Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	intracellularly cAMP-activated cation channel activity	HCN4 HCN1 HCN3	1.65e-05	10	105	3	GO:0005222
GeneOntologyMolecularFunction	intracellularly ligand-gated monoatomic ion channel activity	HCN4 HCN1 HCN3 RYR1	2.63e-05	33	105	4	GO:0005217
GeneOntologyMolecularFunction	NADH oxidase H202-forming activity	DUOX2 DUOX1	2.74e-05	2	105	2	GO:0106293
GeneOntologyMolecularFunction	intracellularly cyclic nucleotide-activated monoatomic cation channel activity	HCN4 HCN1 HCN3	3.89e-05	13	105	3	GO:0005221
GeneOntologyMolecularFunction	cyclic nucleotide-activated monoatomic ion channel activity	HCN4 HCN1 HCN3	3.89e-05	13	105	3	GO:0043855
GeneOntologyMolecularFunction	benzoate-CoA ligase activity	ACSM2A ACSM2B	8.19e-05	3	105	2	GO:0018858
GeneOntologyMolecularFunction	ligand-gated monoatomic cation channel activity	HCN4 HCN1 HCN3 ANO10 CHRNB1 RYR1	9.72e-05	140	105	6	GO:0099094
GeneOntologyMolecularFunction	decanoate-CoA ligase activity	ACSM2A ACSM2B	1.63e-04	4	105	2	GO:0102391
GeneOntologyMolecularFunction	NADPH oxidase H202-forming activity	DUOX2 DUOX1	2.71e-04	5	105	2	GO:0106294
GeneOntologyMolecularFunction	NADH binding	ALDH2 HSD17B8	2.71e-04	5	105	2	GO:0070404
GeneOntologyMolecularFunction	cAMP binding	HCN4 HCN1 HCN3	2.99e-04	25	105	3	GO:0030552
GeneOntologyMolecularFunction	voltage-gated sodium channel activity	HCN4 HCN1 HCN3	3.36e-04	26	105	3	GO:0005248
GeneOntologyMolecularFunction	four-way junction helicase activity	RECQL BLM	4.05e-04	6	105	2	GO:0009378
GeneOntologyMolecularFunction	ligand-gated monoatomic ion channel activity	HCN4 HCN1 HCN3 ANO10 CHRNB1 RYR1	5.49e-04	193	105	6	GO:0015276
GeneOntologyMolecularFunction	inositol-1,3,4,5-tetrakisphosphate 5-phosphatase activity	INPP5K INPP5J	5.65e-04	7	105	2	GO:0052659
GeneOntologyMolecularFunction	phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase activity	INPP5K INPP5J	5.65e-04	7	105	2	GO:0034485
GeneOntologyMolecularFunction	ligand-gated channel activity	HCN4 HCN1 HCN3 ANO10 CHRNB1 RYR1	6.12e-04	197	105	6	GO:0022834
GeneOntologyMolecularFunction	fatty-acyl-CoA synthase activity	ACSM2A ACSM2B	7.51e-04	8	105	2	GO:0004321
GeneOntologyMolecularFunction	inositol-polyphosphate 5-phosphatase activity	INPP5K INPP5J	7.51e-04	8	105	2	GO:0004445
GeneOntologyMolecularFunction	inositol-1,4,5-trisphosphate 5-phosphatase activity	INPP5K INPP5J	7.51e-04	8	105	2	GO:0052658
GeneOntologyMolecularFunction	inositol tetrakisphosphate phosphatase activity	INPP5K INPP5J	9.63e-04	9	105	2	GO:0052743
GeneOntologyMolecularFunction	cyclic nucleotide binding	HCN4 HCN1 HCN3	1.13e-03	39	105	3	GO:0030551
GeneOntologyMolecularFunction	phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity	INPP5K INPP5J	1.20e-03	10	105	2	GO:0004439
GeneOntologyMolecularFunction	medium-chain fatty acid-CoA ligase activity	ACSM2A ACSM2B	1.46e-03	11	105	2	GO:0031956
GeneOntologyMolecularFunction	DNA/DNA annealing activity	RECQL BLM	1.46e-03	11	105	2	GO:1990814
GeneOntologyMolecularFunction	phosphatidylinositol trisphosphate phosphatase activity	INPP5K INPP5J	1.46e-03	11	105	2	GO:0034594
GeneOntologyMolecularFunction	ATP-dependent activity	ABCA1 GPN1 RECQL MYO5C BLM MDN1 ATP6V1C2 ATP1A3 ACSM2A ACSM2B	1.47e-03	614	105	10	GO:0140657
GeneOntologyMolecularFunction	phosphatidylinositol-4,5-bisphosphate phosphatase activity	INPP5K INPP5J	1.75e-03	12	105	2	GO:0106019
GeneOntologyMolecularFunction	NAD(P)H oxidase H2O2-forming activity	DUOX2 DUOX1	1.75e-03	12	105	2	GO:0016174
GeneOntologyMolecularFunction	superoxide-generating NAD(P)H oxidase activity	DUOX2 DUOX1	1.75e-03	12	105	2	GO:0016175
GeneOntologyMolecularFunction	JUN kinase kinase kinase activity	MAP3K5 MAP3K10	1.75e-03	12	105	2	GO:0004706
GeneOntologyMolecularFunction	calcium ion binding	CAPN12 SPTAN1 DUOX2 CASQ2 RYR1 DUOX1 DST ADGRE5 UNC13C SCIN BAIAP3	1.95e-03	749	105	11	GO:0005509
GeneOntologyMolecularFunction	phosphatidylinositol phosphate 5-phosphatase activity	INPP5K INPP5J	2.06e-03	13	105	2	GO:0034595
GeneOntologyMolecularFunction	ligase activity	EPRS1 PFAS FARS2 ACSM2A ACSM2B	2.27e-03	174	105	5	GO:0016874
GeneOntologyMolecularFunction	inositol trisphosphate phosphatase activity	INPP5K INPP5J	2.39e-03	14	105	2	GO:0046030
GeneOntologyMolecularFunction	annealing activity	RECQL BLM	2.39e-03	14	105	2	GO:0140666
GeneOntologyMolecularFunction	zinc ion binding	LVRN UBR2 EPRS1 USP13 CPA5 PRICKLE1 POLE BLM HDAC10 BBOX1 L3MBTL3 RABIF	2.50e-03	891	105	12	GO:0008270
GeneOntologyMolecularFunction	sodium channel activity	HCN4 HCN1 HCN3	2.59e-03	52	105	3	GO:0005272
GeneOntologyMolecularFunction	GTPase binding	EPRS1 ABCA1 SPTBN1 UNC13D ALS2 TBC1D21 IPO11	2.94e-03	360	105	7	GO:0051020
GeneOntologyMolecularFunction	3'-5' DNA helicase activity	RECQL BLM	3.13e-03	16	105	2	GO:0043138
GeneOntologyMolecularFunction	1-phosphatidylinositol binding	SCIN ADAP2	3.54e-03	17	105	2	GO:0005545
GeneOntologyMolecularFunction	transmembrane receptor protein tyrosine phosphatase activity	PTPRD PTPRG	3.54e-03	17	105	2	GO:0005001
GeneOntologyMolecularFunction	transmembrane receptor protein phosphatase activity	PTPRD PTPRG	3.54e-03	17	105	2	GO:0019198
GeneOntologyMolecularFunction	phosphoric ester hydrolase activity	PDE8A INPP5K PPP1R3A PTPRD PTPRG PDE8B INPP5J	4.30e-03	386	105	7	GO:0042578
GeneOntologyMolecularFunction	estradiol 17-beta-dehydrogenase [NAD(P)+] activity	AKR1B10 HSD17B8	4.89e-03	20	105	2	GO:0004303
GeneOntologyMolecularFunction	inositol phosphate phosphatase activity	INPP5K INPP5J	4.89e-03	20	105	2	GO:0052745
GeneOntologyMolecularFunction	oxidoreductase activity, acting on NAD(P)H, oxygen as acceptor	DUOX2 DUOX1	4.89e-03	20	105	2	GO:0050664
GeneOntologyMolecularFunction	proteasome binding	USP13 UBD	4.89e-03	20	105	2	GO:0070628
GeneOntologyMolecularFunction	C-acyltransferase activity	ACSM2A ACSM2B	5.39e-03	21	105	2	GO:0016408
GeneOntologyMolecularFunction	3',5'-cyclic-AMP phosphodiesterase activity	PDE8A PDE8B	5.91e-03	22	105	2	GO:0004115
GeneOntologyBiologicalProcess	secretory granule localization	UNC13D MYO5C UNC13C CADPS2 BAIAP3	6.98e-07	34	103	5	GO:0032252
GeneOntologyBiologicalProcess	dense core granule exocytosis	UNC13D UNC13C CADPS2 BAIAP3	7.67e-07	15	103	4	GO:1990504
GeneOntologyBiologicalProcess	response to purine-containing compound	HCN4 HCN1 INPP5K HCN3 DUOX2 CASQ2 RYR1 DUOX1	1.85e-06	166	103	8	GO:0014074
GeneOntologyBiologicalProcess	response to organophosphorus	HCN4 HCN1 INPP5K HCN3 DUOX2 RYR1 DUOX1	7.22e-06	142	103	7	GO:0046683
GeneOntologyBiologicalProcess	response to cAMP	HCN4 HCN1 INPP5K HCN3 DUOX2 DUOX1	9.16e-06	97	103	6	GO:0051591
GeneOntologyBiologicalProcess	dense core granule localization	UNC13D UNC13C CADPS2 BAIAP3	1.09e-05	28	103	4	GO:0032253
GeneOntologyBiologicalProcess	cellular response to alkaloid	COMT CASQ2 RYR1 BLM	4.67e-05	40	103	4	GO:0071312
GeneOntologyBiologicalProcess	response to nitrogen compound	UBR2 EPRS1 USP13 ABCA1 COMT HCN4 HCN1 INPP5K HCN3 USP25 DUOX2 CASQ2 CHRNB1 RYR1 MAP3K5 BLM DUOX1 ATP1A3	5.43e-05	1272	103	18	GO:1901698
GeneOntologyBiologicalProcess	calcium-ion regulated exocytosis	UNC13D UNC13C CADPS2 SCIN BAIAP3	5.66e-05	82	103	5	GO:0017156
GeneOntologyBiologicalProcess	cuticle development	DUOX2 DUOX1	7.38e-05	3	103	2	GO:0042335
GeneOntologyBiologicalProcess	cellular response to nitrogen compound	UBR2 EPRS1 COMT HCN4 HCN1 INPP5K HCN3 CASQ2 CHRNB1 RYR1 MAP3K5 BLM ATP1A3	9.45e-05	752	103	13	GO:1901699
GeneOntologyBiologicalProcess	cellular response to cAMP	HCN4 HCN1 INPP5K HCN3	1.42e-04	53	103	4	GO:0071320
GeneOntologyBiologicalProcess	dense core granule priming	UNC13D UNC13C	1.47e-04	4	103	2	GO:0061789
GeneOntologyBiologicalProcess	renal water homeostasis	INPP5K HAS2 NFAT5	2.89e-04	26	103	3	GO:0003091
GeneOntologyBiologicalProcess	protein methylation	FAM86B1 FAM86B2 COMT PRMT9	3.33e-04	66	103	4	GO:0006479
GeneOntologyBiologicalProcess	protein alkylation	FAM86B1 FAM86B2 COMT PRMT9	3.33e-04	66	103	4	GO:0008213
GeneOntologyBiologicalProcess	fear response	COMT ALS2 PDE8B ATP1A3	3.33e-04	66	103	4	GO:0042596
GeneOntologyBiologicalProcess	membrane depolarization	HCN4 HCN1 HCN3 CHRNB1 ATP1A3	3.54e-04	121	103	5	GO:0051899
GeneOntologyCellularComponent	HCN channel complex	HCN4 HCN1 HCN3	4.91e-07	4	105	3	GO:0098855
GeneOntologyCellularComponent	cell leading edge	HCN1 INPP5K SPTBN1 DUOX2 ALS2 LDB2 DUOX1 DST ADGRE5 ARHGEF4 INPP5J	4.32e-05	500	105	11	GO:0031252
GeneOntologyCellularComponent	leading edge membrane	HCN1 INPP5K SPTBN1 ADGRE5 ARHGEF4 INPP5J	6.74e-04	210	105	6	GO:0031256
GeneOntologyCellularComponent	spectrin	SPTAN1 SPTBN1	8.79e-04	9	105	2	GO:0008091
GeneOntologyCellularComponent	junctional membrane complex	CASQ2 RYR1	8.79e-04	9	105	2	GO:0030314
GeneOntologyCellularComponent	Z disc	SPTAN1 OBSL1 CASQ2 RYR1 DST	9.95e-04	151	105	5	GO:0030018
GeneOntologyCellularComponent	junctional sarcoplasmic reticulum membrane	CASQ2 RYR1	1.10e-03	10	105	2	GO:0014701
MousePheno	abnormal spinal reflex	ABCA1 RYR1 DST PTPRG ARHGEF4 ALDH2 BBOX1	3.73e-05	148	87	7	MP:0012079
MousePheno	abnormal response to tactile stimuli	ABCA1 RYR1 DST PTPRG ARHGEF4 ALDH2 BBOX1	3.73e-05	148	87	7	MP:0005316
Domain	Munc13_1	UNC13D UNC13C CADPS2 BAIAP3	3.13e-08	7	104	4	IPR014770
Domain	MHD1	UNC13D UNC13C CADPS2 BAIAP3	3.13e-08	7	104	4	PS51258
Domain	DUF1041	UNC13D UNC13C CADPS2 BAIAP3	3.13e-08	7	104	4	PF06292
Domain	CAPS_dom	UNC13D UNC13C CADPS2 BAIAP3	3.13e-08	7	104	4	IPR010439
Domain	Ion_trans_N	HCN4 HCN1 HCN3	6.68e-07	4	104	3	IPR013621
Domain	Ion_trans_N	HCN4 HCN1 HCN3	6.68e-07	4	104	3	PF08412
Domain	Munc13_dom-2	UNC13D UNC13C BAIAP3	1.66e-06	5	104	3	IPR014772
Domain	MHD2	UNC13D UNC13C BAIAP3	1.66e-06	5	104	3	PS51259
Domain	Munc13_subgr_dom-2	UNC13D UNC13C BAIAP3	1.66e-06	5	104	3	IPR019558
Domain	Membr_traf_MHD	UNC13D UNC13C BAIAP3	1.66e-06	5	104	3	PF10540
Domain	DUOX1	DUOX2 DUOX1	3.07e-05	2	104	2	IPR029595
Domain	PDEase_PDE8	PDE8A PDE8B	3.07e-05	2	104	2	IPR013938
Domain	K_chnl_volt-dep_EAG/ELK/ERG	HCN4 HCN1 HCN3	5.84e-05	14	104	3	IPR003938
Domain	RQC_domain	RECQL BLM	9.18e-05	3	104	2	IPR018982
Domain	RQC	RECQL BLM	9.18e-05	3	104	2	PF09382
Domain	FAM86	FAM86B1 FAM86B2	1.83e-04	4	104	2	IPR029426
Domain	RecQ_Zn_bind	RECQL BLM	1.83e-04	4	104	2	PF16124
Domain	FAM86	FAM86B1 FAM86B2	1.83e-04	4	104	2	PF14904
Domain	RecQ_Zn-bd	RECQL BLM	1.83e-04	4	104	2	IPR032284
Domain	Spectrin	SPTAN1 SPTBN1 DST	2.74e-04	23	104	3	PF00435
Domain	DNA_helicase_ATP-dep_RecQ	RECQL BLM	3.04e-04	5	104	2	IPR004589
Domain	DUF1041	UNC13C CADPS2	3.04e-04	5	104	2	SM01145
Domain	Spectrin_repeat	SPTAN1 SPTBN1 DST	5.52e-04	29	104	3	IPR002017
Domain	NAD_binding_6	DUOX2 DUOX1	6.33e-04	7	104	2	PF08030
Domain	FAD_binding_8	DUOX2 DUOX1	6.33e-04	7	104	2	PF08022
Domain	FAD-bd_8	DUOX2 DUOX1	6.33e-04	7	104	2	IPR013112
Domain	Fe_red_NAD-bd_6	DUOX2 DUOX1	6.33e-04	7	104	2	IPR013121
Domain	SPEC	SPTAN1 SPTBN1 DST	7.40e-04	32	104	3	SM00150
Domain	CNMP_BINDING_1	HCN4 HCN1 HCN3	7.40e-04	32	104	3	PS00888
Domain	CNMP_BINDING_2	HCN4 HCN1 HCN3	7.40e-04	32	104	3	PS00889
Domain	Spectrin/alpha-actinin	SPTAN1 SPTBN1 DST	7.40e-04	32	104	3	IPR018159
Domain	cNMP	HCN4 HCN1 HCN3	8.85e-04	34	104	3	SM00100
Domain	cNMP_binding	HCN4 HCN1 HCN3	8.85e-04	34	104	3	PF00027
Domain	cNMP-bd_dom	HCN4 HCN1 HCN3	9.64e-04	35	104	3	IPR000595
Domain	CNMP_BINDING_3	HCN4 HCN1 HCN3	9.64e-04	35	104	3	PS50042
Domain	cNMP-bd-like	HCN4 HCN1 HCN3	1.23e-03	38	104	3	IPR018490
Domain	IPPc	INPP5K INPP5J	1.34e-03	10	104	2	IPR000300
Domain	An_peroxidase	DUOX2 DUOX1	1.34e-03	10	104	2	PF03098
Domain	Haem_peroxidase_animal	DUOX2 DUOX1	1.34e-03	10	104	2	IPR019791
Domain	IPPc	INPP5K INPP5J	1.34e-03	10	104	2	SM00128
Domain	Haem_peroxidase	DUOX2 DUOX1	1.34e-03	10	104	2	IPR010255
Domain	PEROXIDASE_3	DUOX2 DUOX1	1.34e-03	10	104	2	PS50292
Domain	-	DUOX2 DUOX1	1.34e-03	10	104	2	1.10.640.10
Domain	EF-hand_1	CAPN12 SPTAN1 DUOX2 DUOX1 DST	1.61e-03	152	104	5	PF00036
Domain	Methyltransf_16	FAM86B1 FAM86B2	1.63e-03	11	104	2	IPR019410
Domain	Methyltransf_16	FAM86B1 FAM86B2	1.63e-03	11	104	2	PF10294
Domain	EF_hand_dom	CAPN12 SPTAN1 DUOX2 RYR1 DUOX1 DST	1.90e-03	232	104	6	IPR002048
Domain	Ferric_reduct	DUOX2 DUOX1	1.95e-03	12	104	2	PF01794
Domain	Fe3_Rdtase_TM_dom	DUOX2 DUOX1	1.95e-03	12	104	2	IPR013130
Domain	-	HCN4 HCN1 HCN3	2.42e-03	48	104	3	2.60.120.10
Domain	RmlC-like_jellyroll	HCN4 HCN1 HCN3	2.88e-03	51	104	3	IPR014710
Domain	EF_Hand_1_Ca_BS	CAPN12 SPTAN1 DUOX2 DUOX1 DST	2.97e-03	175	104	5	IPR018247
Domain	-	CAPN12 SPTAN1 DUOX2 RYR1 DUOX1 DST	3.41e-03	261	104	6	1.10.238.10
Domain	cNMP-bd_CS	HCN4 HCN1	3.50e-03	16	104	2	IPR018488
Domain	Galactosyl_T	B3GNT5 B3GALT6	3.50e-03	16	104	2	PF01762
Domain	Glyco_trans_31	B3GNT5 B3GALT6	3.50e-03	16	104	2	IPR002659
Domain	Kelch-typ_b-propeller	KBTBD6 KBTBD7 CCIN	3.57e-03	55	104	3	IPR015915
Domain	Ion_trans_dom	HCN4 HCN1 HCN3 RYR1	3.79e-03	114	104	4	IPR005821
Domain	Ion_trans	HCN4 HCN1 HCN3 RYR1	3.79e-03	114	104	4	PF00520
Domain	AMP-bd_C	ACSM2A ACSM2B	3.95e-03	17	104	2	IPR025110
Domain	AMP-binding_C	ACSM2A ACSM2B	3.95e-03	17	104	2	PF13193
Domain	Kelch	KBTBD6 KBTBD7 CCIN	4.14e-03	58	104	3	SM00612
Domain	Gal_Oxase/kelch_b-propeller	KBTBD6 KBTBD7 CCIN	4.35e-03	59	104	3	IPR011043
Domain	aa-tRNA-synth_II	EPRS1 FARS2	4.43e-03	18	104	2	IPR006195
Domain	AA_TRNA_LIGASE_II	EPRS1 FARS2	4.43e-03	18	104	2	PS50862
Domain	-	FAM86B1 FAM86B2 COMT PRMT9	4.55e-03	120	104	4	3.40.50.150
Domain	BACK	KBTBD6 KBTBD7 CCIN	4.56e-03	60	104	3	SM00875
Domain	BACK	KBTBD6 KBTBD7 CCIN	4.78e-03	61	104	3	IPR011705
Domain	BACK	KBTBD6 KBTBD7 CCIN	4.78e-03	61	104	3	PF07707
Domain	SAM-dependent_MTases	FAM86B1 FAM86B2 COMT PRMT9	4.82e-03	122	104	4	IPR029063
Domain	PDEase	PDE8A PDE8B	4.94e-03	19	104	2	IPR023088
Domain	Fd_Rdtase_FAD-bd	DUOX2 DUOX1	4.94e-03	19	104	2	IPR017927
Domain	FAD_FR	DUOX2 DUOX1	4.94e-03	19	104	2	PS51384
Domain	Riboflavin_synthase-like_b-brl	DUOX2 DUOX1	4.94e-03	19	104	2	IPR017938
Domain	EF-hand-dom_pair	CAPN12 SPTAN1 DUOX2 RYR1 DUOX1 DST	5.40e-03	287	104	6	IPR011992
Domain	RCC1	ALS2 HERC3	5.47e-03	20	104	2	PF00415
Pubmed	Unconventional molecular regulation of synaptic vesicle replenishment in cochlear inner hair cells.	UNC13D UNC13C CADPS2 BAIAP3	5.44e-09	8	105	4	25609709
Pubmed	Functional expression of the human HCN3 channel.	HCN4 HCN1 HCN3	1.07e-07	4	105	3	16043489
Pubmed	Interactive cloning with the SH3 domain of N-src identifies a new brain specific ion channel protein, with homology to eag and cyclic nucleotide-gated channels.	HCN4 HCN1 HCN3	1.07e-07	4	105	3	9405696
Pubmed	Role of subunit heteromerization and N-linked glycosylation in the formation of functional hyperpolarization-activated cyclic nucleotide-gated channels.	HCN4 HCN1 HCN3	1.07e-07	4	105	3	12928435
Pubmed	Genetic analysis of hyperpolarization-activated cyclic nucleotide-gated cation channels in sudden unexpected death in epilepsy cases.	HCN4 HCN1 HCN3	1.07e-07	4	105	3	21615589
Pubmed	Hyperpolarization-activated and cyclic nucleotide-gated channels are differentially expressed in juxtaglomerular cells in the olfactory bulb of mice.	HCN4 HCN1 HCN3	1.07e-07	4	105	3	20140458
Pubmed	Investigation of hyperpolarization-activated cyclic nucleotide-gated channels in interstitial cells of Cajal of human bladder.	HCN4 HCN1 HCN3	1.07e-07	4	105	3	22748890
Pubmed	Identification of a gene encoding a hyperpolarization-activated pacemaker channel of brain.	HCN4 HCN1 HCN3	1.07e-07	4	105	3	9630217
Pubmed	Regulation of HCN channel surface expression by a novel C-terminal protein-protein interaction.	HCN4 HCN1 HCN3	2.66e-07	5	105	3	15564593
Pubmed	Developmental HCN channelopathy results in decreased neural progenitor proliferation and microcephaly in mice.	HCN4 HCN1 HCN3	2.66e-07	5	105	3	34429357
Pubmed	Identification of a Munc13-sensitive step in chromaffin cell large dense-core vesicle exocytosis.	UNC13D UNC13C BAIAP3	2.66e-07	5	105	3	26575293
Pubmed	Transcription profiling of HCN-channel isotypes throughout mouse cardiac development.	HCN4 HCN1 HCN3	9.28e-07	7	105	3	19421833
Pubmed	Chr21 protein-protein interactions: enrichment in proteins involved in intellectual disability, autism, and late-onset Alzheimer's disease.	EPRS1 FAM86B1 USP13 MAGED1 HCN1 SPTAN1 SPTBN1 HECTD4 USP25 OBSL1 LDB2 DST PTPRD MAP3K10 CADPS2 SULT4A1	1.56e-06	1285	105	16	35914814
Pubmed	Proteomic analyses reveal distinct chromatin-associated and soluble transcription factor complexes.	UBR2 POLE OBSL1 RECQL ACTL6A ADNP JMJD1C KBTBD7 LDB2 BLM MDN1 L3MBTL3 HSD17B8	1.95e-06	857	105	13	25609649
Pubmed	International Union of Pharmacology. LI. Nomenclature and structure-function relationships of cyclic nucleotide-regulated channels.	HCN4 HCN1 HCN3	3.16e-06	10	105	3	16382102
Pubmed	Spatiotemporal profile of postsynaptic interactomes integrates components of complex brain disorders.	MAGED1 HCN4 HCN1 SPTAN1 SPTBN1 HCN3 HECTD4 ADNP LDB2 MAP3K5 DST MDN1 PTPRD	6.91e-06	963	105	13	28671696
Pubmed	Digenic DUOX1 and DUOX2 Mutations in Cases With Congenital Hypothyroidism.	DUOX2 DUOX1	9.03e-06	2	105	2	28633507
Pubmed	cAMP-specific phosphodiesterases 8A and 8B, essential regulators of Leydig cell steroidogenesis.	PDE8A PDE8B	9.03e-06	2	105	2	22232524
Pubmed	The L513S polymorphism in medium-chain acyl-CoA synthetase 2 (MACS2) is associated with risk factors of the metabolic syndrome in a Caucasian study population.	ACSM2A ACSM2B	9.03e-06	2	105	2	16521160
Pubmed	Congenital Hypothyroidism due to Oligogenic Mutations in Two Sudanese Families.	DUOX2 DUOX1	9.03e-06	2	105	2	30375286
Pubmed	Cloning of two human thyroid cDNAs encoding new members of the NADPH oxidase family.	DUOX2 DUOX1	9.03e-06	2	105	2	10806195
Pubmed	Tyrosine cross-linking of extracellular matrix is catalyzed by Duox, a multidomain oxidase/peroxidase with homology to the phagocyte oxidase subunit gp91phox.	DUOX2 DUOX1	9.03e-06	2	105	2	11514595
Pubmed	Roles of DUOX-mediated hydrogen peroxide in metabolism, host defense, and signaling.	DUOX2 DUOX1	9.03e-06	2	105	2	24161126
Pubmed	Reactive oxygen species regulate the levels of dual oxidase (Duox1-2) in human neuroblastoma cells.	DUOX2 DUOX1	9.03e-06	2	105	2	22523549
Pubmed	Expression of dual oxidases and secreted cytokines in chronic rhinosinusitis.	DUOX2 DUOX1	9.03e-06	2	105	2	23281318
Pubmed	The high-affinity cAMP-specific phosphodiesterase 8B controls steroidogenesis in the mouse adrenal gland.	PDE8A PDE8B	9.03e-06	2	105	2	21187369
Pubmed	Peripheral N- and C-terminal domains determine deactivation kinetics of HCN channels.	HCN4 HCN1	9.03e-06	2	105	2	17548059
Pubmed	Colocalization of hyperpolarization-activated, cyclic nucleotide-gated channel subunits in rat retinal ganglion cells.	HCN4 HCN1	9.03e-06	2	105	2	21456027
Pubmed	Dual oxidase 1 and NADPH oxidase 2 exert favorable effects in cervical cancer patients by activating immune response.	DUOX2 DUOX1	9.03e-06	2	105	2	31706280
Pubmed	Hyperpolarization-activated channels HCN1 and HCN4 mediate responses to sour stimuli.	HCN4 HCN1	9.03e-06	2	105	2	11675786
Pubmed	Expression of reduced nicotinamide adenine dinucleotide phosphate oxidase (ThoX, LNOX, Duox) genes and proteins in human thyroid tissues.	DUOX2 DUOX1	9.03e-06	2	105	2	11443211
Pubmed	Purification of a novel flavoprotein involved in the thyroid NADPH oxidase. Cloning of the porcine and human cdnas.	DUOX2 DUOX1	9.03e-06	2	105	2	10601291
Pubmed	Identification of a mouse brain beta-spectrin cDNA and distribution of its mRNA in adult tissues.	SPTAN1 SPTBN1	9.03e-06	2	105	2	1742606
Pubmed	COMT and ALDH2 polymorphisms moderate associations of implicit drinking motives with alcohol use.	COMT ALDH2	9.03e-06	2	105	2	21309949
Pubmed	Comparative analyses of disease risk genes belonging to the acyl-CoA synthetase medium-chain (ACSM) family in human liver and cell lines.	ACSM2A ACSM2B	9.03e-06	2	105	2	19634011
Pubmed	Dual oxidase-2 has an intrinsic Ca2+-dependent H2O2-generating activity.	DUOX2 DUOX1	9.03e-06	2	105	2	15972824
Pubmed	The extracellular A-loop of dual oxidases affects the specificity of reactive oxygen species release.	DUOX2 DUOX1	9.03e-06	2	105	2	25586178
Pubmed	Conserved cysteine residues provide a protein-protein interaction surface in dual oxidase (DUOX) proteins.	DUOX2 DUOX1	9.03e-06	2	105	2	23362256
Pubmed	Activation of dual oxidases Duox1 and Duox2: differential regulation mediated by camp-dependent protein kinase and protein kinase C-dependent phosphorylation.	DUOX2 DUOX1	9.03e-06	2	105	2	19144650
Pubmed	HCN3 contributes to the ventricular action potential waveform in the murine heart.	HCN1 HCN3	9.03e-06	2	105	2	21903939
Pubmed	Analyses of the genetic diversity and protein expression variation of the acyl: CoA medium-chain ligases, ACSM2A and ACSM2B.	ACSM2A ACSM2B	9.03e-06	2	105	2	29948332
Pubmed	Differential regulation of dual NADPH oxidases/peroxidases, Duox1 and Duox2, by Th1 and Th2 cytokines in respiratory tract epithelium.	DUOX2 DUOX1	9.03e-06	2	105	2	16111680
Pubmed	Molecular composition and functional properties of f-channels in murine embryonic stem cell-derived pacemaker cells.	HCN4 HCN1	9.03e-06	2	105	2	19135060
Pubmed	The Human RecQ helicases, BLM and RECQ1, display distinct DNA substrate specificities.	RECQL BLM	9.03e-06	2	105	2	18448429
Pubmed	Expression of nicotinamide adenine dinucleotide phosphate oxidase flavoprotein DUOX genes and proteins in human papillary and follicular thyroid carcinomas.	DUOX2 DUOX1	9.03e-06	2	105	2	11762710
Pubmed	Characterization of ThOX proteins as components of the thyroid H(2)O(2)-generating system.	DUOX2 DUOX1	9.03e-06	2	105	2	11822874
Pubmed	Nox/Duox family of nicotinamide adenine dinucleotide (phosphate) oxidases.	DUOX2 DUOX1	9.03e-06	2	105	2	11753072
Pubmed	Silencing of DUOX NADPH oxidases by promoter hypermethylation in lung cancer.	DUOX2 DUOX1	9.03e-06	2	105	2	18281478
Pubmed	Structural and functional characterization of the two human ThOX/Duox genes and their 5'-flanking regions.	DUOX2 DUOX1	9.03e-06	2	105	2	15062544
Pubmed	Regulated hydrogen peroxide production by Duox in human airway epithelial cells.	DUOX2 DUOX1	9.03e-06	2	105	2	15677770
Pubmed	Spectrin-actin interaction is required for neurite extension in NB 2a/dl neuroblastoma cells.	SPTAN1 SPTBN1	9.03e-06	2	105	2	8776664
Pubmed	Dual oxidase 1 and 2 expression in airway epithelium of smokers and patients with mild/moderate chronic obstructive pulmonary disease.	DUOX2 DUOX1	9.03e-06	2	105	2	18177232
Pubmed	Comparison of enzymatic characterization and gene organization of cyclic nucleotide phosphodiesterase 8 family in humans.	PDE8A PDE8B	9.03e-06	2	105	2	12681444
Pubmed	Cloning of a portion of the chromosomal gene and cDNA for human beta-fodrin, the nonerythroid form of beta-spectrin.	SPTAN1 SPTBN1	9.03e-06	2	105	2	8406479
Pubmed	Mucosal reactive oxygen species are required for antiviral response: role of Duox in influenza a virus infection.	DUOX2 DUOX1	9.03e-06	2	105	2	24128054
Pubmed	cAMP-specific phosphodiesterase 8A and 8B isoforms are differentially expressed in human testis and Leydig cell tumor.	PDE8A PDE8B	9.03e-06	2	105	2	36277728
Pubmed	Dual oxidases represent novel hydrogen peroxide sources supporting mucosal surface host defense.	DUOX2 DUOX1	9.03e-06	2	105	2	12824283
Pubmed	Pacsin 2 is required for the maintenance of a normal cardiac function in the developing mouse heart.	HCN4 HCN1 HCN3	9.50e-06	14	105	3	29107716
Pubmed	HCN channels in the mammalian cochlea: Expression pattern, subcellular location, and age-dependent changes.	HCN4 HCN1	2.70e-05	3	105	2	33181864
Pubmed	Ventricular HCN channels decrease the repolarization reserve in the hypertrophic heart.	HCN4 HCN1	2.70e-05	3	105	2	22652004
Pubmed	Accelerated activation of SOCE current in myotubes from two mouse models of anesthetic- and heat-induced sudden death.	CASQ2 RYR1	2.70e-05	3	105	2	24143248
Pubmed	Exome-wide association study identifies genetic polymorphisms of C12orf51, MYL2, and ALDH2 associated with blood lead levels in the general Korean population.	HECTD4 ALDH2	2.70e-05	3	105	2	28212632
Pubmed	NADPH oxidase-dependent acid production in airway epithelial cells.	DUOX2 DUOX1	2.70e-05	3	105	2	15210697
Pubmed	Cytoplasmic cAMP-sensing domain of hyperpolarization-activated cation (HCN) channels uses two structurally distinct mechanisms to regulate voltage gating.	HCN4 HCN1	2.70e-05	3	105	2	21187420
Pubmed	Conditional ablation and conditional rescue models for Casq2 elucidate the role of development and of cell-type specific expression of Casq2 in the CPVT2 phenotype.	HCN4 CASQ2	2.70e-05	3	105	2	29452352
Pubmed	Interaction of DRD2TaqI, COMT, and ALDH2 genes associated with bipolar II disorder comorbid with anxiety disorders in Han Chinese in Taiwan.	COMT ALDH2	2.70e-05	3	105	2	25430946
Pubmed	Polarity and bypass of DNA heterology during branch migration of Holliday junctions by human RAD54, BLM, and RECQ1 proteins.	RECQL BLM	2.70e-05	3	105	2	22356911
Pubmed	Novel insights into the distribution of cardiac HCN channels: an expression study in the mouse heart.	HCN4 HCN1	2.70e-05	3	105	2	21945247
Pubmed	Negatively charged amino acids within the intraluminal loop of ryanodine receptor are involved in the interaction with triadin.	CASQ2 RYR1	2.70e-05	3	105	2	14638677
Pubmed	Role of nicotinamide adenine dinucleotide phosphate oxidase in mediating vesicant-induced interleukin-6 secretion in human airway epithelial cells.	DUOX2 DUOX1	2.70e-05	3	105	2	24164541
Pubmed	Tetramerization dynamics of C-terminal domain underlies isoform-specific cAMP gating in hyperpolarization-activated cyclic nucleotide-gated channels.	HCN4 HCN1	2.70e-05	3	105	2	22006928
Pubmed	DUOX enzyme activity promotes AKT signalling in prostate cancer cells.	DUOX2 DUOX1	2.70e-05	3	105	2	23225414
Pubmed	EP3 activation facilitates bladder excitability via HCN channels on ICCs.	HCN4 HCN1	2.70e-05	3	105	2	28131828
Pubmed	NADPH oxidase DUOX1 and DUOX2 but not NOX4 are independent predictors in hepatocellular carcinoma after hepatectomy.	DUOX2 DUOX1	2.70e-05	3	105	2	21915726
Pubmed	Association of triadin with the ryanodine receptor and calsequestrin in the lumen of the sarcoplasmic reticulum.	CASQ2 RYR1	2.70e-05	3	105	2	7721813
Pubmed	The complete amino acid sequence for brain beta spectrin (beta fodrin): relationship to globin sequences.	SPTAN1 SPTBN1	2.70e-05	3	105	2	8479293
Pubmed	Aldehyde dehydrogenase 2 and PARP1 interaction modulates hepatic HDL biogenesis by LXRα-mediated ABCA1 expression.	ABCA1 ALDH2	2.70e-05	3	105	2	35393951
Pubmed	Interaction of the C-terminal domain of delta glutamate receptor with spectrin in the dendritic spines of cultured Purkinje cells.	SPTAN1 SPTBN1	2.70e-05	3	105	2	10576550
Pubmed	The KBTBD6/7-DRD2 axis regulates pituitary adenoma sensitivity to dopamine agonist treatment.	KBTBD6 KBTBD7	2.70e-05	3	105	2	32572597
Pubmed	Developmental expression of brain beta-spectrin isoform messenger RNAs.	SPTAN1 SPTBN1	2.70e-05	3	105	2	1467942
Pubmed	Association of duoxes with thyroid peroxidase and its regulation in thyrocytes.	DUOX2 DUOX1	2.70e-05	3	105	2	19952225
Pubmed	alpha -Catenin binds directly to spectrin and facilitates spectrin-membrane assembly in vivo.	SPTAN1 SPTBN1	2.70e-05	3	105	2	11069925
Pubmed	A family of hyperpolarization-activated mammalian cation channels.	HCN1 HCN3	2.70e-05	3	105	2	9634236
Pubmed	Prediction of the coding sequences of mouse homologues of KIAA gene: II. The complete nucleotide sequences of 400 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.	UBR2 RAPGEF5 OBSL1 ALS2 HERC3 ARHGEF4 NFAT5 BAIAP3	3.41e-05	407	105	8	12693553
Pubmed	Increased expression of hyperpolarization-activated cyclic nucleotide-gated (HCN) channels in reactive astrocytes following ischemia.	HCN1 HCN3	5.40e-05	4	105	2	25042871
Pubmed	Clinical and genetic characteristics of Korean male alcoholics with and without attention deficit hyperactivity disorder.	COMT ALDH2	5.40e-05	4	105	2	16679343
Pubmed	Autism-associated SHANK3 haploinsufficiency causes Ih channelopathy in human neurons.	HCN1 HCN3	5.40e-05	4	105	2	26966193
Pubmed	Nox4 and Duox1/2 Mediate Redox Activation of Mesenchymal Cell Migration by PDGF.	DUOX2 DUOX1	5.40e-05	4	105	2	27110716
Pubmed	Common variants at 12q24 are associated with drinking behavior in Han Chinese.	HECTD4 ALDH2	5.40e-05	4	105	2	23364009
Pubmed	The spectrin-based membrane skeleton stabilizes mouse megakaryocyte membrane systems and is essential for proplatelet and platelet formation.	SPTAN1 SPTBN1	5.40e-05	4	105	2	21566095
Pubmed	Remarkable homology among the internal repeats of erythroid and nonerythroid spectrin.	SPTAN1 SPTBN1	5.40e-05	4	105	2	3862089
Pubmed	Phosphorylation of a threonine unique to the short C-terminal isoform of betaII-spectrin links regulation of alpha-beta spectrin interaction to neuritogenesis.	SPTAN1 SPTBN1	5.40e-05	4	105	2	17088250
Pubmed	The type of DUOX-dependent ROS production is dictated by defined sequences in DUOXA.	DUOX2 DUOX1	5.40e-05	4	105	2	22814254
Pubmed	Expression of Acsm2, a kidney-specific gene, parallels the function and maturation of proximal tubular cells.	ACSM2A ACSM2B	5.40e-05	4	105	2	32830538
Pubmed	Brain beta spectrin isoform 235 (Spnb-2) maps to mouse chromosome 11.	SPTAN1 SPTBN1	5.40e-05	4	105	2	1638088
Pubmed	Heterodimerization controls localization of Duox-DuoxA NADPH oxidases in airway cells.	DUOX2 DUOX1	5.40e-05	4	105	2	19339556
Pubmed	Spectrin alpha II and beta II isoforms interact with high affinity at the tetramerization site.	SPTAN1 SPTBN1	5.40e-05	4	105	2	12820899
Pubmed	Impaired nigrostriatal function precedes behavioral deficits in a genetic mitochondrial model of Parkinson's disease.	HCN1 HCN3	5.40e-05	4	105	2	21233488
Pubmed	NDP52 interacts with mitochondrial RNA poly(A) polymerase to promote mitophagy.	SPTAN1 SPTBN1 MYO5C	5.86e-05	25	105	3	30309841
Pubmed	siRNA screening identifies differences in the Fanconi anemia pathway in BALB/c-Trp53+/- with susceptibility versus C57BL/6-Trp53+/- mice with resistance to mammary tumors.	POLE RECQL BLM	6.61e-05	26	105	3	23435420
Interaction	PEX5L interactions	HCN4 HCN1 SPTAN1 SPTBN1 HCN3	7.82e-06	54	102	5	int:PEX5L
Interaction	HCN4 interactions	HCN4 HCN1 HCN3	1.03e-05	9	102	3	int:HCN4
Interaction	DUSP26 interactions	UBR2 POLE PFAS PTPRG PRMT9	1.21e-05	59	102	5	int:DUSP26
Interaction	HCN3 interactions	HCN4 HCN1 HCN3	2.02e-05	11	102	3	int:HCN3
Interaction	GRIK1 interactions	HCN1 OBSL1 LDB2 PTPRD	3.22e-05	36	102	4	int:GRIK1
Cytoband	9q31.1	ABCA1 OR13C5 OR13C2	1.16e-04	41	105	3	9q31.1
Cytoband	Ensembl 112 genes in cytogenetic band chr15q21	DUOX2 MYO5C DUOX1 UNC13C	7.54e-04	177	105	4	chr15q21
Cytoband	3q26.33	ACTL6A CCDC39	1.27e-03	23	105	2	3q26.33
Cytoband	7q32	CPA5 WEE2	1.38e-03	24	105	2	7q32
Cytoband	15q15.3	DUOX2 DUOX1	1.50e-03	25	105	2	15q15.3
Cytoband	1p13.1	CASQ2 PTGFRN	2.61e-03	33	105	2	1p13.1
Cytoband	15q24.1	HCN4 TBC1D21	2.77e-03	34	105	2	15q24.1
Cytoband	16p12.3	ACSM2A ACSM2B	2.77e-03	34	105	2	16p12.3
GeneFamily	Cyclic nucleotide gated channels	HCN4 HCN1 HCN3	1.18e-05	10	85	3	250
GeneFamily	UNC13 homologs	UNC13D UNC13C	1.30e-04	4	85	2	836
GeneFamily	RecQ like helicases	RECQL BLM	2.16e-04	5	85	2	1049
GeneFamily	EF-hand domain containing\|Spectrins	SPTAN1 SPTBN1	4.52e-04	7	85	2	1113
GeneFamily	Aminoacyl tRNA synthetases, Class II	EPRS1 FARS2	3.55e-03	19	85	2	132
GeneFamily	EF-hand domain containing	CAPN12 SPTAN1 DUOX2 DUOX1 DST	3.73e-03	219	85	5	863
GeneFamily	Protein tyrosine phosphatases, receptor type	PTPRD PTPRG	4.33e-03	21	85	2	813
GeneFamily	Olfactory receptors, family 13	OR13C5 OR13C2	5.18e-03	23	85	2	162
GeneFamily	Mitogen-activated protein kinase kinase kinases\|RAF family	MAP3K5 MAP3K10	5.64e-03	24	85	2	654
GeneFamily	Beta 3-glycosyltransferases	B3GNT5 B3GALT6	5.64e-03	24	85	2	426
GeneFamily	Phosphodiesterases	PDE8A PDE8B	5.64e-03	24	85	2	681
GeneFamily	Acyl-CoA synthetase family	ACSM2A ACSM2B	6.60e-03	26	85	2	40
CoexpressionAtlas	DevelopingKidney_e15.5_cortic collect duct_emap-28132_k-means-cluster#3_top-relative-expression-ranked_1000	B3GALT6 CHRNB1 MYO5C PDE8B CADPS2 FAM149A	3.16e-05	124	103	6	gudmap_developingKidney_e15.5_cortic collect duct_1000_k3
CoexpressionAtlas	DevelopingKidney_e15.5_Pelvic Mesenchyme_emap-8241_top-relative-expression-ranked_500	ABCA1 SPTBN1 B3GALT6 LDB2 MRC2 HAS2 CADPS2 SCIN ACSM2A NFAT5	3.21e-05	412	103	10	gudmap_developingKidney_e15.5_Pelvic Mesenchyme_500
CoexpressionAtlas	DevelopingKidney_e15.5_Pelvic Mesenchyme_emap-8241_top-relative-expression-ranked_1000	ABCA1 PRICKLE1 SPTBN1 B3GALT6 LDB2 MAP3K5 PCYOX1L MRC2 HAS2 CADPS2 SCIN ACSM2A NFAT5 IPO11	3.60e-05	809	103	14	gudmap_developingKidney_e15.5_Pelvic Mesenchyme_1000
CoexpressionAtlas	DevelopingLowerUrinaryTract_e15.5_Urothelium_emap-28091_k-means-cluster#4_top-relative-expression-ranked_200	B3GALT6 SCIN NFAT5 FAM149A	4.61e-05	41	103	4	gudmap_developingLowerUrinaryTract_e15.5_Urothelium_200_k4
CoexpressionAtlas	Pluripotent Stem Cells-reprogram_NA_vs_Pluripotent Stem Cells-reprogram_OSK-L-l-p53KD-Confounder_removed-fold2.0_adjp0.05	FAM86B1 FAM86B2	6.97e-05	3	103	2	PCBC_ratio_ESC_vs_iPSC_method-OSK-L-l-p53KD_cfr-2X-p05
CoexpressionAtlas	DevelopingLowerUrinaryTract_e15.5_Urothelium_emap-28091_top-relative-expression-ranked_200	B3GALT6 DST CADPS2 SCIN NFAT5 FAM149A	1.18e-04	157	103	6	gudmap_developingLowerUrinaryTract_e15.5_urothelium_200
ToppCell	COVID-19-kidney-tDL\|COVID-19 / Disease (COVID-19 only), tissue and cell type	CAPN12 MSRA PTPRD AKR1B10 ACSM2A BBOX1 ACSM2B	2.39e-07	180	105	7	864c895b5eaedefae86f5829fa344f7b686fb59f
ToppCell	Monocytes-Tissue-resident_macrophages\|World / Immune cells in Kidney/Urine in Lupus Nephritis	B3GNT5 OLFML2B DST MRC2 ALDH2 ADAP2 FAM149A	3.44e-07	190	105	7	07215e8f292cb54c670037aaf28393cddbe5548c
ToppCell	Control_saline-Endothelial-Endothelial-Gen_Cap\|Control_saline / Treatment groups by lineage, cell group, cell type	RAPGEF5 SPTAN1 SPTBN1 JMJD1C LDB2 DST PTPRG	4.86e-07	200	105	7	3b97920e1e6e2f09ddba2a861baa9c00c2970f4c
ToppCell	10x5'-Liver-Myeloid_Mac-Intestinal_macrophages\|Liver / Manually curated celltypes from each tissue	ABCA1 UBD PTGFRN DST MRC2 ADAP2	1.91e-06	156	105	6	9a897fc79c4fae94c5f2e9012d65297f9225e5e3
ToppCell	Adult-Epithelial-alveolar_epithelial_cell_type_1/2_(AT1/AT2-like)-D122\|Adult / Lineage, Cell type, age group and donor	CAPN12 OBSL1 DUOX1 PTPRG ATP6V1C2 FAM149A	1.99e-06	157	105	6	31d1bd9138c60e8485664ec4144f987226e3eef9
ToppCell	TCGA-Brain-Primary_Tumor-Low_Grade_Glioma-Oligoastrocytoma\|TCGA-Brain / Sample_Type by Project: Shred V9	RYR1 MAP3K5 DST MDN1 PTPRD ALDH2	2.30e-06	161	105	6	347edb0de10850b7d16c40945751033289289c9b
ToppCell	Cerebellum-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)\|Cerebellum / BrainAtlas - Mouse McCarroll V32	MAGED1 B3GNT5 HCN1 ADNP SEMA4G INPP5J	2.84e-06	167	105	6	9efb9511a211d0824bb97f82c1a5860c43d2138f
ToppCell	Cerebellum-Neuronal-Inhibitory\|Cerebellum / BrainAtlas - Mouse McCarroll V32	MAGED1 B3GNT5 HCN1 ADNP SEMA4G INPP5J	2.84e-06	167	105	6	904c613aac3f9919a432b110bb1dcc832b5aec0a
ToppCell	TCGA-Thryoid-Primary_Tumor-Thyroid_Papillary_Carcinoma-Classical-8\|TCGA-Thryoid / Sample_Type by Project: Shred V9	ABCA1 RAPGEF5 SPTAN1 PTPRG L3MBTL3 BAIAP3	2.94e-06	168	105	6	00646601548b0fee42ae16bfa5e93603bc7c5129
ToppCell	renal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Proximal_Tubule_Epithelial_Cell_Segment_3\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	CAPN12 MSRA PTPRD ACSM2A BBOX1 ACSM2B	3.84e-06	176	105	6	1595dbeee336a81e581325d63208ec6262664ee9
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	CAPN12 MSRA PTPRD ACSM2A BBOX1 ACSM2B	4.66e-06	182	105	6	e1e58176f533092b6b974ca1ce8b02192a6e193d
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Proximal_Tubule_Epithelial_Cell_Segment_3\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	CAPN12 MSRA PTPRD ACSM2A BBOX1 ACSM2B	4.66e-06	182	105	6	4a9c13932e7163fd37a3dcc4c6ca3bbea5372459
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Epithelial-Proximal_tubule_epithelial_cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	CAPN12 MSRA PTPRD ACSM2A BBOX1 ACSM2B	4.66e-06	182	105	6	57bb5a2da976464ba7c4460106bd9f692008ebd9
ToppCell	COVID-19-kidney-FLT1+PLVAP+EC\|COVID-19 / Disease (COVID-19 only), tissue and cell type	USP13 PDE8A RAPGEF5 SPTBN1 JMJD1C LDB2	5.12e-06	185	105	6	673308ca0514a4d3629d61fe91e9d8fb31b72166
ToppCell	renal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	CAPN12 MSRA PTPRD ACSM2A BBOX1 ACSM2B	5.28e-06	186	105	6	8287146f0ba415ea04475588117d4668ae00f75c
ToppCell	primary_auditory_cortex_(A1C)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)\|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	RAPGEF5 LDB2 MSRA PTPRD UNC13C CADPS2	5.44e-06	187	105	6	f18628ffc7ff7c762b8339ba8822cf0c3157f469
ToppCell	10x3'2.3-week_12-13-Mesenchymal_adipo\|week_12-13 / cell types per 3 fetal stages;per 3',per 5'	OLFML2B TEKT5 UNC13C HAS2 SCIN BBOX1	5.44e-06	187	105	6	f1d0fc625e0e7881b3f290742fd7148d995eb71e
ToppCell	10x3'2.3-week_12-13-Mesenchymal_adipo-stroma\|week_12-13 / cell types per 3 fetal stages;per 3',per 5'	OLFML2B TEKT5 UNC13C HAS2 SCIN BBOX1	5.44e-06	187	105	6	02e7246ef5ad41773d14426254e139b156d45c1d
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	CAPN12 MSRA PTPRD ACSM2A BBOX1 ACSM2B	5.44e-06	187	105	6	1b82920588f9e26ef1db244d452736d75fcfd342
ToppCell	Cerebellum-Neuronal\|Cerebellum / BrainAtlas - Mouse McCarroll V32	USP13 HCN1 HCN3 ATP1A3 SULT4A1 INPP5J	5.44e-06	187	105	6	61b9d6eb131a674598aa8409d7fa909c8765442d
ToppCell	renal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Proximal_tubule_epithelial_cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	CAPN12 MSRA PTPRD ACSM2A BBOX1 ACSM2B	5.44e-06	187	105	6	71eb26ebf60cb0848e5bf1cd01edccda621aecd8
ToppCell	COVID-19-kidney-tDL\|kidney / Disease (COVID-19 only), tissue and cell type	CAPN12 MSRA PTPRD AKR1B10 ACSM2A ACSM2B	5.44e-06	187	105	6	d35d27ca3c0e65f92f4508e1cb98a743f44fdcdf
ToppCell	10x3'2.3-week_12-13-Mesenchymal_adipo-stroma-adipo-CAR\|week_12-13 / cell types per 3 fetal stages;per 3',per 5'	OLFML2B TEKT5 UNC13C HAS2 SCIN BBOX1	5.44e-06	187	105	6	08c73d125e0638c9e9878165bba2442c266c8a48
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Proximal_tubule_epithelial_cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	CAPN12 MSRA PTPRD ACSM2A BBOX1 ACSM2B	5.44e-06	187	105	6	c1e4c0345f9bfa0538730bad5ff3fa5240168b25
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Proximal_tubule_epithelial_cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	CAPN12 MSRA PTPRD ACSM2A BBOX1 ACSM2B	5.61e-06	188	105	6	f3edcefeef2ce19086032d98b243c02a6d542b38
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	CAPN12 MSRA PTPRD ACSM2A BBOX1 ACSM2B	5.61e-06	188	105	6	0792432cd4c564dea1102241ea9884f7ced7658c
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	CAPN12 MSRA PTPRD ACSM2A BBOX1 ACSM2B	5.78e-06	189	105	6	204ab61ae606b2d9be0cb6bf6a83a011740693a8
ToppCell	primary_auditory_cortex_(A1C)-Neuronal-Glutamatergic_Excit\|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	PRICKLE1 RAPGEF5 LDB2 MSRA PTPRD CADPS2	5.96e-06	190	105	6	49e09cdb843b3d889a06a811aa5affae68b25a75
ToppCell	Children_(3_yrs)-Epithelial-alveolar_epithelial_cell_type_2\|Children_(3_yrs) / Lineage, Cell type, age group and donor	RAPGEF5 MYO5C DUOX1 PTPRD PTPRG CADPS2	6.14e-06	191	105	6	a0332a4ef629510fb313ec119195c44a3f704a80
ToppCell	Children_(3_yrs)-Epithelial-alveolar_epithelial_cell_type_2-D139\|Children_(3_yrs) / Lineage, Cell type, age group and donor	RAPGEF5 MYO5C DUOX1 PTPRG CADPS2 FAM149A	6.33e-06	192	105	6	cc9911e182a289779a2612bc213daae5607689e7
ToppCell	renal_cortex_nuclei\|World / Celltypes from Cells and Nuclei per compartment and clinical group	PDE8A JMJD1C PTPRD PTPRG ACSM2A ACSM2B	6.33e-06	192	105	6	e8cc4d08fcfceeab75a02558817e4ccd7dbafe3a
ToppCell	PCW_13-14-Mesenchymal-Mesenchymal_fibroblastic-mes_immature5_(6)\|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung	SPTBN1 DST PTPRD PTPRG UNC13C HAS2	6.72e-06	194	105	6	b1bb0f846d2865efdd9bc8842b16b9d069785882
ToppCell	Children_(3_yrs)-Epithelial-alveolar_epithelial_cell_type_2-D032\|Children_(3_yrs) / Lineage, Cell type, age group and donor	USP13 RAPGEF5 DUOX1 PTPRD PTPRG CADPS2	6.72e-06	194	105	6	97534c8bba895a7913665e03ae4e5c4a6ad71daf
ToppCell	PCW_10-12-Mesenchymal-Mesenchymal_fibroblastic-mes_immature5_(6)\|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung	SPTBN1 DST PTPRD PTPRG UNC13C HAS2	6.92e-06	195	105	6	0e55fa5b3cbeb7baee3d4ac272a3bf80381ec937
ToppCell	10x5'v1-week_17-19-Mesenchymal_osteo-stroma-osteoblast_precursor\|week_17-19 / cell types per 3 fetal stages;per 3',per 5'	OLFML2B PTGFRN PTPRD MRC2 HAS2 SCIN	7.12e-06	196	105	6	57df2a57b35be9851ac0b1e5731baa53052511f0
ToppCell	renal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-Collagen-low_Matrisome-low_fibroblast\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	PRICKLE1 LDB2 MAP3K5 MRC2 ADGRE5 HAS2	7.33e-06	197	105	6	b349f8e96d61a4c296af64711e11fc44459a9413
ToppCell	renal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-Collagen-low_Matrisome-low_fibroblast-\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	PRICKLE1 LDB2 MAP3K5 MRC2 ADGRE5 HAS2	7.33e-06	197	105	6	c2e390653d5dee7e731c1840cfdab41987dede9b
ToppCell	Control_saline\|World / Treatment groups by lineage, cell group, cell type	SPTAN1 SPTBN1 UNC13D LDB2 DST PTPRG	7.77e-06	199	105	6	11c9c1779caceb725ecccf3f23b7d4e6dbd1af64
ToppCell	Neuron-Postmitotic-Excitatory_Neuron_-Parietal_and_Temporal-6\|World / Primary Cells by Cluster	RAPGEF5 SPTAN1 MSRA DST PTPRD UNC13C	7.77e-06	199	105	6	1b1bccf4293f11048709d15a3c892c0edf3da3d2
ToppCell	Neuron-Postmitotic-Excitatory_Neuron_-Parietal_and_Temporal\|World / Primary Cells by Cluster	RAPGEF5 SPTAN1 MSRA DST PTPRD UNC13C	7.77e-06	199	105	6	4bee94c116c0da5eba951cb4cea7cc9dcdd6e30f
ToppCell	LPS_IL1RA-Endothelial-Endothelial-Gen_Cap\|LPS_IL1RA / Treatment groups by lineage, cell group, cell type	RAPGEF5 SPTAN1 SPTBN1 LDB2 DST PTPRG	7.99e-06	200	105	6	dccec522ab0d7fff62ad6273b02aa9022dbbb8eb
ToppCell	Influenza-Influenza_Severe-Myeloid-cDC\|Influenza_Severe / Disease, condition lineage and cell class	FAM86B1 OBSL1 PTGFRN CCIN MYO5C HSD17B8	7.99e-06	200	105	6	b8415a68ad6f4fea562236a1b0da0dc376d874fb
ToppCell	Control_saline-Endothelial-Endothelial\|Control_saline / Treatment groups by lineage, cell group, cell type	RAPGEF5 SPTAN1 SPTBN1 LDB2 DST PTPRG	7.99e-06	200	105	6	e77eba6172cabf85b8028638ed35299f2f079cd8
ToppCell	LPS_anti-TNF-Endothelial-Endothelial-Gen_Cap\|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type	RAPGEF5 SPTAN1 SPTBN1 LDB2 DST PTPRG	7.99e-06	200	105	6	a2b9d1cd291d17abddc3ee2e242121412c864b8b
ToppCell	Control_saline-Endothelial\|Control_saline / Treatment groups by lineage, cell group, cell type	RAPGEF5 SPTAN1 SPTBN1 LDB2 DST PTPRG	7.99e-06	200	105	6	3372c488a39fe812fa94e4f0564594186fea3db5
ToppCell	severe_influenza-NK_CD56bright\|World / disease group, cell group and cell class (v2)	CAPN12 FAM86B1 LDB2 DUOX1 WEE2	3.23e-05	154	105	5	187b9d4eb0e98c506034735601ead480ff00bd57
ToppCell	PND03-Endothelial-Endothelial_blood-vessel-Microvascular_EC-CAP1-CAP1_prolif\|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	RAPGEF5 POLE LDB2 BLM SCIN	3.54e-05	157	105	5	2c946c6ab284fac3c25db688ed0aabe5a3f9ffa5
ToppCell	Smart-seq2-tissue-resident_(Smart-seq2)-myeloid-myeloid_macrophage-microglial_cell\|tissue-resident_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type	B3GNT5 DST ALDH2 SCIN FAM149A	3.54e-05	157	105	5	d4908cafd8870c1c225817f589ea2bce116ac7ab
ToppCell	PBMC_fresh-frozen-Severe-critical_progression_d12-22_no-steroids-Myeloid-Granulocytic-Neutrophil-Neu_c1-IL1B\|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)	ABCA1 COMT B3GNT5 FCAR FAM149A	3.99e-05	161	105	5	4362fe0c151f49eae7372b9673bac64d980a8389
ToppCell	PND01-03-samps\|World / Age Group, Lineage, Cell class and subclass	RAPGEF5 SPTBN1 UNC13D LDB2 MDN1	3.99e-05	161	105	5	1973b112d8d67aacc02751797d0148e7b53bfa66
ToppCell	Adult-Epithelial-alveolar_epithelial_cell_type_1/2_(AT1/AT2-like)\|Adult / Lineage, Cell type, age group and donor	CAPN12 DUOX1 PTPRG ATP6V1C2 FAM149A	4.23e-05	163	105	5	e819a1d6d28290854aa0672b3a18fa9e293d8f23
ToppCell	kidney_cells-Renal_AKI_(acute_kidney_injury)-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell-Transitional_Principal-Intercalated_Cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	PDE8B ATP6V1C2 CADPS2 SCIN INPP5J	4.75e-05	167	105	5	166b7b4ca0663cde6d88219ee0bcc1988d03dab8
ToppCell	Bronchial_Biopsy-Immune-Mast_cells\|Immune / Tissue, Lineage and Cell class of Lung Cells from 10X	SPTBN1 DUOX2 ALS2 HAS2 SCIN	4.88e-05	168	105	5	45ccc0cb42d21f4853190e8e9ed9a54aefefe738
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Proximal_Tubule_Epithelial_Cell_Segment_1_/_Segment_2\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	MSRA PTPRD ACSM2A BBOX1 ACSM2B	4.88e-05	168	105	5	fa0d251693935116adf633d02b7ec4a295100865
ToppCell	Control-Epithelial_cells-ECM-high_epithelial\|Control / group, cell type (main and fine annotations)	ABCA1 SPTBN1 LDB2 MYO5C DST	5.17e-05	170	105	5	e2023d66e70983c87dacbd6181d3426488d1fc57
ToppCell	10x_3'_v3-spleen_(10x_3'_v3)-lymphocytic-innate_lymphocytic-innate_lymphoid_cell\|spleen_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type	HCN4 DST PTPRD PRMT9 UNC13C	5.17e-05	170	105	5	6c65ddb496030bb479ef346cc37a9d4dfa6b824f
ToppCell	primary_auditory_cortex_(A1C)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_D_(IT_RORB_THEMIS_LINC00507)_2\|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	PTGFRN LDB2 PTPRD UNC13C CADPS2	5.61e-05	173	105	5	8335b77f730ed43fc348a005566e73a103c6774b
ToppCell	facs-Heart-LV-24m-Mesenchymal-valve_cell\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	HCN3 CASQ2 PDE8B BAIAP3 ADAP2	5.77e-05	174	105	5	a0a059bb2a64d7011e206db2ebcdf3eb655a925a
ToppCell	facs-Heart-LV-24m-Mesenchymal-valve_cell\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	HCN3 CASQ2 PDE8B BAIAP3 ADAP2	5.77e-05	174	105	5	7cd6f9103133f8d7b90f9ff4b3b0b078cf554542
ToppCell	Adult-Epithelial-alveolar_epithelial_cell_type_2/Club-like_(AT2/Club-like)-D122\|Adult / Lineage, Cell type, age group and donor	CAPN12 DUOX1 UNC13C ATP6V1C2 FAM149A	6.09e-05	176	105	5	3fee8a367bb9755aca1b7fcc968b08e51b6e9436
ToppCell	356C-Myeloid-Macrophage-FABP4+_Macrophage_3\|Myeloid / Donor, Lineage, Cell class and subclass (all cells)	PRICKLE1 LDB2 PTPRD PTPRG HAS2	6.26e-05	177	105	5	3d955ea938a1d2fb1b6d68d4997fd454bd632dfc
ToppCell	356C-Lymphocytic-CD4_T-cell-Treg_cell_1\|CD4_T-cell / Donor, Lineage, Cell class and subclass (all cells)	CPA5 KBTBD7 DMXL1 BLM MAP3K10	6.26e-05	177	105	5	36b5d29caa9cffbc0284f771a4db71aa72171a89
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Proximal_Tubule_Epithelial_Cell_Segment_3\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	CAPN12 MSRA ACSM2A BBOX1 ACSM2B	6.26e-05	177	105	5	2f81b26be89cc2fd8eafadaf7eae3c6ad6521462
ToppCell	COVID-19-kidney-PCT-S1/S2\|COVID-19 / Disease (COVID-19 only), tissue and cell type	MSRA AKR1B10 ACSM2A BBOX1 ACSM2B	6.43e-05	178	105	5	23a12d3d971b857d5be8e907334d1f6b49eeeb32
ToppCell	COVID-19-kidney-Stressed_EC\|COVID-19 / Disease (COVID-19 only), tissue and cell type	USP13 RAPGEF5 SPTBN1 JMJD1C LDB2	6.60e-05	179	105	5	754f69bac7a1d5137f5141f6193285ccbfe361cb
ToppCell	10x5'-lymph-node_spleen-Myeloid_Mac-Intestinal_macrophages\|lymph-node_spleen / Manually curated celltypes from each tissue	ABCA1 OLFML2B OBSL1 DST ADAP2	6.77e-05	180	105	5	7be7d7a6906fff6dbdecd9cb013d855aba4eda2a
ToppCell	COVID-19-kidney-PLVAP+EC\|COVID-19 / Disease (COVID-19 only), tissue and cell type	USP13 RAPGEF5 SPTBN1 JMJD1C LDB2	6.77e-05	180	105	5	493cf8d1a8f2a1ed2672f394a0338b110fd81d88
ToppCell	COVID-19-kidney-PCT-S2\|COVID-19 / Disease (COVID-19 only), tissue and cell type	CAPN12 PTPRD ACSM2A BBOX1 ACSM2B	6.77e-05	180	105	5	358923e4228035a3e90e2957392089219e90dcd7
ToppCell	renal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Proximal_Tubule_Epithelial_Cell_Segment_1_/_Segment_2\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	MSRA PTPRD ACSM2A BBOX1 ACSM2B	6.77e-05	180	105	5	1363b3254470f6ff98630d1df83a1bdbacc137e0
ToppCell	Control-Epithelial_cells-AT2\|Control / group, cell type (main and fine annotations)	RAPGEF5 DUOX1 PTPRD PTPRG CADPS2	6.77e-05	180	105	5	198b19e7910b4a8cc7e820c525ab357c7f99f578
ToppCell	renal_medulla_nuclei-CKD+DKD_normotensive-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	CAPN12 MSRA PTPRD ACSM2A ACSM2B	6.95e-05	181	105	5	9542c19edc9bd2cba68c01c2a8407705398e3011
ToppCell	COVID-19-Endothelial_cells-Capillary_endothelial_cells\|COVID-19 / group, cell type (main and fine annotations)	RAPGEF5 SPTBN1 LDB2 HERC3 CADPS2	6.95e-05	181	105	5	c5f9c92af1384d9089c65afdf41c6feb8345a3ae
ToppCell	renal_medulla_nuclei-CKD+DKD_normotensive-Epithelial-Proximal_tubule_epithelial_cell\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	CAPN12 MSRA PTPRD ACSM2A ACSM2B	6.95e-05	181	105	5	8f04f8cac5d705dc5f6cf6f4516d6e45b0aa4ae5
ToppCell	COVID-19-kidney-Stressed_PCT\|COVID-19 / Disease (COVID-19 only), tissue and cell type	MSRA AKR1B10 ACSM2A BBOX1 ACSM2B	6.95e-05	181	105	5	6980ea624151da32b7f537f263e40fcb87a02e81
ToppCell	PBMC_fresh-frozen-Severe-critical_progression_d12-22_no-steroids-Myeloid-Dendritic\|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)	COMT OLFML2B PTGFRN RYR1 DST	7.14e-05	182	105	5	9a68d3bd1cc9139de9e9e711c249d47ade826bb1
ToppCell	PBMC_fresh-frozen-Severe-critical_progression_d12-22_no-steroids-Myeloid-Dendritic-conventional_dendritic_cell\|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)	COMT OLFML2B PTGFRN RYR1 DST	7.14e-05	182	105	5	d57d18732aa6fb7b2d430601568f9ba525ac6e3c
ToppCell	COVID-19-kidney-Distal_Epi_Doublet_(PCT)\|COVID-19 / Disease (COVID-19 only), tissue and cell type	SCIN ACSM2A BBOX1 ACSM2B FAM149A	7.14e-05	182	105	5	9d67717a6e13bcb54c1297a3e4e3abf4e51628a3
ToppCell	PBMC_fresh-frozen-Severe-critical_progression_d12-22_no-steroids-Myeloid-Dendritic-conventional_dendritic_cell-DC_c2-CD1C\|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)	COMT OLFML2B PTGFRN RYR1 DST	7.14e-05	182	105	5	c3fb1460160744144aa31afc76c0a4d42ebdeb91
ToppCell	COVID-19-kidney-PCT-S1\|COVID-19 / Disease (COVID-19 only), tissue and cell type	MSRA PTPRD ACSM2A BBOX1 ACSM2B	7.32e-05	183	105	5	6878d14026c3df6aa12e45dfad94b32fa9d9b0b7
ToppCell	5'-Adult-Appendix-Mesenchymal-fibroblastic-Stromal_1_(ADAMDEC1+)\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	ABCA1 PRICKLE1 CCDC39 MRC2 L3MBTL3	7.32e-05	183	105	5	5377b4fbd8fdfe68933b4c0965aa9525f7f31591
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Proximal_Tubule_Epithelial_Cell_Segment_3\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	CAPN12 MSRA ACSM2A BBOX1 ACSM2B	7.32e-05	183	105	5	85446581999cd66b171c4f69b7eb8b0bbbaa8617
ToppCell	droplet-Kidney-nan-21m-Epithelial-epithelial_cell_of_proximal_tubule\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	COMT PIDD1 MSRA ALDH2 ACSM2B	7.32e-05	183	105	5	01e7256c9e0ce53f8e10f3d3a5be15dedd312426
ToppCell	3'_v3-lymph-node_spleen-Lymphocytic_Invariant-Inducer-like-ILC3\|lymph-node_spleen / Manually curated celltypes from each tissue	ABCA1 DST PTPRD MRC2 UNC13C	7.51e-05	184	105	5	479e60f76c191253e23699c9dd7ef7efc08c59ad
ToppCell	renal_medulla_nuclei-CKD+DKD_normotensive\|renal_medulla_nuclei / Celltypes from Cells and Nuclei per compartment and clinical group	PDE8A RAPGEF5 MAP3K5 DST PTPRD	7.51e-05	184	105	5	d2bf0135eb56bb410997dccea39c5ede88a0617f
ToppCell	COVID-19-kidney-PCT-S1/S2\|kidney / Disease (COVID-19 only), tissue and cell type	MSRA PTPRD ACSM2A BBOX1 ACSM2B	7.51e-05	184	105	5	dc71f22583fc54b89b242cbb602f4bbe86f576ec
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Proximal_Tubule_Epithelial_Cell_Segment_3\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	CAPN12 MSRA ACSM2A BBOX1 ACSM2B	7.51e-05	184	105	5	9434731f651820b05335085582960f08fbf895de
ToppCell	Adult-Epithelial-alveolar_epithelial_cell_type_2/Club-like_(AT2/Club-like)\|Adult / Lineage, Cell type, age group and donor	CAPN12 UNC13C ATP6V1C2 CADPS2 FAM149A	7.71e-05	185	105	5	673f0c688ae6984bc8027df2da335787924f4137
ToppCell	COVID-19-Epithelial_cells-Airway_club\|COVID-19 / group, cell type (main and fine annotations)	MYO5C DUOX1 PTPRD CADPS2 FAM149A	7.71e-05	185	105	5	cfe6fd73d817e173fe803bc1683c291d9bcb8608
ToppCell	droplet-Trachea-3m-Mesenchymal-myofibroblast-tracheobronchial_smooth_muscle_cell-smooth_muscle_cell_of_trachea_l20-1\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	OLFML2B SPTBN1 PTGFRN HAS2 ACSM2B	7.71e-05	185	105	5	d5f5866924648a3c14e2596218fd548a31777aa3
ToppCell	Anterior_Cingulate_gyrus_(CgG)-Neuronal-Glutamatergic_Excit\|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	PRICKLE1 RAPGEF5 LDB2 PTPRD CADPS2	7.91e-05	186	105	5	84ba666237c18189d7e7556bd92dd953af733c00
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Proximal_Tubule_Epithelial_Cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	CAPN12 PRICKLE1 PTPRD ACSM2A ACSM2B	7.91e-05	186	105	5	f28d72b47624b69a580b4429e2be560a26898591
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Proximal_Tubule_Epithelial_Cell_Segment_3\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	CAPN12 MSRA PTPRD ACSM2A ACSM2B	7.91e-05	186	105	5	a417e1e21313a7e05951038cdef5ac672a9f727c
ToppCell	Fetal_29-31_weeks-Epithelial-alveolar_epithelial_cell_type_2-D088\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	RAPGEF5 MYO5C PTPRD PTPRG CADPS2	7.91e-05	186	105	5	acfa68a2afb7d2b51c9b469a1965fe5cc5d5e64e
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Degenerative_Proximal_Tubule_Epithelial_Cell\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	MSRA PTPRD ACSM2A BBOX1 ACSM2B	8.11e-05	187	105	5	3ae3b8de1a195d4d5057cf3c64fcdb5f48681ce5
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	CAPN12 MSRA PTPRD ACSM2A ACSM2B	8.11e-05	187	105	5	dcf6475ece5b34d9d58a0d1f51c18acedb19c119
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Proximal_Tubule_Epithelial_Cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	CAPN12 MSRA PTPRD ACSM2A ACSM2B	8.11e-05	187	105	5	9d77ca45f7563bd6f2a0c1be5d99d93ad30983f7
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Epithelial-Proximal_tubule_epithelial_cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	CAPN12 MSRA PTPRD ACSM2A ACSM2B	8.11e-05	187	105	5	f1356273bd3587b6883295edf15cb9cdb706c057
ToppCell	COVID-19-kidney-Mito-rich_PCT\|kidney / Disease (COVID-19 only), tissue and cell type	MSRA PTPRD ACSM2A BBOX1 ACSM2B	8.11e-05	187	105	5	738ec2611b4be6a08eedad16b57fba84e1f11fef
ToppCell	Mid-temporal_gyrus_(MTG)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)\|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	RAPGEF5 LDB2 MYO5C PTPRD CADPS2	8.32e-05	188	105	5	50c1b1d690f0e9443082f2adf4f1b8e9ce4cd337
ToppCell	10x3'2.3-week_14-16-Mesenchymal_myocytic-stroma-muscle_stem_cell\|week_14-16 / cell types per 3 fetal stages;per 3',per 5'	OLFML2B PTGFRN PTPRD PTPRG MRC2	8.32e-05	188	105	5	de6f4889e0c5f39fbbaefd85526f645c6afa09d5
Drug	LY 294002; Up 200; 10uM; HL60; HT_HG-U133A	ABCA1 OBSL1 MRC2 PDE8B HAS2 NFAT5 SULT4A1 FAM149A	3.45e-06	197	104	8	6198_UP
Disease	X-21319 measurement	ACSM2A ACSM2B	1.14e-05	2	100	2	EFO_0800807
Disease	X-11478 measurement	ACSM2A ACSM2B	3.40e-05	3	100	2	EFO_0021242
Disease	drinking behavior	HECTD4 ALDH2	3.40e-05	3	100	2	EFO_0004315
Disease	sick sinus syndrome (implicated_via_orthology)	HCN4 HCN1	3.40e-05	3	100	2	DOID:13884 (implicated_via_orthology)
Disease	alcohol use disorder (implicated_via_orthology)	ACTL6A JMJD1C CHRNB1 RYR1 UNC13C ATP1A3	5.49e-05	195	100	6	DOID:1574 (implicated_via_orthology)
Disease	gout	ABCA1 PTGFRN DST PTPRD ALDH2 ACSM2B	5.65e-05	196	100	6	EFO_0004274
Disease	phenylketonuria (implicated_via_orthology)	DUOX2 DUOX1	6.79e-05	4	100	2	DOID:9281 (implicated_via_orthology)
Disease	3-hydroxyhexanoate measurement	ACSM2A ACSM2B	1.13e-04	5	100	2	EFO_0800378
Disease	chronic kidney disease	HCN1 SPTBN1 HAS2 NFAT5 TBC1D21 L3MBTL3	1.53e-04	235	100	6	EFO_0003884
Disease	indoleacetoylcarnitine measurement	ACSM2A ACSM2B	1.69e-04	6	100	2	EFO_0800106
Disease	very low density lipoprotein cholesterol measurement, cholesteryl esters:total lipids ratio	ABCA1 HECTD4 JMJD1C MSRA NFAT5 L3MBTL3	2.86e-04	264	100	6	EFO_0008317, EFO_0020944
Disease	cups of coffee per day measurement	HECTD4 ATP1A3 TBC1D21	3.41e-04	40	100	3	EFO_0006782
Disease	Colorectal Neoplasms	ABCA1 PAIP2 POLE PTPRD AKR1B10 ALDH2	3.70e-04	277	100	6	C0009404
Disease	22q11 partial monosomy syndrome	COMT JMJD1C	4.03e-04	9	100	2	C3266101
Disease	primary bacterial infectious disease (implicated_via_orthology)	DUOX2 DUOX1	4.03e-04	9	100	2	DOID:0050338 (implicated_via_orthology)
Disease	Asymmetric crying face association	COMT JMJD1C	5.03e-04	10	100	2	C0431406
Disease	22q11 Deletion Syndrome	COMT JMJD1C	5.03e-04	10	100	2	C2936346
Disease	metabolic syndrome	ABCA1 HECTD4 JMJD1C ALDH2 NFAT5	6.08e-04	200	100	5	EFO_0000195
Disease	alcohol consumption measurement, alcohol drinking	HECTD4 ALDH2	7.34e-04	12	100	2	EFO_0004329, EFO_0007878
Disease	age at first birth measurement	HCN1 NUDT9 TBC1D21 ADAP2	7.55e-04	120	100	4	EFO_0009101
Disease	Modic type vertebral endplate changes	PTPRD SCIN	8.66e-04	13	100	2	HP_0030775
Disease	hypothyroidism (implicated_via_orthology)	DUOX2 DUOX1	8.66e-04	13	100	2	DOID:1459 (implicated_via_orthology)
Disease	systolic blood pressure, alcohol drinking	COMT HECTD4 MSRA ALDH2	9.60e-04	128	100	4	EFO_0004329, EFO_0006335
Disease	membranous glomerulonephritis (biomarker_via_orthology)	ABCA1 MAP3K5	1.01e-03	14	100	2	DOID:10976 (biomarker_via_orthology)
Disease	congenital hypothyroidism (implicated_via_orthology)	DUOX2 DUOX1	1.01e-03	14	100	2	DOID:0050328 (implicated_via_orthology)
Disease	third ventricle volume measurement	LDB2 PTPRD	1.16e-03	15	100	2	EFO_0010335
Disease	decreased susceptibility to hepatitis C infection	PTGFRN PTPRD	1.32e-03	16	100	2	EFO_0010101
Disease	DiGeorge Syndrome	COMT JMJD1C	1.32e-03	16	100	2	C0012236
Disease	CONOTRUNCAL ANOMALY FACE SYNDROME	COMT JMJD1C	1.32e-03	16	100	2	C0795907
Disease	Shprintzen syndrome	COMT JMJD1C	1.32e-03	16	100	2	C0220704
Disease	ascending aortic diameter	UNC13D JMJD1C MSRA HAS2	1.34e-03	140	100	4	EFO_0021787
Disease	basophil percentage of leukocytes	OLFML2B SPTBN1 JMJD1C RYR1 L3MBTL3	1.45e-03	243	100	5	EFO_0007992
Disease	myocardial infarction (implicated_via_orthology)	UBD RYR1 MAP3K5	1.48e-03	66	100	3	DOID:5844 (implicated_via_orthology)
Disease	diastolic blood pressure, systolic blood pressure	HCN4 UBD HCN1 PIDD1 CASQ2 MRC2 HAS2 NFAT5	2.02e-03	670	100	8	EFO_0006335, EFO_0006336
Disease	gestational age, birth measurement	OLFML2B PTPRD	2.29e-03	21	100	2	EFO_0005112, EFO_0006921
Disease	Attention Deficit Disorder	COMT PTPRD	2.51e-03	22	100	2	C0041671
Disease	Minimal Brain Dysfunction	COMT PTPRD	2.51e-03	22	100	2	C1321905
Disease	post-traumatic stress disorder symptom measurement	CPA5 MSRA PTPRD	2.76e-03	82	100	3	EFO_0008535
Disease	Anhedonia	COMT ATP1A3	2.99e-03	24	100	2	C0178417
Disease	Attention deficit hyperactivity disorder	COMT PTPRD	2.99e-03	24	100	2	C1263846
Disease	3-hydroxybutyrate measurement	ABCA1 MSRA	3.24e-03	25	100	2	EFO_0010982

Protein segments in the cluster

Peptide	Gene	Start	Entry
AVRDSWNHDMTDFLE	PTPRG	321	P23470
HEMDFDAEWLFENHD	ADNP	836	Q9H2P0
VLAMLAWLDEHVAFE	B3GALT6	136	Q96L58
DAIMVWFVLQLDDEH	PRMT9	406	Q6P2P2
EYWDMALSVDNHVFF	CCIN	26	Q13939
FTVMDHDWLSTNDFA	BAIAP3	1101	O94812
VLASLHEDFLWSMDD	ALS2	1586	Q96Q42
FASDVLDHWADMEKA	ACSM2A	46	Q08AH3
LAVFHDLEGMWEELS	ABCA1	406	O95477
GMVEDWDSFQAILDH	ACTL6A	91	O96019
SSFAILMAHYDVEDW	ADGRE5	531	P48960
ALWDHVTMDDQELGF	ARHGEF4	201	Q9NR80
EDHDALKEDWQFVAM	CHRNB1	451	P11230
ATFLDAWEAMEELVD	AKR1B10	136	O60218
NFWLEDETRFFKMHL	ANGPTL5	261	Q86XS5
DDLWRHFQMAIDDQS	LVRN	541	Q6Q4G3
WAFHSVAEEELLNML	DMXL1	1576	Q9Y485
LDFWDDSIVEFMIHN	ADAP2	66	Q9NPF8
MSSEFLAELHWEDGF	CCDC39	1	Q9UFE4
FQEMLEEEEEHEWFI	PAIP2	61	Q9BPZ3
EHMSFEELLKVFWEN	MSRA	126	Q9UJ68
MVDNRFLVHFDNWDE	L3MBTL3	396	Q96JM7
YFDMEVWALGLHENS	ANO10	336	Q9NW15
DKEELTWEDFHFMLR	DUOX1	911	Q9NRD9
TWEDFHFMLRDHNSE	DUOX1	916	Q9NRD9
MALDEVWDSSHFALQ	OBSL1	166	O75147
AQEAAEFEEMAAWAL	PNMA8A	176	Q86V59
LDWDVAMVHQLSAFQ	FAM86B2	226	P0C5J1
DDTAEHLLELGWFTM	KIAA0100	1946	Q14667
FQMPLESFHSLQEDW	MAP3K10	366	Q02779
LQEDWKLEIQHMFDD	MAP3K10	376	Q02779
VMLDFIDWLTHQEFG	MDN1	1581	Q9NU22
DWTAQFMEAADEALD	MAGED1	661	Q9Y5V3
DAVAAEVFDHVWTNM	FAM149A	451	A5PLN7
IWMLEENLHYVPFED	LGALS16	71	A8MUM7
LAMEFHNSLQDFINW	DST	6596	Q03001
VDIQEDYLMWFLHQA	HERC3	621	Q15034
SHYFLLTEEELTMWE	IPO11	371	Q9UI26
DEAMSLWTHENFEDD	JMJD1C	1781	Q15652
EFTFDDLMRIKTWHF	LDB2	146	O43679
DGDLLQEHWLVEDMF	RABIF	61	P47224
QEHWLVEDMFIFENV	RABIF	66	P47224
HMSIVVEFWLEKDEF	BPIFA3	141	Q9BQP9
YSWIDNFVMEHSDIV	CPA5	146	Q8WXQ8
KEELTWEDFHFMLRD	DUOX2	916	Q9NRD8
WEDFHFMLRDHDSEL	DUOX2	921	Q9NRD8
DAAVDFHRWIAMAAV	DUOX2	1121	Q9NRD8
QLDWDVAMVHQLSAF	FAM86B1	191	Q8N7N1
KFWNETDPEFVIDHM	FCAR	76	P24071
EHFMLEETDWYLLNL	PCYOX1L	116	Q8NBM8
DNAWMETEAVNYHDE	NUDT9	276	Q9BW91
DAWDAFVDLPDLMQH	PDE8A	791	O60658
ITDMFDAWDAFAHLP	PDE8B	841	O95263
LDEMENVFVWEHLQS	MRC2	1306	Q9UBG0
SGWEAETFALEHLEM	POLE	1456	Q07864
RWMHFTEEDQDYLEG	KBTBD7	266	Q8WVZ9
MEWENHTILVEFFLK	OR13C5	1	Q8NGS8
MEWENHTILVEFFLK	OR13C2	1	Q8NGS9
IHQWEEIFHMTYDLA	HCN3	231	Q9P1Z3
LMETDQHIEFFWGAL	HECTD4	3886	Q9Y4D8
NSWKSEAEIDMELFH	NFAT5	486	O94916
TDIIDHSFAVEWMQD	GPN1	191	Q9HCN4
WEEIFHMTYDLASAV	HCN4	401	Q9Y3Q4
MSLDDWQTHYDILAE	PPP1R3A	161	Q16821
EEWADHEDYMTQLLL	PRICKLE1	406	Q96MT3
ASLMFFWEPIDNHIV	B3GNT5	26	Q9BYG0
DVDTLDMVFLDHWKD	COMT	181	P21964
FWMELRDFLLHFDTV	CAPN12	321	Q6ZSI9
VYHEDMTATRLLWDD	HDAC10	6	Q969S8
WEEIFHMTYDLASAV	HCN1	281	O60741
FDDDDDWEDIMHNLA	BLM	561	P54132
ITQDEFLLHMSEDDW	HSD17B8	106	Q92506
FLLHMSEDDWDKVIA	HSD17B8	111	Q92506
ILDHDLIIWFGDMNF	INPP5K	181	Q9BT40
LLHEFVEDWYNQEFM	HAS2	291	Q92819
LDGAHLMQILWYDEE	BBOX1	11	O75936
LDALQMFVFDLHWPE	CADPS2	1016	Q86UW7
WAVMVEADYLIHSFA	MBOAT4	351	Q96T53
MWFDNQIHEADTTED	ATP1A3	381	P13637
EMFETWEDDLNGIHI	CASQ2	256	O14958
WMDISQEFIAHLEAV	RYR1	2966	P21817
RWMHFTEEDQDYLEG	KBTBD6	266	Q86V97
DDLDEQIRHMLFSWA	PIDD1	826	Q9HB75
KDVMLADAQWEFDDT	PTPRD	766	P23468
ADAQWEFDDTTEHDM	PTPRD	771	P23468
QELVDFWMDFLVEAT	MAP3K5	536	Q99683
DPDDMAFDVSWFAVH	PTGFRN	721	Q9P2B2
DLTSFVTHFEWDMAK	ATP6V1C2	96	Q8NEY4
NLMEHTEIDHWLEFS	EPRS1	71	P07814
LFQLMVEHDHETFWL	TBC1D21	171	Q8IYX1
AEDDVMLLDAWEQIF	SCIN	641	Q9Y6U3
LELMNFDWSLFNSIH	RAPGEF5	351	Q92565
EHLFETLSDQMWRQF	TEKT5	321	Q96M29
AAWAMLHDVAYEEAT	OLFML2B	596	Q68BL8
LHQFQADADDIDAWM	SPTBN1	746	Q01082
SDADMDWAVEQAHFA	ALDH2	296	P05091
FASDVLDHWADMEKA	ACSM2B	46	Q68CK6
VLMAQHFDEVWNSEA	RECQL	456	P46063
DALFTDQWSELFMDA	INPP5J	476	Q15735
HVRSEEWDLMTFDAN	UBD	11	O15205
EETPMHWLNDAEFVF	SEMA4G	206	Q9NTN9
WLDENEDVSMEFLHG	UNC13C	1696	Q8NB66
EFWEHRMDSNVLFLK	SULT4A1	181	Q9BR01
LHQFFRDMDDEESWI	SPTAN1	1766	Q13813
DAFHLAGFEVWDVTM	PFAS	1081	O15067
FTHKLLDWLEDAFQM	USP25	266	Q9UHP3
LFEFLHTEMVAELWA	TRAPPC6A	6	O75865
YSSWAEDDHMIIQNE	WEE2	276	P0C1S8
MAHLFGDELEIRWVD	FARS2	251	O95363
QHIEMEPEWEAAFTL	UBR2	526	Q8IWV8
EFEDITNASFHLDMW	UNC13D	191	Q70J99
TNASFHLDMWDLDTV	UNC13D	196	Q70J99
AFNWIIVHMEEPDFA	USP13	686	Q92995
VKEHLEDFEMLSFWL	MYO5C	1431	Q9NQX4