Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	frizzled binding	WNT5B WNT3 WNT9B WNT4	1.11e-05	42	66	4	GO:0005109
GeneOntologyBiologicalProcess	renal vesicle morphogenesis	KIF26B WNT9B WNT4	2.36e-05	18	65	3	GO:0072077
GeneOntologyBiologicalProcess	renal vesicle development	KIF26B WNT9B WNT4	2.79e-05	19	65	3	GO:0072087
GeneOntologyBiologicalProcess	metanephric nephron morphogenesis	KIF26B WNT9B WNT4	5.06e-05	23	65	3	GO:0072273
GeneOntologyBiologicalProcess	metanephros morphogenesis	KIF26B WNT9B WNT4	1.03e-04	29	65	3	GO:0003338
GeneOntologyBiologicalProcess	metanephric tubule formation	WNT9B WNT4	1.45e-04	6	65	2	GO:0072174
GeneOntologyBiologicalProcess	metanephros development	DLG5 KIF26B WNT9B WNT4	2.31e-04	95	65	4	GO:0001656
GeneOntologyBiologicalProcess	metanephric nephron development	KIF26B WNT9B WNT4	2.33e-04	38	65	3	GO:0072210
GeneOntologyBiologicalProcess	midbrain development	DLG5 WNT3 WNT9B APLP2	2.50e-04	97	65	4	GO:0030901
GeneOntologyBiologicalProcess	regulation of electron transfer activity	SPHK2 SCO1	2.70e-04	8	65	2	GO:1904732
GeneOntologyBiologicalProcess	regulation of cytochrome-c oxidase activity	SPHK2 SCO1	2.70e-04	8	65	2	GO:1904959
GeneOntologyBiologicalProcess	renal vesicle formation	KIF26B WNT4	2.70e-04	8	65	2	GO:0072033
HumanPheno	Adrenal gland agenesis	WNT3 WNT4	2.51e-05	2	26	2	HP:0011743
Domain	Wnt	WNT5B WNT3 WNT9B WNT4	5.63e-07	19	67	4	IPR005817
Domain	Wnt_CS	WNT5B WNT3 WNT9B WNT4	5.63e-07	19	67	4	IPR018161
Domain	wnt	WNT5B WNT3 WNT9B WNT4	5.63e-07	19	67	4	PF00110
Domain	WNT1	WNT5B WNT3 WNT9B WNT4	5.63e-07	19	67	4	SM00097
Domain	WNT1	WNT5B WNT3 WNT9B WNT4	5.63e-07	19	67	4	PS00246
Domain	TIL	FCGBP MUC6	8.18e-04	12	67	2	PF01826
Domain	MATH/TRAF_dom	USP7 TRIM37	8.18e-04	12	67	2	IPR002083
Domain	MATH	USP7 TRIM37	8.18e-04	12	67	2	PS50144
Domain	MATH	USP7 TRIM37	8.18e-04	12	67	2	SM00061
Domain	MATH	USP7 TRIM37	8.18e-04	12	67	2	PF00917
Domain	C8	FCGBP MUC6	8.18e-04	12	67	2	PF08742
Domain	Unchr_dom_Cys-rich	FCGBP MUC6	9.64e-04	13	67	2	IPR014853
Domain	C8	FCGBP MUC6	9.64e-04	13	67	2	SM00832
Domain	TIL_dom	FCGBP MUC6	1.12e-03	14	67	2	IPR002919
Domain	DAGKc	SPHK2 DGKK	1.12e-03	14	67	2	SM00046
Domain	Diacylglycerol_kinase_cat_dom	SPHK2 DGKK	1.29e-03	15	67	2	IPR001206
Domain	DAGK_cat	SPHK2 DGKK	1.29e-03	15	67	2	PF00781
Domain	DAGK	SPHK2 DGKK	1.29e-03	15	67	2	PS50146
Domain	VWD	FCGBP MUC6	1.47e-03	16	67	2	SM00216
Domain	VWF_type-D	FCGBP MUC6	1.47e-03	16	67	2	IPR001846
Domain	VWFD	FCGBP MUC6	1.47e-03	16	67	2	PS51233
Domain	VWD	FCGBP MUC6	1.47e-03	16	67	2	PF00094
Domain	NAD/diacylglycerol_kinase	SPHK2 DGKK	1.67e-03	17	67	2	IPR016064
Domain	VWC_out	FCGBP MUC6	2.08e-03	19	67	2	SM00215
Domain	Actinin_actin-bd_CS	SPTBN5 SYNE1	3.06e-03	23	67	2	IPR001589
Domain	Spectrin	SPTBN5 SYNE1	3.06e-03	23	67	2	PF00435
Domain	ACTININ_2	SPTBN5 SYNE1	3.06e-03	23	67	2	PS00020
Domain	ACTININ_1	SPTBN5 SYNE1	3.06e-03	23	67	2	PS00019
Domain	TRAF-like	USP7 TRIM37	3.33e-03	24	67	2	IPR008974
Domain	ZF_RING_1	LONRF1 RC3H1 TRIM37 CNOT4 MAP3K1	3.90e-03	291	67	5	PS00518
Domain	ZF_RING_2	LONRF1 RC3H1 TRIM37 CNOT4 MAP3K1	4.31e-03	298	67	5	PS50089
Domain	RING	LONRF1 RC3H1 TRIM37 CNOT4 MAP3K1	4.75e-03	305	67	5	SM00184
Domain	Spectrin_repeat	SPTBN5 SYNE1	4.84e-03	29	67	2	IPR002017
Domain	Spectrin/alpha-actinin	SPTBN5 SYNE1	5.87e-03	32	67	2	IPR018159
Domain	SPEC	SPTBN5 SYNE1	5.87e-03	32	67	2	SM00150
Domain	Znf_RING	LONRF1 RC3H1 TRIM37 CNOT4 MAP3K1	6.27e-03	326	67	5	IPR001841
Domain	Znf-RING_LisH	LONRF1 RC3H1	6.60e-03	34	67	2	IPR027370
Domain	zf-RING_UBOX	LONRF1 RC3H1	6.60e-03	34	67	2	PF13445
Pathway	KEGG_MEDICUS_REFERENCE_WNT_SIGNALING_MODULATION_WNT_ACYLATION	WNT5B WNT3 WNT9B WNT4	7.70e-07	19	55	4	M47836
Pathway	REACTOME_WNT_LIGAND_BIOGENESIS_AND_TRAFFICKING	WNT5B WNT3 WNT9B WNT4	2.47e-06	25	55	4	MM14940
Pathway	REACTOME_WNT_LIGAND_BIOGENESIS_AND_TRAFFICKING	WNT5B WNT3 WNT9B WNT4	2.91e-06	26	55	4	M27239
Pathway	KEGG_MEDICUS_REFERENCE_WNT_SIGNALING_MODULATION_WNT_INHIBITOR	WNT5B WNT3 WNT9B WNT4	3.96e-06	28	55	4	M47835
Pathway	KEGG_MEDICUS_VARIANT_MUTATION_INACTIVATED_PTCH1_TO_HEDGEHOG_SIGNALING_PATHWAY	WNT5B WNT3 WNT9B WNT4	4.58e-06	29	55	4	M47372
Pathway	KEGG_MEDICUS_VARIANT_MUTATION_ACTIVATED_SMO_TO_HEDGEHOG_SIGNALING_PATHWAY	WNT5B WNT3 WNT9B WNT4	4.58e-06	29	55	4	M47377
Pathway	WP_WNT_SIGNALING_IN_KIDNEY_DISEASE	WNT5B WNT3 WNT9B WNT4	1.11e-05	36	55	4	M39699
Pathway	KEGG_MEDICUS_VARIANT_FZD7_OVEREXPRESSION_TO_WNT_SIGNALING_PATHWAY	WNT5B WNT3 WNT9B WNT4	1.24e-05	37	55	4	M47411
Pathway	WP_WNT_SIGNALING_IN_KIDNEY_DISEASE	WNT5B WNT3 WNT9B WNT4	2.51e-05	44	55	4	MM15878
Pathway	KEGG_MEDICUS_VARIANT_LRP6_OVEREXPRESSION_TO_WNT_SIGNALING_PATHWAY	WNT5B WNT3 WNT9B WNT4	2.74e-05	45	55	4	M47412
Pathway	KEGG_MEDICUS_REFERENCE_WNT_SIGNALING_PATHWAY	WNT5B WNT3 WNT9B WNT4	3.00e-05	46	55	4	M47409
Pathway	KEGG_BASAL_CELL_CARCINOMA	WNT5B WNT3 WNT9B WNT4	6.10e-05	55	55	4	M17807
Pathway	KEGG_HEDGEHOG_SIGNALING_PATHWAY	WNT5B WNT3 WNT9B WNT4	6.55e-05	56	55	4	M1053
Pathway	WP_POLYCYSTIC_KIDNEY_DISEASE_PATHWAY	WNT5B WNT3 WNT9B WNT4	3.32e-04	85	55	4	M48315
Pathway	KEGG_MELANOGENESIS	WNT5B WNT3 WNT9B WNT4	6.40e-04	101	55	4	M7761
Pathway	WP_WNT_SIGNALING_PATHWAY_AND_PLURIPOTENCY	WNT5B WNT3 WNT9B WNT4	6.40e-04	101	55	4	MM15829
Pathway	WP_WNT_SIGNALING_AND_PLURIPOTENCY	WNT5B WNT3 WNT9B WNT4	6.40e-04	101	55	4	M39387
Pathway	KEGG_FOLATE_BIOSYNTHESIS	FPGS QDPR	8.04e-04	11	55	2	M2220
Pathway	WP_DNA_DAMAGE_RESPONSE_ONLY_ATM_DEPENDENT	WNT5B WNT3 WNT4 MAP3K1	8.81e-04	110	55	4	M39492
Pathway	WP_ESC_PLURIPOTENCY_PATHWAYS	WNT5B WNT3 WNT9B WNT4	1.07e-03	116	55	4	MM15863
Pathway	WP_EMBRYONIC_STEM_CELL_PLURIPOTENCY_PATHWAYS	WNT5B WNT3 WNT9B WNT4	1.11e-03	117	55	4	M39530
Pathway	REACTOME_NEPHRON_DEVELOPMENT	WNT9B WNT4	1.13e-03	13	55	2	M48245
Pathway	WP_OSTEOBLAST_DIFFERENTIATION_AND_RELATED_DISEASES	WNT5B WNT3 WNT9B WNT4	1.14e-03	118	55	4	M39852
Pathway	WP_WNT_SIGNALING	WNT5B WNT3 WNT4	1.72e-03	61	55	3	MM15893
Pubmed	Molecular genetic studies of Wnt signaling in the mouse.	WNT5B WNT3 WNT9B WNT4	2.39e-08	16	68	4	10585256
Pubmed	The Wnts.	WNT5B WNT3 WNT9B WNT4	2.39e-08	16	68	4	9889131
Pubmed	Wnt family proteins are secreted and associated with the cell surface.	WNT5B WNT3 WNT9B WNT4	3.12e-08	17	68	4	8167409
Pubmed	Characterization of Wnt gene expression in developing and postnatal hair follicles and identification of Wnt5a as a target of Sonic hedgehog in hair follicle morphogenesis.	WNT5B WNT3 WNT9B WNT4	5.07e-08	19	68	4	11520664
Pubmed	Increased expression of Wnt2 and SFRP4 in Tsk mouse skin: role of Wnt signaling in altered dermal fibrillin deposition and systemic sclerosis.	WNT5B WNT3 WNT9B WNT4	7.80e-08	21	68	4	17943183
Pubmed	The WNT7b promoter is regulated by TTF-1, GATA6, and Foxa2 in lung epithelium.	WNT5B WNT3 WNT9B WNT4	7.80e-08	21	68	4	11914369
Pubmed	Epithelial Wnt10a Is Essential for Tooth Root Furcation Morphogenesis.	WNT5B WNT3 WNT9B WNT4	7.80e-08	21	68	4	31914354
Pubmed	Activation of beta-Catenin in mouse prostate causes HGPIN and continuous prostate growth after castration.	WNT5B WNT3 WNT9B WNT4	9.52e-08	22	68	4	18991257
Pubmed	Does murine spermatogenesis require WNT signalling? A lesson from Gpr177 conditional knockout mouse models.	WNT5B WNT3 WNT9B WNT4	1.15e-07	23	68	4	27362799
Pubmed	Wnt glycoproteins regulate the expression of FoxN1, the gene defective in nude mice.	WNT5B WNT3 WNT4	1.42e-07	6	68	3	12379851
Pubmed	Activation of the Wnt-beta catenin pathway in a cell population on the surface of the forebrain is essential for the establishment of olfactory axon connections.	WNT5B WNT3 WNT9B WNT4	2.27e-07	27	68	4	17804636
Pubmed	Variation in WNT genes expression in different subtypes of chronic lymphocytic leukemia.	WNT5B WNT3 WNT4	2.49e-07	7	68	3	19863181
Pubmed	Frizzled 1 and frizzled 2 genes function in palate, ventricular septum and neural tube closure: general implications for tissue fusion processes.	WNT5B WNT3 WNT9B WNT4	2.64e-07	28	68	4	20940229
Pubmed	Ectodermal Wnt signaling regulates abdominal myogenesis during ventral body wall development.	WNT5B WNT3 WNT9B WNT4	2.64e-07	28	68	4	24394376
Pubmed	Wnt5a potentiates TGF-β signaling to promote colonic crypt regeneration after tissue injury.	WNT5B WNT3 WNT9B WNT4	3.06e-07	29	68	4	22956684
Pubmed	3D representation of Wnt and Frizzled gene expression patterns in the mouse embryo at embryonic day 11.5 (Ts19).	WNT5B WNT3 WNT9B WNT4	3.06e-07	29	68	4	18364260
Pubmed	Genetic interactions of the androgen and Wnt/beta-catenin pathways for the masculinization of external genitalia.	WNT5B WNT3 WNT9B WNT4	3.52e-07	30	68	4	19282366
Pubmed	Atlas of Wnt and R-spondin gene expression in the developing male mouse lower urogenital tract.	WNT5B WNT3 WNT9B WNT4	3.52e-07	30	68	4	21936019
Pubmed	Expression of all Wnt genes and their secreted antagonists during mouse blastocyst and postimplantation development.	WNT5B WNT3 WNT9B WNT4	3.52e-07	30	68	4	15880404
Pubmed	Overactive Wnt5a signaling disrupts hair follicle polarity during mouse skin development.	WNT5B WNT3 WNT9B WNT4	3.52e-07	30	68	4	36305473
Pubmed	A new nomenclature for int-1 and related genes: the Wnt gene family.	WNT5B WNT3 WNT4	5.95e-07	9	68	3	1846319
Pubmed	WNT5A is transported via lipoprotein particles in the cerebrospinal fluid to regulate hindbrain morphogenesis.	WNT5B WNT3 WNT9B WNT4	6.68e-07	35	68	4	30940800
Pubmed	Comprehensive expression analysis of all Wnt genes and their major secreted antagonists during mouse limb development and cartilage differentiation.	WNT5B WNT3 WNT9B WNT4	6.68e-07	35	68	4	19185060
Pubmed	Integrated analysis of Wnt signalling system component gene expression.	WNT5B WNT3 WNT9B WNT4	8.41e-07	37	68	4	35831952
Pubmed	Mouse Wnt genes exhibit discrete domains of expression in the early embryonic CNS and limb buds.	WNT5B WNT3 WNT4	8.49e-07	10	68	3	8275860
Pubmed	The evolutionarily conserved porcupine gene family is involved in the processing of the Wnt family.	WNT5B WNT3 WNT4	8.49e-07	10	68	3	10866835
Pubmed	Wnt11 promotes cardiomyocyte development by caspase-mediated suppression of canonical Wnt signals.	WNT5B WNT3 WNT9B WNT4	9.38e-07	38	68	4	21041481
Pubmed	Tissue-specific requirements of beta-catenin in external genitalia development.	WNT5B WNT3 WNT9B WNT4	9.38e-07	38	68	4	18635608
Pubmed	Epidermal Wnt controls hair follicle induction by orchestrating dynamic signaling crosstalk between the epidermis and dermis.	WNT5B WNT3 WNT9B WNT4	9.38e-07	38	68	4	23190887
Pubmed	Distinct requirements for cranial ectoderm and mesenchyme-derived wnts in specification and differentiation of osteoblast and dermal progenitors.	WNT5B WNT3 WNT9B WNT4	1.04e-06	39	68	4	24586192
Pubmed	Gene trap screening as an effective approach for identification of Wnt-responsive genes in the mouse embryo.	WNT5B WNT3 WNT4	1.55e-06	12	68	3	15778975
Pubmed	Gpr177 regulates pulmonary vasculature development.	WNT5B WNT3 WNT9B WNT4	1.71e-06	44	68	4	23884445
Pubmed	Homeodomain-mediated beta-catenin-dependent switching events dictate cell-lineage determination.	WNT5B WNT3 WNT9B WNT4	2.24e-06	47	68	4	16678101
Pubmed	Stromal R-spondin orchestrates gastric epithelial stem cells and gland homeostasis.	WNT5B WNT3 WNT9B WNT4	2.24e-06	47	68	4	28813421
Pubmed	Members of the WNT signaling pathways are widely expressed in mouse ovaries, oocytes, and cleavage stage embryos.	WNT5B WNT3 WNT9B WNT4	2.24e-06	47	68	4	18351675
Pubmed	Malformation of Tear Ducts Underlies the Epiphora and Precocious Eyelid Opening in Prickle 1 Mutant Mice: Genetic Implications for Tear Duct Genesis.	WNT5B WNT3 WNT9B WNT4	2.24e-06	47	68	4	33141892
Pubmed	Wnt antagonist SFRP3 inhibits the differentiation of mouse hepatic progenitor cells.	WNT5B WNT3 WNT9B WNT4	2.65e-06	49	68	4	19562671
Pubmed	Expression patterns of Wnt genes in mouse gut development.	WNT5B WNT3 WNT4	3.20e-06	15	68	3	11429295
Pubmed	Expression and estradiol regulation of Wnt genes in the mouse blastocyst identify a candidate pathway for embryo-maternal signaling at implantation.	WNT5B WNT3 WNT4	3.20e-06	15	68	3	15044261
Pubmed	Diabetes risk gene and Wnt effector Tcf7l2/TCF4 controls hepatic response to perinatal and adult metabolic demand.	WNT5B WNT3 WNT9B WNT4	3.37e-06	52	68	4	23260145
Pubmed	Genetic Screening of WNT4 and WNT5B in Two Populations with Deviating Bone Mineral Densities.	WNT5B WNT4	3.77e-06	2	68	2	28078366
Pubmed	Genome-wide association study and mouse expression data identify a highly conserved 32 kb intergenic region between WNT3 and WNT9b as possible susceptibility locus for isolated classic exstrophy of the bladder.	WNT3 WNT9B	3.77e-06	2	68	2	24852367
Pubmed	Expression of Wnt9b and activation of canonical Wnt signaling during midfacial morphogenesis in mice.	WNT3 WNT9B	3.77e-06	2	68	2	16496313
Pubmed	Mesenchymal-transitioned cancer cells instigate the invasion of epithelial cancer cells through secretion of WNT3 and WNT5B.	WNT5B WNT3	3.77e-06	2	68	2	24344732
Pubmed	c-Met and NF-κB-dependent overexpression of Wnt7a and -7b and Pax2 promotes cystogenesis in polycystic kidney disease.	WNT3 WNT9B WNT4	3.93e-06	16	68	3	22677559
Pubmed	Restriction of Wnt signaling in the dorsal otocyst determines semicircular canal formation in the mouse embryo.	WNT3 WNT9B WNT4	5.71e-06	18	68	3	22166339
Pubmed	Coronary Artery Formation Is Driven by Localized Expression of R-spondin3.	WNT5B WNT9B WNT4	6.77e-06	19	68	3	28834739
Pubmed	The canonical Wnt signaling pathway is not involved in renal cyst development in the kidneys of inv mutant mice.	WNT5B WNT9B WNT4	7.96e-06	20	68	3	21248711
Pubmed	Patterns of Wnt pathway activity in the mouse incisor indicate absence of Wnt/beta-catenin signaling in the epithelial stem cells.	WNT5B WNT3 WNT4	9.27e-06	21	68	3	19806668
Pubmed	Wnt/beta-catenin signaling is required for CNS, but not non-CNS, angiogenesis.	WNT5B WNT3 WNT4	9.27e-06	21	68	3	19129494
Pubmed	Characterization of Wnt signaling components and activation of the Wnt canonical pathway in the murine retina.	WNT5B WNT3 WNT4	1.07e-05	22	68	3	12815618
Pubmed	Motor neurons with axial muscle projections specified by Wnt4/5 signaling.	WNT5B WNT3 WNT4	1.07e-05	22	68	3	19285468
Pubmed	Expression of the Wnt inhibitor Dickkopf-1 is required for the induction of neural markers in mouse embryonic stem cells differentiating in response to retinoic acid.	NES WNT3 WNT4	1.07e-05	22	68	3	17064353
Pubmed	An immunohistochemical, enzymatic, and behavioral study of CD157/BST-1 as a neuroregulator.	NES BST1	1.13e-05	3	68	2	28340569
Pubmed	WNT pathways and upper limb anomalies.	WNT3 WNT4	1.13e-05	3	68	2	20709709
Pubmed	Dosage-dependent hedgehog signals integrated with Wnt/beta-catenin signaling regulate external genitalia formation as an appendicular program.	WNT3 WNT9B WNT4	1.23e-05	23	68	3	19906864
Pubmed	Mycn deficiency underlies the development of orofacial clefts in mice and humans.	WNT5B WNT9B WNT4	1.40e-05	24	68	3	34590686
Pubmed	A cluster of three long-range enhancers directs regional Shh expression in the epithelial linings.	WNT5B WNT3 WNT4	1.59e-05	25	68	3	19369396
Pubmed	Wnt signaling controls the timing of oligodendrocyte development in the spinal cord.	WNT3 WNT4	2.25e-05	4	68	2	15950605
Pubmed	Functional consequences of 17q21.31/WNT3-WNT9B amplification in hPSCs with respect to neural differentiation.	WNT3 WNT9B	2.25e-05	4	68	2	25640183
Pubmed	Six2 defines and regulates a multipotent self-renewing nephron progenitor population throughout mammalian kidney development.	WNT9B WNT4	2.25e-05	4	68	2	18682239
Pubmed	Mutational analysis of the WNT gene family in women with Mayer-Rokitansky-Kuster-Hauser syndrome.	WNT9B WNT4	2.25e-05	4	68	2	19171330
Pubmed	Network organization of the human autophagy system.	TRAPPC11 LRPPRC SARS1 ADSL NUP155 USP7 GEMIN4	2.36e-05	437	68	7	20562859
Pubmed	The deubiquitinase USP10 regulates KLF4 stability and suppresses lung tumorigenesis.	USP6 USP7	3.75e-05	5	68	2	31748695
Pubmed	Studies with Wnt genes and nonsyndromic cleft lip and palate.	WNT3 WNT9B	3.75e-05	5	68	2	20890934
Pubmed	Augmented Wnt signaling in a mammalian model of accelerated aging.	WNT3 WNT4	3.75e-05	5	68	2	17690294
Pubmed	Foxf2 in intestinal fibroblasts reduces numbers of Lgr5(+) stem cells and adenoma formation by inhibiting Wnt signaling.	WNT5B WNT3 WNT4	4.47e-05	35	68	3	23376422
Pubmed	GLI2 Modulated by SUFU and SPOP Induces Intestinal Stem Cell Niche Signals in Development and Tumorigenesis.	WNT5B WNT9B WNT4	4.47e-05	35	68	3	31167144
Pubmed	Dual regulation of planar polarization by secreted Wnts and Vangl2 in the developing mouse cochlea.	WNT5B WNT3 WNT4	4.47e-05	35	68	3	32907846
Pubmed	Prediction of the coding sequences of unidentified human genes. XI. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro.	TOX4 NUP155 SACS SYNE1	4.73e-05	101	68	4	9872452
Pubmed	Wnt/Rspondin/β-catenin signals control axonal sorting and lineage progression in Schwann cell development.	WNT5B WNT3 WNT9B	4.87e-05	36	68	3	24151333
Pubmed	Canonical WNT signaling promotes mammary placode development and is essential for initiation of mammary gland morphogenesis.	WNT5B WNT3 WNT4	5.30e-05	37	68	3	15342465
Pubmed	Patterns of Wnt/Fzd/LRP gene expression during embryonic hematopoiesis.	WNT5B WNT3 WNT4	5.30e-05	37	68	3	18800919
Pubmed	Differential regulation of the Wnt gene family during pregnancy and lactation suggests a role in postnatal development of the mammary gland.	WNT5B WNT4	5.62e-05	6	68	2	1373817
Pubmed	The Wnt receptor FZD1 mediates chemoresistance in neuroblastoma through activation of the Wnt/beta-catenin pathway.	WNT3 WNT4	5.62e-05	6	68	2	19421142
Pubmed	Differential expression of human Wnt genes 2, 3, 4, and 7B in human breast cell lines and normal and disease states of human breast tissue.	WNT3 WNT4	5.62e-05	6	68	2	8168088
Pubmed	Wnt/beta-catenin signaling regulates nephron induction during mouse kidney development.	WNT9B WNT4	5.62e-05	6	68	2	17537789
Pubmed	Constructing gene association networks for rheumatoid arthritis using the backward genotype-trait association (BGTA) algorithm.	DLG5 PADI4	5.62e-05	6	68	2	18466472
Pubmed	Cleavage of the Wnt receptor Ryk regulates neuronal differentiation during cortical neurogenesis.	NES WNT3	5.62e-05	6	68	2	19000841
Pubmed	Identification and characterization of the STIM (stromal interaction molecule) gene family: coding for a novel class of transmembrane proteins.	BST1 QDPR	5.62e-05	6	68	2	11463338
Pubmed	Notch pathway activation can replace the requirement for Wnt4 and Wnt9b in mesenchymal-to-epithelial transition of nephron stem cells.	WNT9B WNT4	5.62e-05	6	68	2	21852398
Pubmed	A genome-scale protein interaction profile of Drosophila p53 uncovers additional nodes of the human p53 network.	TRAPPC11 LRPPRC PIWIL1	6.71e-05	40	68	3	20308539
Pubmed	Isolation of two novel WNT genes, WNT14 and WNT15, one of which (WNT15) is closely linked to WNT3 on human chromosome 17q21.	WNT3 WNT9B	7.86e-05	7	68	2	9441749
Pubmed	Variation in WNT genes is associated with non-syndromic cleft lip with or without cleft palate.	WNT3 WNT9B	7.86e-05	7	68	2	18413325
Pubmed	Alterations of the growth characteristics of the fibroblast cell line C3H 10T1/2 by members of the Wnt gene family.	WNT5B WNT4	7.86e-05	7	68	2	8058323
Pubmed	Reconstitution of a frizzled8.Wnt3a.LRP6 signaling complex reveals multiple Wnt and Dkk1 binding sites on LRP6.	WNT5B WNT9B	1.05e-04	8	68	2	20093360
Pubmed	Expression of multiple novel Wnt-1/int-1-related genes during fetal and adult mouse development.	WNT5B WNT4	1.05e-04	8	68	2	2279700
Pubmed	A gene(s) for all-trans-retinoic acid-induced forelimb defects mapped and confirmed to murine chromosome 11.	WNT3 WNT9B	1.05e-04	8	68	2	15781699
Pubmed	Transient expression of MIDC-8 in the normal mouse brain.	NES LY75	1.05e-04	8	68	2	15755524
Pubmed	WNT signaling affects gene expression in the ventral diencephalon and pituitary gland growth.	WNT5B WNT3 WNT4	1.31e-04	50	68	3	18351662
Pubmed	Wnt signaling in heart valve development and osteogenic gene induction.	WNT9B WNT4	1.34e-04	9	68	2	19961844
Pubmed	Pax9's dual roles in modulating Wnt signaling during murine palatogenesis.	WNT3 WNT9B	1.34e-04	9	68	2	32390226
Pubmed	Pax3 and Pax7 are expressed in commissural neurons and restrict ventral neuronal identity in the spinal cord.	WNT3 WNT4	1.34e-04	9	68	2	9858722
Pubmed	Podoplanin and CLEC-2 drive cerebrovascular patterning and integrity during development.	NES SPHK2	1.68e-04	10	68	2	25908104
Pubmed	Alpha N-catenin deficiency causes defects in axon migration and nuclear organization in restricted regions of the mouse brain.	NES ACHE	1.68e-04	10	68	2	16691566
Pubmed	Minor abnormalities of testis development in mice lacking the gene encoding the MAPK signalling component, MAP3K1.	WNT4 MAP3K1	1.68e-04	10	68	2	21559298
Pubmed	Expression patterns of Wnt genes during development of an anterior part of the chicken eye.	WNT5B WNT9B	1.68e-04	10	68	2	16258938
Pubmed	FGF8 induces chemokinesis and regulates condensation of mouse nephron progenitor cells.	WNT9B WNT4	1.68e-04	10	68	2	36205075
Pubmed	Nonsyndromic Disorders of Testicular Development Overview	WNT4 MAP3K1	1.68e-04	10	68	2	20301714
Pubmed	Trps1 functions downstream of Bmp7 in kidney development.	WNT9B WNT4	1.68e-04	10	68	2	19820125
Interaction	TNRC6A interactions	NES DLG5 NUP155 FAM120C RC3H1 MED14 TRIM37 CNOT4	3.59e-06	280	66	8	int:TNRC6A
Interaction	EYA4 interactions	ADSL NUP155 RC3H1 USP7 SCO1 C15orf39 CNOT4	1.44e-05	243	66	7	int:EYA4
Interaction	PORCN interactions	WNT5B WNT3 WNT4	1.82e-05	16	66	3	int:PORCN
Interaction	LY75 interactions	USP7 LY75	3.16e-05	3	66	2	int:LY75
Cytoband	17p13	USP6 GEMIN4	1.18e-03	34	68	2	17p13
Cytoband	7q22	ACHE CNOT4	1.47e-03	38	68	2	7q22
Cytoband	Ensembl 112 genes in cytogenetic band chr17p13	USP6 GEMIN4 SCO1 SAT2	1.77e-03	346	68	4	chr17p13
GeneFamily	Wnt family\|Endogenous ligands	WNT5B WNT3 WNT9B WNT4	1.65e-07	19	48	4	360
Coexpression	GSE360_T_GONDII_VS_B_MALAYI_HIGH_DOSE_MAC_DN	SPHK2 FCGBP BST1 PARP3 MED14 MUC6	1.21e-05	199	67	6	M5255
Disease	cognitive function measurement, self reported educational attainment	LRPPRC WNT3 CACNA1I WNT4 TRIM37	1.29e-03	355	67	5	EFO_0004784, EFO_0008354
Disease	handedness	WNT3 SCO1 METAP2	1.83e-03	106	67	3	EFO_0009902

Protein segments in the cluster

Peptide	Gene	Start	Entry
TVDWNSKRRNLRFFC	nan	316	A8MVM7
VRRGLRAQACAFWNR	ACHE	551	P22303
RVADFLSWCRQKNDS	BST1	136	Q10588
EQRVAQASLARWRSC	C1orf167	1076	Q5SNV9
WTIERSNQEHCFRAR	CFAP43	181	Q8NDM7
ALGSRCVQAFRARNW	QDPR	21	P09417
SRFRCRGVDANRNWK	CPA6	261	Q8N4T0
SNLWAAVRARGCQFL	RC3H1	181	Q5TC82
FRKNWRALCNSERTT	PARPBP	16	Q9NWS1
QLLQDSNRFFTCWNR	PARP3	86	Q9Y6F1
ANQRVSIDNWCRRDK	APLP2	106	Q06481
REHNSFVERCIDWNR	PADI4	536	Q9UM07
AFRRSWAERKCSVIN	MUC6	1051	Q6W4X9
LWCNSTVHDDCRRRF	DGKK	431	Q5KSL6
INENFGTLAFCRRWL	METAP2	406	P50579
ACSWFQNLRDRFRSQ	LONRF1	691	Q17RB8
WKRQFSICRDENDRL	HOMER2	211	Q9NSB8
NTIRKAWNDRDNRCD	KIF26B	171	Q2KJY2
RARWRLVAATAAFCL	EDEM3	16	Q9BZQ6
RALCSAAQAAWRENF	MTG1	6	Q9BT17
ATWAERLRALNNCLS	OR51Q1	231	Q8NH59
FRAALETCERAWQSL	PEX26	51	Q7Z412
ADVAKCRRDWAFQER	DLG5	516	Q8TDM6
RNRRAVEAEKCARAW	NES	111	P48681
VRKRNWEEAERFCQA	LY75	666	O60449
IRARSARLQWFCDRC	LRPPRC	916	P42704
WQARRRFLQARQAAC	IQCF6	56	A8MYZ5
EDEQSRTCWLAAFRL	GRB7	321	Q14451
AWNERAVNRVSAIRF	LRRC1	446	Q9BTT6
CDREVSAWATRAFFR	NUP155	561	O75694
LDCTFRLQGRNNRTW	MED14	706	O60244
LRCAAAESWARLAQV	HEATR5A	866	Q86XA9
SWRQNEQRRQGLFCD	KLHL11	81	Q9NVR0
AACQAAGAQLREWRR	FCGBP	3516	Q9Y6R7
WAGLLRNRCFLEENF	CACNA1I	231	Q9P0X4
AEWGRRCQAERQTAQ	FAM120C	181	Q9NX05
EARQRNWQSCDRFRS	BRWD1	1061	Q9NSI6
CLARRWNQLDRSDVA	MAP6D1	11	Q9H9H5
QACVRWFRQALQGRE	FPGS	386	Q05932
LRQFCARQAEAWRAS	SCO1	41	O75880
EARRWLRQARANFSA	SACS	4446	Q9NZJ4
GCSQFRLAVLDWNQR	SAT2	121	Q96F10
DRACASSVCRRWNEV	FBXL21P	61	Q9UKT6
CLFSRNWNVREMALR	MAP3K1	571	Q13233
TRWFSRCIFQDRGQE	PIWIL1	656	Q96J94
DVESRDRQARCIWFL	POLR1E	266	Q9GZS1
SEWRRCRFRADNLNK	SARS1	41	P49591
CFSCIRRWLTEQRAQ	TRIM37	36	O94972
EFLVTDNSRNWRFRA	PPP4R1	746	Q8TF05
CDSIQQATRNLDRRW	SYNE1	7966	Q8NF91
WFERTLDDSANRRIC	ADSL	326	P30566
RALATLQSQWEACRA	PLA2G3	106	Q9NZ20
CQRRSQLNNRWASFH	SPTBN5	2336	Q9NRC6
QWRDCVRRQLGDFDT	C15orf39	916	Q6ZRI6
QICRFCWHRIRTDEN	CNOT4	36	O95628
AVHRAVWDAFCANRR	TRAPPC11	31	Q7Z392
VVNDRSWKVFNERCR	MIX23	121	Q4VC31
NRAEAQRWATALTCL	SPHK2	146	Q9NRA0
VFRAFRRANARCFWN	STOX1	36	Q6ZVD7
RRANARCFWNARLAR	STOX1	41	Q6ZVD7
RCFWNARLARAASRL	STOX1	46	Q6ZVD7
QHQFRGRRWNCTTID	WNT3	81	P56703
QFRQRRWNCSTADNA	WNT5B	86	Q9H1J7
QTSRAWFIDRARQAR	UBE3B	6	Q7Z3V4
QQCDRRFRWSSDLNK	ZNF75D	396	P51815
QFRNRRWNCSTLDSL	WNT4	81	P56705
FQFRHERWNCSLEGR	WNT9B	91	O14905
RRSFKCIWLNSQFRE	USP7	891	Q93009
RCGLWARLRNQFFDT	USP6	316	P35125
CRDVFLAWVASRNSN	TOX4	601	O94842
EWVACLGSNRALFRQ	GEMIN4	436	P57678