03	17	93	2	3.10.200.10
Domain	Carbonic_anhydrase_a	PTPRG CA6	3.18e-03	17	93	2	IPR001148
Domain	ZZ	TADA2B CREBBP	3.56e-03	18	93	2	PF00569
Domain	ZF_ZZ_2	TADA2B CREBBP	3.56e-03	18	93	2	PS50135
Domain	ZF_ZZ_1	TADA2B CREBBP	3.56e-03	18	93	2	PS01357
Domain	-	NAA15 TCF25 TTC36 HELZ TTC9C	3.76e-03	207	93	5	1.25.40.10
Domain	Znf_ZZ	TADA2B CREBBP	3.97e-03	19	93	2	IPR000433
Domain	ZnF_ZZ	TADA2B CREBBP	3.97e-03	19	93	2	SM00291
Domain	ConA-like_dom	RANBP10 TRIM67 FAT3 MDGA1 RYR2	4.77e-03	219	93	5	IPR013320
Pubmed	CCAAT/enhancer-binding protein family members recruit the coactivator CREB-binding protein and trigger its phosphorylation.	CEBPA CEBPD CREBBP	7.63e-08	4	94	3	12857754
Pubmed	Intestinal maturation in mice lacking CCAAT/enhancer-binding protein alpha (C/EPBalpha).	CEBPA CEBPD APOA4	5.36e-06	13	94	3	9494081
Pubmed	Molecular Basis of Gene-Gene Interaction: Cyclic Cross-Regulation of Gene Expression and Post-GWAS Gene-Gene Interaction Involved in Atrial Fibrillation.	PITX2 ZFHX3	7.23e-06	2	94	2	26267381
Pubmed	Apolipoproteins A-IV and A-V are acute-phase proteins in mouse HDL.	APOA5 APOA4	7.23e-06	2	94	2	15306172
Pubmed	Next-generation sequencing of nine atrial fibrillation candidate genes identified novel de novo mutations in patients with extreme trait of atrial fibrillation.	PITX2 ZFHX3	7.23e-06	2	94	2	25391453
Pubmed	Transcription factor ZFHX3 regulates calcium influx in mammary epithelial cells in part via the TRPV6 calcium channel.	TRPV6 ZFHX3	7.23e-06	2	94	2	31519324
Pubmed	E3 ubiquitin ligase UBR5 promotes pancreatic cancer growth and aerobic glycolysis by downregulating FBP1 via destabilization of C/EBPα.	CEBPA UBR5	7.23e-06	2	94	2	33122826
Pubmed	Contribution of APOA5 gene variants to plasma triglyceride determination and to the response to both fat and glucose tolerance challenges.	APOA5 APOA4	7.23e-06	2	94	2	12697303
Pubmed	DNMT1-interacting RNAs block gene-specific DNA methylation.	CEBPA DNMT1	7.23e-06	2	94	2	24107992
Pubmed	PRISMA and BioID disclose a motifs-based interactome of the intrinsically disordered transcription factor C/EBPα.	NAA15 CEBPA CEBPD CLASP1 UBR5 NCF1 CPNE1 TTC9C CREBBP SNRPE HNRNPLL MNDA DNMT1	8.55e-06	1103	94	13	34189442
Pubmed	A genome wide association study identifies common variants associated with lipid levels in the Chinese population.	APOA5 APOA4 RYR2	1.26e-05	17	94	3	24386095
Pubmed	Prediction of the coding sequences of mouse homologues of KIAA gene: II. The complete nucleotide sequences of 400 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.	FEM1B CLASP1 UBR5 MYO10 TCF25 ARHGEF12 CHPF2 PUM1	1.52e-05	407	94	8	12693553
Pubmed	Genetic heritability of ischemic stroke and the contribution of previously reported candidate gene and genomewide associations.	PITX2 ZFHX3	2.16e-05	3	94	2	23042660
Pubmed	Subnuclear localization of C/EBP beta is regulated by growth hormone and dependent on MAPK.	CEBPA CEBPD	2.16e-05	3	94	2	12821655
Pubmed	Prognostic Value of Copine 1 in Patients With Renal Cell Carcinoma.	EPHA2 CPNE1	2.16e-05	3	94	2	34969745
Pubmed	The APOA5 Trp19 allele is associated with metabolic syndrome via its association with plasma triglycerides.	APOA5 APOA4	2.16e-05	3	94	2	18789138
Pubmed	Expression of the CCAAT/enhancer-binding proteins C/EBPalpha, C/EBPbeta and C/EBPdelta in breast cancer: correlations with clinicopathologic parameters and cell-cycle regulatory proteins.	CEBPA CEBPD	2.16e-05	3	94	2	12825852
Pubmed	GLUT4 repression in response to oxidative stress is associated with reciprocal alterations in C/EBP alpha and delta isoforms in 3T3-L1 adipocytes.	CEBPA CEBPD	2.16e-05	3	94	2	16754198
Pubmed	Impact of APOA5/A4/C3 genetic polymorphisms on lipid variables and cardiovascular disease risk in French men.	APOA5 APOA4	2.16e-05	3	94	2	16321685
Pubmed	Association of gene variants with lipid levels in response to fenofibrate is influenced by metabolic syndrome status.	APOA5 APOA4	2.16e-05	3	94	2	21324458
Pubmed	Ubinuclein, a novel nuclear protein interacting with cellular and viral transcription factors.	CEBPA PPL	2.16e-05	3	94	2	10725330
Pubmed	Regulated expression of three C/EBP isoforms during adipose conversion of 3T3-L1 cells.	CEBPA CEBPD	2.16e-05	3	94	2	1840554
Pubmed	The Role of DNMT1 and C/EBPα in the Regulation of CYP11A1 Expression During Syncytialization of Human Placental Trophoblasts.	CEBPA DNMT1	2.16e-05	3	94	2	38146648
Pubmed	Mechanisms of NSAID-induced gastrointestinal injury defined using mutant mice.	RAG2 FUT7	2.16e-05	3	94	2	10982764
Pubmed	Oncogenic steroid receptor coactivator-3 is a key regulator of the white adipogenic program.	CEBPA CEBPD	2.16e-05	3	94	2	17098861
Pubmed	Relative contribution of variation within the APOC3/A4/A5 gene cluster in determining plasma triglycerides.	APOA5 APOA4	2.16e-05	3	94	2	12417525
Pubmed	Regulation of mouse chondrocyte differentiation by CCAAT/enhancer-binding proteins.	CEBPA CEBPD	2.16e-05	3	94	2	25749148
Pubmed	CCAAT/enhancer binding protein alpha, beta and delta gene variants: associations with obesity related phenotypes in the Leeds Family Study.	CEBPA CEBPD	2.16e-05	3	94	2	20460359
Pubmed	Pref-1 in brown adipose tissue: specific involvement in brown adipocyte differentiation and regulatory role of C/EBPδ.	CEBPA CEBPD	2.16e-05	3	94	2	22324440
Pubmed	Transcriptional regulation of cyclooxygenase-2 in response to proteasome inhibitors involves reactive oxygen species-mediated signaling pathway and recruitment of CCAAT/enhancer-binding protein delta and CREB-binding protein.	CEBPD CREBBP	2.16e-05	3	94	2	16195339
Pubmed	Myc-Miz1 signaling promotes self-renewal of leukemia stem cells by repressing Cebpα and Cebpδ.	CEBPA CEBPD	2.16e-05	3	94	2	32040550
Pubmed	Apolipoprotein AIV gene variant S347 is associated with increased risk of coronary heart disease and lower plasma apolipoprotein AIV levels.	APOA5 APOA4	2.16e-05	3	94	2	12676816
Pubmed	Differential expression of three C/EBP isoforms in multiple tissues during the acute phase response.	CEBPA CEBPD	2.16e-05	3	94	2	1371993
Pubmed	The expression of intact and mutant human apoAI/CIII/AIV/AV gene cluster in transgenic mice.	APOA5 APOA4	4.32e-05	4	94	2	15649902
Pubmed	CAATT/enhancer-binding proteins alpha and delta interact with NKX2-1 to synergistically activate mouse secretoglobin 3A2 gene expression.	CEBPA CEBPD	4.32e-05	4	94	2	18632661
Pubmed	Effects of Polymorphisms in APOA4-APOA5-ZNF259-BUD13 Gene Cluster on Plasma Levels of Triglycerides and Risk of Coronary Heart Disease in a Chinese Han Population.	APOA5 APOA4	4.32e-05	4	94	2	26397108
Pubmed	Retinoblastoma protein positively regulates terminal adipocyte differentiation through direct interaction with C/EBPs.	CEBPA CEBPD	4.32e-05	4	94	2	8946919
Pubmed	Variants in ZFHX3 are associated with atrial fibrillation in individuals of European ancestry.	PITX2 ZFHX3	4.32e-05	4	94	2	19597492
Pubmed	CLASP1, astrin and Kif2b form a molecular switch that regulates kinetochore-microtubule dynamics to promote mitotic progression and fidelity.	KIF2B CLASP1	4.32e-05	4	94	2	20852589
Pubmed	Associations of the apolipoprotein A1/C3/A4/A5 gene cluster with triglyceride and HDL cholesterol levels in women with type 2 diabetes.	APOA5 APOA4	4.32e-05	4	94	2	16781717
Pubmed	C/EBP transcription factors regulate SREBP1c gene expression during adipogenesis.	CEBPA CEBPD	4.32e-05	4	94	2	19811452
Pubmed	C/EBP transcription factors mediate epicardial activation during heart development and injury.	CEBPA CEBPD	4.32e-05	4	94	2	23160954
Pubmed	Associations of polymorphisms in the apolipoprotein A1/C3/A4/A5 gene cluster with familial combined hyperlipidaemia in Hong Kong Chinese.	APOA5 APOA4	4.32e-05	4	94	2	19732897
Pubmed	T cell receptor (TCR) and transforming growth factor β (TGF-β) signaling converge on DNA (cytosine-5)-methyltransferase to control forkhead box protein 3 (foxp3) locus methylation and inducible regulatory T cell differentiation.	RAG2 DNMT1	4.32e-05	4	94	2	23687305
Pubmed	Mechanisms of liver-specific gene expression.	CEBPA CEBPD	4.32e-05	4	94	2	1638120
Pubmed	The APOA1/C3/A4/A5 cluster and markers of allostatic load in the Boston Puerto Rican Health Study.	APOA5 APOA4	4.32e-05	4	94	2	20674306
Pubmed	Effects of variations in the APOA1/C3/A4/A5 gene cluster on different parameters of postprandial lipid metabolism in healthy young men.	APOA5 APOA4	4.32e-05	4	94	2	19592705
Pubmed	T Cells Prevent Hemorrhagic Transformation in Ischemic Stroke by P-Selectin Binding.	RAG2 FUT7	4.32e-05	4	94	2	29903733
Pubmed	PD-1+ memory phenotype CD4+ T cells expressing C/EBPalpha underlie T cell immunodepression in senescence and leukemia.	RAG2 CEBPA	4.32e-05	4	94	2	19805226
Pubmed	Identifying functional non-coding variants in APOA5/A4/C3/A1 gene cluster associated with coronary heart disease.	APOA5 APOA4	4.32e-05	4	94	2	32437778
Pubmed	Antiadipogenic effect of carnosic acid, a natural compound present in Rosmarinus officinalis, is exerted through the C/EBPs and PPARγ pathways at the onset of the differentiation program.	CEBPA CEBPD	4.32e-05	4	94	2	23541989
Pubmed	Tissue-specific DNA methylation profiles regulate liver-specific expression of the APOA1/C3/A4/A5 cluster and can be manipulated with demethylating agents on intestinal cells.	APOA5 APOA4	4.32e-05	4	94	2	25463085
Pubmed	CD8+ T Cells Require ITK-Mediated TCR Signaling for Migration to the Intestine.	RAG2 ITK	4.32e-05	4	94	2	32034085
Pubmed	Pharmacogenetic association of the APOA1/C3/A4/A5 gene cluster and lipid responses to fenofibrate: the genetics of lipid-lowering drugs and diet network study.	APOA5 APOA4	4.32e-05	4	94	2	19057464
Pubmed	The apolipoprotein CIII enhancer regulates both extensive histone modification and intergenic transcription of human apolipoprotein AI/CIII/AIV genes but not apolipoprotein AV.	APOA5 APOA4	4.32e-05	4	94	2	18678879
Pubmed	Genetic association study of APOA1/C3/A4/A5 gene cluster and haplotypes on triglyceride and HDL cholesterol in a community-based population.	APOA5 APOA4	4.32e-05	4	94	2	17964293
Pubmed	Evidence for consistent intragenic and intergenic interactions between SNP effects in the APOA1/C3/A4/A5 gene cluster.	APOA5 APOA4	4.32e-05	4	94	2	16710093
Pubmed	'Default' generated neonatal regulatory T cells are hypomethylated at conserved non-coding sequence 2 and promote long-term cardiac allograft survival.	RAG2 DNMT1	4.32e-05	4	94	2	24944101
Pubmed	The effects of scale: variation in the APOA1/C3/A4/A5 gene cluster.	APOA5 APOA4	4.32e-05	4	94	2	15108119
Pubmed	Cellular and molecular requirements for the selection of in vitro-generated CD8 T cells reveal a role for Notch.	RAG2 ITK	4.32e-05	4	94	2	23851691
Pubmed	Identification of CCAAT/enhancer-binding proteins as exchange protein activated by cAMP-activated transcription factors that mediate the induction of the SOCS-3 gene.	CEBPA CEBPD	4.32e-05	4	94	2	18195020
Pubmed	Genetic variants on apolipoprotein gene cluster influence triglycerides with a risk of coronary artery disease among Indians.	APOA5 APOA4	4.32e-05	4	94	2	19701693
Pubmed	FUS-DDIT3 prevents the development of adipocytic precursors in liposarcoma by repressing PPARgamma and C/EBPalpha and activating eIF4E.	CEBPA CEBPD	4.32e-05	4	94	2	18596980
Pubmed	Polymorphisms in the APOA1/C3/A4/A5 gene cluster and cholesterol responsiveness to dietary change.	APOA5 APOA4	4.32e-05	4	94	2	17378725
Pubmed	Systematic bromodomain protein screens identify homologous recombination and R-loop suppression pathways involved in genome integrity.	DCDC1 EIF4ENIF1 UBR5 FAT3 PKP4 TADA2B TCF25 HELZ ZFHX3 CHPF2 CREBBP BRWD1	4.77e-05	1116	94	12	31753913
Pubmed	The RNA-mediated estrogen receptor α interactome of hormone-dependent human breast cancer cell nuclei.	EIF4ENIF1 ZKSCAN1 PCNX3 CLASP1 PKP4 TADA2B ARHGEF12 MRPS34 HELZ PHF14 ZFHX3 TASOR SNRPE HNRNPLL	4.89e-05	1497	94	14	31527615
Pubmed	Osteocyte transcriptome mapping identifies a molecular landscape controlling skeletal homeostasis and susceptibility to skeletal disease.	SKIDA1 DACT3 MTSS2	5.96e-05	28	94	3	33953184
Pubmed	Knockdown of macrophage migration inhibitory factor disrupts adipogenesis in 3T3-L1 cells.	CEBPA CEBPD	7.19e-05	5	94	2	18703634
Pubmed	A null mutation in human APOC3 confers a favorable plasma lipid profile and apparent cardioprotection.	APOA5 APOA4	7.19e-05	5	94	2	19074352
Pubmed	Astrocytic CCAAT/Enhancer-binding protein delta contributes to reactive oxygen species formation in neuroinflammation.	CEBPD NCF1	7.19e-05	5	94	2	29499563
Pubmed	CCAAT/enhancer-binding protein delta (C/EBPdelta) maintains amelogenin expression in the absence of C/EBPalpha in vivo.	CEBPA CEBPD	7.19e-05	5	94	2	17704518
Pubmed	Transforming growth factor-beta inhibits adipocyte differentiation by Smad3 interacting with CCAAT/enhancer-binding protein (C/EBP) and repressing C/EBP transactivation function.	CEBPA CEBPD	7.19e-05	5	94	2	12524424
Pubmed	Substrate binding allosterically relieves autoinhibition of the pseudokinase TRIB1.	CEBPA CEBPD	7.19e-05	5	94	2	30254053
Pubmed	RUNX1 is required in granulocyte-monocyte progenitors to attenuate inflammatory cytokine production by neutrophils.	RAG2 CEBPA	7.19e-05	5	94	2	37536952
Pubmed	CCAAT/enhancer binding protein isoforms expression in the colon of neonatal mice.	CEBPA CEBPD	7.19e-05	5	94	2	8563027
Pubmed	The C/EBP family of transcription factors in the liver and other organs.	CEBPA CEBPD	7.19e-05	5	94	2	10319019
Pubmed	APOE, CETP and LPL genes show strong association with lipid levels in Greek children.	APOA5 APOA4	1.08e-04	6	94	2	19403283
Pubmed	Regulation of the pro-B-cell-specific enhancer of the Id1 gene involves the C/EBP family of proteins.	CEBPA CEBPD	1.08e-04	6	94	2	9001238
Pubmed	Deubiquitinase DUBA is a post-translational brake on interleukin-17 production in T cells.	RAG2 UBR5	1.08e-04	6	94	2	25470037
Pubmed	Genetic risk factors for ischaemic stroke and its subtypes (the METASTROKE collaboration): a meta-analysis of genome-wide association studies.	PITX2 ZFHX3	1.08e-04	6	94	2	23041239
Pubmed	A genome-wide meta-analysis identifies 22 loci associated with eight hematological parameters in the HaemGen consortium.	HFE TAOK1 RNF145	1.08e-04	34	94	3	19820697
Pubmed	Neuromedin U programs eosinophils to promote mucosal immunity of the small intestine.	RAG2 EPX	1.50e-04	7	94	2	37708282
Pubmed	CCAAT/enhancer binding protein delta (C/EBPdelta, CEBPD)-mediated nuclear import of FANCD2 by IPO4 augments cellular response to DNA damage.	CEBPD UBR5	1.50e-04	7	94	2	20805509
Pubmed	Reciprocal roles of MSX2 in regulation of osteoblast and adipocyte differentiation.	CEBPA CEBPD	1.50e-04	7	94	2	15175325
Pubmed	Tails of unconventional myosins.	MYO7B MYO10	1.50e-04	7	94	2	11212352
Pubmed	CCAAT/enhancer binding protein alpha knock-in mice exhibit early liver glycogen storage and reduced susceptibility to hepatocellular carcinoma.	CEBPA CEBPD	1.50e-04	7	94	2	16288022
Pubmed	Maternal Transient Receptor Potential Vanilloid 6 (Trpv6) Is Involved In Offspring Bone Development.	CACNA1E TRPV6 RYR2	1.51e-04	38	94	3	30786075
Pubmed	Kelch Domain of Gigaxonin Interacts with Intermediate Filament Proteins Affected in Giant Axonal Neuropathy.	DCDC1 CLASP1 ARHGEF12 HELZ EPX	1.59e-04	187	94	5	26460568
Pubmed	A haplotype in the inducible T-cell tyrosine kinase is a risk factor for seasonal allergic rhinitis.	CD3D ITK	2.00e-04	8	94	2	19222422
Pubmed	An N-ethyl-N-nitrosourea screen for genes involved in variegation in the mouse.	TASOR DNMT1	2.00e-04	8	94	2	15890782
Pubmed	Mapping a locus for susceptibility to HIV-1-associated nephropathy to mouse chromosome 3.	APOA5 APOA4	2.00e-04	8	94	2	14983036
Pubmed	Essential requirement of CCAAT/enhancer binding proteins in embryogenesis.	CEBPA CEBPD	2.00e-04	8	94	2	15509779
Pubmed	Mammalian APE1 controls miRNA processing and its interactome is linked to cancer RNA metabolism.	ZBTB48 PKP4 PITX2 MIF4GD CPNE1 PRDM4 MTERF4 HNRNPLL DNMT1 BRWD1	2.03e-04	925	94	10	28986522
Pubmed	Functional proteomics mapping of a human signaling pathway.	PLEKHB2 ABRAXAS2 UBR5 PUM1 PRDM4 CREBBP PPL RYR2	2.05e-04	591	94	8	15231748
Pubmed	Protein interaction network of the mammalian Hippo pathway reveals mechanisms of kinase-phosphatase interactions.	ABRAXAS2 EIF4ENIF1 CLASP1 UBR5 PKP4 HELZ PUM1	2.13e-04	446	94	7	24255178
Pubmed	The effects of trichostatin A on mRNA expression of chromatin structure-, DNA methylation-, and development-related genes in cloned mouse blastocysts.	CREBBP DNMT1	2.57e-04	9	94	2	18241125
Pubmed	The role of Pitx2 and Pitx3 in muscle stem cells gives new insights into P38α MAP kinase and redox regulation of muscle regeneration.	RAG2 PITX2	2.57e-04	9	94	2	30106373
Pubmed	Thymic stromal lymphopoietin induces adipose loss through sebum hypersecretion.	RAG2 EPX	2.57e-04	9	94	2	34326208
Pubmed	AGPAT2 deficiency impairs adipogenic differentiation in primary cultured preadipocytes in a non-autophagy or apoptosis dependent mechanism.	CEBPA CEBPD	2.57e-04	9	94	2	26417690
Pubmed	Defective adipocyte differentiation in mice lacking the C/EBPbeta and/or C/EBPdelta gene.	CEBPA CEBPD	2.57e-04	9	94	2	9405372
Interaction	HNRNPLL interactions	CEBPA TRIM67 EIF4ENIF1 ZBTB48 UBR5 HELZ TASOR HNRNPLL	8.06e-07	163	92	8	int:HNRNPLL
Cytoband	11q23	CD3D APOA5 APOA4	5.65e-05	36	94	3	11q23
Cytoband	Ensembl 112 genes in cytogenetic band chr11q23	CD3D APOA5 ARHGEF12 TTC36 APOA4	9.37e-05	220	94	5	chr11q23
GeneFamily	Basic leucine zipper proteins\|CCAAT/enhancer binding proteins	CEBPA CEBPD	2.01e-04	6	67	2	1165
Drug	haloperidol; Down 200; 10uM; MCF7; HT_HG-U133A	RANBP10 CEBPA PKP4 ARHGEF12 ZFHX3 PPL BRF2 BRWD1	1.73e-06	199	94	8	6963_DN
Disease	meningitis	CACNA1E APOA5 APOA4	4.60e-06	11	91	3	MONDO_0021108
Disease	Antithrombotic agent use measurement	APOA5 PITX2 ZFHX3 APOA4	2.56e-05	55	91	4	EFO_0009925
Disease	semaphorin-6C measurement	APOA5 APOA4	2.82e-05	3	91	2	EFO_0803051
Disease	Rare dyslipidemia	APOA5 APOA4	2.82e-05	3	91	2	Orphanet_101953
Disease	Ischemic stroke, cardiac embolism	PITX2 ZFHX3	2.82e-05	3	91	2	EFO_1001493, HP_0002140
Disease	apolipoprotein A-IV measurement	APOA5 APOA4	9.35e-05	5	91	2	EFO_0007848
Disease	mean arterial pressure	HFE DCDC1 PCNX3 PKP4 ARHGEF12 ZFHX3 PPL DNMT1	1.57e-04	499	91	8	EFO_0006340
Disease	familial sick sinus syndrome	PITX2 ZFHX3	2.60e-04	8	91	2	MONDO_0012061
Disease	sick sinus syndrome	PITX2 ZFHX3	2.60e-04	8	91	2	MONDO_0001823
Disease	hematocrit	ABRAXAS2 FEM1B HFE RANBP10 CEBPA DCDC1 APOA5 SLC20A2 APOA4 EPX TASOR	2.81e-04	1011	91	11	EFO_0004348
Disease	apolipoprotein A-V measurement	APOA5 APOA4	3.34e-04	9	91	2	EFO_0801387
Disease	hyperlipidemia	APOA5 APOA4	3.34e-04	9	91	2	MONDO_0021187
Disease	diacylglycerol 34:3 measurement	APOA5 APOA4	5.08e-04	11	91	2	EFO_0020059
Disease	beta-endorphin measurement	APOA5 APOA4	6.08e-04	12	91	2	EFO_0008034
Disease	acute myeloid leukemia (implicated_via_orthology)	CEBPA CREBBP	6.08e-04	12	91	2	DOID:9119 (implicated_via_orthology)
Disease	sterol measurement	APOA5 APOA4	7.18e-04	13	91	2	EFO_0010231
Disease	severe combined immunodeficiency (is_implicated_in)	RAG2 CD3D	8.36e-04	14	91	2	DOID:627 (is_implicated_in)
Disease	HETE measurement	PLEKHB2 APOA5 APOA4	9.41e-04	62	91	3	EFO_0801166
Disease	Sclerocystic Ovaries	DDX54 DACT3 TRPV6 FUT7	1.05e-03	144	91	4	C1136382
Disease	Polycystic Ovary Syndrome	DDX54 DACT3 TRPV6 FUT7	1.05e-03	144	91	4	C0032460
Disease	diacylglycerol 36:2 measurement	APOA5 APOA4	1.10e-03	16	91	2	EFO_0010355
Disease	diacylglycerol 44:7 measurement	APOA5 APOA4	1.10e-03	16	91	2	EFO_0020069
Disease	proprotein convertase subtilisin/kexin type 7 measurement	APOA5 APOA4	1.24e-03	17	91	2	EFO_0008270
Disease	autism spectrum disorder (implicated_via_orthology)	NAA15 PKP4 TAOK1 CREBBP	1.28e-03	152	91	4	DOID:0060041 (implicated_via_orthology)
Disease	diacylglycerol 36:3 measurement	APOA5 APOA4	1.39e-03	18	91	2	EFO_0020062
Disease	Omenn Syndrome	RAG2 CD3D	1.55e-03	19	91	2	C2700553
Disease	Hypertriglyceridemia	APOA5 APOA4	1.55e-03	19	91	2	EFO_0004211
Disease	non-high density lipoprotein cholesterol measurement	HFE CEBPA APOA5 HELZ PLA2G6 EPX ECHDC2 BRWD1	1.63e-03	713	91	8	EFO_0005689
Disease	Severe Combined Immunodeficiency	RAG2 CD3D	1.72e-03	20	91	2	C0085110
Disease	cholesteryl ester 18:1 measurement	APOA5 APOA4	2.48e-03	24	91	2	EFO_0010344
Disease	diacylglycerol 34:1 measurement	APOA5 APOA4	2.48e-03	24	91	2	EFO_0010352
Disease	Head Neoplasms	CEBPA APOBEC3B	2.48e-03	24	91	2	C0018675
Disease	Upper Aerodigestive Tract Neoplasms	CEBPA APOBEC3B	2.48e-03	24	91	2	C0887900
Disease	Cancer of Head	CEBPA APOBEC3B	2.48e-03	24	91	2	C0751177
Disease	diacylglycerol 34:2 measurement	APOA5 APOA4	2.69e-03	25	91	2	EFO_0010353
Disease	Neck Neoplasms	CEBPA APOBEC3B	2.69e-03	25	91	2	C0027533
Disease	Cancer of Neck	CEBPA APOBEC3B	2.69e-03	25	91	2	C0746787
Disease	platelet measurement	APOA5 TAOK1 APOA4 RNF145 TASOR	2.95e-03	315	91	5	EFO_0005036

Protein segments in the cluster

Peptide	Gene	Start	Entry
PAREQNRRLQHQQLY	PKP4	1101	Q99569
YLRNNFRPQQRLHDR	PTPRG	301	P23470
LQREIQYIFPNASRQ	ABCA5	1546	Q8WWZ7
ALLRNDQVYQPLRDR	CD3D	141	P04234
NRRYNQRISLAIPNL	ABRAXAS2	151	Q15018
RRQQQIERELNGYRA	CACNA1E	371	Q15878
FQRQLRGAQYQPILR	DNMT1	1396	P26358
NFNNDPLVLRRRQTY	APOBEC3B	201	Q9UH17
NPQYREMLRRQLLQQ	CREBBP	2186	Q92793
VRQRLQAFRQDTYLQ	APOA5	281	Q6Q788
RSVNPYLQGQRLDNV	SCG5	181	P05408
RQSPINLQRTKVRYN	CA6	46	P23280
QLLQEDYNRTPAQRL	ARHGEF12	221	Q9NZN5
PYLIRRAQENRSVLQ	PRODH2	496	Q9UF12
NNIRPANLYRIRVDL	RAG2	226	P55895
SRRLQRLYPAVNQQE	RANBP10	36	Q6VN20
YARPTRLNVIRNDND	HNRNPLL	241	Q8WVV9
LQQRLEPYADQLRTQ	APOA4	131	P06727
DPVLNYRLSIRQLNQ	MDGA1	671	Q8NFP4
NPLIYSLRNNEVRNA	OR8D4	286	Q8NGM9
ANYARIRRQQGPQAT	DCDC1	1751	M0R2J8
IGQALYANREAARQR	TCTE1	466	Q5JU00
YANREAARQRALNPS	TCTE1	471	Q5JU00
NPRYQNQFAEIHRRA	MAGEB5	71	Q9BZ81
QALRRAQLQYVQRSE	GMIP	211	Q9P107
ICYRRQLERQLQQRQ	SLC43A2	536	Q8N370
TDDRRRRYNSQFNPQ	LENG1	236	Q96BZ8
YQRARALAQEILPQA	ECHDC2	221	Q86YB7
VADNAQQQYVRSRPA	DDX54	511	Q8TDD1
RANDINYQDQIPRTL	FEM1B	606	Q9UK73
QQQELVFLRNRNPER	PCNX3	1741	Q9H6A9
TIPRNSNIAQNYRRL	MTSS2	516	Q765P7
RRRQYENFINRNLEA	PPL	251	O60437
RNRTNYLGLLAINQR	EPX	326	P11678
YNQRQELRSNGEEPR	NEK5	436	Q6P3R8
QDAYRRNSVRFLQQR	NCF1	321	P14598
QERQLRARLYRQLAP	FUT7	181	Q11130
EKNRVVRQNPGERNY	MYO10	246	Q9HD67
PSQLQRYRQELAERA	PLA2G4B	376	P0C869
ARQNRAYLERDCPAQ	HFE	176	Q30201
QSRLLQYRQVQSRSP	HELZ	1601	P42694
PEAQARINARLQQYR	PHF14	531	O94880
TRYQLLQLRPAQRAS	NAA15	136	Q9BXJ9
FRNNRYPNLQLREIA	PUM1	836	Q14671
NVENQLQYARVQRDR	BECN2	231	A8MW95
RQEYRVQQALRLAQP	DACT3	36	Q96B18
RDRNFQLRQNLYLVG	GLYCTK	71	Q8IVS8
SPEYRQRRERNNIAV	CEBPD	191	P49716
NSNEYRVRRERNNIA	CEBPA	281	P49715
RRKNQRARQSPEDVY	EPHA2	561	P29317
QEFPYRRNLARVIVN	FAT3	1541	Q8TDW7
IEAVRRNNIYELNPN	BRWD1	976	Q9NSI6
PQEVRDFQRAQAARQ	BRF2	396	Q9HAW0
DNFIQRTKQRYNNPR	SEC22A	116	Q96IW7
PAQESNYRLLRRNNS	SLC20A2	371	Q08357
QQDVKNRRNPRLVPY	RYR2	1021	Q92736
YRRFQNAPREALAQT	CPNE1	486	Q99829
RARRALDVNTRNPNY	KIF2B	171	Q8N4N8
RRGLLNRLQQEYQAR	MIF4GD	76	A9UHW6
NRLQQEYQAREQLRA	MIF4GD	81	A9UHW6
RKARNREEQNLVAYP	PRDM4	491	Q9UKN5
DYQTNDPQELALRRN	ITK	181	Q08881
AQRQVDARRNVPQND	MNDA	196	P41218
LREQLNRPRDSQLYA	MRPS34	21	P82930
RRLQNECRGYNLQPD	RGL2	471	O15211
GQQPANQVIIRERYR	PLEKHB2	181	Q96CS7
RQRRKNIARDYNLVP	TADA2B	216	Q86TJ2
RQNQEYQVLLDVRAR	KRT34	376	O76011
NAYPEQRRARRQSQF	SSMEM1	121	Q8WWF3
NNYVQEPECRRNLVQ	MTERF4	61	Q7Z6M4
NNAFPQQRILREARK	SKIDA1	586	Q1XH10
PSYESRRQNQDRINK	SLITRK2	786	Q9H156
RTYRPNVELCRDQAQ	TEKT2	321	Q9UIF3
QAEEEANLLRRQRQY	TAOK1	596	Q7L7X3
FVDRLPQAVRNRVQA	NAP1L3	96	Q99457
QLQELEATFQRNRYP	PITX2	96	Q99697
ETVREPRFNQNVNLR	PLA2G6	606	O60733
NDPRVINRQRSSDYQ	TASOR	961	Q9UK61
PQVDRTRDGFRNRQQ	EIF4ENIF1	651	Q9NRA8
LEQLNRRYQPRLRFQ	CHPF2	411	Q9P2E5
REILRNQPARFKNYA	CLASP1	1371	Q7Z460
DRVENYNPRQRKLRN	ZBTB48	601	P10074
FQRNRLLEAIVQRYQ	TRIM67	176	Q6ZTA4
YQQQLQRVQERQRRL	SAPCD2	256	Q86UD0
RQDLNRQRIQRYAQA	TRPV6	676	Q9H1D0
NRQPKDANVRRYLQL	TTC9C	136	Q8N5M4
QPINLIFRYLQNRSR	SNRPE	16	P62304
NTEDQYKNPRRNLRC	ZNF563	51	Q8TA94
LPERASAYNNRAQAR	TTC36	81	A6NLP5
FQLDARRQQLVYRQQ	WDR4	271	P57081
RRQQLVYRQQLAFQH	WDR4	276	P57081
LARRNLSRDNRQENY	ZKSCAN1	246	P17029
SRDNNEYIARRPDNQ	RNF145	626	Q96MT1
ENRRKVLYQRAPRNI	TCF25	541	Q9BQ70
SSYIIRNPQQRRISQ	UBR5	1536	O95071
QLRVLRQYFDINNSP	ZFHX3	2156	Q15911
ARRNFQQRKANAPLV	MYO7B	871	Q6PIF6