Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	aliphatic amine oxidase activity	AOC2 AOC3	1.02e-04	4	83	2	GO:0052595
GeneOntologyBiologicalProcess	positive regulation of transcription by RNA polymerase II	SUPT20HL1 BMPR2 OTX1 KMT2D OTX2 HIVEP2 ATF5 ASH1L TBXT IRF5 SUPT20HL2 CAMTA2 HIF3A ZNF229 RAD54L2 APP RFX7 PHIP TLX2	1.33e-06	1390	81	19	GO:0045944
GeneOntologyBiologicalProcess	gastrulation	SUPT20HL1 BMPR2 OTX2 TBXT SUPT20HL2 AXIN1 TLX2	2.00e-05	212	81	7	GO:0007369
GeneOntologyCellularComponent	chromatin	SUPT20HL1 NCOR1 OTX1 OTX2 ATF5 ERF UBR5 TLX3 ACTB ACTG1 TBXT IRF5 SUPT20HL2 CAMTA2 HIF3A RFX7 TLX2	5.95e-05	1480	83	17	GO:0000785
GeneOntologyCellularComponent	dense body	ACTB ACTG1	3.23e-04	7	83	2	GO:0097433
GeneOntologyCellularComponent	apical junction complex	ACTB ASH1L ACTG1 YBX3 CGNL1	4.18e-04	158	83	5	GO:0043296
GeneOntologyCellularComponent	histone acetyltransferase complex	SUPT20HL1 ACTB ACTG1 SUPT20HL2	5.37e-04	94	83	4	GO:0000123
GeneOntologyCellularComponent	protein acetyltransferase complex	SUPT20HL1 ACTB ACTG1 SUPT20HL2	7.86e-04	104	83	4	GO:0031248
GeneOntologyCellularComponent	acetyltransferase complex	SUPT20HL1 ACTB ACTG1 SUPT20HL2	9.37e-04	109	83	4	GO:1902493
HumanPheno	Short columella	KMT2D ERF ACTB ACTG1	1.58e-05	29	28	4	HP:0002000
MousePheno	abnormal allantois morphology	SUPT20HL1 OTX2 ERF UBR5 TBXT SUPT20HL2 AXIN1	1.03e-06	112	67	7	MP:0001726
MousePheno	abnormal mesoderm morphology	SUPT20HL1 BMPR2 OTX2 TBXT SUPT20HL2 AXIN1	3.17e-05	127	67	6	MP:0014141
MousePheno	abnormal rostral-caudal axis patterning	SUPT20HL1 BMPR2 OTX2 TBXT SUPT20HL2 AXIN1	3.94e-05	132	67	6	MP:0005221
MousePheno	abnormal germ layer development	SUPT20HL1 OTX2 TBXT SUPT20HL2 AXIN1 TLX2	6.41e-05	144	67	6	MP:0001674
MousePheno	abnormal placenta development	SUPT20HL1 ERF UBR5 ASH1L TBXT SUPT20HL2	1.15e-04	160	67	6	MP:0001712
MousePheno	abnormal germ layer morphology	SUPT20HL1 BMPR2 OTX2 TBXT SUPT20HL2 AXIN1	1.19e-04	161	67	6	MP:0014138
MousePheno	abnormal axial mesoderm morphology	OTX2 TBXT AXIN1	1.32e-04	21	67	3	MP:0001684
MousePheno	decreased susceptibility to colitis induced morbidity/mortality	TPSG1 MUC4	1.35e-04	4	67	2	MP:0013299
MousePheno	increased susceptibility to age-related hearing loss	PTPRQ ACTB ACTG1	1.74e-04	23	67	3	MP:0004748
MousePheno	decreased midbrain size	OTX1 OTX2 ERF	1.74e-04	23	67	3	MP:0012089
MousePheno	forebrain hypoplasia	OTX2 ERF AXIN1	1.98e-04	24	67	3	MP:0000784
MousePheno	midbrain hypoplasia	OTX2 ERF	2.24e-04	5	67	2	MP:0012090
MousePheno	short outer hair cell stereocilia	PTPRQ ACTB	2.24e-04	5	67	2	MP:0004531
MousePheno	abnormal outer hair cell stereocilia length	PTPRQ ACTB	2.24e-04	5	67	2	MP:0014411
MousePheno	embryonic growth retardation	SUPT20HL1 BMPR2 OTX2 ERF UBR5 ACTB ACTG1 TBXT SUPT20HL2 RAD54L2 REXO1 AXIN1	2.40e-04	763	67	12	MP:0003984
MousePheno	decreased cochlear hair cell stereocilia number	PTPRQ ACTB ACTG1	2.53e-04	26	67	3	MP:0004523
MousePheno	decreased interferon-alpha secretion	TRIM65 IRF5 UNC93B1	2.83e-04	27	67	3	MP:0008563
MousePheno	failure of chorioallantoic fusion	SUPT20HL1 ERF UBR5 SUPT20HL2	2.94e-04	67	67	4	MP:0009657
MousePheno	abnormal primitive streak morphology	SUPT20HL1 BMPR2 OTX2 TBXT SUPT20HL2 TLX2	3.95e-04	201	67	6	MP:0002231
MousePheno	abnormal placenta physiology	SUPT20HL1 ERF UBR5 ASH1L TBXT SUPT20HL2	4.27e-04	204	67	6	MP:0010038
MousePheno	abnormal midbrain size	OTX1 OTX2 ERF	4.30e-04	31	67	3	MP:0012088
MousePheno	abnormal interferon-alpha secretion	TRIM65 IRF5 UNC93B1	4.30e-04	31	67	3	MP:0008557
MousePheno	abnormal neural tube closure	SUPT20HL1 OTX2 ERF ZNRF3 ACTG1 TBXT SUPT20HL2 AXIN1	4.30e-04	378	67	8	MP:0003720
MousePheno	abnormal mesoderm development	SUPT20HL1 OTX2 TBXT SUPT20HL2	4.31e-04	74	67	4	MP:0001680
MousePheno	split notochord	TBXT AXIN1	4.68e-04	7	67	2	MP:0004713
MousePheno	abnormal trigeminal V mesencephalic nucleus morphology	OTX1 OTX2	4.68e-04	7	67	2	MP:0000906
MousePheno	abnormal B-1b B cell morphology	RASGRP1 SIGLEC10 BLNK	6.17e-04	35	67	3	MP:0008165
MousePheno	abnormal left-right axis symmetry of the somites	SUPT20HL1 SUPT20HL2	6.22e-04	8	67	2	MP:0005224
MousePheno	abnormal orbitosphenoid bone morphology	OTX1 OTX2	6.22e-04	8	67	2	MP:0004457
MousePheno	abnormal embryonic tissue morphology	SUPT20HL1 BMPR2 OTX2 ERF ZNRF3 UBR5 RBBP8 ACTG1 TBXT SUPT20HL2 RAD54L2 REXO1 AXIN1 TLX2	6.99e-04	1116	67	14	MP:0002085
MousePheno	open neural tube	SUPT20HL1 OTX2 ERF ACTG1 TBXT SUPT20HL2	7.33e-04	226	67	6	MP:0000929
MousePheno	prenatal growth retardation	SUPT20HL1 BMPR2 OTX2 ERF UBR5 ACTB ACTG1 TBXT SUPT20HL2 RAD54L2 REXO1 AXIN1	7.76e-04	869	67	12	MP:0010865
MousePheno	abnormal susceptibility to hearing loss	PTPRQ ACTB ACTG1	7.87e-04	38	67	3	MP:0006334
MousePheno	spina bifida	SUPT20HL1 ACTG1 TBXT SUPT20HL2	7.96e-04	87	67	4	MP:0003054
MousePheno	decreased circulating interleukin-12b level	IRF5 UNC93B1	7.97e-04	9	67	2	MP:0008648
MousePheno	decreased inferior colliculus size	OTX1 OTX2	7.97e-04	9	67	2	MP:0009038
MousePheno	abnormal chorioallantoic fusion	SUPT20HL1 ERF UBR5 SUPT20HL2	9.04e-04	90	67	4	MP:0002824
Domain	Otx_TF	OTX1 OTX2	1.81e-05	2	80	2	IPR003025
Domain	-	AOC2 AOC3	5.42e-05	3	80	2	2.70.98.20
Domain	Otx_TF_C	OTX1 OTX2	5.42e-05	3	80	2	IPR013851
Domain	Cu_amine_oxidase_N3	AOC2 AOC3	5.42e-05	3	80	2	IPR015802
Domain	Cu_amine_oxidase_N2	AOC2 AOC3	5.42e-05	3	80	2	IPR015800
Domain	Cu_amine_oxidN2	AOC2 AOC3	5.42e-05	3	80	2	PF02727
Domain	Cu_amine_oxidN3	AOC2 AOC3	5.42e-05	3	80	2	PF02728
Domain	Cu_amine_oxidase_N-reg	AOC2 AOC3	5.42e-05	3	80	2	IPR016182
Domain	Cu_amine_oxid	AOC2 AOC3	5.42e-05	3	80	2	PF01179
Domain	TF_Otx	OTX1 OTX2	5.42e-05	3	80	2	PF03529
Domain	Cu_amine_oxidase_C	AOC2 AOC3	5.42e-05	3	80	2	IPR015798
Domain	COPPER_AMINE_OXID_1	AOC2 AOC3	5.42e-05	3	80	2	PS01164
Domain	COPPER_AMINE_OXID_2	AOC2 AOC3	5.42e-05	3	80	2	PS01165
Domain	Cu_amine_oxidase	AOC2 AOC3	1.08e-04	4	80	2	IPR000269
Domain	ACTINS_1	ACTB ACTG1	4.99e-04	8	80	2	PS00406
Domain	IQ_motif_EF-hand-BS	RASGRF2 IQSEC2 MYO1F CAMTA2	6.03e-04	90	80	4	IPR000048
Domain	IQ	RASGRF2 IQSEC2 MYO1F CAMTA2	6.82e-04	93	80	4	PS50096
Domain	Post-SET_dom	KMT2D ASH1L	2.09e-03	16	80	2	IPR003616
Domain	PostSET	KMT2D ASH1L	2.09e-03	16	80	2	SM00508
Domain	Actin_CS	ACTB ACTG1	2.09e-03	16	80	2	IPR004001
Domain	POST_SET	KMT2D ASH1L	2.09e-03	16	80	2	PS50868
Domain	ACTINS_2	ACTB ACTG1	2.36e-03	17	80	2	PS00432
Domain	Actin/actin-like_CS	ACTB ACTG1	2.65e-03	18	80	2	IPR020902
Domain	ACTINS_ACT_LIKE	ACTB ACTG1	2.96e-03	19	80	2	PS01132
Domain	RasGEFN	RASGRP1 RASGRF2	3.27e-03	20	80	2	SM00229
Domain	IQ	IQSEC2 MYO1F CAMTA2	3.51e-03	71	80	3	PF00612
Domain	RasGEF_N	RASGRP1 RASGRF2	3.61e-03	21	80	2	PF00618
Domain	Ras-like_Gua-exchang_fac_N	RASGRP1 RASGRF2	3.96e-03	22	80	2	IPR000651
Domain	-	FBXO24 UBR5	3.96e-03	22	80	2	2.130.10.30
Domain	RASGEF_NTER	RASGRP1 RASGRF2	3.96e-03	22	80	2	PS50212
Domain	RCC1/BLIP-II	FBXO24 UBR5	4.32e-03	23	80	2	IPR009091
Domain	IQ	RASGRF2 MYO1F CAMTA2	5.08e-03	81	80	3	SM00015
Domain	RASGEF	RASGRP1 RASGRF2	5.51e-03	26	80	2	PS00720
Domain	RASGEF_CAT	RASGRP1 RASGRF2	6.82e-03	29	80	2	PS50009
Domain	RasGEF	RASGRP1 RASGRF2	7.29e-03	30	80	2	PF00617
Domain	-	RASGRP1 RASGRF2	7.29e-03	30	80	2	1.10.840.10
Domain	Ras_GEF_dom	RASGRP1 RASGRF2	7.29e-03	30	80	2	IPR023578
Domain	RASGEF_cat_dom	RASGRP1 RASGRF2	7.29e-03	30	80	2	IPR001895
Domain	RasGEF	RASGRP1 RASGRF2	7.29e-03	30	80	2	SM00147
Domain	-	NCOR1 OTX1 OTX2 TLX3 TLX2	7.36e-03	283	80	5	1.10.10.60
Domain	Actin	ACTB ACTG1	7.77e-03	31	80	2	IPR004000
Domain	Actin	ACTB ACTG1	7.77e-03	31	80	2	PF00022
Domain	ACTIN	ACTB ACTG1	7.77e-03	31	80	2	SM00268
Domain	Homeobox_CS	OTX1 OTX2 TLX3 TLX2	8.37e-03	186	80	4	IPR017970
Pathway	REACTOME_INTERACTION_BETWEEN_L1_AND_ANKYRINS	SPTBN5 ACTB ACTG1	8.61e-06	10	60	3	MM15112
Pubmed	A census of human transcription factors: function, expression and evolution.	OTX1 KMT2D OTX2 HIVEP2 ATF5 ERF TLX3 ASH1L TBXT IRF5 YBX3 CAMTA2 HIF3A RFX7 TLX2	3.71e-09	908	83	15	19274049
Pubmed	Cripto is required for mesoderm and endoderm cell allocation during mouse gastrulation.	SUPT20HL1 OTX2 TBXT SUPT20HL2	1.75e-07	21	83	4	23747598
Pubmed	Multiple epigenetic maintenance factors implicated by the loss of Mll2 in mouse development.	KMT2D OTX2 TBXT	4.56e-07	7	83	3	16540515
Pubmed	Actin, troponin C, Alzheimer amyloid precursor protein and pro-interleukin 1 beta as substrates of the protease from human immunodeficiency virus.	ACTB ACTG1 APP	1.55e-06	10	83	3	1907279
Pubmed	Interaction network of human early embryonic transcription factors.	NCOR1 KMT2D OTX2 HIVEP2 ERF RAD54L2 APP RFX7	2.03e-06	351	83	8	38297188
Pubmed	The role of microtubule actin cross-linking factor 1 (MACF1) in the Wnt signaling pathway.	OTX2 TBXT AXIN1	2.13e-06	11	83	3	16815997
Pubmed	Forebrain and midbrain regions are deleted in Otx2-/- mutants due to a defective anterior neuroectoderm specification during gastrulation.	OTX1 OTX2 TBXT	2.84e-06	12	83	3	7588062
Pubmed	High-throughput screen for genes predominantly expressed in the ICM of mouse blastocysts by whole mount in situ hybridization.	OTX2 ACTB TBXT YBX3 GPANK1	3.18e-06	94	83	5	16325481
Pubmed	A QUICK screen for Lrrk2 interaction partners--leucine-rich repeat kinase 2 is involved in actin cytoskeleton dynamics.	LIMA1 ACTB MYO1F ACTG1	3.47e-06	43	83	4	20876399
Pubmed	Network-based prediction of protein interactions.	OTX1 ACTB KHDRBS2 ACTG1	3.81e-06	44	83	4	30886144
Pubmed	Visceral endoderm-restricted translation of Otx1 mediates recovery of Otx2 requirements for specification of anterior neural plate and normal gastrulation.	OTX1 OTX2 TBXT	4.68e-06	14	83	3	9811592
Pubmed	Ecsit is required for Bmp signaling and mesoderm formation during mouse embryogenesis.	OTX2 TBXT TLX2	4.68e-06	14	83	3	14633973
Pubmed	Beta- and gamma-cytoplasmic actins are required for meiosis in mouse oocytes.	ACTB ACTG1	5.63e-06	2	83	2	21778137
Pubmed	De novo mutations in the actin genes ACTB and ACTG1 cause Baraitser-Winter syndrome.	ACTB ACTG1	5.63e-06	2	83	2	22366783
Pubmed	Differential transcriptional control as the major molecular event in generating Otx1-/- and Otx2-/- divergent phenotypes.	OTX1 OTX2	5.63e-06	2	83	2	10068635
Pubmed	Prenatal presentation and diagnosis of Baraitser-Winter syndrome using exome sequencing.	ACTB ACTG1	5.63e-06	2	83	2	32588558
Pubmed	Linkage Relations of the Genes Histocompatibility-2 and Fused Tail, Brachyury and Kinky Tail in the Mouse, as Determined by Tumor Transplantation.	TBXT AXIN1	5.63e-06	2	83	2	17247577
Pubmed	Baraitser-Winter cerebrofrontofacial syndrome.	ACTB ACTG1	5.63e-06	2	83	2	27625340
Pubmed	From fly head to mammalian forebrain: the story of otd and Otx.	OTX1 OTX2	5.63e-06	2	83	2	7974744
Pubmed	Differentiation of cerebellar cell identities in absence of Fgf signalling in zebrafish Otx morphants.	OTX1 OTX2	5.63e-06	2	83	2	16611693
Pubmed	Human Siglec-10 can bind to vascular adhesion protein-1 and serves as its substrate.	SIGLEC10 AOC3	5.63e-06	2	83	2	19861682
Pubmed	Isolation of cDNA clones for mouse cytoskeletal gamma-actin and differential expression of cytoskeletal actin mRNAs in mouse cells.	ACTB ACTG1	5.63e-06	2	83	2	3221869
Pubmed	Otx genes in corticogenesis and brain development.	OTX1 OTX2	5.63e-06	2	83	2	10498271
Pubmed	Otx2 expression in anterior neuroectoderm and forebrain/midbrain is directed by more than six enhancers.	OTX1 OTX2	5.63e-06	2	83	2	24457099
Pubmed	Measurements of spatiotemporal changes in G-actin concentration reveal its effect on stimulus-induced actin assembly and lamellipodium extension.	ACTB ACTG1	5.63e-06	2	83	2	21502360
Pubmed	The evolution and complexity of the genes encoding the cytoskeletal proteins of human epidermal cells.	ACTB ACTG1	5.63e-06	2	83	2	6686106
Pubmed	Developmental rescue of Drosophila cephalic defects by the human Otx genes.	OTX1 OTX2	5.63e-06	2	83	2	9520436
Pubmed	Actin amino-acid sequences. Comparison of actins from calf thymus, bovine brain, and SV40-transformed mouse 3T3 cells with rabbit skeletal muscle actin.	ACTB ACTG1	5.63e-06	2	83	2	213279
Pubmed	The First Korean Case of Baraitser-Winter Cerebro-Fronto-Facial Syndrome with a Novel Mutation in ACTB Diagnosed Via Targeted Gene Panel Sequencing and Literature Review.	ACTB ACTG1	5.63e-06	2	83	2	33334799
Pubmed	β-Actin specifically controls cell growth, migration, and the G-actin pool.	ACTB ACTG1	5.63e-06	2	83	2	21900491
Pubmed	Beta and gamma-cytoplasmic actins display distinct distribution and functional diversity.	ACTB ACTG1	5.63e-06	2	83	2	19638415
Pubmed	Otx genes and the genetic control of brain morphogenesis.	OTX1 OTX2	5.63e-06	2	83	2	10049527
Pubmed	Otx2 controls identity and fate of glutamatergic progenitors of the thalamus by repressing GABAergic differentiation.	OTX1 OTX2	5.63e-06	2	83	2	16738237
Pubmed	Botulinum C2 toxin ADP-ribosylates cytoplasmic beta/gamma-actin in arginine 177.	ACTB ACTG1	5.63e-06	2	83	2	3335520
Pubmed	Association of human immunodeficiency virus Nef protein with actin is myristoylation dependent and influences its subcellular localization.	ACTB ACTG1	5.63e-06	2	83	2	9288906
Pubmed	High level expression of transfected beta- and gamma-actin genes differentially impacts on myoblast cytoarchitecture.	ACTB ACTG1	5.63e-06	2	83	2	1577857
Pubmed	Function and evolution of Otx proteins.	OTX1 OTX2	5.63e-06	2	83	2	10375352
Pubmed	Activity-dependent oligodendrocyte calcium dynamics and their changes in Alzheimer's disease.	ACTB APP	5.63e-06	2	83	2	38026691
Pubmed	Baraitser-Winter Cerebrofrontofacial Syndrome	ACTB ACTG1	5.63e-06	2	83	2	26583190
Pubmed	Knockout of ACTB and ACTG1 with CRISPR/Cas9(D10A) Technique Shows that Non-Muscle β and γ Actin Are Not Equal in Relation to Human Melanoma Cells' Motility and Focal Adhesion Formation.	ACTB ACTG1	5.63e-06	2	83	2	32326615
Pubmed	Otx1 and Otx2 in the development and evolution of the mammalian brain.	OTX1 OTX2	5.63e-06	2	83	2	9843484
Pubmed	Severe forms of Baraitser-Winter syndrome are caused by ACTB mutations rather than ACTG1 mutations.	ACTB ACTG1	5.63e-06	2	83	2	23756437
Pubmed	Gene and domain duplication in the chordate Otx gene family: insights from amphioxus Otx.	OTX1 OTX2	5.63e-06	2	83	2	9580990
Pubmed	Otx1 and Otx2 define layers and regions in developing cerebral cortex and cerebellum.	OTX1 OTX2	5.63e-06	2	83	2	7931541
Pubmed	Structural evolution of Otx genes in craniates.	OTX1 OTX2	5.63e-06	2	83	2	11504847
Pubmed	Targeting UBR5 in hepatocellular carcinoma cells and precise treatment via echinacoside nanodelivery.	UBR5 AXIN1	5.63e-06	2	83	2	36224534
Pubmed	Cytochalasin D-induced actin gene expression in murine erythroleukemia cells.	ACTB ACTG1	5.63e-06	2	83	2	8482333
Pubmed	The unique substrate specificity of human AOC2, a semicarbazide-sensitive amine oxidase.	AOC2 AOC3	5.63e-06	2	83	2	19588076
Pubmed	Impaired muscle relaxation and mitochondrial fission associated with genetic ablation of cytoplasmic actin isoforms.	ACTB ACTG1	5.63e-06	2	83	2	29265728
Pubmed	Multi-isotope imaging mass spectrometry reveals slow protein turnover in hair-cell stereocilia.	ACTB ACTG1	5.63e-06	2	83	2	22246323
Pubmed	Expression of the homeobox genes OTX2 and OTX1 in the early developing human brain.	OTX1 OTX2	5.63e-06	2	83	2	20354145
Pubmed	Evolution and homology of the nervous system: cross-phylum rescues of otd/Otx genes.	OTX1 OTX2	5.63e-06	2	83	2	9635399
Pubmed	Structure, chromosome location, and expression of the human gamma-actin gene: differential evolution, location, and expression of the cytoskeletal beta- and gamma-actin genes.	ACTB ACTG1	5.63e-06	2	83	2	2837653
Pubmed	Prevalence of Cytoplasmic Actin Mutations in Diffuse Large B-Cell Lymphoma and Multiple Myeloma: A Functional Assessment Based on Actin Three-Dimensional Structures.	ACTB ACTG1	5.63e-06	2	83	2	32349449
Pubmed	Baraitser-Winter cerebrofrontofacial syndrome: Report of two adult siblings.	ACTB ACTG1	5.63e-06	2	83	2	32506774
Pubmed	Anatomical distribution of primary amine oxidase activity in four adipose depots and plasma of severely obese women with or without a dysmetabolic profile.	AOC2 AOC3	5.63e-06	2	83	2	27766585
Pubmed	Differential arginylation of actin isoforms is regulated by coding sequence-dependent degradation.	ACTB ACTG1	5.63e-06	2	83	2	20847274
Pubmed	Thin fur, a recessive mutant on chromosome 17 of the mouse.	TBXT AXIN1	5.63e-06	2	83	2	5031320
Pubmed	OTX1 and OTX2 as possible molecular markers of sinonasal carcinomas and olfactory neuroblastomas.	OTX1 OTX2	5.63e-06	2	83	2	28348423
Pubmed	Genetic and molecular roles of Otx homeodomain proteins in head development.	OTX1 OTX2	5.63e-06	2	83	2	10767524
Pubmed	OTX1 and OTX2 Genes in Medulloblastoma.	OTX1 OTX2	5.63e-06	2	83	2	30797919
Pubmed	A genome-wide screen to identify transcription factors expressed in pelvic Ganglia of the lower urinary tract.	OTX1 OTX2 HIVEP2 ATF5 ERF GTF3C1 TBXT IRF5 HIF3A PHIP	7.42e-06	709	83	10	22988430
Pubmed	Functional equivalency between Otx2 and Otx1 in development of the rostral head.	OTX1 OTX2 TBXT	1.24e-05	19	83	3	9895322
Pubmed	Molecular characterization of abLIM, a novel actin-binding and double zinc finger protein.	ACTB ACTG1	1.69e-05	3	83	2	9245787
Pubmed	Decreased UDP-GlcNAc levels abrogate proliferation control in EMeg32-deficient cells.	OTX2 TBXT	1.69e-05	3	83	2	11013212
Pubmed	Impact of altered actin gene expression on vinculin, talin, cell spreading, and motility.	ACTB ACTG1	1.69e-05	3	83	2	7646816
Pubmed	TRIM65 triggers β-catenin signaling via ubiquitylation of Axin1 to promote hepatocellular carcinoma.	TRIM65 AXIN1	1.69e-05	3	83	2	28754688
Pubmed	Otx5 regulates genes that show circadian expression in the zebrafish pineal complex.	OTX1 OTX2	1.69e-05	3	83	2	11753388
Pubmed	Angiostatin and plasminogen share binding to endothelial cell surface actin.	ACTB ACTG1	1.69e-05	3	83	2	15746964
Pubmed	Expression of the homeobox genes PAX6, OTX2, and OTX1 in the early human fetal retina.	OTX1 OTX2	1.69e-05	3	83	2	19414065
Pubmed	Actin Is Crucial for All Kinetically Distinguishable Forms of Endocytosis at Synapses.	ACTB ACTG1	1.69e-05	3	83	2	27840001
Pubmed	Otx1 function overlaps with Otx2 in development of mouse forebrain and midbrain.	OTX1 OTX2	1.69e-05	3	83	2	9077465
Pubmed	Epithelial Protein Lost in Neoplasm alpha (Eplin-alpha) is transcriptionally regulated by G-actin and MAL/MRTF coactivators.	LIMA1 ACTG1	1.69e-05	3	83	2	20236507
Pubmed	The TINS Lecture. Understanding the roles of Otx1 and Otx2 in the control of brain morphogenesis.	OTX1 OTX2	1.69e-05	3	83	2	10199636
Pubmed	Restricted morphological and behavioral abnormalities following ablation of β-actin in the brain.	ACTB ACTG1	1.69e-05	3	83	2	22403730
Pubmed	BEST1 expression in the retinal pigment epithelium is modulated by OTX family members.	OTX1 OTX2	1.69e-05	3	83	2	18849347
Pubmed	CRX is a diagnostic marker of retinal and pineal lineage tumors.	OTX1 OTX2	1.69e-05	3	83	2	19936203
Pubmed	Generation of bicistronic reporter knockin mice for visualizing germ layers.	OTX2 TBXT	1.69e-05	3	83	2	31189761
Pubmed	Characterization of AOC2 gene encoding a copper-binding amine oxidase expressed specifically in retina.	AOC2 AOC3	1.69e-05	3	83	2	14585497
Pubmed	Mutation analysis of the short cytoplasmic domain of the cell-cell adhesion molecule CEACAM1 identifies residues that orchestrate actin binding and lumen formation.	ACTB ACTG1	1.69e-05	3	83	2	17192268
Pubmed	Aberrant NMDA receptor DNA methylation detected by epigenome-wide analysis of hippocampus and prefrontal cortex in major depression.	OTX2 MUC4	1.69e-05	3	83	2	25571874
Pubmed	Molecular basis for G-actin binding to RPEL motifs from the serum response factor coactivator MAL.	ACTB ACTG1	1.69e-05	3	83	2	19008859
Pubmed	Interaction of Receptor-Binding Domain of the SARS-CoV-2 Omicron Variant with hACE2 and Actin.	ACTB ACTG1	1.69e-05	3	83	2	39195208
Pubmed	Functional molecular complexes of human N-formyl chemoattractant receptors and actin.	ACTB ACTG1	1.69e-05	3	83	2	8228254
Pubmed	The APP intracellular domain (AICD) inhibits Wnt signalling and promotes neurite outgrowth.	APP AXIN1	1.69e-05	3	83	2	22613765
Pubmed	A new recurrent and specific cryptic translocation, t(5;14)(q35;q32), is associated with expression of the Hox11L2 gene in T acute lymphoblastic leukemia.	TLX3 TLX2	1.69e-05	3	83	2	11587205
Pubmed	Identification, tissue expression, and functional characterization of Otx3, a novel member of the Otx family.	OTX1 OTX2	1.69e-05	3	83	2	12055180
Pubmed	CTGF/Hcs24 interacts with the cytoskeletal protein actin in chondrocytes.	ACTB ACTG1	1.69e-05	3	83	2	12470643
Pubmed	Isolation and characterization of full-length cDNA clones for human alpha-, beta-, and gamma-actin mRNAs: skeletal but not cytoplasmic actins have an amino-terminal cysteine that is subsequently removed.	ACTB ACTG1	1.69e-05	3	83	2	6865942
Pubmed	The p38-interacting protein (p38IP) regulates G2/M progression by promoting α-tubulin acetylation via inhibiting ubiquitination-induced degradation of the acetyltransferase GCN5.	SUPT20HL1 SUPT20HL2	1.69e-05	3	83	2	24220028
Pubmed	Development expression of Hox11 and specification of splenic cell fate.	TLX3 TLX2	1.69e-05	3	83	2	7747804
Pubmed	Putative tumor suppressor EDD interacts with and up-regulates APC.	UBR5 AXIN1	1.69e-05	3	83	2	18076571
Pubmed	Derivation of mutant t-haplotypes of the mouse by presumed duplication or deletion.	TBXT AXIN1	1.69e-05	3	83	2	924142
Pubmed	Supt20 is required for development of the axial skeleton.	SUPT20HL1 TBXT SUPT20HL2	1.69e-05	21	83	3	27894818
Pubmed	p38 and a p38-interacting protein are critical for downregulation of E-cadherin during mouse gastrulation.	SUPT20HL1 TBXT SUPT20HL2	1.95e-05	22	83	3	16751104
Pubmed	Otx2 is required to respond to signals from anterior neural ridge for forebrain specification.	OTX1 OTX2 TBXT	2.56e-05	24	83	3	11820816
Pubmed	Transcriptional regulatory networks in epiblast cells and during anterior neural plate development as modeled in epiblast stem cells.	OTX1 OTX2 TBXT	3.27e-05	26	83	3	22992956
Pubmed	Emx and Otx homeobox genes in the developing mouse brain.	OTX1 OTX2	3.37e-05	4	83	2	7901323
Pubmed	Functional analyses of placental protein 13/galectin-13.	ACTB ACTG1	3.37e-05	4	83	2	15009185
Pubmed	The formin-homology-domain-containing protein FHOD1 enhances cell migration.	ACTB ACTG1	3.37e-05	4	83	2	12665555
Interaction	LSP1 interactions	LIMA1 BMPR2 FAM120B ACTB ACTG1	7.90e-07	43	81	5	int:LSP1
Interaction	ARPC1B interactions	LIMA1 UBR5 ACTB ASH1L ACTG1 YBX3 CGNL1 APP	2.43e-06	215	81	8	int:ARPC1B
Interaction	TLE3 interactions	NCOR1 KMT2D HIVEP2 UBR5 RBBP8 TLX3 TBXT RAD54L2 APP TLX2	2.62e-06	376	81	10	int:TLE3
Interaction	PLAAT1 interactions	TLX3 APP GPANK1	1.01e-05	11	81	3	int:PLAAT1
Interaction	ATXN1L interactions	NCOR1 ZSWIM8 TLX3 TBXT RAD54L2 TLX2	3.15e-05	150	81	6	int:ATXN1L
Interaction	TLE4 interactions	OTX1 OTX2 TLX3 TBXT TLX2	3.46e-05	92	81	5	int:TLE4
Interaction	LGALS13 interactions	OTX1 ACTB ACTG1	4.08e-05	17	81	3	int:LGALS13
Interaction	RNASE11 interactions	OTX2 APP	4.77e-05	3	81	2	int:RNASE11
Cytoband	Ensembl 112 genes in cytogenetic band chr19q13	CA11 ATF5 ERF NUMBL JOSD2 SIGLEC10 ACP4 HIF3A ZNF229	3.06e-04	1192	83	9	chr19q13
Cytoband	16q24	VPS9D1 ZNF469	4.32e-04	17	83	2	16q24
Cytoband	19q13.3	CA11 ATF5 SIGLEC10	4.55e-04	82	83	3	19q13.3
Cytoband	Xp22.11	SUPT20HL1 SUPT20HL2	6.63e-04	21	83	2	Xp22.11
Cytoband	15q21.3	CGNL1 RFX7	1.85e-03	35	83	2	15q21.3
GeneFamily	Actins	ACTB ACTG1	1.61e-04	6	60	2	929
ToppCell	droplet-Marrow-nan-21m-Myeloid\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ACTB MYO1F ACTG1 IRF5 UNC93B1 APP	1.28e-06	187	82	6	20b25b0d08550a1e8e997c5ce67d8e34bf7fc398
ToppCell	facs-Marrow-B-cells-18m-Lymphocytic-immature_B_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	RASGRP1 ACTB BLNK DCBLD1 IRF5 UNC93B1	1.45e-06	191	82	6	10644258b97f9c99eb0e199b64b970f6b986aa41
ToppCell	facs-Marrow-B-cells-18m-Lymphocytic-immature_B_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	RASGRP1 ACTB BLNK DCBLD1 IRF5 UNC93B1	1.45e-06	191	82	6	408942fc8db939239aeee6ae07a21362133c9e2e
ToppCell	facs-Trachea-3m-Mesenchymal-myofibroblast-tracheobronchial_smooth_muscle_cell-smooth_muscle_cell_of_trachea_l44-58\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	NT5C1A FAT3 PTPRQ COX6A2 COL22A1	1.44e-05	167	82	5	d78356bf0c473816dbabaee51984940bd822f84e
ToppCell	facs-Diaphragm-Limb_Muscle-24m\|Diaphragm / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	HIVEP2 ERF FAT3 RP1 COL22A1	1.52e-05	169	82	5	12bdc709bc000d7f9061ecd9fbd57233eaacb7e2
ToppCell	Immune_cells-Dendritic_cells\|World / Lineage and Cell class	TMEM221 COX6A2 BLNK IRF5 UNC93B1	1.57e-05	170	82	5	094dc211d80c89ecb1010855f1fe6eeb71bf0e20
ToppCell	Fetal_brain-organoid_Tanaka_cellReport-GW13-Mesenchymal\|GW13 / Sample Type, Dataset, Time_group, and Cell type.	PCED1B MYO1F RFX7 AXIN1	1.85e-05	85	82	4	3f33e897eb030043905a6a1a83377cd601652958
ToppCell	facs-Trachea-24m-Hematologic\|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	ACTB MYO1F BLNK IRF5 UNC93B1	2.17e-05	182	82	5	a6162498a8a41a7fdf84d744e4203f99dfb284fa
ToppCell	droplet-Marrow-nan-21m-Myeloid-nan\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ACTB MYO1F ACTG1 UNC93B1 APP	2.29e-05	184	82	5	d071f53ad9e957dc0f8ae9c53aaa31cfebcf815e
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell-Degenerative_Outer_Medullary_Collecting_Duct_Principal_Cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	RASGRP1 ACTB BLNK ACTG1 COL22A1	2.74e-05	191	82	5	0a0719a0a49ae0099d61e22585ac74c10c24b4a2
ToppCell	facs-Marrow-B-cells-3m-Lymphocytic-immature_B_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	RASGRP1 ACTB BLNK IRF5 UNC93B1	3.02e-05	195	82	5	d77423d0ec64b397c6d1eec181c5fc0acaa92d63
ToppCell	facs-Marrow-B-cells-3m-Lymphocytic-immature_B_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	RASGRP1 ACTB BLNK IRF5 UNC93B1	3.02e-05	195	82	5	f5bf4797972185afa76638293166abd536e5472f
ToppCell	renal_medulla_nuclei-CKD+DKD_normotensive-Endothelial-blood_vessel_endothelial_cell_of_kidney\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	PCED1B BMPR2 RASGRF2 HIF3A APP	3.10e-05	196	82	5	22767bcf0095d9eb0cbed7cdc74e4d32d9357e1b
ToppCell	renal_medulla_nuclei-CKD+DKD_normotensive-Endothelial\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	PCED1B BMPR2 RASGRF2 HIF3A APP	3.10e-05	196	82	5	adee900dcd16dbaba15c58bdcace09ba20214950
ToppCell	(1)_T_cells-(1)_T_CD8_CytT\|(1)_T_cells / Lung cell shreds - cell class (v4) and cell subclass (v4)	GTF3C1 ACTB MYO1F ACTG1 YBX3	3.10e-05	196	82	5	3a4ba9ca84ce6b35038765da8c55812587b58bc2
ToppCell	3'-Airway_Nasal-Epithelial-Epithelial_transtional-secretory-club_cell-Club_(nasal)-Club_(nasal)_L.0.2.3.1\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	LIMA1 OTX2 RBBP8 YBX3 MUC4	3.41e-05	200	82	5	0f6620a5baace704518d42fa2f3f90751240f7dd
ToppCell	Bronchial-NucSeq-Immune_Lymphocytic-T\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	PCED1B RASGRP1 RASGRF2 MYO1F PZP	3.41e-05	200	82	5	c6c2b39359c65c9444987d02d1c899dff2ad1366
ToppCell	Bronchial-NucSeq-Immune_Lymphocytic-T-T_CD8\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	PCED1B RASGRP1 RASGRF2 MYO1F PZP	3.41e-05	200	82	5	02c4169a23e5aaa0d4bfc78b51ba19ce8157dc3e
ToppCell	LPS_only-Myeloid-Monocytes,_Macrophages-Erythroid\|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	ANKRD9 SIGLEC10 IRF5 GPANK1	1.27e-04	139	82	4	d96e5c17582f1576fa09d6bad35c418b6248448c
ToppCell	BLOOD--(0)_NK_cell-(0)_NK_cells_(CD56dim-like)\|(0)_NK_cell / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)	GTF3C1 ACTB MYO1F ACTG1	1.49e-04	145	82	4	6dd81d53d006fcc206a10969374a11c372f92133
ToppCell	E16.5-samps-Myeloid-Macrophage\|E16.5-samps / Age Group, Lineage, Cell class and subclass	MYO1F BLNK IRF5 RP1	1.61e-04	148	82	4	cd5f697d8c2f272be1f3f52a05446749278431c5
ToppCell	E16.5-samps-Myeloid-Macrophage-CD163+_Macrophage\|E16.5-samps / Age Group, Lineage, Cell class and subclass	MYO1F BLNK IRF5 RP1	1.61e-04	148	82	4	56e146980a71b5ca655118ae13310c5949220d4a
ToppCell	droplet-Thymus-nan-18m-Myeloid-B_cell\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	BLNK DCBLD1 IRF5 UNC93B1	2.02e-04	157	82	4	a9e077f686382303f0437ebfa4f11d273ba9fe40
ToppCell	facs-Marrow-B-cells-24m-Lymphocytic-precursor_B_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FAT3 PTPRQ COL22A1 C8orf34	2.17e-04	160	82	4	c381ec6be8cf887861cc18f831a20db42f953fe1
ToppCell	facs-Trachea-nan-18m-Myeloid-lymphocyte_of_B_lineage\|Trachea / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PCED1B ANKRD9 BLNK UNC93B1	2.17e-04	160	82	4	5c9281706009558c8361bfa76169f43ffc0f7947
ToppCell	PBMC_fresh-frozen-Severe-critical_progression_d03-09-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD4_c09-GZMK-FOS_l\|Severe-critical_progression_d03-09 / Compartment, severity and other cell annotations on 10x 3' data (130k)	RASGRP1 RASGRF2 PZP TMC3	2.17e-04	160	82	4	79e833c904c762434993b5ec9d5e3540e695fad3
ToppCell	facs-Marrow-B-cells-24m-Lymphocytic-pre_B_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FAT3 PTPRQ COL22A1 C8orf34	2.17e-04	160	82	4	25c8f3d2a6d14ff0ca0b965fce89d3ff22f40585
ToppCell	Myeloid\|World / shred on cell class and cell subclass (v4)	ACTB MYO1F IRF5 UNC93B1	2.22e-04	161	82	4	aee407d3739dba2d5216dcdb1579e7e4f483123d
ToppCell	Immune_cells-B_cell\|World / Lineage and Cell class	RASGRP1 BLNK IRF5 UNC93B1	2.33e-04	163	82	4	3a02465de7c2f7cea227e289fb082a1fb6400301
ToppCell	COVID-mono3\|COVID / Condition, Cell_class and T cell subcluster	ANKRD9 COL22A1 CGNL1 PLEKHA6	2.33e-04	163	82	4	6ab4cbcd411b40920b81162c0f4b03ea67408f52
ToppCell	COVID-mono3-\|COVID / Condition, Cell_class and T cell subcluster	ANKRD9 COL22A1 CGNL1 PLEKHA6	2.33e-04	163	82	4	26661c7a3a0a449ed32d4b3b28fc2fc0b237025d
ToppCell	Globus_pallidus-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)-Igfbp4-Inhibitory_Neuron.Gad1Gad2.Igfbp4.Adora1_(Striatum,_interneuron)-\|Globus_pallidus / BrainAtlas - Mouse McCarroll V32	SPTBN5 COX6A2 TPSG1	2.46e-04	66	82	3	d6b202d9f5bebaac23b34b689ad306549dec0593
ToppCell	Globus_pallidus-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)-Igfbp4-Inhibitory_Neuron.Gad1Gad2.Igfbp4.Adora1_(Striatum,_interneuron)\|Globus_pallidus / BrainAtlas - Mouse McCarroll V32	SPTBN5 COX6A2 TPSG1	2.46e-04	66	82	3	4a714cf035b22da103054098f85f9170c56e9e83
ToppCell	PND01-03-samps-Myeloid\|PND01-03-samps / Age Group, Lineage, Cell class and subclass	ACTB MYO1F IRF5 UNC93B1	2.50e-04	166	82	4	99dc8a186ec12d3563e81fa4618a814740332c73
ToppCell	PND28-Immune-Immune_Myeloid\|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	ACTB MYO1F IRF5 UNC93B1	2.50e-04	166	82	4	caa992944bc7488a6868dbd1902bc3ead6945eb1
ToppCell	facs-MAT-Fat-18m-Myeloid-macrophage\|MAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ACTB MYO1F IRF5 UNC93B1	2.56e-04	167	82	4	c2952d8ba763374c5678b92825c8956fc3e3ecd2
ToppCell	facs-SCAT-Fat-18m-Myeloid-myeloid_cell\|SCAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ACTB MYO1F IRF5 UNC93B1	2.67e-04	169	82	4	1e34a13a450f90b79fcaacd72ad3a7aa21e5eed2
ToppCell	facs-Liver-Non-hepatocytes-24m-Myeloid-nan\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ACTB MYO1F IRF5 UNC93B1	2.67e-04	169	82	4	2d3618f78484bd3508b7bdae3a0d0183cdae5057
ToppCell	Primary_Visual_cortex_(V1C)-Neuronal-Glutamatergic_Excit-Glut_A_(CT)-Glut_CT2_L6_FEZF2-Exc_L6_FEZF2_ETV4\|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	SPTBN5 RASGRP1 DCBLD1 CGNL1	2.67e-04	169	82	4	716e9d4c5fb99c56b76afaa5ed90bfa859fde802
ToppCell	facs-SCAT-Fat-18m-Myeloid\|SCAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ACTB MYO1F IRF5 UNC93B1	2.67e-04	169	82	4	dbc6f95b4a0d9bc2a34f649161b83979e5e6fb8e
ToppCell	facs-GAT-Fat-18m-Myeloid-nan\|GAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ACTB MYO1F IRF5 UNC93B1	2.67e-04	169	82	4	7a7416fcbffcf57d19b477d9da091e04e3499524
ToppCell	facs-SCAT-Fat-18m-Myeloid-nan\|SCAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ACTB MYO1F IRF5 UNC93B1	2.67e-04	169	82	4	4d783e27fd7d25d9c157b98ae7df55acb1e72d4b
ToppCell	Smart-seq2-blood_(Smart-seq2)\|Smart-seq2 / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type	ACTB MYO1F YBX3 UNC93B1	2.67e-04	169	82	4	0ee74cc97a2db9cc16dc73424f74747afe13af90
ToppCell	facs-Trachea-nan-24m-Myeloid-nan\|Trachea / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MYO1F BLNK IRF5 UNC93B1	2.67e-04	169	82	4	87e95804b3b19c245cea6293d72b64351293b0e8
ToppCell	droplet-Trachea-3m-Hematologic-myeloid-granulocyte-granulocyte_l12\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	MYO1F BLNK IRF5 UNC93B1	2.67e-04	169	82	4	ae975e982faf2f161fbba8edb919981e54d9ce17
ToppCell	facs-GAT-Fat-18m-Myeloid\|GAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ACTB MYO1F IRF5 UNC93B1	2.67e-04	169	82	4	0e1a99cd77edcf32bcb513abd247b2b27409ac63
ToppCell	facs-GAT-Fat-18m-Myeloid-myeloid_cell\|GAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ACTB MYO1F IRF5 UNC93B1	2.67e-04	169	82	4	9bbad31ef03078f5aa456f2e1b17b49c91545ff0
ToppCell	facs-Liver-Non-hepatocytes-24m-Myeloid\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ACTB MYO1F IRF5 UNC93B1	2.74e-04	170	82	4	f08aa6168ff0c20b2083dbf588dd3294e3d9580e
ToppCell	facs-Trachea-3m-Hematologic-myeloid-tracheal_macrophage-macrophage_of_tracheal_l12\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	MYO1F BLNK IRF5 UNC93B1	2.74e-04	170	82	4	f524b73d65941ebef7671c46df4362a3f15d24fc
ToppCell	droplet-Heart-nan-18m-Hematologic-leukocyte\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MYO1F BLNK IRF5 UNC93B1	2.74e-04	170	82	4	7077eaf68ac859f63d6581d26a95c20d6a04bd28
ToppCell	droplet-Spleen-nan-18m-Myeloid-macrophage_dendritic_cell_progenitor\|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TMEM221 IQSEC2 COX6A2 CGNL1	2.80e-04	171	82	4	4e856441063e9825b6f87a1d3dd19c77dae4662c
ToppCell	droplet-Heart-nan-18m-Hematologic\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MYO1F BLNK IRF5 UNC93B1	2.80e-04	171	82	4	2594ba8236a69461d9786ffcd882c39d0c9d5788
ToppCell	droplet-Thymus-nan-21m-Myeloid-B_cell\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	OTX2 BLNK IRF5 UNC93B1	2.80e-04	171	82	4	8bed33f61f7d12a1ac4fba33f730d839f5ee7bef
ToppCell	5'-Adult-SmallIntestine-Hematopoietic-T_cells-CX3CR1+_CD8_Tmem\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	RASGRP1 ZNF469 MYO1F PZP	2.80e-04	171	82	4	187b396059f8802265f54bad2b4882cebb809419
ToppCell	droplet-Heart-nan-18m-Hematologic-leukocyte\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MYO1F BLNK IRF5 UNC93B1	2.80e-04	171	82	4	79b806194df645cccd357520eb6801ab1e93b3c5
ToppCell	facs-Trachea-nan-18m-Myeloid\|Trachea / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MYO1F BLNK IRF5 UNC93B1	2.80e-04	171	82	4	9d496a6edac9663791cda684188d49895246f6fe
ToppCell	droplet-Fat-BAT+GAT+MAT-30m-Myeloid-myeloid_cell\|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MYO1F BLNK IRF5 UNC93B1	2.86e-04	172	82	4	6b01448443cf8392ed8248ff452b80c31240b85d
ToppCell	droplet-Fat-BAT+GAT+MAT-30m-Myeloid\|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MYO1F BLNK IRF5 UNC93B1	2.86e-04	172	82	4	0c0ae2da3cba6022403434567800f16e61a34a2b
ToppCell	facs-Heart-LV-3m-Endothelial-endothelial_cell_of_endocardium\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	BMPR2 CSN3 DCBLD1 CGNL1	2.86e-04	172	82	4	f2c17c49b375b28ad47dc6cabda62f1c238023dd
ToppCell	droplet-Fat-BAT+GAT+MAT-30m-Myeloid-nan\|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MYO1F BLNK IRF5 UNC93B1	2.86e-04	172	82	4	d80c207f3489be2da2f40f47a7835cb73c949c3e
ToppCell	facs-Trachea-nan-24m-Myeloid\|Trachea / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MYO1F BLNK IRF5 UNC93B1	2.86e-04	172	82	4	50374d88ab44b32517e2a8cb70998bbe1ff8ee07
ToppCell	facs-Heart-LV-3m-Endothelial-endocardial_cell\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	BMPR2 CSN3 DCBLD1 CGNL1	2.86e-04	172	82	4	6ab4f01098dddb789df298ddf97b3c384405ee6c
ToppCell	droplet-Lung-30m-Hematologic-myeloid-plasmacytoid_dendritic_cell\|30m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	TMEM221 COX6A2 BLNK CGNL1	2.92e-04	173	82	4	4f0c065e876197ad8cae7856669f09e37ecafa3f
ToppCell	PND03-Immune-Immune_Myeloid-Monocytic-Macrophage-iMON\|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	ACTB MYO1F IRF5 UNC93B1	2.92e-04	173	82	4	6d29e142d043dfd1ed442812358ac463b63b5e3f
ToppCell	facs-Trachea-nan-3m-Myeloid-nan\|Trachea / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MYO1F BLNK IRF5 UNC93B1	2.92e-04	173	82	4	e4eb2ac2cee16bfa8eabc938f8030ee161c972c5
ToppCell	facs-Trachea-nan-3m-Myeloid\|Trachea / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MYO1F BLNK IRF5 UNC93B1	2.92e-04	173	82	4	371515471459307a3b2adce735263b4aac828956
ToppCell	droplet-Lung-30m-Hematologic-myeloid-plasmacytoid_dendritic_cell-plasmacytoid_dendritic\|30m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	TMEM221 COX6A2 BLNK CGNL1	2.92e-04	173	82	4	9bbea566964281f47bf75d665b7d69ba8326e207
ToppCell	facs-Trachea-nan-3m-Myeloid-macrophage\|Trachea / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MYO1F BLNK IRF5 UNC93B1	2.92e-04	173	82	4	4e9b6c71030ae0d63d54e7255e4a10b25970fcc4
ToppCell	facs-Trachea-24m-Hematologic-myeloid-tracheal_macrophage\|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	MYO1F BLNK IRF5 UNC93B1	2.92e-04	173	82	4	7300b1ea8090cc5cd327a7207330eca538c27e63
ToppCell	facs-Trachea-3m-Hematologic-myeloid-tracheal_macrophage\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	MYO1F BLNK IRF5 UNC93B1	2.99e-04	174	82	4	d67fc8e30cc67fff8f7fdeaccb409d12ca0992c1
ToppCell	droplet-Lung-nan-21m-Lymphocytic-Plasma_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ATF5 CSN3 COX6A2 BLNK	2.99e-04	174	82	4	3f4277763e312b46ebd4401ea4a2f5d4c850c768
ToppCell	Control-Epithelial_cells-AT1\|Control / group, cell type (main and fine annotations)	PTPRQ KHDRBS2 RP1 CGNL1	2.99e-04	174	82	4	548d7f2b958a2bfd2c95eb049ceaab55a559c77d
ToppCell	facs-Trachea-24m-Hematologic-myeloid\|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	MYO1F BLNK IRF5 UNC93B1	2.99e-04	174	82	4	2f25fba5225f4687df4396645e94565a640b5583
ToppCell	droplet-Lung-nan-21m-Lymphocytic-plasma_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ATF5 CSN3 COX6A2 BLNK	2.99e-04	174	82	4	fad66d1a8407574b6a835e0bdb824a53afa58650
ToppCell	droplet-Lung-21m-Hematologic-lymphocytic-plasma_cell-plasma_cell\|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	ATF5 CSN3 COX6A2 BLNK	3.05e-04	175	82	4	28b29f844fa46fe579ddc19039fb2d9dc5f48f3b
ToppCell	facs-Trachea-3m-Hematologic-myeloid\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	MYO1F BLNK IRF5 UNC93B1	3.05e-04	175	82	4	22fd7d9b4d403cc8061316855f78bad0eb705ce9
ToppCell	droplet-Lung-21m-Hematologic-lymphocytic-plasma_cell\|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	ATF5 CSN3 COX6A2 BLNK	3.05e-04	175	82	4	ac96ca9ca309b0d72a2f5af6a3b02c7f80755750
ToppCell	3'-GW_trimst-1-LargeIntestine-Hematopoietic-Myeloid-Macrophages\|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	MYO1F SIGLEC10 BLNK IRF5	3.05e-04	175	82	4	fe27c3279f660b5be4193005394b77163c599d32
ToppCell	10x5'v1-week_14-16-Myeloid_DC-DC-tDC\|week_14-16 / cell types per 3 fetal stages;per 3',per 5'	LIMA1 ACTB ACTG1 IRF5	3.12e-04	176	82	4	fb07a047a3a7a8d03bfcc28eea3da2eaa0f6b733
ToppCell	PND07-Immune\|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	ACTB MYO1F IRF5 UNC93B1	3.12e-04	176	82	4	2f87f49b64c6f89823d540172a8e923ebaa6d6cd
ToppCell	10x3'2.3-week_12-13-Myeloid_DC-DC-pDC\|week_12-13 / cell types per 3 fetal stages;per 3',per 5'	PCED1B BLNK APP PZP	3.19e-04	177	82	4	e36c2005be74ee8ff03c2052504cb496faf86009
ToppCell	facs-Lung-3m-Hematologic\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	ACTB MYO1F IRF5 UNC93B1	3.19e-04	177	82	4	a8a7b135d86701ab9acac8273061debf8cce79a0
ToppCell	facs-Lung-EPCAM-3m-Myeloid\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ACTB MYO1F IRF5 UNC93B1	3.26e-04	178	82	4	01c90c3952220cc4d6a7ed9c4d575fe4f2f80fd1
ToppCell	Fetal_29-31_weeks-Epithelial-alveolar_epithelial_cell_type_2/Club-like_(AT2/Club-like)-D150\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	KHDRBS2 RP1 HIF3A C8orf34	3.33e-04	179	82	4	815b959ce8721c5ded70c0ca6e318dafc691746e
ToppCell	Children_(3_yrs)-Epithelial-alveolar_epithelial_cell_type_1-D046\|Children_(3_yrs) / Lineage, Cell type, age group and donor	PTPRQ KHDRBS2 RP1 CGNL1	3.33e-04	179	82	4	4f6ca313b78aa93557937a046c44dcf8bcc9963c
ToppCell	droplet-Marrow-nan-18m-Lymphocytic-precursor_B_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TMEM221 COX6A2 BLNK UNC93B1	3.33e-04	179	82	4	1757b9f3f4c634277a67c4f5a39d27d6b4937073
ToppCell	Hippocampus-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)-Tac1\|Hippocampus / BrainAtlas - Mouse McCarroll V32	COX6A2 RP1 MUC4	3.45e-04	74	82	3	c652ef04a1b8716b954ce913daa481cc02f4d44e
ToppCell	HSPCs-Mono_prog.\|HSPCs / Lineage and Cell class	MYO1F IRF5 UNC93B1 APP	3.47e-04	181	82	4	a188f0d22426d8723ba394d94d20431afa6722a7
ToppCell	droplet-Marrow-BM-30m-Lymphocytic-nan\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CA11 CSN3 COX6A2 BLNK	3.47e-04	181	82	4	cd46eba2e03fd15d8de8e875793ae2f51fa98b3b
ToppCell	droplet-Marrow-BM-30m-Lymphocytic\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CA11 CSN3 COX6A2 BLNK	3.47e-04	181	82	4	c7d12c7de227c9433ec2303b8929e957b833f59b
ToppCell	ASK454-Epithelial\|ASK454 / Donor, Lineage and Cell class of Lung cells from Dropseq	RBBP8 ANKRD9 KHDRBS2 RP1	3.54e-04	182	82	4	ab15316cff989b61ff397a866d7ca8b49c13e981
ToppCell	droplet-Marrow-BM_(NON-STC)-30m-Lymphocytic-precursor_B_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TMEM221 COX6A2 BLNK UNC93B1	3.54e-04	182	82	4	33afbb7c4352b03266501b1f4f0e751c12c7350d
ToppCell	Dendritic_Cells-HP_01\|World / lung cells shred on cell class, cell subclass, sample id	ATF5 ACTB MYO1F SIGLEC10	3.62e-04	183	82	4	499da89b4abe7b746e703cd1e5c56f9b1d97ac3c
ToppCell	Mesenchymal_cells-Osteoblasts\|Mesenchymal_cells / Lineage and Cell class	ZNF469 FAT3 DCBLD1 COL22A1	3.62e-04	183	82	4	d6b52d52fe9a7a6c798947f05420d79fe12e4662
ToppCell	3'-Child09-12-SmallIntestine-Hematopoietic-B_cells-FCRL4+_Memory_B\|Child09-12 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	SIGLEC10 BLNK ACTG1 UNC93B1	3.69e-04	184	82	4	95cf125127658c4c04445c61809d1aed21ee1f83
ToppCell	3'-Child09-12-SmallIntestine-Endothelial-blood_vessel_EC-Mature_arterial_EC\|Child09-12 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	YBX3 RP1 HIF3A PZP	3.69e-04	184	82	4	842473fa415575441b595073a994b6d621169776
ToppCell	Children_(3_yrs)-Epithelial-alveolar_epithelial_cell_type_1\|Children_(3_yrs) / Lineage, Cell type, age group and donor	PTPRQ KHDRBS2 RP1 CGNL1	3.77e-04	185	82	4	1c222f7285d6e3dae0354dc7e853ddc0ea55e63e
ToppCell	droplet-Marrow-nan-18m-Lymphocytic-late_pro-B_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CA11 CSN3 BLNK ACP4	3.77e-04	185	82	4	238938a4682b44e88a30b86b13af4feeabe9553d
ToppCell	3'-Pediatric_IBD-SmallIntestine-Hematopoietic-T_cells-Th1\|Pediatric_IBD / Celltypes from developing, pediatric, Crohn's, & adult GI tract	RASGRP1 ACTB MYO1F ACTG1	3.77e-04	185	82	4	326c8b6ea0e9140616d7b867db1385b980dc3678
ToppCell	Control-T_cells-CD8+_T_cells\|Control / group, cell type (main and fine annotations)	PCED1B RASGRP1 MYO1F PZP	3.77e-04	185	82	4	02ab64c0166c0646d1d4c6ed110ef0b75a1096d0
Drug	diphenylglyoxal bis(guanylhydrazone	AOC2 AOC3	1.25e-05	2	81	2	CID000357080
Drug	AC1Q77R6	AOC2 AOC3	1.25e-05	2	81	2	CID000094259
Drug	DPGBG	AOC2 AOC3	1.25e-05	2	81	2	CID005356884
Drug	monopropionylcadaverine	AOC2 AOC3	1.25e-05	2	81	2	CID000194207
Drug	p-dimethylaminomethylbenzaldehyde	AOC2 AOC3	1.25e-05	2	81	2	CID000193251
Drug	1-carboxymethylpyridinium	AOC2 AOC3	1.25e-05	2	81	2	CID000080439
Drug	isoputreanine	AOC2 AOC3	1.25e-05	2	81	2	CID000171763
Drug	supinidine	AOC2 AOC3	1.25e-05	2	81	2	CID000164663
Drug	N-(3-aminopropyl)pyrrolidin-2-one	AOC2 AOC3	1.25e-05	2	81	2	CID000082111
Drug	o-aminobenzaldehyde	AOC2 AOC3 PHIP	2.35e-05	16	81	3	CID000068255
Drug	methylimidazoleacetic acid	AOC2 AOC3 TPSG1	2.85e-05	17	81	3	CID000075810
Drug	2-bromoethylamine	ERF AOC2 AOC3	3.41e-05	18	81	3	CID000007851
Drug	AC1L1B7L	AOC2 AOC3	3.74e-05	3	81	2	CID000026477
Drug	3-aminopropionamide	AOC2 AOC3	3.74e-05	3	81	2	CID000192802
Drug	pentafluorobenzamide	AOC2 AOC3	3.74e-05	3	81	2	CID000069547
Drug	acisoga	AOC2 AOC3	3.74e-05	3	81	2	CID000129397
Drug	(+)-Cyanustine	AOC2 AOC3	3.74e-05	3	81	2	CID000028846
Drug	propylglyoxal	AOC2 AOC3	3.74e-05	3	81	2	CID000123249
Drug	3-Hydroxycadaverine	AOC2 AOC3	3.74e-05	3	81	2	CID000435285
Drug	5-fluoropentane-1,4-diamine	AOC2 AOC3	3.74e-05	3	81	2	CID010011890
Drug	NSD-1531	AOC2 AOC3	3.74e-05	3	81	2	CID003014318
Drug	Nazlinine	AOC2 AOC3	3.74e-05	3	81	2	CID000126237
Drug	5-aminopentanal	AOC2 AOC3	3.74e-05	3	81	2	CID000443849
Drug	necic acid	AOC2 AOC3	3.74e-05	3	81	2	CID006440847
Drug	AC1L34PU	AOC2 AOC3	3.74e-05	3	81	2	CID000134498
Drug	h202	AOC2 AOC3	3.74e-05	3	81	2	CID000013826
Drug	amicarbalide	AOC2 AOC3	3.74e-05	3	81	2	CID000072074
Drug	N-(4-aminobutyl)aziridine	AOC2 AOC3	3.74e-05	3	81	2	CID000152643
Drug	tin dibromide	TPSG1 PHIP	3.74e-05	3	81	2	CID000066224
Drug	C10974	AOC2 AOC3	3.74e-05	3	81	2	CID000443042
Drug	alpha-difluoromethyl putrescine	AOC2 AOC3	3.74e-05	3	81	2	CID000135151
Drug	ketosuccinamate	AOC2 AOC3	3.74e-05	3	81	2	CID000439716
Drug	N-(3-aminopropyl)aziridine	AOC2 AOC3	3.74e-05	3	81	2	CID000014076
Drug	ethylmethylglyoxal bis(guanylhydrazone	AOC2 AOC3	3.74e-05	3	81	2	CID000129202
Drug	4-Di	AOC2 ACTB AOC3	4.73e-05	20	81	3	CID000005227
Drug	Cephalexin monohydrate [23325-78-2]; Down 200; 11uM; MCF7; HT_HG-U133A	VPS9D1 PI4KB MYO1F PLEKHA6 RAD54L2 APP	7.36e-05	197	81	6	5250_DN
Drug	malonamate	AOC2 AOC3	7.47e-05	4	81	2	CID000075367
Drug	2-aminoresorcinol	AOC2 AOC3	7.47e-05	4	81	2	CID000069450
Drug	Eovist (TN)	AOC2 AOC3	7.47e-05	4	81	2	CID009961939
Drug	AC1Q3E6A	AOC2 AOC3	7.47e-05	4	81	2	CID000068318
Drug	spermic acid	AOC2 AOC3	7.47e-05	4	81	2	CID000167029
Drug	N-acetyl-1,6-diaminohexane	AOC2 AOC3	7.47e-05	4	81	2	CID000162081
Drug	3-aminooxy-2-fluoro-1-propanamine	AOC2 AOC3	7.47e-05	4	81	2	CID000126496
Drug	2-Butene-1,4-diamine	AOC2 AOC3	7.47e-05	4	81	2	CID000148401
Drug	lanthionamine	AOC2 AOC3	7.47e-05	4	81	2	CID000070096
Drug	N-methylpyrrolinium	AOC2 AOC3	7.47e-05	4	81	2	CID000440932
Drug	dimethylpyridine	AOC2 AOC3	7.47e-05	4	81	2	CID000011420
Drug	1,4-diamino-2-butyne	AOC2 AOC3	7.47e-05	4	81	2	CID000124159
Drug	0198306-0000 [212631-61-3]; Up 200; 10uM; MCF7; HT_HG-U133A	VPS9D1 BLNK IRF5 RAD54L2 TSFM AXIN1	7.57e-05	198	81	6	7064_UP
Drug	ammonia	NT5C1A CSN3 AOC2 ACTB AOC3 ACTG1 TBXT ACP4 TSFM	8.14e-05	509	81	9	CID000000222
Drug	cadaverine	CSN3 AOC2 AOC3 ACTG1	1.14e-04	70	81	4	CID000000273
Drug	piperideine	AOC2 AOC3	1.24e-04	5	81	2	CID000068161
Drug	geranylamine	AOC2 AOC3	1.24e-04	5	81	2	CID000160248
Drug	phenamidine	AOC2 AOC3	1.24e-04	5	81	2	CID000064948
Drug	NSD 1039	AOC2 AOC3	1.24e-04	5	81	2	CID000193408
Drug	NSD 1024	AOC2 AOC3	1.24e-04	5	81	2	CID000188951
Drug	N(8)-(2-carboxyethyl)spermidine	AOC2 AOC3	1.24e-04	5	81	2	CID000125245
Drug	Nsc82118	AOC2 AOC3	1.24e-04	5	81	2	CID000164749
Drug	oxosparteine	AOC2 AOC3	1.24e-04	5	81	2	CID000097492
Drug	alpha-hydrazinohistidine	AOC2 AOC3	1.24e-04	5	81	2	CID000169499
Drug	perhydroazepinyl	AOC2 AOC3	1.24e-04	5	81	2	CID000123152
Drug	2-fluoroputrescine	AOC2 AOC3	1.24e-04	5	81	2	CID000147066
Drug	pelletierine	AOC2 AOC3	1.24e-04	5	81	2	CID000092987
Drug	1,4-diamino-2-butanone	AOC2 AOC3	1.24e-04	5	81	2	CID000151733
Drug	tyrosine	UBR5 AOC2 AOC3	1.48e-04	29	81	3	CID005460802
Drug	3-aminopropanal	AOC2 AOC3 TPSG1	1.64e-04	30	81	3	CID000000075
Drug	NSC614854	AOC2 AOC3	1.86e-04	6	81	2	CID000122633
Drug	isothiouronium	AOC2 AOC3	1.86e-04	6	81	2	CID000031429
Drug	trihydroxyphenylalanine	AOC2 AOC3	1.86e-04	6	81	2	CID000591034
Drug	cyclohexanone oxime	AOC2 AOC3	1.86e-04	6	81	2	CID000007517
Drug	ethylglyoxal	AOC2 AOC3	1.86e-04	6	81	2	CID000145744
Drug	FF-705	AOC2 AOC3	1.86e-04	6	81	2	CID000126643
Drug	1,4-dimethylputrescine	AOC2 AOC3	1.86e-04	6	81	2	CID000162247
Drug	a-em	APP TPSG1 VEGFD	2.19e-04	33	81	3	CID004471892
Drug	putreanine	AOC2 AOC3	2.59e-04	7	81	2	CID000161506
Drug	AC1L3Y6U	AOC2 AOC3	2.59e-04	7	81	2	CID000097282
Drug	GYKI 11.121	AOC2 AOC3	2.59e-04	7	81	2	CID000193769
Drug	p-dimethylaminomethylbenzylamine	AOC2 AOC3	2.59e-04	7	81	2	CID000193714
Drug	2-hydrazinopyridine	AOC2 AOC3	2.59e-04	7	81	2	CID000078645
Drug	AC1L28PE	AOC2 AOC3	2.59e-04	7	81	2	CID000067954
Drug	tele-methylhistamine	AOC2 AOC3 TPSG1	3.35e-04	38	81	3	CID000003614
Drug	enacyloxin IIa	TSFM TLX2	3.45e-04	8	81	2	CID005288163
Drug	hyamine hydroxide	AOC2 AOC3	3.45e-04	8	81	2	CID000014842
Drug	1,2-diaminoguanidine	AOC2 AOC3	3.45e-04	8	81	2	CID000170039
Drug	NSC-356893	AOC2 AOC3	3.45e-04	8	81	2	CID000434770
Drug	Z H-H	AOC2 AOC3	3.45e-04	8	81	2	CID000004657
Drug	Q 192	AOC2 AOC3	3.45e-04	8	81	2	CID000077317
Disease	Iris Coloboma with Ptosis, Hypertelorism, and Mental Retardation	ACTB ACTG1	7.63e-06	2	82	2	C1855722
Disease	Baraitser-Winter syndrome	ACTB ACTG1	7.63e-06	2	82	2	cv:C1853623
Disease	Fryns-Aftimos Syndrome	ACTB ACTG1	7.63e-06	2	82	2	C1853623
Disease	Uveoretinal Coloboma	ACTB ACTG1	1.59e-04	7	82	2	C4554007
Disease	retinal detachment	FAT3 COL22A1	1.59e-04	7	82	2	EFO_0005773
Disease	autosomal dominant nonsyndromic deafness 20 (implicated_via_orthology)	ACTB ACTG1	2.11e-04	8	82	2	DOID:0110550 (implicated_via_orthology)
Disease	Baraitser-Winter syndrome 1 (implicated_via_orthology)	ACTB ACTG1	2.11e-04	8	82	2	DOID:0081112 (implicated_via_orthology)
Disease	Moyamoya disease (implicated_via_orthology)	ACTB ACTG1	2.11e-04	8	82	2	DOID:13099 (implicated_via_orthology)
Disease	thoracic aortic aneurysm (implicated_via_orthology)	ACTB ACTG1	2.11e-04	8	82	2	DOID:14004 (implicated_via_orthology)
Disease	Congenital ocular coloboma (disorder)	ACTB ACTG1	2.71e-04	9	82	2	C0009363
Disease	Congenital neurologic anomalies	ACTB ACTG1	3.38e-04	10	82	2	C0497552
Disease	intestinal atresia (implicated_via_orthology)	ACTB ACTG1	3.38e-04	10	82	2	DOID:10486 (implicated_via_orthology)
Disease	Cranioschisis	ACTB ACTG1	3.38e-04	10	82	2	C0265541
Disease	patent ductus arteriosus (implicated_via_orthology)	ACTB ACTG1	3.38e-04	10	82	2	DOID:13832 (implicated_via_orthology)
Disease	gastric adenocarcinoma (is_implicated_in)	KMT2D UBR5	4.13e-04	11	82	2	DOID:3717 (is_implicated_in)
Disease	intracranial aneurysm (is_implicated_in)	KMT2D COL22A1	4.94e-04	12	82	2	DOID:10941 (is_implicated_in)
Disease	Animal Mammary Neoplasms	RASGRF2 CSN3 ACTB ACTG1	6.72e-04	142	82	4	C0024667
Disease	Mammary Carcinoma, Animal	RASGRF2 CSN3 ACTB ACTG1	6.72e-04	142	82	4	C1257925
Disease	response to irinotecan	DCBLD1 C8orf34	7.82e-04	15	82	2	EFO_0004829
Disease	Mammary Neoplasms, Experimental	RASGRF2 CSN3 ACTB ACTG1	9.32e-04	155	82	4	C0024668
Disease	Carcinomatosis	RASGRF2 CSN3 ACTB ACTG1	1.12e-03	163	82	4	C0205699
Disease	Carcinoma, Spindle-Cell	RASGRF2 CSN3 ACTB ACTG1	1.12e-03	163	82	4	C0205697
Disease	Undifferentiated carcinoma	RASGRF2 CSN3 ACTB ACTG1	1.12e-03	163	82	4	C0205698
Disease	Anaplastic carcinoma	RASGRF2 CSN3 ACTB ACTG1	1.12e-03	163	82	4	C0205696
Disease	Carcinoma	RASGRF2 CSN3 ACTB ACTG1	1.15e-03	164	82	4	C0007097
Disease	axial length measurement	ZNF469 ZNRF3 AXIN1	1.30e-03	77	82	3	EFO_0005318
Disease	Bipolar Disorder	VGF RASGRP1 OTX2 ATF5 ACTB APP	2.15e-03	477	82	6	C0005586
Disease	lymphocyte count	CA11 NCOR1 ZNF469 LIMA1 ZNRF3 RBBP8 ACTB IRF5 HIF3A PLEKHA6 RFX7	2.38e-03	1464	82	11	EFO_0004587
Disease	Adenocarcinoma of large intestine	ZNRF3 UBR5 AXIN1	2.45e-03	96	82	3	C1319315

Protein segments in the cluster

Peptide	Gene	Start	Entry
PLARLPHDPGVFRVY	ERF	221	P50548
RRTPDGHPVRQSYRL	ASH1L	2676	Q9NR48
SRHRFRYIPPNTPEN	RBBP8	836	Q99708
HVPYGVAQTPRRTAP	NT5C1A	346	Q9BXI3
YITALQAVPPRPRHV	APP	476	P05067
APRAVFPSIVGRPRH	ACTB	26	P60709
APRAVFPSIVGRPRH	ACTG1	26	P63261
YAREPRNHRAPPLTP	RASGRP1	431	O95267
RPGFRLSAPHARVAP	C8orf34	16	Q49A92
IQQHYRSYRRRPGPP	CAMTA2	1131	O94983
YNTGRHVSFLPAPRP	CA11	101	O75493
RSRKGHLPAPVQPYE	RAD54L2	1271	Q9Y4B4
LRYCTPRGRFVHVPP	CYB5D1	91	Q6P9G0
RRPGAPAYNRPHRYS	CCER1	41	Q8TC90
TVERHGGPLPYHRRP	AOC3	156	Q16853
RLAPYPHPATTRGDR	ATF5	196	Q9Y2D1
RRKPAYVPEASRPHQ	NUMBL	51	Q9Y6R0
RPQRPKAPVGHLYQT	PZP	1191	P20742
YHRSRPQHLPRGLYP	QRICH2	1566	Q9H0J4
HGGPLPYHRRPVLRA	AOC2	156	O75106
QRRPHVGCATYRPPQ	MUC4	4666	Q99102
RSPPEALVQGRYPHI	LIMA1	131	Q9UHB6
LGYRSAPQPRVTHFP	GPANK1	296	O95872
PQHYTLGRPGRAPRR	IQSEC2	1331	Q5JU85
GAQPSPPTVYHERQR	JOSD2	6	Q8TAC2
QSPQPRHTFYAGPRL	TSFM	26	P43897
TPRYQRPAPVVHRGF	PCED1B	386	Q96HM7
RPAPVVHRGFGRYRP	PCED1B	391	Q96HM7
YRGRPPRALTISNPH	IRF5	256	Q13568
HPSVGYPATPRKQRR	OTX1	26	P32242
QTPRHVRPPLVTYER	PTPRQ	1136	Q9UMZ3
RFYQLTAPARPPAHG	ACP4	361	Q9BZG2
APQGRAPYHQPPTRR	ERVK-10	236	P87889
RPVHPALPFARGEYI	BLNK	106	Q8WV28
PVYKPAPARNHRPRG	C5orf60	136	A6NFR6
VNRHENRRYIPFLPG	CGNL1	326	Q0VF96
SGHRPRPEFRPYQHL	COX6A2	51	Q02221
QVNGRVPLPHIPRTY	AXIN1	361	O15169
RRRPQFHPSQYLPPH	FAT3	4451	Q8TDW7
LSHNRRVPKIGPYPD	BMPR2	531	Q13873
AAPGPHVALAVRYNR	ANKRD9	111	Q96BM1
PHAGGRPRDRAYKQV	COL22A1	131	Q8NFW1
APYRHLPASRVVGTP	FBXO24	486	O75426
APPQRSARGGYREHP	KHDRBS2	331	Q5VWX1
RQYLPNSHPPTVVRR	CSN3	96	P07498
PQRAGRHEYALPLAP	DCBLD1	581	Q8N8Z6
FVYPGNPLRHPDLVR	FAM120B	651	Q96EK7
RERRPRYQHPKGAPN	UPF2	1246	Q9HAU5
HPSVGYPATPRKQRR	OTX2	26	P32243
QAKHRFYRPPTPGLR	RP1	441	P56715
YVPKAVSQPRRHSRP	REXO1	201	Q8N1G1
CGRPNRPGVYTRVPA	TPSG1	246	Q9NRR2
LAQGPRPHAPRYYVI	TMC3	876	Q7Z5M5
QPPGYQSRHILLRPT	SUPT20HL1	156	Q3ZLR7
PPSRHYPGREAQARR	VGF	571	O15240
PRHLRYRQPGGQTAD	RASGRF2	856	O14827
EQLPRAYHRPLGAVP	HIF3A	506	Q9Y2N7
RPQERRTSYEPFHPG	NCOR1	81	O75376
PPGNRRYPNHRHRAR	SPP2	191	Q13103
VRRIREGSPYGHLPN	PI4KB	541	Q9UBF8
TLERGAPRRYPHIQA	SPTBN5	3171	Q9NRC6
QPPGYQSRHILLRPT	SUPT20HL2	156	P0C7V6
PDPSPRPAYKVVRRH	PLEKHA6	851	Q9Y2H5
QRPPRGSHAPYLLVF	UNC93B1	206	Q9H1C4
QPRIPRPQHKVRGYR	UNC93B1	526	Q9H1C4
QLQGPVHRNPTYRPR	YBX3	276	P16989
NPHPSRYQRLVPGRE	PHIP	596	Q8WWQ0
QAAFRRYPRGAPAPH	TAPBP	76	O15533
YSPPVARRLGVPVVH	SOGA1	1016	O94964
YEPRIHIVRVGGPQR	TBXT	166	O15178
RSARHRYPQILPKPA	RFX7	326	Q2KHR2
TRRIGHPYQNRTPPK	TLX3	151	O43711
IRNHPRAPVGDMPYR	ZNF229	336	Q9UJW7
PPGGRLTRKRNPHVY	ZNF469	2836	Q96JG9
RYKGRRPESHAPHVP	ZSWIM8	1216	A7E2V4
GPRAVYNPPRAHRNS	nan	51	Q5W150
PRAQPQQGIHRRTPY	TMEM221	206	A6NGB7
RGRQQRVTLPVHYPG	ZNRF3	356	Q9ULT6
PRQHLGPSFPARRYG	nan	21	Q5PR19
AAPIPQPAGRHRRVY	VPS9D1	101	Q9Y2B5
PRHPYSIIRRSIQIP	VEGFD	196	O43915
LRNYHPIVVPGLGRS	GTF3C1	776	Q12789
IRAPSPRRALYHNPP	HIVEP2	2141	P31629
HYATLNFPGVRPRPE	SIGLEC10	666	Q96LC7
YPQLPRCRLGPHTDN	TRIM65	401	Q6PJ69
PAHRQALGERLYPRV	UBR5	2391	O95071
GTRRIGHPYQNRTPP	TLX2	141	O43763
PQRPRFYPVSEDPHR	KMT2D	2901	O14686
KPQPRTHGPRCRALY	MYO1F	1036	O00160