Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	ATP hydrolysis activity	DNAH10 VWA8 ABCA12 ABCA13 DHX57 IDE TRIP13 ATP10A EIF4A1 MCM9 KIF28P DNAH5 DNAH6 DHX29 DNAH9 DDX39B	1.13e-06	441	169	16	GO:0016887
GeneOntologyMolecularFunction	ribonucleoside triphosphate phosphatase activity	DIRAS1 DNAH10 VWA8 ABCA12 ABCA13 LRRK2 DHX57 IDE TRIP13 ATP10A EIF4A1 MCM9 KIF28P RAB15 GNAS DNAH5 DNAH6 DHX29 DNAH9 DDX39B DIRAS2	2.60e-06	775	169	21	GO:0017111
GeneOntologyMolecularFunction	ATP-dependent activity	DNAH10 VWA8 MYO9A ABCA12 ABCA13 DHX57 IDE TRIP13 ATP10A EIF4A1 MCM9 KIF28P CCT8L1P DNAH5 DNAH6 DHX29 DNAH9 DDX39B	4.86e-06	614	169	18	GO:0140657
GeneOntologyMolecularFunction	pyrophosphatase activity	DIRAS1 DNAH10 VWA8 ABCA12 ABCA13 LRRK2 DHX57 IDE TRIP13 ATP10A EIF4A1 MCM9 KIF28P RAB15 GNAS DNAH5 DNAH6 DHX29 DNAH9 DDX39B DIRAS2	8.81e-06	839	169	21	GO:0016462
GeneOntologyMolecularFunction	hydrolase activity, acting on acid anhydrides	DIRAS1 DNAH10 VWA8 ABCA12 ABCA13 LRRK2 DHX57 IDE TRIP13 ATP10A EIF4A1 MCM9 KIF28P RAB15 GNAS DNAH5 DNAH6 DHX29 DNAH9 DDX39B DIRAS2	8.97e-06	840	169	21	GO:0016817
GeneOntologyMolecularFunction	hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides	DIRAS1 DNAH10 VWA8 ABCA12 ABCA13 LRRK2 DHX57 IDE TRIP13 ATP10A EIF4A1 MCM9 KIF28P RAB15 GNAS DNAH5 DNAH6 DHX29 DNAH9 DDX39B DIRAS2	8.97e-06	840	169	21	GO:0016818
GeneOntologyMolecularFunction	minus-end-directed microtubule motor activity	DNAH10 DNAH5 DNAH6 DNAH9	1.38e-05	18	169	4	GO:0008569
GeneOntologyMolecularFunction	dynein intermediate chain binding	DNAH10 BICD1 DNAH5 DNAH6 DNAH9	1.43e-05	37	169	5	GO:0045505
GeneOntologyMolecularFunction	GTPase activator activity	ARHGAP42 MYO9A LRRK2 ARHGEF12 TBC1D22B SIPA1 DOCK5 RASA4 RASA4B RAPGEF2 MTSS2	2.67e-05	279	169	11	GO:0005096
GeneOntologyMolecularFunction	dynein light intermediate chain binding	DNAH10 DNAH5 DNAH6 DNAH9	8.65e-05	28	169	4	GO:0051959
GeneOntologyMolecularFunction	cytoskeletal protein binding	ABL2 MAP2 MYO9A SYNE1 CEP295NL LRRK2 BICD1 ARPC2 PROM1 DES DST CEP44 CLTC DIAPH2 KIF28P GNAS CAPZA3 DMD MTUS2 FRMD5 MTSS2 NIN	1.53e-04	1099	169	22	GO:0008092
GeneOntologyMolecularFunction	transketolase activity	TKTL1 TKT	2.12e-04	3	169	2	GO:0004802
GeneOntologyMolecularFunction	microtubule motor activity	DNAH10 KIF28P DNAH5 DNAH6 DNAH9	3.18e-04	70	169	5	GO:0003777
GeneOntologyMolecularFunction	nucleoside-triphosphatase regulator activity	ARHGAP42 MYO9A RGL3 LRRK2 ARHGEF12 TBC1D22B SIPA1 DOCK5 RASA4 IQSEC1 RASA4B RAPGEF2 MTSS2	3.93e-04	507	169	13	GO:0060589
GeneOntologyMolecularFunction	GTPase regulator activity	ARHGAP42 MYO9A RGL3 LRRK2 ARHGEF12 TBC1D22B SIPA1 DOCK5 RASA4 IQSEC1 RASA4B RAPGEF2 MTSS2	3.93e-04	507	169	13	GO:0030695
GeneOntologyMolecularFunction	small GTPase binding	EXPH5 RGL3 LRRK2 BICD1 DOCK5 RPTOR HPS6 DIAPH2 IPO13 MTSS2	4.21e-04	321	169	10	GO:0031267
GeneOntologyMolecularFunction	anandamide 8,9 epoxidase activity	CYP2D7 CYP2D6	4.23e-04	4	169	2	GO:0062187
GeneOntologyMolecularFunction	anandamide 11,12 epoxidase activity	CYP2D7 CYP2D6	4.23e-04	4	169	2	GO:0062188
GeneOntologyMolecularFunction	steroid 21-monooxygenase activity	CYP2D7 CYP2D6	4.23e-04	4	169	2	GO:0004509
GeneOntologyMolecularFunction	progesterone 21-hydroxylase activity	CYP2D7 CYP2D6	4.23e-04	4	169	2	GO:0106309
GeneOntologyMolecularFunction	enzyme activator activity	ARHGAP42 MYO9A LRRK2 ARHGEF12 CASP8 TBC1D22B SIPA1 DOCK5 MALT1 RASA4 RPTOR RASA4B GNAS RAPGEF2 MTSS2	4.74e-04	656	169	15	GO:0008047
GeneOntologyMolecularFunction	cytoskeletal motor activity	DNAH10 MYO9A KIF28P DNAH5 DNAH6 DNAH9	5.07e-04	118	169	6	GO:0003774
GeneOntologyMolecularFunction	transketolase or transaldolase activity	TKTL1 TKT	7.00e-04	5	169	2	GO:0016744
GeneOntologyMolecularFunction	GTPase binding	EXPH5 RGL3 LRRK2 BICD1 DOCK5 RPTOR HPS6 DIAPH2 IPO13 MTSS2	1.02e-03	360	169	10	GO:0051020
GeneOntologyMolecularFunction	anandamide 14,15 epoxidase activity	CYP2D7 CYP2D6	1.04e-03	6	169	2	GO:0062189
GeneOntologyMolecularFunction	anandamide epoxidase activity	CYP2D7 CYP2D6	1.04e-03	6	169	2	GO:0062186
GeneOntologyMolecularFunction	thiamine pyrophosphate binding	TKTL1 TKT	1.93e-03	8	169	2	GO:0030976
GeneOntologyCellularComponent	cilium	CYLD TCTE1 PDE6A DNAH10 CEP295NL ADCY3 PIK3R4 PROM1 TTC21B ULK4 RAB15 MERTK CATSPERG DNAH5 DNAH6 DNAH9 CNGB1 PMFBP1 DRC3 NIN	4.03e-05	898	169	20	GO:0005929
GeneOntologyCellularComponent	axonemal dynein complex	DNAH10 DNAH5 DNAH6 DNAH9	4.57e-05	25	169	4	GO:0005858
GeneOntologyCellularComponent	postsynapse	TNIK ABL2 MAP2 MYO9A SYNE1 LRRK2 ZZEF1 RTN1 ITPR1 ARPC2 DLGAP3 DST UBE3A ELFN1 CLTC IQSEC1 SLITRK5 DMD CTNND2 RAPGEF2 GABRA2	7.69e-05	1018	169	21	GO:0098794
GeneOntologyCellularComponent	supramolecular fiber	CYLD DNAH10 MAP2 MYO9A SYNE1 CMYA5 BICD1 ARPC2 DES DST UNC45B CLTC DIAPH2 KIF28P PYGM DMD ZW10 DNAH5 DNAH6 DNAH9 MTUS2 NIN	2.17e-04	1179	169	22	GO:0099512
GeneOntologyCellularComponent	supramolecular polymer	CYLD DNAH10 MAP2 MYO9A SYNE1 CMYA5 BICD1 ARPC2 DES DST UNC45B CLTC DIAPH2 KIF28P PYGM DMD ZW10 DNAH5 DNAH6 DNAH9 MTUS2 NIN	2.39e-04	1187	169	22	GO:0099081
GeneOntologyCellularComponent	polymeric cytoskeletal fiber	CYLD DNAH10 MAP2 MYO9A BICD1 ARPC2 DES DST CLTC DIAPH2 KIF28P DMD ZW10 DNAH5 DNAH6 DNAH9 MTUS2 NIN	3.68e-04	899	169	18	GO:0099513
GeneOntologyCellularComponent	microtubule	CYLD DNAH10 MAP2 BICD1 DST CLTC KIF28P ZW10 DNAH5 DNAH6 DNAH9 MTUS2 NIN	4.10e-04	533	169	13	GO:0005874
GeneOntologyCellularComponent	endosome	TNIK EXPH5 VPS13C UBR4 LRRK2 APOB TLR7 IDE ARPC2 PIK3R4 VIPAS39 SNX32 HPS6 CLTC SNX10 DIAPH2 RAB15 GNAS RAPGEF2 VPS13B FCHSD1	4.92e-04	1167	169	21	GO:0005768
GeneOntologyCellularComponent	cytoplasmic region	DNAH10 MAP2 LRRK2 PPFIA3 PIK3R4 DST DNAH5 DNAH6 DNAH9 DRC3	7.20e-04	360	169	10	GO:0099568
GeneOntologyCellularComponent	9+2 motile cilium	TCTE1 DNAH10 CATSPERG DNAH5 DNAH6 DNAH9 PMFBP1 DRC3	7.28e-04	238	169	8	GO:0097729
GeneOntologyCellularComponent	postsynaptic specialization	TNIK MAP2 RTN1 ITPR1 DLGAP3 DST ELFN1 IQSEC1 SLITRK5 DMD CTNND2 GABRA2	8.29e-04	503	169	12	GO:0099572
GeneOntologyCellularComponent	sarcolemma	CACNB3 DES DST CCDC78 CLTC GNAS DMD	9.17e-04	190	169	7	GO:0042383
GeneOntologyCellularComponent	dynein complex	DNAH10 DNAH5 DNAH6 DNAH9	9.52e-04	54	169	4	GO:0030286
GeneOntologyCellularComponent	type III intermediate filament	DES DST	9.54e-04	6	169	2	GO:0045098
GeneOntologyCellularComponent	plasma membrane bounded cell projection cytoplasm	DNAH10 MAP2 LRRK2 PIK3R4 DST DNAH5 DNAH6 DNAH9 DRC3	1.14e-03	317	169	9	GO:0032838
GeneOntologyCellularComponent	postsynaptic density	TNIK MAP2 RTN1 ITPR1 DLGAP3 DST ELFN1 IQSEC1 SLITRK5 DMD CTNND2	1.14e-03	451	169	11	GO:0014069
Domain	ARM-type_fold	TRPC4AP INTS7 UBR4 LRRK2 APOB FRYL ITPR1 PIK3R4 DOCK5 UNC45B RPTOR CLTC DIAPH2 IPO13 ULK4 PRKDC CTNND2	8.85e-09	339	165	17	IPR016024
Domain	ATPase_dyneun-rel_AAA	DNAH10 VWA8 DNAH5 DNAH6 DNAH9	9.51e-08	14	165	5	IPR011704
Domain	AAA_5	DNAH10 VWA8 DNAH5 DNAH6 DNAH9	9.51e-08	14	165	5	PF07728
Domain	SHR-BD	VPS13C VPS13D VPS13B	2.69e-06	4	165	3	IPR009543
Domain	VPS13_C	VPS13C VPS13D VPS13B	2.69e-06	4	165	3	PF16909
Domain	VPS13_C	VPS13C VPS13D VPS13B	2.69e-06	4	165	3	IPR031645
Domain	SHR-BD	VPS13C VPS13D VPS13B	2.69e-06	4	165	3	PF06650
Domain	-	CACNB3 DIRAS1 DNAH10 VWA8 ABCA12 ABCA13 LRRK2 DHX57 TRIP13 URGCP CHST15 EIF4A1 MCM9 RAB15 GNAS DNAH5 DNAH6 DHX29 DNAH9 DDX39B DIRAS2	2.73e-06	746	165	21	3.40.50.300
Domain	AAA	DNAH10 VWA8 ABCA12 ABCA13 TRIP13 MCM9 DNAH5 DNAH6 DNAH9	5.41e-06	144	165	9	SM00382
Domain	AAA+_ATPase	DNAH10 VWA8 ABCA12 ABCA13 TRIP13 MCM9 DNAH5 DNAH6 DNAH9	5.41e-06	144	165	9	IPR003593
Domain	Dynein_heavy_chain_D4_dom	DNAH10 DNAH5 DNAH6 DNAH9	5.49e-06	14	165	4	IPR024317
Domain	Dynein_HC_stalk	DNAH10 DNAH5 DNAH6 DNAH9	5.49e-06	14	165	4	IPR024743
Domain	Dynein_heavy_dom-2	DNAH10 DNAH5 DNAH6 DNAH9	5.49e-06	14	165	4	IPR013602
Domain	DHC_N2	DNAH10 DNAH5 DNAH6 DNAH9	5.49e-06	14	165	4	PF08393
Domain	MT	DNAH10 DNAH5 DNAH6 DNAH9	5.49e-06	14	165	4	PF12777
Domain	AAA_8	DNAH10 DNAH5 DNAH6 DNAH9	5.49e-06	14	165	4	PF12780
Domain	P-loop_NTPase	CACNB3 DIRAS1 DNAH10 VWA8 MYO9A ABCA12 ABCA13 LRRK2 DHX57 TRIP13 URGCP CHST15 EIF4A1 MCM9 RAB15 GNAS DNAH5 DNAH6 DHX29 DNAH9 DDX39B DIRAS2	5.78e-06	848	165	22	IPR027417
Domain	DHC_fam	DNAH10 DNAH5 DNAH6 DNAH9	7.43e-06	15	165	4	IPR026983
Domain	Dynein_heavy	DNAH10 DNAH5 DNAH6 DNAH9	7.43e-06	15	165	4	PF03028
Domain	Dynein_heavy_dom	DNAH10 DNAH5 DNAH6 DNAH9	7.43e-06	15	165	4	IPR004273
Domain	-	INTS7 LRRK2 FRYL PIK3R4 UNC45B RPTOR IPO13 ULK4 PRKDC CTNND2	2.89e-05	222	165	10	1.25.10.10
Domain	Chorein_N	VPS13C VPS13D VPS13B	3.67e-05	8	165	3	PF12624
Domain	DHC_N1	DNAH10 DNAH5 DNAH9	3.67e-05	8	165	3	PF08385
Domain	VPS13_N	VPS13C VPS13D VPS13B	3.67e-05	8	165	3	IPR026854
Domain	Dynein_heavy_dom-1	DNAH10 DNAH5 DNAH9	3.67e-05	8	165	3	IPR013594
Domain	Transketolase_BS	TKTL1 TKT	7.76e-05	2	165	2	IPR020826
Domain	ARM-like	INTS7 LRRK2 FRYL PIK3R4 UNC45B RPTOR IPO13 ULK4 PRKDC CTNND2	1.48e-04	270	165	10	IPR011989
Domain	Transketolase_N	TKTL1 TKT	2.31e-04	3	165	2	PF00456
Domain	Transketolase_N	TKTL1 TKT	2.31e-04	3	165	2	IPR005474
Domain	VPS13	VPS13C VPS13D	2.31e-04	3	165	2	IPR026847
Domain	VPS13_mid_rpt	VPS13C VPS13D	2.31e-04	3	165	2	PF16910
Domain	VPS13	VPS13C VPS13D	2.31e-04	3	165	2	PF16908
Domain	TRANSKETOLASE_1	TKTL1 TKT	2.31e-04	3	165	2	PS00801
Domain	TRANSKETOLASE_2	TKTL1 TKT	2.31e-04	3	165	2	PS00802
Domain	-	RASA4 RASA4B	2.31e-04	3	165	2	4.10.1130.10
Domain	VPS13_N2	VPS13C VPS13D	2.31e-04	3	165	2	IPR031646
Domain	VPS13_mid_rpt	VPS13C VPS13D	2.31e-04	3	165	2	IPR031642
Domain	-	LRRC74A ZZEF1 STAT4 PPP2R3A DST NECAB1 DMD PLCH1 NIN	5.33e-04	261	165	9	1.10.238.10
Domain	TPR_REGION	SH3TC2 DNAH10 TTC6 UNC45B TTC21B TTC13 PRKDC	6.68e-04	165	165	7	PS50293
Domain	TPR	SH3TC2 DNAH10 TTC6 UNC45B TTC21B TTC13 PRKDC	6.68e-04	165	165	7	PS50005
Domain	Transketolase_C	TKTL1 TKT	7.62e-04	5	165	2	IPR033248
Domain	Transketolase_fam	TKTL1 TKT	7.62e-04	5	165	2	IPR033247
Domain	Autophagy-rel_C	VPS13C VPS13B	7.62e-04	5	165	2	IPR015412
Domain	ATG_C	VPS13C VPS13B	7.62e-04	5	165	2	PF09333
Domain	Transketo_C/PFOR_II	TKTL1 TKT	7.62e-04	5	165	2	IPR009014
Domain	Transketolase_C	TKTL1 TKT	7.62e-04	5	165	2	PF02780
Domain	-	TKTL1 TKT	7.62e-04	5	165	2	3.40.50.920
Domain	EF-hand-dom_pair	LRRC74A ZZEF1 STAT4 PPP2R3A DST NECAB1 DMD PLCH1 NIN	1.05e-03	287	165	9	IPR011992
Domain	Spectrin	SYNE1 DST DMD	1.05e-03	23	165	3	PF00435
Domain	ACTININ_2	SYNE1 DST DMD	1.05e-03	23	165	3	PS00020
Domain	ACTININ_1	SYNE1 DST DMD	1.05e-03	23	165	3	PS00019
Domain	Actinin_actin-bd_CS	SYNE1 DST DMD	1.05e-03	23	165	3	IPR001589
Domain	Rho_GTPase_activation_prot	ARHGAP42 MYO9A RASA4 RASA4B PLXNA2	1.10e-03	88	165	5	IPR008936
Domain	TPR-like_helical_dom	SH3TC2 USP28 TTC6 UNC45B CLTC TTC21B TTC13 PRKDC	1.11e-03	233	165	8	IPR011990
Domain	PAP_assoc	TENT4B TUT7	1.58e-03	7	165	2	PF03828
Domain	PAP_assoc	TENT4B TUT7	1.58e-03	7	165	2	IPR002058
Domain	HEAT	PIK3R4 RPTOR IPO13 PRKDC	1.72e-03	58	165	4	IPR000357
Domain	Spectrin_repeat	SYNE1 DST DMD	2.09e-03	29	165	3	IPR002017
Domain	Transketolase-like_Pyr-bd	TKTL1 TKT	2.10e-03	8	165	2	IPR005475
Domain	Transket_pyr	TKTL1 TKT	2.10e-03	8	165	2	SM00861
Domain	Transket_pyr	TKTL1 TKT	2.10e-03	8	165	2	PF02779
Domain	TPR-contain_dom	SH3TC2 TTC6 UNC45B TTC21B TTC13 PRKDC	2.18e-03	150	165	6	IPR013026
Domain	UBA-like	USP28 DHX57 VPS13D ASCC2	2.47e-03	64	165	4	IPR009060
Domain	RA	MYO9A RGL3 RAPGEF2	2.54e-03	31	165	3	SM00314
Domain	BTK	RASA4 RASA4B	2.68e-03	9	165	2	SM00107
Domain	Znf_Btk_motif	RASA4 RASA4B	2.68e-03	9	165	2	IPR001562
Domain	BTK	RASA4 RASA4B	2.68e-03	9	165	2	PF00779
Domain	ZF_BTK	RASA4 RASA4B	2.68e-03	9	165	2	PS51113
Domain	SPEC	SYNE1 DST DMD	2.78e-03	32	165	3	SM00150
Domain	Spectrin/alpha-actinin	SYNE1 DST DMD	2.78e-03	32	165	3	IPR018159
Domain	SH3	ARHGAP42 SH3TC2 CACNB3 ABL2 DOCK5 DST FCHSD1	3.13e-03	216	165	7	PS50002
Domain	SH3_1	ARHGAP42 SH3TC2 ABL2 DOCK5 DST FCHSD1	3.40e-03	164	165	6	PF00018
Domain	HEAT_REPEAT	PIK3R4 IPO13 ULK4 PRKDC	3.42e-03	70	165	4	PS50077
Domain	SH3_domain	ARHGAP42 SH3TC2 CACNB3 ABL2 DOCK5 DST FCHSD1	3.46e-03	220	165	7	IPR001452
Domain	RA	MYO9A RGL3 RAPGEF2	3.90e-03	36	165	3	PF00788
Domain	DEAD/DEAH_box_helicase_dom	DHX57 EIF4A1 DHX29 DDX39B	3.98e-03	73	165	4	IPR011545
Domain	DEAD	DHX57 EIF4A1 DHX29 DDX39B	3.98e-03	73	165	4	PF00270
Domain	NTP_transf_2	TENT4B TUT7	4.05e-03	11	165	2	PF01909
Domain	Polymerase_NTP_transf_dom	TENT4B TUT7	4.05e-03	11	165	2	IPR002934
Domain	RA	MYO9A RGL3 RAPGEF2	4.22e-03	37	165	3	PS50200
Domain	ABC_A	ABCA12 ABCA13	4.83e-03	12	165	2	IPR026082
Domain	RA_dom	MYO9A RGL3 RAPGEF2	5.26e-03	40	165	3	IPR000159
Domain	I-BAR_dom	ARHGAP42 MTSS2	5.68e-03	13	165	2	IPR013606
Domain	THDP-binding	TKTL1 TKT	5.68e-03	13	165	2	IPR029061
Domain	-	TKTL1 TKT	5.68e-03	13	165	2	3.40.50.970
Domain	TPR	SH3TC2 TTC6 UNC45B TTC21B TTC13	5.79e-03	129	165	5	SM00028
Domain	RasGAP	RASA4 RASA4B	6.58e-03	14	165	2	SM00323
Domain	-	CASP8 MALT1	6.58e-03	14	165	2	3.40.50.1460
Domain	Pept_C14_p20	CASP8 MALT1	6.58e-03	14	165	2	IPR001309
Domain	Caspase-like_dom	CASP8 MALT1	6.58e-03	14	165	2	IPR029030
Domain	CASPASE_P20	CASP8 MALT1	6.58e-03	14	165	2	PS50208
Domain	RasGAP_CS	RASA4 RASA4B	6.58e-03	14	165	2	IPR023152
Domain	RasGAP	RASA4 RASA4B	7.55e-03	15	165	2	PF00616
Domain	RAS_GTPASE_ACTIV_1	RASA4 RASA4B	7.55e-03	15	165	2	PS00509
Domain	RAS_GTPASE_ACTIV_2	RASA4 RASA4B	7.55e-03	15	165	2	PS50018
Domain	TPR_1	SH3TC2 TTC6 UNC45B TTC13	8.33e-03	90	165	4	IPR001440
Domain	TPR_1	SH3TC2 TTC6 UNC45B TTC13	8.33e-03	90	165	4	PF00515
Domain	-	RASA4 RASA4B	8.58e-03	16	165	2	1.10.506.10
Domain	HEAT	PIK3R4 RPTOR PRKDC	8.75e-03	48	165	3	PF02985
Pubmed	Defining the proximal interaction networks of Arf GTPases reveals a mechanism for the regulation of PLD1 and PI4KB.	CYLD HK1 TENT4B VPS13C GOSR1 LRRK2 TBC1D22B APOB USP19 DOCK5 WDR3 PPP2R3A VIPAS39 LIPE DST CLTC SLITRK5 PRKDC RAPGEF2 DEPDC7 CUX1	3.75e-10	777	173	21	35844135
Pubmed	Spatiotemporal profile of postsynaptic interactomes integrates components of complex brain disorders.	TNIK CYLD USP28 SYNE1 UBR4 HECTD4 ARHGEF12 PPFIA3 SIPA1 RTN1 ARPC2 DLGAP3 DST UBE3A RPTOR EIF4A1 CLTC DIAPH2 IQSEC1 CTNND2 RAPGEF2 CUX1 MTSS2	5.64e-10	963	173	23	28671696
Pubmed	Gain of Additional BIRC3 Protein Functions through 3'-UTR-Mediated Protein Complex Formation.	HK1 TENT4B RARS1 DNAH10 VPS13C SYNE1 UBR4 APOB IDE DBT CMYA5 TRIP13 USP19 NUP205 ARPC2 PIK3R4 WDR3 TKT RPTOR EIF4A1 CLTC PRKDC TAF5L GNAS DNAH5 DHX29 DDX39B	2.46e-09	1425	173	27	30948266
Pubmed	Neuron-specific protein network mapping of autism risk genes identifies shared biological mechanisms and disease-relevant pathologies.	TNIK CYLD RARS1 DIRAS1 MAP2 VWA8 UBR4 PPFIA3 DBT RTN1 ITPR1 DLGAP3 VIPAS39 UBE3A ELFN1 RPTOR CLTC IQSEC1 SLITRK5 CTNND2 DHX29 DDX39B DIRAS2 GABRA2	2.73e-09	1139	173	24	36417873
Pubmed	A High-Density Human Mitochondrial Proximity Interaction Network.	HK1 VWA8 VPS13C SYNE1 TUT7 UBR4 FASTKD1 DHX57 IDE DBT ZZEF1 RTN1 USP19 ITPR1 WDR3 VPS13D VIPAS39 DST RPTOR CLTC TTC13 MTFR2 GNAS ZW10 DDX39B VPS13B CUX1	6.89e-09	1496	173	27	32877691
Pubmed	KCTD13-mediated ubiquitination and degradation of GluN1 regulates excitatory synaptic transmission and seizure susceptibility.	HK1 MAP2 MYO9A SYNE1 ARHGEF12 DHX57 PPFIA3 SIPA1 RTN1 ARPC2 PIK3R4 DLGAP3 DST TKT RPTOR CLTC IQSEC1 DMD CTNND2 RAPGEF2 PLCH1 DNAH6 DHX29 DDX39B MTUS2 DIRAS2	1.18e-08	1431	173	26	37142655
Pubmed	Kelch Domain of Gigaxonin Interacts with Intermediate Filament Proteins Affected in Giant Axonal Neuropathy.	DNAH10 SYNE1 ARHGEF12 ZZEF1 DST EIF4A1 ANKRD36 DMD DNAH6 CUX1	3.78e-08	187	173	10	26460568
Pubmed	Prediction of the coding sequences of unidentified human genes. IX. The complete sequences of 100 new cDNA clones from brain which can code for large proteins in vitro.	TNIK VWA8 ERAP1 ATP10A ADCY3 CHST15 RASA4 VPS13B	5.89e-08	105	173	8	9628581
Pubmed	Proteomic profiling of VCP substrates links VCP to K6-linked ubiquitylation and c-Myc function.	PHLDB3 HK1 RARS1 MYO9A TUT7 UBR4 CASP8 DHX57 TRIP13 NUP205 PIK3R4 WDR3 GSTZ1 DST TFB1M UBE3A TKT RPTOR EIF4A1 CLTC IQSEC1 PRKDC DHX29 DDX39B	7.17e-08	1353	173	24	29467282
Pubmed	Voltage-dependent conformational changes of Kv1.3 channels activate cell proliferation.	RARS1 MYO9A ABCA13 EXPH5 LAMA1 LRRK2 CEP112 RPTOR EIF4A1 DNAH5	1.03e-07	208	173	10	33230847
Pubmed	Chr21 protein-protein interactions: enrichment in proteins involved in intellectual disability, autism, and late-onset Alzheimer's disease.	CYLD KDM3A USP28 SYNE1 UBR4 HECTD4 CMYA5 BICD1 PIK3R4 WDR3 DST NECAB1 UBE3A EIF4A1 ZNF197 CLTC ANKRD36 PRKDC CTNND2 MERTK RAPGEF2 MTUS2 CUX1	1.18e-07	1285	173	23	35914814
Pubmed	In-Depth In Vivo Crosslinking in Minutes by a Compact, Membrane-Permeable, and Alkynyl-Enrichable Crosslinker.	PDE6A HK1 SYNE1 UBR4 DHX57 APOB TKTL1 TRIP13 NUP205 ARPC2 DES DST CEP112 TKT FAM186A EIF4A1 CLTC PRKDC DMD PLCH1 DNAH6 DDX39B PLXNA2 CUX1	2.30e-07	1442	173	24	35575683
Pubmed	C5orf51 is a component of the MON1-CCZ1 complex and controls RAB7A localization and stability during mitophagy.	VPS13C GOSR1 DHX57 RTN1 BICD1 ITPR1 PIK3R4 VPS13D VIPAS39 DST RPTOR DIAPH2 ZW10 VPS13B	2.65e-07	504	173	14	34432599
Pubmed	Ex vivo Quantitative Proteomic Analysis of Serotonin Transporter Interactome: Network Impact of the SERT Ala56 Coding Variant.	TNIK MYO9A VPS13C PPFIA3 ARPC2 DLGAP3 TFB1M ELFN1 RPTOR IQSEC1 RAPGEF2 DIRAS2 MTSS2	2.77e-07	430	173	13	32581705
Pubmed	Prominin 1 and Notch regulate ciliary length and dynamics in multiciliated cells of the airway epithelium.	PROM1 DNAH5 DNAH6 DNAH9	4.08e-07	13	173	4	35942101
Pubmed	Identification, tissue specific expression, and chromosomal localisation of several human dynein heavy chain genes.	DNAH10 DNAH6 DNAH9	4.82e-07	4	173	3	11175280
Pubmed	Analysis of the human VPS13 gene family.	VPS13C VPS13D VPS13B	4.82e-07	4	173	3	15498460
Pubmed	A human MAP kinase interactome.	ABL2 MYO9A EXPH5 SYNE1 PROM1 DES DST CLTC DIAPH2 PRKDC DMD RAPGEF2 CUX1	1.09e-06	486	173	13	20936779
Pubmed	Genome-wide CRISPR screen identifies HNRNPL as a prostate cancer dependency regulating RNA splicing.	CACNB3 TRPC4AP MAP2 MYO9A VPS13C HECTD4 FRYL IDE SLC10A7 TRIP13 ATP10A ADCY3 BICD1 DOCK5 MALT1 PPP2R3A RPTOR TTC21B GNAS RAPGEF2 CATSPERG VPS13B CUX1	1.50e-06	1489	173	23	28611215
Pubmed	A central chaperone-like role for 14-3-3 proteins in human cells.	CYLD ABL2 MAP2 MYO9A EXPH5 TBC1D22B FRYL PIK3R4 VPS13D DST CEP112 RPTOR IQSEC1 GNAS RAPGEF2 PLCH1 MTSS2	1.60e-06	861	173	17	36931259
Pubmed	Synaptic GAP and GEF Complexes Cluster Proteins Essential for GTP Signaling.	TNIK CACNB3 ABL2 SYNE1 DLGAP3 CLTC IQSEC1 GNAS CTNND2 RAPGEF2	1.61e-06	281	173	10	28706196
Pubmed	Estrogen-regulated feedback loop limits the efficacy of estrogen receptor-targeted breast cancer therapy.	CYLD TRPC4AP LRRK2 ARHGEF12 IDE CMYA5 ZNF776 SNX10 NCOA1 TTC13 C5 DHX29 CNGB1 VPS13B GABRA2	1.97e-06	686	173	15	29987050
Pubmed	Prediction of the coding sequences of mouse homologues of KIAA gene: III. the complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.	KDM3A VWA8 USP28 VPS13C HECTD4 ZZEF1 URGCP NUP205 DST RPTOR IPO13 HMGXB3 NIN	2.78e-06	529	173	13	14621295
Pubmed	USP7 targets XIAP for cancer progression: Establishment of a p53-independent therapeutic avenue for glioma.	SYNE1 LAMA1 DST FAM186A CLTC DMD PLCH1 DNAH5 VPS13B	2.88e-06	234	173	9	36243803
Pubmed	A protein-interaction network of interferon-stimulated genes extends the innate immune system landscape.	HK1 VWA8 COG7 GOSR1 UBR4 DHX57 TRIP13 ITPR1 NUP205 ARPC2 WDR3 DST CEP44 EIF4A1 CLTC ASCC2 IPO13 PRKDC GNAS ZW10 DHX29 CUX1	3.10e-06	1440	173	22	30833792
Pubmed	Hepatitis B Virus HBx Protein Mediates the Degradation of Host Restriction Factors through the Cullin 4 DDB1 E3 Ubiquitin Ligase Complex.	PDE6A HK1 ERAP1 UBR4 PBLD IDE DES UBE3A DMD DDX39B	3.25e-06	304	173	10	32235678
Pubmed	Protein interactome mining defines melatonin MT1 receptors as integral component of presynaptic protein complexes of neurons.	MAP2 MYO9A USP28 UBR4 ADCY3 LIPE DST PRKDC GNAS DMD	5.40e-06	322	173	10	26514267
Pubmed	A disintegrin and metalloproteinase with thrombospondin motifs 2 cleaves and inactivates Reelin in the postnatal cerebral cortex and hippocampus, but not in the cerebellum.	MAP2 ITPR1 CUX1	9.94e-06	9	173	3	31491533
Pubmed	Disrupted in Schizophrenia 1 Interactome: evidence for the close connectivity of risk genes and a potential synaptic basis for schizophrenia.	TNIK SYNE1 FRYL BICD1 DST ZNF197 DMD	1.13e-05	151	173	7	17043677
Pubmed	Prediction of the coding sequences of unidentified human genes. XI. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro.	KDM3A SYNE1 DST IQSEC1 IPO13 MTUS2	1.19e-05	101	173	6	9872452
Pubmed	The deubiquitinase TRABID stabilizes the K29/K48-specific E3 ubiquitin ligase HECTD1.	RARS1 UBR4 ZZEF1 URGCP PIK3R4 DST TFB1M UBE3A	1.19e-05	212	173	8	33853758
Pubmed	La-related Protein 1 (LARP1) Represses Terminal Oligopyrimidine (TOP) mRNA Translation Downstream of mTOR Complex 1 (mTORC1).	RARS1 TKT RPTOR EIF4A1 HPS6 DDX39B	1.94e-05	110	173	6	25940091
Pubmed	LMBR1L regulates lymphopoiesis through Wnt/β-catenin signaling.	RARS1 INTS7 TUT7 UBR4 TRIP13 RTN1 URGCP USP19 NUP205 UBE3A RPTOR EIF4A1 CLTC TTC13 PRKDC ZW10	2.12e-05	942	173	16	31073040
Pubmed	Widespread Expansion of Protein Interaction Capabilities by Alternative Splicing.	COG7 ZBTB26 TRIP13 DES VIPAS39 TKT CEP44 MCM9 A4GALT GNAS DMD DDX39B MTUS2 GABRA2	2.28e-05	742	173	14	26871637
Pubmed	Role of thiamine status and genetic variability in transketolase and other pentose phosphate cycle enzymes in the progression of diabetic nephropathy.	TKTL1 TKT	2.46e-05	2	173	2	20826743
Pubmed	T and B lymphocyte depletion has a marked effect on the fibrosis of dystrophic skeletal muscles in the scid/mdx mouse.	PRKDC DMD	2.46e-05	2	173	2	17668421
Pubmed	The bacterium, nontypeable Haemophilus influenzae, enhances host antiviral response by inducing Toll-like receptor 7 expression: evidence for negative regulation of host anti-viral response by CYLD.	CYLD TLR7	2.46e-05	2	173	2	17608805
Pubmed	Disruption of both nesprin 1 and desmin results in nuclear anchorage defects and fibrosis in skeletal muscle.	SYNE1 DES	2.46e-05	2	173	2	24943590
Pubmed	Divergent iron regulatory states contribute to heterogeneity in breast cancer aggressiveness.	PRKDC C5	2.46e-05	2	173	2	39262774
Pubmed	Association study of the 15q11-q13 maternal expression domain in Japanese autistic patients.	ATP10A UBE3A	2.46e-05	2	173	2	18186074
Pubmed	CAPRI regulates Ca(2+)-dependent inactivation of the Ras-MAPK pathway.	RASA4 RASA4B	2.46e-05	2	173	2	11448776
Pubmed	Molecular evolution of the CYP2D subfamily in primates: purifying selection on substrate recognition sites without the frequent or long-tract gene conversion.	CYP2D7 CYP2D6	2.46e-05	2	173	2	25808902
Pubmed	Polymorphisms in CYP2D6 duplication-negative individuals with the ultrarapid metabolizer phenotype: a role for the CYP2D6*35 allele in ultrarapid metabolism?	CYP2D7 CYP2D6	2.46e-05	2	173	2	11207030
Pubmed	Role of UBE3A and ATP10A genes in autism susceptibility region 15q11-q13 in an Italian population: a positive replication for UBE3A.	ATP10A UBE3A	2.46e-05	2	173	2	20609483
Pubmed	Identification of predicted human outer dynein arm genes: candidates for primary ciliary dyskinesia genes.	DNAH10 DNAH6	2.46e-05	2	173	2	15937072
Pubmed	Age-dependent changes in diastolic Ca(2+) and Na(+) concentrations in dystrophic cardiomyopathy: Role of Ca(2+) entry and IP3.	ITPR1 DMD	2.46e-05	2	173	2	25242522
Pubmed	Incompatibility in cell adhesion constitutes a barrier to interspecies chimerism.	PRKDC C5	2.46e-05	2	173	2	39181131
Pubmed	Isolation of slow-cycling cancer cells from lung patient-derived xenograft using carboxyfluorescein-succinimidyl ester retention-mediated cell sorting.	PRKDC C5	2.46e-05	2	173	2	36924504
Pubmed	Human muscle-derived cell populations isolated by differential adhesion rates: phenotype and contribution to skeletal muscle regeneration in Mdx/SCID mice.	PRKDC DMD	2.46e-05	2	173	2	21854253
Pubmed	Targeting ferritinophagy impairs quiescent cancer stem cells in acute myeloid leukemia in vitro and in vivo models.	PRKDC C5	2.46e-05	2	173	2	39047119
Pubmed	STAT4 isoforms differentially regulate Th1 cytokine production and the severity of inflammatory bowel disease.	STAT4 PRKDC	2.46e-05	2	173	2	18802110
Pubmed	Characterization of the common genetic defect in humans deficient in debrisoquine metabolism.	CYP2D7 CYP2D6	2.46e-05	2	173	2	3123997
Pubmed	Fetal muscle-derived cells can repair dystrophic muscles in mdx mice.	DES DMD	2.46e-05	2	173	2	17275812
Pubmed	Overexpression of Protein Phosphatase 2 Regulatory Subunit B"Alpha Promotes Glycolysis by Regulating Hexokinase 1 in Hepatocellular Carcinoma.	HK1 PPP2R3A	2.46e-05	2	173	2	35945177
Pubmed	Transplantation-based screen identifies inducers of muscle progenitor cell engraftment across vertebrate species.	PRKDC DMD	2.46e-05	2	173	2	37018075
Pubmed	Temporal response of desmin and dystrophin proteins to progressive resistance exercise in human skeletal muscle.	DES DMD	2.46e-05	2	173	2	16439510
Pubmed	Cancer Cells Employ Nuclear Caspase-8 to Overcome the p53-Dependent G2/M Checkpoint through Cleavage of USP28.	USP28 CASP8	2.46e-05	2	173	2	31982308
Pubmed	Transgenic expression of Laminin α1 chain does not prevent muscle disease in the mdx mouse model for Duchenne muscular dystrophy.	LAMA1 DMD	2.46e-05	2	173	2	21435454
Pubmed	Characterization of Cyp2d22, a novel cytochrome P450 expressed in mouse mammary cells.	CYP2D7 CYP2D6	2.46e-05	2	173	2	11032406
Pubmed	Role of SPA-1 in phenotypes of chronic myelogenous leukemia induced by BCR-ABL-expressing hematopoietic progenitors in a mouse model.	SIPA1 PRKDC	2.46e-05	2	173	2	17047059
Pubmed	Caffeine Supplementation and FOXM1 Inhibition Enhance the Antitumor Effect of Statins in Neuroblastoma.	PRKDC C5	2.46e-05	2	173	2	37057874
Pubmed	MALT1 Protease Activation Triggers Acute Disruption of Endothelial Barrier Integrity via CYLD Cleavage.	CYLD MALT1	2.46e-05	2	173	2	27681433
Pubmed	Proper perinuclear localization of the TRIM-like protein myospryn requires its binding partner desmin.	CMYA5 DES	2.46e-05	2	173	2	17872945
Pubmed	MALT1-dependent cleavage of CYLD promotes NF-κB signaling and growth of aggressive B-cell receptor-dependent lymphomas.	CYLD MALT1	2.46e-05	2	173	2	36922488
Pubmed	TRIP13 promotes error-prone nonhomologous end joining and induces chemoresistance in head and neck cancer.	TRIP13 PRKDC	2.46e-05	2	173	2	25078033
Pubmed	A δ38 deletion variant of human transketolase as a model of transketolase-like protein 1 exhibits no enzymatic activity.	TKTL1 TKT	2.46e-05	2	173	2	23118983
Pubmed	Combining the Allosteric Inhibitor Asciminib with Ponatinib Suppresses Emergence of and Restores Efficacy against Highly Resistant BCR-ABL1 Mutants.	PRKDC C5	2.46e-05	2	173	2	31543464
Pubmed	The paracaspase MALT1 controls caspase-8 activation during lymphocyte proliferation.	CASP8 MALT1	2.46e-05	2	173	2	18691973
Pubmed	Muscle structure influences utrophin expression in mdx mice.	DES DMD	2.46e-05	2	173	2	24922526
Pubmed	Imiquimod induces a Toll-like receptor 7-independent increase in intracellular calcium via IP(3) receptor activation.	TLR7 ITPR1	2.46e-05	2	173	2	24971541
Pubmed	The expression of CYP2D22, an ortholog of human CYP2D6, in mouse striatum and its modulation in 1-methyl 4-phenyl-1,2,3,6-tetrahydropyridine-induced Parkinson's disease phenotype and nicotine-mediated neuroprotection.	CYP2D7 CYP2D6	2.46e-05	2	173	2	19594327
Pubmed	Chemokine/ITGA4 Interaction Directs iPSC-Derived Myogenic Progenitor Migration to Injury Sites in Aging Muscle for Regeneration.	PRKDC DMD	2.46e-05	2	173	2	37508502
Pubmed	Coding-noncoding gene expression in intrahepatic cholangiocarcinoma.	CYP2D7 CYP2D6	2.46e-05	2	173	2	26297049
Pubmed	A frameshift mutation and alternate splicing in human brain generate a functional form of the pseudogene cytochrome P4502D7 that demethylates codeine to morphine.	CYP2D7 CYP2D6	2.46e-05	2	173	2	15051713
Pubmed	An essential function for the calcium-promoted Ras inactivator in Fcgamma receptor-mediated phagocytosis.	RASA4 RASA4B	2.46e-05	2	173	2	16041389
Pubmed	Human circulating AC133(+) stem cells restore dystrophin expression and ameliorate function in dystrophic skeletal muscle.	PROM1 DMD	2.46e-05	2	173	2	15254585
Pubmed	Is transketolase-like protein, TKTL1, transketolase?	TKTL1 TKT	2.46e-05	2	173	2	23261987
Pubmed	Upregulating sirtuin 6 ameliorates glycolysis, EMT and distant metastasis of pancreatic adenocarcinoma with krüppel-like factor 10 deficiency.	PRKDC C5	2.46e-05	2	173	2	34702956
Pubmed	An in vivo neuroimmune organoid model to study human microglia phenotypes.	PRKDC C5	2.46e-05	2	173	2	37172564
Pubmed	HSF1 phosphorylation establishes an active chromatin state via the TRRAP-TIP60 complex and promotes tumorigenesis.	TRPC4AP VWA8 INTS7 VPS13C SYNE1 APOB PPFIA3 ITPR1 NUP205 ARPC2 DOCK5 HPS6 ULK4 DMD	2.71e-05	754	173	14	35906200
Pubmed	Large-scale concatenation cDNA sequencing.	TRPC4AP COG7 UBR4 DHX57 MALT1 DLGAP3 VPS13D EIF4A1 IQSEC1 CTNND2 RAPGEF2 DHX29	3.02e-05	568	173	12	9110174
Pubmed	Systematic Analysis of Human Protein Phosphatase Interactions and Dynamics.	INTS7 MYO9A EXPH5 SYNE1 UBR4 PPFIA3 DBT NUP205 PPP2R3A TKT PRKDC CUX1	3.28e-05	573	173	12	28330616
Pubmed	Neural-specific inactivation of ShcA results in increased embryonic neural progenitor apoptosis and microencephaly.	MAP2 CUX1 GABRA2	3.33e-05	13	173	3	16870734
Pubmed	A "double adaptor" method for improved shotgun library construction.	TRPC4AP COG7 UBR4 DHX57 MALT1 DLGAP3 VPS13D EIF4A1 IQSEC1 CTNND2 RAPGEF2 DHX29	3.34e-05	574	173	12	8619474
Pubmed	Prediction of the coding sequences of mouse homologues of KIAA gene: II. The complete nucleotide sequences of 400 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.	TNIK CYLD SYNE1 ARHGEF12 ADCY3 USP19 CHST15 CLTC VPS13B PLXNA2	4.04e-05	407	173	10	12693553
Pubmed	A dual-activity topoisomerase complex regulates mRNA translation and turnover.	PHLDB3 DIRAS1 VWA8 UBR4 HECTD4 FRYL ZZEF1 DST CHST15 RPTOR HPS6 A4GALT DIAPH2 ULK4 HMGXB3 PRKDC CYB5R2	4.04e-05	1105	173	17	35748872
Pubmed	LOXL2 Upregulates Phosphorylation of Ezrin to Promote Cytoskeletal Reorganization and Tumor Cell Invasion.	HK1 RARS1 IDE SIPA1 TKT EIF4A1 CLTC PRKDC DIRAS2	4.13e-05	327	173	9	31409639
Pubmed	Identification of dynein heavy chain genes expressed in human and mouse testis: chromosomal localization of an axonemal dynein gene.	DNAH10 DNAH5 DNAH6	4.23e-05	14	173	3	9373155
Pubmed	Chemical Crosslinking Mass Spectrometry Analysis of Protein Conformations and Supercomplexes in Heart Tissue.	HK1 VWA8 DBT CMYA5 DES DST PYGM DNAH5 VPS13B	4.54e-05	331	173	9	29199018
Pubmed	Conserved Mitotic Phosphorylation of a Proteasome Subunit Regulates Cell Proliferation.	CEP44 SLITRK5 DDX39B ANAPC4 MTSS2	5.11e-05	80	173	5	34831298
Pubmed	Mechanisms and Consequences of Dopamine Depletion-Induced Attenuation of the Spinophilin/Neurofilament Medium Interaction.	HK1 DLGAP3 CLTC IQSEC1 PYGM MTSS2	5.19e-05	131	173	6	28634551
Pubmed	Identification of potential protein interactors of Lrrk2.	LRRK2 CLTC PRKDC	5.27e-05	15	173	3	17400507
Pubmed	A Multipronged Unbiased Strategy Guides the Development of an Anti-EGFR/EPHA2-Bispecific Antibody for Combination Cancer Therapy.	TNIK PHLDB3 ABL2 GOSR1 TBC1D22B DST TFB1M DMD PLCH1 MTSS2	5.35e-05	421	173	10	36976175
Pubmed	Nonsyndromic Retinitis Pigmentosa Overview	PDE6A HK1 PROM1 MERTK CNGB1	5.42e-05	81	173	5	20301590
Pubmed	Histone methyltransferase DOT1L coordinates AR and MYC stability in prostate cancer.	EXPH5 VPS13C HECTD4 TKT EIF4A1 HPS6 CLTC GNAS	5.70e-05	264	173	8	32814769
Pubmed	HDLBP Promotes Hepatocellular Carcinoma Proliferation and Sorafenib Resistance by Suppressing Trim71-dependent RAF1 Degradation.	TNIK RARS1 VWA8 TUT7 DHX57 APOB NUP205 WDR3 TFB1M TKT A4GALT CLTC IQSEC1 ASCC2 C5 GNAS C2orf49 DDX39B DIRAS2	5.73e-05	1371	173	19	36244648
Pubmed	Impaired OTUD7A-dependent Ankyrin regulation mediates neuronal dysfunction in mouse and human models of the 15q13.3 microdeletion syndrome.	FASTKD1 DLGAP3 ELFN1 IQSEC1 SLITRK5 PYGM GABRA2	6.20e-05	197	173	7	36604605
Pubmed	Analysis of 17 autoimmune disease-associated variants in type 1 diabetes identifies 6q23/TNFAIP3 as a susceptibility locus.	ERAP1 STAT4 C5	6.46e-05	16	173	3	19110536
Pubmed	Sustained signalling by PTH modulates IP3 accumulation and IP3 receptors through cyclic AMP junctions.	ADCY3 ITPR1	7.36e-05	3	173	2	25431134
Pubmed	CD28 inhibits T cell adhesion by recruiting CAPRI to the plasma membrane.	RASA4 RASA4B	7.36e-05	3	173	2	25637021
Interaction	GAN interactions	DNAH10 SYNE1 ARHGEF12 ZZEF1 DES DST EIF4A1 ANKRD36 DMD DNAH6 DDX39B CUX1	1.57e-06	253	169	12	int:GAN
Interaction	YWHAB interactions	CYLD TICRR ABL2 MAP2 MYO9A EXPH5 LRRK2 HECTD4 TBC1D22B FRYL SIPA1 ARPC2 PIK3R4 VPS13D VIPAS39 DST CEP112 TKT CLTC MERTK RAPGEF2 PLCH1 FRMD5 MTSS2	4.21e-06	1014	169	24	int:YWHAB
Interaction	YWHAG interactions	CYLD TICRR ABL2 MAP2 MYO9A EXPH5 LRRK2 HECTD4 TBC1D22B FRYL SIPA1 PIK3R4 VPS13D DST UBE3A CEP112 RPTOR CLTC IQSEC1 PRKDC GNAS RAPGEF2 PLCH1 C2orf49 DDX39B FRMD5 MTSS2	5.30e-06	1248	169	27	int:YWHAG
Interaction	HERC2 interactions	TNIK CYLD UBR4 LRRK2 HECTD4 ARHGEF12 SIPA1 USP19 BICD1 DST UBE3A CLTC GNAS DDX39B CUX1 NIN	5.45e-06	503	169	16	int:HERC2
Interaction	YWHAQ interactions	CYLD TICRR ABL2 MAP2 MYO9A EXPH5 LRRK2 HECTD4 FRYL SIPA1 DES VPS13D DST CEP112 RPTOR CLTC NCOA1 ULK4 PRKDC MERTK RAPGEF2 PLCH1 C2orf49 FRMD5 MTSS2	7.02e-06	1118	169	25	int:YWHAQ
Interaction	OPALIN interactions	INTS7 ERAP1 FASTKD1 TRIP13 NUP205 DOCK5 RPTOR IPO13 PRKDC FRMD5	1.11e-05	209	169	10	int:OPALIN
Interaction	PLEC interactions	ARHGAP42 CYLD MAP2 MYO9A LRRK2 CASP8 URGCP ITPR1 MALT1 DST TKT RAPGEF2 DNAH5 DDX39B	1.67e-05	430	169	14	int:PLEC
Interaction	YWHAH interactions	CYLD TICRR ABL2 MAP2 MYO9A EXPH5 LRRK2 HECTD4 TBC1D22B FRYL SIPA1 PIK3R4 VPS13D DST TFB1M UBE3A CEP112 RPTOR NCOA1 RAPGEF2 PLCH1 FRMD5 MTSS2 NIN	1.69e-05	1102	169	24	int:YWHAH
Interaction	YWHAZ interactions	CYLD TICRR ABL2 MAP2 MYO9A EXPH5 LRRK2 HECTD4 TBC1D22B FRYL PPFIA3 SIPA1 ITPR1 VPS13D DST UBE3A CEP112 TKT RPTOR CLTC RAPGEF2 PLCH1 C2orf49 RUNDC1 MTSS2 NIN	4.03e-05	1319	169	26	int:YWHAZ
Interaction	CDKL5 interactions	TNIK DLGAP3 ELFN1 IQSEC1 SLITRK5 CTNND2 GABRA2	4.72e-05	113	169	7	int:CDKL5
Interaction	SYNGAP1 interactions	ARHGAP42 TNIK MAP2 DLGAP3 ELFN1 CEP44 CLTC IQSEC1 GNAS RAPGEF2 DHX29	5.87e-05	307	169	11	int:SYNGAP1
Interaction	AGAP2 interactions	TNIK CACNB3 ABL2 SYNE1 DLGAP3 CLTC IQSEC1 GNAS RAPGEF2	7.23e-05	210	169	9	int:AGAP2
Interaction	CIT interactions	TNIK CYLD RARS1 VWA8 USP28 SYNE1 UBR4 LRRK2 DHX57 APOB CMYA5 ZZEF1 TRIP13 BICD1 NUP205 WDR3 DES TFB1M ELFN1 EIF4A1 CLTC PRKDC GNAS DDX39B CUX1 FRMD5 NIN	7.46e-05	1450	169	27	int:CIT
Interaction	SLC6A4 interactions	TNIK MYO9A VPS13C PPFIA3 ARPC2 DLGAP3 TFB1M ELFN1 RPTOR IQSEC1 RAPGEF2 DIRAS2 MTSS2	8.43e-05	437	169	13	int:SLC6A4
Interaction	GRIA1 interactions	TNIK CYLD CASP8 DLGAP3 UNC45B ELFN1	8.59e-05	86	169	6	int:GRIA1
Interaction	KCTD13 interactions	HK1 MAP2 MYO9A SYNE1 ARHGEF12 DHX57 PPFIA3 SIPA1 RTN1 ARPC2 PIK3R4 DLGAP3 DST TKT RPTOR CLTC IQSEC1 DMD CTNND2 RAPGEF2 PLCH1 DNAH6 DHX29 DDX39B MTUS2 DIRAS2	1.00e-04	1394	169	26	int:KCTD13
Interaction	MUC19 interactions	CYLD RPTOR DRC3	1.21e-04	12	169	3	int:MUC19
Interaction	GPR182 interactions	ERAP1 GOSR1 FASTKD1 TRIP13 NUP205 PIK3R4 DOCK5 LIPE IPO13 PRKDC ZW10 CUX1 DGAT1	1.26e-04	455	169	13	int:GPR182
Interaction	GSK3B interactions	TNIK CYLD HK1 RARS1 VWA8 ERAP1 MYO9A LRRK2 ARHGEF12 RTN1 BICD1 NUP205 VPS13D DST UBE3A CLTC PRKDC CTNND2 NIN	1.28e-04	868	169	19	int:GSK3B
GeneFamily	Dyneins, axonemal	DNAH10 DNAH5 DNAH6 DNAH9	3.97e-06	17	119	4	536
GeneFamily	Non-canonical poly(A) polymerases	TENT4B TUT7	8.83e-04	7	119	2	1318
Coexpression	LAKE_ADULT_KIDNEY_C2_PODOCYTES	EXPH5 ARHGEF12 CMYA5 ATP10A BICD1 DOCK5 DST CEP112 NCOA1 ANKRD36	1.56e-06	212	173	10	M39221
Coexpression	GSE3982_NKCELL_VS_TH1_UP	EXPH5 APOB RTN1 URGCP PPP2R3A CHST15 FAM186A IQSEC1 NCOA1	6.29e-06	195	173	9	M5593
Coexpression	GSE7348_LPS_VS_TOLERIZED_AND_LPS_STIM_MACROPHAGE_DN	CYLD RARS1 TUT7 CASP8 TBC1D22B ITPR1 LIPE RUNDC1	2.14e-05	174	173	8	M6850
Coexpression	HE_LIM_SUN_FETAL_LUNG_C0_PERICYTE	ARHGAP42 PHLDB3 MAP2 ARHGEF12 ADCY3 NECAB1 DMD MTSS2	4.82e-05	195	173	8	M45684
Coexpression	GSE16450_CTRL_VS_IFNA_12H_STIM_IMMATURE_NEURON_CELL_LINE_UP	TNIK ABL2 VWA8 HECTD4 ATP10A VPS13D DIAPH2 VPS13B	5.18e-05	197	173	8	M7403
Coexpression	GSE5589_UNSTIM_VS_180MIN_LPS_AND_IL10_STIM_MACROPHAGE_DN	CYLD HK1 SIPA1 STAT4 PROM1 CTNND2 RAPGEF2 NIN	5.56e-05	199	173	8	M6605
Coexpression	GSE45881_CXCR6HI_VS_CXCR1LO_COLONIC_LAMINA_PROPRIA_UP	TNIK RARS1 UBR4 ZZEF1 STAT4 NUP205 IQSEC1 ANKRD36	5.76e-05	200	173	8	M9889
Coexpression	GSE18804_SPLEEN_MACROPHAGE_VS_COLON_TUMORAL_MACROPHAGE_DN	USP28 CMYA5 URGCP DES UNC45B IPO13 PYGM DMD	5.76e-05	200	173	8	M10033
CoexpressionAtlas	FacebaseRNAseq_e8.5_Non-Floor Plate Neural Epithelium_top-relative-expression-ranked_2500_k-means-cluster#5	DIRAS1 MAP2 SLC36A4 VWA8 HECTD4 RTN1 BICD1 GSTZ1 PROM1 DST CHST15 CBX6 CEP112 IQSEC1 SLITRK5 NCOA1 DMD PLXNA2 FRMD5	6.82e-06	732	170	19	Facebase_RNAseq_e8.5_Non-Floor Plate Neural Epithelium_2500_K5
ToppCell	Ciliated-cil-3\|World / Class top	DNAH10 SYNE1 RFX2 C20orf96 CCDC78 ULK4 DNAH5 DNAH6 DNAH9 DRC3	4.40e-09	192	173	10	4989ebb8812b8af1870599acd932849122c05a29
ToppCell	IPF-Epithelial-Ciliated\|Epithelial / Disease state, Lineage and Cell class	DNAH10 SYNE1 CCDC78 ULK4 DMD PLCH1 DNAH5 DNAH6 DNAH9 DRC3	4.63e-09	193	173	10	ad58f5080e0ba65c845056ea6b79037b636e9c64
ToppCell	3'-Broncho-tracheal-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.3.0\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	DNAH10 ABCA13 SYNE1 PROM1 CCDC78 ULK4 DNAH5 DNAH6 DNAH9 DRC3	4.86e-09	194	173	10	4a2c127c90d1fefe604fcb9e796577d21b489dd6
ToppCell	moderate-Epithelial-Ciliated\|Epithelial / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls	DNAH10 SYNE1 RFX2 C20orf96 CCDC78 DIAPH2 DNAH5 DNAH6 DNAH9 DRC3	5.11e-09	195	173	10	3486eae5fdb062a75a907b896c9d7b396d2aa195
ToppCell	(05)_Ciliated\|World / shred by cell type and Timepoint	TCTE1 DNAH10 SYNE1 C20orf96 CCDC78 DNAH5 DNAH6 DNAH9 DIRAS2 DRC3	5.63e-09	197	173	10	fee3cd16af8eea697cd64e8f64af505aaa2ac4b0
ToppCell	severe-low-quality_cells\|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class	TNIK CYLD SYNE1 CASP8 FRYL STAT4 SLFN12L ELFN1 ANKRD36 DDX39B	5.63e-09	197	173	10	57ebd552f10d6278623b52a3d484d4b91ae1d028
ToppCell	NS-moderate-d_0-4-Epithelial-Ciliated\|d_0-4 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	DNAH10 SYNE1 RFX2 PROM1 CCDC78 DIAPH2 DNAH5 DNAH6 DNAH9 DRC3	5.63e-09	197	173	10	71fea4aa6ce96c7693fa94792d08770622873850
ToppCell	critical-Epithelial-Ciliated\|Epithelial / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls	DNAH10 SYNE1 RFX2 C20orf96 CCDC78 DIAPH2 DNAH5 DNAH6 DNAH9 DRC3	5.91e-09	198	173	10	ee2c8385c0bf4ea9f5c9517b52cf131af3fbdd40
ToppCell	LPS_only-Epithelial_airway-airway_epithelial-Ciliated\|LPS_only / Treatment groups by lineage, cell group, cell type	TCTE1 DNAH10 RTN1 TTC6 CCDC78 PLCH1 DNAH5 DNAH6 DNAH9 DRC3	5.91e-09	198	173	10	6d90b541fde357fbb40f8f7d4e8628a48b679718
ToppCell	facs-Trachea-3m-Epithelial-airway_epithelial-tracheobronchial_ciliated_cell-ciliated_cell\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	TCTE1 DNAH10 PROM1 C20orf96 CCDC78 PLCH1 DNAH5 DNAH6 DNAH9	3.28e-08	177	173	9	3cfde67b93f3986312f5e74e42504214d966e7dc
ToppCell	facs-Trachea-3m-Epithelial-airway_epithelial-tracheobronchial_ciliated_cell\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	TCTE1 DNAH10 PROM1 C20orf96 CCDC78 PLCH1 DNAH5 DNAH6 DNAH9	3.28e-08	177	173	9	12a52a12a87a31e501ced611f46a90d172ca7e35
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic-thymocyte\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DNAH10 ABCA12 ABCA13 LAMA1 APOB DMD PLCH1 DNAH5 DNAH9	4.58e-08	184	173	9	2cbed6462fea2622871bb7e49b0df3d984239281
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DNAH10 ABCA12 ABCA13 LAMA1 APOB DMD PLCH1 DNAH5 DNAH9	4.58e-08	184	173	9	ea7a7e2bac46d4d2c31a5d576b38a032b5335062
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic-proliferating_thymocyte;_DN_to_DP_transition,_dividing_(some_are_Cd8+/_Cd4+,_some_undergoing_VDJ_recombination)\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DNAH10 ABCA12 ABCA13 LAMA1 APOB DMD PLCH1 DNAH5 DNAH9	4.58e-08	184	173	9	2b19a8c5f823e00812908b23e66bb4e563278aff
ToppCell	COPD-Epithelial-Ciliated\|COPD / Disease state, Lineage and Cell class	DNAH10 ABCA13 PROM1 CCDC78 PLCH1 DNAH5 DNAH6 DNAH9 DRC3	5.26e-08	187	173	9	f0fd0792f6926f705d175f6e6fd480f12c7a3bd4
ToppCell	COPD-Epithelial-Ciliated\|Epithelial / Disease state, Lineage and Cell class	DNAH10 ABCA13 CCDC78 ULK4 PLCH1 DNAH5 DNAH6 DNAH9 DRC3	5.76e-08	189	173	9	3e77883db34722b9ce0a03ea74caefc92dc7feff
ToppCell	facs-Lung-18m-Epithelial-airway_epithelial-lung_ciliated_cell-ciliated_cell\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	TCTE1 DNAH10 C20orf96 CCDC78 PLCH1 DNAH5 DNAH6 DNAH9 DRC3	6.03e-08	190	173	9	9ffd18ef358f8e32c610ab6420f479067c8ba44b
ToppCell	Nasal_Brush-Epithelial-Ciliated_2\|Nasal_Brush / Tissue, Lineage and Cell class of Lung Cells from 10X	DNAH10 SYNE1 RFX2 C20orf96 CCDC78 DNAH5 DNAH6 DNAH9 DRC3	6.03e-08	190	173	9	9ce7df056bfb24d70db4c3c4a2c57d89115de877
ToppCell	facs-Lung-18m-Epithelial-airway_epithelial-lung_ciliated_cell\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	TCTE1 DNAH10 C20orf96 CCDC78 PLCH1 DNAH5 DNAH6 DNAH9 DRC3	6.03e-08	190	173	9	3ef39d61c98de4e5df946b995847aa65eba6a4b6
ToppCell	Nasal_Brush-Epithelial-Ciliated_2\|Epithelial / Tissue, Lineage and Cell class of Lung Cells from 10X	DNAH10 SYNE1 RFX2 C20orf96 CCDC78 DNAH5 DNAH6 DNAH9 DRC3	6.03e-08	190	173	9	833481ace2800354712e2ce709d5cdfd0aed3d42
ToppCell	BAL-Mild-Epithelial-Epithelial-Ciliated-\|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)	DNAH10 ABCA13 PROM1 CCDC78 PLCH1 DNAH5 DNAH6 DNAH9 DRC3	6.31e-08	191	173	9	2a8e6d560907e71e9f6e190ca0667da804e25641
ToppCell	BAL-Mild-Epithelial-Epithelial-Ciliated-\|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	DNAH10 ABCA13 PROM1 CCDC78 PLCH1 DNAH5 DNAH6 DNAH9 DRC3	6.31e-08	191	173	9	46c9d4d10c66c0fae1fa351924091b69ea2f38d4
ToppCell	LA-03._Atrial_Cardiomyocyte\|LA / Chamber and Cluster_Paper	USP28 CMYA5 STAT4 DES PPP2R3A DMD CTNND2 MTUS2 FRMD5	6.31e-08	191	173	9	5d1b674eb7703830b7ce8bbeac3363cabd0e6ae9
ToppCell	Mild_COVID-19-Epithelial-Ciliated\|Mild_COVID-19 / Disease group,lineage and cell class （2021.01.30）	DNAH10 ABCA13 PROM1 CCDC78 PLCH1 DNAH5 DNAH6 DNAH9 DRC3	6.31e-08	191	173	9	995e76bbf07674d95b8ef09e078cf6410af27a09
ToppCell	BAL-Mild-Epithelial-Epithelial-Ciliated\|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	DNAH10 ABCA13 PROM1 CCDC78 PLCH1 DNAH5 DNAH6 DNAH9 DRC3	6.31e-08	191	173	9	a37f20172b85566b9039254a89680e37fd503fd5
ToppCell	BAL-Mild-Epithelial-Epithelial-Ciliated\|Mild / Location, Disease Group, Cell group, Cell class (2021.03.09)	DNAH10 ABCA13 PROM1 CCDC78 PLCH1 DNAH5 DNAH6 DNAH9 DRC3	6.31e-08	191	173	9	2d36e08c5629cf73b6dd02cd173cafb52e8a3a7d
ToppCell	Bronchial_Biopsy-Epithelial-Ciliated_1\|Bronchial_Biopsy / Tissue, Lineage and Cell class of Lung Cells from 10X	DNAH10 SYNE1 PROM1 C20orf96 CCDC78 DNAH5 DNAH6 DNAH9 DRC3	6.59e-08	192	173	9	be592e661367affced9ebe80849b466e6adb3a34
ToppCell	BALF-PFMC-Severe-critical_progression_d12-22_no-steroids-Epithelial-Epithelial,_Airway-ciliated_cell\|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)	DNAH10 ABCA13 RFX2 PROM1 C20orf96 CCDC78 DNAH5 DNAH6 DNAH9	6.59e-08	192	173	9	03acd4a26b986e34eee608747347791122f1aa52
ToppCell	BALF-PFMC-Severe-critical_progression_d12-22_no-steroids-Epithelial-Epithelial,_Airway-ciliated_cell-Epi-Ciliated\|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)	DNAH10 ABCA13 RFX2 PROM1 C20orf96 CCDC78 DNAH5 DNAH6 DNAH9	6.59e-08	192	173	9	31c6046589e2fbb0486fd044c5b128099d37872f
ToppCell	COPD-Epithelial-Ciliated\|World / Disease state, Lineage and Cell class	DNAH10 ABCA13 PROM1 CCDC78 PLCH1 DNAH5 DNAH6 DNAH9 DRC3	6.59e-08	192	173	9	eab1105cd1a98cfcd3d74dc5c9b89e1799bba59e
ToppCell	Bronchial_Biopsy-Epithelial-Ciliated_1\|Epithelial / Tissue, Lineage and Cell class of Lung Cells from 10X	DNAH10 SYNE1 PROM1 C20orf96 CCDC78 DNAH5 DNAH6 DNAH9 DRC3	6.89e-08	193	173	9	0b62a6ddd7c42efd9f39781971d1438501e1fa8d
ToppCell	IPF-Multiplet-Multiplet\|IPF / Disease state, Lineage and Cell class	ARHGAP42 DNAH10 SYNE1 ARHGEF12 CEP112 PLCH1 DNAH5 DNAH6 DNAH9	7.53e-08	195	173	9	fce0c29574bb7aab181b9c00feb42681e285d1f2
ToppCell	IPF-Multiplet\|IPF / Disease state, Lineage and Cell class	ARHGAP42 DNAH10 SYNE1 ARHGEF12 CEP112 PLCH1 DNAH5 DNAH6 DNAH9	7.53e-08	195	173	9	eacc0449ae6f3ad8002268cd061467684c6fb9a7
ToppCell	5'-Airway_Nasal-Epithelial-Airway_ciliated\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	DNAH10 ABCA13 SYNE1 PROM1 CCDC78 DNAH5 DNAH6 DNAH9 DRC3	8.22e-08	197	173	9	91637bdeab85024b5a02d1066f76cb803a2d6420
ToppCell	5'-Airway_Nasal-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	DNAH10 ABCA13 SYNE1 PROM1 CCDC78 DNAH5 DNAH6 DNAH9 DRC3	8.22e-08	197	173	9	22c87dd15dc57bd0aa98a204c9fc9b3b9b573b45
ToppCell	3'-Parenchyma_lung-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.2.2\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	DNAH10 SYNE1 CCDC78 ULK4 DMD DNAH5 DNAH6 DNAH9 DRC3	8.22e-08	197	173	9	74a2c6cb8fcfe53dd9a2b36492a16c58f38e51c9
ToppCell	5'-Airway_Nasal-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.0.0\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	DNAH10 ABCA13 SYNE1 PROM1 CCDC78 DNAH5 DNAH6 DNAH9 DRC3	8.22e-08	197	173	9	3bbf068d2ad8196fbc85d3f311a7c54c9aece856
ToppCell	control-Epithelial-Ciliated\|Epithelial / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls	DNAH10 SYNE1 PROM1 CCDC78 DIAPH2 DNAH5 DNAH6 DNAH9 DRC3	8.22e-08	197	173	9	e453d085182364ca347cbcc9dc995c62c3353016
ToppCell	5'-Airway_Nasal-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	DNAH10 ABCA13 SYNE1 PROM1 CCDC78 DNAH5 DNAH6 DNAH9 DRC3	8.22e-08	197	173	9	87db09f341e2b20eb6e1c3e917cb5c960387b3e9
ToppCell	COVID-19-Epithelial\|COVID-19 / Condition, Lineage and Cell class	DNAH10 ABCA13 EXPH5 PROM1 CCDC78 DNAH5 DNAH6 DNAH9 DRC3	8.22e-08	197	173	9	18fd7344628a87d5c7ef5efb66e260a4136245bf
ToppCell	control-Epithelial-Ciliated\|control / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls	DNAH10 SYNE1 PROM1 CCDC78 DIAPH2 DNAH5 DNAH6 DNAH9 DRC3	8.22e-08	197	173	9	d4e963c1f82996371bf3d63578ee9fce8e00c5a8
ToppCell	LPS_IL1RA_TNF-Epithelial_airway-airway_epithelial-Ciliated\|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type	TCTE1 DNAH10 TTC6 PROM1 CCDC78 DNAH5 DNAH6 DNAH9 DRC3	9.35e-08	200	173	9	96701a4d57753f5ec0dd5c7550054bbcc946bc5f
ToppCell	3'-Broncho-tracheal-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.0.2\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	DNAH10 ABCA13 PROM1 CCDC78 DNAH5 DNAH6 DNAH9 DRC3	3.35e-07	169	173	8	14aadc2d1bf66eb47dac33b4d61ddb3c942caa4f
ToppCell	3'-Distal_airway-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.3.0\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	DNAH10 ABCA13 PROM1 CCDC78 DNAH5 DNAH6 DNAH9 DRC3	4.00e-07	173	173	8	c3762655caa79ac4879876f470d32578a3c93b01
ToppCell	PND07-28-samps-Epithelial-Epithelial-non_alveolar-Ciliated_cell_of_lung_parenchyma\|PND07-28-samps / Age Group, Lineage, Cell class and subclass	DNAH10 C20orf96 ULK4 PLCH1 DNAH5 DNAH6 DNAH9 DRC3	4.18e-07	174	173	8	f41d05a3703d7092bd3c4a97c15ae13069aaa4ad
ToppCell	PND07-28-samps-Epithelial-Epithelial-non_alveolar\|PND07-28-samps / Age Group, Lineage, Cell class and subclass	DNAH10 C20orf96 ULK4 PLCH1 DNAH5 DNAH6 DNAH9 DRC3	4.37e-07	175	173	8	c01a15b2084da4a18f8ff3623f44eb9dfe499f10
ToppCell	facs-Trachea-nan-3m-Epithelial-ciliated_columnar_cell_of_tracheobronchial_tree\|Trachea / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TCTE1 DNAH10 C20orf96 CCDC78 PLCH1 DNAH5 DNAH6 DNAH9	5.41e-07	180	173	8	cf6e9f757afeb342c5023f6e6152a1b4d0d164b4
ToppCell	5'-Airway_Nasal-Epithelial-Airway_ciliated-multi-ciliated_epithelial_cell-Multiciliated_(nasal)-Multiciliated_(nasal)_L.0.3.1.1\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	DNAH10 ABCA13 PROM1 CCDC78 DNAH5 DNAH6 DNAH9 DRC3	5.41e-07	180	173	8	1f1af4474f3f0ac3c0d6b1a6c875c354d36d8eec
ToppCell	Control-Epithelial_cells-Airway_ciliated\|Control / group, cell type (main and fine annotations)	DNAH10 ABCA13 PROM1 CCDC78 DNAH5 DNAH6 DNAH9 DRC3	5.88e-07	182	173	8	fb725d10d9ed25dfc6d5bb69cfef78513f7d3e8f
ToppCell	facs-Lung-EPCAM-24m-Epithelial-ciliated_columnar_cell_of_tracheobronchial_tree\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DNAH10 C20orf96 CCDC78 ULK4 DNAH5 DNAH6 DNAH9 DRC3	6.39e-07	184	173	8	afb11ab301ef9801333dbb53ccff4bd0d44f1677
ToppCell	facs-Lung-EPCAM-24m-Epithelial-Ciliated_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DNAH10 C20orf96 CCDC78 ULK4 DNAH5 DNAH6 DNAH9 DRC3	6.39e-07	184	173	8	a411c0bcb283534a1c15f22473c46b7d87e01294
ToppCell	CV-Moderate-7\|Moderate / Virus stimulation, Condition and Cluster	VPS13C FRYL SLC10A7 SLFN12L RASA4 MCM9 CLTC PRKDC	6.65e-07	185	173	8	a6c9203ce6c2892a4a369c9bcfb85720f01cbb3f
ToppCell	COVID-19-Epithelial_cells-Airway_ciliated\|COVID-19 / group, cell type (main and fine annotations)	DNAH10 ABCA13 PROM1 CCDC78 DNAH5 DNAH6 DNAH9 DRC3	6.65e-07	185	173	8	18a40f0a338aa398d81384b5159fb80ce8a2020c
ToppCell	CV-Moderate-7\|CV / Virus stimulation, Condition and Cluster	VPS13C FRYL SLC10A7 SLFN12L RASA4 MCM9 CLTC PRKDC	6.93e-07	186	173	8	8571956890fc9894d766ba294a28e376b4aba428
ToppCell	Ciliated-cil-2\|World / Class top	DNAH10 C20orf96 CCDC78 ULK4 DNAH5 DNAH6 DNAH9 DRC3	7.21e-07	187	173	8	e2e58ba039b5355c03c3b448e750aa37b0ea6913
ToppCell	droplet-Lung-3m-Epithelial-airway_epithelial-lung_ciliated_cell-ciliated_cell\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	TCTE1 DNAH10 C20orf96 CCDC78 DNAH5 DNAH6 DNAH9 DRC3	7.21e-07	187	173	8	1bba994aaaa9825b54aaeaff3829850267bc4602
ToppCell	droplet-Lung-3m-Epithelial-airway_epithelial-lung_ciliated_cell\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	TCTE1 DNAH10 C20orf96 CCDC78 DNAH5 DNAH6 DNAH9 DRC3	7.21e-07	187	173	8	d6ac351e7aeba98851d308c14ac395044fe4fbbb
ToppCell	Ciliated\|World / Class top	DNAH10 C20orf96 CCDC78 ULK4 DNAH5 DNAH6 DNAH9 DRC3	7.51e-07	188	173	8	cc9178361360b5800f96516ed6a65089c144b1ce
ToppCell	Epithelial-Epithelial-D_(Ciliated)\|Epithelial / shred on cell class and cell subclass (v4)	DNAH10 SYNE1 C20orf96 CCDC78 DNAH5 DNAH6 DNAH9 DRC3	7.51e-07	188	173	8	8f30535a32968a81a304315a49c0d90a77d36948
ToppCell	PND07-Epithelial-Epithelial_Airway-Ciliated/Deuterosomal-Ciliated-Ciliated_mature\|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	TCTE1 DNAH10 C20orf96 CCDC78 DNAH5 DNAH6 DNAH9 DRC3	7.82e-07	189	173	8	057d7a03fdbe779122b203619a6f947f49b84d28
ToppCell	droplet-Lung-immune-endo-depleted-3m-Epithelial-ciliated_columnar_cell_of_tracheobronchial_tree\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TCTE1 DNAH10 C20orf96 CCDC78 DNAH5 DNAH6 DNAH9 DRC3	7.82e-07	189	173	8	28c750ac56e3861fe7280e32839a4d8ce8bd8692
ToppCell	droplet-Lung-immune-endo-depleted-3m-Epithelial-Ciliated_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TCTE1 DNAH10 C20orf96 CCDC78 DNAH5 DNAH6 DNAH9 DRC3	7.82e-07	189	173	8	efee01edd171bf569267b672fab05c421de6c92d
ToppCell	droplet-Lung-3m-Epithelial-airway_epithelial\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	TCTE1 DNAH10 C20orf96 CCDC78 DNAH5 DNAH6 DNAH9 DRC3	7.82e-07	189	173	8	a28e0922e10013ae79266f6a3f9305e6ee614d8b
ToppCell	PND07-Epithelial-Epithelial_Airway-Ciliated/Deuterosomal\|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	TCTE1 DNAH10 C20orf96 CCDC78 DNAH5 DNAH6 DNAH9 DRC3	7.82e-07	189	173	8	9f57a131902d23494bf389baf6e6e2d99f88b2c8
ToppCell	5'-Airway_Nasal-Epithelial-Airway_ciliated-multi-ciliated_epithelial_cell-Multiciliated_(nasal)\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	DNAH10 ABCA13 PROM1 CCDC78 DNAH5 DNAH6 DNAH9 DRC3	7.82e-07	189	173	8	b4b93bd10b7e3cc16e54ff73beac230f519c010a
ToppCell	droplet-Lung-18m-Epithelial-airway_epithelial\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	TCTE1 DNAH10 C20orf96 CCDC78 DNAH5 DNAH6 DNAH9 DRC3	7.82e-07	189	173	8	fe958fdf9963c2dfe270f67f0da36b3264d0017c
ToppCell	COVID-19-lung-Ciliated\|lung / Disease (COVID-19 only), tissue and cell type	DNAH10 ABCA13 PROM1 CCDC78 DNAH5 DNAH6 DNAH9 DRC3	7.82e-07	189	173	8	27329c4661aebabd19fac7fe5dca263fe99d76f3
ToppCell	PND07-Epithelial-Epithelial_Airway-Ciliated/Deuterosomal-Ciliated\|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	TCTE1 DNAH10 C20orf96 CCDC78 DNAH5 DNAH6 DNAH9 DRC3	7.82e-07	189	173	8	e443b02502edaefa94567a9e8af5756e8e11ff30
ToppCell	BAL-Control-Epithelial-Epithelial-Ciliated\|Control / Location, Disease Group, Cell group, Cell class (2021.03.09)	DNAH10 ABCA13 PROM1 CCDC78 DNAH5 DNAH6 DNAH9 DRC3	8.46e-07	191	173	8	7b5da29109aa28768c67653a1bc0f385c2d2269b
ToppCell	BAL-Control-Epithelial\|Control / Location, Disease Group, Cell group, Cell class (2021.03.09)	DNAH10 ABCA13 PROM1 CCDC78 DNAH5 DNAH6 DNAH9 DRC3	8.46e-07	191	173	8	9f19098f260d5542aa8ba7eb6f91b44d0db6e0a4
ToppCell	renal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Intermediate_tubule_epithelial_cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	MYO9A ABCA13 LAMA1 LRRK2 BICD1 PROM1 PPP2R3A DNAH5	8.46e-07	191	173	8	d0e9afe7b6334dd515d3e68892efdc76347a55e5
ToppCell	BAL-Control-Epithelial-Epithelial-Ciliated-\|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	DNAH10 ABCA13 PROM1 CCDC78 DNAH5 DNAH6 DNAH9 DRC3	8.46e-07	191	173	8	fa9f8b50bfc7911c858bc2f9dcd204873d97ac61
ToppCell	BAL-Control-Epithelial-Epithelial-Ciliated-\|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)	DNAH10 ABCA13 PROM1 CCDC78 DNAH5 DNAH6 DNAH9 DRC3	8.46e-07	191	173	8	b4e335e798c9617356b8e24412f9270c42dce656
ToppCell	BAL-Control-Epithelial-Epithelial-Ciliated\|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	DNAH10 ABCA13 PROM1 CCDC78 DNAH5 DNAH6 DNAH9 DRC3	8.46e-07	191	173	8	c4b223b33c020a064f576711a3d700eb60a2d737
ToppCell	BAL-Control-Epithelial\|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	DNAH10 ABCA13 PROM1 CCDC78 DNAH5 DNAH6 DNAH9 DRC3	8.46e-07	191	173	8	5129f778a9283bfac4ff322c21c5ca71da4b7174
ToppCell	BAL-Control-Epithelial-Epithelial\|Control / Location, Disease Group, Cell group, Cell class (2021.03.09)	DNAH10 ABCA13 PROM1 CCDC78 DNAH5 DNAH6 DNAH9 DRC3	8.46e-07	191	173	8	df8a1a6e78aa0cb941b94cb676bd6891d79f3687
ToppCell	nucseq-Epithelial-Epithelial_Airway-Ciliated/Deuterosomal-Ciliated\|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	DNAH10 ABCA13 PROM1 CCDC78 DNAH5 DNAH6 DNAH9 DRC3	8.46e-07	191	173	8	e417bf491f8b8d7838a61f7f4f6b1740ba97aa3f
ToppCell	Control-Epithelial\|Control / Disease group,lineage and cell class （2021.01.30）	DNAH10 ABCA13 PROM1 CCDC78 DNAH5 DNAH6 DNAH9 DRC3	8.46e-07	191	173	8	b78547dae8328244a47c83346447bdd787efbcae
ToppCell	nucseq-Epithelial-Epithelial_Airway-Ciliated/Deuterosomal\|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	DNAH10 ABCA13 PROM1 CCDC78 DNAH5 DNAH6 DNAH9 DRC3	8.46e-07	191	173	8	9d31c8424d35bdc0c27188b68bfd0f731af3600b
ToppCell	BAL-Control-Epithelial-Epithelial\|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	DNAH10 ABCA13 PROM1 CCDC78 DNAH5 DNAH6 DNAH9 DRC3	8.46e-07	191	173	8	c50d6a1a6209ed4157f7c00fc24d4ecb43790f44
ToppCell	Control-Epithelial-Ciliated\|Control / Disease group,lineage and cell class （2021.01.30）	DNAH10 ABCA13 PROM1 CCDC78 DNAH5 DNAH6 DNAH9 DRC3	8.46e-07	191	173	8	cdc08e95a0c8f5c7a8d01b6bbaafdb54ef2f0d12
ToppCell	nucseq-Epithelial-Epithelial_Airway\|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	DNAH10 ABCA13 PROM1 CCDC78 DNAH5 DNAH6 DNAH9 DRC3	8.46e-07	191	173	8	1c528f72c9ef3ef3a850b05e4a9715190832270c
ToppCell	3'-Broncho-tracheal-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.3.1\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	DNAH10 TRIP13 PROM1 C20orf96 CCDC78 DNAH5 DNAH6 DRC3	8.80e-07	192	173	8	1b6cac8156e608061e1405e36e18d185b6fa8f6f
ToppCell	3'-Broncho-tracheal-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.3.3\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	DNAH10 ABCA13 PROM1 C20orf96 CCDC78 DNAH5 DNAH6 DNAH9	9.15e-07	193	173	8	e1b76102f812c433195d1e8811fdd3293a7bc22e
ToppCell	Control-Epithelial-Ciliated\|Epithelial / Disease state, Lineage and Cell class	DNAH10 ABCA13 CCDC78 ULK4 DNAH5 DNAH6 DNAH9 DRC3	9.15e-07	193	173	8	0e37d454f3735edd936ee9a5f5f516ac3aad400e
ToppCell	NS-moderate-d_0-4\|moderate / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	DNAH10 ABCA13 EXPH5 DNAH5 DNAH6 DNAH9 PLXNA2 DRC3	9.15e-07	193	173	8	ea345d34440b25f65358a53dc72831998d1c3620
ToppCell	15-Trachea-Epithelial-Multiciliated_cell\|Trachea / Age, Tissue, Lineage and Cell class	DNAH10 RFX2 TRIP13 CCDC78 DNAH5 DNAH6 DNAH9 DRC3	9.15e-07	193	173	8	aa3acc7571405169efb656d214f3a8cbf988362e
ToppCell	severe-low-quality_cells\|severe / Cohort 1 (10x PBMC) with disease condition, cell group and cell class	TNIK SYNE1 FRYL STAT4 SLFN12L ELFN1 ANKRD36 VPS13B	9.15e-07	193	173	8	9337bc93e3904c7fc7c93c328518bcd6453b1e8c
ToppCell	3'-Parenchyma_lung-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.2.3\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	DNAH10 SYNE1 LRRK2 NECAB1 CCDC78 DNAH5 DNAH6 DRC3	9.15e-07	193	173	8	bdb7401dd9059032f930f2b575f2ef8e504b6594
ToppCell	wk_20-22-Epithelial-Proximal_epithelial-MUC16+_ciliated\|wk_20-22 / Celltypes from embryonic and fetal-stage human lung	DNAH10 ABCA13 PROM1 CCDC78 DNAH5 DNAH6 DNAH9 DRC3	9.52e-07	194	173	8	756082a0f5953b52229bb60d40b84701cb6cb23d
ToppCell	Control-Epithelial-Ciliated\|World / Disease state, Lineage and Cell class	DNAH10 ABCA13 CCDC78 PLCH1 DNAH5 DNAH6 DNAH9 DRC3	9.52e-07	194	173	8	958e648138676d46698090b4046cb484083ae449
ToppCell	COVID-19-Epithelial-Ciliated_cells\|COVID-19 / Condition, Lineage and Cell class	DNAH10 ABCA13 PROM1 CCDC78 DNAH5 DNAH6 DNAH9 DRC3	9.52e-07	194	173	8	43be5fbd51dd58839cb03ca3ddd05a458e1ddb74
ToppCell	3'-Airway_Nasal-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	DNAH10 ABCA13 PROM1 CCDC78 DNAH5 DNAH6 DNAH9 DRC3	9.89e-07	195	173	8	649fd2336e963f6a150d182a53ad5dd838ca80b1
ToppCell	NS-critical-LOC-Epithelial-Ciliated\|LOC / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	DNAH10 ABCA13 PROM1 CCDC78 DNAH5 DNAH6 DNAH9 DRC3	9.89e-07	195	173	8	34e37cff4849696ca4ba5dd8fd2cf98fed8bc912
ToppCell	3'-Airway_Nasal-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	DNAH10 ABCA13 PROM1 CCDC78 DNAH5 DNAH6 DNAH9 DRC3	9.89e-07	195	173	8	129ad5f4253ecb1a8477cc38773e6e91ea9570b0
ToppCell	3'-Airway_Nasal-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.0.0\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	DNAH10 ABCA13 PROM1 CCDC78 DNAH5 DNAH6 DNAH9 DRC3	9.89e-07	195	173	8	3e70ee987d66d450062d5df3d7c733ccc7344470
ToppCell	moderate-Epithelial-Ciliated\|moderate / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls	DNAH10 RFX2 C20orf96 CCDC78 DNAH5 DNAH6 DNAH9 DRC3	9.89e-07	195	173	8	e80f5cdf0b18066b3e6c2f5452e58f101c67932c
ToppCell	Control_saline-Epithelial_airway-airway_epithelial-Ciliated\|Control_saline / Treatment groups by lineage, cell group, cell type	DNAH10 RFX2 TTC6 CCDC78 DNAH5 DNAH6 DNAH9 DRC3	9.89e-07	195	173	8	60067b5359174f0d1a8b5748bfc0690762e9e740
ToppCell	COVID-19-Epithelial-Ciliated_cells\|Epithelial / Condition, Lineage and Cell class	DNAH10 PROM1 C20orf96 CCDC78 DNAH5 DNAH6 DNAH9 DRC3	1.03e-06	196	173	8	de7aa31354b019d7321a8ef965d59ce2e8b89276
ToppCell	COPD-Multiplet-Multiplet\|COPD / Disease state, Lineage and Cell class	ARHGAP42 ABCA13 SYNE1 ARHGEF12 PLCH1 DNAH5 DNAH6 DNAH9	1.03e-06	196	173	8	af4cdc61830685a888a1209826c23bcf54a43084
Drug	0179445-0000 [211246-22-9]; Down 200; 10uM; MCF7; HT_HG-U133A	INTS7 TUT7 FASTKD1 HECTD4 DHX57 VPS13D PPP2R3A CHST15 PLCH1 VPS13B	1.43e-06	185	171	10	4755_DN
Disease	autosomal recessive spinocerebellar ataxia 4 (implicated_via_orthology)	VPS13C VPS13D	9.52e-05	3	167	2	DOID:0111611 (implicated_via_orthology)
Disease	Cohen syndrome (implicated_via_orthology)	VPS13C VPS13B	9.52e-05	3	167	2	DOID:0111590 (implicated_via_orthology)
Disease	Malignant neoplasm of breast	KDM3A CYP2D6 SYNE1 UBR4 CASP8 RFX2 STAT4 PIK3R4 DES LIPE SNX32 UNC45B NCOA1 DMD DNAH9 VPS13B CUX1	1.34e-04	1074	167	17	C0006142
Disease	solanidine measurement	CYP2D7 CYP2D6	1.90e-04	4	167	2	EFO_0800966
Disease	Colorectal Carcinoma	MAP2 ABCA12 ABCA13 SYNE1 LAMA1 CASP8 APOB PROM1 GNAS DMD CTNND2 CUX1 ANAPC4	1.92e-04	702	167	13	C0009402
Disease	Headache, HbA1c measurement	CASP8 TKT ANAPC4	2.20e-04	21	167	3	EFO_0004541, HP_0002315
Disease	diastolic blood pressure, alcohol consumption measurement	ARHGAP42 HECTD4 SIPA1 ULK4	2.51e-04	54	167	4	EFO_0006336, EFO_0007878
Disease	quality of life during menstruation measurement, eating behaviour	CEP112 CTNND2	3.15e-04	5	167	2	EFO_0007829, EFO_0009366
Disease	Epidermolysis Bullosa Simplex	EXPH5 DST	3.15e-04	5	167	2	C0079298
Disease	Behcet Syndrome	ERAP1 APOB STAT4	3.30e-04	24	167	3	C0004943
Disease	unipolar depression, response to selective serotonin reuptake inhibitor	CYP2D7 CYP2D6 CUX1	3.30e-04	24	167	3	EFO_0003761, EFO_0005658
Disease	Major Depressive Disorder	CYP2D6 MAP2 TLR7 CMYA5 PROM1 CTNND2 CUX1	4.88e-04	243	167	7	C1269683
Disease	amino acid measurement	GALM ABCA12 COG7 SYNE1 MCM9 ULK4 PRKDC C5 MTUS2 PLXNA2 PMFBP1 GABRA2	5.08e-04	678	167	12	EFO_0005134
Disease	Alzheimer disease, polygenic risk score	LRRK2 ZZEF1 PPP2R3A DST ASCC2 ULK4 RAPGEF2 PLCH1 DIRAS2 FRMD5 MTSS2	5.36e-04	586	167	11	EFO_0030082, MONDO_0004975
Disease	mean arterial pressure	ARHGAP42 SH3TC2 ERAP1 RGL3 HECTD4 ARHGEF12 SIPA1 RPTOR GNAS MERTK	5.82e-04	499	167	10	EFO_0006340
Disease	epidermolysis bullosa simplex (is_implicated_in)	EXPH5 DST	6.56e-04	7	167	2	DOID:4644 (is_implicated_in)
Disease	Unipolar Depression	CYP2D6 MAP2 TLR7 CMYA5 PROM1 CTNND2 CUX1	7.12e-04	259	167	7	C0041696
Disease	mean platelet volume	ERAP1 LRRK2 FRYL RFX2 ARPC2 DOCK5 MCM9 A4GALT KIF28P TTC13 GNAS CATSPERG DDX39B CUX1 NIN	7.19e-04	1020	167	15	EFO_0004584
Disease	Retinitis pigmentosa	PDE6A PROM1 MERTK CNGB1	8.37e-04	74	167	4	cv:C0035334
Disease	coronary artery disease	ARHGAP42 TRPC4AP DNAH10 RGL3 HECTD4 ARHGEF12 APOB SIPA1 DOCK5 PPP2R3A ELFN1 RPTOR C5 MERTK RAPGEF2 PMFBP1	1.27e-03	1194	167	16	EFO_0001645
Disease	Short Stature, CTCAE	SLC10A7 IQSEC1	1.39e-03	10	167	2	C2919142
Disease	Short stature	SLC10A7 IQSEC1	1.39e-03	10	167	2	C0349588
Disease	3-phenylpropionate hydrocinnamate measurement	LAMA1 TTC6	1.39e-03	10	167	2	EFO_0021010
Disease	obesity (implicated_via_orthology)	KDM3A HK1 DNAH10 STAT4 ITPR1 NCOA1	1.45e-03	215	167	6	DOID:9970 (implicated_via_orthology)
Disease	response to antihypertensive drug	HECTD4 CEP112 RAPGEF2	1.62e-03	41	167	3	EFO_0005405
Disease	endometrial carcinoma, endometriosis	ARHGAP42 CEP112	1.69e-03	11	167	2	EFO_0001065, EFO_1001512
Disease	spleen volume	HECTD4 CASP8 ASCC2	1.86e-03	43	167	3	EFO_0600047
Disease	hypertension	ARHGAP42 TICRR ERAP1 RGL3 HECTD4 ARHGEF12 RPTOR	1.89e-03	307	167	7	EFO_0000537
Disease	ADHD symptom measurement	ARHGEF12 CUX1	2.02e-03	12	167	2	EFO_0007860
Disease	fructose measurement	TNIK UBR4	2.38e-03	13	167	2	EFO_0010477
Disease	male infertility (implicated_via_orthology)	TCTE1 PMFBP1	2.38e-03	13	167	2	DOID:12336 (implicated_via_orthology)
Disease	autoimmune hepatitis (is_implicated_in)	CYP2D6 STAT4	2.38e-03	13	167	2	DOID:2048 (is_implicated_in)
Disease	Charcot-Marie-Tooth disease type 4	SH3TC2 HK1	2.38e-03	13	167	2	cv:C4082197
Disease	reticulocyte count	ARHGAP42 HK1 DNAH10 VWA8 HECTD4 TKTL1 SIPA1 ADCY3 DOCK5 SLFN12L A4GALT ASCC2 DDX39B CUX1	2.56e-03	1045	167	14	EFO_0007986
Disease	reticulocyte measurement	ARHGAP42 HK1 DNAH10 VWA8 TUT7 HECTD4 TKTL1 SIPA1 ADCY3 DOCK5 SLFN12L ASCC2 DDX39B CUX1	2.74e-03	1053	167	14	EFO_0010700
Disease	Retinitis Pigmentosa	PDE6A PROM1 MERTK CNGB1	2.93e-03	104	167	4	C0035334
Disease	platelet crit	HK1 ERAP1 EXPH5 LRRK2 ARHGEF12 CASP8 TBC1D22B APOB NUP205 CBX6 CEP112 A4GALT CUX1	3.09e-03	952	167	13	EFO_0007985
Disease	Germ Cell Cancer	GDF3 TRIP13	3.19e-03	15	167	2	C0740345
Disease	Situs ambiguus	DNAH5 DNAH9	3.19e-03	15	167	2	C0266642
Disease	Embryonal Neoplasm	GDF3 TRIP13	3.19e-03	15	167	2	C0027654
Disease	Neoplasms, Germ Cell and Embryonal	GDF3 TRIP13	3.19e-03	15	167	2	C0027658
Disease	Germ cell tumor	GDF3 TRIP13	3.19e-03	15	167	2	C0205851
Disease	Neoplasms, Embryonal and Mixed	GDF3 TRIP13	3.19e-03	15	167	2	C0205852
Disease	Cancer, Embryonal	GDF3 TRIP13	3.19e-03	15	167	2	C0751364
Disease	Cancer, Embryonal and Mixed	GDF3 TRIP13	3.19e-03	15	167	2	C0751365
Disease	mental or behavioural disorder	VPS13C CMYA5 RFX2 DMD CTNND2	3.59e-03	179	167	5	EFO_0000677
Disease	platelet component distribution width	SH3TC2 SYNE1 LRRK2 ZZEF1 RFX2 ARPC2 DOCK5 A4GALT GNAS DEPDC7 CUX1	3.94e-03	755	167	11	EFO_0007984
Disease	phosphatidylcholine 40:6 measurement	RAPGEF2 DNAH9	4.10e-03	17	167	2	EFO_0010389
Disease	FEV/FEC ratio	ARHGAP42 MAP2 ZNF781 VPS13C TUT7 ADCY3 ITPR1 DES DST ASCC2 ULK4 CAPZA3 CCDC171 DNAH5 CUX1	4.31e-03	1228	167	15	EFO_0004713
Disease	lymphocyte measurement	HK1 SLFN12L IQSEC1 DDX39B	4.47e-03	117	167	4	EFO_0803546
Disease	sphingosine 1-phosphate measurement	ITPR1 DMD	4.59e-03	18	167	2	EFO_0800185
Disease	diastolic blood pressure, alcohol drinking	ARHGAP42 HECTD4 SIPA1 ULK4	4.61e-03	118	167	4	EFO_0004329, EFO_0006336
Disease	glycoprotein measurement	CASP8 APOB CEP112 MTSS2	4.75e-03	119	167	4	EFO_0004555
Disease	sugar consumption measurement	ABCA12 ELFN1 VPS13B PLXNA2	4.89e-03	120	167	4	EFO_0010158
Disease	Colorectal Neoplasms	ABCA12 ABCA13 SYNE1 LAMA1 CASP8 PROM1	5.07e-03	277	167	6	C0009404

Protein segments in the cluster

Peptide	Gene	Start	Entry
LQKIQTLLERAFSLN	TTC21B	306	Q7Z4L5
LALSFARLVEEQENK	CAPZA3	221	Q96KX2
LELAFEELFNINRKL	CEP295NL	341	Q96MC4
FLLLTLEQKNIAVET	C2orf49	26	Q9BVC5
LINRNSVLFSITLKD	CATSPERG	816	Q6ZRH7
KAQEEIRLTNLFTLT	ELFN1	361	P0C7U0
LAFDSVFLRIKQQLL	COG7	581	P83436
FILKANELLQVIDSS	ANAPC4	396	Q9UJX5
QKLALTQRLEDLEFD	BICD1	786	Q96G01
ENILDSRLIAAFEQK	CBX6	46	O95503
QSEIERIFELAKSLQ	CACNB3	251	P54284
RIFELAKSLQLVVLD	CACNB3	256	P54284
FREAVSKLELSLQEL	ABL2	1136	P42684
LDTDFIVLKNLRNLT	A4GALT	191	Q9NPC4
RKLFDLLDVLEFNQV	DDX39B	276	Q13838
NLFDVLRKANSVLLV	ABCA12	281	Q86UK0
LQIFSSLLQEKRFLR	ASCC2	351	Q9H1I8
VNNRIIEETLALKFE	ARPC2	6	O15144
TFELFKLEIRTLAQA	CCDC171	761	Q6TFL3
SNVELIAKNDLRFID	CEP44	61	Q9C0F1
FLQKRASILQEELTT	CEP112	936	Q8N8E3
FEILLALLNDSTKQV	ABCA13	1486	Q86UQ4
LELEKELCSLRFAIQ	ANKRD36	1426	A6QL64
LIQESLTFIDKQLAA	DMD	1381	P11532
EATQLLLKLLDFQNR	DEPDC7	341	Q96QD5
KSESFNRLLELVLLV	DIAPH2	826	O60879
ERSVQSDFLLIILKE	DHX29	706	Q7Z478
LILSNARLFLENLIK	DGAT1	96	O75907
ILASVKEQELQFERL	CTNND2	51	Q9UQB3
EELLFQSAIRLETNL	ATP10A	841	O60312
SELRKIFSNLEDILQ	ARHGEF12	826	Q9NZN5
LEENFEKLRLSLQDQ	MTUS2	1181	Q5JR59
KDFLDLLFQLELSRT	RASA4	321	O43374
LNIKESFTRLTELVL	RAB15	156	P59190
LIFANQTEEDILVRK	CYB5R2	181	Q6BCY4
RSFLENLKVNTENLL	PBLD	171	P30039
KDFLDLLFQLELSRT	RASA4B	321	C9J798
VKLRIDLLQAFSQLI	INTS7	621	Q9NVH2
KILNILDSIDFSQEI	NUP205	1181	Q92621
SIFDIATELNRLQKL	DBT	366	P11182
VLVLKQFLLQRDLNE	TENT4B	261	Q8NDF8
LLFTQKTDRQLLVLQ	PHLDB3	346	Q6NSJ2
NIDLDKFSLVLILFI	SLC10A7	226	Q0GE19
FLSKLNRELIETIQE	C20orf96	121	Q9NUD7
KTLLEFDLRLSDVAQ	TCTE1	446	Q5JU00
ARQLENELDLKLVSF	GOSR1	16	O95249
NLLRQLDFKVVSLLD	MALT1	371	Q9UDY8
TFSVLRLQLEKLLES	MERTK	846	Q12866
NADILIETKLVLSRF	ITPR1	661	Q14643
EALKNQLRQLETFEL	DST	3426	Q03001
ARQLLEKEFSNLISL	PPFIA3	1096	O75145
REIFLFNDLLVVTKI	IQSEC1	776	Q6DN90
LQTALEKTRTELFDL	CUX1	211	Q13948
KNNITIFTRILDRLL	GABRA2	36	P47869
FNLSAIKEREQLTLA	GDF3	111	Q9NR23
NKLLVSLDLLFAIRN	HMGXB3	811	Q12766
ETQFKAFLIRLLRDL	ERAP1	696	Q9NZ08
FAISILQQIELDLKA	EIF4A1	86	P60842
NKVFLLTFIRTLELQ	PLXNA2	1361	O75051
KLRQFTNALLESLIN	MTSS2	91	Q765P7
KTLLRDESLNIFQNL	PDE6A	636	P16499
LRVFLVIADSLQQKD	FRYL	451	O94915
LESNESLRVLKLFLN	LRRC74A	326	Q0VAA2
LALLTETIFLNQDLE	LRRK2	316	Q5S007
SFLNDEEARKILQVL	EXPH5	11	Q8NEV8
LSLREKFLQEVNSLI	HECTD4	1021	Q9Y4D8
VAEQLTLIDLELFSK	RGL3	251	Q3MIN7
FLSQIESDRLALLQV	HK1	786	P19367
RKSNFLQTLALLEEE	PPP2R3A	871	Q06190
LQALSLAVDKQFEER	TRIP13	411	Q15645
AQEVKLRFLEQLSIL	FCHSD1	11	Q86WN1
NVKELFQELLTLETR	DIRAS1	156	O95057
KFQLQSDLLRVDIIS	GALM	21	Q96C23
EEQVNKFVLSVLRLL	FRMD5	491	Q7Z6J6
KTTEVLRNLQDLLQF	APOB	4291	P04114
IKLTDSNFLRILENS	DNAH6	3101	Q9C0G6
LRLSLTDNQIVSKEF	KDM3A	156	Q9Y4C1
EVFALLVSSLLENLL	DOCK5	1191	Q9H7D0
LRFQKAFLTQLDELL	CYP2D6	241	P10635
LFQELLNLEKRRTVS	DIRAS2	161	Q96HU8
RLLKEIILVDDFSSN	GALNT8	211	Q9NY28
ESDFLLLVLKDIVSQ	DHX57	676	Q6P158
TALIKADNFLLENTL	C5	1166	P01031
EFLENLQEKSLRIEA	CMYA5	3551	Q8N3K9
LSIEDVTLKFLELQQ	DLGAP3	881	O95886
FLTTRTNEKVELQEL	DES	101	P17661
NIKFLARLDSQLEIL	FASTKD1	636	Q53R41
SAQELVKLLNELFAR	ADCY3	336	O60266
AEIFQLKSEILRLES	CCDC78	81	A2IDD5
ESNLSFLKELLFRIN	CASP8	56	Q14790
ISSINKRLLVLEAFQ	GSTZ1	186	O43708
RESLDDLTNLVVKLF	IDE	261	P14735
EIQTERANLTILFDK	DNAH9	2306	Q9NYC9
LFKDVLSLQLDFRNI	DRC3	41	Q9H069
LEDLSLFNNRISKID	DRC3	111	Q9H069
LLQLEVQSTFRKSLA	FAM186A	2326	A6NE01
EINEKFTELLLAITN	CYLD	91	Q9NQC7
LRSEIFKLLLAEFAQ	HPS6	666	Q86YV9
TSVVLLQELERFNKL	DNAH10	4231	Q8IVF4
FLLSALQVEEILKNL	IPO13	596	O94829
FLDRDLTKQSSINLV	KIF28P	241	B7ZC32
LVELSKLRQFSDVLD	DNAH5	3946	Q8TE73
FLTKLQELSIQRSAL	LIPE	206	Q05469
QFLTLIKSDDLNISR	KBTBD12	176	Q3ZCT8
SRFDLILVLLDTKNE	MCM9	481	Q9NXL9
RLQELQLEFTETQKL	PMFBP1	381	Q8TBY8
ILQLKTQLDDLETFA	RUNDC1	186	Q96C34
RRLFLVQDLVDSLKF	RTN1	691	Q16799
LRKDFVSEQLTSLLV	RARS1	166	P54136
IQDILSNFKLRAFLD	TAF5L	146	O75529
LEKFRQLLSSQNTDL	TBC1D22B	186	Q9NU19
DITLKIQFLRLLQSF	TRPC4AP	451	Q8TEL6
QVDDRDEFNLKLTLL	SYNE1	7526	Q8NF91
ALENNKELTAEVFRL	NIN	1276	Q8N4C6
ESVVQRLEQDFKLTL	RFX2	561	P48378
ISIAQSLKEFARLLI	ARHGAP42	81	A6NI28
RNDEKALLEQLVSFL	NCOA1	926	Q15788
RTISVILFLNKQDLL	GNAS	926	Q5JWF2
FKESQDLAIAIERLQ	LAMA1	1651	P25391
SELESLKVNLNIFLL	PROM1	596	O43490
LLTLDEQVLSFQRKV	SIPA1	321	Q96FS4
KQLSQNFLLDLRLTD	TFB1M	31	Q8WVM0
LRIFNKLTELQISLE	SH3TC2	1126	Q8TF17
LTEALLEQAEQLLKF	CCT8L1P	111	A6NM43
LRTFLSAELNLEQSK	SRGAP2B	291	P0DMP2
DLFQKLFRQDLLVAS	RPTOR	331	Q8N122
LSAFVLRLEVLLQKA	PNMA6A	256	P0CW24
TELIFALAKTNRLAE	CLTC	1171	Q00610
SVFDKQQFLILRLED	CHST15	466	Q7LFX5
SAIINDRLQELVKLF	CNGB1	561	Q14028
LRFQKAFLTQLDELL	CYP2D7	241	A0A087X1C5
ETALRFLELVQLKNL	PIK3R4	491	Q99570
NLFVFKELLTRLSEE	RAPGEF2	466	Q9Y4G8
SEAIFELKRCLLENI	URGCP	896	Q8TCY9
TDQTKELLARVFLAL	UNC45B	646	Q8IWX7
LFTSELLRQEQAKLN	TNIK	1001	Q9UKE5
KNAELALFELSRVIT	TTC13	196	Q8NBP0
NERLQEFVLVASKEL	USP19	1026	O94966
RTKAQILELLVLEQF	ZNF197	76	O14709
LLFQQLVSRLTAEEL	TICRR	376	Q7Z2Z1
LLSNEKIETAFLNAL	UBE3A	246	Q05086
LLLDATETVKLNTFL	TTC6	166	Q86TZ1
FLAEAELLNLRKISS	TKT	91	P29401
DFISDLDQLRKLLSF	PYGM	511	P11217
NFSTEKLLQRITEIL	SLFN12L	226	Q6IEE8
LNNNKLELLRDDTFL	SLITRK5	136	O94991
AESLFQLRRQLEKLE	STAT4	266	Q14765
NDFLQLITRLQKLLF	nan	151	Q6ZSR6
LTLFVARLNLQTKED	SNRNP35	51	Q16560
DLEKTLDVFNIILAR	VPS13C	431	Q709C8
SLERFRSLQDKLQLL	VIPAS39	171	Q9H9C1
VVERTLLEQFADKNL	USP28	841	Q96RU2
FSIRKENLTELANIE	TLR7	161	Q9NYK1
ALTEQLRKLVSFDQE	PLCH1	1541	Q4KWH8
FLRKVLQNALLLSDS	SNX10	101	Q9Y5X0
DKLLFRSDTLQITDL	MAP2	1246	P11137
KIAALENELTFLRSQ	MTFR2	141	Q6P444
NIRLFLAKLVINTEE	PRKDC	2141	P78527
LSKNILAFRDQNILL	PRKDC	3316	P78527
KASAELLRLTLDNIF	VPS13B	3406	Q7Z7G8
IRATFLQTDLLKLLV	ZZEF1	2371	O43149
STKEQILDLLVLEQF	ZSCAN9	86	O15535
AITQALFLREKNLLV	WDR3	151	Q9UNX4
FNLADLVISIRVKEL	TUT7	566	Q5VYS8
ELQLSDEQLQKRSIF	VWA8	556	A3KMH1
EVNQLRTSFLKLAEL	SNX32	256	Q86XE0
IKLLTSLFQDLQVEA	UBR4	481	Q5T4S7
FLILIDIREFTLVKN	ZNF781	241	Q8N8C0
IRELKNLFVLSFLAN	SLC36A4	226	Q6YBV0
LSKQDIFIRVIDLFT	TKTL1	496	P51854
QFLLNDSREVKISIL	ZBTB26	61	Q9HCK0
LLTELIRENFRNSKL	ULK4	556	Q96C45
RDSVVLSLLKQLQEF	ZW10	101	O43264
REVLVESQLLLAEFK	VPS13D	946	Q5THJ4
KDFLSSLRLLQQEDI	ZNF776	171	Q68DI1
EQAIFSLELLKVRSL	MYO9A	1281	B2RTY4
NLEQFVTRFLLKETL	NECAB1	126	Q8N987