Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionoleoyl-CoA ligase activity

ACSL1 ACSL5

5.49e-054612GO:0090434
GeneOntologyMolecularFunctionalkaline phosphatase activity

ALPI ALPG

1.37e-046612GO:0004035
GeneOntologyMolecularFunctionhyalurononglucosaminidase activity

HYAL1 HYAL3

3.26e-049612GO:0004415
GeneOntologyMolecularFunctionarachidonate-CoA ligase activity

ACSL1 ACSL5

4.96e-0411612GO:0047676
GeneOntologyBiologicalProcesscoenzyme A catabolic process

VNN1 ALPI ALPG

2.25e-069633GO:0015938
GeneOntologyBiologicalProcessnucleoside bisphosphate catabolic process

VNN1 ALPI ALPG

2.54e-0519633GO:0033869
GeneOntologyBiologicalProcessribonucleoside bisphosphate catabolic process

VNN1 ALPI ALPG

2.54e-0519633GO:0034031
GeneOntologyBiologicalProcesspurine nucleoside bisphosphate catabolic process

VNN1 ALPI ALPG

2.54e-0519633GO:0034034
GeneOntologyBiologicalProcesspositive regulation of long-chain fatty acid import across plasma membrane

ACSL1 ACSL5

2.75e-053632GO:0010747
GeneOntologyBiologicalProcesscoenzyme A metabolic process

VNN1 ALPI ALPG

5.25e-0524633GO:0015936
GeneOntologyBiologicalProcesspositive regulation of long-chain fatty acid import into cell

ACSL1 ACSL5

5.49e-054632GO:0140214
GeneOntologyBiologicalProcessnucleoside bisphosphate metabolic process

ACSL1 VNN1 ACSL5 ALPI ALPG

7.35e-05142635GO:0033865
GeneOntologyBiologicalProcessribonucleoside bisphosphate metabolic process

ACSL1 VNN1 ACSL5 ALPI ALPG

7.35e-05142635GO:0033875
GeneOntologyBiologicalProcesspurine nucleoside bisphosphate metabolic process

ACSL1 VNN1 ACSL5 ALPI ALPG

7.35e-05142635GO:0034032
GeneOntologyBiologicalProcessregulation of long-chain fatty acid import across plasma membrane

ACSL1 ACSL5

1.91e-047632GO:0010746
GeneOntologyBiologicalProcessregulation of long-chain fatty acid import into cell

ACSL1 ACSL5

3.26e-049632GO:0140212
DomainAlk_phosphatase

ALPI ALPG

6.27e-054612PF00245
DomainAlkaline_phosphatase_AS

ALPI ALPG

6.27e-054612IPR018299
DomainAlkaline_phosphatase

ALPI ALPG

6.27e-054612IPR001952
DomainalkPPc

ALPI ALPG

6.27e-054612SM00098
DomainALKALINE_PHOSPHATASE

ALPI ALPG

6.27e-054612PS00123
DomainHyaluronidase

HYAL1 HYAL3

1.04e-045612IPR018155
DomainGlyco_hydro_56

HYAL1 HYAL3

1.04e-045612PF01630
DomainGPCR_3

GPRC6A GPRC5D

2.12e-0321612IPR000337
DomainEPHD

KMT2B KDM4A

2.32e-0322612PS51805
Domain7tm_3

GPRC6A GPRC5D

2.32e-0322612PF00003
DomainG_PROTEIN_RECEP_F3_2

GPRC6A GPRC5D

2.32e-0322612PS00980
DomainG_PROTEIN_RECEP_F3_3

GPRC6A GPRC5D

2.32e-0322612PS00981
DomainG_PROTEIN_RECEP_F3_1

GPRC6A GPRC5D

2.32e-0322612PS00979
DomainG_PROTEIN_RECEP_F3_4

GPRC6A GPRC5D

2.32e-0322612PS50259
DomainGPCR_3_C

GPRC6A GPRC5D

2.32e-0322612IPR017978
DomainAMP-binding_CS

ACSL1 ACSL5

3.24e-0326612IPR020845
DomainAMP_BINDING

ACSL1 ACSL5

3.76e-0328612PS00455
DomainAMP-binding

ACSL1 ACSL5

4.30e-0330612PF00501
DomainAMP-dep_Synth/Lig

ACSL1 ACSL5

4.30e-0330612IPR000873
DomainAlkaline_phosphatase_core

ALPI ALPG

4.59e-0331612IPR017850
DomainAlkaline_Pase-like_a/b/a

ALPI ALPG

4.59e-0331612IPR017849
Domain-

ALPI ALPG

4.59e-03316123.40.720.10
Pubmed

Hydrolysis and absorption of pantothenate and its coenzymes in the rat small intestine.

VNN1 ALPI ALPG

1.18e-0766436619987
Pubmed

Regulation of hyaluronidase activity by alternative mRNA splicing.

HYAL1 HYAL3

3.33e-06264212084718
Pubmed

Mutations in HYAL1, a member of a tandemly distributed multigene family encoding disparate hyaluronidase activities, cause a newly described lysosomal disorder, mucopolysaccharidosis IX.

HYAL1 HYAL3

3.33e-06264210339581
Pubmed

Hyal-1 but not Hyal-3 deficiency has an impact on ovarian folliculogenesis and female fertility by altering the follistatin/activin/Smad3 pathway and the apoptotic process.

HYAL1 HYAL3

3.33e-06264221732362
Pubmed

The nuclear structural protein NuMA is a negative regulator of 53BP1 in DNA double-strand break repair.

NUMA1 TP53BP1

3.33e-06264230812030
Pubmed

Persistent STAT5-mediated ROS production and involvement of aberrant p53 apoptotic signaling in the resistance of chronic myeloid leukemia to imatinib.

TP53BP1 STAT5A

9.99e-06364229115375
Pubmed

Loss of long-chain acyl-CoA synthetase 1 promotes hepatocyte death in alcohol-induced steatohepatitis.

ACSL1 STAT5A

9.99e-06364236349655
Pubmed

Mammalian hyaluronidase induces ovarian granulosa cell apoptosis and is involved in follicular atresia.

HYAL1 HYAL3

9.99e-06364218653706
Pubmed

Two gene duplication events in the evolution of the human heat-stable alkaline phosphatases.

ALPI ALPG

9.99e-0636423443302
Pubmed

Association of long-chain acyl-coenzyme A synthetase 5 expression in human breast cancer by estrogen receptor status and its clinical significance.

ACSL1 ACSL5

9.99e-06364228498416
Pubmed

Involvement of hyaluronidases in colorectal cancer.

HYAL1 HYAL3

9.99e-06364220849597
Pubmed

Intestinal Alkaline Phosphatase Regulates Tight Junction Protein Levels.

ALPI ALPG

9.99e-06364227106638
Pubmed

Organic pyrophosphates as substrates for human alkaline phosphatases.

ALPI ALPG

9.99e-06364216742561
Pubmed

Expression and regulation patterns of hyaluronidases in small cell lung cancer and glioma lines.

HYAL1 HYAL3

9.99e-06364212684632
Pubmed

Hyaluronidase expression and activity is regulated by pro-inflammatory cytokines in human airway epithelial cells.

HYAL1 HYAL3

9.99e-06364218390475
Pubmed

Effects of disruption of the embryonic alkaline phosphatase gene on preimplantation development of the mouse.

ALPI ALPG

9.99e-06364210767088
Pubmed

MUSEAP, a novel reporter gene for the study of long-term gene expression in immunocompetent mice.

ALPI ALPG

9.99e-06364211722850
Pubmed

Nuclear IGF1R interacts with NuMA and regulates 53BP1‑dependent DNA double‑strand break repair in colorectal cancer.

NUMA1 TP53BP1

9.99e-06364234165167
Pubmed

Candidate tumor suppressor HYAL2 is a glycosylphosphatidylinositol (GPI)-anchored cell-surface receptor for jaagsiekte sheep retrovirus, the envelope protein of which mediates oncogenic transformation.

HYAL1 HYAL3

9.99e-06364211296287
Pubmed

Expression and cellular localization of human hyaluronidase-2 in articular chondrocytes and cultured cell lines.

HYAL1 HYAL3

9.99e-06364216600643
Pubmed

A novel phosphatase upregulated in Akp3 knockout mice.

ALPI ALPG

9.99e-06364217901166
Pubmed

Role of lysophosphatidylcholine in brush-border intestinal alkaline phosphatase release and restoration.

ALPI ALPG

9.99e-06364219407215
Pubmed

Ultraviolet-B irradiation induces differential regulations of hyaluronidase expression and activity in normal human keratinocytes.

HYAL1 HYAL3

9.99e-06364221699545
Pubmed

Expression and activity of hyaluronidases HYAL-1, HYAL-2 and HYAL-3 in the human intervertebral disc.

HYAL1 HYAL3

9.99e-06364231758257
Pubmed

Genomic structure and comparison of mouse tissue-specific alkaline phosphatase genes.

ALPI ALPG

9.99e-0636422286375
Pubmed

Interactions between CD36 and global intestinal alkaline phosphatase in mouse small intestine and effects of high-fat diet.

ALPI ALPG

2.00e-05464221900644
Pubmed

Hyaluronidases and CD44 undergo differential modulation during chondrogenesis.

HYAL1 HYAL3

2.00e-05464211944887
Pubmed

Stage-specific expression patterns of alkaline phosphatase during development of the first arch skeleton in inbred C57BL/6 mouse embryos.

ALPI ALPG

2.00e-0546429061447
Pubmed

Novel Role of the ALPI Gene Associated with Constipation Caused by Complement Component 3 Deficiency.

ALPI ALPG

2.00e-05464239273477
Pubmed

Structural evidence of functional divergence in human alkaline phosphatases.

ALPI ALPG

2.00e-05464212372831
Pubmed

Inactivation of two mouse alkaline phosphatase genes and establishment of a model of infantile hypophosphatasia.

ALPI ALPG

2.00e-0546429056646
Pubmed

CD44-dependent intracellular and extracellular catabolism of hyaluronic acid by hyaluronidase-1 and -2.

HYAL1 HYAL3

2.00e-05464217170110
Pubmed

Revised nomenclature for the mammalian long-chain acyl-CoA synthetase gene family.

ACSL1 ACSL5

3.32e-05564215292367
Pubmed

Central role of pyrophosphate in acellular cementum formation.

ALPI ALPG

3.32e-05564222675556
Pubmed

Two alkaline phosphatase genes are expressed during early development in the mouse embryo.

ALPI ALPG

3.32e-0556422133555
Pubmed

Identification of acyl-CoA synthetases involved in the mammalian sphingosine 1-phosphate metabolic pathway.

ACSL1 ACSL5

3.32e-05564224269233
Pubmed

Germ cell nuclear antigen (GCNA1) expression does not require a gonadal environment or steroidogenic factor 1: examination of GCNA1 in ectopic germ cells and in Ftz-F1 null mice.

ALPI ALPG

3.32e-0556429291464
Pubmed

Oct4 links multiple epigenetic pathways to the pluripotency network.

DNAJA2 NUMA1 LRRC40 MBD3 TP53BP1

3.72e-0520364522083510
Pubmed

Dissection of the odontoblast differentiation process in vitro by a combination of FGF1, FGF2, and TGFbeta1.

ALPI ALPG

4.98e-05664210878613
Pubmed

Characterization of the murine hyaluronidase gene region reveals complex organization and cotranscription of Hyal1 with downstream genes, Fus2 and Hyal3.

HYAL1 HYAL3

4.98e-05664211929860
Pubmed

Structural basis for the methylation state-specific recognition of histone H4-K20 by 53BP1 and Crb2 in DNA repair.

KDM4A TP53BP1

4.98e-05664217190600
Pubmed

A tumor suppressive coactivator complex of p53 containing ASC-2 and histone H3-lysine-4 methyltransferase MLL3 or its paralogue MLL4.

KMT2B TP53BP1

6.96e-05764219433796
Pubmed

Replacement of Lost Lgr5-Positive Stem Cells through Plasticity of Their Enterocyte-Lineage Daughters.

ALPI ALPG

6.96e-05764226831517
Pubmed

Ontogeny of mRNA expression and activity of long-chain acyl-CoA synthetase (ACSL) isoforms in Mus musculus heart.

ACSL1 ACSL5

6.96e-05764217197235
Pubmed

Skeletal and hematological anomalies in HYAL2-deficient mice: a second type of mucopolysaccharidosis IX?

HYAL1 HYAL3

6.96e-05764218772348
Pubmed

A Runx2/miR-3960/miR-2861 regulatory feedback loop during mouse osteoblast differentiation.

ALPI ALPG

1.19e-04964221324897
Pubmed

Multimodal spatiotemporal transcriptomic resolution of embryonic palate osteogenesis.

ALPI ALPG

1.49e-041064237709732
Pubmed

IFN-λ derived from nonsusceptible enterocytes acts on tuft cells to limit persistent norovirus.

ALPI ALPG

1.81e-041164237703370
Pubmed

A YY1-dependent increase in aerobic metabolism is indispensable for intestinal organogenesis.

ALPI ALPG

2.17e-041264227802136
Pubmed

TNAP limits TGF-β-dependent cardiac and skeletal muscle fibrosis by inactivating the SMAD2/3 transcription factors.

ALPI ALPG

2.17e-041264231289197
Pubmed

Telomere shortening triggers senescence of human cells through a pathway involving ATM, p53, and p21(CIP1), but not p16(INK4a).

TP53BP1 RAD17

2.17e-041264215149599
Pubmed

Ionizing radiation-induced gene modulations, cytokine content changes and telomere shortening in mouse fetuses exhibiting forelimb defects.

TP53BP1 RAD17

2.57e-041364218722365
Pubmed

Gpr158 mediates osteocalcin's regulation of cognition.

GPRC6A GPRC5D

2.99e-041464228851741
Pubmed

General transcription factor TAF4 antagonizes epigenetic silencing by Polycomb to maintain intestine stem cell functions.

ALPI ALPG

2.99e-041464236639541
Pubmed

Tracing the origin of adult intestinal stem cells.

ALPI ALPG

3.93e-041664231092921
Pubmed

Huntingtin regulates mammary stem cell division and differentiation.

NUMA1 STAT5A

5.00e-041864224749073
Pubmed

PTIP associates with MLL3- and MLL4-containing histone H3 lysine 4 methyltransferase complex.

KMT2B TP53BP1

5.00e-041864217500065
Pubmed

HNF4 factors control chromatin accessibility and are redundantly required for maturation of the fetal intestine.

ALPI ALPG

5.59e-041964231345929
Pubmed

Prediction of the coding sequences of mouse homologues of KIAA gene: I. The complete nucleotide sequences of 100 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.

NWD2 AATK KMT2B

5.64e-048764312465718
Pubmed

A multi-factor trafficking site on the spliceosome remodeling enzyme BRR2 recruits C9ORF78 to regulate alternative splicing.

ACSL1 FXR1 NUMA1 SHMT2 LRRC40 WDR41

5.77e-0456064635241646
Pubmed

Dnmt1 is essential to maintain progenitors in the perinatal intestinal epithelium.

ALPI ALPG

6.20e-042064226023099
Pubmed

RNF8- and RNF168-dependent degradation of KDM4A/JMJD2A triggers 53BP1 recruitment to DNA damage sites.

KDM4A TP53BP1

6.20e-042064222373579
Pubmed

Distinct regulatory cascades govern extraocular and pharyngeal arch muscle progenitor cell fates.

ALPI ALPG

6.20e-042064219531352
Pubmed

Broad histone H3K4me3 domains in mouse oocytes modulate maternal-to-zygotic transition.

KMT2B KDM4A

6.84e-042164227626377
Pubmed

Functional roles of Lgr4 and Lgr5 in embryonic gut, kidney and skin development in mice.

ALPI ALPG

8.23e-042364224680895
Pubmed

TFAM is required for maturation of the fetal and adult intestinal epithelium.

ALPI ALPG

1.05e-032664229684311
Pubmed

Recruitment of the Mammalian Histone-modifying EMSY Complex to Target Genes Is Regulated by ZNF131.

KMT2B DNAJA2 KDM4A

1.11e-0311064326841866
Pubmed

HIV-1 Tat protein down-regulates CREB transcription factor expression in PC12 neuronal cells through a phosphatidylinositol 3-kinase/AKT/cyclic nucleoside phosphodiesterase pathway.

PDE1B PIK3C2B

1.14e-032764211156964
Pubmed

Biosynthesis of triacylglycerols.

ACSL1 ACSL5

1.22e-03286428944226
Pubmed

Global analysis of gene expression in the developing brain of Gtf2ird1 knockout mice.

PRUNE2 MRPL16

1.31e-032964221909369
Pubmed

Control of stomach smooth muscle development and intestinal rotation by transcription factor BARX1.

ALPI ALPG

1.40e-033064226057579
Pubmed

Tudor, MBT and chromo domains gauge the degree of lysine methylation.

KDM4A TP53BP1

1.70e-033364216415788
Pubmed

Synergistic drug combinations for cancer identified in a CRISPR screen for pairwise genetic interactions.

PLA2G4C PIK3C2B ACVR1 LARS2

1.70e-0327664428319085
GeneFamilyAlkaline phosphatases

ALPI ALPG

2.71e-0543921072
GeneFamilyAcyl-CoA synthetase family

ACSL1 ACSL5

1.43e-032639240
GeneFamilyTudor domain containing

KDM4A TP53BP1

2.88e-0337392780
ToppCellControl-Myeloid-Alveolar_macrophages|Control / group, cell type (main and fine annotations)

ACSL1 KCNA2 GPCPD1 DDX60L ITGAX

5.80e-061816358d2102c8c86c59a82610f26f90946b290552e666
ToppCellCOVID-19-kidney-Myeloid|COVID-19 / Disease (COVID-19 only), tissue and cell type

ACSL1 VNN1 GPCPD1 DDX60L ITGAX

7.72e-061926350b9d22a222f1201e375f8e55cace9ef939febae4
ToppCell10x_3'_v2v3-Non-neoplastic-Glial-Neuronal-Oligodendrocyte-Oligodendrocyte-B|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

PRUNE2 ENDOD1 AATK PLA2G4C TPRN

8.75e-0619763582b8e22317cad6d3786bd70d91107007c0ccd7cd
ToppCellParenchymal-NucSeq-Immune_Myeloid-Macrophage_alveolar|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

KCNA2 PDE1B GPCPD1 DDX60L ITGAX

8.97e-06198635e125eb8aa57c172e5518874da1bd25998292f5e2
ToppCellCOVID-19-lung-Macrophage_VCANhi_FCN1hi|COVID-19 / Disease (COVID-19 only), tissue and cell type

ACSL1 VNN1 GPCPD1 DDX60L ITGAX

8.97e-06198635ea34096bee852a7e996f097fa279381afa8f86ff
ToppCellParenchymal-NucSeq-Immune_Myeloid-Macrophage_alveolar-Macro_alveolar|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

KCNA2 PDE1B GPCPD1 DDX60L ITGAX

8.97e-061986350baeb8e2c199ff10bb5c829c523546af3c9227c1
ToppCellCaecum-(4)_Monocyte-(40)_Monocyte|Caecum / shred on region, Cell_type, and subtype

ACSL1 PRUNE2 SIGLEC7 VNN1 ITGAX

9.41e-06200635b078058efc51f0ff4d92123b712933b32824c655
ToppCellBronchial-NucSeq-Immune_Myeloid-Macrophage_alveolar|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

ACSL1 KCNA2 GPCPD1 DDX60L ITGAX

9.41e-06200635a443e475e7a10c26a6173d1af961de6219e0e567
ToppCellCaecum-(4)_Monocyte|Caecum / shred on region, Cell_type, and subtype

ACSL1 PRUNE2 SIGLEC7 VNN1 ITGAX

9.41e-062006356bfd6ab395e09087aeedc9a7c9ada1b4b8a26194
ToppCellCaecum-Monocyte-Monocyte|Caecum / Region, Cell class and subclass

ACSL1 PRUNE2 SIGLEC7 VNN1 ITGAX

9.41e-06200635d33619b6c721eae3ebe50fba6b9d31fa99f2248f
ToppCellCaecum-Monocyte|Caecum / Region, Cell class and subclass

ACSL1 PRUNE2 SIGLEC7 VNN1 ITGAX

9.41e-062006359e8d38d024a315512521b349e8ac7caa56219daf
ToppCellBronchial-NucSeq-Immune_Myeloid-Macrophage_alveolar-Macro_alveolar|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

ACSL1 KCNA2 GPCPD1 DDX60L ITGAX

9.41e-06200635ed785a6d08ca2b350dc3307b587eadfb2886d1f9
ToppCellTCGA-Thryoid-Primary_Tumor-Thyroid_Papillary_Carcinoma-Follicular-6|TCGA-Thryoid / Sample_Type by Project: Shred V9

AATK PAFAH2 DUOX2 CC2D2B

4.03e-051356348197d49e697a1fdcd64040ea7a7f0b3ad0a756eb
ToppCellPND01-Epithelial-Epithelial_Airway-Neurosecretory-Secretory|PND01 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

ACSL1 NWD2 PAFAH2 ALPI

7.79e-05160634b4844a8c7755a2b2868019791d8d224154973445
ToppCellPND01-Epithelial-Epithelial_Airway-Neurosecretory-Secretory-Secretory_mature|PND01 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

ACSL1 NWD2 PAFAH2 ALPI

7.79e-0516063401ae730e9d0d05f3277f862f0c09bafb32b89db5
ToppCellPND01-Epithelial-Epithelial_Airway-Neurosecretory|PND01 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

ACSL1 NWD2 PAFAH2 ALPI

7.79e-051606346de9e7be1d860d82d503bfbc779e72f072a6efc3
ToppCelldroplet-Marrow-BM_(NON-STC)-30m-Lymphocytic-plasma_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PRUNE2 KCNA2 ITGAX PLTP

1.03e-041726347295bf3ae21a61dd6bcfa0dfb7a37d0f3e8f94ab
ToppCellfacs-Mammary_Gland-Mammary_Gland-21m-Epithelial-nan|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PRUNE2 ASB16 SPAG8 LARS2

1.10e-041756349a96794df049d8228fea57c1584c160191d36b56
ToppCelldroplet-Lung-nan-18m-Myeloid-Proliferating_Alveolar_Macrophage|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PRUNE2 GALM PLA2G4C ALPG

1.23e-0418063443fd5c498a87bb078d101298b472656f3294686a
ToppCell3'-Adult-LargeIntestine-Epithelial-Tuft-related-Microfold_cell|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

PLA2G4C VNN1 DUOX2 DDX60L

1.28e-04182634b4f347fb684f6840c166d7473f3f56389f69c14b
ToppCellCF-Myeloid-Neutrophil|CF / Disease state, Lineage and Cell class

ACSL1 AATK DDX60L ITGAX

1.31e-04183634da43827952e6fdee2ce94648c316182f272b321c
ToppCelldroplet-Heart-HEART_(LV+RV_ONLY)-30m-Neuronal-cardiac_neuron|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LDHD AATK KCNA2 HYAL3

1.31e-041836348330c39184ce076e1f95fd3725b68af551d89db0
ToppCelldroplet-Lung-nan-21m-Myeloid-alveolar_macrophage|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PRUNE2 GPCPD1 ITGAX ALPG

1.39e-041866348f77e552e613b6e124443c7f6ef5c1316a5ff8db
ToppCelldroplet-Lung-nan-21m-Myeloid-Alveolar_Macrophage|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PRUNE2 GPCPD1 ITGAX ALPG

1.39e-04186634f1aa0c58336d23bcbe52a59e7af954d20085bdb6
ToppCellInfluenza-Influenza_Severe-Myeloid-Neutrophil|Influenza_Severe / Disease, condition lineage and cell class

ACSL1 AATK VNN1 ITGAX

1.39e-041866341dfcec9196d4db76fba3abc74e85885b1fb98b87
ToppCell10x5'-GI_small-bowel-Myeloid_Monocytic-Nonclassical_monocytes|GI_small-bowel / Manually curated celltypes from each tissue

SIGLEC7 ACRBP VNN1 ITGAX

1.39e-04186634a16ecf70271894a842925f232009e2623d16947e
ToppCell3'-Distal_airway-Immune_Myeloid-Myeloid_monocytic-classical_monocyte-Classical_monocytes-Classical_monocytes_L.1.2.0.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

ACSL1 VNN1 DDX60L ITGAX

1.51e-0419063457800d807785b9d539b47945a0a74631f5e88a06
ToppCell3'-Distal_airway-Immune_Myeloid-Myeloid_monocytic-classical_monocyte|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

ACSL1 VNN1 DDX60L ITGAX

1.54e-041916341c7d31684654ca6a046d8cc816af1fdc42369c57
ToppCell3'-Distal_airway-Immune_Myeloid-Myeloid_monocytic-classical_monocyte-Classical_monocytes|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

ACSL1 VNN1 DDX60L ITGAX

1.54e-04191634d60d81d2045c6e624bbc8b17e13a32f7921d969f
ToppCell3'-Broncho-tracheal-Immune_Myeloid-Myeloid_macrophage-elicited_macrophage-Monocyte-derived_macrophage-Monocyte-derived_macrophage_L.1.2.3.1|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

ACSL1 GPCPD1 DDX60L ITGAX

1.54e-041916340b296404ebad0aadb75737f8c0462ec6934fc8bb
ToppCellCOVID-19-kidney-Myeloid|kidney / Disease (COVID-19 only), tissue and cell type

ACSL1 GPCPD1 DDX60L ITGAX

1.57e-04192634441cd1ec171f643b28e1f6f9c04def629cc7391b
ToppCell10x_3'_v2v3-Non-neoplastic-Myeloid-Mono-Mono_hypoxia-E|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

ACSL1 GPCPD1 DDX60L ITGAX

1.60e-041936345703a6faaee82cbad5ce73429bdf1b0f47b37ee0
ToppCellControl-Myeloid-cMonocyte|World / Disease state, Lineage and Cell class

ACSL1 AATK GPCPD1 ITGAX

1.64e-04194634f852f5258617a66a4fbd56d64c7b47272e7b8b60
ToppCellImmune-alveolar_macrophage_(MARCO_positive)|World / Lineage, Cell type, age group and donor

ACSL1 GPCPD1 DDX60L ITGAX

1.67e-04195634f92114ef995e690a3bedc62c89c5fd6773d0d9f7
ToppCellAdult-Immune-alveolar_macrophage_(MARCO_positive)|Adult / Lineage, Cell type, age group and donor

ACSL1 GPCPD1 DDX60L ITGAX

1.67e-0419563455e25f702af19146a161861cfd15f40bbda1dc35
ToppCellmLN-T_cell-gd_T|mLN / Region, Cell class and subclass

ASB16 SCYL3 SPAG8 PLTP

1.74e-041976348ef03bdbd34a874671aebfdbb7111106aa37b2a9
ToppCellsevere-Myeloid-Neutrophils_2|Myeloid / Cohort 2 (Rhapsody WB + PBMC) with disease condition, lineage and cell classs

ACSL1 GALM DDX60L ITGAX

1.74e-04197634c8a90d82170cf20e14aebecddcf7cc0ca56cda87
ToppCellCOVID-19-lung-Macrophage_VCANhi_FCN1hi|lung / Disease (COVID-19 only), tissue and cell type

ACSL1 VNN1 DDX60L ITGAX

1.74e-04197634a0f8a992282a6d64890f5574c7c9741fcb38dadd
ToppCellmLN-(1)_T_cell-(17)_gd_T|mLN / shred on region, Cell_type, and subtype

ASB16 SCYL3 SPAG8 PLTP

1.74e-041976345c781ded147db2f3804ee1f21ef0898c4f354890
ToppCellAdult-Immune-alveolar_macrophage_(MARCO_positive)-D231|Adult / Lineage, Cell type, age group and donor

ACSL1 GPCPD1 DDX60L ITGAX

1.77e-0419863479a415e19cedde13a88f5043d71557363f102322
ToppCellImmune|World / Lineage, Cell type, age group and donor

ACSL1 GPCPD1 DDX60L ITGAX

1.77e-0419863465681b54d13c6997bd90a1c2a12314a80e964fe3
ToppCellsevere-Myeloid-Neutrophils_2|severe / Cohort 2 (Rhapsody WB + PBMC) with disease condition, lineage and cell classs

ACSL1 GALM DDX60L ITGAX

1.77e-04198634636878836678a0715550fa09f2e3dac11c4d73fe
ToppCellCOVID-19_Mild|World / Disease condition and Cell class

ACSL1 GPCPD1 DDX60L ITGAX

1.77e-0419863461ceb2245b6cb58e308b999a61d218c89dbc615e
ToppCellParenchymal-10x3prime_v2-Immune_Myeloid-Macrophage_other-Macro_CHIT1|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations

ACSL1 SIGLEC7 ACRBP ITGAX

1.77e-04198634243109377d62d20c69e9d1fedc252156e90cda1e
ToppCell3'-Parenchyma_lung-Immune_Myeloid-Myeloid_macrophage-alveolar_macrophage-Alveolar_macrophages-Alveolar_macrophages_L.1.6.1.1|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

PDE1B GPCPD1 DDX60L ITGAX

1.80e-041996345b6feacb0ca92c3fc6b327be978320426dcf6f68
ToppCellLPS_anti-TNF-Hematopoietic_Myeloid-Granulocytic_cells-Neutrophils|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type

ACSL1 MRPL16 GPCPD1 ACSL5

1.80e-0419963476aab03a51681f0ce3369887cf71a884b0998ec5
ToppCell5'-Adult-LargeIntestine-Hematopoietic-Myeloid|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

ACSL1 SIGLEC7 ITGAX PLTP

1.80e-04199634a4785c1921a3de18a9190e4d674ede6a90f80004
ToppCellBronchial-10x5prime-Immune_Myeloid-Macrophage_alveolar-Macro_alv_MT|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

ACSL1 GPCPD1 DDX60L ITGAX

1.80e-04199634a1ff1063741f6e5569feb44245785c9f472799b2
ToppCellBAL-Mild-cDC_1|Mild / Compartment, Disease Groups and Clusters

ENDOD1 GALM DDX60L ITGAX

1.80e-04199634c55181bdec8952b54198f0d4c9c5c84265b16572
ToppCellCOVID-19-COVID-19_Mild-Myeloid-Neutrophil|COVID-19_Mild / Disease, condition lineage and cell class

ACSL1 VNN1 DDX60L ITGAX

1.80e-041996349f6b6731186ef399f952a75879eba66fd8ed3494
ToppCellControl_saline-Hematopoietic_Myeloid-Granulocytic_cells-Neutrophils|Control_saline / Treatment groups by lineage, cell group, cell type

ACSL1 SPATA2L MRPL16 VNN1

1.80e-04199634e1240bfcdce76ec018599c50350748f9c7b8fb0e
ToppCellParenchymal-10x5prime-Immune_Myeloid-Macrophage_other-Macro_CHIT1|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

GALM VNN1 ITGAX PLTP

1.80e-04199634f987f48970aec46156b80656e49b9f3604f3758c
ToppCellLPS_anti-TNF-Hematopoietic_Myeloid-Granulocytic_cells|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type

ACSL1 MRPL16 GPCPD1 ACSL5

1.80e-041996347227e6be56e9f333ee143e1418d22de32a4ca66a
ToppCellControl_saline-Hematopoietic_Myeloid-Granulocytic_cells|Control_saline / Treatment groups by lineage, cell group, cell type

ACSL1 SPATA2L MRPL16 VNN1

1.80e-04199634a4d6525e70de39802ff9fdef0d877c4463a6200d
ToppCellTracheal-NucSeq-Immune_Myeloid-Macrophage_other-Macrophage_intermediate|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

SIGLEC7 DCUN1D3 ITGAX PLTP

1.80e-0419963454167894a16e975d0541cbe3e515bcfa183044f6
ToppCellBronchial-NucSeq-Immune_Myeloid-Macrophage_other|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

ACSL1 VNN1 ITGAX PLTP

1.84e-0420063478d75d381cb2b9a4c9eb7c32a07b014eaee39195
ToppCellTracheal-10x3prime_v2-Immune_Myeloid-Macrophage_other-Macrophage_intravascular|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations

ACSL1 SIGLEC7 ITGAX PLTP

1.84e-04200634c210b98a75ab5d899d7278bc9b577f76a0b3970c
ToppCellBrain_organoid-organoid_Tanaka_cellReport-10w-Mesenchymal-Mesoderm|10w / Sample Type, Dataset, Time_group, and Cell type.

CLN8 ENDOD1 WRAP73 ACVR1

1.84e-042006349ef226ebb0a7cdb9431e2fa65faa2a7d67da590d
ToppCellSmart-start-Cell-Wel_seq-Non-neoplastic-Myeloid-TAM-BDM-TAM-BDM_hypoxia/MES-F|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

ACSL1 GALM SIGLEC7 ITGAX

1.84e-042006345f1de1f9305e1784c12d526f6c8bdd7d56229f9b
ComputationalGenes in the cancer module 471.

ACSL1 SHMT2

4.83e-0410362MODULE_471
ComputationalGenes in the cancer module 528.

ACSL1 SHMT2

5.89e-0411362MODULE_528
Diseaseeating disorder, bipolar disorder

FXR1 NALCN

3.52e-0414592EFO_0005203, MONDO_0004985
Diseaseovulation

ACSL1 KDM4A

6.58e-0419592GO_0030728
DiseaseDyslipidemias

VNN1 PLTP

1.05e-0324592C0242339
DiseaseDyslipoproteinemias

VNN1 PLTP

1.05e-0324592C0598784
DiseaseCrohn's disease (is_marker_for)

DUOX2 ALPI

1.54e-0329592DOID:8778 (is_marker_for)
DiseaseArthritis, Experimental

ACSL1 ACSL5

2.92e-0340592C0993582
Diseaseulcerative colitis (is_marker_for)

DUOX2 ALPI

2.92e-0340592DOID:8577 (is_marker_for)
DiseaseArthritis, Adjuvant-Induced

ACSL1 ACSL5

2.92e-0340592C0003865
DiseaseArthritis, Collagen-Induced

ACSL1 ACSL5

2.92e-0340592C0971858
Diseasefree cholesterol to total lipids in IDL percentage

PLTP TP53BP1

3.37e-0343592EFO_0022278
Diseasefree cholesterol to total lipids in very small VLDL percentage

PLTP TP53BP1

3.37e-0343592EFO_0022290
Diseaseprostate cancer (is_marker_for)

KMT2B KDM4A STAT5A

3.79e-03156593DOID:10283 (is_marker_for)
DiseaseAcute Promyelocytic Leukemia

NUMA1 ITGAX

3.84e-0346592C0023487

Protein segments in the cluster

PeptideGeneStartEntry
PDQFIGIFAQNRPEW

ACSL1

146

P33121
ERQTFQPWPERLSNN

ACRBP

161

Q8NEB7
DQQRPNIPNRWFSDP

ACVR1

451

Q04771
QAVQDSPNWEPEVLF

ASB16

326

Q96NS5
FEWANEVRIDPNNPE

CC2D2B

671

Q6DHV5
NNPPVLDQWLNFLTE

DCUN1D3

216

Q8IWE4
FDRQAPDQPWVFQCN

NWD2

806

Q9ULI1
IQVQEWINPVLPDFQ

RAD17

156

O75943
PVSINFWVPVELNQE

ITGAX

966

P20702
AFDLDPAQWGVNVQP

SHMT2

126

P34897
QWTQREPDAVDPVLN

MDGA1

661

Q8NFP4
EERPLPENEFQRQVW

KCNA2

136

P16389
DPQKAVDQPRQLFWE

MBD3

126

O95983
VFENNWQPERQVPFN

FXR1

31

P51114
EESANNQWAPLNPIR

JAG2

1121

Q9Y219
DPRVQDFIPNAWQQE

DDX60L

736

Q5H9U9
WSDLNPNVDPQVLEA

DUOX2

456

Q9NRD8
AEQRWLVEPQIDDPN

ENDOD1

91

O94919
WSLPNRAVEPQLQEE

PLTP

246

P55058
NQPSFQWRQPSLDVE

PDE1B

456

Q01064
SQLWQNRPPNFEAEK

KDM4A

641

O75164
PNNEDWGRQTIPDFV

GDPGP1

16

Q6ZNW5
AQWRQQEPETPESGQ

KMT2B

1541

Q9UMN6
WDQQICFPVQVNRLP

PIK3C2B

686

O00750
QARDCQNPNAFQPWE

GPRC6A

431

Q5T6X5
IPAEEENPAFWNRQA

ALPI

21

P09923
EEPENQTVNIQIWPR

SCYL3

536

Q8IZE3
IPVEEENPDFWNRQA

ALPG

21

P10696
DNDLQPSWQEARAPE

PLA2G4C

176

Q9UP65
IKFDVQFPENNWINP

DNAJA2

331

O60884
LETQNWPDAVNQPRF

GALM

306

Q96C23
PEALQRQWDQVEQDL

GNPTG

181

Q9UJJ9
NWNPQNAVALLPEND

GPCPD1

31

Q9NPB8
FQRQPQWDDPVVCIA

GPRC5D

231

Q9NZD1
PDAVVWPQNVEQVSR

LDHD

66

Q86WU2
AWAQQVFPDLDPQEQ

HYAL3

151

O43820
PDQFVGIFAQNRPEW

ACSL5

131

Q9ULC5
APWQQQQIEDFRQGS

CEP85L

321

Q5SZL2
IDIPEPRVQIWFQNE

DUX1

56

O43812
DWPAPQVEAVAQDQF

HYAL1

161

Q12794
WRINVDIPEEANQNL

LRRC40

56

Q9H9A6
DRQPEWLEEQQGRQF

NUMA1

946

Q14980
PEENQPTNESLQEEW

PAFAH2

151

Q99487
QENELPEAKNRPWIF

FNDC8

221

Q8TC99
DQEERERNNQNPWTF

MRPL16

201

Q9NX20
FNRCEEVQLQPPEVW

TRIM41

386

Q8WV44
QEQPETFWIQRAPQL

SPAG8

406

Q99932
VAWLQQRLAQDEEPP

SPATA2L

196

Q8IUW3
QLWNIQPRQPDPDAD

PRUNE2

1906

Q8WUY3
ENFPVSPELWRQLEQ

SPATA31C2

441

B4DYI2
LLQAWPAVDPEFLQQ

LARS2

821

Q15031
QFCWLQPEQRPTAEE

AATK

376

Q6ZMQ8
APVATNNPAWAVQEE

SIGLEC7

76

Q9Y286
EQLSPVRAFQWDPQQ

WRAP73

371

Q9P2S5
QPWDAIDLDNPQDRA

STAT5A

41

P42229
QLLNPVDWNFAQPEA

CLN8

256

Q9UBY8
PFWNFPEVCQVDEQI

ZNF182

91

P17025
DPEVNWIPCNNRNRF

VNN1

101

O95497
EQRILDWQPRENPFQ

TP53BP1

1856

Q12888
WQEGREFLQDQNPDR

ZNF705EP

66

A8MWA4
WQEQALEQAPREAEP

TPRN

671

Q4KMQ1
PGEIQNWVQEQCPEN

ZSCAN29

71

Q8IWY8
NFWDPSPQLDTQQEI

WDR41

261

Q9HAD4
VPRVWANPRNFNFDN

NALCN

1086

Q8IZF0