Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	mRNA 3'-UTR AU-rich region binding	ZFP36L1 ZFP36L2	1.83e-04	29	14	2	GO:0035925
GeneOntologyMolecularFunction	receptor ligand activity	INHA BMP4 RELN	5.94e-03	547	14	3	GO:0048018
GeneOntologyMolecularFunction	signaling receptor activator activity	INHA BMP4 RELN	6.15e-03	554	14	3	GO:0030546
GeneOntologyMolecularFunction	growth factor activity	INHA BMP4	6.34e-03	173	14	2	GO:0008083
GeneOntologyMolecularFunction	extracellular matrix structural constituent	LAMA5 RELN	7.45e-03	188	14	2	GO:0005201
GeneOntologyMolecularFunction	signaling receptor regulator activity	INHA BMP4 RELN	8.25e-03	616	14	3	GO:0030545
GeneOntologyMolecularFunction	serine-type peptidase activity	C1S RELN	8.97e-03	207	14	2	GO:0008236
GeneOntologyMolecularFunction	serine hydrolase activity	C1S RELN	9.39e-03	212	14	2	GO:0017171
GeneOntologyBiologicalProcess	regulation of B cell differentiation	ZFP36L1 ZFP36L2 INHA	3.71e-06	46	14	3	GO:0045577
GeneOntologyBiologicalProcess	cellular response to glucocorticoid stimulus	ZFP36L1 ZFP36L2 BMP4	1.22e-05	68	14	3	GO:0071385
GeneOntologyBiologicalProcess	cellular response to corticosteroid stimulus	ZFP36L1 ZFP36L2 BMP4	2.06e-05	81	14	3	GO:0071384
GeneOntologyBiologicalProcess	regulation of lymphocyte differentiation	ZFP36L1 ZFP36L2 INHA BMP4	2.45e-05	266	14	4	GO:0045619
GeneOntologyBiologicalProcess	myeloid leukocyte differentiation	P2RX5 ZFP36L1 INHA BMP4	4.56e-05	312	14	4	GO:0002573
GeneOntologyBiologicalProcess	positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay	ZFP36L1 ZFP36L2	5.11e-05	16	14	2	GO:1900153
GeneOntologyBiologicalProcess	T cell differentiation in thymus	ZFP36L1 ZFP36L2 BMP4	5.73e-05	114	14	3	GO:0033077
GeneOntologyBiologicalProcess	segmentation	LAMA5 BMP4 CRB2	7.18e-05	123	14	3	GO:0035282
GeneOntologyBiologicalProcess	3'-UTR-mediated mRNA destabilization	ZFP36L1 ZFP36L2	7.27e-05	19	14	2	GO:0061158
GeneOntologyBiologicalProcess	positive regulation of calcium ion transport into cytosol	P2RX5 BMP4	8.92e-05	21	14	2	GO:0010524
GeneOntologyBiologicalProcess	mesenchyme development	ZFP36L1 LAMA5 BMP4 CRB2	9.03e-05	372	14	4	GO:0060485
GeneOntologyBiologicalProcess	leukocyte differentiation	P2RX5 ZFP36L1 ZFP36L2 INHA BMP4	1.21e-04	789	14	5	GO:0002521
GeneOntologyBiologicalProcess	mesoderm development	ZFP36L1 BMP4 CRB2	1.48e-04	157	14	3	GO:0007498
GeneOntologyBiologicalProcess	regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay	ZFP36L1 ZFP36L2	1.49e-04	27	14	2	GO:1900151
GeneOntologyBiologicalProcess	regulation of calcium ion transport into cytosol	P2RX5 BMP4	1.49e-04	27	14	2	GO:0010522
GeneOntologyBiologicalProcess	regulation of leukocyte differentiation	ZFP36L1 ZFP36L2 INHA BMP4	1.57e-04	429	14	4	GO:1902105
GeneOntologyBiologicalProcess	response to glucocorticoid	ZFP36L1 ZFP36L2 BMP4	1.57e-04	160	14	3	GO:0051384
GeneOntologyBiologicalProcess	regulation of B cell activation	ZFP36L1 ZFP36L2 INHA	1.65e-04	163	14	3	GO:0050864
GeneOntologyBiologicalProcess	erythrocyte differentiation	ZFP36L1 INHA BMP4	2.07e-04	176	14	3	GO:0030218
GeneOntologyBiologicalProcess	negative regulation of cell cycle	ZFP36L1 ZFP36L2 INHA BMP4	2.12e-04	464	14	4	GO:0045786
GeneOntologyBiologicalProcess	regionalization	LAMA5 BMP4 RELN CRB2	2.37e-04	478	14	4	GO:0003002
GeneOntologyBiologicalProcess	response to corticosteroid	ZFP36L1 ZFP36L2 BMP4	2.40e-04	185	14	3	GO:0031960
GeneOntologyBiologicalProcess	monocyte differentiation	ZFP36L1 BMP4	2.51e-04	35	14	2	GO:0030224
GeneOntologyBiologicalProcess	blastoderm segmentation	LAMA5 BMP4	2.51e-04	35	14	2	GO:0007350
GeneOntologyBiologicalProcess	erythrocyte homeostasis	ZFP36L1 INHA BMP4	2.60e-04	190	14	3	GO:0034101
GeneOntologyBiologicalProcess	positive regulation of monoatomic ion transmembrane transport	P2RX5 BMP4 RELN	2.68e-04	192	14	3	GO:0034767
GeneOntologyBiologicalProcess	B cell differentiation	ZFP36L1 ZFP36L2 INHA	3.07e-04	201	14	3	GO:0030183
GeneOntologyBiologicalProcess	pattern specification process	LAMA5 BMP4 RELN CRB2	3.41e-04	526	14	4	GO:0007389
GeneOntologyBiologicalProcess	positive regulation of BMP signaling pathway	BMP4 CRB2	3.63e-04	42	14	2	GO:0030513
GeneOntologyBiologicalProcess	calcium ion transport into cytosol	P2RX5 BMP4	3.63e-04	42	14	2	GO:0060402
GeneOntologyBiologicalProcess	lymphocyte differentiation	ZFP36L1 ZFP36L2 INHA BMP4	3.69e-04	537	14	4	GO:0030098
GeneOntologyBiologicalProcess	regulation of hemopoiesis	ZFP36L1 ZFP36L2 INHA BMP4	3.77e-04	540	14	4	GO:1903706
GeneOntologyBiologicalProcess	myeloid cell differentiation	P2RX5 ZFP36L1 INHA BMP4	4.27e-04	558	14	4	GO:0030099
GeneOntologyBiologicalProcess	cellular response to epidermal growth factor stimulus	ZFP36L1 ZFP36L2	4.94e-04	49	14	2	GO:0071364
GeneOntologyBiologicalProcess	cellular response to steroid hormone stimulus	ZFP36L1 ZFP36L2 BMP4	5.09e-04	239	14	3	GO:0071383
GeneOntologyBiologicalProcess	myeloid cell homeostasis	ZFP36L1 INHA BMP4	5.15e-04	240	14	3	GO:0002262
GeneOntologyBiologicalProcess	regulation of transmembrane transport	P2RX5 BMP4 RELN SEPTIN2	5.24e-04	589	14	4	GO:0034762
GeneOntologyBiologicalProcess	regulation of cell development	ZFP36L1 ZFP36L2 INHA BMP4 RELN	5.59e-04	1095	14	5	GO:0060284
GeneOntologyBiologicalProcess	response to epidermal growth factor	ZFP36L1 ZFP36L2	6.00e-04	54	14	2	GO:0070849
GeneOntologyBiologicalProcess	regulation of lymphocyte activation	ZFP36L1 ZFP36L2 INHA BMP4	6.13e-04	614	14	4	GO:0051249
GeneOntologyBiologicalProcess	skeletal system development	P2RX5 INHA LAMA5 BMP4	6.17e-04	615	14	4	GO:0001501
GeneOntologyBiologicalProcess	positive regulation of monoatomic ion transport	P2RX5 BMP4 RELN	6.95e-04	266	14	3	GO:0043270
GeneOntologyBiologicalProcess	mononuclear cell differentiation	ZFP36L1 ZFP36L2 INHA BMP4	7.17e-04	640	14	4	GO:1903131
GeneOntologyBiologicalProcess	positive regulation of transmembrane transport	P2RX5 BMP4 RELN	7.49e-04	273	14	3	GO:0034764
GeneOntologyBiologicalProcess	neural crest cell migration	LAMA5 BMP4	7.90e-04	62	14	2	GO:0001755
GeneOntologyBiologicalProcess	positive regulation of epithelial to mesenchymal transition	BMP4 CRB2	8.16e-04	63	14	2	GO:0010718
GeneOntologyBiologicalProcess	regulation of epidermal cell differentiation	ZFP36L1 BMP4	8.16e-04	63	14	2	GO:0045604
GeneOntologyBiologicalProcess	negative regulation of mitotic cell cycle	ZFP36L1 ZFP36L2 BMP4	8.23e-04	282	14	3	GO:0045930
GeneOntologyBiologicalProcess	mesenchymal cell migration	LAMA5 BMP4	8.42e-04	64	14	2	GO:0090497
GeneOntologyBiologicalProcess	nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay	ZFP36L1 ZFP36L2	8.68e-04	65	14	2	GO:0000288
GeneOntologyBiologicalProcess	p38MAPK cascade	ZFP36L1 BMP4	9.22e-04	67	14	2	GO:0038066
GeneOntologyBiologicalProcess	hemopoiesis	P2RX5 ZFP36L1 ZFP36L2 INHA BMP4	9.27e-04	1223	14	5	GO:0030097
GeneOntologyBiologicalProcess	mesenchymal cell differentiation	LAMA5 BMP4 CRB2	9.47e-04	296	14	3	GO:0048762
GeneOntologyBiologicalProcess	branching involved in ureteric bud morphogenesis	LAMA5 BMP4	9.50e-04	68	14	2	GO:0001658
GeneOntologyBiologicalProcess	regulation of leukocyte activation	ZFP36L1 ZFP36L2 INHA BMP4	9.71e-04	694	14	4	GO:0002694
GeneOntologyBiologicalProcess	negative regulation of lymphocyte differentiation	INHA BMP4	1.01e-03	70	14	2	GO:0045620
GeneOntologyBiologicalProcess	protein localization to membrane	LAMA5 FRMD8 RELN FRMD8P1	1.03e-03	705	14	4	GO:0072657
GeneOntologyBiologicalProcess	regulation of epidermis development	ZFP36L1 BMP4	1.04e-03	71	14	2	GO:0045682
GeneOntologyBiologicalProcess	stem cell differentiation	ZFP36L2 LAMA5 BMP4	1.04e-03	306	14	3	GO:0048863
GeneOntologyBiologicalProcess	embryonic morphogenesis	ZFP36L1 LAMA5 BMP4 CRB2	1.07e-03	713	14	4	GO:0048598
GeneOntologyBiologicalProcess	ureteric bud morphogenesis	LAMA5 BMP4	1.12e-03	74	14	2	GO:0060675
GeneOntologyBiologicalProcess	macrophage differentiation	INHA BMP4	1.22e-03	77	14	2	GO:0030225
GeneOntologyBiologicalProcess	protein localization to plasma membrane	LAMA5 FRMD8 FRMD8P1	1.23e-03	324	14	3	GO:0072659
GeneOntologyBiologicalProcess	mesonephric tubule morphogenesis	LAMA5 BMP4	1.25e-03	78	14	2	GO:0072171
GeneOntologyBiologicalProcess	regulation of cell activation	ZFP36L1 ZFP36L2 INHA BMP4	1.34e-03	756	14	4	GO:0050865
GeneOntologyBiologicalProcess	mesoderm formation	BMP4 CRB2	1.38e-03	82	14	2	GO:0001707
GeneOntologyBiologicalProcess	B cell activation	ZFP36L1 ZFP36L2 INHA	1.42e-03	341	14	3	GO:0042113
GeneOntologyBiologicalProcess	mesoderm morphogenesis	BMP4 CRB2	1.51e-03	86	14	2	GO:0048332
GeneOntologyBiologicalProcess	ovarian follicle development	INHA BMP4	1.55e-03	87	14	2	GO:0001541
GeneOntologyBiologicalProcess	nephron tubule morphogenesis	LAMA5 BMP4	1.55e-03	87	14	2	GO:0072078
GeneOntologyBiologicalProcess	endoderm development	ZFP36L1 BMP4	1.58e-03	88	14	2	GO:0007492
GeneOntologyBiologicalProcess	neural crest cell development	LAMA5 BMP4	1.62e-03	89	14	2	GO:0014032
GeneOntologyBiologicalProcess	nephron epithelium morphogenesis	LAMA5 BMP4	1.62e-03	89	14	2	GO:0072088
GeneOntologyBiologicalProcess	localization within membrane	LAMA5 FRMD8 RELN FRMD8P1	1.63e-03	798	14	4	GO:0051668
GeneOntologyBiologicalProcess	negative regulation of cell cycle process	ZFP36L1 ZFP36L2 BMP4	1.69e-03	362	14	3	GO:0010948
GeneOntologyBiologicalProcess	embryonic pattern specification	LAMA5 BMP4	1.69e-03	91	14	2	GO:0009880
GeneOntologyBiologicalProcess	nephron morphogenesis	LAMA5 BMP4	1.69e-03	91	14	2	GO:0072028
GeneOntologyCellularComponent	centriolar satellite	FRMD8 FRMD8P1	3.23e-03	128	14	2	GO:0034451
GeneOntologyCellularComponent	photoreceptor cell cilium	INHA SEPTIN2	3.79e-03	139	14	2	GO:0097733
GeneOntologyCellularComponent	9+0 non-motile cilium	INHA SEPTIN2	4.57e-03	153	14	2	GO:0097731
GeneOntologyCellularComponent	non-motile cilium	INHA SEPTIN2	7.39e-03	196	14	2	GO:0097730
GeneOntologyCellularComponent	axoneme	CFAP61 SEPTIN2	8.21e-03	207	14	2	GO:0005930
GeneOntologyCellularComponent	ciliary plasm	CFAP61 SEPTIN2	8.29e-03	208	14	2	GO:0097014
GeneOntologyCellularComponent	sperm flagellum	CFAP61 SEPTIN2	8.75e-03	214	14	2	GO:0036126
GeneOntologyCellularComponent	9+2 motile cilium	CFAP61 SEPTIN2	1.07e-02	238	14	2	GO:0097729
MousePheno	abnormal visceral yolk sac blood island morphology	ZFP36L1 BMP4 CRB2	2.36e-06	32	12	3	MP:0011204
MousePheno	abnormal visceral yolk sac mesenchyme morphology	ZFP36L1 BMP4 CRB2	3.40e-06	36	12	3	MP:0020516
MousePheno	small allantois	BMP4 CRB2	8.05e-05	16	12	2	MP:0004559
MousePheno	abnormal extraembryonic tissue physiology	ZFP36L1 ZFP36L2 BMP4 CRB2	1.54e-04	345	12	4	MP:0004264
MousePheno	pancytopenia	ZFP36L2 INHA	1.55e-04	22	12	2	MP:0005152
MousePheno	abnormal amniotic cavity morphology	BMP4 CRB2	2.00e-04	25	12	2	MP:0011199
MousePheno	abnormal neural tube closure	ZFP36L1 LAMA5 BMP4 CRB2	2.19e-04	378	12	4	MP:0003720
MousePheno	abnormal foregut morphology	BMP4 CRB2	2.90e-04	30	12	2	MP:0000474
Domain	Tis11B_N	ZFP36L1 ZFP36L2	4.47e-07	2	13	2	PF04553
Domain	Tis11B_N	ZFP36L1 ZFP36L2	4.47e-07	2	13	2	IPR007635
Domain	EGF-like_dom	LAMA5 C1S RELN CRB2	2.01e-05	249	13	4	IPR000742
Domain	EGF_1	LAMA5 C1S RELN CRB2	2.20e-05	255	13	4	PS00022
Domain	EGF-like_CS	LAMA5 C1S RELN CRB2	2.41e-05	261	13	4	IPR013032
Domain	EGF_2	LAMA5 C1S RELN CRB2	2.56e-05	265	13	4	PS01186
Domain	TGF-beta-rel	INHA BMP4	2.19e-04	32	13	2	IPR015615
Domain	TGFb_CS	INHA BMP4	2.19e-04	32	13	2	IPR017948
Domain	TGFB	INHA BMP4	2.94e-04	37	13	2	SM00204
Domain	TGF-b_C	INHA BMP4	2.94e-04	37	13	2	IPR001839
Domain	TGF_BETA_2	INHA BMP4	2.94e-04	37	13	2	PS51362
Domain	TGF_BETA_1	INHA BMP4	2.94e-04	37	13	2	PS00250
Domain	TGF_beta	INHA BMP4	2.94e-04	37	13	2	PF00019
Domain	LAM_G_DOMAIN	LAMA5 CRB2	3.10e-04	38	13	2	PS50025
Domain	-	ZFP36L1 ZFP36L2	3.44e-04	40	13	2	4.10.1000.10
Domain	Laminin_G_2	LAMA5 CRB2	3.44e-04	40	13	2	PF02210
Domain	LamG	LAMA5 CRB2	4.16e-04	44	13	2	SM00282
Domain	ZnF_C3H1	ZFP36L1 ZFP36L2	4.95e-04	48	13	2	SM00356
Domain	EGF	LAMA5 RELN CRB2	5.12e-04	235	13	3	SM00181
Domain	EGF_3	C1S RELN CRB2	5.12e-04	235	13	3	PS50026
Domain	zf-CCCH	ZFP36L1 ZFP36L2	5.16e-04	49	13	2	PF00642
Domain	Laminin_G	LAMA5 CRB2	7.23e-04	58	13	2	IPR001791
Domain	Znf_CCCH	ZFP36L1 ZFP36L2	7.23e-04	58	13	2	IPR000571
Domain	ZF_C3H1	ZFP36L1 ZFP36L2	7.23e-04	58	13	2	PS50103
Domain	-	INHA BMP4	9.64e-04	67	13	2	2.10.90.10
Domain	Cystine-knot_cytokine	INHA BMP4	9.64e-04	67	13	2	IPR029034
Domain	-	LAMA5 CRB2	1.93e-03	95	13	2	2.60.120.200
Domain	EGF_Ca-bd_CS	C1S CRB2	2.01e-03	97	13	2	IPR018097
Domain	EGF_CA	C1S CRB2	2.09e-03	99	13	2	PS01187
Domain	ASX_HYDROXYL	C1S CRB2	2.13e-03	100	13	2	PS00010
Domain	EGF-type_Asp/Asn_hydroxyl_site	C1S CRB2	2.39e-03	106	13	2	IPR000152
Domain	EGF_CA	C1S CRB2	3.15e-03	122	13	2	SM00179
Domain	EGF-like_Ca-bd_dom	C1S CRB2	3.25e-03	124	13	2	IPR001881
Domain	EGF	C1S CRB2	3.35e-03	126	13	2	PF00008
Domain	ConA-like_dom	LAMA5 CRB2	9.80e-03	219	13	2	IPR013320
Pubmed	Characterization of DeltaN-Zfp36l2 mutant associated with arrest of early embryonic development and female infertility.	ZFP36L1 ZFP36L2	1.50e-07	2	14	2	22367205
Pubmed	Deletion of the RNA-binding proteins ZFP36L1 and ZFP36L2 leads to perturbed thymic development and T lymphoblastic leukemia.	ZFP36L1 ZFP36L2	1.50e-07	2	14	2	20622884
Pubmed	ZFP36L1 and ZFP36L2 inhibit cell proliferation in a cyclin D-dependent and p53-independent manner.	ZFP36L1 ZFP36L2	1.50e-07	2	14	2	29426877
Pubmed	Polymorphisms in the genes encoding members of the tristetraprolin family of human tandem CCCH zinc finger proteins.	ZFP36L1 ZFP36L2	4.51e-07	3	14	2	14604009
Pubmed	The ZFP36 family of RNA binding proteins regulates homeostatic and autoreactive T cell responses.	ZFP36L1 ZFP36L2	4.51e-07	3	14	2	36269839
Pubmed	The roles of TTP and BRF proteins in regulated mRNA decay.	ZFP36L1 ZFP36L2	4.51e-07	3	14	2	21278925
Pubmed	Zfp36l3, a rodent X chromosome gene encoding a placenta-specific member of the Tristetraprolin family of CCCH tandem zinc finger proteins.	ZFP36L1 ZFP36L2	4.51e-07	3	14	2	15814898
Pubmed	The RNA-binding proteins Zfp36l1 and Zfp36l2 act redundantly in myogenesis.	ZFP36L1 ZFP36L2	4.51e-07	3	14	2	30526691
Pubmed	The TIS11 primary response gene is a member of a gene family that encodes proteins with a highly conserved sequence containing an unusual Cys-His repeat.	ZFP36L1 ZFP36L2	4.51e-07	3	14	2	1996120
Pubmed	FRMD8 targets both CDK4 activation and RB degradation to suppress colon cancer growth.	FRMD8 FRMD8P1	4.51e-07	3	14	2	37527040
Pubmed	The ADAM17 sheddase complex regulator iTAP/Frmd8 modulates inflammation and tumor growth.	FRMD8 FRMD8P1	4.51e-07	3	14	2	36720499
Pubmed	The RNA-Binding Proteins Zfp36l1 and Zfp36l2 Enforce the Thymic β-Selection Checkpoint by Limiting DNA Damage Response Signaling and Cell Cycle Progression.	ZFP36L1 ZFP36L2	4.51e-07	3	14	2	27566829
Pubmed	ZFP36 Family Members Regulate the Proinflammatory Features of Psoriatic Dermal Fibroblasts.	ZFP36L1 ZFP36L2	4.51e-07	3	14	2	34333017
Pubmed	Functional analysis of ZFP36 proteins in keratinocytes.	ZFP36L1 ZFP36L2	4.51e-07	3	14	2	27182009
Pubmed	ZFP36L1 and ZFP36L2 control LDLR mRNA stability via the ERK-RSK pathway.	ZFP36L1 ZFP36L2	9.02e-07	4	14	2	25106868
Pubmed	RNA-binding proteins ZFP36L1 and ZFP36L2 promote cell quiescence.	ZFP36L1 ZFP36L2	9.02e-07	4	14	2	27102483
Pubmed	Synergistic roles of tristetraprolin family members in myeloid cells in the control of inflammation.	ZFP36L1 ZFP36L2	9.02e-07	4	14	2	37903626
Pubmed	Multiple tristetraprolin sequence domains required to induce apoptosis and modulate responses to TNFalpha through distinct pathways.	ZFP36L1 ZFP36L2	9.02e-07	4	14	2	12082611
Pubmed	ZFP36L1 is regulated by growth factors and cytokines in keratinocytes and influences their VEGF production.	ZFP36L1 ZFP36L2	9.02e-07	4	14	2	20166898
Pubmed	Members of the tristetraprolin family of tandem CCCH zinc finger proteins exhibit CRM1-dependent nucleocytoplasmic shuttling.	ZFP36L1 ZFP36L2	9.02e-07	4	14	2	11796723
Pubmed	Spatiotemporal regulation of GLI target genes in the mammalian limb bud.	INHA FRMD8 BMP4 FRMD8P1	1.16e-06	207	14	4	26238476
Pubmed	FRMD8 promotes inflammatory and growth factor signalling by stabilising the iRhom/ADAM17 sheddase complex.	FRMD8 FRMD8P1	1.50e-06	5	14	2	29897336
Pubmed	iTAP, a novel iRhom interactor, controls TNF secretion by policing the stability of iRhom/TACE.	FRMD8 FRMD8P1	1.50e-06	5	14	2	29897333
Pubmed	Differential expression and functional analysis of the tristetraprolin family during early differentiation of 3T3-L1 preadipocytes.	ZFP36L1 ZFP36L2	1.50e-06	5	14	2	22701344
Pubmed	Endothelial Jagged1 levels and distribution are post-transcriptionally controlled by ZFP36 decay proteins.	ZFP36L1 ZFP36L2	1.50e-06	5	14	2	38157296
Pubmed	Brf1 posttranscriptionally regulates pluripotency and differentiation responses downstream of Erk MAP kinase.	ZFP36L1 ZFP36L2	1.50e-06	5	14	2	24733888
Pubmed	Deficiency of the placenta- and yolk sac-specific tristetraprolin family member ZFP36L3 identifies likely mRNA targets and an unexpected link to placental iron metabolism.	ZFP36L1 ZFP36L2	1.50e-06	5	14	2	26952984
Pubmed	Destabilization of vascular endothelial growth factor mRNA by the zinc-finger protein TIS11b.	ZFP36L1 ZFP36L2	1.50e-06	5	14	2	15467755
Pubmed	Blood-induced bone loss in murine hemophilic arthropathy is prevented by blocking the iRhom2/ADAM17/TNF-α pathway.	FRMD8 FRMD8P1	2.25e-06	6	14	2	29776906
Pubmed	Maintenance of the marginal-zone B cell compartment specifically requires the RNA-binding protein ZFP36L1.	ZFP36L1 ZFP36L2	2.25e-06	6	14	2	28394372
Pubmed	Loss of Emx2 function leads to ectopic expression of Wnt1 in the developing telencephalon and cortical dysplasia.	BMP4 RELN	5.41e-06	9	14	2	12668639
Pubmed	Patterning of the dorsal telencephalon and cerebral cortex by a roof plate-Lhx2 pathway.	BMP4 RELN	9.91e-06	12	14	2	11719201
Pubmed	Deficiency in Crumbs homolog 2 (Crb2) affects gastrulation and results in embryonic lethality in mice.	BMP4 CRB2	9.91e-06	12	14	2	22072575
Pubmed	Smooth muscle-endothelial cell communication activates Reelin signaling and regulates lymphatic vessel formation.	LAMA5 RELN	1.37e-05	14	14	2	22665518
Pubmed	Regulation of the ovarian reserve by members of the transforming growth factor beta family.	INHA BMP4	1.37e-05	14	14	2	22847922
Pubmed	The role of Foxg1 and dorsal midline signaling in the generation of Cajal-Retzius subtypes.	BMP4 RELN	1.58e-05	15	14	2	17928452
Pubmed	Bmp7 regulates the survival, proliferation, and neurogenic properties of neural progenitor cells during corticogenesis in the mouse.	BMP4 RELN	2.04e-05	17	14	2	22461901
Pubmed	Crumbs 2 prevents cortical abnormalities in mouse dorsal telencephalon.	RELN CRB2	2.85e-05	20	14	2	26802325
Pubmed	Early dorsomedial tissue interactions regulate gyrification of distal neocortex.	BMP4 RELN	3.15e-05	21	14	2	31729356
Pubmed	The apical complex couples cell fate and cell survival to cerebral cortical development.	RELN CRB2	3.46e-05	22	14	2	20399730
Pubmed	Patterning the dorsal telencephalon: a role for sonic hedgehog?	BMP4 RELN	4.49e-05	25	14	2	17959802
Pubmed	The ciliogenic transcription factor RFX3 regulates early midline distribution of guidepost neurons required for corpus callosum development.	BMP4 RELN	4.49e-05	25	14	2	22479201
Pubmed	Lamination of the cerebral cortex is disturbed in Gli3 mutant mice.	BMP4 RELN	5.25e-05	27	14	2	18448089
Pubmed	Lateral Thalamic Eminence: A Novel Origin for mGluR1/Lot Cells.	BMP4 RELN	5.65e-05	28	14	2	27178193
Pubmed	Lats1/2 inactivation reveals Hippo function in alveolar type I cell differentiation during lung transition to air breathing.	LAMA5 BMP4	6.95e-05	31	14	2	30305289
Pubmed	β-Catenin gain of function in muscles impairs neuromuscular junction formation.	BMP4 RELN	8.38e-05	34	14	2	22627288
Pubmed	Laminin-511 is an epithelial message promoting dermal papilla development and function during early hair morphogenesis.	LAMA5 BMP4	8.89e-05	35	14	2	18676816
Pubmed	Adamts18 Deficiency Causes Spontaneous SMG Fibrogenesis in Adult Mice.	LAMA5 BMP4	9.94e-05	37	14	2	34323105
Pubmed	Epicardial cell shape and maturation are regulated by Wt1 via transcriptional control of Bmp4.	BMP4 RELN	1.05e-04	38	14	2	31624071
Pubmed	Hes genes and neurogenin regulate non-neural versus neural fate specification in the dorsal telencephalic midline.	BMP4 RELN	1.05e-04	38	14	2	18579678
Pubmed	Pbx Regulates Patterning of the Cerebral Cortex in Progenitors and Postmitotic Neurons.	BMP4 RELN	1.16e-04	40	14	2	26671461
Pubmed	Thyroid follicle development requires Smad1/5- and endothelial cell-dependent basement membrane assembly.	LAMA5 BMP4	1.16e-04	40	14	2	27068110
Pubmed	Genetic evidence that SOST inhibits WNT signaling in the limb.	INHA BMP4	1.47e-04	45	14	2	20359476
Pubmed	Sox9 plays multiple roles in the lung epithelium during branching morphogenesis.	LAMA5 BMP4	1.82e-04	50	14	2	24191021
Pubmed	The doublesex homolog Dmrt5 is required for the development of the caudomedial cerebral cortex in mammals.	BMP4 RELN	2.90e-04	63	14	2	22923088
Pubmed	Expression and misexpression of members of the FGF and TGFbeta families of growth factors in the developing mouse pancreas.	INHA BMP4	3.18e-04	66	14	2	12666204
Interaction	FRMD8P1 interactions	FRMD8 FRMD8P1	2.69e-06	4	14	2	int:FRMD8P1
Interaction	C1R interactions	ZFP36L2 C1S	4.68e-05	15	14	2	int:C1R
Interaction	FRMD8 interactions	FRMD8 FRMD8P1	7.61e-05	19	14	2	int:FRMD8
Interaction	FST interactions	INHA BMP4	2.20e-04	32	14	2	int:FST
GeneFamily	Ring finger proteins	ZFP36L1 ZFP36L2	9.57e-03	275	10	2	58
Coexpression	MANNO_MIDBRAIN_NEUROTYPES_HPROGM	ZFP36L1 ZFP36L2 BMP4 CRB2	1.68e-05	307	14	4	M39058
Coexpression	AMIT_DELAYED_EARLY_GENES	ZFP36L1 ZFP36L2	4.03e-05	18	14	2	M10550
Coexpression	MANNO_MIDBRAIN_NEUROTYPES_HRGL2B	ZFP36L1 ZFP36L2 LAMA5 CRB2	6.80e-05	439	14	4	M39054
Coexpression	DESCARTES_FETAL_SPLEEN_MESOTHELIAL_CELLS	LAMA5 BMP4 CRB2	1.37e-04	194	14	3	M40292
Coexpression	GSE42088_UNINF_VS_LEISHMANIA_INF_DC_24H_UP	ZFP36L1 ZFP36L2 PIGB	1.50e-04	200	14	3	M9895
Coexpression	GSE22140_HEALTHY_VS_ARTHRITIC_GERMFREE_MOUSE_CD4_TCELL_UP	ZFP36L1 ZFP36L2 PIGB	1.50e-04	200	14	3	M7648
Coexpression	GSE23568_ID3_TRANSDUCED_VS_ID3_KO_CD8_TCELL_DN	ZFP36L1 ZFP36L2 FRMD8	1.50e-04	200	14	3	M8506
Coexpression	CHICAS_RB1_TARGETS_CONFLUENT	ZFP36L2 BMP4 C1S RELN	1.83e-04	567	14	4	M2129
ToppCell	primary_visual_cortex-Non-neuronal-oligodendrocyte-Oligo-OPC_Pdgfra_Grm5\|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	ZFP36L1 ZFP36L2 BMP4	1.02e-05	139	14	3	a957ea4e581646c76b16b6a7f89579b8c7ac35b6
ToppCell	normal_Lung-Fibroblasts-Mesothelial_cells\|normal_Lung / Location, Cell class and cell subclass	BMP4 C1S CRB2	2.08e-05	176	14	3	f31d7234053085a82cf9d55aeedd1e04d34789c3
ToppCell	3'-GW_trimst-1-SmallIntestine-Epithelial-epithelial_progenitor_cell-CLDN10+_cells\|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	INHA RELN CFAP61	2.18e-05	179	14	3	7eca1e19ae6b5b1f18c721691dc3e860705628f2
ToppCell	tumor_Lung-Fibroblasts-Mesothelial_cells\|tumor_Lung / Location, Cell class and cell subclass	INHA C1S CRB2	2.37e-05	184	14	3	b0a251030d127858e68cf164be158f209a4d720f
ToppCell	3'-GW_trimst-1-LargeIntestine-Mesenchymal-mesothelial_cell-Mesothelium_(RGS5+)\|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	LAMA5 BMP4 CRB2	2.41e-05	185	14	3	11fbea1eb1d9a3e4480d0d2b0f7b02e2866b8142
ToppCell	5'-Adult-LargeIntestine-Mesenchymal-fibroblastic-Stromal_2_(NPY+)\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	LAMA5 BMP4 C1S	2.53e-05	188	14	3	997dcfc4f08738ab398d8abc15e4fd2fc6619862
ToppCell	droplet-Lung-3m-Mesenchymal-fibroblast\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	ZFP36L1 BMP4 C1S	2.65e-05	191	14	3	44a9a6768084dafc641ad455b65862bfd4cc0cb9
ToppCell	droplet-Lung-3m-Mesenchymal\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	ZFP36L1 BMP4 C1S	2.69e-05	192	14	3	086b47f87283cd41139cd56686011f8b5821b0da
ToppCell	3'-GW_trimst-1-LargeIntestine-Mesenchymal-mesothelial_cell\|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	LAMA5 BMP4 CRB2	2.69e-05	192	14	3	2f539653a20006bef814e6b4acd1023d6fdad5c6
ToppCell	droplet-Bladder-nan-3m\|Bladder / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ZFP36L1 BMP4 C1S	2.73e-05	193	14	3	e55f79bad6888b84b0ad5fccded498b170e3c6dc
ToppCell	facs-Bladder-nan-18m-Epithelial-bladder_mesenchymal_cell_(Car3+)\|Bladder / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ZFP36L1 BMP4 C1S	2.77e-05	194	14	3	f4c9fc53ae31d58096906d9305b0b4082512a7e9
ToppCell	droplet-Bladder-nan-3m-Epithelial\|Bladder / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ZFP36L1 BMP4 C1S	2.77e-05	194	14	3	b294056f9bdc243263cf36dce7b62564144b9de1
ToppCell	Non-neuronal-Non-dividing\|World / Primary Cells by Cluster	ZFP36L1 ZFP36L2 CRB2	2.77e-05	194	14	3	0add09d97192b34bd506209ab5f1a77182f498fc
ToppCell	Non-neuronal-Non-dividing-Radial_Glia\|World / Primary Cells by Cluster	ZFP36L1 ZFP36L2 CRB2	2.77e-05	194	14	3	1445b7611c2b1ab9b320f330d17d70117892cc28
ToppCell	tumor_Lung\|World / Location, Cell class and cell subclass	ZFP36L1 ZFP36L2 C1S	2.77e-05	194	14	3	7e6b8a30f8d08252ad3f1df826d6f7c0ba997c2c
ToppCell	kidney_cells-Renal_AKI_(acute_kidney_injury)-Epithelial-Renal_corpuscle_epithelial_cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	C1S RELN CRB2	2.77e-05	194	14	3	1374600957c7d7f0b05fd2c1186f521b9096d4ef
ToppCell	Brain_organoid-organoid_Kanton_Nature-Organoid-1M-Stem_cells\|Organoid-1M / Sample Type, Dataset, Time_group, and Cell type.	ZFP36L2 BMP4 RELN	2.82e-05	195	14	3	2fa0216ba493d9722324c0a9a0c59c40e72b3c4e
ToppCell	facs-Bladder-nan-18m-Epithelial-bladder_cell\|Bladder / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ZFP36L1 BMP4 C1S	2.82e-05	195	14	3	3e4f9ecfaa756386d816a26313b7229ec092d4e6
ToppCell	Brain_organoid-organoid_Kanton_Nature-Organoid-1M-Stem_cells-retina_progenitors\|Organoid-1M / Sample Type, Dataset, Time_group, and Cell type.	ZFP36L2 BMP4 RELN	2.82e-05	195	14	3	06a437459717dc3c41ec343b1ec57cf910ecbdd8
ToppCell	kidney_cells-Renal_AKI_(acute_kidney_injury)-Epithelial-Renal_corpuscle_epithelial_cell-parietal_epithelial_cell-Parietal_Epithelial_Cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	C1S RELN CRB2	2.86e-05	196	14	3	3cb74f1a333a82cac2b459f2f1517e2acf22b5fd
ToppCell	Brain_organoid-organoid_Kanton_Nature-Organoid-1M\|organoid_Kanton_Nature / Sample Type, Dataset, Time_group, and Cell type.	ZFP36L1 BMP4 CRB2	2.86e-05	196	14	3	1e9ccbd5be7839a74108f0cd07a6d2d736bc7f1b
ToppCell	Smart-seq2-lymph_node_(Smart-seq2)\|Smart-seq2 / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type	P2RX5 ZFP36L1 ZFP36L2	2.86e-05	196	14	3	3a8bd09a09c19df27c954d448f1bae945314c221
ToppCell	kidney_cells-Renal_AKI_(acute_kidney_injury)-Epithelial-Renal_corpuscle_epithelial_cell-parietal_epithelial_cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	C1S RELN CRB2	2.86e-05	196	14	3	023477a499a2c190f363cfdbc9d9c646733a6541
ToppCell	kidney_cells-Hypertensive_with+without-CKD-Epithelial-Renal_corpuscle_epithelial_cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	C1S RELN CRB2	2.86e-05	196	14	3	545d2e4469924d333e3f655f559c899fa1260196
ToppCell	3'-Adult-LargeIntestine\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	ZFP36L1 ZFP36L2 C1S	2.90e-05	197	14	3	03646005921bc330b7a9f66889ef1a7b9a3d530e
ToppCell	LPS_anti-TNF-Mesenchymal_fibroblastic-Fibroblasts-Activated_MatrixFB\|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type	ZFP36L1 BMP4 C1S	2.90e-05	197	14	3	fdb92985f7df0c280b87d3e43c2394e70786a2c7
ToppCell	B_cells-Naive_B_cells_\|B_cells / Immune cells in Rheumatoid Arthritis Joint Synovial Tissues	ZFP36L1 ZFP36L2 PIGB	2.90e-05	197	14	3	fd5fdc5289d681d59ff22d72e4de6e74c6c7aac6
ToppCell	5'-GW_trimst-2-LargeIntestine-Mesenchymal-fibroblastic-Stromal_2_(NPY+)\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	LAMA5 BMP4 C1S	2.90e-05	197	14	3	ea746772adb9df4ddb0508d4ef35f2027bf09c35
ToppCell	5'-GW_trimst-1.5-SmallIntestine-Mesenchymal-fibroblastic-Stromal_2_(NPY+)\|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	LAMA5 BMP4 C1S	2.90e-05	197	14	3	2e3d64648a1e4f01b9256a96b94b8a640ee1824c
ToppCell	Brain_organoid-organoid_Paulsen_bioRxiv-6_mon-Macroglial\|6_mon / Sample Type, Dataset, Time_group, and Cell type.	ZFP36L1 ZFP36L2 CRB2	2.90e-05	197	14	3	965d5a3f8c9b12cb8a8d3429702ae29ebd8c6122
ToppCell	5'-GW_trimst-2-SmallIntestine-Mesenchymal-fibroblastic-Stromal_2_(NPY+)\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	LAMA5 BMP4 C1S	2.90e-05	197	14	3	1da8ba5bbab232add6e43ad78b15c2339d0c2bc3
ToppCell	Brain_organoid-organoid_Paulsen_bioRxiv-6_mon-Macroglial-Astroglia\|6_mon / Sample Type, Dataset, Time_group, and Cell type.	ZFP36L1 ZFP36L2 CRB2	2.90e-05	197	14	3	3f088eb29197bc575400d6dafd8083e69e4a149f
ToppCell	3'-GW_trimst-2-SmallIntestine-Mesenchymal-fibroblastic-Stromal_2_(NPY+)\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	LAMA5 BMP4 C1S	2.90e-05	197	14	3	d9e196c8b4a6ede4733946dbdba3331534954beb
ToppCell	5'-GW_trimst-2\|5' / Celltypes from developing, pediatric, Crohn's, & adult GI tract	ZFP36L1 C1S SEPTIN2	2.95e-05	198	14	3	677816ea6d1706d99b7757d43b6b375276b25639
ToppCell	Brain_organoid-organoid_Velasco_nature-6_mon-Macroglial-Astroglia\|6_mon / Sample Type, Dataset, Time_group, and Cell type.	ZFP36L1 ZFP36L2 CRB2	2.95e-05	198	14	3	715ecad21f572b195ff3b78216b1a7b32bbb4ace
ToppCell	Brain_organoid-organoid_Velasco_nature-6_mon\|organoid_Velasco_nature / Sample Type, Dataset, Time_group, and Cell type.	ZFP36L1 ZFP36L2 CRB2	2.95e-05	198	14	3	a6f65bb0845d8f64f5c7edb00cee3ca5adb1a373
ToppCell	Brain_organoid-organoid_Velasco_nature-3_mon-Radial_glial-oRG\|3_mon / Sample Type, Dataset, Time_group, and Cell type.	ZFP36L1 ZFP36L2 CRB2	2.95e-05	198	14	3	72dc49aa107d0cc6206eb67b577c73e190855125
ToppCell	3'-GW_trimst-1-SmallIntestine-Mesenchymal-fibroblastic-Stromal_2_(NPY+)\|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	LAMA5 BMP4 C1S	2.95e-05	198	14	3	4a4566f86c9365a41b4cfd1609eac09bd73b3f34
ToppCell	Brain_organoid-organoid_Velasco_nature-6_mon-Macroglial\|6_mon / Sample Type, Dataset, Time_group, and Cell type.	ZFP36L1 ZFP36L2 CRB2	2.95e-05	198	14	3	9d03768f8b6c74e060c5f045508538f9b331f469
ToppCell	15-Airway-Mesenchymal-Mesenchyme_SERPINF1-high\|Airway / Age, Tissue, Lineage and Cell class	ZFP36L1 BMP4 C1S	2.95e-05	198	14	3	3d76393e72eed59b4dd16130ef5dd1d331ba5711
ToppCell	3'-Child09-12-SmallIntestine-Mesenchymal-fibroblastic-Stromal_2_(NPY+)\|Child09-12 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	LAMA5 BMP4 C1S	2.95e-05	198	14	3	d83707b69fb64721ac3cff90ba58cdd999d6b386
ToppCell	Brain_organoid-organoid_Kanton_Nature-Organoid-2M-Radial_glial\|Organoid-2M / Sample Type, Dataset, Time_group, and Cell type.	ZFP36L1 ZFP36L2 CRB2	2.99e-05	199	14	3	75ff9a5df156c6632883eab79573f1c02c985803
ToppCell	Non-neuronal-Non-dividing-Radial_Glia-early\|World / Primary Cells by Cluster	ZFP36L1 ZFP36L2 CRB2	2.99e-05	199	14	3	549391e7a4285da1c0e366654530bcf1cd33fbae
ToppCell	kidney_cells-Hypertensive_with+without-CKD-Epithelial-Renal_corpuscle_epithelial_cell-parietal_epithelial_cell-Parietal_Epithelial_Cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	C1S RELN CRB2	2.99e-05	199	14	3	c972d3036151403f26fa9d6271520639c281ab84
ToppCell	kidney_cells-Hypertensive_with+without-CKD-Epithelial-Renal_corpuscle_epithelial_cell-parietal_epithelial_cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	C1S RELN CRB2	2.99e-05	199	14	3	b9338b739162cd8e5661c9a4dcb41a31219b5723
ToppCell	LPS_IL1RA_TNF-Mesenchymal_fibroblastic-Fibroblasts-MatrixFB\|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type	ZFP36L1 BMP4 C1S	2.99e-05	199	14	3	30d3e8c0681ec11f86dd38c5f48d21187a1b4f90
ToppCell	Non-neuronal-Non-dividing-Radial_Glia-early-40\|World / Primary Cells by Cluster	ZFP36L1 ZFP36L2 CRB2	2.99e-05	199	14	3	23625d757173bdd35a51c7919ff4b588168d2553
ToppCell	5'-GW_trimst-1.5-LargeIntestine-Mesenchymal-immature_mesenchymal_cell-Mesoderm_2_(ZEB2+)\|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	ZFP36L1 ZFP36L2 BMP4	2.99e-05	199	14	3	a95aa72387c9558e0316898eaa9df4de8932af1b
ToppCell	Brain_organoid-organoid_Velasco_nature-6_mon-Radial_glial-oRG/Astroglia\|6_mon / Sample Type, Dataset, Time_group, and Cell type.	ZFP36L1 ZFP36L2 CRB2	2.99e-05	199	14	3	0b96fad1be02f0fe7a608207770cc56a6b6b291e
ToppCell	5'-GW_trimst-2-LargeIntestine-Mesenchymal\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	ZFP36L1 BMP4 C1S	2.99e-05	199	14	3	3d8c76e3d05acf72a35ca755b51579fc3ae63562
ToppCell	LPS_IL1RA_TNF-Mesenchymal_fibroblastic-Fibroblasts-Activated_MatrixFB\|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type	ZFP36L1 BMP4 C1S	2.99e-05	199	14	3	e1849505b92820a219c5a2c35492bdd55579fb48
ToppCell	3'-Pediatric_IBD-SmallIntestine-Mesenchymal-fibroblastic-Stromal_2_(NPY+)\|Pediatric_IBD / Celltypes from developing, pediatric, Crohn's, & adult GI tract	LAMA5 BMP4 C1S	2.99e-05	199	14	3	ec74ff85d6b61013b1f785b2fca343759feb7843
ToppCell	5'-GW_trimst-1.5-SmallIntestine-Mesenchymal-fibroblastic\|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	LAMA5 BMP4 C1S	2.99e-05	199	14	3	edba1833ef5c4ca122d7c32f97670314e005f93b
ToppCell	356C-Fibroblasts-Fibroblast-J_(Lipofibroblast)\|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)	ZFP36L2 C1S CRB2	2.99e-05	199	14	3	f4fdf94c561dca35bb17766d908c5030655f43eb
ToppCell	5'-GW_trimst-1.5-LargeIntestine-Mesenchymal-immature_mesenchymal_cell\|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	ZFP36L1 ZFP36L2 BMP4	2.99e-05	199	14	3	bb201deb281619113edcd1de2af2d3eb21b967b8
ToppCell	Brain_organoid-organoid_Velasco_nature-3_mon-Radial_glial\|3_mon / Sample Type, Dataset, Time_group, and Cell type.	ZFP36L1 ZFP36L2 CRB2	2.99e-05	199	14	3	0fee11bd72b27202f8d9fa4daba831ea9c8a61b2
ToppCell	Brain_organoid-organoid_Paulsen_bioRxiv-3.5_mon-Radial_glial\|3.5_mon / Sample Type, Dataset, Time_group, and Cell type.	ZFP36L1 ZFP36L2 CRB2	2.99e-05	199	14	3	6fd9774f18da3e6f114427f55a8879ac90c41350
ToppCell	Basal\|World / shred by cell class for turbinate	ZFP36L2 BMP4 C1S	2.99e-05	199	14	3	d9fe184a7d3251f871eba3123e0127aa1a6f2949
ToppCell	LPS_only-Mesenchymal_fibroblastic-Fibroblasts\|LPS_only / Treatment groups by lineage, cell group, cell type	ZFP36L1 BMP4 C1S	2.99e-05	199	14	3	1a0add79f4e34078b3475eb11c85a4234bda197c
ToppCell	3'-GW_trimst-1-SmallIntestine-Mesenchymal-fibroblastic-Stromal_1_(ADAMDEC1+)\|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	ZFP36L2 BMP4 C1S	2.99e-05	199	14	3	a697b3f0760e66bad8ea8d83cf6fea5934692c56
ToppCell	LPS_only-Mesenchymal_fibroblastic\|LPS_only / Treatment groups by lineage, cell group, cell type	ZFP36L1 BMP4 C1S	2.99e-05	199	14	3	211c3a08f2d484ab7a3368006767289088f0d957
ToppCell	5'-GW_trimst-1.5-SmallIntestine-Mesenchymal-fibroblastic-Stromal_1_(ADAMDEC1+)\|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	ZFP36L2 BMP4 C1S	2.99e-05	199	14	3	bdedcc7c8f3be0996200c882dda82fb2658655c0
ToppCell	356C-Fibroblasts-Fibroblast-J_(Lipofibroblast)-\|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)	ZFP36L2 C1S CRB2	2.99e-05	199	14	3	c0fe99ed906d0eb99cccdab9a1fa32c17b3542e7
ToppCell	LPS_only-Mesenchymal_fibroblastic-Fibroblasts-Diff_MatrixFB\|LPS_only / Treatment groups by lineage, cell group, cell type	ZFP36L1 BMP4 C1S	3.04e-05	200	14	3	ab4fda0cc95cb8f80ea9f28745013f3248def820
ToppCell	LPS_only-Mesenchymal_fibroblastic-Fibroblasts-MatrixFB\|LPS_only / Treatment groups by lineage, cell group, cell type	ZFP36L1 BMP4 C1S	3.04e-05	200	14	3	a7ef7022b8efcaedb7319b0b43d8c4e99d788fe2
ToppCell	normal_Lung-Fibroblasts-COL14A1+_matrix_FBs\|Fibroblasts / Location, Cell class and cell subclass	ZFP36L1 ZFP36L2 C1S	3.04e-05	200	14	3	6d8f6a6b3f61c529fbed1376659641030abf4f2c
ToppCell	Brain_organoid-organoid_Tanaka_cellReport-10w-Macroglial-Astrocyte\|10w / Sample Type, Dataset, Time_group, and Cell type.	ZFP36L1 ZFP36L2 CRB2	3.04e-05	200	14	3	75f5ea38fbd341b80a8058077a04447f0e0eea28
ToppCell	Brain_organoid-organoid_Tanaka_cellReport-3m-Macroglial-Astrocyte\|3m / Sample Type, Dataset, Time_group, and Cell type.	ZFP36L1 ZFP36L2 CRB2	3.04e-05	200	14	3	98d7f577b31a603bf835bf9b4ea31999445cf0e5
ToppCell	Brain_organoid-organoid_Tanaka_cellReport-10w-Macroglial\|10w / Sample Type, Dataset, Time_group, and Cell type.	ZFP36L1 ZFP36L2 CRB2	3.04e-05	200	14	3	bda719369aa199902789061e223b129f70a1317a
ToppCell	Brain_organoid-organoid_Kanton_Nature-Organoid-4M-Radial_glial\|Organoid-4M / Sample Type, Dataset, Time_group, and Cell type.	ZFP36L1 ZFP36L2 CRB2	3.04e-05	200	14	3	ed4a41cb6782541d8fc928aaa12cf03bc1c630a2
ToppCell	Brain_organoid-organoid_Kanton_Nature-Organoid-2M-Radial_glial-RGCs_3\|Organoid-2M / Sample Type, Dataset, Time_group, and Cell type.	ZFP36L1 ZFP36L2 CRB2	3.04e-05	200	14	3	55a1df656545ff078b727d55e4d65d61ddb5c41f
ToppCell	Brain_organoid-organoid_Paulsen_bioRxiv-3_mon-Radial_glial\|3_mon / Sample Type, Dataset, Time_group, and Cell type.	ZFP36L1 ZFP36L2 CRB2	3.04e-05	200	14	3	49197316231e45f8c9f007f55b036600f7195922
ToppCell	Brain_organoid-organoid_Tanaka_cellReport-3m-Macroglial\|3m / Sample Type, Dataset, Time_group, and Cell type.	ZFP36L1 ZFP36L2 CRB2	3.04e-05	200	14	3	38b51f337e183011e3ff32997ec26d8a424c6b78
ToppCell	Brain_organoid-organoid_Paulsen_bioRxiv-3_mon-Radial_glial-RG\|3_mon / Sample Type, Dataset, Time_group, and Cell type.	ZFP36L1 ZFP36L2 CRB2	3.04e-05	200	14	3	dea7928d6ceb7a347f56c6d0c9c7a56b7a2c0a80
ToppCell	Entopeduncular-Macroglia-ASTROCYTE-Gja1-Astrocyte.Gja1.Htra1_(Htra1)-\|Entopeduncular / BrainAtlas - Mouse McCarroll V32	C1S CRB2	1.97e-04	67	14	2	8502da9042f40e0a44354776bb507e18ef0cda43
ToppCell	Entopeduncular-Macroglia-ASTROCYTE-Gja1-Astrocyte.Gja1.Htra1_(Htra1)--\|Entopeduncular / BrainAtlas - Mouse McCarroll V32	C1S CRB2	1.97e-04	67	14	2	e6d051404f095ab9ca95fa6e5ecf0905573a5a63
ToppCell	Entopeduncular-Macroglia-ASTROCYTE-Gja1-Astrocyte.Gja1.Htra1_(Htra1)\|Entopeduncular / BrainAtlas - Mouse McCarroll V32	C1S CRB2	1.97e-04	67	14	2	3a3a3e76f67c1d33bd7b1d0d94c522ad1e1192f8
ToppCell	lymphoid-B_cell-Naive_B_cell\|B_cell / Lineage, cell class and subclass	P2RX5 ZFP36L1	2.80e-04	80	14	2	dd2ecd244cd2cf770ada756ac96e34afc3301772
ToppCell	frontal_cortex-Neuronal-glutamatergic_neuron-CR-CR_Lhx5\|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	P2RX5 RELN	3.24e-04	86	14	2	2990429ed4438f41ff03f4a9cae8863a528fdd81
ToppCell	frontal_cortex-Neuronal-glutamatergic_neuron-CR\|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	P2RX5 RELN	3.24e-04	86	14	2	97467708c90a4bd49deafe3e2ec495c56b448ce1
ToppCell	Bronchial_Biopsy-Mesenchymal-Fibroblasts\|Mesenchymal / Tissue, Lineage and Cell class of Lung Cells from 10X	ZFP36L2 C1S	7.26e-04	129	14	2	13cd10ffdd8f1ef7721884e9efd2cf25f170f414
ToppCell	frontal_cortex-Non-neuronal-oligodendrocyte-Oligo-OPC_Pdgfra_Grm5\|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	ZFP36L1 ZFP36L2	7.71e-04	133	14	2	63d2f096ae47d9b587acc6c5fbd346e5e58842b8
ToppCell	3'_v3-Lung-Lymphocytic_T_CD8-Trm_gut_CD8\|Lung / Manually curated celltypes from each tissue	ZFP36L2 BMP4	8.66e-04	141	14	2	7cbe8abdd004430d58ce31e0b613894a4cf6726e
ToppCell	356C-Lymphocytic-CD8+_Cytotoxic_T-cell-CD8+_Cytotoxic_T_cell_1.5\|356C / Donor, Lineage, Cell class and subclass (all cells)	P2RX5 PIGB	9.92e-04	151	14	2	14c6f5d7441083861077b7362e6867d820aef864
ToppCell	Smart-seq2-bone_marrow_(Smart-seq2)-lymphocytic-B_lymphocytic-naive_B_cell\|bone_marrow_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type	P2RX5 ZFP36L1	9.92e-04	151	14	2	0f8f07e44c6edaf09574930b416fdce14d67095a
ToppCell	367C-Myeloid-Macrophage-FABP4+_Macrophage_2\|Macrophage / Donor, Lineage, Cell class and subclass (all cells)	BMP4 CFAP61	1.00e-03	152	14	2	7a1072315cce71eefe2d32149a107d5648999968
ToppCell	primary_visual_cortex-Non-neuronal-astrocyte\|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	ZFP36L1 ZFP36L2	1.02e-03	153	14	2	95b28c5bd10ffb74c0993ebd565038b9818e4bd2
ToppCell	primary_visual_cortex-Non-neuronal-astrocyte-Astro\|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	ZFP36L1 ZFP36L2	1.02e-03	153	14	2	b09f8def40a1ea56722f3398f61a036667b61cd9
ToppCell	primary_visual_cortex-Non-neuronal-astrocyte-Astro-Astro_Aqp4\|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	ZFP36L1 ZFP36L2	1.02e-03	153	14	2	3ab9d55b3db51715c1d61eca142384195ce4b54f
ToppCell	367C-Myeloid-Macrophage-FABP4+_Macrophage_2\|Myeloid / Donor, Lineage, Cell class and subclass (all cells)	BMP4 CFAP61	1.03e-03	154	14	2	6c1e7682c43c40b58b371c58deb10b839700ebcc
ToppCell	facs-Large_Intestine-Distal-3m-Epithelial-Lgr5-_amplifying_undifferentiated_cell\|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	P2RX5 LAMA5	1.04e-03	155	14	2	f3489a548a2c0cc2d9117ff85865c6089ea0835d
ToppCell	facs-Large_Intestine-Distal-3m-Epithelial-epithelial_cell_of_large_intestine\|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	P2RX5 LAMA5	1.04e-03	155	14	2	0e24e767a3895d31d34cabeaca0354aadae34e44
ToppCell	TCGA-Cervix-Primary_Tumor-Cervical_Carcinoma-Keratinizing_Cervical_Squamous_Cell_Carcinoma-3\|TCGA-Cervix / Sample_Type by Project: Shred V9	ZFP36L1 FRMD8	1.06e-03	156	14	2	ffb9249a115ce31f50b99a7a3d40bf48b9d7f2b0
ToppCell	PND07-28-samps-Mesenchymal-Mesothelial-Mesothelial\|PND07-28-samps / Age Group, Lineage, Cell class and subclass	C1S CRB2	1.06e-03	156	14	2	605d95a900e1443d3f6aae163ef2e893d3293203
ToppCell	PND07-28-samps-Mesenchymal-Mesothelial\|PND07-28-samps / Age Group, Lineage, Cell class and subclass	C1S CRB2	1.06e-03	156	14	2	574f761962a7dd3308bd41fc529dd3ea1b8625f8
ToppCell	frontal_cortex-Non-neuronal-astrocyte\|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	ZFP36L1 ZFP36L2	1.07e-03	157	14	2	803af734d7f775d294391e2b84e472a732e18cef
ToppCell	frontal_cortex-Non-neuronal-astrocyte-Astro-Astro_Aqp4\|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	ZFP36L1 ZFP36L2	1.07e-03	157	14	2	9aa5304a9704da6dd4eda7d6940494b00e38b2e8
ToppCell	3'-GW_trimst-1-LargeIntestine-Mesenchymal-fibroblastic-Stromal_2_(NPY+)\|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	LAMA5 BMP4	1.07e-03	157	14	2	1e3a4a7193d95f09d71c2dfe704b8e626c6d9624
ToppCell	frontal_cortex-Non-neuronal-astrocyte-Astro\|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	ZFP36L1 ZFP36L2	1.07e-03	157	14	2	0551442ae14685d8fe5729e3960c6324b1e05e4d
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Epithelial-Renal_corpuscle_epithelial_cell-parietal_epithelial_cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	LAMA5 CRB2	1.08e-03	158	14	2	e7db0ee4740e3c7a4d97d7cd7462e2c2ab458a4b
Drug	17-AAG; Down 200; 1uM; MCF7; HT_HG-U133A_EA	P2RX5 ZFP36L1 ZFP36L2 LAMA5	3.88e-06	184	14	4	1064_DN
Drug	pyrachlostrobin	ZFP36L2 LAMA5 FRMD8 BMP4 CRB2	8.67e-05	811	14	5	ctd:C513428
Drug	Trichostatin A, Streptomyces sp.; Down 200; 1uM; MCF7; HT_HG-U133A	ZFP36L1 ZFP36L2 LAMA5	1.38e-04	169	14	3	5231_DN
Drug	Piperlongumine [20069-09-4]; Down 200; 12.6uM; MCF7; HT_HG-U133A	ZFP36L1 ZFP36L2 LAMA5	1.61e-04	178	14	3	2757_DN
Drug	Camptothecine (S,+) [7689-03-4]; Up 200; 11.4uM; PC3; HT_HG-U133A	ZFP36L1 ZFP36L2 BMP4	1.63e-04	179	14	3	4541_UP
Drug	Trichostatin A, Streptomyces sp.; Down 200; 1uM; MCF7; HT_HG-U133A	ZFP36L1 ZFP36L2 LAMA5	1.69e-04	181	14	3	6951_DN
Drug	Trichostatin A, from Streptomyces sp.; Down 200; 0.1uM; MCF7; HT_HG-U133A	P2RX5 ZFP36L1 ZFP36L2	1.69e-04	181	14	3	7005_DN
Drug	Parthenolide [20554-84-1]; Down 200; 16.2uM; MCF7; HT_HG-U133A	ZFP36L1 ZFP36L2 LAMA5	1.74e-04	183	14	3	5530_DN
Drug	17-AAG; Down 200; 1uM; MCF7; HT_HG-U133A_EA	P2RX5 ZFP36L1 ZFP36L2	1.83e-04	186	14	3	916_DN
Drug	geldanamycin; Down 200; 1uM; MCF7; HT_HG-U133A_EA	ZFP36L1 ZFP36L2 LAMA5	1.83e-04	186	14	3	1066_DN
Drug	17-AAG; Down 200; 1uM; MCF7; HT_HG-U133A	P2RX5 ZFP36L1 ZFP36L2	1.86e-04	187	14	3	1631_DN
Drug	retinoic acid; Down 200; 1uM; MCF7; HT_HG-U133A	ZFP36L1 ZFP36L2 BMP4	1.92e-04	189	14	3	5208_DN
Drug	17-AAG; Down 200; 1uM; MCF7; HT_HG-U133A_EA	P2RX5 ZFP36L1 ZFP36L2	1.95e-04	190	14	3	1056_DN
Drug	geldanamycin; Down 200; 1uM; MCF7; HG-U133A	P2RX5 ZFP36L1 ZFP36L2	2.01e-04	192	14	3	611_DN
Drug	17-AAG; Down 200; 1uM; MCF7; HT_HG-U133A	P2RX5 ZFP36L1 ZFP36L2	2.04e-04	193	14	3	6985_DN
Drug	Equilin [474-86-2]; Down 200; 15uM; MCF7; HT_HG-U133A	ZFP36L1 ZFP36L2 BMP4	2.07e-04	194	14	3	5620_DN
Drug	trifluoperazine dihydrochloride; Down 200; 10uM; MCF7; HT_HG-U133A	ZFP36L1 ZFP36L2 BMP4	2.07e-04	194	14	3	5221_DN
Drug	Karakoline [39089-30-0]; Down 200; 10.6uM; MCF7; HT_HG-U133A	ZFP36L1 ZFP36L2 BMP4	2.10e-04	195	14	3	6059_DN
Drug	17-DMAG; Down 200; 0.1uM; MCF7; HT_HG-U133A	ZFP36L1 ZFP36L2 LAMA5	2.10e-04	195	14	3	6973_DN
Drug	Thiocolchicoside [602-41-5]; Up 200; 7uM; MCF7; HT_HG-U133A	ZFP36L1 ZFP36L2 INHA	2.10e-04	195	14	3	2875_UP
Drug	Idazoxan hydrochloride [79944-56-2]; Up 200; 16.6uM; MCF7; HT_HG-U133A	ZFP36L2 BMP4 RELN	2.10e-04	195	14	3	6465_UP
Drug	Hesperetin [520-33-2]; Up 200; 13.2uM; MCF7; HT_HG-U133A	ZFP36L1 ZFP36L2 BMP4	2.13e-04	196	14	3	5350_UP
Drug	PHA-00767505E [723337-45-9]; Down 200; 10uM; PC3; HT_HG-U133A	ZFP36L2 BMP4 C1S	2.13e-04	196	14	3	6591_DN
Drug	Bemegride [64-65-3]; Up 200; 25.8uM; MCF7; HT_HG-U133A	ZFP36L1 ZFP36L2 BMP4	2.13e-04	196	14	3	5014_UP
Drug	Erythromycin [114-07-8]; Up 200; 5.4uM; MCF7; HT_HG-U133A	INHA BMP4 RELN	2.16e-04	197	14	3	1510_UP
Drug	Stachydrine hydrochloride; Down 200; 22.2uM; MCF7; HT_HG-U133A	P2RX5 ZFP36L2 BMP4	2.16e-04	197	14	3	6805_DN
Drug	Corynanthine hydrochloride [66634-44-4]; Up 200; 10.2uM; MCF7; HT_HG-U133A	ZFP36L1 ZFP36L2 RELN	2.16e-04	197	14	3	2786_UP
Drug	Dropropizine (R,S) [17692-31-8]; Up 200; 17uM; PC3; HT_HG-U133A	ZFP36L1 ZFP36L2 C1S	2.16e-04	197	14	3	5106_UP
Drug	S(-)-terguride hydrogen maleate [37686-85-4]; Up 200; 8.8uM; MCF7; HT_HG-U133A	ZFP36L1 ZFP36L2 BMP4	2.20e-04	198	14	3	6473_UP
Drug	sodium 4-phenylbutyrate; Up 200; 200uM; SKMEL5; HG-U133A	ZFP36L2 LAMA5 RELN	2.23e-04	199	14	3	502_UP
Drug	2-Chloropyrazine [14508-49-7]; Up 200; 35uM; MCF7; HT_HG-U133A	ZFP36L1 ZFP36L2 RELN	2.23e-04	199	14	3	3570_UP
Drug	Racecadotril [81110-73-8]; Up 200; 10.4uM; PC3; HT_HG-U133A	ZFP36L2 BMP4 C1S	2.26e-04	200	14	3	5755_UP
Drug	balofloxacin	INHA LAMA5	2.98e-04	42	14	2	CID000065958
Drug	dibutyryl cyclic 3',5'-AMP	INHA LAMA5 BMP4 C1S	3.00e-04	561	14	4	CID000002460
Drug	AR E	ZFP36L1 ZFP36L2 BMP4	3.41e-04	230	14	3	CID004369394
Disease	brain volume measurement	ZFP36L1 BMP4 RELN CRB2	1.01e-04	595	13	4	EFO_0006930
Disease	suicide behaviour	P2RX5 FRMD8	1.68e-04	44	13	2	EFO_0007623
Disease	polyp of colon	LAMA5 BMP4	2.72e-04	56	13	2	MONDO_0021400
Disease	Global developmental delay	BMP4 PIGB	1.52e-03	133	13	2	C0557874

Protein segments in the cluster

Peptide	Gene	Start	Entry
CFDLGPFHGLCFPHP	CFAP61	256	Q8NHU2
GYQAFYCHGDCPFPL	BMP4	331	P12644
FSFRHAAGFLCHCPP	CRB2	296	Q5IJ48
CHELPFYGCAFFHGE	FRMD8	261	Q9BZ67
CHKLPFYGCAFFHGE	FRMD8P1	261	Q9BZ68
FAGPHCDRCRPGYHG	LAMA5	611	O15230
PRFSPFFFLCTHHGE	RELN	31	P78509
IGGYFCSCPPEYFLH	C1S	151	P09871
VYPPSFIFHYCHGGC	INHA	281	P05111
FIFHYCHGGCGLHIP	INHA	286	P05111
HFGPKNHYCPIFRLG	P2RX5	221	Q93086
GTHLPFFIHGCYLAP	PIGB	321	Q92521
FHTIGFCPYGPRCHF	ZFP36L1	161	Q07352
VHCCFYFISPFGHGL	SEPTIN2	146	Q15019
LCRTFHTIGFCPYGP	ZFP36L2	196	P47974
HTIGFCPYGPRCHFI	ZFP36L2	201	P47974