Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
HumanPhenoAccessory carpal bones

FLNA FLNB

1.62e-052212HP:0004232
HumanPhenoBipartite calcaneus

FLNA FLNB

1.62e-052212HP:0008127
DomainRCC1

SERGEF RPGR HERC5

5.26e-0520693PF00415
DomainRCC1_1

SERGEF RPGR HERC5

6.12e-0521693PS00625
DomainRCC1_2

SERGEF RPGR HERC5

6.12e-0521693PS00626
DomainRCC1_3

SERGEF RPGR HERC5

6.12e-0521693PS50012
DomainReg_chr_condens

SERGEF RPGR HERC5

7.07e-0522693IPR000408
Domain-

SERGEF RPGR HERC5

7.07e-05226932.130.10.30
DomainRCC1/BLIP-II

SERGEF RPGR HERC5

8.11e-0523693IPR009091
DomainIntegrin_bsu_cyt_dom

ITGB1 ITGB2

2.00e-046692IPR014836
DomainIntegrin_b_cyt

ITGB1 ITGB2

2.00e-046692SM01241
DomainIntegrin_b_cyt

ITGB1 ITGB2

2.00e-046692PF08725
DomainIntegrin_bsu_tail

ITGB1 ITGB2

2.79e-047692IPR012896
DomainIntegrin_B_tail

ITGB1 ITGB2

2.79e-047692SM01242
DomainIntegrin_B_tail

ITGB1 ITGB2

2.79e-047692PF07965
DomainIntegrin_beta

ITGB1 ITGB2

3.71e-048692PF00362
DomainINB

ITGB1 ITGB2

3.71e-048692SM00187
DomainIntegrin_bsu_VWA

ITGB1 ITGB2

3.71e-048692IPR002369
DomainIntegrin_bsu

ITGB1 ITGB2

4.76e-049692IPR015812
DomainIntegin_beta_N

ITGB1 ITGB2

4.76e-049692IPR033760
DomainINTEGRIN_BETA

ITGB1 ITGB2

4.76e-049692PS00243
DomainPSI_integrin

ITGB1 ITGB2

4.76e-049692PF17205
DomainIG_FLMN

FLNA FLNB

5.94e-0410692SM00557
DomainFilamin

FLNA FLNB

7.24e-0411692PF00630
DomainFILAMIN_REPEAT

FLNA FLNB

7.24e-0411692PS50194
DomainFilamin/ABP280_rpt

FLNA FLNB

7.24e-0411692IPR001298
DomainFilamin/ABP280_repeat-like

FLNA FLNB

7.24e-0411692IPR017868
DomainEGF_extracell

HHIP ITGB1 ITGB2

1.42e-0360693IPR013111
DomainEGF_2

HHIP ITGB1 ITGB2

1.42e-0360693PF07974
DomainActinin_actin-bd_CS

FLNA FLNB

3.24e-0323692IPR001589
DomainACTININ_2

FLNA FLNB

3.24e-0323692PS00020
DomainACTININ_1

FLNA FLNB

3.24e-0323692PS00019
DomainIntegrin_dom

ITGB1 ITGB2

3.82e-0325692IPR032695
DomainHECT

NEDD4L HERC5

4.45e-0327692PF00632
DomainHECTc

NEDD4L HERC5

4.45e-0327692SM00119
DomainHECT_dom

NEDD4L HERC5

4.45e-0327692IPR000569
DomainHECT

NEDD4L HERC5

4.45e-0327692PS50237
Pubmed

The small GTPase Rap1 is required for Mn(2+)- and antibody-induced LFA-1- and VLA-4-mediated cell adhesion.

RAP1GAP ITGB1 ITGB2

7.45e-08569312171996
Pubmed

The ADAP/SKAP55 signaling module regulates T-cell receptor-mediated integrin activation through plasma membrane targeting of Rap1.

RAP1GAP ITGB1 ITGB2

1.49e-07669316980616
Pubmed

Genome-wide CRISPR screen identifies HNRNPL as a prostate cancer dependency regulating RNA splicing.

LUC7L FLNB PPP2R2A NEDD4L ARHGAP10 STXBP5L UCKL1 ACP3 FRMPD1 PON2 CHD1L STK32C ITGB1 CNOT1 SLC35F5

1.78e-071489691528611215
Pubmed

The Z-disc proteins myotilin and FATZ-1 interact with each other and are connected to the sarcolemma via muscle-specific filamins.

FLNA FLNB ITGB1

2.60e-07769316076904
Pubmed

MYH9-dependent polarization of ATG9B promotes colorectal cancer metastasis by accelerating focal adhesion assembly.

FLNA FLNB ITGB1

4.16e-07869334131310
Pubmed

Different splice variants of filamin-B affect myogenesis, subcellular distribution, and determine binding to integrin [beta] subunits.

FLNA FLNB ITGB1

6.22e-07969311807098
Pubmed

A protein-interaction network of interferon-stimulated genes extends the innate immune system landscape.

USP34 LUC7L FLNA FLNB PPP2R2A CEBPD PON2 SDF4 SLC39A14 SUCLG2 ITGB1 CNOT1 HERC5 VDAC3

7.47e-071440691430833792
Pubmed

ABCE1 is a highly conserved RNA silencing suppressor.

FLNA FLNB PPP2R2A SDF4 SUCLG2 VDAC3

3.33e-0620469625659154
Pubmed

Filamin A regulates cell spreading and survival via beta1 integrins.

FLNA ITGB1

3.88e-06269218177638
Pubmed

The role of the specificity-determining loop of the integrin beta subunit I-like domain in autonomous expression, association with the alpha subunit, and ligand binding.

ITGB1 ITGB2

3.88e-06269211914080
Pubmed

Filamin binds to the cytoplasmic domain of the beta1-integrin. Identification of amino acids responsible for this interaction.

FLNA ITGB1

3.88e-0626929722563
Pubmed

Disruption of the Flnb gene in mice phenocopies the human disease spondylocarpotarsal synostosis syndrome.

FLNA FLNB

3.88e-06269217635842
Pubmed

Structural and functional aspects of filamins.

FLNA FLNB

3.88e-06269211336782
Pubmed

The variants at FLNA and FLNB contribute to the susceptibility of hypertension and stroke with differentially expressed mRNA.

FLNA FLNB

3.88e-06269233649519
Pubmed

Dissecting Integrin Expression and Function on Memory B Cells in Mice and Humans in Autoimmunity.

ITGB1 ITGB2

3.88e-06269230949178
Pubmed

Effect of medium change on the development of in vitro matured and fertilized bovine oocytes cultured in medium containing amino acids.

FLNB ITGB1

3.88e-06269210676904
Pubmed

Platelet binding to monocytes increases the adhesive properties of monocytes by up-regulating the expression and functionality of beta1 and beta2 integrins.

ITGB1 ITGB2

3.88e-06269216415171
Pubmed

beta1 and beta2 integrins activate different signalling pathways in monocytes.

ITGB1 ITGB2

3.88e-06269211931654
Pubmed

Decreased stroma adhesion capacity of CD34+ progenitor cells from mobilized peripheral blood is not lineage- or stage-specific and is associated with low beta 1 and beta 2 integrin expression.

ITGB1 ITGB2

3.88e-06269212183834
Pubmed

Somatostatin down-regulates LFA-1 activation by modulating Rap1 expression in CD4+ and CD8+ T cells.

RAP1GAP ITGB2

3.88e-06269215544853
Pubmed

Filamin depletion blocks endoplasmic spreading and destabilizes force-bearing adhesions.

FLNA FLNB

3.88e-06269221325628
Pubmed

Filamin A-beta1 integrin complex tunes epithelial cell response to matrix tension.

FLNA ITGB1

3.88e-06269219458194
Pubmed

KCTD13-mediated ubiquitination and degradation of GluN1 regulates excitatory synaptic transmission and seizure susceptibility.

DENND2A FLNA FLNB PPP2R2A IL16 RAP1GAP NEDD4L LRIG1 NAPB LZTS1 RPS23 CNOT1 VDAC3

4.14e-061431691337142655
Pubmed

AMPK, a Regulator of Metabolism and Autophagy, Is Activated by Lysosomal Damage via a Novel Galectin-Directed Ubiquitin Signal Transduction System.

FLNA FLNB PITRM1 RPS23 SLC39A14 ITGB1 CNOT1 VDAC3

5.28e-0648469831995728
Pubmed

Filamins as integrators of cell mechanics and signalling.

FLNA FLNB

1.16e-05369211252955
Pubmed

Aryl Hydrocarbon Receptor Defect Attenuates Mitogen-Activated Signaling through Leucine-Rich Repeats and Immunoglobulin-like Domains 1 (LRIG1)-Dependent EGFR Degradation.

LRIG1 AHR

1.16e-05369234576152
Pubmed

Urokinase-type plasminogen activator binding to its receptor stimulates tumor cell migration by enhancing integrin-mediated signal transduction.

ITGB1 ITGB2

1.16e-05369210388537
Pubmed

Opposing FlnA and FlnB interactions regulate RhoA activation in guiding dynamic actin stress fiber formation and cell spreading.

FLNA FLNB

1.16e-05369228175289
Pubmed

Activation of Epac stimulates integrin-dependent homing of progenitor cells.

ITGB1 ITGB2

1.16e-05369218032709
Pubmed

Structure of three tandem filamin domains reveals auto-inhibition of ligand binding.

FLNA ITGB1

1.16e-05369217690686
Pubmed

Increased Expressions of Integrin Subunit β1, β2 and β3 in Patients with Acute Infection.

ITGB1 ITGB2

1.16e-05369226283883
Pubmed

GPIbα regulates platelet size by controlling the subcellular localization of filamin.

FLNA FLNB

1.16e-05369222174152
Pubmed

JAK2-V617F promotes venous thrombosis through β1/β2 integrin activation.

ITGB1 ITGB2

1.16e-05369230024857
Pubmed

Pro-prion binds filamin A, facilitating its interaction with integrin beta1, and contributes to melanomagenesis.

FLNA ITGB1

1.16e-05369220650901
Pubmed

Characterization of L-plastin interaction with beta integrin and its regulation by micro-calpain.

ITGB1 ITGB2

1.16e-05369220183869
Pubmed

Interaction of filamin A with the integrin beta 7 cytoplasmic domain: role of alternative splicing and phosphorylation.

FLNA ITGB1

1.16e-05369215225631
Pubmed

Filamin A and Filamin B are co-expressed within neurons during periods of neuronal migration and can physically interact.

FLNA FLNB

1.16e-05369212393796
Pubmed

alpha subunit partners to beta1 and beta2 integrins during IL-4-induced foreign body giant cell formation.

ITGB1 ITGB2

1.16e-05369217311314
Pubmed

Genomic structure and fine mapping of the two human filamin gene paralogues FLNB and FLNC and comparative analysis of the filamin gene family.

FLNA FLNB

1.16e-05369211153914
Pubmed

Sustained generation of neurons destined for neocortex with oxidative metabolic upregulation upon filamin abrogation.

FLNA FLNB

1.16e-05369238989458
Pubmed

Rap1 GTPase is required for mouse lens epithelial maintenance and morphogenesis.

RAP1GAP MIP ITGB1

1.88e-052669326212757
Pubmed

A Human Tyrosine Phosphatase Interactome Mapped by Proteomic Profiling.

USP34 FLNA FLNB PPP2R2A PITRM1 ARHGAP10 ACP3 PON2 APOD ITGB1

2.16e-05974691028675297
Pubmed

Regulated expression of p150,95 (CD11c/CD18; alpha X/beta 2) and VLA-4 (CD49d/CD29; alpha 4/beta 1) integrins during myeloid cell differentiation.

ITGB1 ITGB2

2.32e-0546928020569
Pubmed

Regulation of cell adhesion to collagen via beta1 integrins is dependent on interactions of filamin A with vimentin and protein kinase C epsilon.

FLNA ITGB1

2.32e-05469220171211
Pubmed

The SH2-containing inositol polyphosphate 5-phosphatase, SHIP-2, binds filamin and regulates submembraneous actin.

FLNA FLNB

2.32e-05469211739414
Pubmed

Interaction of presenilins with the filamin family of actin-binding proteins.

FLNA FLNB

2.32e-0546929437013
Pubmed

Structural interaction and functional regulation of polycystin-2 by filamin.

FLNA FLNB

2.32e-05469222802962
Pubmed

CD44-mediated phagocytosis induces inside-out activation of complement receptor-3 in murine macrophages.

RAP1GAP ITGB2

2.32e-05469217827392
Pubmed

Kindlin-3-mediated signaling from multiple integrin classes is required for osteoclast-mediated bone resorption.

ITGB1 ITGB2

2.32e-05469221357746
Pubmed

Klf5 controls bone marrow homing of stem cells and progenitors through Rab5-mediated β1/β2-integrin trafficking.

ITGB1 ITGB2

2.32e-05469223552075
Pubmed

Androgen-induced cell migration: role of androgen receptor/filamin A association.

FLNA ITGB1

2.32e-05469221359179
Pubmed

Epidermal growth factor (EGF) regulates α5β1 integrin activation state in human cancer cell lines through the p90RSK-dependent phosphorylation of filamin A.

FLNA ITGB1

2.32e-05469223007402
Pubmed

β1- and αv-class integrins cooperate to regulate myosin II during rigidity sensing of fibronectin-based microenvironments.

ITGB1 ITGB2

2.32e-05469223708002
Pubmed

Specific phosphorylations transmit signals from leukocyte β2 to β1 integrins and regulate adhesion.

ITGB1 ITGB2

2.32e-05469225278023
Pubmed

Chemokine stimulation of lymphocyte alpha 4 integrin avidity but not of leukocyte function-associated antigen-1 avidity to endothelial ligands under shear flow requires cholesterol membrane rafts.

ITGB1 ITGB2

2.32e-05469212163503
Pubmed

Tetraspanins CD9 and CD81 function to prevent the fusion of mononuclear phagocytes.

ITGB1 ITGB2

2.32e-05469212796480
Pubmed

Adhesion molecules involved in macrophage responses to Wallerian degeneration in the murine peripheral nervous system.

ITGB1 ITGB2

3.86e-0556929421166
Pubmed

RGS10 restricts upregulation by chemokines of T cell adhesion mediated by α4β1 and αLβ2 integrins.

ITGB1 ITGB2

3.86e-05569221705617
Pubmed

Integrin alpha2beta1 mediates the anti-angiogenic and anti-tumor activities of angiocidin, a novel tumor-associated protein.

ITGB1 ITGB2

3.86e-05569216762342
Pubmed

Characterization of plasminogen as an adhesive ligand for integrins alphaMbeta2 (Mac-1) and alpha5beta1 (VLA-5).

ITGB1 ITGB2

3.86e-05569215090462
Pubmed

CD47 plays a critical role in T-cell recruitment by regulation of LFA-1 and VLA-4 integrin adhesive functions.

ITGB1 ITGB2

3.86e-05569224006483
Pubmed

Rack1, a receptor for activated protein kinase C, interacts with integrin beta subunit.

ITGB1 ITGB2

3.86e-0556929442085
Pubmed

HIV infection of T cells: actin-in and actin-out.

FLNA FLNB

3.86e-05569219366992
Pubmed

Identification and characterization of multiple similar ligand-binding repeats in filamin: implication on filamin-mediated receptor clustering and cross-talk.

FLNA ITGB2

3.86e-05569219828450
Pubmed

Nephrocystin-conserved domains involved in targeting to epithelial cell-cell junctions, interaction with filamins, and establishing cell polarity.

FLNA FLNB

3.86e-05569212006559
Pubmed

The X-linked intellectual disability protein TSPAN7 regulates excitatory synapse development and AMPAR trafficking.

GRIA3 ITGB1

3.86e-05569222445342
Pubmed

Both ICAM-1- and VCAM-1-integrin interactions are important in mediating monocyte adhesion to human saphenous vein.

ITGB1 ITGB2

3.86e-05569212097820
Pubmed

Filamin B deficiency in mice results in skeletal malformations and impaired microvascular development.

FLNA FLNB

3.86e-05569217360453
Pubmed

Prediction of the coding sequences of unidentified human genes. XIII. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro.

STXBP5L FRMPD1 CNOT1 SEZ6L

5.21e-0510269410231032
Pubmed

Adhesion of human haematopoietic (CD34+) stem cells to human liver compartments is integrin and CD44 dependent and modulated by CXCR3 and CXCR4.

ITGB1 ITGB2

5.79e-05669219703720
Pubmed

RanBPM is a phosphoprotein that associates with the plasma membrane and interacts with the integrin LFA-1.

ITGB1 ITGB2

5.79e-05669214722085
Pubmed

Vector-capping: a simple method for preparing a high-quality full-length cDNA library.

FLNA FLNB

5.79e-05669216106752
Pubmed

Cytohesin-1 controls the activation of RhoA and modulates integrin-dependent adhesion and migration of dendritic cells.

ITGB1 ITGB2

5.79e-05669219346499
Pubmed

ASB2 targets filamins A and B to proteasomal degradation.

FLNA FLNB

5.79e-05669218799729
Pubmed

HIV-1-Tat protein promotes chemotaxis and invasive behavior by monocytes.

ITGB1 ITGB2

5.79e-0566928757599
Pubmed

Trisomy 12 chronic lymphocytic leukemia cells exhibit upregulation of integrin signaling that is modulated by NOTCH1 mutations.

ITGB1 ITGB2

5.79e-05669224829201
Pubmed

Rapid leukocyte migration by integrin-independent flowing and squeezing.

ITGB1 ITGB2

5.79e-05669218451854
Pubmed

Macrophage network dynamics depend on haptokinesis for optimal local surveillance.

ITGB1 ITGB2

5.79e-05669235343899
Pubmed

Binding of paxillin to alpha4 integrins modifies integrin-dependent biological responses.

FLNA ITGB1

5.79e-05669210604475
Pubmed

The AMPA receptor GluR2 C terminus can mediate a reversible, ATP-dependent interaction with NSF and alpha- and beta-SNAPs.

NAPB GRIA3

5.79e-0566929697855
Pubmed

HDLBP Promotes Hepatocellular Carcinoma Proliferation and Sorafenib Resistance by Suppressing Trim71-dependent RAF1 Degradation.

LUC7L FLNA NEDD4L AHR SDF4 RPS23 CHD1L SUCLG2 ITGB1 CNOT1 VDAC3

7.66e-051371691136244648
Pubmed

Association of human platelet alloantigen 1 through 5 polymorphisms with ischemic stroke.

ITGB1 ITGB2

8.09e-05769218057877
Pubmed

Phosphoinositide-3-OH kinase-dependent regulation of glycogen synthase kinase 3 and protein kinase B/AKT by the integrin-linked kinase.

ITGB1 ITGB2

8.09e-0576929736715
Pubmed

Multimolecular signaling complexes enable Syk-mediated signaling of CD36 internalization.

ITGB1 ITGB2

8.09e-05769223395392
Pubmed

A point mutation in KINDLIN3 ablates activation of three integrin subfamilies in humans.

ITGB1 ITGB2

8.09e-05769219234460
Pubmed

Meta-analysis of genome-wide association studies from the CHARGE consortium identifies common variants associated with carotid intima media thickness and plaque.

LRIG1 SLC17A4

1.08e-04869221909108
Pubmed

Lrig1 expression defines a distinct multipotent stem cell population in mammalian epidermis.

LRIG1 ITGB1

1.08e-04869219427292
Pubmed

MEKK4 signaling regulates filamin expression and neuronal migration.

FLNA FLNB

1.08e-04869217145501
Pubmed

Filamin B mutations cause chondrocyte defects in skeletal development.

FLNA FLNB

1.08e-04869217510210
Pubmed

Expression patterns of beta1-related alpha integrin subunits in murine lens during embryonic development and wound healing.

ITGB1 ITGB2

1.08e-04869215370361
Pubmed

Filamin-A regulates actin-dependent clustering of HIV receptors.

FLNA LIMK2

1.08e-04869217572668
Pubmed

The LIM-only protein DRAL/FHL2 binds to the cytoplasmic domain of several alpha and beta integrin chains and is recruited to adhesion complexes.

ITGB1 ITGB2

1.08e-04869210906324
Pubmed

An SH3 domain-containing GTPase-activating protein for Rho and Cdc42 associates with focal adhesion kinase.

ITGB1 ITGB2

1.08e-0486928649427
Pubmed

Discovery of a Human Testis-specific Protein Complex TEX101-DPEP3 and Selection of Its Disrupting Antibodies.

FLNB ACP3 APOD ITGB1 ITGB2

1.40e-0424969530097533
Pubmed

Filamin B regulates chondrocyte proliferation and differentiation through Cdk1 signaling.

FLNB ITGB1

1.73e-041069224551245
Pubmed

Filamin-interacting proteins, Cfm1 and Cfm2, are essential for the formation of cartilaginous skeletal elements.

FLNA FLNB

1.73e-041069224436304
Pubmed

Cytoskeletal Associated Filamin A and RhoA Affect Neural Progenitor Specification During Mitosis.

FLNA ITGB1

1.73e-041069229462287
Pubmed

Large-scale proteomics and phosphoproteomics of urinary exosomes.

A1BG FLNA FLNB EYS ACP3 NAGLU APOD ITGB1 VDAC3

1.76e-04101669919056867
Pubmed

Transcriptome of the inner circular smooth muscle of the developing mouse intestine: Evidence for regulation of visceral smooth muscle genes by the hedgehog target gene, cJun.

FLNA HHIP LRIG1 ADAMTS8

1.77e-0414069426930384
Pubmed

Mouse endothelial OTUD1 promotes angiotensin II-induced vascular remodeling by deubiquitinating SMAD3.

FLNA FLNB

2.11e-041169236579465
Cytoband17q21

C1QL1 AOC2 NAGLU

1.21e-046369317q21
CytobandEnsembl 112 genes in cytogenetic band chr8p21

PPP2R2A LZTS1 SLC39A14

1.13e-03135693chr8p21
CytobandEnsembl 112 genes in cytogenetic band chr3p14

FLNB LRIG1 SUCLG2

1.26e-03140693chr3p14
GeneFamilyCD molecules|Integrin beta subunits

ITGB1 ITGB2

1.79e-0494121159
ToppCellwk_08-11-Mesenchymal-Myofibro_&_SMC-Late_airway_SMC|wk_08-11 / Celltypes from embryonic and fetal-stage human lung

COL4A6 FLNA HHIP LRIG1 RBKS ADAMTS8

2.05e-071636961e8730d75cccf7292010683ab4e81a69d8e3bfa9
ToppCellMacroglial-Polydendrocytes-PDGFRA-|Macroglial / cells hierarchy compared to all cells using T-Statistic

C1QL1 ARHGAP10 STXBP5L STK32B GRIA3 SEZ6L

6.80e-07200696f17b5a54e8f9eba9dcd0808ba4e8d275ac41bce2
ToppCellMacroglial-Polydendrocytes-PDGFRA--|Macroglial / cells hierarchy compared to all cells using T-Statistic

C1QL1 ARHGAP10 STXBP5L STK32B GRIA3 SEZ6L

6.80e-07200696cc3409518f8b436ea92deb955e81114b3f410ff7
ToppCellMacroglial-Polydendrocytes-PDGFRA|Macroglial / cells hierarchy compared to all cells using T-Statistic

C1QL1 ARHGAP10 STXBP5L STK32B GRIA3 SEZ6L

6.80e-07200696c24a3099e3d96d8b72f6d05286bb355d661a0377
ToppCellMacroglial-Polydendrocytes-PDGFRA---|Macroglial / cells hierarchy compared to all cells using T-Statistic

C1QL1 ARHGAP10 STXBP5L STK32B GRIA3 SEZ6L

6.80e-072006964fc3de4bff7ed2bf40b38462c4b4e9b87af6a4ca
ToppCellMacroglial-Polydendrocytes-PDGFRA----L1-6|Macroglial / cells hierarchy compared to all cells using T-Statistic

C1QL1 ARHGAP10 STXBP5L STK32B GRIA3 SEZ6L

6.80e-07200696310cd53db1c137f6af74e6ae682221d7ac27310c
ToppCellMacroglial-Polydendrocytes|Macroglial / cells hierarchy compared to all cells using T-Statistic

C1QL1 ARHGAP10 STXBP5L STK32B GRIA3 SEZ6L

6.80e-07200696961858738ce35db8760c8c2e136f8369bc444ccf
ToppCellfacs-Marrow-Granulocytes-18m-Hematologic-megakaryocyte-erythroid_progenitor_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DENND2A ANKRD42 AOC2 ERMAP RBKS

5.00e-0616069556e6f4b82b5dc41c45f9d253c2db314a6f702b84
ToppCellfacs-Marrow-Granulocytes-18m-Hematologic-megakaryocyte-erythroid_progenitor_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DENND2A ANKRD42 AOC2 ERMAP RBKS

5.00e-06160695bb1b966fb9e801db15e67d03e49db4609d6f935a
ToppCellMild/Remission-B_memory-6|World / disease group and sub_cluster of B and Plasma cells(res = 0.5)

FLNA FLNB UCKL1 ITGB1 ITGB2

5.98e-0616669503e1a369d8a83b814def07e29cabb023226b4828
ToppCellMild/Remission-B_memory-6|Mild/Remission / disease group and sub_cluster of B and Plasma cells(res = 0.5)

FLNA FLNB UCKL1 ITGB1 ITGB2

8.16e-061776958f2ce5ffc94ca90412cb6899629f322dc778215c
ToppCellSomatosensory_Cortex_(S1)-Non-neuronal-Macroglial-Oligo-OPC|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

C1QL1 DENND2A STK32B PON2 APOD

9.34e-061826958a8b08ac4bb3cba3541dbe234e088703842285b9
ToppCellAnterior_Cingulate_gyrus_(CgG)-Non-neuronal-Macroglial-Oligo-OPC|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

C1QL1 STK32B PON2 APOD SEZ6L

9.34e-061826953cc61f5f7ad4a81eba3daf65e122880b5af3adc0
ToppCellAnterior_Cingulate_gyrus_(CgG)-Non-neuronal-Macroglial-Oligo-OPC-OPC_L1-6_MYT1|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

C1QL1 STK32B PON2 APOD SEZ6L

9.34e-061826955d909e4b5f662905bf1be9c686bbddc3e87d2be9
ToppCellSomatosensory_Cortex_(S1)-Non-neuronal-Macroglial-Oligo-OPC-OPC_L1-6_MYT1|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

C1QL1 DENND2A STK32B PON2 APOD

9.34e-06182695e36766309c4d96a90d213ce37d3acef1029a3fdc
ToppCell3'-Adult-LargeIntestine-Mesenchymal-fibroblastic-Stromal_2_(NPY+)|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

A1BG C1QL1 HHIP CEBPD APOD

1.04e-05186695d3509a579871ba6a8c4edd6137b28f271c9dbe70
ToppCellPCW_05-06-Mesenchymal-Mesenchymal_myocytic-mes_ASM_(13)|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung

FLNA HHIP LRIG1 PIPOX ADAMTS8

1.09e-0518869574f7d216209cabdc96b2d46685b0ae017fdcc8fc
ToppCellFetal_29-31_weeks-Mesenchymal-airway_smooth_muscle_cell|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

DENND2A FLNA HHIP ADAMTS8 ITGB1

1.09e-051886954d1e5f85342ae550086609d7680e32730b78b5d2
ToppCellMesenchymal-airway_smooth_muscle_cell|World / Lineage, Cell type, age group and donor

COL4A6 DENND2A FLNA HHIP ADAMTS8

1.15e-05190695645e56b02edc3702c7db917b8ecd5eed0decaf71
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

DENND2A ACP3 PON2 ADGRF1 SLC35F5

1.15e-051906953fc9e18c7441c0ae8cda65753cc42d0520f4e116
ToppCellFetal_29-31_weeks-Epithelial-alveolar_epithelial_cell_type_2-D150|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

HHIP RAP1GAP NEDD4L PIK3C2G PON2

1.18e-0519169534cc997e4e5c727495f321e6807a84aa124da486
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Thick_Ascending_Limb_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

DENND2A ACP3 PON2 ADGRF1 SLC35F5

1.18e-051916955a67ff17fb4b9eff641176dff07830c9cd73754e
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

DENND2A ACP3 PON2 ADGRF1 SLC35F5

1.18e-0519169555ab2854a02cdcfc395e49870ccb7290b5e5471d
ToppCellFetal_29-31_weeks-Epithelial-alveolar_epithelial_cell_type_2|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

HHIP RAP1GAP NEDD4L PIK3C2G PON2

1.21e-05192695fb2f0e897228f808d9ff734ad05e9b49dc38fa50
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

DENND2A ACP3 PON2 ADGRF1 SLC35F5

1.24e-05193695263d185af6ed80e639f864e4966268e0862c61dc
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

DENND2A ACP3 PON2 ADGRF1 SLC35F5

1.24e-0519369580e058c224749b5fe0ba3e944b48317c2371cb63
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Thick_Ascending_Limb_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

DENND2A ACP3 PON2 ADGRF1 SLC35F5

1.24e-05193695b991fbbb4618401624f0b3045f0e81a606d3a763
ToppCellCV-Mild|CV / Virus stimulation, Condition and Cluster

A1BG IL16 RPS23 HERC5 RIC3

1.27e-051946950ce0376c12d8a2ca617f96dd1b7874393238d5a9
ToppCell5'-GW_trimst-2-LargeIntestine-Mesenchymal-fibroblastic-Stromal_2_(NPY+)|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

COL4A6 HHIP CEBPD APOD ITGB1

1.37e-05197695ea746772adb9df4ddb0508d4ef35f2027bf09c35
ToppCellNon-neuronal-Non-dividing-Radial_Glia-tRG|World / Primary Cells by Cluster

C1QL1 COL4A6 FLNA LRIG1 RPGR

1.37e-0519769561749ccafeb938c310cff1de5ff924a1c794325a
ToppCell356C-Epithelial_cells-Epithelial-A_(AT2)|Epithelial_cells / Donor, Lineage, Cell class and subclass (all cells)

HHIP CEBPD PON2 RPS23 SPG21

1.37e-051976950de77f04612b66cc637dab5d5432c6e711e5964e
ToppCellNon-neuronal-Non-dividing-Radial_Glia-tRG-25|World / Primary Cells by Cluster

C1QL1 COL4A6 FLNA LRIG1 RPGR

1.37e-051976959d4ffa3680f92c91d0a081f9a8ec5ebfec6bdcf6
ToppCellBrain_organoid-organoid_Paulsen_bioRxiv-6_mon-Macroglial|6_mon / Sample Type, Dataset, Time_group, and Cell type.

C1QL1 FLNA CEBPD LRIG1 PON2

1.37e-05197695965d5a3f8c9b12cb8a8d3429702ae29ebd8c6122
ToppCellBrain_organoid-organoid_Paulsen_bioRxiv-6_mon-Macroglial-Astroglia|6_mon / Sample Type, Dataset, Time_group, and Cell type.

C1QL1 FLNA CEBPD LRIG1 PON2

1.37e-051976953f088eb29197bc575400d6dafd8083e69e4a149f
ToppCell356C-Epithelial_cells-Epithelial-A_(AT2)-|Epithelial_cells / Donor, Lineage, Cell class and subclass (all cells)

HHIP CEBPD PON2 RPS23 SPG21

1.37e-05197695a01640e31fc33c1ab512b4d3eddae8342ecf182c
ToppCellwk_08-11-Mesenchymal-Myofibro_&_SMC|wk_08-11 / Celltypes from embryonic and fetal-stage human lung

COL4A6 FLNA HHIP LRIG1 ADAMTS8

1.40e-05198695637f11e292b90d86cdc0d0d828eb26f38289c25b
ToppCellwk_15-18-Mesenchymal-Myofibro_&_SMC-Late_airway_SMC|wk_15-18 / Celltypes from embryonic and fetal-stage human lung

COL4A6 FLNA HHIP LRIG1 ADAMTS8

1.40e-051986952d0c14f8cabab99bc6d7c27685437c78841c7245
ToppCelldroplet-Limb_Muscle-nan-24m-Mesenchymal-skeletal_muscle_satellite_cell|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CEBPD NEDD4L MIP RPS23 SLC39A14

1.40e-05198695d5e91d1057e71b6a336eec95e44b2e7fe6b2c6ef
ToppCell3'-Pediatric_IBD-SmallIntestine-Mesenchymal-fibroblastic-Stromal_2_(NPY+)|Pediatric_IBD / Celltypes from developing, pediatric, Crohn's, & adult GI tract

C1QL1 COL4A6 CEBPD APOD ITGB1

1.44e-05199695ec74ff85d6b61013b1f785b2fca343759feb7843
ToppCellwk_08-11-Mesenchymal-Myofibro_&_SMC-Early_airway_SMC_2|wk_08-11 / Celltypes from embryonic and fetal-stage human lung

COL4A6 FLNA HHIP LRIG1 ADAMTS8

1.44e-05199695a207b4891881149d4c50721310690fd794157723
ToppCellLPS_anti-TNF-Mesenchymal_myocytic-Myofibroblastic-MatrixFB_->_Myofibroblast|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type

C1QL1 DENND2A FLNA HHIP GRIA3

1.44e-0519969538cfd367ee8c074c11ba54edeb7a001e375e2687
ToppCellParenchymal-NucSeq-Stromal-Myofibroblastic-Muscle_smooth_systemic_arterial|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

DENND2A WDR87 MIP ADAMTS8 SLC39A14

1.44e-05199695b768496381362f9a2706e0892b5a7a0db82e09ce
ToppCellkidney_cells-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

ACP3 PON2 ADGRF1 ITGB1 SLC35F5

1.44e-051996952e7f517c0444b4f29ff11c26ab32e9cc0f7e99ef
ToppCellLPS_IL1RA_TNF-Mesenchymal_myocytic|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type

C1QL1 DENND2A FLNA HHIP LZTS1

1.47e-05200695f599e4b051ac3dad11ad437e98dc8ea6754cca53
ToppCellkidney_cells-Renal_AKI_(acute_kidney_injury)-Epithelial-Intermediate_tubule_epithelial_cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

DENND2A PON2 ADGRF1 ITGB1 SLC35F5

1.47e-05200695ae91dc047dc80560ba298d8d21a772154fa2775d
ToppCellmLN-Dendritic_cell-cDC2|Dendritic_cell / Region, Cell class and subclass

LONRF1 AHR SUCLG2 ITGB2 SPG21

1.47e-05200695e3f7852aaa26a9b3e626d85e40afde799e873045
ToppCellkidney_cells-Renal_AKI_(acute_kidney_injury)-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

DENND2A PON2 ADGRF1 ITGB1 SLC35F5

1.47e-05200695d9dab2aed11e45c60d11ff0c5af1f2fbb9cb45d8
ToppCellLPS_IL1RA_TNF-Mesenchymal_myocytic-Myofibroblastic-MatrixFB_->_Myofibroblast|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type

C1QL1 DENND2A FLNA HHIP GRIA3

1.47e-0520069509537dc25f8b8b4654a7c183827ee1522a41a4e0
ToppCellkidney_cells-Renal_AKI_(acute_kidney_injury)-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Thick_Ascending_Limb_Cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

DENND2A PON2 ADGRF1 ITGB1 SLC35F5

1.47e-0520069533b7af6c50e65dc1bdf429572574ed072f8bc29f
ToppCellLPS_anti-TNF-Mesenchymal_myocytic|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type

C1QL1 DENND2A FLNA HHIP LZTS1

1.47e-0520069567dcbd86fbc79fd585d0793f979e4aac100326c9
ToppCellFetal_brain-organoid_Tanaka_cellReport-GW16-Macroglial-Glia_progenitor_cell|GW16 / Sample Type, Dataset, Time_group, and Cell type.

C1QL1 LRIG1 PIK3C2G APOD SUCLG2

1.47e-052006956c1b7b0f3cd35d8cfee181ea83c73127dbc41ac5
ToppCellFetal_brain-organoid_Tanaka_cellReport-GW23-Macroglial-Astrocyte|GW23 / Sample Type, Dataset, Time_group, and Cell type.

C1QL1 RAP1GAP PON2 APOD SEZ6L

1.47e-052006954fe3b2d80c567c18621bff3341f9a73578c81621
ToppCellControl-Classical_Monocyte-|Control / Disease condition and Cell class

LRIG1 ARHGAP10 AHR RBKS

4.97e-05130694e55f522dab5a6c3af30ad87ac8b32166f660c314
ToppCellLymphoid-Lymphoid-NK_cells|Lymphoid / shred on cell class and cell subclass (v4)

ANKRD42 GRIA3 ITGB1 ITGB2

8.23e-05148694d51a4b654a88d58dcdf29c2bc362c0cc1c40723a
ToppCell10x5'-bone_marrow-Lymphocytic_B-Pro-B|bone_marrow / Manually curated celltypes from each tissue

HHIP LRIG1 STK32B ADGRF1

9.60e-051546948a8c3851888ab86ca2b13ccc042cde1fef8d88f8
ToppCell10x5'-GI_small-bowel-Lymphocytic_T_CD4-Teffector/EM_CD4|GI_small-bowel / Manually curated celltypes from each tissue

ACP3 RPS23 ITGB1 ITGB2

1.01e-04156694e308328f560c5ee7e9f95ac5db162f2d821ca39c
ToppCellChildren_(3_yrs)-Epithelial-basal_cell-D032|Children_(3_yrs) / Lineage, Cell type, age group and donor

COL4A6 NEDD4L LRIG1 WDR87

1.03e-041576946ee2692f705bdd93ba523dffaf2f0cd921b47e28
ToppCellPBMC-Control-Myeloid-cDC-cDC-cDC_1|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

ACP3 PON2 HERC5 SEZ6L

1.06e-04158694216b3f482daa2d0d7fcaf5a8559e3ccbdb8e110d
ToppCellPBMC-Control-Myeloid-cDC-cDC-cDC_1|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

ACP3 PON2 HERC5 SEZ6L

1.06e-041586949712bb8b1bacb8a38c99a22bc2babec5d5160e2a
ToppCellAnterior_Cingulate_gyrus_(CgG)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_D_(IT_RORB_THEMIS_LINC00507)_3-Exc_L3_LINC00507_PSRC1|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

EYS CEBPD PIK3C2G ARHGAP10

1.25e-041656946de69b75174731931e7e80a3488f983a7ba4defe
ToppCellfacs-Marrow-Granulocytes-3m-Myeloid-granulocyte|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FLNA CEBPD ACP3 ITGB2

1.44e-04171694ab21f20ec041cbaacccbd7da4dccdb77ec8bc5c6
ToppCellfacs-Marrow-Granulocytes-3m-Myeloid-granulocyte|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FLNA CEBPD ACP3 ITGB2

1.44e-0417169497ad2cfff568a9d006ab1d2e6e00946ee4e3beb3
ToppCelldroplet-Marrow-BM-1m-Myeloid-granulocyte|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DENND2A ACP3 ITGB2 ELOVL7

1.44e-041716948a0c08f0aa3a80cd6346c81deb242e430ebd897b
ToppCellfacs-Marrow-T-cells-24m-Myeloid-CD4+_macrophage|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

STK32B GRIA3 APOD SLC39A14

1.50e-04173694ca3d2a9562734f76127e3e7d54c10b63e95141bb
ToppCellfacs-Marrow-T-cells-24m-Myeloid-macrophage|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

STK32B GRIA3 APOD SLC39A14

1.50e-0417369419a9e10885173d7712996be8660a3a5a7a9aa39f
ToppCell5'-Parenchyma_lung-Immune_Myeloid-Myeloid_macrophage-alveolar_macrophage-Alveolar_macrophages-Alveolar_macrophages_L.1.0.5.0|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

FLNA CHD1L ITGB2 SEZ6L

1.54e-04174694d5c22b43531414951666ee7542a66ed9380e2d14
ToppCell3'-Adult-LymphNode-Mesenchymal-Pericytes-Contractile_pericyte_(PLN+)|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

COL4A6 FLNA FRMPD1 PIPOX

1.60e-0417669456e19240f4a7b617a986e3c0854b757394e78251
ToppCell3'-Adult-LymphNode-Mesenchymal-Pericytes|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

COL4A6 FLNA FRMPD1 PIPOX

1.60e-04176694c88b46fe29ae7606c8880a6ff0ebb85c0dfda8bd
ToppCellfacs-Marrow-Granulocytes-3m-Myeloid|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FLNA CEBPD ACP3 ITGB2

1.64e-04177694065bebd22031f143e90a407f952b444a3f8818c7
ToppCellfacs-Kidney-nan-24m-Epithelial-kidney_collecting_duct_epithelial_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PRODH2 STXBP5L SLC17A4 PIPOX

1.64e-041776949c7c6824b9011363851f084a500d665f025b026e
ToppCellfacs-Marrow-Granulocytes-3m|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FLNA CEBPD ACP3 ITGB2

1.64e-04177694eb304f20aab075bd17aa3aef819386c0e1a235bd
ToppCellfacs-Kidney-nan-24m-Epithelial-kidney_collecting_duct_epithelial_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PRODH2 STXBP5L SLC17A4 PIPOX

1.64e-041776942bf639e9e801e5144462ffc957f5739e0dfcd500
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Medullary_Thick_Ascending_Limb_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

DENND2A RAP1GAP ACP3 STK32B

1.68e-04178694dfed0fbf7a73b8a9e00178ec58dc4592b271c344
ToppCellcellseq2-Mesenchymal-Fibroblastic-Fibroblastic_2-ASMC|cellseq2 / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

COL4A6 DENND2A FLNA ADAMTS8

1.68e-041786948ec2a25dda96c9cc9c2904b6cb18f75a293f4969
ToppCellcellseq2-Mesenchymal-Fibroblastic-Fibroblastic_2|cellseq2 / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

COL4A6 DENND2A FLNA ADAMTS8

1.68e-041786946c91331196696e0cf239d105f458e3230659fa38
ToppCell390C-Epithelial_cells-Epithelial-B_(AT2)|390C / Donor, Lineage, Cell class and subclass (all cells)

HHIP CEBPD PON2 ADGRF1

1.71e-04179694466da2bc3bfc534ffe111c8c28ece7a3cfa08051
ToppCell390C-Epithelial_cells-Epithelial-B_(AT2)-|390C / Donor, Lineage, Cell class and subclass (all cells)

HHIP CEBPD PON2 ADGRF1

1.71e-04179694f4bdebb77d39e63160fbf3a85a340ce4d52b7cfd
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

DENND2A RAP1GAP ACP3 STK32B

1.71e-04179694d0fa700648db8ce76a8aa689879a25048299fa40
ToppCell3'-Adult-LargeIntestine-Epithelial-neuro-epithelial-EC_cells_(TAC1+)|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

EYS STXBP5L SERGEF APOD

1.71e-04179694878b15ea62e3405682a538f79f58d74b9cd3f398
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Epithelial-Distal_tubule_epithelial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

DENND2A RAP1GAP ACP3 STK32B

1.71e-041796942e49b215b71438400aebb483f2c2c08d5e956961
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Distal_tubule_epithelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

DENND2A RAP1GAP ACP3 STK32B

1.75e-04180694eee71184ebed2694d3e60f579a44b3cf7dd2cd35
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

DENND2A RAP1GAP ACP3 STK32B

1.75e-04180694a17dbe03597b81e7a1fe2bf2d23e59e55c615a2a
ToppCell5'-GW_trimst-1.5-LargeIntestine-Mesenchymal-myocytic-myofibroblast_(RSPO2+)|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

FLNA HHIP LRIG1 ADAMTS8

1.82e-0418269437547b36264090b49a193a8ef3a8d88e647f0b79
ToppCellPrimary_Motor_Cortex_(M1)-Non-neuronal-Macroglial-Oligo-OPC-OPC_L1-6_MYT1|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

C1QL1 STK32B PON2 APOD

1.82e-04182694a05e5978ef5f7fac7eeb2ba1c0103ea90d5e9136
ToppCell3'-GW_trimst-2-LargeIntestine-Mesenchymal-myocytic|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

FLNA HHIP ADAMTS8 ITGB1

1.82e-04182694728a2152c166551ac229370c0900fe2bc426ea9b
ToppCellPrimary_Motor_Cortex_(M1)-Non-neuronal-Macroglial-Oligo-OPC|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

C1QL1 STK32B PON2 APOD

1.82e-04182694831b5ce46b41efe01c4db6016c2f43148611373d
ToppCellPBMC_fresh-frozen-Severe-critical_progression_d12-22_no-steroids-Myeloid-Dendritic-conventional_dendritic_cell-DC_c2-CD1C|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)

CEBPD ACP3 PON2 SEZ6L

1.82e-04182694c3fb1460160744144aa31afc76c0a4d42ebdeb91
ToppCellwk_15-18-Mesenchymal-Myofibro_&_SMC-Early_airway_SMC_2|wk_15-18 / Celltypes from embryonic and fetal-stage human lung

COL4A6 FLNA HHIP ADAMTS8

1.86e-04183694a1d4f25e13f5b9e92a9ca0a804a7bed5df8fb2fe
ToppCellCOPD-Epithelial-ATII|World / Disease state, Lineage and Cell class

HHIP RAP1GAP NEDD4L AHR

1.86e-041836948e9aab4eeec2e282c2cab9bfca6dbf40d660c7b9
ToppCellfacs-Brain_Non-Myeloid-Cortex_-18m-Macroglial-Oligodendrocyte_progenitor_cell|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

C1QL1 RAP1GAP GRIA3 SEZ6L

1.90e-04184694278a7ed764c326450cb70e69ed2175980eaf5fe0
ToppCellremission-CD8+_T_naive|remission / disease stage, cell group and cell class

A1BG FLNB RPS23 RIC3

1.90e-04184694fe20fa4457d4a4a75689978275b0afb5f6243faf
ToppCellfacs-Brain_Non-Myeloid-Cortex_-18m-Macroglial-oligodendrocyte_precursor_cell|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

C1QL1 RAP1GAP GRIA3 SEZ6L

1.90e-041846948d86e125257ff1d3af8d90577a8b3f0321eca21c
ToppCellprimary_auditory_cortex_(A1C)-Non-neuronal-Macroglial-Oligo-OPC-OPC_L1-6_MYT1|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

C1QL1 STK32B PON2 APOD

1.94e-04185694efc5d564f8793c751ba640aef60f761e4b081d3f
ToppCellLPS-antiTNF-Stromal_mesenchymal-Lung_smooth_muscle-MatrixFB_->_Myofibroblast|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

C1QL1 DENND2A HHIP GRIA3

1.94e-041856946712512100ccef456d2e2bd201d0987986c92ac9
ToppCellIPF-Epithelial-ATII|IPF / Disease state, Lineage and Cell class

HHIP RAP1GAP NEDD4L AHR

1.94e-04185694563b4e6d92bb5d77a3829556116a8e99aebac615
ToppCellMid-temporal_gyrus_(MTG)-Non-neuronal-Macroglial-Oligo-OPC-OPC_L1-6_MYT1|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

C1QL1 STK32B PON2 APOD

1.94e-041856942e1766f1a972fecd670daaaf7eb2d3a404f121e7
ToppCellMid-temporal_gyrus_(MTG)-Non-neuronal-Macroglial-Oligo-OPC|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

C1QL1 STK32B PON2 APOD

1.94e-041856947aaa8335b40927e3e8fdcede807cd521fc213a0d
ToppCellCOVID-19_Convalescent-CD8+_T_naive|COVID-19_Convalescent / Disease condition and Cell class

A1BG FLNB RPS23 RIC3

1.94e-041856942f8277a0b58fb0c49fa76ff6dfa6da961da1f9f5
ToppCellprimary_auditory_cortex_(A1C)-Non-neuronal-Macroglial-Oligo-OPC|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

C1QL1 STK32B PON2 APOD

1.94e-04185694fba2dc46cd98ab9c78e788959c2121aa10d148b2
ToppCellEndothelial-B-Donor_07|World / lung cells shred on cell class, cell subclass, sample id

DENND2A FLNB STK32B SLC39A14

1.94e-04185694133c9dc64d564dae4aeeeca22f386aa3f13fa980
Diseasemyofibrillar myopathy 5 (implicated_via_orthology)

FLNA FLNB

1.61e-053692DOID:0080096 (implicated_via_orthology)
DiseasePeriventricular Heterotopia, X-Linked

FLNA NEDD4L

1.61e-053692C1848213
Diseasedistal muscular dystrophy 4 (implicated_via_orthology)

FLNA FLNB

1.61e-053692DOID:0111190 (implicated_via_orthology)
DiseaseBilateral Periventricular Nodular Heterotopia

FLNA NEDD4L

1.61e-053692C4551969
Diseaseperiventricular nodular heterotopia (is_implicated_in)

FLNA NEDD4L

8.03e-056692DOID:0050454 (is_implicated_in)
DiseasePeriventricular Nodular Heterotopia

FLNA NEDD4L

1.12e-047692C1868720
Diseasepost-operative sensory disturbance

STK32B AHR

1.92e-049692EFO_0005324
Diseasemyopathy (implicated_via_orthology)

COL4A6 FLNA FLNB

1.96e-0448693DOID:423 (implicated_via_orthology)
Diseaseresponse to carboplatin, response to antineoplastic agent

FLNB LRIG1

2.40e-0410692GO_0097327, GO_0097328
DiseaseEndometrioma

NEDD4L SUCLG2 ITGB1 HERC5

5.60e-04161694C0269102
DiseaseEndometriosis

NEDD4L SUCLG2 ITGB1 HERC5

5.60e-04161694C0014175
Diseaseosteochondrodysplasia (is_implicated_in)

FLNA FLNB

8.98e-0419692DOID:2256 (is_implicated_in)
DiseaseBehcet Syndrome

AHR ITGB2

1.44e-0324692C0004943
DiseaseRetinitis Pigmentosa

EYS AHR RPGR

1.88e-03104693C0035334
DiseaseEarly Pregnancy Loss

COL4A6 IL16 AHR

2.15e-03109693C3830362
DiseaseMiscarriage

COL4A6 IL16 AHR

2.15e-03109693C4552766
DiseaseSpontaneous abortion

COL4A6 IL16 AHR

2.15e-03109693C0000786
DiseaseAbortion, Tubal

COL4A6 IL16 AHR

2.15e-03109693C0000822
DiseaseLiver Cirrhosis, Experimental

FLNA PRODH2 LIMK2 CEBPD TCF20 ITGB1 ITGB2

2.19e-03774697C0023893
DiseaseEpileptic encephalopathy

FLNA NEDD4L

2.25e-0330692C0543888
Diseasevital capacity

USP34 DENND2A HHIP TCF20 LZTS1 FRMPD1 AHR ADAMTS8 SUCLG2

2.28e-031236699EFO_0004312

Protein segments in the cluster

PeptideGeneStartEntry
KNFSAGGHKVGLGFE

VDAC3

266

Q9Y277
NSFAGGHPGLFQDSK

AHR

521

P35869
LAGLFGAAEGQAFHL

APOD

11

P05090
LQGLTGHKGFLGDSG

COL4A6

766

Q14031
GFHQEVFLGKDLGGF

SDF4

76

Q9BRK5
FNHSGELLATGDKGG

PPP2R2A

36

P63151
DGHGGFLGKNDGIKT

ADGRF1

16

Q5T601
GELALHLSAFGKGFV

ADAMTS8

51

Q9UP79
FIKLDGGKAHGGNSN

C1QL1

231

O75973
MLHNFGGNHGLFGAL

NAGLU

406

P54802
LAFPGHVAAFKGDLG

ANKRD42

236

Q8N9B4
QSLSFDGGAFHLKGT

PRODH2

96

Q9UF12
ALAVGFSLALGHLFG

MIP

161

P30301
AGTKLFIHGGLAGDR

RABEPK

201

Q7Z6M1
GFHFAGDGKLGGIVL

ITGB1

281

P05556
DFGKFLGHAQTFGGI

PIK3C2G

1051

O75747
TIHGHKFFIGFGGKG

RBKS

41

Q9H477
RIFFHLNAVALGDGG

A1BG

261

P04217
TAFLKGGEEGLLFGN

AOC2

491

O75106
GPDKNHLLADGGSFG

ARHGAP10

656

A1A4S6
LLRFGFSQDSGHGKS

LZTS1

41

Q9Y250
LADHFGGKLHLGFIQ

LUC7L

206

Q9NQ29
LIFFTGQKGHGLNGD

EYS

2461

Q5T1H1
AFSGLEGLEHLNLGG

LRIG1

401

Q96JA1
LIHGEVLGKGFFGQA

LIMK2

331

P53671
GGHLKGALEAFAAAL

LONRF1

61

Q17RB8
FFLVLGLLGHSHGGF

GRIA3

16

P42263
FQFTVGPLGEGGAHK

FLNB

2181

O75369
LHKEEGAGLGFSLAG

IL16

1116

Q14005
HLAEAFAKAKGSGGG

RIC3

71

Q7Z5B4
DGLLFTFGAGKHGQL

HERC5

261

Q9UII4
LGKLSGLHGQDLFGI

ACP3

191

P15309
GLAFFSVGLKFPGLH

PON2

61

Q15165
GFHFAGDGKLGAILT

ITGB2

266

P05107
FNSNHKAGGAGPLEL

CEBPD

86

P49716
SGEHSGVNKFLKGLG

DENND2A

986

Q9ULE3
GVKFAAGGLGTFHAL

ELOVL7

161

A1L3X0
FQFTVGPLGEGGAHK

FLNA

2226

P21333
AGGSAHGKLFPGDQI

FRMPD1

86

Q5SYB0
GGHFTLGAQKPAADA

CHD1L

496

Q86WJ1
FDGHGGIRASKFAAQ

ILKAP

151

Q9H0C8
GFLKGLLQVFAHIAG

SLC17A4

426

Q9Y2C5
LGLAFGILAGSHFSA

SLC39A14

411

Q15043
DGRHGKLGLGLENFT

RPGR

321

Q92834
AGDAGKFHVALLGGT

ERMAP

31

Q96PL5
FVCGLNKDGQLGLGH

SERGEF

71

Q9UGK8
FGGGAELLFDGIKKH

URM1

11

Q9BTM9
QFHSDPAGLIFGKGQ

SEZ6L

716

Q9BYH1
GLRGKHAAFFADAEG

SLC35F5

131

Q8WV83
FEDGHLSHFIDGKGG

PRDM14

306

Q9GZV8
YGGGAKLSHNGIFTL

PITRM1

906

Q5JRX3
FKGFRGGLDVTHGQT

RAP1GAP

236

P47736
DKVHLFGASLGGFLA

SPG21

101

Q9NZD8
KHLGGQLLFGPDGFL

HHIP

351

Q96QV1
EAQNRGFLKGLFGGS

STXBP5L

1076

Q9Y2K9
DHFQILRAIGKGSFG

STK32C

91

Q86UX6
SHLLFGQKGAFGVGQ

CNOT1

186

A5YKK6
HLGTALKANPFGGAS

RPS23

31

P62266
FLNGGKPANFLDLGG

SUCLG2

321

Q96I99
FLHGNSFDLGEDGGL

PYROXD1

326

Q8WU10
HGALGFLGGVLVALK

TMEM115

136

Q12893
VKASHSFLRGLFGGN

NAPB

21

Q9H115
HAAGFKGFGLEGVPE

TCF20

431

Q9UGU0
HGTQSKEAFAIGLGG

UCKL1

91

Q9NWZ5
DHFQILRAIGKGSFG

STK32B

21

Q9NY57
VIGAGFSGHGFKLAP

PIPOX

341

Q9P0Z9
GGKGFPFLFQHIRDG

USP34

2546

Q70CQ2
GHFNLGRGLEGLIFS

WDR87

426

Q6ZQQ6
VAGLAVFHGKLLDGF

NEDD4L

716

Q96PU5