Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	semaphorin receptor activity	PLXNA3 PLXNA4 PLXNA1 PLXNA2	1.70e-07	12	88	4	GO:0017154
GeneOntologyMolecularFunction	hydrolase activity, hydrolyzing O-glycosyl compounds	HEXB MAN1A2 OTOGL CTBS MANEA MGAM2	6.26e-06	103	88	6	GO:0004553
GeneOntologyMolecularFunction	hydrolase activity, acting on glycosyl bonds	HEXB MAN1A2 OTOGL CTBS MANEA MGAM2	4.22e-05	144	88	6	GO:0016798
GeneOntologyMolecularFunction	channel activity	GABRG2 CACNA1C ATP5MG ANO2 CACNA2D4 SLC12A2 SCN10A CLCC1 CACNA2D3	5.08e-04	525	88	9	GO:0015267
GeneOntologyMolecularFunction	passive transmembrane transporter activity	GABRG2 CACNA1C ATP5MG ANO2 CACNA2D4 SLC12A2 SCN10A CLCC1 CACNA2D3	5.15e-04	526	88	9	GO:0022803
GeneOntologyBiologicalProcess	olfactory nerve formation	PLXNA3 PLXNA1	1.76e-05	2	87	2	GO:0021628
GeneOntologyBiologicalProcess	positive regulation of interleukin-3 production	FCER1A SYK	1.76e-05	2	87	2	GO:0032752
GeneOntologyBiologicalProcess	regulation of axon extension involved in axon guidance	PLXNA3 DSCAM PLXNA4	4.72e-05	17	87	3	GO:0048841
GeneOntologyBiologicalProcess	olfactory nerve morphogenesis	PLXNA3 PLXNA1	5.26e-05	3	87	2	GO:0021627
GeneOntologyBiologicalProcess	regulation of interleukin-3 production	FCER1A SYK	5.26e-05	3	87	2	GO:0032672
GeneOntologyBiologicalProcess	dendrite self-avoidance	DSCAM TNN DSCAML1	5.65e-05	18	87	3	GO:0070593
GeneOntologyBiologicalProcess	regulation of cell shape	HEXB PLXNA3 PLXNA4 PRPF40A PLXNA1 PLXNA2	5.76e-05	159	87	6	GO:0008360
GeneOntologyBiologicalProcess	semaphorin-plexin signaling pathway	PLXNA3 PLXNA4 PLXNA1 PLXNA2	6.85e-05	52	87	4	GO:0071526
GeneOntologyBiologicalProcess	interleukin-3 production	FCER1A SYK	1.05e-04	4	87	2	GO:0032632
GeneOntologyBiologicalProcess	axon extension involved in axon guidance	PLXNA3 DSCAM PLXNA4	1.05e-04	22	87	3	GO:0048846
GeneOntologyBiologicalProcess	neuron projection extension involved in neuron projection guidance	PLXNA3 DSCAM PLXNA4	1.05e-04	22	87	3	GO:1902284
GeneOntologyBiologicalProcess	positive regulation of axonogenesis	PLXNA3 DSCAM PLXNA4 PLXNA1 PLXNA2	1.22e-04	114	87	5	GO:0050772
GeneOntologyBiologicalProcess	regulation of cell adhesion	DOCK5 PLXNA3 PRSS2 ZNF609 PTPN11 DSCAM TNN LAMA1 PLXNA4 SYK DSCAML1 PLXNA1 PLXNA2	1.31e-04	927	87	13	GO:0030155
GeneOntologyBiologicalProcess	trigeminal nerve morphogenesis	PLXNA3 PLXNA4	2.61e-04	6	87	2	GO:0021636
GeneOntologyBiologicalProcess	trigeminal nerve structural organization	PLXNA3 PLXNA4	2.61e-04	6	87	2	GO:0021637
GeneOntologyBiologicalProcess	positive regulation of mast cell cytokine production	FCER1A SYK	2.61e-04	6	87	2	GO:0032765
GeneOntologyBiologicalProcess	cell morphogenesis involved in neuron differentiation	PLXNA3 PTPN11 DSCAM TNN PTPRQ LAMA1 PLXNA4 RERE DSCAML1 PLXNA1 PLXNA2	3.02e-04	748	87	11	GO:0048667
GeneOntologyBiologicalProcess	cranial nerve morphogenesis	PLXNA3 PLXNA4 PLXNA1	3.29e-04	32	87	3	GO:0021602
GeneOntologyBiologicalProcess	gonadotrophin-releasing hormone neuronal migration to the hypothalamus	PLXNA3 PLXNA1	3.64e-04	7	87	2	GO:0021828
GeneOntologyBiologicalProcess	hypothalamic tangential migration using cell-axon interactions	PLXNA3 PLXNA1	3.64e-04	7	87	2	GO:0021856
GeneOntologyBiologicalProcess	branchiomotor neuron axon guidance	PLXNA3 PLXNA4	3.64e-04	7	87	2	GO:0021785
GeneOntologyBiologicalProcess	monoatomic anion transmembrane transport	GABRG2 ANO2 SLC12A2 ABCC2 CLCC1	4.77e-04	153	87	5	GO:0098656
GeneOntologyBiologicalProcess	olfactory nerve development	PLXNA3 PLXNA1	4.84e-04	8	87	2	GO:0021553
GeneOntologyBiologicalProcess	sensory perception of mechanical stimulus	HEXB SLC12A2 OTOGL PTPRQ SCN10A USH2A	5.13e-04	238	87	6	GO:0050954
GeneOntologyBiologicalProcess	hypothalamus cell migration	PLXNA3 PLXNA1	6.21e-04	9	87	2	GO:0021855
GeneOntologyBiologicalProcess	hypothalamus gonadotrophin-releasing hormone neuron differentiation	PLXNA3 PLXNA1	6.21e-04	9	87	2	GO:0021886
GeneOntologyBiologicalProcess	hypothalamus gonadotrophin-releasing hormone neuron development	PLXNA3 PLXNA1	6.21e-04	9	87	2	GO:0021888
GeneOntologyBiologicalProcess	regulation of mast cell cytokine production	FCER1A SYK	6.21e-04	9	87	2	GO:0032763
GeneOntologyBiologicalProcess	axonogenesis	PLXNA3 PTPN11 DSCAM TNN LAMA1 PLXNA4 DSCAML1 PLXNA1 PLXNA2	6.35e-04	566	87	9	GO:0007409
GeneOntologyCellularComponent	semaphorin receptor complex	PLXNA3 PLXNA4 PLXNA1 PLXNA2	2.04e-07	13	88	4	GO:0002116
GeneOntologyCellularComponent	nuclear matrix	SF3B1 TCERG1 PSMA6 ENC1 PRPF40A DCAF7	2.80e-05	140	88	6	GO:0016363
GeneOntologyCellularComponent	nuclear periphery	SF3B1 TCERG1 PSMA6 ENC1 PRPF40A DCAF7	8.54e-05	171	88	6	GO:0034399
GeneOntologyCellularComponent	monoatomic ion channel complex	GABRG2 CACNA1C ATP5MG ANO2 CACNA2D4 SCN10A CLCC1 CACNA2D3	1.94e-04	378	88	8	GO:0034702
MousePheno	abnormal retina inner plexiform layer morphology	CACNA2D4 DSCAM DSCAML1 PLXNA2 CLCC1	7.16e-07	33	73	5	MP:0003734
MousePheno	abnormal amacrine cell morphology	DSCAM PLXNA4 DSCAML1 PLXNA2	1.94e-05	31	73	4	MP:0005240
MousePheno	thick retina inner plexiform layer	DSCAM DSCAML1	8.04e-05	3	73	2	MP:0014265
MousePheno	abnormal retina neuronal layer morphology	CACNA2D4 DSCAM LAMA1 MIF4GD PLXNA4 USH2A DSCAML1 PLXNA2 CLCC1 DCAF7	9.25e-05	441	73	10	MP:0006069
Domain	Plexin_cytopl	PLXNA3 PLXNA4 PLXNA1 PLXNA2	4.95e-08	9	85	4	PF08337
Domain	Plexin_cytoplasmic_RasGAP_dom	PLXNA3 PLXNA4 PLXNA1 PLXNA2	4.95e-08	9	85	4	IPR013548
Domain	Plexin	PLXNA3 PLXNA4 PLXNA1 PLXNA2	4.95e-08	9	85	4	IPR031148
Domain	IPT	PLXNA3 PLXNA4 PLXNA1 PLXNA2	6.47e-06	27	85	4	SM00429
Domain	TIG	PLXNA3 PLXNA4 PLXNA1 PLXNA2	1.14e-05	31	85	4	PF01833
Domain	Sema	PLXNA3 PLXNA4 PLXNA1 PLXNA2	1.14e-05	31	85	4	SM00630
Domain	Semap_dom	PLXNA3 PLXNA4 PLXNA1 PLXNA2	1.14e-05	31	85	4	IPR001627
Domain	Sema	PLXNA3 PLXNA4 PLXNA1 PLXNA2	1.14e-05	31	85	4	PF01403
Domain	SEMA	PLXNA3 PLXNA4 PLXNA1 PLXNA2	1.14e-05	31	85	4	PS51004
Domain	PSI	PLXNA3 PLXNA4 PLXNA1 PLXNA2	1.30e-05	32	85	4	PF01437
Domain	IPT	PLXNA3 PLXNA4 PLXNA1 PLXNA2	1.30e-05	32	85	4	IPR002909
Domain	Plexin_repeat	PLXNA3 PLXNA4 PLXNA1 PLXNA2	1.30e-05	32	85	4	IPR002165
Domain	PSI	PLXNA3 PLXNA4 PLXNA1 PLXNA2	4.72e-05	44	85	4	IPR016201
Domain	Rho_GTPase_activation_prot	PLXNA3 PLXNA4 ARHGAP21 PLXNA1 PLXNA2	5.05e-05	88	85	5	IPR008936
Domain	PSI	PLXNA3 PLXNA4 PLXNA1 PLXNA2	5.64e-05	46	85	4	SM00423
Domain	Glycoside_hydrolase_SF	HEXB CTBS MANEA MGAM2	9.87e-05	53	85	4	IPR017853
Domain	VGCC_alpha2	CACNA2D4 CACNA2D3	1.22e-04	4	85	2	PF08473
Domain	-	TCERG1 PRPF40A	1.22e-04	4	85	2	1.10.10.440
Domain	-	GTF2IRD2B GTF2IRD2	1.22e-04	4	85	2	3.90.1460.10
Domain	VDCC_a2/dsu	CACNA2D4 CACNA2D3	1.22e-04	4	85	2	IPR013680
Domain	GTF2I	GTF2IRD2B GTF2IRD2	1.22e-04	4	85	2	PS51139
Domain	GTF2I	GTF2IRD2B GTF2IRD2	1.22e-04	4	85	2	PF02946
Domain	GTF2I	GTF2IRD2B GTF2IRD2	1.22e-04	4	85	2	IPR004212
Domain	VWA_N	CACNA2D4 CACNA2D3	2.03e-04	5	85	2	IPR013608
Domain	VWA_N	CACNA2D4 CACNA2D3	2.03e-04	5	85	2	PF08399
Domain	FF	TCERG1 PRPF40A	3.03e-04	6	85	2	PF01846
Domain	FF	TCERG1 PRPF40A	3.03e-04	6	85	2	SM00441
Domain	FF_domain	TCERG1 PRPF40A	3.03e-04	6	85	2	IPR002713
Domain	FF	TCERG1 PRPF40A	3.03e-04	6	85	2	PS51676
Domain	VWA_3	CACNA2D4 CACNA2D3	5.63e-04	8	85	2	PF13768
Domain	-	PLXNA3 FCER1A DSCAM TNN MMP23B PLXNA4 USH2A DSCAML1 PLXNA1 PLXNA2	8.44e-04	663	85	10	2.60.40.10
Domain	IQ	MYH8 LRRIQ3 SCN10A MYH15	8.57e-04	93	85	4	PS50096
Domain	Ig_E-set	PLXNA3 PLXNA4 PLXNA1 PLXNA2	1.30e-03	104	85	4	IPR014756
Domain	Ig-like_fold	PLXNA3 FCER1A DSCAM TNN MMP23B PLXNA4 USH2A DSCAML1 PLXNA1 PLXNA2	1.36e-03	706	85	10	IPR013783
Domain	ELM2	RCOR3 RERE	1.55e-03	13	85	2	PF01448
Domain	ELM2	RCOR3 RERE	1.55e-03	13	85	2	PS51156
Domain	ELM2_dom	RCOR3 RERE	1.55e-03	13	85	2	IPR000949
Domain	ELM2	RCOR3 RERE	1.55e-03	13	85	2	SM01189
Domain	WW_dom	TCERG1 GALNT9 PRPF40A	1.71e-03	52	85	3	IPR001202
Domain	Myosin_N	MYH8 MYH15	2.07e-03	15	85	2	PF02736
Domain	Myosin_N	MYH8 MYH15	2.07e-03	15	85	2	IPR004009
Domain	Laminin_N	LAMA1 USH2A	2.36e-03	16	85	2	IPR008211
Domain	LAMININ_NTER	LAMA1 USH2A	2.36e-03	16	85	2	PS51117
Domain	Laminin_N	LAMA1 USH2A	2.36e-03	16	85	2	PF00055
Domain	LamNT	LAMA1 USH2A	2.36e-03	16	85	2	SM00136
Domain	Myosin_tail_1	MYH8 MYH15	2.99e-03	18	85	2	PF01576
Domain	Myosin_tail	MYH8 MYH15	2.99e-03	18	85	2	IPR002928
Domain	PUA-like_domain	NIP7 UHRF2	3.33e-03	19	85	2	IPR015947
Domain	Myosin-like_IQ_dom	MYH8 MYH15	3.33e-03	19	85	2	IPR027401
Domain	-	MYH8 MYH15	3.33e-03	19	85	2	4.10.270.10
Domain	RNaseH-like_dom	GTF2IRD2B GTF2IRD2 PIWIL3	3.84e-03	69	85	3	IPR012337
Domain	-	PLXNA3 PLXNA4 IFT80 PLXNA1 PLXNA2 DCAF7	4.13e-03	333	85	6	2.130.10.10
Domain	WD40/YVTN_repeat-like_dom	PLXNA3 PLXNA4 IFT80 PLXNA1 PLXNA2 DCAF7	4.25e-03	335	85	6	IPR015943
Domain	Ricin_B_lectin	GALNT14 GALNT9	5.74e-03	25	85	2	PF00652
Domain	SANT_dom	RCOR3 RERE	6.20e-03	26	85	2	IPR017884
Domain	fn3	DSCAM TNN USH2A DSCAML1	6.41e-03	162	85	4	PF00041
Domain	RICIN	GALNT14 GALNT9	7.17e-03	28	85	2	SM00458
Domain	SANT	RCOR3 RERE	7.17e-03	28	85	2	PS51293
Domain	RICIN_B_LECTIN	GALNT14 GALNT9	7.17e-03	28	85	2	PS50231
Domain	IQ_motif_EF-hand-BS	MYH8 LRRIQ3 SCN10A	8.04e-03	90	85	3	IPR000048
Domain	Ricin_B_lectin	GALNT14 GALNT9	8.20e-03	30	85	2	IPR000772
Domain	Glycos_transf_2	GALNT14 GALNT9	8.20e-03	30	85	2	PF00535
Domain	EGF_LAM_2	LAMA1 USH2A	8.20e-03	30	85	2	PS50027
Domain	Glyco_trans_2-like	GALNT14 GALNT9	8.20e-03	30	85	2	IPR001173
Domain	EGF_LAM_1	LAMA1 USH2A	8.20e-03	30	85	2	PS01248
Pathway	REACTOME_SEMA3A_PLEXIN_REPULSION_SIGNALING_BY_INHIBITING_INTEGRIN_ADHESION	PLXNA3 PLXNA4 PLXNA1 PLXNA2	4.20e-08	9	62	4	MM15030
Pathway	REACTOME_SEMA3A_PAK_DEPENDENT_AXON_REPULSION	PLXNA3 PLXNA4 PLXNA1 PLXNA2	3.28e-07	14	62	4	MM15029
Pathway	REACTOME_SEMA3A_PLEXIN_REPULSION_SIGNALING_BY_INHIBITING_INTEGRIN_ADHESION	PLXNA3 PLXNA4 PLXNA1 PLXNA2	3.28e-07	14	62	4	M7578
Pathway	REACTOME_CRMPS_IN_SEMA3A_SIGNALING	PLXNA3 PLXNA4 PLXNA1 PLXNA2	4.46e-07	15	62	4	MM15031
Pathway	REACTOME_SEMA3A_PAK_DEPENDENT_AXON_REPULSION	PLXNA3 PLXNA4 PLXNA1 PLXNA2	5.93e-07	16	62	4	M16498
Pathway	REACTOME_CRMPS_IN_SEMA3A_SIGNALING	PLXNA3 PLXNA4 PLXNA1 PLXNA2	5.93e-07	16	62	4	M8245
Pathway	REACTOME_NERVOUS_SYSTEM_DEVELOPMENT	PLXNA3 CACNA1C PTPN11 DSCAM PSMA6 LAMA1 SCN10A PLXNA4 DSCAML1 PLXNA1 PLXNA2	3.62e-05	575	62	11	M29853
Pathway	REACTOME_SEMAPHORIN_INTERACTIONS	PLXNA3 PLXNA4 PLXNA1 PLXNA2	7.26e-05	51	62	4	MM14967
Pathway	REACTOME_OTHER_SEMAPHORIN_INTERACTIONS	PLXNA4 PLXNA1 PLXNA2	7.47e-05	19	62	3	M10959
Pathway	KEGG_MEDICUS_REFERENCE_CARDIAC_TYPE_VGCC_RYR_SIGNALING	CACNA1C CACNA2D4 CACNA2D3	1.02e-04	21	62	3	M47950
Pathway	REACTOME_NERVOUS_SYSTEM_DEVELOPMENT	PLXNA3 PTPN11 DSCAM PLXNA4 DSCAML1 PLXNA1 PLXNA2	1.42e-04	261	62	7	MM15676
Pathway	KEGG_MEDICUS_REFERENCE_CA2_ENTRY_VOLTAGE_GATED_CA2_CHANNEL	CACNA1C CACNA2D4 CACNA2D3	1.74e-04	25	62	3	M47948
Pathway	REACTOME_SEMAPHORIN_INTERACTIONS	PLXNA3 PLXNA4 PLXNA1 PLXNA2	1.77e-04	64	62	4	M7923
Pathway	REACTOME_N_GLYCAN_TRIMMING_AND_ELONGATION_IN_THE_CIS_GOLGI	MAN1A2 MANEA	1.89e-04	5	62	2	M27954
Pathway	REACTOME_N_GLYCAN_TRIMMING_AND_ELONGATION_IN_THE_CIS_GOLGI	MAN1A2 MANEA	1.89e-04	5	62	2	MM15670
Pathway	KEGG_HYPERTROPHIC_CARDIOMYOPATHY_HCM	CACNA1C CACNA2D4 PRKAA1 CACNA2D3	4.81e-04	83	62	4	M8728
Pubmed	Chromosome assignment of four plexin A genes (Plxna1, Plxna2, Plxna3, Plxna4) in mouse, rat, Syrian hamster and Chinese hamster.	PLXNA3 PLXNA4 PLXNA1 PLXNA2	4.01e-11	4	89	4	11306810
Pubmed	PlexinA polymorphisms mediate the developmental trajectory of human corpus callosum microstructure.	PLXNA3 PLXNA4 PLXNA1 PLXNA2	4.01e-11	4	89	4	25518740
Pubmed	Semaphorin-6A controls guidance of corticospinal tract axons at multiple choice points.	PLXNA3 PLXNA4 PLXNA1 PLXNA2	1.39e-09	7	89	4	19063725
Pubmed	Increased proximal bifurcation of CA1 pyramidal apical dendrites in sema3A mutant mice.	PLXNA3 PLXNA4 PLXNA1 PLXNA2	1.39e-09	7	89	4	19655386
Pubmed	The expression of plexins during mouse embryogenesis.	PLXNA3 PLXNA4 PLXNA1 PLXNA2	2.78e-09	8	89	4	15661641
Pubmed	Integration of opposing semaphorin guidance cues in cortical axons.	PLXNA3 PLXNA4 PLXNA1 PLXNA2	2.78e-09	8	89	4	22368082
Pubmed	An extracellular biochemical screen reveals that FLRTs and Unc5s mediate neuronal subtype recognition in the retina.	PLXNA3 DSCAM PLXNA4 DSCAML1 PLXNA1 PLXNA2	4.38e-09	52	89	6	26633812
Pubmed	The role of neuropilins in cell signalling.	PLXNA3 PLXNA4 PLXNA1 PLXNA2	5.00e-09	9	89	4	19909241
Pubmed	Plexin A3 and plexin A4 convey semaphorin signals during facial nerve development.	PLXNA3 PLXNA4 PLXNA1 PLXNA2	8.31e-09	10	89	4	18804103
Pubmed	Structural Basis for Plexin Activation and Regulation.	PLXNA4 PLXNA1 PLXNA2	1.62e-08	3	89	3	27397516
Pubmed	Identification of plexin family molecules in mice.	PLXNA3 PLXNA1 PLXNA2	1.62e-08	3	89	3	8806646
Pubmed	Repulsive and attractive semaphorins cooperate to direct the navigation of cardiac neural crest cells.	PLXNA4 PLXNA1 PLXNA2	1.62e-08	3	89	3	18625214
Pubmed	Differential expression of plexin-A subfamily members in the mouse nervous system.	PLXNA3 PLXNA1 PLXNA2	1.62e-08	3	89	3	11241833
Pubmed	Functional loss of semaphorin 3C and/or semaphorin 3D and their epistatic interaction with ret are critical to Hirschsprung disease liability.	PLXNA3 PLXNA4 PLXNA1 PLXNA2	1.95e-08	12	89	4	25839327
Pubmed	PLXNA1 and PLXNA3 cooperate to pattern the nasal axons that guide gonadotropin-releasing hormone neurons.	PLXNA3 PLXNA4 PLXNA1 PLXNA2	1.95e-08	12	89	4	31690636
Pubmed	On and off retinal circuit assembly by divergent molecular mechanisms.	PLXNA3 PLXNA4 PLXNA1 PLXNA2	1.95e-08	12	89	4	24179230
Pubmed	Deletion of Sema3a or plexinA1/plexinA3 causes defects in sensory afferent projections of statoacoustic ganglion neurons.	PLXNA3 PLXNA4 PLXNA1 PLXNA2	1.95e-08	12	89	4	23991118
Pubmed	Transcriptome profiling reveals expression signatures of cranial neural crest cells arising from different axial levels.	PLXNA3 PLXNA4 PLXNA1 PLXNA2	1.95e-08	12	89	4	28407732
Pubmed	Transmembrane semaphorin signalling controls laminar stratification in the mammalian retina.	PLXNA3 PLXNA4 PLXNA1 PLXNA2	1.95e-08	12	89	4	21270798
Pubmed	In-Depth In Vivo Crosslinking in Minutes by a Compact, Membrane-Permeable, and Alkynyl-Enrichable Crosslinker.	GABRG2 PLXNA3 CACNA1C ATP5MG GTF2IRD2B MYH8 C2CD3 SF3B1 TNN PSMA6 NIP7 PLXNA4 GTF2IRD2 MYH15 ABCC2 DNAH8 ARHGAP21 PLXNA2	2.18e-08	1442	89	18	35575683
Pubmed	Functional assembly of accessory optic system circuitry critical for compensatory eye movements.	PLXNA3 PLXNA4 PLXNA1 PLXNA2	2.81e-08	13	89	4	25959730
Pubmed	Plexins are a large family of receptors for transmembrane, secreted, and GPI-anchored semaphorins in vertebrates.	PLXNA3 PLXNA4 PLXNA1 PLXNA2	2.81e-08	13	89	4	10520995
Pubmed	Plexin signaling via off-track and rho family GTPases.	PLXNA3 PLXNA4 PLXNA1 PLXNA2	2.81e-08	13	89	4	11604131
Pubmed	Semaphorin3A, Neuropilin-1, and PlexinA1 are required for lymphatic valve formation.	PLXNA3 PLXNA4 PLXNA1 PLXNA2	2.81e-08	13	89	4	22723296
Pubmed	A midline switch of receptor processing regulates commissural axon guidance in vertebrates.	PLXNA3 PLXNA4 PLXNA1 PLXNA2	3.93e-08	14	89	4	20159958
Pubmed	Determination of cell adhesion sites of neuropilin-1.	PLXNA3 PLXNA1 PLXNA2	6.47e-08	4	89	3	10725340
Pubmed	A family of transmembrane proteins with homology to the MET-hepatocyte growth factor receptor.	PLXNA3 PLXNA1 PLXNA2	6.47e-08	4	89	3	8570614
Pubmed	Allocation of paraventricular and supraoptic neurons requires Sim1 function: a role for a Sim1 downstream gene PlexinC1.	PLXNA3 PLXNA4 PLXNA1 PLXNA2	7.12e-08	16	89	4	17356169
Pubmed	Expression of the semaphorins Sema 3D and Sema 3F in the developing parathyroid and thymus.	PLXNA3 PLXNA4 PLXNA1 PLXNA2	7.12e-08	16	89	4	18489001
Pubmed	Plexin-A3 mediates semaphorin signaling and regulates the development of hippocampal axonal projections.	PLXNA3 PLXNA4 PLXNA1 PLXNA2	9.29e-08	17	89	4	11683995
Pubmed	Semaphorin signaling facilitates cleft formation in the developing salivary gland.	PLXNA3 PLXNA4 PLXNA1 PLXNA2	9.29e-08	17	89	4	17626059
Pubmed	Semaphorin 5A inhibits synaptogenesis in early postnatal- and adult-born hippocampal dentate granule cells.	PLXNA3 PLXNA1 PLXNA2	1.61e-07	5	89	3	25313870
Pubmed	Molecular genetics of successful smoking cessation: convergent genome-wide association study results.	DSCAM LAMA1 MOB3B USH2A DSCAML1 CACNA2D3	2.47e-07	101	89	6	18519826
Pubmed	Expression and function of semaphorin 3A and its receptors in human monocyte-derived macrophages.	PLXNA3 PLXNA1 PLXNA2	3.22e-07	6	89	3	19480842
Pubmed	A semaphorin code defines subpopulations of spinal motor neurons during mouse development.	PLXNA3 PLXNA4 PLXNA1 PLXNA2	4.09e-07	24	89	4	15869472
Pubmed	A radial axis defined by semaphorin-to-neuropilin signaling controls pancreatic islet morphogenesis.	PLXNA3 PLXNA4 PLXNA1 PLXNA2	4.09e-07	24	89	4	28893946
Pubmed	Plexin-neuropilin-1 complexes form functional semaphorin-3A receptors.	PLXNA3 PLXNA1 PLXNA2	5.63e-07	7	89	3	10520994
Pubmed	Expression of Robo/Slit and Semaphorin/Plexin/Neuropilin family members in the developing hypothalamic paraventricular and supraoptic nuclei.	PLXNA3 PLXNA4 PLXNA1 PLXNA2	7.83e-07	28	89	4	18617019
Pubmed	PlexinA2 and semaphorin signaling during cardiac neural crest development.	PLXNA3 PLXNA1 PLXNA2	1.35e-06	9	89	3	11688557
Pubmed	An AUTS2-Polycomb complex activates gene expression in the CNS.	ZNF609 RERE DNAH8 DCAF7	2.77e-06	38	89	4	25519132
Pubmed	Plexin/neuropilin complexes mediate repulsion by the axonal guidance signal semaphorin 3A.	PLXNA1 PLXNA2	6.48e-06	2	89	2	10781943
Pubmed	Nonsense mutation of the stereociliar membrane protein gene PTPRQ in human hearing loss DFNB84.	OTOGL PTPRQ	6.48e-06	2	89	2	20472657
Pubmed	Human down syndrome cell adhesion molecules (DSCAMs) are functionally conserved with Drosophila Dscam[TM1] isoforms in controlling neurodevelopment.	DSCAM DSCAML1	6.48e-06	2	89	2	21645617
Pubmed	DSCAM and DSCAML1 regulate the radial migration and callosal projection in developing cerebral cortex.	DSCAM DSCAML1	6.48e-06	2	89	2	25451118
Pubmed	Mammalian DSCAMs: roles in the development of the spinal cord, cortex, and cerebellum?	DSCAM DSCAML1	6.48e-06	2	89	2	12051741
Pubmed	Structural characterization of a new binding motif and a novel binding mode in group 2 WW domains.	TCERG1 PRPF40A	6.48e-06	2	89	2	17915251
Pubmed	TMEM16B determines cholecystokinin sensitivity of intestinal vagal afferents of nodose neurons.	ANO2 SCN10A	6.48e-06	2	89	2	30843875
Pubmed	Distinct cytoplasmic domains in Plexin-A4 mediate diverse responses to semaphorin 3A in developing mammalian neurons.	PLXNA3 PLXNA4	6.48e-06	2	89	2	24619647
Pubmed	Comparison of TFII-I gene family members deleted in Williams-Beuren syndrome.	GTF2IRD2B GTF2IRD2	6.48e-06	2	89	2	15388857
Pubmed	Disruption of a novel ectodermal neural cortex 1 antisense gene, ENC-1AS and identification of ENC-1 overexpression in hairy cell leukemia.	HEXB ENC1	6.48e-06	2	89	2	15459180
Pubmed	TrkB-dependent EphrinA reverse signaling regulates callosal axon fasciculate growth downstream of Neurod2/6.	PLXNA3 PLXNA4 PLXNA1 PLXNA2	6.57e-06	47	89	4	35462405
Pubmed	Voltage-activated calcium channel expression profiles in mouse brain and cultured hippocampal neurons.	CACNA1C CACNA2D4 CACNA2D3	7.21e-06	15	89	3	20188150
Pubmed	Differential neuronal targeting of a new and two known calcium channel β4 subunit splice variants correlates with their regulation of gene expression.	CACNA1C CACNA2D4 CACNA2D3	7.21e-06	15	89	3	24453333
Pubmed	Optic chiasm presentation of Semaphorin6D in the context of Plexin-A1 and Nr-CAM promotes retinal axon midline crossing.	PLXNA4 PLXNA1 PLXNA2	8.86e-06	16	89	3	22632726
Pubmed	The Functional Proximal Proteome of Oncogenic Ras Includes mTORC2.	DOCK5 SLC12A2 SNX17 OAS1 ABCC2 ARHGAP21 PLXNA1 PLXNA2 FAM83B	1.57e-05	569	89	9	30639242
Pubmed	Irisin Mediates Effects on Bone and Fat via αV Integrin Receptors.	HEXB PRSS2 IARS2 MAN1A2 TCERG1 MRPS18B PRKAA1 MIF4GD OAS1 RERE PRPF40A PLXNA1 CLCC1 DCAF7	1.85e-05	1451	89	14	30550785
Pubmed	Interactions between plexin-A2, plexin-A4, and semaphorin 6A control lamina-restricted projection of hippocampal mossy fibers.	PLXNA4 PLXNA2	1.94e-05	3	89	2	17296555
Pubmed	Fyn-dependent phosphorylation of PlexinA1 and PlexinA2 at conserved tyrosines is essential for zebrafish eye development.	PLXNA1 PLXNA2	1.94e-05	3	89	2	29091353
Pubmed	Plexins promote Hedgehog signaling through their cytoplasmic GAP activity.	PLXNA1 PLXNA2	1.94e-05	3	89	2	36169302
Pubmed	Polymerization of actin does not regulate desensitization in human basophils.	FCER1A SYK	1.94e-05	3	89	2	19150851
Pubmed	Plexin signaling selectively regulates the stereotyped pruning of corticospinal axons from visual cortex.	PLXNA3 PLXNA4	1.94e-05	3	89	2	18523013
Pubmed	Role of transmembrane semaphorin Sema6A in oligodendrocyte differentiation and myelination.	PLXNA4 PLXNA2	1.94e-05	3	89	2	22777942
Pubmed	Isolation and characterisation of GTF2IRD2, a novel fusion gene and member of the TFII-I family of transcription factors, deleted in Williams-Beuren syndrome.	GTF2IRD2B GTF2IRD2	1.94e-05	3	89	2	15100712
Pubmed	Gene conversion-like missense mutations in the human cationic trypsinogen gene and insights into the molecular evolution of the human trypsinogen family.	PRSS3P2 PRSS2	1.94e-05	3	89	2	11073713
Pubmed	The origin of trypsin: evidence for multiple gene duplications in trypsins.	PRSS3P2 PRSS2	1.94e-05	3	89	2	9732462
Pubmed	Molecular cloning and characterization of the human voltage-gated calcium channel alpha(2)delta-4 subunit.	CACNA2D4 CACNA2D3	1.94e-05	3	89	2	12181424
Pubmed	Replacing the PDZ-interacting C-termini of DSCAM and DSCAML1 with epitope tags causes different phenotypic severity in different cell populations.	DSCAM DSCAML1	1.94e-05	3	89	2	27637097
Pubmed	The product of the proto-oncogene c-cbl: a negative regulator of the Syk tyrosine kinase.	FCER1A SYK	1.94e-05	3	89	2	9103201
Pubmed	Myeloid translocation gene 16b is a dual A-kinase anchoring protein that interacts selectively with plexins in a phospho-regulated manner.	PLXNA3 PLXNA1	1.94e-05	3	89	2	20138877
Pubmed	Class 5 transmembrane semaphorins control selective Mammalian retinal lamination and function.	PLXNA3 PLXNA1 PLXNA2	2.08e-05	21	89	3	21835343
Pubmed	The WW domain-containing proteins interact with the early spliceosome and participate in pre-mRNA splicing in vivo.	SF3B1 TCERG1 PRPF40A	3.58e-05	25	89	3	15456888
Pubmed	Role of alpha2/delta subunit in the development of morphine-induced rewarding effect and behavioral sensitization.	CACNA2D4 CACNA2D3	3.87e-05	4	89	2	19596051
Pubmed	Functional interaction between the ubiquitin-specific protease 25 and the SYK tyrosine kinase.	PTPN11 SYK	3.87e-05	4	89	2	19909739
Pubmed	TFII-I gene family during tooth development: candidate genes for tooth anomalies in Williams syndrome.	GTF2IRD2B GTF2IRD2	3.87e-05	4	89	2	17823943
Pubmed	Evolution of general transcription factors.	GTF2IRD2B GTF2IRD2	3.87e-05	4	89	2	23229069
Pubmed	Differential requirement for Plexin-A3 and -A4 in mediating responses of sensory and sympathetic neurons to distinct class 3 Semaphorins.	PLXNA3 PLXNA4	3.87e-05	4	89	2	15721238
Pubmed	GTF2IRD2 from the Williams-Beuren critical region encodes a mobile-element-derived fusion protein that antagonizes the action of its related family members.	GTF2IRD2B GTF2IRD2	3.87e-05	4	89	2	22899722
Pubmed	Semaphorin-plexin signalling genes associated with human breast tumourigenesis.	PLXNA3 PLXNA2	3.87e-05	4	89	2	21925246
Pubmed	PNPT1, MYO15A, PTPRQ, and SLC12A2-associated genetic and phenotypic heterogeneity among hearing impaired assortative mating families in Southern India.	SLC12A2 PTPRQ	3.87e-05	4	89	2	34374074
Pubmed	Kit- and Fc epsilonRI-induced differential phosphorylation of the transmembrane adaptor molecule NTAL/LAB/LAT2 allows flexibility in its scaffolding function in mast cells.	FCER1A SYK	3.87e-05	4	89	2	17993265
Pubmed	Haploinsufficiency of Gtf2i, a gene deleted in Williams Syndrome, leads to increases in social interactions.	GTF2IRD2B GTF2IRD2	3.87e-05	4	89	2	21328569
Pubmed	Coeliac disease-associated risk variants in TNFAIP3 and REL implicate altered NF-kappaB signalling.	PTPN11 SLC12A2 DSCAM MOB3B PLXNA1 CACNA2D3	6.33e-05	265	89	6	19240061
Pubmed	Guidance-cue control of horizontal cell morphology, lamination, and synapse formation in the mammalian outer retina.	PLXNA4 PLXNA2	6.44e-05	5	89	2	22593055
Pubmed	Beta-chemokine receptor CCR5 signals through SHP1, SHP2, and Syk.	PTPN11 SYK	6.44e-05	5	89	2	10747947
Pubmed	LANCL1 binds abscisic acid and stimulates glucose transport and mitochondrial respiration in muscle cells via the AMPK/PGC-1α/Sirt1 pathway.	PRKAA1 LANCL1	6.44e-05	5	89	2	34098144
Pubmed	Critical role for the tyrosine kinase Syk in signalling through the high affinity IgE receptor of mast cells.	FCER1A SYK	6.44e-05	5	89	2	9000133
Pubmed	A central chaperone-like role for 14-3-3 proteins in human cells.	C2CD3 HIVEP2 SLC12A2 TCERG1 PITPNC1 PLK4 ARHGAP21 FOXK1 FAM83B DCAF7	7.15e-05	861	89	10	36931259
Pubmed	Secreted semaphorins control spine distribution and morphogenesis in the postnatal CNS.	PLXNA3 PLXNA4	9.65e-05	6	89	2	20010807
Pubmed	Semaphorin-Plexin signaling influences early ventral telencephalic development and thalamocortical axon guidance.	PLXNA4 PLXNA2	9.65e-05	6	89	2	28438183
Pubmed	Axonal degeneration is regulated by the apoptotic machinery or a NAD+-sensitive pathway in insects and mammals.	PLXNA3 PLXNA4	9.65e-05	6	89	2	20445064
Pubmed	Roles of semaphorin-6B and plexin-A2 in lamina-restricted projection of hippocampal mossy fibers.	PLXNA4 PLXNA2	9.65e-05	6	89	2	20484647
Pubmed	Phosphorylation and recruitment of Syk by immunoreceptor tyrosine-based activation motif-based phosphorylation of tamalin.	PTPN11 SYK	9.65e-05	6	89	2	15173175
Pubmed	FCRL3, an autoimmune susceptibility gene, has inhibitory potential on B-cell receptor-mediated signaling.	PTPN11 SYK	9.65e-05	6	89	2	19843936
Pubmed	SPAP2, an Ig family receptor containing both ITIMs and ITAMs.	PTPN11 SYK	9.65e-05	6	89	2	12051764
Pubmed	CoA Synthase is phosphorylated on tyrosines in mammalian cells, interacts with and is dephosphorylated by Shp2PTP.	PTPN11 SYK	9.65e-05	6	89	2	19763791
Pubmed	Chr21 protein-protein interactions: enrichment in proteins involved in intellectual disability, autism, and late-onset Alzheimer's disease.	GLIPR1 HEXB HIVEP2 MAN1A2 SF3B1 DSCAM TCERG1 KDM4C ENC1 ENPP5 DSCAML1 ARHGAP21	1.06e-04	1285	89	12	35914814
Pubmed	SHP2-interacting transmembrane adaptor protein (SIT), a novel disulfide-linked dimer regulating human T cell activation.	PTPN11 SYK	1.35e-04	7	89	2	10209036
Pubmed	Case-case genome-wide association analysis shows markers differentially associated with schizophrenia and bipolar disorder and implicates calcium channel genes.	CACNA1C LRRIQ3	1.35e-04	7	89	2	21057379
Pubmed	Tyrosine phosphatase SHP-2 mediates C-type lectin receptor-induced activation of the kinase Syk and anti-fungal TH17 responses.	PTPN11 SYK	1.35e-04	7	89	2	25915733
Pubmed	Plexin-A3 and plexin-A4 restrict the migration of sympathetic neurons but not their neural crest precursors.	PLXNA3 PLXNA4	1.35e-04	7	89	2	18262512
Interaction	SEMA5A interactions	PLXNA3 PLXNA4 PLXNA1 PLXNA2	1.12e-08	7	87	4	int:SEMA5A
Interaction	SEMA5B interactions	PLXNA3 PLXNA4 PLXNA1 PLXNA2	4.26e-07	15	87	4	int:SEMA5B
Interaction	SEMA6D interactions	PLXNA3 PLXNA4 PLXNA1 PLXNA2	2.69e-06	23	87	4	int:SEMA6D
Interaction	MS4A2 interactions	PTPN11 FCER1A SYK	4.18e-05	16	87	3	int:MS4A2
Cytoband	12q21.2	GLIPR1 PTPRQ	6.90e-04	20	89	2	12q21.2
Cytoband	5q13	HEXB ENC1	8.37e-04	22	89	2	5q13
Cytoband	1q32.2	RCOR3 PLXNA2	1.26e-03	27	89	2	1q32.2
Cytoband	12p13.3	CACNA1C ANO2	1.56e-03	30	89	2	12p13.3
Cytoband	9p24.1	KDM4C UHRF2	2.00e-03	34	89	2	9p24.1
Cytoband	Ensembl 112 genes in cytogenetic band chr12q21	GLIPR1 OTOGL PTPRQ	2.66e-03	141	89	3	chr12q21
GeneFamily	Plexins	PLXNA3 PLXNA4 PLXNA1 PLXNA2	1.66e-08	9	63	4	683
GeneFamily	Calcium voltage-gated channel subunits	CACNA1C CACNA2D4 CACNA2D3	9.90e-05	26	63	3	253
GeneFamily	Fibronectin type III domain containing	DSCAM TNN PTPRQ USH2A DSCAML1	2.37e-04	160	63	5	555
GeneFamily	Myosin heavy chains	MYH8 MYH15	1.22e-03	15	63	2	1098
GeneFamily	Polypeptide N-acetylgalactosaminyltransferases	GALNT14 GALNT9	2.18e-03	20	63	2	433
GeneFamily	Immunoglobulin like domain containing	FCER1A DSCAM MMP23B DSCAML1	4.59e-03	193	63	4	594
Coexpression	MANNO_MIDBRAIN_NEUROTYPES_HNBML5	GABRG2 PLXNA3 DSCAM TCERG1 ENC1 PLXNA4 LMTK3 PITPNC1 USH2A PLXNA2	3.68e-06	465	88	10	M39066
ToppCell	facs-Lung-Endomucin-24m-Endothelial-Capillary_Type_1_Cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GABRG2 MYH8 OTOGL PTPRQ SCN10A ABCC2 HEPHL1 USH2A	4.95e-10	145	88	8	96712c68ab759d7ade0d912581a1a7c25dc6def8
ToppCell	facs-Marrow-B-cells-24m-Lymphocytic-precursor_B_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MYH8 PTPRQ LAMA1 MYH15 HEPHL1 USH2A DSCAML1 CACNA2D3	1.08e-09	160	88	8	c381ec6be8cf887861cc18f831a20db42f953fe1
ToppCell	facs-Marrow-B-cells-24m-Lymphocytic-pre_B_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MYH8 PTPRQ LAMA1 MYH15 HEPHL1 USH2A DSCAML1 CACNA2D3	1.08e-09	160	88	8	25c8f3d2a6d14ff0ca0b965fce89d3ff22f40585
ToppCell	facs-Lung-24m-Endothelial-capillary_endothelial-capillary_endothelial_cell-capillary_type_1_endothelial_cell\|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	CACNA1C OTOGL PTPRQ SCN10A ABCC2 HEPHL1 USH2A	3.42e-08	162	88	7	bf886e22ff2a20353499004b53f25fb9e6574896
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic-thymocyte\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ANO2 OTOGL PTPRQ LAMA1 MYH15 USH2A DSCAML1	8.19e-08	184	88	7	2cbed6462fea2622871bb7e49b0df3d984239281
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ANO2 OTOGL PTPRQ LAMA1 MYH15 USH2A DSCAML1	8.19e-08	184	88	7	ea7a7e2bac46d4d2c31a5d576b38a032b5335062
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic-proliferating_thymocyte;_DN_to_DP_transition,_dividing_(some_are_Cd8+/_Cd4+,_some_undergoing_VDJ_recombination)\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ANO2 OTOGL PTPRQ LAMA1 MYH15 USH2A DSCAML1	8.19e-08	184	88	7	2b19a8c5f823e00812908b23e66bb4e563278aff
ToppCell	Smart-seq2-blood_(Smart-seq2)-myeloid-myeloid_monocytic-classical_monocyte\|blood_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type	GABRG2 OTOGL SCN10A MYH15 USH2A DNAH8 PIWIL3	8.82e-08	186	88	7	23b8d51d20b05795a73892d3e20e0f9b6a207820
ToppCell	facs-Diaphragm-Limb_Muscle-24m\|Diaphragm / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	HIVEP2 DSCAM OTOGL PLXNA4 MYH15 USH2A	1.08e-06	169	88	6	12bdc709bc000d7f9061ecd9fbd57233eaacb7e2
ToppCell	renal_papilla_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_ascending_limb_epithelial_cell-Ascending_Thin_Limb_Cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	GALNT9 LAMA1 PLXNA4 PITPNC1 DSCAML1 CACNA2D3	2.13e-06	190	88	6	59bbbd2c8d4b7ce46c54ca8022b1557e7e5eee2a
ToppCell	Primary_Visual_cortex_(V1C)-Neuronal-Glutamatergic_Excit\|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	GABRG2 CACNA1C HIVEP2 DSCAM ENC1 CACNA2D3	2.48e-06	195	88	6	2e1df01bf6e4e98e6cd9fb50926e34c5077b8666
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Medullary_Thick_Ascending_Limb_Cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	LAMA1 PLXNA4 DSCAML1 PIWIL3 CACNA2D3	1.65e-05	160	88	5	03b88dc7ad41c6ae443cab7e77ec666340bf432e
ToppCell	COVID-CD8-memory_CD4\|COVID / Condition, Cell_class and T cell subcluster	C2CD3 LRRIQ3 MRPS18B LANCL1 TRAV19	1.75e-05	162	88	5	22b2a32217d357146c117e618813d451510a1801
ToppCell	droplet-Lung-30m-Hematologic-myeloid-myeloid_dendritic_cell-Ccr7+_dendritic\|30m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	DSCAM MMP23B PLA2G4F DSCAML1 F9	2.68e-05	177	88	5	4672cc75225a4a23b298afa8ce439628262519db
ToppCell	renal_medulla_nuclei-CKD+DKD_normotensive-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Medullary_Thick_Ascending_Limb_Cell\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	ZHX3 LAMA1 LMTK3 CACNA2D3 FAM83B	3.06e-05	182	88	5	041bc819e6cf2618bf86bce8dfe2df673f392ba3
ToppCell	COVID-19-kidney-Distal_Epi_Doublet_(PCT)\|COVID-19 / Disease (COVID-19 only), tissue and cell type	GALNT14 ABCC2 DSCAML1 CACNA2D3 FAM83B	3.06e-05	182	88	5	9d67717a6e13bcb54c1297a3e4e3abf4e51628a3
ToppCell	10x5'v1-week_17-19-Myeloid_DC-DC-DC3\|week_17-19 / cell types per 3 fetal stages;per 3',per 5'	GLIPR1 HEXB FCER1A MOB3B CACNA2D3	3.14e-05	183	88	5	c6cac433ea7a3d60728efdc7051e09e01bb3ade5
ToppCell	renal_papilla_nuclei-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	GALNT14 ZHX3 LAMA1 DSCAML1 CACNA2D3	3.40e-05	186	88	5	f0c8de4f6ae9047b9108a47a2af8c5f42bc103b0
ToppCell	TCGA-Pancreas-Primary_Tumor-Pancreatic_Adenocarcinoma-Ductal_Adenocarcinoma-1\|TCGA-Pancreas / Sample_Type by Project: Shred V9	PRKAA1 ENC1 LANCL1 PRPF40A FAM83B	3.40e-05	186	88	5	03db813598b67b1e08f759758a1c2023396921fa
ToppCell	renal_papilla_nuclei-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell-Degenerative_Descending_Thin_Limb_Cell_Type_3\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	GALNT14 ZHX3 LAMA1 DSCAML1 CACNA2D3	3.48e-05	187	88	5	c31130fc2f9f882944b2ba366a034a03f051c4b9
ToppCell	COVID-19-kidney\|COVID-19 / Disease (COVID-19 only), tissue and cell type	GALNT14 ABCC2 DSCAML1 CACNA2D3 FAM83B	3.48e-05	187	88	5	d23aae9419d460b78b1d4092d7acd9108a47cfbe
ToppCell	renal_papilla_nuclei-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	GALNT14 ZHX3 LAMA1 DSCAML1 CACNA2D3	3.57e-05	188	88	5	af740fa78542438fdff627ea1f74f4eee43316be
ToppCell	COVID-19-kidney-DCT\|COVID-19 / Disease (COVID-19 only), tissue and cell type	GALNT14 LAMA1 DSCAML1 CACNA2D3 FAM83B	3.57e-05	188	88	5	1d56cd409793f05cca20757ab26e91f1a1ee67b5
ToppCell	renal_papilla_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_ascending_limb_epithelial_cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	GALNT9 LAMA1 PLXNA4 DSCAML1 CACNA2D3	3.76e-05	190	88	5	1cf023e3c6924d6a06f353d4b62444b6f2fee8a7
ToppCell	COVID-19-kidney-Mito-rich_Distal\|COVID-19 / Disease (COVID-19 only), tissue and cell type	GALNT14 LAMA1 DSCAML1 CACNA2D3 FAM83B	3.85e-05	191	88	5	0965f621ebcd92ccdeb21cc27022180ce3cfe910
ToppCell	PBMC-Control-Myeloid-cDC-cDC-cDC_5\|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)	HEXB FCER1A AIG1 MOB3B CACNA2D3	3.95e-05	192	88	5	dfb9101622f7d2f2c392e850cff07becfc8c655e
ToppCell	PBMC-Control-Myeloid-cDC-cDC-cDC_5\|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	HEXB FCER1A AIG1 MOB3B CACNA2D3	3.95e-05	192	88	5	d39133cf1a20af6f2970188630fc3b27a4cfc9c5
ToppCell	10x3'2.3-week_14-16-Myeloid_DC-DC-DC3\|week_14-16 / cell types per 3 fetal stages;per 3',per 5'	GLIPR1 HEXB ATP5MG FCER1A CACNA2D3	3.95e-05	192	88	5	0e0fbc0bc004dea0db8ccbe81738ab50c0685883
ToppCell	Smart-start-Cell-Wel_seq-Neoplastic-Stem-like-OPC-like-OPC-like-F\|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	PTPRQ ABCC2 USH2A DNAH8 PIWIL3	4.05e-05	193	88	5	315840bc48899f3a36d57b19197509de19716e3d
ToppCell	(010)_cDC\|World / immune cells in Peripheral Blood (logTPM normalization)	FCER1A AIG1 SYK TBC1D9 CACNA2D3	4.25e-05	195	88	5	4aabb3f5ce70100e4d98d7fa9f8d12e84fb9fe3d
ToppCell	renal_medulla_nuclei-CKD+DKD_normotensive-Epithelial\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	GALNT14 AIG1 RERE DSCAML1 CACNA2D3	4.25e-05	195	88	5	6477e6e7be5bd8eb99119a12ae16334ccddecd43
ToppCell	IIF-Myeloid-cDC\|IIF / Disease, Lineage and Cell Type	GLIPR1 HEXB FCER1A SYK CACNA2D3	4.25e-05	195	88	5	81225852a5827e973cb3b1da5c41e93d5407ecb6
ToppCell	VE-mDC2-\|VE / Condition, Cell_class and T cell subcluster	FCER1A SYK MOB3B TBC1D9 CACNA2D3	4.46e-05	197	88	5	6629588819ec31a7e4f33b94b8c035145a5f6c17
ToppCell	VE-mDC2\|VE / Condition, Cell_class and T cell subcluster	FCER1A SYK MOB3B TBC1D9 CACNA2D3	4.46e-05	197	88	5	e3172102ad17c92c3038cad37bf933eb04351048
ToppCell	LPS_anti-TNF-Epithelial_alveolar-AT_1-Differentiating_AT1\|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type	PTPRQ IFT80 DSCAML1 PLXNA1 CACNA2D3	4.68e-05	199	88	5	d43c605a4ff221cf78d91678c15d2ad20f831c7f
ToppCell	LPS_IL1RA_TNF-Epithelial_alveolar-AT_1-Differentiating_AT1\|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type	PTPRQ IFT80 DSCAML1 PLXNA1 CACNA2D3	4.79e-05	200	88	5	ddfb1f006365bf16203ee49f20200f68220cc288
ToppCell	MS-IIF-Myeloid-cDC\|IIF / Disease, condition lineage and cell class	GLIPR1 HEXB FCER1A SYK CACNA2D3	4.79e-05	200	88	5	620a82805619d113182d59740670c9f9b93ee924
ToppCell	MS-Multiple_Sclerosis-Myeloid-cDC\|Multiple_Sclerosis / Disease, condition lineage and cell class	GLIPR1 HEXB FCER1A SYK CACNA2D3	4.79e-05	200	88	5	d9e6c344c59544c87bc13d1e866491da432c9c1b
ToppCell	Entopeduncular-Macroglia-OLIGODENDROCYTE-O2-Trf-Oligodendrocyte.Trf.Cldn11_(Cldn11)\|Entopeduncular / BrainAtlas - Mouse McCarroll V32	CACNA2D4 MRPS18B SYK PLK4	5.83e-05	106	88	4	5e01b9dd76a2f5904100de603310e6c0a553fbda
ToppCell	Entopeduncular-Macroglia-OLIGODENDROCYTE-O2-Trf-Oligodendrocyte.Trf.Cldn11_(Cldn11)-\|Entopeduncular / BrainAtlas - Mouse McCarroll V32	CACNA2D4 MRPS18B SYK PLK4	5.83e-05	106	88	4	be9de0f664395079fef9f3bbdffa651ea6f58be2
ToppCell	LPS-IL1RA-Lymphocytic_NKT-T_cells-Erythroid\|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	GSTT1 PITPNC1 MMD TRAV19	1.21e-04	128	88	4	c2045f052cc713e52312eb015825711576fcb6c5
ToppCell	frontal_cortex-Neuronal-glutamatergic_neuron-L6_CT-L6_CT_ALM_Nxph2_Sla\|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	GALNT9 MYH15 PITPNC1 HCRTR1	1.45e-04	134	88	4	6d97fa07f55ae20c17b9d5262e893957cccc6dba
ToppCell	RA-06._Ventricular_Cardiomyocyte_II\|World / Chamber and Cluster_Paper	CACNA1C MYH8 OTOGL RHBDL3	1.49e-04	135	88	4	6121b1d30d05b7d476661b932f51191da09dfeeb
ToppCell	renal_papilla_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell-Descending_Thin_Limb_Cell_Type_1\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	GALNT14 LAMA1 DSCAML1 CACNA2D3	1.49e-04	135	88	4	8521107817df49efd9a2e81078c8535ed33e729c
ToppCell	PBMC-Control-Myeloid-cDC-cDC-cDC_2\|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	ATP5MG FCER1A CACNA2D3 FAM83B	1.57e-04	137	88	4	86c32cd26fe3b23c1dcd8ace580231c5a6ec6d9e
ToppCell	PBMC-Control-Myeloid-cDC-cDC-cDC_2\|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)	ATP5MG FCER1A CACNA2D3 FAM83B	1.57e-04	137	88	4	8989103606b15dff300e44c1590cd867b3cf7833
ToppCell	renal_papilla_nuclei-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_ascending_limb_epithelial_cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	ZHX3 LAMA1 DSCAML1 CACNA2D3	1.62e-04	138	88	4	a88c3ae56b0af60f6e87cabade4f21e2bbb336f2
ToppCell	LPS-IL1RA-Lymphocytic_NKT-iNKT/MAIT-T-cells\|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	SCN10A HEPHL1 MMD PIWIL3	1.66e-04	139	88	4	ecc2a6ecc27748c50885cd4f0ad8a8cd1252aee6
ToppCell	facs-Heart-Unknown-3m-Endothelial-endothelial_cell_of_coronary_artery\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	OTOGL PTPRQ LAMA1 F9	1.76e-04	141	88	4	4aa4b3476dc5abefbd348353cfe711cd5fe3d52f
ToppCell	facs-Heart-Unknown-3m-Endothelial-coronary_vascular_endothelial_cell\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	OTOGL PTPRQ LAMA1 F9	1.76e-04	141	88	4	e40c6f1b7fbaa46b3eaa55f1b37ef360b04370a8
ToppCell	facs-Heart-Unknown-3m-Endothelial\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	OTOGL PTPRQ LAMA1 F9	1.81e-04	142	88	4	759fbbd15b4fb313bd6269b7f087edafebd530ef
ToppCell	PBMC_fresh-frozen-Mild-Moderate_convalescent_d36-51-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD4_c14-MKI67-CCL5_h\|Mild-Moderate_convalescent_d36-51 / Compartment, severity and other cell annotations on 10x 3' data (130k)	GALNT9 PLK4 PIWIL3 PLXNA1	1.90e-04	144	88	4	bdd6d00b2d1c9dad989df82367a60e8be79de816
ToppCell	frontal_cortex-Neuronal-GABAergic_neuron-Sst-Sst_Chrna2_Glra3\|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	GALNT14 MYH8 PITPNC1 CACNA2D3	2.06e-04	147	88	4	50e86860a94be103092c40e39a172eac92372f0d
ToppCell	COVID-19-kidney-Technical/muscle_(Mes)\|COVID-19 / Disease (COVID-19 only), tissue and cell type	GABRG2 DSCAM USH2A DNAH8	2.12e-04	148	88	4	d6ac5972267254651dfbe16bb4e9a62228093cc7
ToppCell	LPS-antiTNF-Endothelial-Epi-like-Gen_Cap\|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	PTPRQ ABCC2 DSCAML1 CACNA2D3	2.23e-04	150	88	4	9cb3332924bd67c966873343c14445e30d3f384f
ToppCell	PBMC-Mild-Myeloid-cDC-cDC-cDC_3\|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)	FCER1A MOB3B TBC1D9 CACNA2D3	2.52e-04	155	88	4	ab539c04f10276ae919d82b1c75f99a84eb695bf
ToppCell	PBMC-Mild-Myeloid-cDC-cDC-cDC_3\|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	FCER1A MOB3B TBC1D9 CACNA2D3	2.52e-04	155	88	4	9a27558c457f05808af07190b7a5006b047f1d58
ToppCell	COVID-19-lung-Mesothelial\|lung / Disease (COVID-19 only), tissue and cell type	GALNT9 PTPRQ DSCAML1 CACNA2D3	2.59e-04	156	88	4	e1f563869b3bf997eaa2e756e31b53db1a478903
ToppCell	droplet-Liver-Hepatocytes-24m-Myeloid\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SLC12A2 SYK PLA2G4F PLXNA1	2.65e-04	157	88	4	ec433d2fe827abdb647be4176c231b7052482b6f
ToppCell	PBMC-Severe-Myeloid-cDC-cDC-cDC_1\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	FCER1A MOB3B TBC1D9 CACNA2D3	2.65e-04	157	88	4	e9d0300361b06aec3c216f8af15f09e14b12a4da
ToppCell	PBMC-Severe-Myeloid-cDC-cDC-cDC_1\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)	FCER1A MOB3B TBC1D9 CACNA2D3	2.71e-04	158	88	4	e9657d8960d499832f9f9b45b5a6f4388551b7e1
ToppCell	PBMC-Control-Myeloid-cDC-cDC-cDC_1\|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)	GABRG2 FCER1A MOB3B OAS1	2.71e-04	158	88	4	216b3f482daa2d0d7fcaf5a8559e3ccbdb8e110d
ToppCell	PBMC-Control-Myeloid-cDC-cDC-cDC_1\|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	GABRG2 FCER1A MOB3B OAS1	2.71e-04	158	88	4	9712bb8b1bacb8a38c99a22bc2babec5d5160e2a
ToppCell	Posterior_cortex-Neuronal-Inhibitory-iN2(Gad1Gad2)-Cplx3-Inhibitory_Neuron.Gad1Gad2.Cplx3-Npy_(Cortical_subplate_interneuron)\|Posterior_cortex / BrainAtlas - Mouse McCarroll V32	MYH8 ABCC2 FAM83B	2.76e-04	64	88	3	28acc0d394b8cd2fd93ae5e0801f0ff1dd4b16ac
ToppCell	Club-club-7\|World / Class top	KDM4C MRPS18B FAM83B	2.76e-04	64	88	3	df413c5328966480479c41826461c4d817fbe33d
ToppCell	Posterior_cortex-Neuronal-Inhibitory-iN2(Gad1Gad2)-Cplx3-Inhibitory_Neuron.Gad1Gad2.Cplx3-Npy_(Cortical_subplate_interneuron)-\|Posterior_cortex / BrainAtlas - Mouse McCarroll V32	MYH8 ABCC2 FAM83B	2.76e-04	64	88	3	61414e0fa2242f156f0f45f8733b831b7f965dd8
ToppCell	droplet-Kidney-nan-3m-Myeloid-nan\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GLIPR1 HEXB F9 TBC1D9	2.78e-04	159	88	4	bea6e96ba40ebfc1e38687bfa1c61fe227c5a84d
ToppCell	droplet-Liver-Hepatocytes-24m-Myeloid-Kupffer_cell\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SLC12A2 SYK PLA2G4F PLXNA1	3.06e-04	163	88	4	8dc0128eeede933537e3bcc5d6ec0322711552f3
ToppCell	droplet-Liver-Hepatocytes-24m-Myeloid-Kupffer_cell\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SLC12A2 SYK PLA2G4F PLXNA1	3.06e-04	163	88	4	fd243ca223079033be480a24817a399f281fa4d4
ToppCell	COVID-19-lung-Mesothelial\|COVID-19 / Disease (COVID-19 only), tissue and cell type	GALNT9 PTPRQ DSCAML1 CACNA2D3	3.13e-04	164	88	4	83303e2ba52008391b8dc3fae8225ab5bcb20063
ToppCell	Dendritic_Cells-Donor_02\|World / lung cells shred on cell class, cell subclass, sample id	GLIPR1 FCER1A TMEM14EP CACNA2D3	3.27e-04	166	88	4	fbeb74b98b58085de323f744b18d4a8f7b22d5d4
ToppCell	Hippocampus-Neuronal-Inhibitory-iN2(Gad1Gad2)-Bcl11b-Inhibitory_Gad1Gad2_Id2.Bcl11b_(Interneuron,_Neurogliaform2)\|Hippocampus / BrainAtlas - Mouse McCarroll V32	MYH8 OTOGL FAM83B	3.31e-04	68	88	3	cfd75c373e10b3761666ccd445ba74755efeb95f
ToppCell	Hippocampus-Neuronal-Inhibitory-iN2(Gad1Gad2)-Bcl11b\|Hippocampus / BrainAtlas - Mouse McCarroll V32	MYH8 OTOGL FAM83B	3.31e-04	68	88	3	c25fb921dc83eecdc337353894829ae6b5192353
ToppCell	Hippocampus-Neuronal-Inhibitory-iN2(Gad1Gad2)-Bcl11b-Inhibitory_Gad1Gad2_Id2.Bcl11b_(Interneuron,_Neurogliaform2)-\|Hippocampus / BrainAtlas - Mouse McCarroll V32	MYH8 OTOGL FAM83B	3.31e-04	68	88	3	712f5f4d3a1e0c0db1a340332876206b93bdac31
ToppCell	droplet-Lung-LUNG-30m-Myeloid-dendritic_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DSCAM PLA2G4F DSCAML1 F9	3.43e-04	168	88	4	0e8b0e6399c6c82c9c0e546f7316f902de0765d3
ToppCell	droplet-Bladder-BLADDER-1m-Epithelial-basal_bladder_epithelial_cell_(Krt5+Krt14+)\|Bladder / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CACNA2D4 ABCC2 PRPF40A DSCAML1	3.43e-04	168	88	4	ca65321259711321c175ede67bd67a47aad81d7a
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial-Afferent_/_Efferent_Arteriole_Endothelial_Cell\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	ANO2 NIP7 HEPHL1 PLXNA2	3.50e-04	169	88	4	c7fc3a8c44f07c557b60d469717b66e2f5863d38
ToppCell	Ionocyte\|World / Class top	HEXB GALNT14 SLC12A2 PLXNA4	3.58e-04	170	88	4	d2e592f2a679e6a8d32f2b752d9a3c493e50ced4
ToppCell	Healthy/Control-Plasmablast\|World / Disease group and Cell class	GALNT14 GALNT9 MANEA HEPHL1	3.75e-04	172	88	4	d3bfcf5d936152b71cd90f955f9331709edd979e
ToppCell	Posterior_cortex-Neuronal-Excitatory-eN2(Slc17a7_Slc17a6)-Tshz2-Excitatory_Neuron.Slc17a7-Slc17a6.Tshz2-Nnat_(Presubiculum,_Col5a2+)\|Posterior_cortex / BrainAtlas - Mouse McCarroll V32	GLIPR1 TNN PTPRQ	3.75e-04	71	88	3	3f7ab70a5451043019f6e56c16ab95182ff44a15
ToppCell	Posterior_cortex-Neuronal-Excitatory-eN2(Slc17a7_Slc17a6)-Tshz2-Excitatory_Neuron.Slc17a7-Slc17a6.Tshz2-Nnat_(Presubiculum,_Col5a2+)-\|Posterior_cortex / BrainAtlas - Mouse McCarroll V32	GLIPR1 TNN PTPRQ	3.75e-04	71	88	3	f0af76191cb0e29abf6e7d1a6f5a0df1ad837ce7
ToppCell	Ionocyte-iono-2\|World / Class top	HEXB GALNT14 SLC12A2 PLXNA4	3.83e-04	173	88	4	e5ec28ccc5e048fd98de4c876e5c53b866b66228
ToppCell	facs-Diaphragm-Limb_Muscle-24m-Mesenchymal\|Diaphragm / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	HIVEP2 OTOGL MMP23B USH2A	3.83e-04	173	88	4	66f37c1437705734b20601656fa4aa1d92ca30be
ToppCell	facs-Diaphragm-Limb_Muscle-24m-Mesenchymal-nan\|Diaphragm / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	HIVEP2 OTOGL MMP23B USH2A	3.83e-04	173	88	4	649b08a409095592cccf31883be69c754411280d
ToppCell	ASK452-Immune-B_cell\|ASK452 / Donor, Lineage and Cell class of Lung cells from Dropseq	PTPN11 PRKAA1 MIF4GD PLXNA4	3.91e-04	174	88	4	69723f5666abc3af5f0431901a60246c9915ef81
ToppCell	droplet-Lung-LUNG-30m-Myeloid-Ccr7+_Dendritic\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DSCAM PLA2G4F DSCAML1 F9	4.00e-04	175	88	4	91cb819a1786020713b7e64480de0545380daae9
ToppCell	Healthy_donor-Plasmablast\|World / disease group, cell group and cell class (v2)	GALNT14 GALNT9 MANEA HEPHL1	4.00e-04	175	88	4	5293e00fda63a291aa393bdf82ebd4b80265049f
ToppCell	5'-GW_trimst-2-SmallIntestine-Epithelial-mature_enterocytic-Paneth\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	PRSS2 SLC12A2 PLA2G4F MGAM2	4.00e-04	175	88	4	bffa623511ceb0b9bf76d87f9a10cfadfe0e940f
ToppCell	facs-Marrow-B-cells-24m\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PTPRQ MYH15 USH2A CACNA2D3	4.00e-04	175	88	4	887e75fc90e59a6394d62f3c048a9cfdf6707725
ToppCell	facs-Marrow-B-cells-24m-Lymphocytic\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PTPRQ MIF4GD USH2A CACNA2D3	4.08e-04	176	88	4	c6484334187f64cd00cd35e77d8ae436556b4260
ToppCell	3'-Child04-06-SmallIntestine-Hematopoietic-B_cells-FCRL4+_Memory_B\|Child04-06 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	GLIPR1 SYK DNAH8 TBC1D9	4.08e-04	176	88	4	8c5218aa188ea5a4d3c749b3c8a6596835cbdc87
ToppCell	Brain_organoid-organoid_Velasco_nature-3_mon-Neuronal-Immature_Interneurons\|3_mon / Sample Type, Dataset, Time_group, and Cell type.	DOCK5 GALNT14 DSCAML1 CACNA2D3	4.08e-04	176	88	4	62870115e31170c8b42eec57c709e0fe32388b37
ToppCell	droplet-Kidney-nan-21m-Lymphocytic-nan\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PRSS2 GALNT9 RHBDL3 DNAH8	4.08e-04	176	88	4	feafc757e7aa4f17128ff34886beb2fd3461c9ea
ToppCell	3'_v3-lymph-node_spleen-Myeloid_Dendritic-DC2\|lymph-node_spleen / Manually curated celltypes from each tissue	DOCK5 FCER1A LAMA1 CACNA2D3	4.08e-04	176	88	4	72a3bbab0540ae3e3c94b9573cdb9298a024dbc4
ToppCell	10x3'2.3-week_17-19-Myeloid_DC-DC-DC3\|week_17-19 / cell types per 3 fetal stages;per 3',per 5'	GLIPR1 HEXB MOB3B CACNA2D3	4.08e-04	176	88	4	7762e5d7c11756da605a604a289216bb53e25869
ToppCell	5'-Adult-Distal_Rectal-Epithelial-goblet-Goblet_cell\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	SLC12A2 LANCL1 DSCAML1 PLXNA1	4.17e-04	177	88	4	e1e45956887371b1c18f1eb479dd930031497520
ToppCell	Control-Epithelial_alveolar-AT_1-Differentiating_AT1\|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	PTPRQ IFT80 DSCAML1 CACNA2D3	4.17e-04	177	88	4	9af14a056eb6d88c6f11b09f6d4c0d3448d647d5
ToppCell	droplet-Liver-LIVER_NPC-30m-Endothelial-nan\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ZHX3 ENC1 PLXNA4 DNAH8	4.35e-04	179	88	4	025d414ec88d5680d99c8173e70ee3bb0b694f74
ToppCell	ASK452-Immune-B_cell\|Immune / Donor, Lineage and Cell class of Lung cells from Dropseq	PTPN11 PRKAA1 MIF4GD PLXNA4	4.35e-04	179	88	4	c3cf49c069e66db16d2fce1de4c52a4c4fe7e832
ToppCell	human_hepatoblastoma-Tumor_cells-T6\|Tumor_cells / Sample and Cell Type and Tumor Cluster (all cells)	LRRIQ3 HIVEP2 SLC12A2 CACNA2D3	4.35e-04	179	88	4	14fc8ccb6b215063d747643f47d780d2b237eb67
Disease	head and neck cancer (is_implicated_in)	GSTT1 KDM4C	5.14e-05	4	87	2	DOID:11934 (is_implicated_in)
Disease	age at menarche	DSCAM KDM4C GALNT9 OSBP2 RERE MMD PRPF40A DSCAML1 FAM83B	6.50e-05	594	87	9	EFO_0004703
Disease	coagulation factor IXAB measurement	SNX17 F9	8.54e-05	5	87	2	EFO_0020264
Disease	autosomal dominant hyaline body myopathy (implicated_via_orthology)	MYH8 MYH15	3.81e-04	10	87	2	DOID:0111269 (implicated_via_orthology)
Disease	distal arthrogryposis type 2B3 (implicated_via_orthology)	MYH8 MYH15	3.81e-04	10	87	2	DOID:0111602 (implicated_via_orthology)
Disease	distal arthrogryposis type 1 (implicated_via_orthology)	MYH8 MYH15	3.81e-04	10	87	2	DOID:0111596 (implicated_via_orthology)
Disease	dilated cardiomyopathy 1S (implicated_via_orthology)	MYH8 MYH15	3.81e-04	10	87	2	DOID:0110454 (implicated_via_orthology)
Disease	congenital myopathy 6 (implicated_via_orthology)	MYH8 MYH15	3.81e-04	10	87	2	DOID:0080719 (implicated_via_orthology)
Disease	inclusion body myositis (implicated_via_orthology)	MYH8 MYH15	3.81e-04	10	87	2	DOID:3429 (implicated_via_orthology)
Disease	distal arthrogryposis type 2A (implicated_via_orthology)	MYH8 MYH15	3.81e-04	10	87	2	DOID:0111605 (implicated_via_orthology)
Disease	familial hypertrophic cardiomyopathy (implicated_via_orthology)	MYH8 MYH15	3.81e-04	10	87	2	DOID:0080326 (implicated_via_orthology)
Disease	Cocaine-Related Disorders	GABRG2 MANEA DNAH8 HCRTR1	4.05e-04	117	87	4	C0236736
Disease	Paranoia	MANEA DNAH8	4.65e-04	11	87	2	C1456784
Disease	Shortened QT interval	CACNA1C SCN10A	4.65e-04	11	87	2	C0151879
Disease	urate measurement, bone density	GLIPR1 DOCK5 GABRG2 DSCAM GALNT9 PLXNA4 USH2A DNAH8	4.89e-04	619	87	8	EFO_0003923, EFO_0004531
Disease	Cocaine Abuse	GABRG2 MANEA DNAH8 HCRTR1	5.53e-04	127	87	4	C0009171
Disease	generalized epilepsy with febrile seizures plus (implicated_via_orthology)	GABRG2 SCN10A	5.56e-04	12	87	2	DOID:0060170 (implicated_via_orthology)
Disease	distal myopathy (implicated_via_orthology)	MYH8 MYH15	5.56e-04	12	87	2	DOID:11720 (implicated_via_orthology)
Disease	myotonia congenita (implicated_via_orthology)	MYH8 MYH15	5.56e-04	12	87	2	DOID:2106 (implicated_via_orthology)
Disease	restrictive cardiomyopathy (implicated_via_orthology)	MYH8 MYH15	6.56e-04	13	87	2	DOID:397 (implicated_via_orthology)
Disease	triacylglycerol 48:4 measurement	DSCAM F9	7.64e-04	14	87	2	EFO_0010407
Disease	Cocaine Dependence	GABRG2 MANEA DNAH8 HCRTR1	7.75e-04	139	87	4	C0600427
Disease	Down syndrome (implicated_via_orthology)	DSCAM DSCAML1	8.80e-04	15	87	2	DOID:14250 (implicated_via_orthology)
Disease	distal arthrogryposis (implicated_via_orthology)	MYH8 MYH15	8.80e-04	15	87	2	DOID:0050646 (implicated_via_orthology)
Disease	triacylglycerol 50:5 measurement	CACNA2D4 SNX17	1.00e-03	16	87	2	EFO_0010412
Disease	resting heart rate	CACNA1C ZHX3 SCN10A ARHGAP21	1.00e-03	149	87	4	EFO_0004351
Disease	R-warfarin measurement	DOCK5 CACNA1C HIVEP2 SCN10A ARHGAP21	1.14e-03	265	87	5	EFO_0803324
Disease	Non-alcoholic Fatty Liver Disease	GSTT1 LAMA1 ABCC2	1.18e-03	70	87	3	C0400966
Disease	Nonalcoholic Steatohepatitis	GSTT1 LAMA1 ABCC2	1.18e-03	70	87	3	C3241937
Disease	alpha-tocopherol measurement	KDM4C USH2A	1.58e-03	20	87	2	EFO_0007898
Disease	dilated cardiomyopathy (implicated_via_orthology)	MYH8 PTPN11 MYH15	1.73e-03	80	87	3	DOID:12930 (implicated_via_orthology)
Disease	gestational age, birth measurement	HCRTR1 CACNA2D3	1.74e-03	21	87	2	EFO_0005112, EFO_0006921
Disease	daytime rest measurement	ZHX3 HIVEP2 DSCAM RERE HCRTR1	1.83e-03	295	87	5	EFO_0007828
Disease	triacylglycerol 48:3 measurement	CACNA2D4 SNX17	1.91e-03	22	87	2	EFO_0010406
Disease	Brugada Syndrome (disorder)	CACNA1C SCN10A	2.27e-03	24	87	2	C1142166
Disease	Impaired glucose tolerance	SLC12A2 PRKAA1	2.47e-03	25	87	2	C0271650
Disease	Neurodevelopmental Disorders	PTPN11 DSCAM CACNA2D3	2.65e-03	93	87	3	C1535926

Protein segments in the cluster

Peptide	Gene	Start	Entry
RNWDVYKVIYYKDGE	FCER1A	136	P12319
WIIYAYDREMIYPKL	AIG1	106	Q9NVV5
KLLYQEWARYGVFYK	ANO2	331	Q9NQ90
LWDKDQRAPYYNYKD	CTBS	306	Q01459
TYSKPRLATFWYYAK	ATP5MG	21	O75964
KRKEIYKYEAPWTVY	DCAF7	6	P61962
PDKTIASLVKYYYSW	RCOR3	116	Q9P2K3
YEYRWQDDLKYKKPT	MOB3B	96	Q86TA1
RDQVKRYYSVVYPGW	GLIPR1	211	P48060
AKSPLMYEWYQEYYV	LANCL1	201	O43813
VKAYIPDATWYDYET	MGAM2	726	Q2M2H8
VKWYAPECINYYKFS	SYK	536	P43405
KWYLENVYPEMRVYN	GALNT9	446	Q9HCQ5
NYKEDYYLTPERLWI	LMTK3	291	Q96Q04
SDNYIEPHYKEWYRV	FAM83B	16	Q5T0W9
YKWLPVYKPEVVAAY	MYH8	131	P13535
IPNYKSWVERYYADI	PLXNA1	1806	Q9UIW2
AKDIPSYKSWVERYY	PLXNA2	1801	O75051
SYKSWVERYYADIAK	PLXNA2	1806	O75051
IPNYKSWVERYYRDI	PLXNA3	1781	P51805
AKDIPSYKNWVERYY	PLXNA4	1801	Q9HCM2
VDLDKRLQYYRYPWS	PDZD9	156	Q8IXQ8
YKKEDVPERWHYKYN	ENPP5	296	Q9UJA9
EHWNKKLQPYYYPTD	DNAH8	2406	Q96JB1
YGIYTKVSRYVNWIK	F9	441	P00740
PRYLDYEDLERKYWK	KDM4C	111	Q9H3R0
YSWYDSIILKGYKRP	ABCC2	206	Q92887
KCVKYWPDEYALKEY	PTPN11	366	Q06124
YWTKYYDFKNPIIEK	OAS1	271	P00973
WRRETYPYYDLQVKV	PLA2G4F	36	Q68DD2
WKKYPLPENAENMYY	OSBP2	786	Q969R2
YVYDSYITKPEKWAN	MANEA	266	Q5SRI9
YAIWKYLYRSPTDFM	MMD	221	Q15546
TKWYDAYFNKARPYF	PTPRQ	1846	Q9UMZ3
KPYYYNSQTKESRWA	PRPF40A	196	O75400
VWMDEYKQYYYAARP	GALNT14	361	Q96FL9
YPKQYEWVLIAAYVA	HCRTR1	41	O43613
KYKVWDSYGRPLYNS	IFT80	211	Q9P2H3
EIWCRYYYPNVRDQK	C2CD3	1111	Q4AC94
RYIPKNQHQYKVWYV	CACNA1C	1221	Q13936
YYQVKQPCWYETVKV	DOCK5	501	Q9H7D0
YDTIFAKYNWPDRKV	CACNA2D3	376	Q8IZS8
CRVIGYPYYSIKWYK	DSCAML1	526	Q8TD84
YPYYSIKWYKDALLL	DSCAML1	531	Q8TD84
EKYNWPDCKVRVFTY	CACNA2D4	416	Q7Z3S7
YGYPREEIVYQWKRS	GABRG2	211	P18507
TKHYPYYRTADKGWQ	FOXK1	336	P85037
NWIGSQYKKVVYREY	HEPHL1	776	Q6MZM0
KYYILRPEVIETYWY	MAN1A2	526	O60476
NWISYDLKKRYCYLP	ENC1	216	O14682
KYDKVGIPEFYKYLW	GTF2IRD2	881	Q86UP8
KYDKVGIPEFYKYLW	GTF2IRD2B	881	Q6EKJ0
LDLISYGQDWRKYYK	HEXB	451	P07686
YGQDWRKYYKVEPLD	HEXB	456	P07686
SRPQWVAYKYNVDYK	PIWIL3	136	Q7Z3Z3
WKTTPAAHKYYYSEV	MIF4GD	206	A9UHW6
KSTYQLWKAGYYIVV	OTOGL	1031	Q3ZCN5
LWKAGYYIVVYFPEK	OTOGL	1036	Q3ZCN5
RVIGYPYYSIKWYKN	DSCAM	526	O60469
LLYLTRKYKVPDYWY	GSTT1	71	P30711
RKYKVPDYWYPQDLQ	GSTT1	76	P30711
LKPYMTYEYRISAWN	USH2A	3466	O75445
PGVYTKVYNYVDWIK	PRSS3P2	226	Q8NHM4
KVYWYKDQEPLEFSY	MMP23B	331	O75900
YETLPREIDRKWYYD	RHBDL3	141	P58872
YKWLPVYQKEVMAAY	MYH15	146	Q9Y2K3
LDYLAPYAKYKVWIK	NIP7	86	Q9Y221
QRLAPKYYWAAPEAY	LAMA1	561	P25391
KYYWAAPEAYLGNKL	LAMA1	566	P25391
YDKGLVYRSYKPVFW	IARS2	231	Q9NSE4
LITFYYYWKKTPEAA	RERE	431	Q9P2R6
DNLPEKYWRKYQYAS	PLK4	676	O00444
KYWRKYQYASRFVQL	PLK4	681	O00444
LDYEWKVVNPYYLRV	PRKAA1	431	Q13131
AVRFYPWTIDNKYYS	AAGAB	41	Q6PD74
SWTYKDDPCQKYYEL	CLCC1	271	Q96S66
EYKIVLRKSYWDSAY	SNX17	196	Q15036
GNRYDGIYKVVKYWP	UHRF2	581	Q96PU4
VQRARYEAANWKYKY	PSMA6	91	P60900
YKDEPWKYLESEEYQ	MRPS18B	51	Q9Y676
WENPSTEVDYYKLRY	TNN	371	Q9UQP3
IWVENKTPDGKVYYY	TCERG1	136	O14776
PKWEDNVYMYLYFVI	SCN10A	1386	Q9Y5Y9
VRDVYWKIYNSIYIG	SF3B1	1261	O75533
LFWPKSKCYDYLYQE	RIPPLY2	81	Q5TAB7
YIYVTYKKPDVNWGS	SLC12A2	746	P55011
VNYYSCSYWKGKVPR	TBC1D9	161	Q6ZT07
VPKIFYVTEKAWNYY	PITPNC1	76	Q9UKF7
WTYVYPAKYSDIKSE	ZNF609	1141	O15014
PGVYTKVYNYVDWIK	PRSS2	226	P07478
ETRDTTYYLFWYKQP	TRAV19	46	A0A0A6YYK7
YDYDVCRKPYKKWED	HIVEP2	636	P31629
WKNYKTYKEYIDNRR	ARHGAP21	386	Q5T5U3
RYALKNGQLKWYEDY	ZHX3	816	Q9H4I2
SPVYIWDLARYYANK	TMEM14EP	66	Q6UXP3
YWKHNIYYPVDLKNS	LRRIQ3	286	A6PVS8