Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionprotein kinase C binding

TWF2 TOP2A

4.76e-0466102GO:0005080
GeneOntologyBiologicalProcessmeiosis I

TOP2A SPATA22 PIWIL2

4.10e-05147103GO:0007127
GeneOntologyBiologicalProcessmeiosis I cell cycle process

TOP2A SPATA22 PIWIL2

4.81e-05155103GO:0061982
GeneOntologyBiologicalProcessmeiotic nuclear division

TOP2A SPATA22 PIWIL2

1.76e-04240103GO:0140013
GeneOntologyBiologicalProcessmeiotic cell cycle process

TOP2A SPATA22 PIWIL2

2.43e-04268103GO:1903046
GeneOntologyBiologicalProcesspositive regulation of axon extension

TWF2 PAK1

3.10e-0455102GO:0045773
GeneOntologyBiologicalProcessmeiotic cell cycle

TOP2A SPATA22 PIWIL2

5.32e-04350103GO:0051321
GeneOntologyBiologicalProcessregulation of meiotic cell cycle

SPATA22 PIWIL2

6.88e-0482102GO:0051445
GeneOntologyBiologicalProcessDNA damage response

TOP2A PAK1 SPATA22 ERCC6

7.79e-04959104GO:0006974
GeneOntologyBiologicalProcesspositive regulation of peptidyl-serine phosphorylation

PAK1 ERCC6

1.04e-03101102GO:0033138
GeneOntologyBiologicalProcessregulation of axon extension

TWF2 PAK1

1.10e-03104102GO:0030516
GeneOntologyBiologicalProcessregulation of DNA-templated transcription elongation

ERCC6 ZC3H4

1.12e-03105102GO:0032784
GeneOntologyBiologicalProcesspositive regulation of axonogenesis

TWF2 PAK1

1.32e-03114102GO:0050772
GeneOntologyBiologicalProcessregulation of extent of cell growth

TWF2 PAK1

1.51e-03122102GO:0061387
GeneOntologyBiologicalProcessmeiotic chromosome segregation

TOP2A SPATA22

1.51e-03122102GO:0045132
GeneOntologyBiologicalProcessnuclear division

TOP2A SPATA22 PIWIL2

1.60e-03512103GO:0000280
GeneOntologyBiologicalProcessregulation of circadian rhythm

TOP2A PIWIL2

1.85e-03135102GO:0042752
GeneOntologyBiologicalProcessaxon extension

TWF2 PAK1

1.85e-03135102GO:0048675
GeneOntologyBiologicalProcessregulation of peptidyl-serine phosphorylation

PAK1 ERCC6

1.90e-03137102GO:0033135
GeneOntologyBiologicalProcessDNA-templated transcription elongation

ERCC6 ZC3H4

2.10e-03144102GO:0006354
GeneOntologyBiologicalProcessorganelle fission

TOP2A SPATA22 PIWIL2

2.19e-03571103GO:0048285
GeneOntologyBiologicalProcesspositive regulation of cell development

TWF2 PAK1 RFX3

2.69e-03614103GO:0010720
GeneOntologyBiologicalProcessregulation of organelle organization

TWF2 TOP2A PAK1 PIWIL2

2.73e-031342104GO:0033043
GeneOntologyBiologicalProcesscell cycle process

TOP2A SPATA22 PIWIL2 ERCC6

3.54e-031441104GO:0022402
GeneOntologyBiologicalProcessregulation of axonogenesis

TWF2 PAK1

3.69e-03192102GO:0050770
GeneOntologyBiologicalProcessneuron projection extension

TWF2 PAK1

4.28e-03207102GO:1990138
GeneOntologyBiologicalProcesspositive regulation of cell growth

TWF2 PAK1

4.52e-03213102GO:0030307
GeneOntologyBiologicalProcesschromatin remodeling

PAK1 PIWIL2 ERCC6

4.59e-03741103GO:0006338
GeneOntologyBiologicalProcessfemale gamete generation

TOP2A PIWIL2

4.95e-03223102GO:0007292
GeneOntologyBiologicalProcessregulation of cell size

TWF2 PAK1

5.03e-03225102GO:0008361
GeneOntologyBiologicalProcessregulation of protein polymerization

TWF2 PAK1

5.30e-03231102GO:0032271
GeneOntologyBiologicalProcesspositive regulation of developmental growth

TWF2 PAK1

5.61e-03238102GO:0048639
GeneOntologyCellularComponentactin filament

TWF2 PAK1

2.10e-03146102GO:0005884
GeneOntologyCellularComponentlamellipodium

TWF2 PAK1

5.12e-03230102GO:0030027
GeneOntologyCellularComponentgrowth cone

TWF2 PAK1

5.79e-03245102GO:0030426
GeneOntologyCellularComponentsite of polarized growth

TWF2 PAK1

6.16e-03253102GO:0030427
GeneOntologyCellularComponentmyofibril

TWF2 PAK1

7.14e-03273102GO:0030016
GeneOntologyCellularComponentcontractile muscle fiber

TWF2 PAK1

8.02e-03290102GO:0043292
Pubmed

A probability-based approach for high-throughput protein phosphorylation analysis and site localization.

TOP2A PAK1 ERCC6 ZC3H4

8.47e-0650310416964243
Pubmed

The nuclear import of the small GTPase Rac1 is mediated by the direct interaction with karyopherin alpha2.

TOP2A PAK1

1.14e-051810219961560
Pubmed

Combinatorial targeting of a chromatin complex comprising Dot1L, menin and the tyrosine kinase BAZ1B reveals a new therapeutic vulnerability of endocrine therapy-resistant breast cancer.

TOP2A ERCC6 ZC3H4 SNRPE

6.52e-0584710435850772
Pubmed

Identification of Novel Proteins Co-Purifying with Cockayne Syndrome Group B (CSB) Reveals Potential Roles for CSB in RNA Metabolism and Chromatin Dynamics.

TOP2A ERCC6

6.68e-054310226030138
Pubmed

The RNA binding protein MEX3A promotes tumor progression of breast cancer by post-transcriptional regulation of IGFBP4.

TOP2A ZC3H4 SNRPE

9.84e-0533210337433992
InteractionCSNK2A2 interactions

TOP2A PAK1 PIWIL2 ERCC6 ZC3H4

1.23e-05718105int:CSNK2A2
InteractionCAPN2 interactions

TWF2 TOP2A SNRPE

6.66e-05169103int:CAPN2
InteractionFOXJ1 interactions

TWF2 RFX3

7.16e-0526102int:FOXJ1
ToppCell3'-Airway_Nasal-Epithelial-Airway_epithelium-brush_cell_of_trachebronchial_tree-Tuft|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

TOP2A PIWIL2 SNRPE

5.70e-061651030ae39c9a6d1265d65dc0660924612cfe11e489ec
ToppCell3'-Airway_Nasal-Epithelial-Airway_epithelium-brush_cell_of_trachebronchial_tree-Tuft-Tuft_L.0.7.1.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

TOP2A PIWIL2 SNRPE

5.70e-06165103686cf89077cc7b744a6127de2b34d8c27da8b6c4
ToppCell3'-Airway_Nasal-Epithelial-Airway_epithelium-brush_cell_of_trachebronchial_tree|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

TOP2A PIWIL2 SNRPE

5.70e-06165103a5ed8c331d5551cd8bce50bdc31cb893218317cd
ToppCellDendritic_Cells-HP_01|World / lung cells shred on cell class, cell subclass, sample id

TWF2 EPSTI1 PAK1

7.78e-06183103499da89b4abe7b746e703cd1e5c56f9b1d97ac3c
ToppCellBLOOD--(1)_T_cell-(1)_Activated_T_cells|(1)_T_cell / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)

TWF2 TOP2A EPSTI1

9.26e-061941036a0cbb9d5c5c4effb02dff654c6c3b184026875c
ToppCellGlobus_pallidus-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)-Inhibitory_Neuron.Gad1Gad2.Cadm2_(Cadm2+_state)-|Globus_pallidus / BrainAtlas - Mouse McCarroll V32

SPATA22 PIWIL2

7.56e-0559102bcac768e1e034e27bab7cad3c2bf09a8f0a819ad
ToppCellGlobus_pallidus-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)-Inhibitory_Neuron.Gad1Gad2.Cadm2_(Cadm2+_state)--|Globus_pallidus / BrainAtlas - Mouse McCarroll V32

SPATA22 PIWIL2

7.56e-0559102f9b9464f4d786991aad01b47e2a8fd33f889c2e2
ToppCellGlobus_pallidus-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)-Inhibitory_Neuron.Gad1Gad2.Cadm2_(Cadm2+_state)|Globus_pallidus / BrainAtlas - Mouse McCarroll V32

SPATA22 PIWIL2

7.56e-0559102b2c10c4c0a750d7f49f5a813ab5d103fb07ca76b
ToppCellCOVID-19_Mild-Myeloid_G-immature_Neutrophil|COVID-19_Mild / Disease group, lineage and cell class

TOP2A SPATA22

2.78e-04113102fc3417c379f871a4aec3edef953baaa00755c472
ToppCellPBMC-Mild-Myeloid-Neutrophil-immature_Neutrophil|Mild / Location, Disease Group, Cell group, Cell class (2021.03.09)

TOP2A SPATA22

2.83e-04114102613714fd15ad6d553e63d8538ad53bc1ded6bd6c
ToppCellControl-Developping_Plasmablast|World / disease group and sub_cluster of B and Plasma cells(res = 0.5)

TOP2A SPATA22

3.13e-04120102695dab6b01ad2c33cdcaf92bb9996ff2899ef77e
ToppCell3'_v3-bone_marrow-Lymphocytic_T_CD4-T_CD4/CD8|bone_marrow / Manually curated celltypes from each tissue

SPATA22 PIWIL2

3.18e-0412110219333a660800b583fa27b495c1f7828e6636a257
ToppCellPBMC-Mild-Myeloid-Neutrophil-immature_Neutrophil-Neu_4|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

TOP2A SPATA22

3.45e-041261026cb89754010d64875e115da6c5805efac7a4a82d
ToppCellPBMC-Mild-Myeloid-Neutrophil-immature_Neutrophil-Neu_4|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

TOP2A SPATA22

3.45e-0412610269b2525b92d1c7c35b21cc701f5fa52a9c1b94bb
ToppCellE18.5-samps-Mesenchymal-Matrix_fibroblast-matrix_-_immature_4|E18.5-samps / Age Group, Lineage, Cell class and subclass

TOP2A ERCC6

3.67e-04130102169d88bffd7cd813a484d809defa638ceaca4bcb
ToppCellPND07-Immune-Immune_Myeloid-DC|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

EPSTI1 PAK1

4.69e-04147102bbc52cbea37a38058436e3fc6fc0777f83404524
ToppCellPND01-03-samps-Myeloid-Granulocyte|PND01-03-samps / Age Group, Lineage, Cell class and subclass

TWF2 EPSTI1

4.82e-041491027bdb396de8a1ef27ab0c2aaf1452576f4b0b5561
ToppCellPND01-03-samps-Myeloid-Granulocyte-neutrophil__Lgals3-negative|PND01-03-samps / Age Group, Lineage, Cell class and subclass

TWF2 EPSTI1

4.82e-0414910250f53018e525b3d252caa8bed9e075b1bb1086dd
ToppCell368C-Fibroblasts-Fibroblast-E|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)

TOP2A ERCC6

4.88e-04150102c3ad5fa41eb636a5d691c0268c0f1c32cd0de658
ToppCell368C-Fibroblasts-Fibroblast-E-|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)

TOP2A ERCC6

4.88e-0415010278b8029e71d26f336a46274c8afef3435bf536b9
ToppCelldroplet-Heart-HEART_(ALL_4:4:4:1:1)-30m-Hematologic-leukocyte|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TOP2A EPSTI1

5.01e-04152102bfc7ef4ee26165d18ac4f475a9519e8d52453ba2
ToppCellMyeloid-C_(Monocyte)|World / shred on cell class and cell subclass (v4)

EPSTI1 PAK1

5.01e-041521029145dc014ed7f154c158d454dc2b9754396afcca
ToppCellfacs-Brain_Non-Myeloid-Striatum-24m-Lymphocytic-nan|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TOP2A EPSTI1

5.14e-041541023fa6f77ad2c30ec24b9b904e2732ec5b419dff5b
ToppCellPND07-Immune-Immune_Myeloid-DC-cDC2-cDC2_G2M|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

TOP2A PAK1

5.14e-04154102e3a8a1e63ab345de62bd2e5e54342b00f04ae422
ToppCellfacs-Brain_Non-Myeloid-Striatum-24m-Lymphocytic|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TOP2A EPSTI1

5.14e-04154102ee03b386d28a524084eaf1c0091f7389daa34250
ToppCellMyeloid-A_(Macrophage-Dendritic)|World / shred on cell class and cell subclass (v4)

EPSTI1 PAK1

5.28e-0415610208d5f7fe098b6f2caeeddcc5ed1e34d6a59e697b
ToppCellPND14-Immune-Immune_Myeloid-DC-cDC2-cDC2_prolif|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

TOP2A PAK1

5.28e-041561028349604bd801e20d33770f7d8243598c3756302b
ToppCellPND03-Immune-Immune_Myeloid-Monocytic-Macrophage-iMON-iMON_prolif|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

TOP2A EPSTI1

5.35e-04157102eea53cf8d8a607264e1ee00b7a97c94bcf2ac80d
ToppCellE18.5-Immune-Immune_Myeloid-Monocytic-Macrophage-iMON-iMON_G2M|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

TOP2A EPSTI1

5.35e-04157102904cd98ae85ed6459e0663f077ac462842bf12df
ToppCellPND10-Immune-Immune_Myeloid-DC|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

EPSTI1 PAK1

5.35e-04157102ed387cf06d19e201a2a0dc4f3c796fcf8fa6637a
ToppCellPBMC-Control-Myeloid-cDC-cDC-cDC_1|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

EPSTI1 PAK1

5.41e-04158102216b3f482daa2d0d7fcaf5a8559e3ccbdb8e110d
ToppCellPBMC-Control-Myeloid-cDC-cDC-cDC_1|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

EPSTI1 PAK1

5.41e-041581029712bb8b1bacb8a38c99a22bc2babec5d5160e2a
ToppCellPND07-Immune-Immune_Myeloid-DC-maDC-maDC_mature|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

EPSTI1 PIWIL2

5.55e-0416010201f22cdb2a2f73776b7f91746e95c1850df94235
ToppCellPND07-Immune-Immune_Myeloid-DC-maDC|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

EPSTI1 PIWIL2

5.55e-041601027db30647b596f0c419087e6fabb9b99dcd5bddd4
ToppCellfacs-Lung-EPCAM-3m-Endothelial-Capillary_Type_1_Cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TOP2A PAK1

5.62e-04161102a7e74bc80ac11250e353e5614b19c05793fc2e95
ToppCellPND03-Immune-Immune_Myeloid-DC|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

EPSTI1 PAK1

5.62e-04161102f50e91f8363f20bb7c565aaca4d4961d3fe4b5b5
ToppCellfacs-Kidney-nan-24m|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TWF2 TOP2A

5.69e-04162102f223ea00cf7fbc25e6d5a946ee1ff05f7d4abb06
ToppCellfacs-Liver-Non-hepatocytes-24m-Lymphocytic-T_cell|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TWF2 EPSTI1

5.69e-0416210215d5d31a75e26bcd41919a00300c68e9f00f0002
ToppCell368C-Lymphocytic-CD4_T-cell-Treg_cell_4|CD4_T-cell / Donor, Lineage, Cell class and subclass (all cells)

EPSTI1 RFX3

5.76e-041631029f5facfa1864eb63e2f8022ad7379d9252b7a254
ToppCellfacs-Lung-ENDOMUCIN-18m-Myeloid-myeloid_dendritic_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

EPSTI1 PAK1

5.83e-0416410254f8f11d2fa899005530c08e7a1ee728c7b0799c
ToppCelldroplet-Kidney-nan-18m-Lymphocytic-nan|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

EPSTI1 PIWIL2

5.83e-04164102731b9c7d6f6ecfb14d4a8705e0ddac9fb460d9a8
ToppCellPND10-Immune-Immune_Lymphocytic_T/NK-Lymphocytic_ILC-NK-NK-NK_G2M|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

TOP2A EPSTI1

5.83e-04164102ae09e5aabd1347b865474255e7411c04f63efb3b
ToppCellPND28-Immune-Immune_Lymphocytic_T/NK-Lymphocytic_T-CD8_T-CD8_T_prolif|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

TOP2A SNRPE

5.83e-041641025621c2e3fae84d5a2e4f1595e454bcb3a2b3f93c
ToppCellPND10-Immune-Immune_Lymphocytic_T/NK-Lymphocytic_T-CD8_T-CD8_T_prolif|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

EPSTI1 PIWIL2

5.90e-041651025f606959a060b1ae241217889560c6761ac73bbb
ToppCellCV-Mild-3|Mild / Virus stimulation, Condition and Cluster

TOP2A PAK1

5.97e-041661025599f90fc0e15a3670b03187085eba91228390a2
ToppCellhealthy_donor-Lymphocytic-Plasma_cell-IgM_Plasmablast|healthy_donor / Disease condition, Lineage, Cell class and subclass

TOP2A SPATA22

5.97e-041661022b7b580bec8d9467b0deaf97098065f72dbf2a4f
ToppCellPND14-Immune-Immune_Myeloid-Dendritic|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

TOP2A PAK1

6.12e-041681029b8a74abb83c64f0b5829dcb4275f722c82b45dc
ToppCellPND14-Immune-Immune_Myeloid-Dendritic-cDC1|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

TOP2A PAK1

6.12e-041681024b152b8d0f4a66faf664dfacb7914b18d60ce64a
ToppCellPND03-Immune-Immune_Lymphocytic_T/NK-Lymphocytic_T-CD8_T-CD8_T_prolif|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

TOP2A EPSTI1

6.12e-04168102ade02beb8d663fce4be2aefa10392ab849a4bbe7
ToppCellPND14-Immune-Immune_Myeloid-Dendritic-cDC1-cDC1_G2M|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

TOP2A PAK1

6.12e-04168102c3169ad8f4130ef18777ed86770bb722ffb5db85
ToppCelldroplet-Lung-nan-18m-Myeloid-dendritic_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TOP2A PAK1

6.12e-0416810296f7411474edd673b8d3ee6b8a8bb185c246daaf
ToppCell390C-Myeloid-Dendritic-cDC_proliferating_1|390C / Donor, Lineage, Cell class and subclass (all cells)

TOP2A PAK1

6.12e-041681022082b15fc7935a211f1c61506b305af5501a21ad
ToppCellfacs-Spleen-nan-3m-Lymphocytic-nan|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TOP2A EPSTI1

6.12e-0416810274dc46738f1d0a448df6c9b8288b515d92697792
ToppCelldroplet-Heart-4Chambers-18m-Hematologic|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

EPSTI1 PAK1

6.19e-04169102ea43002e74076aa03bf688c0a76c07117787d4b5
ToppCellPND07-Immune-Immune_Lymphocytic_T/NK-Lymphocytic_T-Treg|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

TOP2A EPSTI1

6.19e-04169102b08567ecfa3f8d83e7990330fc1b27f0bb7e75a1
ToppCellPND03-Immune-Immune_Myeloid-Monocytic-Macrophage-IM-IM_G2M|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

TOP2A PAK1

6.19e-04169102a1efc20e34a81ae32f8d278a5486811ade03ef24
ToppCellfacs-Diaphragm-Limb_Muscle-18m-Myeloid|Diaphragm / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TWF2 TOP2A

6.26e-04170102d582087a983fe20d811d92f0de0458f3cfd71d2b
ToppCellPND03-Immune-Immune_Lymphocytic_T/NK-Lymphocytic_ILC-NK-NK|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

TOP2A EPSTI1

6.26e-04170102da4dde7d0491ccc298cec7474a6a76ff3db36a4c
ToppCellPND10-Immune-Immune_Lymphocytic_T/NK-Lymphocytic_T-CD8_T-CD8_T_G2M|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

TOP2A EPSTI1

6.26e-04170102a0d6466e00bd3dc07f644ba3f87d5b421fd479d5
ToppCellfacs-Diaphragm-Limb_Muscle-18m-Myeloid-macrophage|Diaphragm / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TWF2 TOP2A

6.26e-04170102dfbe7ba11b867a4e10fa915f282a2e5cb2f5fb8c
ToppCellPND14-Immune-Immune_Myeloid-DC-cDC2|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

TOP2A PAK1

6.26e-041701029e94fa0d05abed3438b28296a293767096d517d6
ToppCellPND03-Immune-Immune_Myeloid-Monocytic-Macrophage-iMON-iMON_mature|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

EPSTI1 PAK1

6.33e-0417110292cd1d7ec5bc0a77f81b915d237fac4075ba01e3
ToppCellPND28-Immune-Immune_Myeloid-DC-cDC2-cDC2_mature|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

TOP2A PAK1

6.33e-0417110241f858831a2919a2cacea62f51c2b723eb87b9c4
ToppCellPND14-Immune-Immune_Myeloid-DC|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

TOP2A PAK1

6.33e-041711028772d6349db24de47f089df2032a80345db7177f
ToppCellfacs-Diaphragm-Limb_Muscle-18m-Myeloid-new-cluster|Diaphragm / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TWF2 TOP2A

6.33e-04171102d0d92eb5152410c3b4dd4a3f1dc3cca0e18a85fd
ToppCellPND28-Immune-Immune_Myeloid-DC-cDC2|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

TOP2A PAK1

6.33e-04171102e01bef6d814c0b7bd015c71e20a194e2dec68377
ToppCellE18.5-Epithelial-Epithelial_Alveolar-Epithelial_Alveolar-Sox9_Epi-Sox9_Epi_G2M|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

TOP2A PIWIL2

6.33e-04171102621f9da0bfa09c86fc89fd26919403e94cd56d2b
ToppCellPND07-Immune-Immune_Lymphocytic_T/NK-Lymphocytic_ILC-NK-NK-NK_G2M|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

TOP2A EPSTI1

6.33e-04171102846a9acfff0bf0a9baf65dc07b7d7a9217ed6598
ToppCellfacs-Trachea-18m-Hematologic-myeloid-tracheal_macrophage-macrophage_of_tracheal_l15|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

TWF2 PAK1

6.41e-04172102eaba10a4d4eaab42ad2e2da65ebb20b50edaf815
ToppCelldroplet-Heart-4Chambers-18m-Hematologic-leukocyte|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

EPSTI1 PAK1

6.41e-0417210219ccac3d88382b8b2379d14525b2204c7407cb3b
ToppCelldroplet-Kidney-KIDNEY-1m-Lymphocytic|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TWF2 EPSTI1

6.41e-04172102adf016e5856bc85e7bed58aee09ade483b9dcb00
ToppCellPND03-Immune-Immune_Lymphocytic_T/NK-Lymphocytic_ILC-NK|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

TOP2A EPSTI1

6.41e-041721024bdcf1ae2a1cfba0272c54072e37fb7958904321
ToppCelldroplet-Lung-LUNG-30m-Myeloid-Proliferating_Dendritic|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TOP2A PAK1

6.48e-041731026c9ecf77d2fb0f89100fdd7e4e88f85598278bc7
ToppCellPND03-Immune-Immune_Myeloid-Monocytic-Macrophage-iMON|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

EPSTI1 PAK1

6.48e-041731026d29e142d043dfd1ed442812358ac463b63b5e3f
ToppCelldroplet-Lung-3m-Hematologic-lymphocytic-CD4-positive,_alpha-beta_T_cell-CD4-positive,_alpha-beta_T_cell_l9|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

TWF2 EPSTI1

6.48e-04173102da0f1461643294f92e20b5e456a50211a2780a91
ToppCellfacs-Aorta-Heart-3m-Myeloid|Aorta / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TOP2A PAK1

6.48e-04173102513b4d31bcfb269556c6b4cc389865fb12e52c4f
ToppCelldroplet-Lung-nan-18m-Myeloid-Proliferating_Dendritic|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TOP2A PAK1

6.48e-0417310220a20429aa898097d5ec4880ed64846558b5890f
ToppCellPND14-Immune-Immune_Myeloid-DC-cDC1-cDC1_prolif|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

TOP2A PAK1

6.56e-0417410209b091e24317c3f7bac043f04762a533e30793de
ToppCellfacs-Marrow-B-cells-24m-Lymphocytic-late_pro_B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TOP2A SNRPE

6.56e-04174102c2fc78dd6c440737ded59676961e4c7b923084ce
ToppCellfacs-Marrow-B-cells-24m-Lymphocytic-late_pro-B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TOP2A SNRPE

6.56e-04174102021ebc6ec022b992d7b25333ba0b7416371e041b
ToppCelldroplet-Kidney-nan-3m-Lymphocytic|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TWF2 EPSTI1

6.56e-041741020e541581df2d4249270b28ceded6298329013580
ToppCellPND28-Immune-Immune_Myeloid-DC|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

TOP2A PAK1

6.56e-04174102cfb4947caf7b1a856df246023fc6e5bfcc97ad36
ToppCelldroplet-Lung-18m-Hematologic-myeloid-myeloid_dendritic_cell-proliferating_dendritic|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

TOP2A PAK1

6.63e-04175102a6913f992a1ea20b43e5adeca3ede3a6fda820ad
ToppCellPND03-Immune-Immune_Lymphocytic_T/NK-Lymphocytic_ILC-NK-NK-NK_G2M|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

TOP2A EPSTI1

6.63e-04175102ae7e0448ffd11b8908d0f6d99ff737faf5eca4bf
ToppCelldroplet-Heart-HEART-1m-Hematologic-leukocyte|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

EPSTI1 PAK1

6.63e-04175102a2fed97cf8d28f9936fe791e5e8c43d2430330c9
ToppCelldroplet-Lung-21m-Hematologic-myeloid-myeloid_dendritic_cell-proliferating_dendritic|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

TOP2A PAK1

6.63e-0417510273f25bd54309aed1480ddc44bdab518b17e71f92
ToppCellwk_20-22-Hematologic-Myeloid-Promonocyte-like|wk_20-22 / Celltypes from embryonic and fetal-stage human lung

TOP2A PAK1

6.63e-04175102654299df246debe0a5b12f0d9568eb828bb94bb9
ToppCelldroplet-Heart-HEART-1m-Hematologic|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

EPSTI1 PAK1

6.63e-0417510243b9cfd7c47d57244565c641e57f3256b5900804
ToppCellStriatum-Macroglia-POLYDENDROCYTE-P5-P5_1|Striatum / BrainAtlas - Mouse McCarroll V32

TOP2A SNRPE

6.71e-04176102a84361308e5e96f3a30246cd29e109c321ee65bf
ToppCellStriatum-Macroglia-POLYDENDROCYTE-P5-P5_1-Sox4|Striatum / BrainAtlas - Mouse McCarroll V32

TOP2A SNRPE

6.71e-04176102d70fdc7bc48719776ed1e7c01118385e3a21623f
ToppCelldroplet-Heart-HEART-1m-Hematologic-leukocyte|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

EPSTI1 PAK1

6.71e-041761021df640f88667e2dad30e65279d6d33bba75024c1
ToppCellP15-Epithelial-epithelial_progenitor_cell-epithelial_unknown_3|P15 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

PAK1 ERCC6

6.71e-04176102792f414f5092aba14260b8e16378e793a822498e
ToppCell367C-Myeloid-Dendritic-cDC_proliferating_1|367C / Donor, Lineage, Cell class and subclass (all cells)

TOP2A PAK1

6.78e-04177102ba701d3c90722d8bff70d0fa651899305cdad257
ToppCellfacs-Liver-Liver_non-hepato/SCs-18m-Lymphocytic-mature_NK_T_cell|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TWF2 EPSTI1

6.78e-0417710293379bfd7484812bb45aa27c0324a75be9641685
ToppCellfacs-Diaphragm-Limb_Muscle-18m|Diaphragm / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TWF2 TOP2A

6.86e-0417810240bd605b801d9ae76cffc8f62836092fc2b06812
ToppCellDendritic_Cells-IPF_01|World / lung cells shred on cell class, cell subclass, sample id

EPSTI1 PAK1

6.86e-041781023a28103cf282cc3637d1875a3b4cd7ddf3207687
ToppCellfacs-Liver-Non-hepatocytes-24m-Lymphocytic-mature_NK_T_cell|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TWF2 EPSTI1

6.86e-04178102291ffc52b824e4f59078147eb640ef34e24fb450
ToppCell368C-Myeloid-Dendritic-cDC_proliferating_1|368C / Donor, Lineage, Cell class and subclass (all cells)

TOP2A ERCC6

6.94e-04179102ec69e1dd897414033ba5b007aa82655a79adca6c
ToppCellPND28-Immune-Immune_Myeloid-DC-cDC1-cDC1_prolif|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

TOP2A PAK1

6.94e-041791029dea57494d59abd6e8abf34e31faf53462ea0fa0
ToppCellmild_COVID-19_(asymptomatic)-cDC|World / disease group, cell group and cell class (v2)

EPSTI1 PAK1

7.01e-0418010268d1c867734fb2977b01ac686b20bf602f9a6b72
DrugM-VAC protocol

TOP2A EPSTI1

1.78e-0446102ctd:C044361
Drugm-cresol

TWF2 ERCC6

5.80e-0483102CID000000342
Drugpotassium bromate

SPATA22 ERCC6

9.61e-04107102ctd:C019536
Drugtamibarotene

TWF2 TOP2A PAK1

1.87e-03596103ctd:C061133
DrugAC1NRBJE

TWF2 PAK1

1.92e-03152102CID005288446
Drugtrichostatin A, Streptomyces sp.; Down 200; 1uM; PC3; HT_HG-U133A

TWF2 ZC3H4

2.71e-031811027077_DN
DrugPhenoxybenzamine hydrochloride [63-92-3]; Down 200; 11.8uM; MCF7; HT_HG-U133A

TWF2 TOP2A

2.92e-031881026451_DN
DrugMethotrexate [59-05-2]; Down 200; 8.8uM; HL60; HG-U133A

TOP2A ZC3H4

2.95e-031891022041_DN
DrugAdenosine Triphosphate

TOP2A ERCC6

3.08e-03193102ctd:D000255
DrugVerapamyl hydrochloride [152-11-4]; Down 200; 8.2uM; HL60; HG-U133A

TOP2A ZC3H4

3.11e-031941022009_DN
Drug(-) -Levobunolol hydrochloride [27912-14-7]; Down 200; 12.2uM; HL60; HT_HG-U133A

PAK1 ERCC6

3.11e-031941023015_DN
DrugNeostigmine bromide [114-80-7]; Down 200; 13.2uM; HL60; HT_HG-U133A

PAK1 ERCC6

3.14e-031951022432_DN
Drugestradiol; Down 200; 0.01uM; MCF7; HT_HG-U133A

RFX3 ERCC6

3.20e-031971025905_DN
DrugPargyline hydrochloride [306-07-0]; Down 200; 20.4uM; MCF7; HT_HG-U133A

TWF2 ERCC6

3.20e-031971022265_DN
DrugHexamethonium dibromide dihydrate [55-97-0]; Up 200; 10uM; PC3; HT_HG-U133A

PAK1 PIWIL2

3.30e-032001026620_UP
Diseasenephroblastoma (is_marker_for)

TOP2A PAK1

5.77e-0534102DOID:2154 (is_marker_for)
Diseaselung adenocarcinoma (is_marker_for)

ERCC6 SNRPE

3.64e-0485102DOID:3910 (is_marker_for)
DiseaseNeurodevelopmental Disorders

PAK1 ZC3H4

4.35e-0493102C1535926
Diseaseprostate cancer (is_marker_for)

TOP2A SNRPE

1.22e-03156102DOID:10283 (is_marker_for)
DiseaseMalignant neoplasm of breast

TOP2A PAK1 ERCC6

4.76e-031074103C0006142
Diseasehip circumference

TOP2A ZC3H4

5.54e-03338102EFO_0005093
DiseaseMammary Neoplasms, Human

TOP2A PAK1

1.29e-02525102C1257931
DiseaseMammary Carcinoma, Human

TOP2A PAK1

1.29e-02525102C4704874
DiseaseMammary Neoplasms

TOP2A PAK1

1.30e-02527102C1458155
DiseaseBreast Carcinoma

TOP2A PAK1

1.36e-02538102C0678222

Protein segments in the cluster

PeptideGeneStartEntry
KKIQVQQPNMIKVYN

ERCC6

911

P0DP91
QKQQLQLMQSKYKQK

EPSTI1

121

Q96J88
VAIKQMNLQQQPKKE

PAK1

296

Q13153
KPNFQQNQYKKQMLD

SPATA22

201

Q8NHS9
QQPMQQKQRYKPMQK

RFX3

276

P48380
ENYQPKMVVFVVQKK

PIWIL2

841

Q8TC59
QGQKVQKVMVQPINL

SNRPE

6

P62304
SPQQLQQQDMYNKKI

ZC3H4

566

Q9UPT8
LQPVNENMQVNKIKK

TOP2A

6

P11388
QQLKQKMVNYIQMKL

TWF2

191

Q6IBS0