Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	scaffold protein binding	SHANK1 VIM GRIK2 LRP4 KCNQ1 NOS1	5.77e-05	93	144	6	GO:0097110
GeneOntologyBiologicalProcess	behavior	SHANK1 CACNB4 OPN4 SERPINF1 GRIK2 ACSS2 ITGA5 SPECC1 OPRK1 USP2 TTBK1 ADRB1 NRXN1 ANKRD11 NAV2 KCNQ1 CCL11 OLFM2 NOS1 UNC79	3.54e-06	891	143	20	GO:0007610
GeneOntologyCellularComponent	cell body	VIM OPN4 HTR3A SERPINF1 DNER DAXX GRIK2 OPRK1 NRP1 CKB UNC5A CNNM1 TTBK1 NRXN1 KCNC1 KCNC3 LRP4 MAST1 KCNQ1 SLC24A1	3.90e-06	929	140	20	GO:0044297
GeneOntologyCellularComponent	neuronal cell body	OPN4 HTR3A SERPINF1 DNER GRIK2 OPRK1 NRP1 CKB UNC5A CNNM1 TTBK1 NRXN1 KCNC1 KCNC3 LRP4 MAST1 KCNQ1 SLC24A1	1.22e-05	835	140	18	GO:0043025
GeneOntologyCellularComponent	somatodendritic compartment	SHANK1 KIF21B OPN4 HTR3A NTF3 SERPINF1 DNER GRIK2 OPRK1 NRP1 CKB UNC5A CNNM1 TTBK1 NRXN1 KCNC1 KCNC3 LRP4 MAST1 KCNQ1 SLC24A1 NOS1	2.24e-05	1228	140	22	GO:0036477
GeneOntologyCellularComponent	synaptic membrane	SHANK1 HTR3A ANXA1 GRIK2 ITGA5 OPRK1 NRP1 NRXN1 TENM3 KCNC1 KCNC3 LRP4 OLFM2	1.53e-04	583	140	13	GO:0097060
GeneOntologyCellularComponent	cation channel complex	CACNB4 DPP10 HTR3A GRIK2 KCNC1 KCNC3 PKD1 KCNQ1	1.89e-04	235	140	8	GO:0034703
GeneOntologyCellularComponent	axon	KIF21B VIM OPN4 HTR3A NTF3 ROR1 SERPINF1 GRIK2 OPRK1 NRP1 NRXN1 TENM3 KCNC1 KCNC3 MAST1 NOS1	3.16e-04	891	140	16	GO:0030424
GeneOntologyCellularComponent	protein complex involved in cell adhesion	ITGA2B ITGA5 ITGA7 NRXN1	6.59e-04	59	140	4	GO:0098636
GeneOntologyCellularComponent	potassium channel complex	DPP10 GRIK2 KCNC1 KCNC3 KCNQ1	6.78e-04	104	140	5	GO:0034705
GeneOntologyCellularComponent	cell-substrate junction	NPHS1 VIM ANXA1 AMBRA1 ITGA2B ITGA5 ITGA7 NRP1 LMO7 TNS1	8.18e-04	443	140	10	GO:0030055
GeneOntologyCellularComponent	anchoring junction	NPHS1 VIM DSG3 ANXA1 FRMPD2 MTSS1 AMBRA1 ITGA2B ITGA5 ITGA7 CLDN12 NRP1 NRXN1 LMO7 PLEKHA7 TNS1	8.47e-04	976	140	16	GO:0070161
GeneOntologyCellularComponent	monoatomic ion channel complex	CACNB4 DPP10 HTR3A GRIK2 KCNC1 KCNC3 PKD1 KCNQ1 OLFM2	1.03e-03	378	140	9	GO:0034702
GeneOntologyCellularComponent	mast cell granule	ANXA1 CXCR2	1.21e-03	8	140	2	GO:0042629
GeneOntologyCellularComponent	cell surface	ANXA1 ROR1 MUC16 ITGA2B ITGA5 ITGA7 NRP1 CSF2RB NRXN1 KCNC1 LMO7 PKD1 TMPRSS11D LRP4 SLC24A1 TNS1 CXCR2	1.24e-03	1111	140	17	GO:0009986
GeneOntologyCellularComponent	integrin complex	ITGA2B ITGA5 ITGA7	1.26e-03	32	140	3	GO:0008305
GeneOntologyCellularComponent	basement membrane	NPHS1 SERPINF1 TGFBI LOXL2 EGFLAM	1.39e-03	122	140	5	GO:0005604
GeneOntologyCellularComponent	postsynaptic membrane	SHANK1 HTR3A GRIK2 ITGA5 OPRK1 NRP1 KCNC1 KCNC3 OLFM2	1.66e-03	405	140	9	GO:0045211
GeneOntologyCellularComponent	calyx of Held	KCNC1 KCNC3 NOS1	1.79e-03	36	140	3	GO:0044305
GeneOntologyCellularComponent	dendrite	SHANK1 KIF21B OPN4 NTF3 DNER GRIK2 OPRK1 CKB CNNM1 KCNC1 KCNC3 LRP4 MAST1 NOS1	1.88e-03	858	140	14	GO:0030425
GeneOntologyCellularComponent	dendritic tree	SHANK1 KIF21B OPN4 NTF3 DNER GRIK2 OPRK1 CKB CNNM1 KCNC1 KCNC3 LRP4 MAST1 NOS1	1.92e-03	860	140	14	GO:0097447
GeneOntologyCellularComponent	filtration diaphragm	NPHS1 NRXN1	2.35e-03	11	140	2	GO:0036056
GeneOntologyCellularComponent	slit diaphragm	NPHS1 NRXN1	2.35e-03	11	140	2	GO:0036057
GeneOntologyCellularComponent	focal adhesion	NPHS1 VIM ANXA1 AMBRA1 ITGA2B ITGA5 NRP1 LMO7 TNS1	2.52e-03	431	140	9	GO:0005925
GeneOntologyCellularComponent	presynaptic membrane	HTR3A GRIK2 OPRK1 NRXN1 TENM3 KCNC1 KCNC3	2.68e-03	277	140	7	GO:0042734
GeneOntologyCellularComponent	distal axon	KIF21B ROR1 GRIK2 OPRK1 NRP1 NRXN1 KCNC1 KCNC3 NOS1	2.68e-03	435	140	9	GO:0150034
GeneOntologyCellularComponent	axon terminus	ROR1 GRIK2 OPRK1 KCNC1 KCNC3 NOS1	2.95e-03	210	140	6	GO:0043679
GeneOntologyCellularComponent	neuronal cell body membrane	UNC5A KCNC1 KCNC3	2.98e-03	43	140	3	GO:0032809
GeneOntologyCellularComponent	voltage-gated potassium channel complex	DPP10 KCNC1 KCNC3 KCNQ1	3.28e-03	91	140	4	GO:0008076
GeneOntologyCellularComponent	cell body membrane	UNC5A KCNC1 KCNC3	3.84e-03	47	140	3	GO:0044298
Domain	MIM/ABBA	MTSS1 MTSS2	5.82e-05	2	143	2	IPR030127
Domain	Integrin_alpha	ITGA2B ITGA5 ITGA7	6.93e-05	11	143	3	PF00357
Domain	I-BAR_dom	ARHGAP42 MTSS1 MTSS2	1.19e-04	13	143	3	IPR013606
Domain	Integrin_alpha_C_CS	ITGA2B ITGA5 ITGA7	2.29e-04	16	143	3	IPR018184
Domain	Integrin_alpha-2	ITGA2B ITGA5 ITGA7	3.30e-04	18	143	3	IPR013649
Domain	INTEGRIN_ALPHA	ITGA2B ITGA5 ITGA7	3.30e-04	18	143	3	PS00242
Domain	Integrin_alpha2	ITGA2B ITGA5 ITGA7	3.30e-04	18	143	3	PF08441
Domain	Integrin_alpha	ITGA2B ITGA5 ITGA7	3.30e-04	18	143	3	IPR000413
Domain	ATP-gua_PtransN	CKB CKM	3.46e-04	4	143	2	PF02807
Domain	PHOSPHAGEN_KINASE	CKB CKM	3.46e-04	4	143	2	PS00112
Domain	ATP-gua_Ptrans	CKB CKM	3.46e-04	4	143	2	PF00217
Domain	-	CKB CKM	3.46e-04	4	143	2	1.10.135.10
Domain	K_chnl_volt-dep_Kv3	KCNC1 KCNC3	3.46e-04	4	143	2	IPR003974
Domain	ATP-guanido_PTrfase_N	CKB CKM	3.46e-04	4	143	2	IPR022413
Domain	ATP-guanido_PTrfase_AS	CKB CKM	3.46e-04	4	143	2	IPR022415
Domain	ATP-guanido_PTrfase_cat	CKB CKM	3.46e-04	4	143	2	IPR022414
Domain	PHOSPHAGEN_KINASE_N	CKB CKM	3.46e-04	4	143	2	PS51509
Domain	PHOSPHAGEN_KINASE_C	CKB CKM	3.46e-04	4	143	2	PS51510
Domain	Int_alpha	ITGA2B ITGA5 ITGA7	3.89e-04	19	143	3	SM00191
Domain	Int_alpha_beta-p	ITGA2B ITGA5 ITGA7	3.89e-04	19	143	3	IPR013519
Domain	EGF	DNER SNED1 NRXN1 TIE1 LRP4 EGFLAM	4.21e-04	126	143	6	PF00008
Domain	KIND_dom	SPIRE2 FRMPD2	5.73e-04	5	143	2	IPR011019
Domain	KIND	SPIRE2 FRMPD2	5.73e-04	5	143	2	SM00750
Domain	ATP-guanido_PTrfase	CKB CKM	5.73e-04	5	143	2	IPR000749
Domain	KIND	SPIRE2 FRMPD2	5.73e-04	5	143	2	PS51377
Domain	IMD	MTSS1 MTSS2	5.73e-04	5	143	2	PS51338
Domain	FG_GAP	ITGA2B ITGA5 ITGA7	6.08e-04	22	143	3	PS51470
Domain	PDZ	SHANK1 FRMPD2 SIPA1 LMO7 MAST1 NOS1	7.62e-04	141	143	6	PF00595
Domain	WH2	SPIRE2 MTSS1 MTSS2	7.91e-04	24	143	3	PS51082
Domain	FG-GAP	ITGA2B ITGA5 ITGA7	7.91e-04	24	143	3	PF01839
Domain	FG-GAP	ITGA2B ITGA5 ITGA7	7.91e-04	24	143	3	IPR013517
Domain	Gln_synth/guanido_kin_cat_dom	CKB CKM	8.56e-04	6	143	2	IPR014746
Domain	IMD	MTSS1 MTSS2	8.56e-04	6	143	2	PF08397
Domain	-	CKB CKM	8.56e-04	6	143	2	3.30.590.10
Domain	Integrin_dom	ITGA2B ITGA5 ITGA7	8.93e-04	25	143	3	IPR032695
Domain	PDZ	SHANK1 FRMPD2 SIPA1 LMO7 MAST1 NOS1	9.81e-04	148	143	6	SM00228
Domain	-	SHANK1 FRMPD2 SIPA1 LMO7 MAST1 NOS1	1.05e-03	150	143	6	2.30.42.10
Domain	PDZ	SHANK1 FRMPD2 SIPA1 LMO7 MAST1 NOS1	1.09e-03	151	143	6	PS50106
Domain	PDZ	SHANK1 FRMPD2 SIPA1 LMO7 MAST1 NOS1	1.13e-03	152	143	6	IPR001478
Domain	CH	SPECC1 LMO7 NAV3 NAV2	1.55e-03	65	143	4	SM00033
Domain	7TM_GPCR_Srsx	OR51A4 OR51A2 OPN4 OPRK1 ADRB1	1.71e-03	112	143	5	SM01381
Domain	VG_K_chnl	KCNC1 KCNC3 KCNQ1	2.03e-03	33	143	3	IPR028325
Domain	Death	UNC5A NFKB2 DTHD1	2.03e-03	33	143	3	PF00531
Domain	CH	SPECC1 LMO7 NAV3 NAV2	2.04e-03	70	143	4	PF00307
Pubmed	Prediction of the coding sequences of mouse homologues of KIAA gene: III. the complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.	KIF21B NCAPD3 BRPF3 MTSS1 HECTD4 AMBRA1 TELO2 LMO7 PAN2 NAV2 LRP4 DEPDC5 PPIP5K2 CFAP97	5.77e-08	529	146	14	14621295
Pubmed	Identification of new putative susceptibility genes for several psychiatric disorders by association analysis of regulatory and non-synonymous SNPs of 306 genes involved in neurotransmission and neurodevelopment.	HTR3A NTF3 PLCD4 GRIK2 OPRK1 NRP1 GNRHR2 ADRB1 NRXN1 NOS1	6.19e-07	300	146	10	19086053
Pubmed	The identification of myocilin-associated proteins in the human trabecular meshwork.	VIM SERPINF1 ITGA7 CKM PKLR	9.13e-07	42	146	5	16289162
Pubmed	Prediction of the coding sequences of unidentified human genes. X. The complete sequences of 100 new cDNA clones from brain which can code for large proteins in vitro.	HECTD4 TELO2 SOCS5 PAN2 DEPDC5 SLC24A1	4.77e-06	102	146	6	9734811
Pubmed	Spatiotemporal profile of postsynaptic interactomes integrates components of complex brain disorders.	SHANK1 KIF21B VIM CACNB4 HECTD4 GRIK2 SIPA1 FAM171A2 NRXN1 UBR5 TNS1 NOS1 UNC79 NUP153 MTSS2	1.41e-05	963	146	15	28671696
Pubmed	Presynaptic Kv3 channels are required for fast and slow endocytosis of synaptic vesicles.	KCNC1 KCNC3	1.75e-05	2	146	2	33508244
Pubmed	Motor dysfunction and altered synaptic transmission at the parallel fiber-Purkinje cell synapse in mice lacking potassium channels Kv3.1 and Kv3.3.	KCNC1 KCNC3	1.75e-05	2	146	2	12930807
Pubmed	Kv3 potassium channels control the duration of different arousal states by distinct stochastic and clock-like mechanisms.	KCNC1 KCNC3	1.75e-05	2	146	2	16553620
Pubmed	Neuropilin-1/GIPC1 signaling regulates alpha5beta1 integrin traffic and function in endothelial cells.	ITGA5 NRP1	1.75e-05	2	146	2	19175293
Pubmed	Myocardial creatine kinase expression after left ventricular assist device support.	CKB CKM	1.75e-05	2	146	2	12039490
Pubmed	Creatine kinase transcript accumulation: effect of nerve during muscle development.	CKB CKM	1.75e-05	2	146	2	10417818
Pubmed	Kv3.3 subunits control presynaptic action potential waveform and neurotransmitter release at a central excitatory synapse.	KCNC1 KCNC3	1.75e-05	2	146	2	35510987
Pubmed	Mesenchymal stem cell-derived extracellular vesicles exert pro-angiogenic and pro-lymphangiogenic effects in ischemic tissues by transferring various microRNAs and proteins including ITGa5 and NRP1.	ITGA5 NRP1	1.75e-05	2	146	2	38347587
Pubmed	Creatine kinase activity in normal and Duchenne muscular dystrophy fibroblasts.	CKB CKM	1.75e-05	2	146	2	7057800
Pubmed	Behavioral motor dysfunction in Kv3-type potassium channel-deficient mice.	KCNC1 KCNC3	1.75e-05	2	146	2	16923152
Pubmed	Subcellular localization of the voltage-gated potassium channels Kv3.1b and Kv3.3 in the cerebellar dentate nucleus of glutamic acid decarboxylase 67-green fluorescent protein transgenic mice.	KCNC1 KCNC3	1.75e-05	2	146	2	18682278
Pubmed	A genome-wide association study in American Indians implicates DNER as a susceptibility locus for type 2 diabetes.	DNER KCNQ1	1.75e-05	2	146	2	24101674
Pubmed	The effects of prior calcium channel blocker therapy on creatine kinase-MB levels after percutaneous coronary interventions.	CKB CKM	1.75e-05	2	146	2	19337554
Pubmed	Dissimilarity in the folding of human cytosolic creatine kinase isoenzymes.	CKB CKM	1.75e-05	2	146	2	21931810
Pubmed	Ablation of Kv3.1 and Kv3.3 potassium channels disrupts thalamocortical oscillations in vitro and in vivo.	KCNC1 KCNC3	1.75e-05	2	146	2	18495891
Pubmed	Increased motor drive and sleep loss in mice lacking Kv3-type potassium channels.	KCNC1 KCNC3	1.75e-05	2	146	2	15005717
Pubmed	Subunit conformation and dynamics in a heterodimeric protein: studies of the hybrid isozyme of creatine kinase.	CKB CKM	1.75e-05	2	146	2	9748661
Pubmed	Exploring the role of the active site cysteine in human muscle creatine kinase.	CKB CKM	1.75e-05	2	146	2	16981706
Pubmed	Creatine kinase in non-muscle tissues and cells.	CKB CKM	1.75e-05	2	146	2	7808454
Pubmed	Approaching the multifaceted nature of energy metabolism: inactivation of the cytosolic creatine kinases via homologous recombination in mouse embryonic stem cells.	CKB CKM	1.75e-05	2	146	2	7808458
Pubmed	Spinocerebellar ataxia-13 Kv3.3 potassium channels: arginine-to-histidine mutations affect both functional and protein expression on the cell surface.	KCNC1 KCNC3	1.75e-05	2	146	2	23734863
Pubmed	Diagnostic significance of total creatine kinase and its isoform in tubal ectopic pregnancy.	CKB CKM	1.75e-05	2	146	2	23876027
Pubmed	Rescue of motor coordination by Purkinje cell-targeted restoration of Kv3.3 channels in Kcnc3-null mice requires Kcnc1.	KCNC1 KCNC3	1.75e-05	2	146	2	20016089
Pubmed	Purkinje-cell-restricted restoration of Kv3.3 function restores complex spikes and rescues motor coordination in Kcnc3 mutants.	KCNC1 KCNC3	1.75e-05	2	146	2	18448641
Pubmed	Identification of residues of functional importance within the central turn motifs present in the cytoplasmic tails of integrin alphaIIb and alphaV subunits.	ITGA2B ITGA5	1.75e-05	2	146	2	18328539
Pubmed	Allele-dependent changes of olivocerebellar circuit properties in the absence of the voltage-gated potassium channels Kv3.1 and Kv3.3.	KCNC1 KCNC3	1.75e-05	2	146	2	15217387
Pubmed	Alcohol hypersensitivity, increased locomotion, and spontaneous myoclonus in mice lacking the potassium channels Kv3.1 and Kv3.3.	KCNC1 KCNC3	1.75e-05	2	146	2	11517255
Pubmed	Missing-in-metastasis MIM/MTSS1 promotes actin assembly at intercellular junctions and is required for integrity of kidney epithelia.	NPHS1 MTSS1 MTSS2	2.01e-05	13	146	3	21406566
Pubmed	Identification of a novel family of G protein-coupled receptor associated sorting proteins.	OPRK1 ADRB1 GPRASP2	2.55e-05	14	146	3	15086532
Pubmed	Conserved molecular signatures of neurogenesis in the hippocampal subgranular zone of rodents and primates.	VIM DPP10 HTR3A DNER CKB BMP3 KCNC1 NOS1 MTSS2	3.23e-05	376	146	9	24154525
Pubmed	Construction of expression-ready cDNA clones for KIAA genes: manual curation of 330 KIAA cDNA clones.	DNAJC16 TOGARAM1 NRXN1 UBR5 LMO7 NAV2 MINAR1	4.89e-05	225	146	7	12168954
Pubmed	Down regulation of the PEDF gene in human lens epithelium cells changed the expression of proteins vimentin and alphaB-crystallin.	VIM SERPINF1	5.24e-05	3	146	2	20104255
Pubmed	miRNAs regulating the expressions of NTF3, GNG2 and ITGA7 are involved in the pathogenesis of abdominal aortic aneurysm in mice.	NTF3 ITGA7	5.24e-05	3	146	2	33655887
Pubmed	Adrenergic regulation of a key cardiac potassium channel can contribute to atrial fibrillation: evidence from an I Ks transgenic mouse.	ADRB1 KCNQ1	5.24e-05	3	146	2	18006587
Pubmed	Nitric oxide is an activity-dependent regulator of target neuron intrinsic excitability.	KCNC1 NOS1	5.24e-05	3	146	2	21791288
Pubmed	Cloning and characterization of ADAMTS-14, a novel ADAMTS displaying high homology with ADAMTS-2 and ADAMTS-3.	ADAMTS3 ADAMTS14	5.24e-05	3	146	2	11741898
Pubmed	Human U87 astrocytoma cell invasion induced by interaction of βig-h3 with integrin α5β1 involves calpain-2.	ITGA5 TGFBI	5.24e-05	3	146	2	22629380
Pubmed	LOXL2 promotes oncogenic progression in alveolar rhabdomyosarcoma independently of its catalytic activity.	VIM LOXL2	5.24e-05	3	146	2	31911079
Pubmed	Neural control of heart rate is an arrhythmia risk modifier in long QT syndrome.	ADRB1 KCNQ1	5.24e-05	3	146	2	18308161
Pubmed	Predictive value of cardiac troponin-I compared to creatine kinase-myocardial band for the assessment of infarct size as measured by cardiac magnetic resonance.	CKB CKM	5.24e-05	3	146	2	20588136
Pubmed	N-glycosylation of the mammalian dipeptidyl aminopeptidase-like protein 10 (DPP10) regulates trafficking and interaction with Kv4 channels.	DPP10 KCNC1	5.24e-05	3	146	2	22387313
Pubmed	The procollagen N-proteinases ADAMTS2, 3 and 14 in pathophysiology.	ADAMTS3 ADAMTS14	5.24e-05	3	146	2	25863161
Pubmed	LOXL2 status correlates with tumor stage and regulates integrin levels to promote tumor progression in ccRCC.	ITGA5 LOXL2	5.24e-05	3	146	2	25092917
Pubmed	Kv3 channels contribute to the delayed rectifier current in small cultured mouse dorsal root ganglion neurons.	KCNC1 KCNC3	5.24e-05	3	146	2	22673617
Pubmed	Roles for GP IIb/IIIa and αvβ3 integrins in MDA-MB-231 cell invasion and shear flow-induced cancer cell mechanotransduction.	ITGA2B ITGA5	5.24e-05	3	146	2	24176823
Pubmed	[Differential expression of USP2, USP14 and UBE4A between ovarian serous cystadenocarcinoma and adjacent normal tissues].	UBE4A USP2	5.24e-05	3	146	2	17553343
Pubmed	Clinical utility of circulating matrix metalloproteinase-7 (MMP-7), CC chemokine ligand 18 (CCL18) and CC chemokine ligand 11 (CCL11) as markers for diagnosis of epithelial ovarian cancer.	MUC16 CCL11	5.24e-05	3	146	2	19937162
Pubmed	Neuron navigator: a human gene family with homology to unc-53, a cell guidance gene from Caenorhabditis elegans.	NAV3 NAV2	5.24e-05	3	146	2	12079279
Pubmed	Sensory deficits in mice hypomorphic for a mammalian homologue of unc-53.	NAV3 NAV2	5.24e-05	3	146	2	15158073
Pubmed	Divalent cations differentially regulate integrin alphaIIb cytoplasmic tail binding to beta3 and to calcium- and integrin-binding protein.	ITGA2B ITGA5	5.24e-05	3	146	2	10358085
Pubmed	Pore membrane and/or filament interacting like protein 1 (POMFIL1) is predominantly expressed in the nervous system and encodes different protein isoforms.	NAV3 NAV2	5.24e-05	3	146	2	12062803
Pubmed	The muscle-specific laminin receptor alpha7 beta1 integrin negatively regulates alpha5 beta1 fibronectin receptor function.	ITGA5 ITGA7	5.24e-05	3	146	2	9925758
Pubmed	Increasing creatine kinase activity protects against hypoxia / reoxygenation injury but not against anthracycline toxicity in vitro.	CKB CKM	5.24e-05	3	146	2	28806770
Pubmed	A central chaperone-like role for 14-3-3 proteins in human cells.	VIM SPIRE2 SPECC1 TESK1 FAM171A2 LMO7 ANKRD11 NAV2 PPIP5K2 PLEKHA7 CFAP97 DMTN MTSS2	7.40e-05	861	146	13	36931259
Pubmed	IgSF8: a developmentally and functionally regulated cell adhesion molecule in olfactory sensory neuron axons and synapses.	ITGA2B ITGA5 ITGA7	7.84e-05	20	146	3	22687584
Pubmed	Harnessing host enhancers of SARS-CoV-2 entry as novel targets for antiviral therapy.	ANXA1 ROR1 NRP1 TGFBI	8.61e-05	55	146	4	38945485
Pubmed	Loss of Zeb2 in mesenchyme-derived nephrons causes primary glomerulocystic disease.	NPHS1 GLIS3 PKD1	9.12e-05	21	146	3	27591083
Pubmed	Defining the human deubiquitinating enzyme interaction landscape.	GALK1 ANXA1 AMBRA1 TUBGCP2 CKB YOD1 USP2 UBR5 PKLR PAN2 PLEKHA7 GPRASP2 ELL NUP153	9.13e-05	1005	146	14	19615732
Pubmed	CRL4AMBRA1 targets Elongin C for ubiquitination and degradation to modulate CRL5 signaling.	GALK1 AMBRA1 DCAF10 UBR5 GPRASP2	9.58e-05	108	146	5	30166453
Pubmed	Brain expression of Kv3 subunits during development, adulthood and aging and in a murine model of Alzheimer's disease.	KCNC1 KCNC3	1.04e-04	4	146	2	21912965
Pubmed	Stimulation of peripheral kappa opioid receptors inhibits inflammatory hyperalgesia via activation of the PI3Kγ/AKT/nNOS/NO signaling pathway.	OPRK1 NOS1	1.04e-04	4	146	2	22316281
Pubmed	ABBA regulates plasma-membrane and actin dynamics to promote radial glia extension.	MTSS1 MTSS2	1.04e-04	4	146	2	18413296
Pubmed	KLC3 Regulates Ciliary Trafficking and Cyst Progression in CILK1 Deficiency-Related Polycystic Kidney Disease.	CILK1 PKD1	1.04e-04	4	146	2	35961787
Pubmed	Identification of a novel binding site for platelet integrins alpha IIb beta 3 (GPIIbIIIa) and alpha 5 beta 1 in the gamma C-domain of fibrinogen.	ITGA2B ITGA5	1.04e-04	4	146	2	12799374
Pubmed	A novel actin bundling/filopodium-forming domain conserved in insulin receptor tyrosine kinase substrate p53 and missing in metastasis protein.	MTSS1 MTSS2	1.04e-04	4	146	2	14752106
Pubmed	Deubiquitylating enzyme USP2 counteracts Nedd4-2-mediated downregulation of KCNQ1 potassium channels.	USP2 KCNQ1	1.04e-04	4	146	2	22024150
Pubmed	Localization of Shaw-related K+ channel genes on mouse and human chromosomes.	KCNC1 KCNC3	1.04e-04	4	146	2	8111118
Pubmed	Expression of ADAMTS-2, -3, -13, and -14 in culprit coronary lesions in patients with acute myocardial infarction or stable angina.	ADAMTS3 ADAMTS14	1.04e-04	4	146	2	22205175
Pubmed	Involvement of integrins alpha(3)beta(1) and alpha(5)beta(1) and glycoprotein IIb in megakaryocyte-induced osteoblast proliferation.	ITGA2B ITGA5	1.04e-04	4	146	2	20052668
Pubmed	CircGLIS3 promotes gastric cancer progression by regulating the miR-1343-3p/PGK1 pathway and inhibiting vimentin phosphorylation.	VIM GLIS3	1.04e-04	4	146	2	38459513
Pubmed	Calcium Integrin Binding Protein Associates with Integrins αVβ3 and αIIbβ3 Independent of β3 Activation Motifs.	ITGA2B ITGA5	1.04e-04	4	146	2	24163826
Pubmed	Placental defects in alpha7 integrin null mice.	ITGA5 ITGA7	1.04e-04	4	146	2	17904217
Pubmed	A novel dual signaling axis for NSP 5a3a induced apoptosis in head and neck carcinoma.	DAXX SPECC1	1.04e-04	4	146	2	22170762
Pubmed	Role of serum myeloperoxidase, CPK, CK-MB, and cTnI tests in early diagnosis of myocardial ischemia during ERCP.	CKB CKM	1.04e-04	4	146	2	25141318
Pubmed	Comparative Label-Free Mass Spectrometric Analysis of Mildly versus Severely Affected mdx Mouse Skeletal Muscles Identifies Annexin, Lamin, and Vimentin as Universal Dystrophic Markers.	VIM ANXA1	1.04e-04	4	146	2	26102067
Pubmed	Chr21 protein-protein interactions: enrichment in proteins involved in intellectual disability, autism, and late-onset Alzheimer's disease.	SHANK1 VIM COG2 PDE7A RBL2 HECTD4 DNER SPECC1 UBE4A USP2 LMO7 PKD1 NAV3 LRP4 MAST1 GPRASP2	1.05e-04	1285	146	16	35914814
Pubmed	Estrogen-dependent uterine secretion of osteopontin activates blastocyst adhesion competence.	ITGA2B ITGA5 ITGA7	1.21e-04	23	146	3	23152823
Pubmed	USP37 is a SNAI1 deubiquitinase.	YOD1 USP2 PAN2	1.37e-04	24	146	3	31911859
Pubmed	SR protein kinases promote splicing of nonconsensus introns.	RPL34 TOGARAM1 ITGA5 PPIG GSE1 DCAF10 LMO7 NUP153	1.52e-04	361	146	8	26167880
Pubmed	Candidate gene polymorphisms for ischemic stroke.	ITGA2B LTB CCL11 PARP12	1.56e-04	64	146	4	19729601
Pubmed	NDP52 interacts with mitochondrial RNA poly(A) polymerase to promote mitophagy.	VIM SPECC1 LMO7	1.56e-04	25	146	3	30309841
Pubmed	Comprehensive proteomic analysis of interphase and mitotic 14-3-3-binding proteins.	VIM ANXA1 HECTD4 CKM IARS2 LMO7	1.58e-04	190	146	6	15161933
Pubmed	Polycystin-1 interacts with intermediate filaments.	VIM PKD1	1.74e-04	5	146	2	11581269
Pubmed	Group IVA cytosolic phospholipase A2 (cPLA2alpha) and integrin alphaIIbbeta3 reinforce each other's functions during alphaIIbbeta3 signaling in platelets.	VIM ITGA2B	1.74e-04	5	146	2	18840708
Pubmed	Identification and characterization of novel candidate compounds targeting 6- and 7-transmembrane μ-opioid receptor isoforms.	OPRK1 ADRB1	1.74e-04	5	146	2	33782947
Pubmed	Neutrophil-derived microvesicles enter cartilage and protect the joint in inflammatory arthritis.	ANXA1 CXCR2	1.74e-04	5	146	2	26606969
Pubmed	A proteomics approach to isolating neuropilin-dependent α5 integrin trafficking pathways: neuropilin 1 and 2 co-traffic α5 integrin through endosomal p120RasGAP to promote polarised fibronectin fibrillogenesis in endothelial cells.	ITGA5 NRP1	1.74e-04	5	146	2	38789481
Pubmed	Isolation and characterization of the gene and cDNA encoding human mitochondrial creatine kinase.	CKB CKM	1.74e-04	5	146	2	2914937
Pubmed	Developmental regulation of creatine kinase gene expression by myogenic factors in embryonic mouse and chick skeletal muscle.	CKB CKM	1.74e-04	5	146	2	1668275
Pubmed	Basic amino-acid side chains regulate transmembrane integrin signalling.	ITGA2B ITGA5	1.74e-04	5	146	2	22178926
Pubmed	Ephrin-As, Eph receptors and integrin α3 interact and colocalise at membrane protrusions of U251MG glioblastoma cells.	VIM TOGARAM1 ITGA2B CKM LOXL2 PKLR	1.92e-04	197	146	6	23686814
Pubmed	Perlecan regulates pericyte dynamics in the maintenance and repair of the blood-brain barrier.	ITGA2B ITGA5 ITGA7	1.97e-04	27	146	3	31541017
Pubmed	A BioID-Derived Proximity Interactome for SARS-CoV-2 Proteins.	GALK1 DNER CKB CNNM1 TENM3 UBR5 TELO2 NFKB2 LRP4 HERC1 PLEKHA7	2.40e-04	719	146	11	35337019
Pubmed	CLEC16A interacts with retromer and TRIM27, and its loss impairs endosomal trafficking and neurodevelopment.	COG2 NCAPD3 GALK1 DNAJC16 AMBRA1 MARCHF7 TUBGCP2 IARS2 DCAF10 TELO2	2.55e-04	606	146	10	36538041
Pubmed	Integrins take partners: cross-talk between integrins and other membrane receptors.	ITGA2B ITGA5	2.60e-04	6	146	2	9789327
GeneFamily	CD molecules\|Integrin alpha subunits	ITGA2B ITGA5 ITGA7	1.12e-04	18	96	3	1160
GeneFamily	PDZ domain containing	SHANK1 FRMPD2 SIPA1 LMO7 MAST1 NOS1	1.59e-04	152	96	6	1220
GeneFamily	I-BAR domain containing	MTSS1 MTSS2	2.76e-04	5	96	2	1287
GeneFamily	Potassium voltage-gated channels	KCNC1 KCNC3 KCNQ1	1.24e-03	40	96	3	274
GeneFamily	Fibronectin type III domain containing	NPHS1 SNED1 CSF2RB TIE1 EGFLAM	1.63e-03	160	96	5	555
ToppCell	mLN-(5)_Dendritic_cell\|mLN / shred on region, Cell_type, and subtype	NTF3 SERPINF1 OPRK1 NRP1 CKB TGFBI CSF2RB LOXL2 ZC3H12C	1.95e-08	199	145	9	4feecf533e29a1a558f1018a2e8f7bfa7b9d3864
ToppCell	mLN-Dendritic_cell\|mLN / Region, Cell class and subclass	NTF3 SERPINF1 OPRK1 NRP1 CKB TGFBI CSF2RB LOXL2 ZC3H12C	1.95e-08	199	145	9	597412beae1324b9c43ca2bb96c4cb645c19f3e9
ToppCell	COVID-19-kidney-Fibroblast-1\|COVID-19 / Disease (COVID-19 only), tissue and cell type	TRIB2 NTF3 GLIS3 NRP1 TENM3 LOXL2 NAV2 TNS1	1.88e-07	187	145	8	76bfe8c42430a230a8bdf299575c444fb7780f24
ToppCell	Smart-seq2-spleen_(Smart-seq2)-myeloid-myeloid_granulocytic\|spleen_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type	CACNB4 TMC7 MUC16 OPRK1 TTBK1 LRP4 NOS1 CXCR2	2.59e-07	195	145	8	19853c654ac64b3ae3bc99841c6cb29c8aaba85c
ToppCell	COVID-19-kidney-Fibroblast-2\|COVID-19 / Disease (COVID-19 only), tissue and cell type	ARHGAP42 TRIB2 NTF3 GLIS3 NRP1 TENM3 LOXL2 NAV2	2.59e-07	195	145	8	3d62ce1c696f47d4d7eb0c5bb0eec2c24b122bb2
ToppCell	Smart-seq2-spleen_(Smart-seq2)-myeloid-myeloid_granulocytic-neutrophil\|spleen_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type	CACNB4 TMC7 MUC16 OPRK1 TTBK1 LRP4 NOS1 CXCR2	2.59e-07	195	145	8	d3755929ebbbf5e3afde44281e9056ddb614a291
ToppCell	Smart-start-Cell-Wel_seq-Non-neoplastic-Glial-Neuronal-OPC-OPC-G\|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	DPP10 MTSS1 DNER PLLP NRXN1 LRP4 NOS1 UNC79	3.02e-07	199	145	8	19a97e27a4758e794ce7246d295e112b47931a48
ToppCell	5'-GW_trimst-1.5-SmallIntestine-Mesenchymal-fibroblastic-Stromal_3_(C7+)\|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	VIM ANXA1 ROR1 SERPINF1 NRP1 TENM3 NAV3 OLFM2	3.02e-07	199	145	8	83383d9ae4f501754fd3da0215ce6f0e3c70562c
ToppCell	LPS_IL1RA_TNF-Hematopoietic_Erythro-Megakary-Erythro-Mega\|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type	SLC25A42 HECTD4 DEPDC1 ITGA2B SPECC1 YOD1 PKLR DMTN	3.02e-07	199	145	8	2b754670fe77c2301afcdcfc73a1e52cc0cd1de3
ToppCell	LPS_IL1RA_TNF-Hematopoietic_Erythro-Megakary\|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type	SLC25A42 HECTD4 DEPDC1 ITGA2B SPECC1 YOD1 PKLR DMTN	3.02e-07	199	145	8	f894c88ecc7fd0edca28587801fa59352d10f750
ToppCell	PND03-Endothelial-Endothelial_blood-vessel-Microvascular_EC-CAP2-CAP2_prolif\|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	TRIB2 NRP1 PLLP ADRB1 NRXN1 SOCS5 METTL15	1.34e-06	168	145	7	c7021748003e5949f7caf7b3291c5bad294948c1
ToppCell	T_cells-Resident_memory_CD8+_T_cells\|T_cells / Immune cells in Kidney/Urine in Lupus Nephritis	VIM NUGGC PDE7A RBL2 SPECC1 ADRB1 SLA2	2.28e-06	182	145	7	111d434b89902ec11fb07f41b8ee1a98f3991b61
ToppCell	facs-Heart-RA-18m-Mesenchymal-valve_cell\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TRIB2 ITGA7 SPECC1 NRXN1 LOXL2 EGFLAM OLFM2	2.36e-06	183	145	7	2f0dcc65ad4d90ef946919b4462280fdd20c5ea0
ToppCell	facs-Heart-RA-18m-Mesenchymal-valve_cell\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TRIB2 ITGA7 SPECC1 NRXN1 LOXL2 EGFLAM OLFM2	2.36e-06	183	145	7	0f02136359787bd78146617990968baa47a65d86
ToppCell	5'-Adult-LargeIntestine-Mesenchymal-Pericytes-Pericyte\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	ARHGAP42 OPN4 ITGA7 TGFBI LOXL2 EGFLAM OLFM2	2.63e-06	186	145	7	0c477016c1b539b3086a8066c3c6443f08c222a3
ToppCell	(2)_Fibroblasts-(20)_Fibro-1\|World / Cell class and subclass of bone marrow stroma cells in homeostatis	VIM ANXA1 SERPINF1 ITGA2B TGFBI SNED1 CCL11	2.82e-06	188	145	7	409a7b69d02e87084ca955e3fe6c77230dee8861
ToppCell	3'-Adult-LargeIntestine-Mesenchymal-fibroblastic-mLN_Stroma_(FMO2+)\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	VIM SERPINF1 DNER RNF175 TGFBI EGFLAM CCL11	3.24e-06	192	145	7	11867f30f0b420c18cb0b34d3990237aa737a0e8
ToppCell	droplet-Lung-LUNG-1m-Endothelial-Capillary_Aerocyte_endothelial_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TRIB2 NRP1 PLLP TIE1 LMO7 KCNQ1 EGFLAM	3.24e-06	192	145	7	f094ac378e635cf5820e8a8b7a0152073a51ceae
ToppCell	E16.5-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_vascular\|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	ARHGAP42 TRIB2 ITGA7 CKB NRXN1 LOXL2 CCL11	3.36e-06	193	145	7	7386fadc13a437f3b0c99b5d116cd3c5f893529c
ToppCell	facs-Lung-nan-3m\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ROR1 SERPINF1 TGFBI SNED1 SIDT2 LOXL2 CCL11	3.72e-06	196	145	7	787c6cd92035e0b1108c2c086c42a229016e476b
ToppCell	facs-Lung-nan\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ROR1 SERPINF1 TGFBI SNED1 SIDT2 LOXL2 CCL11	3.72e-06	196	145	7	b05f77f3990b662682ffeaf0e4c2fb190e0a6e65
ToppCell	5'-GW_trimst-1.5-LargeIntestine-Mesenchymal-fibroblastic\|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	VIM ANXA1 SERPINF1 NRP1 NRXN1 NAV3 OLFM2	3.84e-06	197	145	7	05e303fff86db31f7b742324c64980eb2b9cff9a
ToppCell	5'-GW_trimst-1.5-LargeIntestine-Mesenchymal-fibroblastic-Stromal_3_(C7+)\|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	VIM ANXA1 SERPINF1 NRP1 NRXN1 NAV3 OLFM2	3.97e-06	198	145	7	cfe2d52b19a1b4c2c2076fa1d5a69baf21a49623
ToppCell	Tracheal-10x5prime-Stromal-Peri/Epineurial_-NAF_epineurial\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	ROR1 ITGA7 SNED1 BMP3 EGFLAM ADAMTS14 NOS1	4.11e-06	199	145	7	fbec5c034576cb1adaf05f6f97cc5525d19e0c1b
ToppCell	Skin-Mesangial\|Skin / Skin and Kidney Cells in Lupus Nephritis Patients.	VIM SPECC1 OPRK1 TTBK1 KCNC3 EGFLAM TNS1	4.11e-06	199	145	7	bcb78838a91cc7828680fb413fbacdb091c5fac0
ToppCell	(2)_Fibroblasts-(24)_Fibro-5\|World / Cell class and subclass of bone marrow stroma cells in homeostatis	VIM ANXA1 SERPINF1 CKB TGFBI USP2 LOXL2	4.11e-06	199	145	7	6c0354f57883330c685a8d9d5d3014ace7eca584
ToppCell	Tracheal-NucSeq-Stromal-Peri/Epineurial_\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	ARHGAP42 VIM TRIB2 ROR1 MTSS1 ITGA7 SNED1	4.11e-06	199	145	7	3835452e4848d7f7dd8651c17b746b271ef39688
ToppCell	LPS_anti-TNF-Hematopoietic_Erythro-Megakary\|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type	SLC25A42 HECTD4 ITGA2B SPECC1 YOD1 PKLR DMTN	4.11e-06	199	145	7	6c174dbcc25b980f10a3d1dfe39e613acac73bb6
ToppCell	LPS_anti-TNF-Hematopoietic_Erythro-Megakary-Erythro-Mega\|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type	SLC25A42 HECTD4 ITGA2B SPECC1 YOD1 PKLR DMTN	4.11e-06	199	145	7	284ee9632413f6404fc0b0c7c393ad813db834f2
ToppCell	Tracheal-NucSeq-Stromal\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	VIM NRP1 SNED1 TENM3 NAV3 NAV2 TNS1	4.25e-06	200	145	7	c318d14bd6fd6f42c597eb55ac9e2f48008aeb9b
ToppCell	Tracheal-NucSeq-Stromal-Fibroblastic-Fibro_adventitial\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	VIM SERPINF1 ITGA5 NRP1 SNED1 NAV3 NAV2	4.25e-06	200	145	7	0c25d56292b9e5fefa4521b72635449be1ffd6fe
ToppCell	LPS_IL1RA_TNF-Hematopoietic_Erythro-Megakary-Erythro-Mega-Erythroid\|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type	SLC25A42 HECTD4 DEPDC1 SPECC1 YOD1 PKLR DMTN	4.25e-06	200	145	7	f100edfd2b3b742458cbbf34de9c403c4d272d3c
ToppCell	Smart-start-Cell-Wel_seq-Non-neoplastic-Myeloid-TAM-BDM-TAM-BDM_hypoxia/MES-G\|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	VIM ANXA1 TUBGCP2 ITGA5 NRP1 TGFBI TNS1	4.25e-06	200	145	7	851c57187db8bc91a393655bca5f13e787a723d4
ToppCell	BAL-Mild-Myeloid-cDC-cDC-cDC_4\|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)	CACNB4 MUC16 SIPA1 SPECC1 NFKB2 CCDC144A	9.49e-06	149	145	6	a85a051e0d82430160967e72fa04b55f43e84513
ToppCell	BAL-Mild-Myeloid-cDC-cDC-cDC_4\|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	CACNB4 MUC16 SIPA1 SPECC1 NFKB2 CCDC144A	9.86e-06	150	145	6	7a381f5ae94eba5eb60dcbf83416b4eb18c279ea
ToppCell	droplet-Kidney-nan-18m-Lymphocytic-lymphocyte\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	VIM ANXA1 TGFBI CSF2RB SLC24A1 CXCR2	1.15e-05	154	145	6	ad6cfd7fc02f4201863dc8e12e353395c86c5fdb
ToppCell	E16.5-samps-Mesenchymal-Myofibroblast-Migrating_MyoFibroblast\|E16.5-samps / Age Group, Lineage, Cell class and subclass	OPN4 NTF3 CKB TGFBI LOXL2 ADAMTS14	1.19e-05	155	145	6	1882fa5fd25f77d6e3ac47b613f6fb3c67d8e50c
ToppCell	Children_(3_yrs)-Epithelial-basal_cell-D032\|Children_(3_yrs) / Lineage, Cell type, age group and donor	ARHGAP42 CACNB4 NTF3 SERPINF1 NRXN1 WDR87	1.28e-05	157	145	6	6ee2692f705bdd93ba523dffaf2f0cd921b47e28
ToppCell	droplet-Kidney-nan-18m-Lymphocytic-CD45\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	VIM ANXA1 TGFBI CSF2RB SLC24A1 CXCR2	1.33e-05	158	145	6	e0b862e4b9ebaa12869640b5d18d5fa852861bef
ToppCell	3'-GW_trimst-1.5-SmallIntestine-Mesenchymal-Pericytes-angiogenic_pericyte\|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	NUGGC ANXA1 ITGA7 SPECC1 NRP1 EGFLAM	1.69e-05	165	145	6	369d77a80d6401e85ea3121ab5a252f67d5f157e
ToppCell	5'-GW_trimst-2-LargeIntestine-Hematopoietic-T_cells-Activated_T\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	PDE7A ANXA1 RBL2 SLA2 LTB DTHD1	1.75e-05	166	145	6	fb2cfbf1d0a0f1950dd24c08ba00ebd64b06ceb4
ToppCell	facs-Marrow-T_cells-18m-Myeloid\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ANXA1 CKB TGFBI ADRB1 CSF2RB CXCR2	1.75e-05	166	145	6	fab4da2537904ad114218f720e18a600f14a00a1
ToppCell	facs-Marrow-B-cells-24m-Lymphocytic-CD4-positive,_alpha-beta_T_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PLCD4 ITGA7 NRP1 CKB LMO7 NOS1	1.81e-05	167	145	6	713899690e4acd9d259645e363c26983d6ef3022
ToppCell	facs-Marrow-B-cells-24m-Lymphocytic-BM_CD4_T_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PLCD4 ITGA7 NRP1 CKB LMO7 NOS1	1.81e-05	167	145	6	d30b96c39da3dd02500443877a4eb3500e26802c
ToppCell	Posterior_cortex-Neuronal-Inhibitory\|Posterior_cortex / BrainAtlas - Mouse McCarroll V32	HTR3A MTSS1 DNER KCNC1 NOS1 MTSS2	1.81e-05	167	145	6	9a84f45345c75f2c8ff38a04245aadee2a26a240
ToppCell	primary_visual_cortex-Neuronal-glutamatergic_neuron-L6_IT-L6_IT_VISp_Col23a1_Adamts2\|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	ADAMTS3 ROR1 TUBGCP2 UNC5A BMP3 GSE1	1.88e-05	168	145	6	3fe432267656aff81b6d92c18d1b6fc0cde73d6a
ToppCell	systemic_lupus_erythematosus-treated-Hematopoietic\|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex	SHANK1 RPL34 RBL2 KCNC1 PKLR LTB	2.01e-05	170	145	6	9a18756e6721980d4b6c37bb52ddfe93ca79c5ab
ToppCell	systemic_lupus_erythematosus-treated-Hematopoietic-Progen\|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex	SHANK1 RPL34 RBL2 KCNC1 PKLR LTB	2.07e-05	171	145	6	09b3fa120f63c411f8a0dd6bd230a9720ce83fb1
ToppCell	nucseq-Epithelial-Epithelial_Neuro-Secretory-PNEC\|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	DPP10 GRIK2 CKB NRXN1 NOS1 UNC79	2.07e-05	171	145	6	f4321133190a3df9d31f5d4021a464d3840145f1
ToppCell	nucseq-Epithelial-Epithelial_Neuro-Secretory-PNEC-PNEC\|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	DPP10 GRIK2 CKB NRXN1 NOS1 UNC79	2.07e-05	171	145	6	ed4fb6c84579d99df33de5f8f928c3cd2f3d3d72
ToppCell	systemic_lupus_erythematosus-treated-Hematopoietic-Progen-female\|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex	SHANK1 RPL34 RBL2 KCNC1 PKLR LTB	2.07e-05	171	145	6	61d622153b91702ef21b0efc7b9581e592b7ccea
ToppCell	Mid-temporal_gyrus_(MTG)-Neuronal-Glutamatergic_Excit-Glut_E_(THEMIS)-Glut_D_(IT_RORB_THEMIS_LINC00507)_6-Exc_L5-6_THEMIS_TMEM233\|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	ADAMTS3 ITGA7 TBC1D26 OPRK1 SNED1 TENM3	2.07e-05	171	145	6	fdd96c6fe850bd10e1e0d0f18c4401f8348b7d2c
ToppCell	facs-Heart-LV-18m-Mesenchymal-valve_cell\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TRIB2 NTF3 ROR1 ITGA7 LOXL2 EGFLAM	2.21e-05	173	145	6	d78397e65e997ddb995111a810f0e2a4f67d0765
ToppCell	facs-Lung-18m-Hematologic-lymphocytic-immature_innate_lymphoid_cell-Ly6g5b+_T\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	ACSS2 CKM KCNC1 SLA2 LTB UNC79	2.21e-05	173	145	6	0a355386210a13927ea29b10b64cb059459952d4
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell-Distal_Convoluted_Tubule_Cell_Type_1\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	CACNB4 DNER PLCD4 OPRK1 ALPK3 NOS1	2.21e-05	173	145	6	4bc6d93716f093b460c8b047199db8cab5fea720
ToppCell	facs-Lung-18m-Hematologic-lymphocytic-immature_innate_lymphoid_cell\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	ACSS2 CKM KCNC1 SLA2 LTB UNC79	2.21e-05	173	145	6	3678b300cad4effd7f49bfb043305ed512693848
ToppCell	facs-Heart-LV-18m-Mesenchymal-valve_cell\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TRIB2 NTF3 ROR1 ITGA7 LOXL2 EGFLAM	2.21e-05	173	145	6	3c852ffe22f4a5b632463086b08c669310684e80
ToppCell	3'-GW_trimst-2-LargeIntestine-Hematopoietic-Myeloid-pDC\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	HTR3A SERPINF1 CSF2RB KCNC3 SLA2 LTB	2.29e-05	174	145	6	4120656e6d6cf5435a248326b5fdbdc7b22137af
ToppCell	facs-Lung-EPCAM-18m-Lymphocytic-Ly6g5b+_T\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ACSS2 CKM KCNC1 SLA2 LTB UNC79	2.29e-05	174	145	6	d9489c4196d103ead8cb6279492bbe563a222e45
ToppCell	Control-Myeloid-MoAM2,_CCL18\|Control / Condition, Lineage and Cell class	SERPINF1 MTSS1 TGFBI ZC3H12C ADAMTS14 TNS1	2.29e-05	174	145	6	4c64ff5666812fb4efa440ba4faeca51d916d68e
ToppCell	facs-Lung-EPCAM-18m-Lymphocytic-T_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ACSS2 CKM KCNC1 SLA2 LTB UNC79	2.29e-05	174	145	6	aae7ab9df5a78716034ddfd5bd47adc69912d624
ToppCell	COVID-19-lung-RBC\|COVID-19 / Disease (COVID-19 only), tissue and cell type	ITGA2B SPECC1 YOD1 SLA2 HERC1 DMTN	2.36e-05	175	145	6	4c35292ad2ac712ba7516f27dd6eac6ba8fdd163
ToppCell	droplet-Fat-SCAT-30m-Mesenchymal-nan\|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SPIRE2 SERPINF1 CKM PLLP ALPK3 LRP4	2.60e-05	178	145	6	5cf12927f0756c4d8a289fe4308d736382e6212e
ToppCell	Anterior_Cingulate_gyrus_(CgG)-Neuronal-Glutamatergic_Excit-Glut_E_(THEMIS)-Glut_D_(IT_RORB_THEMIS_LINC00507)_6-Exc_L5-6_THEMIS_TMEM233\|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	ADAMTS3 ITGA7 NRP1 SNED1 TENM3 CCDC144A	2.68e-05	179	145	6	747a32460b257fffca30527b56a74720eb9c12e4
ToppCell	Anterior_Cingulate_gyrus_(CgG)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_D_(IT_RORB_THEMIS_LINC00507)_3-Exc_L2-3_LINC00507_RPL9P17\|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	OPN4 ADAMTS3 TGFBI SNED1 UNC5A CCDC144A	2.68e-05	179	145	6	9ba8693fba2175bca9ff9735cc04e657abeb9084
ToppCell	E15.5-Mesenchymal-myocytic_cell-vascular_associated_smooth_muscle_cell\|E15.5 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	VIM TRIB2 ITGA7 NRP1 CNNM1 EGFLAM	2.77e-05	180	145	6	38035cf2c6fbc443ea10ca7e942572715ed572da
ToppCell	facs-Lung-EPCAM-18m-Endothelial-endothelial_cell_of_lung\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	NUGGC SIPA1 CKM ADRB1 TIE1 KCNQ1	2.77e-05	180	145	6	082c6116e0bbba8d9a3a82d14af55bdc8990c8c0
ToppCell	facs-Lung-EPCAM-18m-Endothelial-Capillary_endothelial_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	NUGGC SIPA1 CKM ADRB1 TIE1 KCNQ1	2.77e-05	180	145	6	53043d764fad9ac33ee40e356e562e759931adef
ToppCell	facs-Brain_Non-Myeloid-Cerebellum_-18m-Epithelial-neuroepithelial_cell\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ANXA1 SERPINF1 DEPDC1 TGFBI BMP3 LOXL2	2.85e-05	181	145	6	c26d3cbbc592299786d79d1b15fc6bead2aafb9a
ToppCell	primary_auditory_cortex_(A1C)-Neuronal-Glutamatergic_Excit-Glut_E_(THEMIS)-Glut_D_(IT_RORB_THEMIS_LINC00507)_6-Exc_L6_THEMIS_LINC00343\|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	ADAMTS3 SERPINF1 OPRK1 SNED1 TENM3 CCDC144A	2.85e-05	181	145	6	9de2f2cc5f02e0ca599c9e0d2cb1e1e4b5aac112
ToppCell	PND01-03-samps-Mesenchymal-Myofibroblast\|PND01-03-samps / Age Group, Lineage, Cell class and subclass	SERPINF1 TGFBI TENM3 LOXL2 ADAMTS14 GPRASP2	2.94e-05	182	145	6	812dac35b9aa05be48258082e007f6c00e7b4dd8
ToppCell	Hippocampus-Neuronal-Inhibitory\|Hippocampus / BrainAtlas - Mouse McCarroll V32	HTR3A MTSS1 DNER KCNC1 UBR5 MTSS2	2.94e-05	182	145	6	b54ae650c04dfd0759c5f5e752b9bf684dd36516
ToppCell	5'-GW_trimst-1-SmallIntestine-Endothelial-blood_vessel_EC-venous_capillary\|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	ITGA5 NRP1 TIE1 NAV3 KCNQ1 LTB	3.13e-05	184	145	6	97e97de52daaff8840f4ee76a94ba5e3f79de7ce
ToppCell	P28-Endothelial\|P28 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	VIM SIPA1 NRP1 PLLP ADRB1 TIE1	3.13e-05	184	145	6	b056411f499866097f4322999cfd1e57a3927b78
ToppCell	droplet-Lung-30m-Hematologic-lymphocytic-immature_innate_lymphoid_cell\|30m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	CKB KCNC1 SLA2 LTB UNC79 GPRASP2	3.13e-05	184	145	6	3d8008f8d2e39c0d7a3cabc45620027491da03cf
ToppCell	TCGA-Pancreas-Primary_Tumor-Pancreatic_Adenocarcinoma-Ductal_Adenocarcinoma-4\|TCGA-Pancreas / Sample_Type by Project: Shred V9	DMGDH ADAMTS3 ROR1 TENM3 SOCS5 NAV3	3.13e-05	184	145	6	67164bb6bcae7322cb89b585c7aa10bce35b0ecd
ToppCell	Primary_Motor_Cortex_(M1)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_PVALB_1-Inh_L5-6_PVALB_FAM150B\|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	ARHGAP42 NTF3 ROR1 DNER GLIS3 ALPK3	3.13e-05	184	145	6	7d41784eac0935e77d6bc701f20c693adf998730
ToppCell	droplet-Lung-30m-Hematologic-lymphocytic-immature_innate_lymphoid_cell-Ly6g5b+_T\|30m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	CKB KCNC1 SLA2 LTB UNC79 GPRASP2	3.13e-05	184	145	6	eeed75984ff111c0d1750df2f978163a42f20207
ToppCell	5'-GW_trimst-2-LymphNode-Mesenchymal-fibroblastic-Stromal_3_(C7+)\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	VIM ANXA1 SERPINF1 ITGA7 NRP1 NAV3	3.13e-05	184	145	6	4d4d8f3f44c67d74c57e7af7b7c158f0157b2f49
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell_/_Pericyte\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	ARHGAP42 OPN4 NTF3 ITGA7 SPECC1 EGFLAM	3.23e-05	185	145	6	7092436b4db90289516ed130ade596e3021cffaf
ToppCell	Control-Epithelial_alveolar-AT_2-Differentiating_AT2\|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	CACNB4 ROR1 BMP3 LMO7 NAV2 PLEKHA7	3.23e-05	185	145	6	0d2add28ac1f4fa6de7699be009bf8391badaf4c
ToppCell	COVID-19-Epithelial_cells-Airway_club\|COVID-19 / group, cell type (main and fine annotations)	DPP10 GLIS3 ACSS2 LMO7 NAV2 PLEKHA7	3.23e-05	185	145	6	cfe6fd73d817e173fe803bc1683c291d9bcb8608
ToppCell	ILEUM-inflamed-(7)_Lymphatics\|inflamed / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)	ITGA2B UNC5A TIE1 SLC24A1 TNS1 DMTN	3.23e-05	185	145	6	d711dd2e91cfee723dae1ccb2b910b8cf3becc3b
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell_/_Pericyte-\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	ARHGAP42 OPN4 NTF3 ITGA7 SPECC1 EGFLAM	3.23e-05	185	145	6	a8ca7819066d5297ef6966e7f3e2c9f8a7673fdc
ToppCell	facs-Heart-RA-24m-Mesenchymal-valve_cell\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	NTF3 ITGA7 TTBK1 ADRB1 NRXN1 LOXL2	3.23e-05	185	145	6	10ddf38d908525b4258f9d2da8be4c56ebc08ff4
ToppCell	Mid-temporal_gyrus_(MTG)-Neuronal-Inh_GABAergic-i_Gaba_2-GABA_VIP_1-Inh_L1_VIP_PRSS8\|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	ARHGAP42 ROR1 MTSS1 DNER OPRK1 PLEKHA7	3.23e-05	185	145	6	4c42bd3cd72f91f4d4ebb849069a03761a2cd662
ToppCell	facs-Heart-RA-24m-Mesenchymal-valve_cell\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	NTF3 ITGA7 TTBK1 ADRB1 NRXN1 LOXL2	3.23e-05	185	145	6	c4ef8d9f8b9769e887daac4efd9dc05738b28ae2
ToppCell	Fetal_29-31_weeks-Mesenchymal-airway_smooth_muscle_cell-D088\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	ARHGAP42 GLIS3 TGFBI SNED1 NAV2 TNS1	3.23e-05	185	145	6	e58a009aaf342be019a909747b1895d5987d4daf
ToppCell	3'-GW_trimst-1-SmallIntestine-Neuronal-Glial_immature-Glia_1_(DHH+)\|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	VIM ANXA1 GRIK2 NRXN1 TENM3 EGFLAM	3.23e-05	185	145	6	dd17025d8c423aa0a451ac7f1f301c93528e0229
ToppCell	P28-Endothelial-capillary_endothelial_cell\|P28 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	VIM SIPA1 NRP1 PLLP ADRB1 TIE1	3.33e-05	186	145	6	26a625ca0300055d6af3472aa0bfba59b73db292
ToppCell	facs-Lung-Endomucin-3m-Endothelial-Capillary_Aerocyte_endothelial_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TRIB2 NRP1 PLLP LMO7 LRP4 KCNQ1	3.33e-05	186	145	6	9d6cb36aa0aae69fe584dad31deafcfdcc9fd1db
ToppCell	3'-GW_trimst-2-LargeIntestine-Mesenchymal-Pericytes-angiogenic_pericyte\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	VIM ANXA1 ITGA7 NRP1 EGFLAM OLFM2	3.33e-05	186	145	6	0b2ce9b8a4382d583240647217ad5e2d3fa555c1
ToppCell	P07-Endothelial-capillary_endothelial_cell\|P07 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	VIM SIPA1 NRP1 PLLP ADRB1 TIE1	3.33e-05	186	145	6	72aab20b848dd9e1101a4bc2466e08aed5f8bbb6
ToppCell	COPD-Epithelial-ATI\|COPD / Disease state, Lineage and Cell class	ROR1 CKB PLLP LMO7 NAV2 TNS1	3.33e-05	186	145	6	df0977f6f48a2d4e11b59971f098b01204242f0f
ToppCell	LPS-IL1RA+antiTNF-Epithelial_alveolar-AT_1-Differentiating_AT1\|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	PDE7A ROR1 PLLP LMO7 NAV2 PLEKHA7	3.33e-05	186	145	6	3aebe163799109ffc67e4e10ee47c2dd0886a92c
ToppCell	Substantia_nigra-Neuronal-Inhibitory\|Substantia_nigra / BrainAtlas - Mouse McCarroll V32	SPIRE2 OPRK1 CNNM1 MAST1 UNC79 DMTN	3.33e-05	186	145	6	9d3efe2a4feea2bc205a7e45b9b9f9ed9b3609ce
ToppCell	facs-Limb_Muscle-Muscle_forelimb_and_hindlimb-18m-Mesenchymal-mesenchymal_stem_cell\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ANXA1 SERPINF1 ITGA5 TGFBI LOXL2 CCL11	3.33e-05	186	145	6	a7ab70b049742dfe7ee30557031bfac6412edf52
ToppCell	E16.5-samps-Mesenchymal-Myofibroblast\|E16.5-samps / Age Group, Lineage, Cell class and subclass	NTF3 ESPNL CKB TGFBI LOXL2 ADAMTS14	3.33e-05	186	145	6	e044b3428b7eacfdc72d0f57cdabaa1de04c74cd
ToppCell	3'-Adult-LargeIntestine-Mesenchymal-Pericytes-Pericyte\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	TRIB2 NTF3 ITGA7 EGFLAM OLFM2 TNS1	3.43e-05	187	145	6	150023e6a50c9da461f2321074d2d5e96caafb06
ToppCell	E17.5-Endothelial-unknown_endothelial_cell\|E17.5 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	VIM TRIB2 SIPA1 NRP1 PLLP TIE1	3.43e-05	187	145	6	da885c26ccc5189b1ff1f607552e00a5c0e49e7e
Computational	Genes in the cancer module 27.	TRIB2 HTR3A ROR1 GRIK2 ITGA2B ITGA5 OPRK1 NRP1 ADRB1 CSF2RB TIE1 CXCR2	4.21e-05	355	91	12	MODULE_27
Disease	blood cobalt measurement	DNER MUC16 OPRK1 KCNQ1 ADAMTS14 TNS1	9.34e-06	101	141	6	EFO_0007577
Disease	intellectual developmental disorder with ocular anomalies and distinctive facial features (implicated_via_orthology)	MTSS1 MTSS2	2.27e-05	2	141	2	DOID:0081301 (implicated_via_orthology)
Disease	cataract (biomarker_via_orthology)	ANXA1 CRYAA CCL11	2.95e-05	13	141	3	DOID:83 (biomarker_via_orthology)
Disease	mean arterial pressure, alcohol drinking	ARHGAP42 HECTD4 SIPA1 ADRB1 PLEKHA7	1.10e-04	98	141	5	EFO_0004329, EFO_0006340
Disease	diastolic blood pressure, alcohol consumption measurement	ARHGAP42 HECTD4 SIPA1 ADRB1	1.31e-04	54	141	4	EFO_0006336, EFO_0007878
Disease	Metastatic melanoma	ROR1 TTBK1 ALPK3 MAST1	1.31e-04	54	141	4	C0278883
Disease	reticulocyte count	ARHGAP42 SPIRE2 HECTD4 SIPA1 SPECC1 NRP1 ADRB1 DCAF10 PKD1 PKLR MAST1 DEPDC5 HERC1 PLEKHA7 TNS1	1.50e-04	1045	141	15	EFO_0007986
Disease	Pseudoaphakia	VIM GALK1 CRYAA	2.01e-04	24	141	3	C0524524
Disease	Lens Opacities	VIM GALK1 CRYAA	2.01e-04	24	141	3	C1510497
Disease	Polycystic Kidney - body part	GLIS3 PKD1	2.25e-04	5	141	2	C1567435
Disease	diastolic blood pressure, alcohol drinking	ARHGAP42 HECTD4 SIPA1 ADRB1 PLEKHA7	2.63e-04	118	141	5	EFO_0004329, EFO_0006336
Disease	ferritin measurement	TRIB2 IARS2 TENM3 SLC24A1 ELL	2.74e-04	119	141	5	EFO_0004459
Disease	cortical thickness	SPIRE2 ADAMTS3 ROR1 ESPNL GLIS3 SPECC1 NRP1 PKD1 NAV3 NAV2 LRP4 DLEC1 PLEKHA7 TNS1 ELL	2.94e-04	1113	141	15	EFO_0004840
Disease	systolic blood pressure, alcohol drinking	ARHGAP42 HECTD4 SIPA1 ADRB1 PLEKHA7	3.83e-04	128	141	5	EFO_0004329, EFO_0006335
Disease	pentachlorophenol measurement	DNER MUC16 OPRK1 TNS1	4.21e-04	73	141	4	EFO_0022071
Disease	parathion measurement	DNER MUC16 OPRK1 TNS1	4.21e-04	73	141	4	EFO_0022070
Disease	potassium chromate measurement	DNER MUC16 OPRK1 TNS1	4.21e-04	73	141	4	EFO_0022072
Disease	mercuric chloride measurement	DNER MUC16 OPRK1 TNS1	4.21e-04	73	141	4	EFO_0022068
Disease	heptachlor epoxide measurement	DNER MUC16 OPRK1 TNS1	4.21e-04	73	141	4	EFO_0022067
Disease	methoxychlor measurement	DNER MUC16 OPRK1 TNS1	4.21e-04	73	141	4	EFO_0022069
Disease	4,6-dinitro-o-cresol measurement	DNER MUC16 OPRK1 TNS1	4.21e-04	73	141	4	EFO_0022053
Disease	2,4,5-trichlorophenol measurement	DNER MUC16 OPRK1 TNS1	4.21e-04	73	141	4	EFO_0022052
Disease	azinphos methyl measurement	DNER MUC16 OPRK1 TNS1	4.21e-04	73	141	4	EFO_0022055
Disease	aldrin measurement	DNER MUC16 OPRK1 TNS1	4.21e-04	73	141	4	EFO_0022054
Disease	dicofol measurement	DNER MUC16 OPRK1 TNS1	4.21e-04	73	141	4	EFO_0022060
Disease	disulfoton measurement	DNER MUC16 OPRK1 TNS1	4.21e-04	73	141	4	EFO_0022062
Disease	dieldrin measurement	DNER MUC16 OPRK1 TNS1	4.21e-04	73	141	4	EFO_0022061
Disease	endrin measurement	DNER MUC16 OPRK1 TNS1	4.21e-04	73	141	4	EFO_0022064
Disease	endosulfan measurement	DNER MUC16 OPRK1 TNS1	4.21e-04	73	141	4	EFO_0022063
Disease	heptachlor measurement	DNER MUC16 OPRK1 TNS1	4.21e-04	73	141	4	EFO_0022066
Disease	ethion measurement	DNER MUC16 OPRK1 TNS1	4.21e-04	73	141	4	EFO_0022065
Disease	chlorpyrifos measurement	DNER MUC16 OPRK1 TNS1	4.21e-04	73	141	4	EFO_0022057
Disease	cadmium chloride measurement	DNER MUC16 OPRK1 TNS1	4.21e-04	73	141	4	EFO_0022056
Disease	diazinon measurement	DNER MUC16 OPRK1 TNS1	4.21e-04	73	141	4	EFO_0022059
Disease	dibutyl phthalate measurement	DNER MUC16 OPRK1 TNS1	4.21e-04	73	141	4	EFO_0022058
Disease	environmental exposure measurement	DNER MUC16 OPRK1 TNS1	4.21e-04	73	141	4	EFO_0008360
Disease	DDT metabolite measurement	DNER MUC16 OPRK1 TNS1	4.44e-04	74	141	4	EFO_0007886
Disease	intellectual disability (implicated_via_orthology)	RBL2 ITGA2B ITGA5 GPRASP2	4.67e-04	75	141	4	DOID:1059 (implicated_via_orthology)
Disease	HWESASXX measurement	CACNB4 DPP10	4.69e-04	7	141	2	EFO_0021147
Disease	Angle Closure Glaucoma	GLIS3 PLEKHA7	4.69e-04	7	141	2	C0017605
Disease	Acute Coronary Syndrome	VIM CKB CKM	5.25e-04	33	141	3	C0948089
Disease	coronary artery disease	ARHGAP42 ANKRD31 DPP10 ADAMTS3 HECTD4 SIPA1 NRP1 CKB NRXN1 PAN2 DLEC1 PLEKHA7 TNS1 ELL PARP12	6.11e-04	1194	141	15	EFO_0001645
Disease	Juvenile Myoclonic Epilepsy	CACNB4 CILK1	6.23e-04	8	141	2	C0270853
Disease	neuroimaging measurement	KIF21B SPIRE2 ADAMTS3 ROR1 GLIS3 GTDC1 NRP1 YOD1 PKD1 NAV3 NAV2 PLEKHA7 TNS1 DMTN	6.24e-04	1069	141	14	EFO_0004346
Disease	Cataract	VIM GALK1 CRYAA	7.37e-04	37	141	3	C0086543
Disease	Uveitis	SERPINF1 CRYAA	7.98e-04	9	141	2	C0042164
Disease	dry eye syndrome (is_marker_for)	ANXA1 MUC16	9.95e-04	10	141	2	DOID:10140 (is_marker_for)
Disease	cerebral infarction (biomarker_via_orthology)	VIM ANXA1	9.95e-04	10	141	2	DOID:3526 (biomarker_via_orthology)
Disease	primary angle closure glaucoma	GLIS3 PLEKHA7	1.21e-03	11	141	2	EFO_1001506
Disease	chronic obstructive pulmonary disease (is_marker_for)	NTF3 CCL11 NOS1 CXCR2	1.23e-03	97	141	4	DOID:3083 (is_marker_for)
Disease	Mood Disorders	HTR3A NTF3 GRIK2 OPRK1 ADRB1	1.31e-03	168	141	5	C0525045
Disease	retinopathy of prematurity (biomarker_via_orthology)	SERPINF1 NOS1	1.45e-03	12	141	2	DOID:13025 (biomarker_via_orthology)
Disease	neuroticism measurement, cognitive function measurement	RBL2 GLIS3 NRP1 CKB TTBK1 TENM3 NAV2 METTL15 NOS1	1.65e-03	566	141	9	EFO_0007660, EFO_0008354
Disease	reticulocyte measurement	ARHGAP42 SPIRE2 HECTD4 SIPA1 SPECC1 ADRB1 PKLR MAST1 KCNQ1 DEPDC5 PLEKHA7 TNS1 ELL	1.66e-03	1053	141	13	EFO_0010700
Disease	pleurisy (implicated_via_orthology)	ANXA1 CCL11	1.71e-03	13	141	2	DOID:10247 (implicated_via_orthology)
Disease	very low density lipoprotein cholesterol measurement, cholesteryl esters:total lipids ratio	ANKRD31 DMGDH HECTD4 SIPA1 ADRB1 LRP4	1.74e-03	264	141	6	EFO_0008317, EFO_0020944
Disease	colonic neoplasm, overall survival	DPP10 DSG3	1.99e-03	14	141	2	EFO_0000638, EFO_0004288
Disease	mean arterial pressure, alcohol consumption measurement	ARHGAP42 SIPA1 ADRB1	1.99e-03	52	141	3	EFO_0006340, EFO_0007878
Disease	endometriosis (biomarker_via_orthology)	SERPINF1 CCL11	2.60e-03	16	141	2	DOID:289 (biomarker_via_orthology)
Disease	blood nickel measurement	DNER MUC16 OPRK1 TNS1	2.67e-03	120	141	4	EFO_0007583
Disease	body fat distribution	ADAMTS3 UBE4A SOCS5 PKLR ADAMTS14	2.92e-03	202	141	5	EFO_0004341
Disease	creatinine measurement	NPHS1 KIF21B DMGDH SPIRE2 PDE7A DNAJC16 GLIS3 ANKRD11 KCNQ1 DLEC1 PLEKHA7 ELL	3.02e-03	995	141	12	EFO_0004518
Disease	intraocular pressure measurement	TRIB2 GLIS3 LMO7 LRP4 DLEC1 PLEKHA7 METTL15 TNS1	3.19e-03	509	141	8	EFO_0004695
Disease	cystic fibrosis (is_marker_for)	ADRB1 CCL11 NOS1	3.29e-03	62	141	3	DOID:1485 (is_marker_for)
Disease	Schizophrenia	SHANK1 HTR3A ADAMTS3 NTF3 AMBRA1 GRIK2 CKB PLLP CSF2RB NRXN1 NOS1	3.51e-03	883	141	11	C0036341
Disease	type 1 diabetes mellitus (biomarker_via_orthology)	ADRB1 CCL11	3.68e-03	19	141	2	DOID:9744 (biomarker_via_orthology)
Disease	colorectal cancer, inflammatory bowel disease	GRIK2 BMP3	3.68e-03	19	141	2	EFO_0003767, MONDO_0005575
Disease	susceptibility to cold sores measurement	NUGGC MUC16 DCAF10	3.76e-03	65	141	3	EFO_0008402
Disease	smoking status measurement	DPP10 PDE7A MTERF1 HECTD4 CILK1 GRIK2 NRXN1 NAV2 DLEC1 HERC1 METTL15 UNC79 ELL	3.81e-03	1160	141	13	EFO_0006527
Disease	serum homoarginine measurement	KCNQ1 TNS1	4.07e-03	20	141	2	EFO_0005421
Disease	hyperglycemia (biomarker_via_orthology)	ADRB1 PKLR	4.49e-03	21	141	2	DOID:4195 (biomarker_via_orthology)
Disease	activities of daily living score measurement	GRIK2 NOS1	4.49e-03	21	141	2	EFO_0008451

Protein segments in the cluster

Peptide	Gene	Start	Entry
SRASQRSVRLAPVYQ	TGFBI	661	Q15582
TSPFRYQSLLTRARA	ADRB1	161	P08588
RYSTVQAARTPGSLE	BMP3	66	P12645
TLTIPQFRESLRSYA	EGFLAM	606	Q63HQ2
YRARQDSVSLRPSIR	ELL	41	P55199
LSRRARSTLGQYSPL	CFAP97	476	Q9P2B7
RSTLGQYSPLRASRT	CFAP97	481	Q9P2B7
RPLSTNLYRSVSVDI	ANKRD11	1781	Q6UB99
RQTPSPRLALSTRYS	GSE1	836	Q14687
SRNTTRPALLRLSDY	HTR3A	26	P46098
YLLSVRPETSLSSNR	ALPK3	241	Q96L96
YSSVRPASRGVTQRL	SPECC1	871	Q5M775
SPTRETLTYAQAQRI	BRPF3	26	Q9ULD4
RSRSLFTAYATRPVL	CCDC144CP	1126	Q8IYA2
SRSAHVPSLQRYREL	ACSS2	36	Q9NR19
QPSTERPRTSAYIRL	AMBRA1	276	Q9C0C7
ILRQGSADSYTSRPS	CACNB4	46	O00305
SSLTGRVIEQRIPYR	DAXX	246	Q9UER7
LSTESSPRGRQLYSA	DPP10	441	Q8N608
YRQSLSLIERGNPSR	ADAMTS14	316	Q8WXS8
YHFRSRSVLVQRSLP	OLFM2	291	O95897
VDLTSLRGTRPYNQR	PLLP	126	Q9Y342
RGASSYVRETLPVLT	YOD1	136	Q5VVQ6
SRTVNGSRLVPYSCR	LEMD3	241	Q9Y2U8
LGRSITSPTTLYDRY	RBL2	656	Q08999
FNTILTTRSYPQLRR	ANXA1	221	P04083
LAVSPSRRINRLVTY	ANKRD31	751	Q8N7Z5
SSSPLYSRGLVSRNR	DEPDC5	831	O75140
SPSVVVSARTLNNRY	DSG3	506	P32926
TSAYQVPSLSTRLTR	MUC16	10411	Q8WXI7
TTFTLTGLQPSTRYR	NPHS1	996	O60500
RFIPTYTSRLAIISQ	PAN2	291	Q504Q3
RRTRSGASPLYLACQ	ESPNL	166	Q6ZVH7
VSIYSTRRPVLARTH	KCNQ1	91	P51787
STYQHLRRPRGLSSL	SLC24A1	36	O60721
LDPNYVLSSRVRTGR	CKB	121	P12277
SSYPTTTVLPTRRAQ	HERC1	2686	Q15751
QTDPTTGYRRLLRFS	LOXL2	586	Q9Y4K0
RYRSLAQPATTTARL	MTSS2	306	Q765P7
STIPRNSDISQSYRR	MTSS1	546	O43312
PRQLSQRRGAISYDS	PDE7A	41	Q13946
YTTPLRRAAVSRLGN	NAV3	781	Q8IVL0
LLFRRTVYSSNVSPA	CXCR2	181	P25025
VGSYPILRARRTTSS	DCAF10	336	Q5QP82
SLRRSLSRASARSPY	KIF21B	501	O75037
NVRHSLASSEYPVRR	GALK1	226	P51570
LTDVTYTSNLVRLRP	DNAJC16	606	Q9Y2G8
RSSTRRNSYINTPVA	DEPDC1	516	Q5TB30
RVSASLPRSYRKTDT	LMO7	891	Q8WWI1
SYRIITDFPSLTRNL	MANSC1	116	Q9H8J5
TTGRSAQLLSRYRPR	PKLR	476	P30613
RYVSAQPLAGRQSRT	TUBGCP2	231	Q9BSJ2
IITERRYLSSVPSNF	NRXN1	851	Q9ULB1
PLRYTSILTTVRVAQ	OR51A2	131	Q8NGJ7
PLRYTSILTTVRVAQ	OR51A4	131	Q8NGJ6
RLSRYRASPSATLAA	HECTD4	86	Q9Y4D8
ASAIVQARSIYPITR	METTL15	236	A6NJ78
QRRYNSPRVLLSDST	NTF3	96	P20783
NTSIRIGPARRSSYK	MAST1	1056	Q9Y2H9
GVTLRTYEVTNRLRS	NOS1	1401	P29475
SSDLVSRLPTIYRNA	PARP12	216	Q9H0J9
QPASYQRRLLVTRSG	PPIG	316	Q13427
FQRRAARLPVSSTYS	FAM171A2	156	A8MVW0
ALSTRFIRIYPERAT	NRP1	556	O14786
VIYTFCRSRSLRTPA	OPN4	91	Q9UHM6
VYRGRPIVSASASLT	ITGA5	486	P08648
SATYRIRRTEPLQTN	ADAMTS3	131	O15072
STYVARVRTRLAPGS	CSF2RB	206	P32927
GTRHQTYRSTLRTLP	KCNC1	16	P48547
TYRSTLRTLPGTRLA	KCNC1	21	P48547
RLGRYSFSSPLTRLS	FRMPD2	1291	Q68DX3
RTSPTSLVAYINGSR	GLIS3	166	Q8NEA6
KRRASATINRITPSY	DTHD1	406	Q6ZMT9
RPTQRVSGLYQRLES	DMGDH	466	Q9UI17
TRSLNSENSYVSPRI	MARCHF7	306	Q9H992
RAIVVTLSYSLQTPR	ITGA7	631	Q13683
TLSYSLQTPRLRRQA	ITGA7	636	Q13683
ALRSHDRSTRPLYIS	ENDOV	196	Q8N8Q3
RRVPRLIYTSTVNVA	SDR42E2	136	A6NKP2
SQPYSARSRLSAIEI	CLDN12	221	P56749
RRYRLPSNVDQSALS	CRYAA	116	P02489
RLYRRTNKEVPTTAS	COG2	591	Q14746
RSRSLFTAYATRPVL	CCDC144A	1316	A2RUR9
RNRTLLPNTTLTYDT	GRIK2	66	Q13002
RARTSALYFSQTIPI	GTDC1	41	Q4AE62
LQNTTTTSRYLRVLP	DLEC1	396	Q9Y238
ICRISRIEYQGSSRP	DNER	661	Q8NFT8
PAYGRTTLSRLQSTE	DMTN	291	Q08495
RSRAVFLELTRYSPA	PKD1	3846	P98161
RLSRTPGNRIVYLYT	RPL34	21	P49207
SNRLGPTSRLRYSRF	MOXD2P	21	A6NHM9
STSRVRNTVQDPAYL	OPRK1	356	P41145
LSERSFSRGYPIRQS	MINAR1	141	Q9UPX6
PLQEGVRTARTSYRC	NUGGC	516	Q68CJ6
TLSPVNTTYQLRVSR	SIDT2	136	Q8NBJ9
QLSRVYPSGLRTDSS	PLCD4	546	Q9BRC7
RRGSYSLSVRLSRPA	SLA2	126	Q9H6Q3
CVTPGTRLARRDSYS	SOCS5	101	O75159
LDPNYVLSSRVRTGR	CKM	121	P06732
RLRLDTASSNGYQRP	ARHGAP42	781	A6NI28
LRPRSSYSLTQDRTV	OR5AU1	311	Q8NGC0
LLNYPSSRVRTSFLE	GPRASP2	646	Q96D09
YSRIVLSVSRPQTRK	GNRHR2	136	Q96P88
YSAPLRRQLASRGSS	NAV2	846	Q8IVL1
LQQSSTIAPYVTLRR	PLEKHA7	1026	Q6IQ23
RNYLAASIRPVSEVT	MRRF	16	Q96E11
RPRRSFSELYTLSLQ	SIPA1	766	Q96FS4
RALEGLVYRSPTATR	TELO2	536	Q9Y4R8
NSGRYRDTVLLPQTS	IARS2	56	Q9NSE4
GYPRASIARTLRTIV	SLC25A42	261	Q86VD7
AQILPGSRGSYRTRS	TBC1D26	226	Q86UD7
RAEYSPCRGNTLSRI	ITGA2B	171	P08514
RGYSLSAPSRIRVCQ	SNED1	726	Q8TER0
YVPERTSSLQRQRLS	SHANK1	1911	Q9Y566
IPLQRLESYRRITSG	CCL11	41	P51671
TSYQRRDTPTLRSAA	CILK1	471	Q9UPZ9
YAANSPRRILRNIGT	CLHC1	316	Q8NHS4
AGSSPRLDYSRIIQS	NCAPD3	726	P42695
ATVSEILRSGYTRIP	CNNM1	451	Q9NRU3
EPRRLSFRSTIYGSR	ROR1	101	Q01973
NSPATQEYRTLSGRI	TMPRSS11D	66	O60235
SLTYRVPERLRQGSC	TSPY2	6	A6NKD2
YRRVNSPESERLSTA	TTBK1	451	Q5TCY1
YRVRSSTSPTTNVLL	SERPINF1	66	P36955
TSTIIRGLNASTRYL	TIE1	701	P35590
NTTPRRSRQTQSLYI	SPIRE2	691	Q8WWL2
RSRQTQSLYIPNTRT	SPIRE2	696	Q8WWL2
STPITIARYGRSRNK	TRIB2	6	Q92519
ASTIGFYSVSRLPTR	RNF175	206	Q8N4F7
DRRPTLSRQSSASGY	TNS1	1331	Q9HBL0
RTYSLGSALRPSTSR	VIM	36	P08670
YATRSSAVRLRSSVP	VIM	61	P08670
IASIISRYPRAITRT	MTERF1	121	Q99551
SDTNTRRIYRPKSLT	TENM3	1231	Q9P273
GRPSSYRALRSAVSS	TESK1	36	Q15569
YGVTSSTARRILQSL	NUP153	301	P49790
LSTQNYFRSLPRGTS	UNC5A	426	Q6ZN44
RTTLTRERNASVYSP	TOPORS	181	Q9NS56
PRNLNSSVRGDRVYS	TOPORS	571	Q9NS56
ISDSRLYDSSPSRQR	ZC3H12C	751	Q9C0D7
GRSYSPTLFAQTVRV	UBE4A	936	Q14139
LSPERHVRTRLYFTS	PPIP5K2	811	O43314
VLSTYRLQSRSRPSA	TOGARAM1	16	Q9Y4F4
SSLRTSDSYRIDPRN	USP2	151	O75604
SYQVSPALRSETARR	WDR87	911	Q6ZQQ6
YIDPSNLRRSGTIST	UBR5	1746	O95071
QELPSYRSIARRRTT	TMC7	41	Q7Z402
NPTVTRSLLYSVLRD	UNC79	91	Q9P2D8
DPQGRSVTLRSSLYR	LTB	151	Q06643
TYRSTLRTLPGTRLA	KCNC3	101	Q14003
SPETYLLFSSRGSIR	LRP4	1351	O75096
TYRQTTSPSGSLLRS	NFKB2	806	Q00653