Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionminus-end-directed microtubule motor activity

DYNC2H1 DNAH12 DNAH17 DNAH8 DYNC1H1

3.42e-08181085GO:0008569
GeneOntologyMolecularFunctionmicrotubule motor activity

KIF21B DYNC2H1 DNAH12 DNAH17 KIF13A DNAH8 DYNC1H1

1.01e-07701087GO:0003777
GeneOntologyMolecularFunctioncytoskeletal motor activity

KIF21B DYNC2H1 MYO3A DNAH12 DNAH17 KIF13A DNAH8 DYNC1H1

2.52e-071181088GO:0003774
GeneOntologyMolecularFunctiondynein light intermediate chain binding

DYNC2H1 DNAH12 DNAH17 DNAH8 DYNC1H1

3.75e-07281085GO:0051959
GeneOntologyMolecularFunctionATP-dependent activity

KIF21B ABCF3 IPO8 DYNC2H1 DHX38 WRNIP1 UBA3 CHD2 MYO3A DNAH12 DNAH17 CHD6 KIF13A DNAH8 DYNC1H1

1.09e-0661410815GO:0140657
GeneOntologyMolecularFunctiondynein intermediate chain binding

DYNC2H1 DNAH12 DNAH17 DNAH8 DYNC1H1

1.60e-06371085GO:0045505
GeneOntologyMolecularFunctioncalcium channel activity

CACNA1F CACNA1S TRPC4AP TRPC7 PKD1L2 CATSPER1 TRPV3

6.47e-061291087GO:0005262
GeneOntologyMolecularFunctioncalcium ion transmembrane transporter activity

CACNA1F CACNA1S TRPC4AP TRPC7 PKD1L2 CATSPER1 TRPV3

1.81e-051511087GO:0015085
GeneOntologyMolecularFunctionATP hydrolysis activity

KIF21B ABCF3 DYNC2H1 DHX38 WRNIP1 CHD2 DNAH12 CHD6 KIF13A DNAH8 DYNC1H1

2.71e-0544110811GO:0016887
GeneOntologyMolecularFunctionleucine-tRNA ligase activity

LARS1 LARS2

2.90e-0521082GO:0004823
GeneOntologyMolecularFunctionmetal ion transmembrane transporter activity

CACNA1F CACNA1S TRPC4AP TRPC7 SLC5A7 PKD1L2 TFRC CATSPER1 SLC12A1 TRPV3

2.15e-0446510810GO:0046873
GeneOntologyMolecularFunctionguanyl-nucleotide exchange factor activity

DOCK1 CCZ1B ARHGEF28 RAPGEF4 CCZ1 RAPGEF3 HERC1

2.62e-042311087GO:0005085
GeneOntologyMolecularFunctioninorganic cation transmembrane transporter activity

CACNA1F CACNA1S TRPC4AP TRPC7 SLC5A7 PKD1L2 NDUFS1 TFRC CATSPER1 SLC12A1 TRPV3

5.87e-0462710811GO:0022890
GeneOntologyMolecularFunctioninorganic molecular entity transmembrane transporter activity

CACNA1F CACNA1S TRPC4AP TRPC7 SLC5A7 PKD1L2 NDUFS1 TFRC CATSPER1 CLCN2 SLC12A1 TRPV3

8.15e-0475810812GO:0015318
GeneOntologyMolecularFunctionmonoatomic cation transmembrane transporter activity

CACNA1F CACNA1S TRPC4AP TRPC7 SLC5A7 PKD1L2 NDUFS1 TFRC CATSPER1 SLC12A1 TRPV3

9.39e-0466410811GO:0008324
GeneOntologyMolecularFunctionmonoatomic ion transmembrane transporter activity

CACNA1F CACNA1S TRPC4AP TRPC7 SLC5A7 PKD1L2 NDUFS1 TFRC CATSPER1 CLCN2 SLC12A1 TRPV3

1.20e-0379310812GO:0015075
GeneOntologyMolecularFunctionhistone H3K4 trimethyltransferase activity

SETD1A SMYD2

1.27e-03101082GO:0140999
GeneOntologyMolecularFunctiontransmembrane transporter activity

CACNA1F CACNA1S TRPC4AP TRPC7 IPO8 SLC5A7 PKD1L2 SLC29A2 NDUFS1 TFRC SIDT2 CATSPER1 CLCN2 SLC12A1 TRPV3

1.70e-03118010815GO:0022857
GeneOntologyMolecularFunctionvoltage-gated calcium channel activity

CACNA1F CACNA1S CATSPER1

1.97e-03461083GO:0005245
GeneOntologyMolecularFunctionaminoacyl-tRNA editing activity

LARS1 LARS2

2.53e-03141082GO:0002161
GeneOntologyMolecularFunctionhigh voltage-gated calcium channel activity

CACNA1F CACNA1S

2.53e-03141082GO:0008331
GeneOntologyMolecularFunctionmonoatomic cation channel activity

CACNA1F CACNA1S TRPC4AP TRPC7 PKD1L2 CATSPER1 TRPV3

2.63e-033431087GO:0005261
GeneOntologyCellularComponentdynein complex

DYNC2H1 DNAH12 DNAH17 DNAH8 DYNC1H1

8.67e-06541085GO:0030286
GeneOntologyCellularComponentmicrotubule associated complex

KIF21B DYNC2H1 DNAH12 DNAH17 KIF13A DNAH8 DYNC1H1

2.05e-051611087GO:0005875
GeneOntologyCellularComponentcilium

DRC7 CACNA1F DYNC2H1 TEDC2 RTTN RAPGEF4 EYS CATSPER1 DNAH12 GLE1 DNAH17 PKHD1 CFAP61 DNAH8

2.16e-0489810814GO:0005929
GeneOntologyCellularComponentguanyl-nucleotide exchange factor complex

DOCK1 CCZ1B CCZ1

2.51e-04241083GO:0032045
GeneOntologyCellularComponentMon1-Ccz1 complex

CCZ1B CCZ1

2.62e-0451082GO:0035658
GeneOntologyCellularComponentaxonemal dynein complex

DNAH12 DNAH17 DNAH8

2.84e-04251083GO:0005858
GeneOntologyCellularComponentbasal plasma membrane

INPPL1 RAPGEF4 SLC29A2 CHRM3 TFRC CLCN2 RAPGEF3 PLEC

5.06e-043541088GO:0009925
GeneOntologyCellularComponentbasal part of cell

INPPL1 RAPGEF4 SLC29A2 CHRM3 TFRC CLCN2 RAPGEF3 PLEC

7.76e-043781088GO:0045178
GeneOntologyCellularComponentapical part of cell

DYNC2H1 RAPGEF4 SLC5A7 SLC29A2 SLC12A1 RAPGEF3 PKHD1 LHFPL5 PLEC NOS3

9.90e-0459210810GO:0045177
GeneOntologyCellularComponent9+2 motile cilium

DYNC2H1 CATSPER1 DNAH12 DNAH17 CFAP61 DNAH8

1.49e-032381086GO:0097729
GeneOntologyCellularComponentouter dynein arm

DNAH17 DNAH8

1.69e-03121082GO:0036157
GeneOntologyCellularComponentvoltage-gated calcium channel complex

CACNA1F CACNA1S CATSPER1

1.73e-03461083GO:0005891
DomainGOLGA6L

GOLGA6L4 GOLGA6L10 GOLGA6L19 GOLGA6L9

1.82e-0861124IPR026737
DomainDynein_heavy_chain_D4_dom

DYNC2H1 DNAH12 DNAH8 DYNC1H1

1.17e-06141124IPR024317
DomainDynein_heavy_dom-2

DYNC2H1 DNAH12 DNAH8 DYNC1H1

1.17e-06141124IPR013602
DomainDHC_N2

DYNC2H1 DNAH12 DNAH8 DYNC1H1

1.17e-06141124PF08393
DomainATPase_dyneun-rel_AAA

DYNC2H1 DNAH12 DNAH8 DYNC1H1

1.17e-06141124IPR011704
DomainAAA_8

DYNC2H1 DNAH12 DNAH8 DYNC1H1

1.17e-06141124PF12780
DomainAAA_5

DYNC2H1 DNAH12 DNAH8 DYNC1H1

1.17e-06141124PF07728
DomainDHC_fam

DYNC2H1 DNAH12 DNAH8 DYNC1H1

1.59e-06151124IPR026983
DomainDynein_heavy

DYNC2H1 DNAH12 DNAH8 DYNC1H1

1.59e-06151124PF03028
DomainDynein_heavy_dom

DYNC2H1 DNAH12 DNAH8 DYNC1H1

1.59e-06151124IPR004273
DomainGOLGA2L5

GOLGA6L4 GOLGA6L10 GOLGA6L19 GOLGA6L9

3.51e-06181124PF15070
DomainGolgin_A

GOLGA6L4 GOLGA6L10 GOLGA6L19 GOLGA6L9

3.51e-06181124IPR024858
DomainDHC_N1

DYNC2H1 DNAH8 DYNC1H1

1.15e-0581123PF08385
DomainDynein_heavy_dom-1

DYNC2H1 DNAH8 DYNC1H1

1.15e-0581123IPR013594
DomainDUF1712

CCZ1B CCZ1

3.56e-0521122PF08217
DomainDUF1712_fun

CCZ1B CCZ1

3.56e-0521122IPR013176
DomainDynein_HC_stalk

DYNC2H1 DNAH8 DYNC1H1

7.28e-05141123IPR024743
DomainMT

DYNC2H1 DNAH8 DYNC1H1

7.28e-05141123PF12777
DomainVDCC_L_a1su

CACNA1F CACNA1S

2.12e-0441122IPR005446
DomainAAA

ABCF3 DYNC2H1 WRNIP1 DNAH12 DNAH8 DYNC1H1

2.31e-041441126SM00382
DomainAAA+_ATPase

ABCF3 DYNC2H1 WRNIP1 DNAH12 DNAH8 DYNC1H1

2.31e-041441126IPR003593
DomainVal/Leu/Ile-tRNA-synth_edit

LARS1 LARS2

5.26e-0461122IPR009008
DomainAnticodon_1

LARS1 LARS2

5.26e-0461122PF08264
DomainM/V/L/I-tRNA-synth_anticd-bd

LARS1 LARS2

5.26e-0461122IPR013155
Domain-

LARS1 LARS2

5.26e-04611223.90.740.10
DomainHECT

HUWE1 HERC1 SMURF2

5.53e-04271123PF00632
DomainHECTc

HUWE1 HERC1 SMURF2

5.53e-04271123SM00119
DomainHECT_dom

HUWE1 HERC1 SMURF2

5.53e-04271123IPR000569
DomainHECT

HUWE1 HERC1 SMURF2

5.53e-04271123PS50237
DomainIon_trans_dom

CACNA1F CACNA1S TRPC7 CATSPER1 TRPV3

6.19e-041141125IPR005821
DomainIon_trans

CACNA1F CACNA1S TRPC7 CATSPER1 TRPV3

6.19e-041141125PF00520
Domainaa-tRNA-synth_Ia

LARS1 LARS2

7.34e-0471122IPR002300
DomaintRNA-synt_1

LARS1 LARS2

7.34e-0471122PF00133
DomainCa_chan_IQ

CACNA1F CACNA1S

7.34e-0471122SM01062
DomainCa_chan_IQ

CACNA1F CACNA1S

7.34e-0471122PF08763
DomainVDCC_a1su_IQ

CACNA1F CACNA1S

7.34e-0471122IPR014873
DomainGPHH

CACNA1F CACNA1S

7.34e-0471122PF16905
DomainGPHH_dom

CACNA1F CACNA1S

7.34e-0471122IPR031649
DomainDNA/RNA_helicase_DEAH_CS

DHX38 CHD2 CHD6

1.19e-03351123IPR002464
DomainDEAH_ATP_HELICASE

DHX38 CHD2 CHD6

1.52e-03381123PS00690
DomainVDCCAlpha1

CACNA1F CACNA1S

1.55e-03101122IPR002077
DomainCENP-B_N

TIGD5 JRKL

1.55e-03101122PF04218
Domain-

LARS1 LARS2

1.89e-031111221.10.730.10
DomainHTH_Psq

TIGD5 JRKL

2.26e-03121122IPR007889
DomainHTH_PSQ

TIGD5 JRKL

2.26e-03121122PS50960
DomainCENPB

TIGD5 JRKL

2.26e-03121122SM00674
DomainPeptidase_M1

RNPEPL1 ERAP2

2.26e-03121122IPR001930
DomainDDE_1

TIGD5 JRKL

2.26e-03121122PF03184
DomainDDE_SF_endonuclease_dom

TIGD5 JRKL

2.26e-03121122IPR004875
DomainHTH_CENPB

TIGD5 JRKL

2.66e-03131122PS51253
DomainHTH_Tnp_Tc5

TIGD5 JRKL

2.66e-03131122PF03221
DomainPeptidase_M1_N

RNPEPL1 ERAP2

2.66e-03131122IPR014782
DomainPeptidase_M1

RNPEPL1 ERAP2

2.66e-03131122PF01433
DomainHTH_CenpB_DNA-bd_dom

TIGD5 JRKL

2.66e-03131122IPR006600
DomainRas_G-nucl-exch_fac_CS

RAPGEF4 RAPGEF3

3.09e-03141122IPR019804
DomaintRNAsynth_Ia_anticodon-bd

LARS1 LARS2

3.56e-03151122IPR009080
DomainARM-type_fold

DOCK1 TRPC4AP IPO8 RNPEPL1 RTTN HUWE1 CUL7

4.35e-033391127IPR016024
DomainChannel_four-helix_dom

CACNA1F CACNA1S CATSPER1

4.85e-03571123IPR027359
Domain-

CACNA1F CACNA1S CATSPER1

4.85e-035711231.20.120.350
DomainP-loop_NTPase

KIF21B ABCF3 DYNC2H1 DHX38 WRNIP1 CHD2 MYO3A DNAH12 CHD6 KIF13A DNAH8 DYNC1H1

4.88e-0384811212IPR027417
Domainaa-tRNA-synth_I_CS

LARS1 LARS2

5.12e-03181122IPR001412
DomainAA_TRNA_LIGASE_I

LARS1 LARS2

5.70e-03191122PS00178
Pubmed

Identification of dynein heavy chain genes expressed in human and mouse testis: chromosomal localization of an axonemal dynein gene.

DYNC2H1 DNAH12 DNAH17 DNAH8 DYNC1H1

6.77e-101411459373155
Pubmed

Mammalian cells express three distinct dynein heavy chains that are localized to different cytoplasmic organelles.

DYNC2H1 DNAH12 DYNC1H1

3.43e-08311438666668
Pubmed

Construction of long-transcript enriched cDNA libraries from submicrogram amounts of total RNAs by a universal PCR amplification method.

CLN8 CCZ1B TICRR ABCF3 ICA1 DHX38 OAS1 CHD2 HUWE1 ADGRE2 MESD ARID1B CCZ1 CTR9 PLEC HERC1 KIF13A

9.47e-0810841141711544199
Pubmed

Multiple mouse chromosomal loci for dynein-based motility.

DYNC2H1 DNAH12 PIM1 DNAH8 DYNC1H1

4.76e-074711458812413
Pubmed

Mouse screen reveals multiple new genes underlying mouse and human hearing loss.

SEL1L KIF21B SETD1A TRPC4AP LARS1 SLC5A7 OAS1 ARSG SMYD2 PPP2R2B ARID1B GLE1 CTR9 DNAH17 ZNF778 CFAP61 HERC1

6.36e-0712421141730973865
Pubmed

A dual-activity topoisomerase complex regulates mRNA translation and turnover.

SETD1A FRAS1 POLE INPPL1 RNPEPL1 RTTN AOC2 HUWE1 LARS2 SLC29A2 PLEKHM1 ARSG PLEC HERC1 SMURF2 DYNC1H1

6.75e-0711051141635748872
Pubmed

An antibody-based proximity labeling map reveals mechanisms of SARS-CoV-2 inhibition of antiviral immunity.

CCZ1B DNAJC16 ICA1 WRNIP1 FASTKD5 HUWE1 NDUFS1 STRIP1 TFRC MESD ARID1B GLE1 CHD6

8.96e-077331141334672954
Pubmed

Prediction of the coding sequences of mouse homologues of KIAA gene: IV. The complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.

ARHGEF28 SYNM DYNC2H1 DHX38 CUL7 BTBD9 SLITRK1 ARSG DNAH17 DOP1A

5.46e-064931141015368895
Pubmed

Mice depleted for Exchange Proteins Directly Activated by cAMP (Epac) exhibit irregular liver regeneration in response to partial hepatectomy.

RAPGEF4 RAPGEF3

1.07e-052114231551444
Pubmed

eNOSI4 and EPHX1 polymorphisms affect maternal susceptibility to preeclampsia: analysis of five polymorphisms predisposing to cardiovascular disease in 279 Caucasian and 241 African women.

EPHX1 NOS3

1.07e-052114224013430
Pubmed

EPAC Regulates Melanoma Growth by Stimulating mTORC1 Signaling and Loss of EPAC Signaling Dependence Correlates with Melanoma Progression.

RAPGEF4 RAPGEF3

1.07e-052114235834616
Pubmed

Exchange protein directly activated by cAMP (Epac) protects against airway inflammation and airway remodeling in asthmatic mice.

RAPGEF4 RAPGEF3

1.07e-052114231852500
Pubmed

Urinary concentrating defect in mice lacking Epac1 or Epac2.

RAPGEF4 RAPGEF3

1.07e-052114230252533
Pubmed

Genetic analysis of the cytoplasmic dynein subunit families.

DYNC2H1 DYNC1H1

1.07e-052114216440056
Pubmed

Exchange Protein Directly Activated by cAMP (EPAC) Regulates Neuronal Polarization through Rap1B.

RAPGEF4 RAPGEF3

1.07e-052114226269639
Pubmed

Inhibition of EPAC1 signaling pathway alters atrial electrophysiology and prevents atrial fibrillation.

RAPGEF4 RAPGEF3

1.07e-052114236909224
Pubmed

Possible role of the exchange protein directly activated by cyclic AMP (Epac) in the cyclic AMP-dependent functional differentiation and syncytialization of human placental BeWo cells.

RAPGEF4 RAPGEF3

1.07e-052114220663796
Pubmed

Biochemical characterization of the mouse ABCF3 protein, a partner of the flavivirus-resistance protein OAS1B.

ABCF3 OAS1

1.07e-052114231413116
Pubmed

Epac: new emerging cAMP-binding protein.

RAPGEF4 RAPGEF3

1.07e-052114233298248
Pubmed

Epac1 inhibition ameliorates pathological angiogenesis through coordinated activation of Notch and suppression of VEGF signaling.

RAPGEF4 RAPGEF3

1.07e-052114231911948
Pubmed

Epac1-deficient mice have bleeding phenotype and thrombocytes with decreased GPIbβ expression.

RAPGEF4 RAPGEF3

1.07e-052114228821815
Pubmed

β-Adrenergic Receptors/Epac Signaling Increases the Size of the Readily Releasable Pool of Synaptic Vesicles Required for Parallel Fiber LTP.

RAPGEF4 RAPGEF3

1.07e-052114233046543
Pubmed

Renal expression of exchange protein directly activated by cAMP (Epac) 1 and 2.

RAPGEF4 RAPGEF3

1.07e-052114218495799
Pubmed

Anxiety and depression with neurogenesis defects in exchange protein directly activated by cAMP 2-deficient mice are ameliorated by a selective serotonin reuptake inhibitor, Prozac.

RAPGEF4 RAPGEF3

1.07e-052114227598965
Pubmed

EPAC Negatively Regulates Myelination via Controlling Proliferation of Oligodendrocyte Precursor Cells.

RAPGEF4 RAPGEF3

1.07e-052114232303914
Pubmed

B cell receptor-induced growth arrest and apoptosis in WEHI-231 immature B lymphoma cells involve cyclic AMP and Epac proteins.

RAPGEF4 RAPGEF3

1.07e-052114219167486
Pubmed

Exchange Proteins Directly Activated by cAMP and Their Roles in Respiratory Syncytial Virus Infection.

RAPGEF4 RAPGEF3

1.07e-052114230185593
Pubmed

Epac Signaling Is Required for Cocaine-Induced Change in AMPA Receptor Subunit Composition in the Ventral Tegmental Area.

RAPGEF4 RAPGEF3

1.07e-052114227122037
Pubmed

Epac1-/- and Epac2-/- mice exhibit deficient epithelial Na+ channel regulation and impaired urinary Na+ conservation.

RAPGEF4 RAPGEF3

1.07e-052114234914636
Pubmed

Epac2-deficiency leads to more severe retinal swelling, glial reactivity and oxidative stress in transient middle cerebral artery occlusion induced ischemic retinopathy.

RAPGEF4 RAPGEF3

1.07e-052114225985753
Pubmed

The cAMP sensors, EPAC1 and EPAC2, display distinct subcellular distributions despite sharing a common nuclear pore localisation signal.

RAPGEF4 RAPGEF3

1.07e-052114225683912
Pubmed

Origin and Isoform Specific Functions of Exchange Proteins Directly Activated by cAMP: A Phylogenetic Analysis.

RAPGEF4 RAPGEF3

1.07e-052114234685730
Pubmed

Role of dynamics in the autoinhibition and activation of the exchange protein directly activated by cyclic AMP (EPAC).

RAPGEF4 RAPGEF3

1.07e-052114221873431
Pubmed

Inhibition of microtubules and dynein rescues human immunodeficiency virus type 1 from owl monkey TRIMCyp-mediated restriction in a cellular context-specific fashion.

DYNC2H1 DYNC1H1

1.07e-052114225502651
Pubmed

Increased microvascular permeability in mice lacking Epac1 (Rapgef3).

RAPGEF4 RAPGEF3

1.07e-052114227096875
Pubmed

Deletion of exchange proteins directly activated by cAMP (Epac) causes defects in hippocampal signaling in female mice.

RAPGEF4 RAPGEF3

1.07e-052114230048476
Pubmed

Evidence for existence of cAMP-Epac signaling in the heads of mouse epididymal spermatozoa.

RAPGEF4 RAPGEF3

1.07e-052114217077580
Pubmed

The role of Epac in the heart.

RAPGEF4 RAPGEF3

1.07e-052114227549789
Pubmed

Insights into exchange factor directly activated by cAMP (EPAC) as potential target for cancer treatment.

RAPGEF4 RAPGEF3

1.07e-052114229417338
Pubmed

Structure and regulation of the cAMP-binding domains of Epac2.

RAPGEF4 RAPGEF3

1.07e-052114212469113
Pubmed

Prediction of the coding sequences of unidentified human genes. VII. The complete sequences of 100 new cDNA clones from brain which can code for large proteins in vitro.

SETD1A SYNM HUWE1 PLEKHM1 DYNC1H1

2.46e-0510411459205841
Pubmed

E3 ubiquitin ligase RNF123 targets lamin B1 and lamin-binding proteins.

CACNA1F TICRR ICA1 SLC5A7 DGKH CHD2 HUWE1 AGL PKHD1 CHD6 DYNC1H1

3.16e-057361141129676528
Pubmed

Exchange protein activated by cAMP (Epac) mediates cAMP activation of p38 MAPK and modulation of Ca2+-dependent K+ channels in cerebellar neurons.

RAPGEF4 RAPGEF3

3.19e-053114217284589
Pubmed

Dynein is required for receptor sorting and the morphogenesis of early endosomes.

TFRC DNAH12

3.19e-053114217173037
Pubmed

PI3KC3 complex subunit NRBF2 is required for apoptotic cell clearance to restrict intestinal inflammation.

CCZ1B CCZ1

3.19e-053114232160108
Pubmed

EPAC null mutation impairs learning and social interactions via aberrant regulation of miR-124 and Zif268 translation.

RAPGEF4 RAPGEF3

3.19e-053114222365550
Pubmed

Cytoplasmic dynein promotes HIV-1 uncoating.

DYNC2H1 DYNC1H1

3.19e-053114225375884
Pubmed

EPAC inhibition of SUR1 receptor increases glutamate release and seizure vulnerability.

RAPGEF4 RAPGEF3

3.19e-053114223678128
Pubmed

Anti-inflammatory role of the cAMP effectors Epac and PKA: implications in chronic obstructive pulmonary disease.

RAPGEF4 RAPGEF3

3.19e-053114222363678
Pubmed

Exchange protein directly activated by cAMP (EPAC) interacts with the light chain (LC) 2 of MAP1A.

RAPGEF4 RAPGEF3

3.19e-053114215202935
Pubmed

The Epac-Phospholipase Cε Pathway Regulates Endocannabinoid Signaling and Cocaine-Induced Disinhibition of Ventral Tegmental Area Dopamine Neurons.

RAPGEF4 RAPGEF3

3.19e-053114228209735
Pubmed

Epac1-dependent phospholamban phosphorylation mediates the cardiac response to stresses.

RAPGEF4 RAPGEF3

3.19e-053114224892712
Pubmed

Recombinant human cytoplasmic dynein heavy chain 1 and 2: observation of dynein-2 motor activity in vitro.

DYNC2H1 DYNC1H1

3.19e-053114221723285
Pubmed

Deficiency of the purine metabolic gene HPRT dysregulates microRNA-17 family cluster and guanine-based cellular functions: a role for EPAC in Lesch-Nyhan syndrome.

RAPGEF4 RAPGEF3

3.19e-053114223804752
Pubmed

A family of cAMP-binding proteins that directly activate Rap1.

RAPGEF4 RAPGEF3

3.19e-05311429856955
Pubmed

Pim1 kinase promotes angiogenesis through phosphorylation of endothelial nitric oxide synthase at Ser-633.

PIM1 NOS3

3.19e-053114226598507
Pubmed

Epac1 and Epac2 are differentially involved in inflammatory and remodeling processes induced by cigarette smoke.

RAPGEF4 RAPGEF3

3.19e-053114225103224
Pubmed

Liver receptor homolog 1 is essential for ovulation.

AMHR2 NOS3

3.19e-053114218628394
Pubmed

Genomic Alterations of NTRK, POLE, ERBB2, and Microsatellite Instability Status in Chinese Patients with Colorectal Cancer.

POLE SLITRK1

3.19e-053114232627883
Pubmed

Identification of novel host cell binding partners of Oas1b, the protein conferring resistance to flavivirus-induced disease in mice.

ABCF3 OAS1

3.19e-053114222623793
Pubmed

Usefulness of Exchanged Protein Directly Activated by cAMP (Epac)1-Inhibiting Therapy for Prevention of Atrial and Ventricular Arrhythmias in Mice.

RAPGEF4 RAPGEF3

3.19e-053114230518738
Pubmed

Analysis of the DNA sequence and duplication history of human chromosome 15.

CHD2 GOLGA6L4 GOLGA6L10 GOLGA6L19

3.53e-0556114416572171
Pubmed

Genome-wide association study of a heart failure related metabolomic profile among African Americans in the Atherosclerosis Risk in Communities (ARIC) study.

ICA1 DGKH EYS SLC12A1

3.53e-0556114423934736
Pubmed

Kelch Domain of Gigaxonin Interacts with Intermediate Filament Proteins Affected in Giant Axonal Neuropathy.

KIF21B DYNC2H1 RTTN GAN PLEC DNAH8

3.67e-05187114626460568
Pubmed

A CRISPR-based screen for Hedgehog signaling provides insights into ciliary function and ciliopathies.

EPHX1 DLGAP2 TEDC2 CHD2 TFRC PLEC DYNC1H1

4.39e-05284114729459677
Pubmed

A trimeric Rab7 GEF controls NPC1-dependent lysosomal cholesterol export.

SEL1L EPHX1 DNAJC16 APMAP LARS1 HUWE1 CCZ1 DYNC1H1

4.72e-05392114833144569
Pubmed

The Hsp70-Hsp90 co-chaperone Hop/Stip1 shifts the proteostatic balance from folding towards degradation.

IPO8 DNAJC16 LARS1 WRNIP1 HUWE1 NDUFS1 TFRC CTR9 PLEC DYNC1H1

4.95e-056381141033239621
Pubmed

TNF-α inhibits glucocorticoid receptor-induced gene expression by reshaping the GR nuclear cofactor profile.

TRPC4AP DYNC2H1 POLE CHD2 NDUFS1 PPP2R2B ARID1B DNAH12 CHD6 TIGD5

4.95e-056381141031182584
Pubmed

A novel membrane protein is a mouse mammary tumor virus receptor.

FAM89B TFRC

6.36e-05411429525630
Pubmed

CalDAG-GEFI integrates signaling for platelet aggregation and thrombus formation.

RAPGEF4 RAPGEF3

6.36e-054114215334074
Pubmed

Beta-adrenergic-regulated phosphorylation of the skeletal muscle Ca(V)1.1 channel in the fight-or-flight response.

CACNA1F CACNA1S

6.36e-054114220937870
Pubmed

Interaction of ATP sensor, cAMP sensor, Ca2+ sensor, and voltage-dependent Ca2+ channel in insulin granule exocytosis.

CACNA1S RAPGEF4

6.36e-054114214660679
Pubmed

cAMP-Epac2-mediated activation of Rap1 in developing male germ cells: RA-RhoGAP as a possible direct down-stream effector.

RAPGEF4 RAPGEF3

6.36e-054114218937323
Pubmed

An axonemal dynein at the Hybrid Sterility 6 locus: implications for t haplotype-specific male sterility and the evolution of species barriers.

PIM1 DNAH8

6.36e-054114210602986
Pubmed

Regulation of mitochondrial morphology and function by stearoylation of TFR1.

HUWE1 TFRC

6.36e-054114226214738
Pubmed

Binding of microtubule-associated protein 1B to LIS1 affects the interaction between dynein and LIS1.

DNAH8 DYNC1H1

6.36e-054114215762842
Pubmed

Identification of two evolutionarily conserved genes regulating processing of engulfed apoptotic cells.

CCZ1B CCZ1

6.36e-054114220305638
Pubmed

Slowed conduction and thin myelination of peripheral nerves associated with mutant rho Guanine-nucleotide exchange factor 10.

CLN8 DLGAP2

6.36e-054114214508709
Pubmed

Identification of Zika Virus and Dengue Virus Dependency Factors using Functional Genomics.

EPHX1 LARS1 HUWE1 NDUFS1 TFRC CTR9 AGL DYNC1H1

7.89e-05422114827342126
Pubmed

A high-throughput approach for measuring temporal changes in the interactome.

CACNA1S ABCF3 INPPL1 DHX38 LARS1 WRNIP1 UBA3 HUWE1 CTR9 AGL GNPDA2 PLEC HERC1 KIF13A DYNC1H1

8.36e-0514551141522863883
Pubmed

System-Wide Modulation of HECT E3 Ligases with Selective Ubiquitin Variant Probes.

HUWE1 HERC1 SMURF2

8.44e-0526114326949039
Pubmed

Proteome-scale mapping of binding sites in the unstructured regions of the human proteome.

DOCK1 SETD1A CACNA1S DLGAP2 INPPL1 SLC12A1 PLEC DYNC1H1

8.99e-05430114835044719
Pubmed

A Rap guanine nucleotide exchange factor enriched highly in the basal ganglia.

RAPGEF4 RAPGEF3

1.06e-04511429789079
Pubmed

Mechanism of regulation of the Epac family of cAMP-dependent RapGEFs.

RAPGEF4 RAPGEF3

1.06e-045114210777494
Pubmed

Activation of EPAC1/2 is essential for osteoclast formation by modulating NFκB nuclear translocation and actin cytoskeleton rearrangements.

RAPGEF4 RAPGEF3

1.06e-045114225122553
Pubmed

NEDD4-family E3 ligase dysfunction due to PKHD1/Pkhd1 defects suggests a mechanistic model for ARPKD pathobiology.

PKHD1 SMURF2

1.06e-045114228798345
Pubmed

Epac2 mediates cardiac β1-adrenergic-dependent sarcoplasmic reticulum Ca2+ leak and arrhythmia.

RAPGEF4 RAPGEF3

1.06e-045114223363625
Pubmed

Neuronal AKAP150 coordinates PKA and Epac-mediated PKB/Akt phosphorylation.

RAPGEF4 RAPGEF3

1.06e-045114218565730
Pubmed

Direct interaction between hnRNP-M and CDC5L/PLRG1 proteins affects alternative splice site choice.

DOCK1 CCZ1B ABCF3 POLE WRNIP1 HUWE1 CCZ1 PLEC DYNC1H1

1.32e-04582114920467437
Pubmed

Functional proteomics mapping of a human signaling pathway.

HUWE1 ARID1B CTR9 CHD6 PLEC HERC1 KIF13A SMURF2 DYNC1H1

1.48e-04591114915231748
Pubmed

Developmental changes in gene expression of Epac and its upregulation in myocardial hypertrophy.

RAPGEF4 RAPGEF3

1.58e-046114217557924
Pubmed

β-Sheet Augmentation Is a Conserved Mechanism of Priming HECT E3 Ligases for Ubiquitin Ligation.

HUWE1 SMURF2

1.58e-046114229964046
Pubmed

Ras and relatives--job sharing and networking keep an old family together.

RAPGEF4 RAPGEF3

1.58e-046114212384139
Pubmed

Novel Rap1 dominant-negative mutants interfere selectively with C3G and Epac.

RAPGEF4 RAPGEF3

1.58e-046114215856025
Pubmed

A quantitative analysis of the spatiotemporal pattern of transient receptor potential gene expression in the developing mouse cochlea.

TRPC7 PKD1L2 TRPV3

1.74e-0433114319834762
Pubmed

MKRN2 Physically Interacts with GLE1 to Regulate mRNA Export and Zebrafish Retinal Development.

CNOT11 DYNC2H1 LARS1 WRNIP1 HUWE1 GLE1 DYNC1H1

1.85e-04358114732460013
Pubmed

Isolation of several human axonemal dynein heavy chain genes: genomic structure of the catalytic site, phylogenetic analysis and chromosomal assignment.

DNAH12 DNAH8

2.21e-04711429256245
Pubmed

Enhanced expression of L-type Cav1.3 calcium channels in murine embryonic hearts from Cav1.2-deficient mice.

CACNA1F CACNA1S

2.21e-047114212900400
Pubmed

Synemin promotes AKT-dependent glioblastoma cell proliferation by antagonizing PP2A.

SYNM PPP2R2B

2.21e-047114222337773
Pubmed

Multiple roles of Rap1 in hematopoietic cells: complementary versus antagonistic functions.

RAPGEF4 RAPGEF3

2.21e-047114216076873
Cytoband15q25.2

GOLGA6L4 GOLGA6L10 WDR73 GOLGA6L9

3.99e-0643113415q25.2
CytobandEnsembl 112 genes in cytogenetic band chr15q25

GOLGA6L4 GOLGA6L10 MESD WDR73 GOLGA6L9

5.00e-051601135chr15q25
Cytoband8p23

CLN8 DLGAP2

5.36e-041411328p23
GeneFamilyDyneins, axonemal

DNAH12 DNAH17 DNAH8

4.12e-0517733536
GeneFamilyDyneins, cytoplasmic

DYNC2H1 DYNC1H1

1.22e-0313732538
GeneFamilyHelix-turn-helix CENPB type domain containing

TIGD5 JRKL

1.22e-0313732533
GeneFamilyEndogenous ligands|C1q and TNF related

C1QTNF4 C1QTNF6

2.36e-03187321372
GeneFamilyAminoacyl tRNA synthetases, Class I

LARS1 LARS2

2.63e-0319732131
GeneFamilyZinc fingers MYND-type

DEAF1 SMYD2

3.21e-032173287
GeneFamilyCalcium voltage-gated channel subunits

CACNA1F CACNA1S

4.91e-0326732253
GeneFamilyTransient receptor potential cation channels

TRPC7 TRPV3

5.68e-0328732249
ToppCell10x5'-GI_small-bowel-Lymphocytic_T_CD4-T_CD4/CD8|GI_small-bowel / Manually curated celltypes from each tissue

DGKH CHD2 HUWE1 BTBD9 ARID1B HERC1 DYNC1H1

5.61e-071881147ab9b725d6e0cdab8e9ddda6dee09e14730e9a578
ToppCellCOVID-CD8-memory_CD4|COVID / Condition, Cell_class and T cell subcluster

SYNM DYNC2H1 LARS1 GLE1 C1QTNF6 DOP1A

3.84e-06162114622b2a32217d357146c117e618813d451510a1801
ToppCell10x5'-Liver-Lymphocytic_T_CD4-T_CD4/CD8|Liver / Manually curated celltypes from each tissue

DGKH CHD2 HUWE1 TFRC ARID1B HERC1

7.26e-061811146f2315414e714ac86211546a935660c4be6e85f1b
ToppCell343B-Lymphocytic-CD8+_Cytotoxic_T-cell-CD8+_Cytotoxic_T_cell_0.5|CD8+_Cytotoxic_T-cell / Donor, Lineage, Cell class and subclass (all cells)

OAS1 FASTKD5 GOLGA6L10 PPP2R2B PLEC GOLGA6L9

8.48e-061861146bbb8edea8d8bdc1a469faec1563e40b1f62d7f3d
ToppCellTCGA-Prostate-Primary_Tumor-Prostate_Adenocarcinoma-Acinar_Adenocarcinoma-6|TCGA-Prostate / Sample_Type by Project: Shred V9

DNAJC16 HUWE1 NDUFS1 CTR9 USP32 DYNC1H1

1.05e-051931146abd71b2cf667ef2b1c4d88acd0c1dd19a12ff659
ToppCellTracheal-NucSeq|Tracheal / Cell types per location group and 10X technology with lineage, and cell group designations

DOCK1 ARHGEF28 BTBD9 CHRM3 ARID1B HERC1

1.25e-05199114694b94b17ca18b8dc27b91da1f2ccf89e03cc7035
DiseaseTimothy syndrome (implicated_via_orthology)

CACNA1F CACNA1S

7.78e-0541072DOID:0060173 (implicated_via_orthology)
DiseaseGilles de la Tourette syndrome

CHD2 SLITRK1

7.78e-0541072C0040517
Diseasecongenital stationary night blindness (is_implicated_in)

CACNA1F TRPV3

7.78e-0541072DOID:0050534 (is_implicated_in)
Diseaseresponse to platinum based chemotherapy, cytotoxicity measurement

FRAS1 EYS

1.29e-0451072EFO_0004647, EFO_0006952
DiseaseChronic Obstructive Airway Disease

EPHX1 RAPGEF3 NOS3

2.34e-04331073C0024117
DiseaseChronic Airflow Obstruction

EPHX1 RAPGEF3 NOS3

2.34e-04331073C1527303
DiseaseCHARGE syndrome (implicated_via_orthology)

CHD2 CHD6

2.70e-0471072DOID:0050834 (implicated_via_orthology)
Diseaseinformation processing speed, cognitive function measurement

CLN8 DLGAP2

5.75e-04101072EFO_0004363, EFO_0008354
DiseaseR-6-hydroxywarfarin to R-warfarin ratio measurement

EYS TAS2R14 DNAH17 GAN

6.11e-041061074EFO_0803333
Diseaseabdominal adipose tissue measurement

CACNA1S FASTKD5 PKHD1

9.52e-04531073EFO_0803316
Diseaseblood nickel measurement

DLGAP2 EYS SLC12A1 KIF13A

9.72e-041201074EFO_0007583
DiseaseHermansky-Pudlak syndrome (implicated_via_orthology)

CCZ1B CCZ1

1.15e-03141072DOID:3753 (implicated_via_orthology)
Diseasecardiac troponin T measurement

CACNA1S DLGAP2 PKD1L2 PKHD1 KIF13A

1.24e-032191075EFO_0005043
DiseasePre-Eclampsia

EPHX1 NOS3

1.51e-03161072C0032914
Diseaseforced expiratory volume

SETD1A IPO8 LARS2 CHRM3 PLEKHM1 EYS DNAH12 GPC3 AGL

2.33e-037891079EFO_0004314
Diseasefumarate measurement

LARS2 EYS

2.62e-03211072EFO_0010480
DiseaseLymphoma, Diffuse

EPHX1 TFRC

2.62e-03211072C3714542
DiseaseLow Grade Lymphoma (neoplasm)

EPHX1 TFRC

2.62e-03211072C0079747
DiseaseLymphoma, Intermediate-Grade

EPHX1 TFRC

2.62e-03211072C0079741
DiseaseHigh Grade Lymphoma (neoplasm)

EPHX1 TFRC

2.62e-03211072C0079740
DiseaseDiffuse Mixed-Cell Lymphoma

EPHX1 TFRC

2.62e-03211072C0079757
DiseaseLymphoma, Undifferentiated

EPHX1 TFRC

2.62e-03211072C0024306
DiseaseReticulosarcoma

EPHX1 TFRC

2.62e-03211072C0024302
DiseaseLymphoma, Mixed-Cell

EPHX1 TFRC

2.62e-03211072C0024304
DiseaseMetabolic Syndrome X

INPPL1 NOS3

2.62e-03211072C0524620
DiseaseLymphoma, Non-Hodgkin, Familial

EPHX1 TFRC

2.87e-03221072C4721532
DiseaseLymphoma, Small Noncleaved-Cell

EPHX1 TFRC

2.87e-03221072C0079770
DiseaseMyasthenic Syndromes, Congenital

SLC5A7 PLEC

3.41e-03241072C0751882
Diseasebody fat percentage, coronary artery disease

DYNC2H1 DGKH

3.41e-03241072EFO_0001645, EFO_0007800

Protein segments in the cluster

PeptideGeneStartEntry
ETYMSADDLRINLWN

PPP2R2B

186

Q00005
TMYRDAILAQWNDGL

CFAP61

896

Q8NHU2
LLTLDDWSLIYMDSR

CATSPER1

626

Q8NEC5
WMLLEALYLFLTARN

ADGRE2

616

Q9UHX3
NMLDVRAILWLENYL

ABCF3

356

Q9NUQ8
TTYIIMNRWALGNLA

CHRM3

126

P20309
SAMLQLDYGDTVWLR

C1QTNF4

121

Q9BXJ3
RSLYGAGLWEMDSLV

ARSG

266

Q96EG1
SQDLAGYWDMLQLSI

DLGAP2

941

Q9P1A6
DMSLNRRLYAWLLGF

DOP1A

281

Q5JWR5
SGMIRLYAAIIQLRW

GLE1

571

Q53GS7
LWGSHLLSREEAAYM

ADCK5

441

Q3MIX3
LWVDRYLTFMEERGS

ARID1B

1141

Q8NFD5
WQRRDYLLLVMEGTD

APMAP

221

Q9HDC9
WGMALRRADIYSLAL

AMHR2

401

Q16671
MSEERTLLYDGLVYW

ARHGEF28

1081

Q8N1W1
DMERALSWGRYQLVV

AOC2

616

O75106
MDNFDYLTRDWSILG

CACNA1F

1441

O60840
RIVTNLGLQWLEYMD

FRAS1

2441

Q86XX4
LRWAGNMYLENTTDD

EYS

556

Q5T1H1
WREYILSLEELVNGM

GPC3

296

P51654
RAIFMLRDGSYAWEI

MESD

156

Q14696
AQRGSLRYLLEWIEM

HERC1

256

Q15751
LRYLLEWIEMALGAS

HERC1

261

Q15751
RWAFMLAILSIGDAL

LHFPL5

176

Q8TAF8
RQLDMSLLCQLWGLY

FAM89B

101

Q8N5H3
YMADRLLGVVSSWLE

CUL7

1271

Q14999
YIFNLRDLSRIWQGM

DNAH8

2656

Q96JB1
LSWTLAMAIFYGINR

DNAH8

3271

Q96JB1
MLYAASGNAVRIWEL

KIF21B

1426

O75037
WMERLLEGSLQRFYI

DNAJC16

761

Q9Y2G8
DWDRRLLLTMLADFY

DNAH12

2716

Q6ZR08
LERMLELGWEALYEQ

GOLGA6L3

426

A6NEY3
LERMLELGWEALYEQ

GOLGA6L4

451

A6NEF3
RMLELGWEALYEQRA

GOLGA6L9

311

A6NEM1
RMLELGWEALYEQRA

GOLGA6L10

401

A6NI86
ELERMLELGWEALYE

GOLGA6L19

426

H0YKK7
LGAVELSWDYMQSDL

F8

26

P00451
DQRIRWYLLSMGSNE

F8

1956

P00451
TLLDALYEIAMAWNL

JRKL

361

Q9Y4A0
GMSYLLETLEWLLQK

POLE

2266

Q07864
WLYLTAETLKNRMGR

NPIPB7

231

O75200
ALELLTVYAWERGSM

OAS1

231

P00973
MWYGVLGTRELLQRS

DGKH

806

Q86XP1
QDAGGLLREWYMIIS

HUWE1

4056

Q7Z6Z7
ALIREILAYLGFLWM

PKD1L2

1946

Q7Z442
LGLRWYALPAVSNML

NOS3

326

P29474
YQLLGHIDMDTREWS

DYNC2H1

2016

Q8NCM8
MDQLLLVADLWRYLG

FASTKD5

241

Q7L8L6
GSELLWYLAEKDMNS

FASTKD5

541

Q7L8L6
LDDLLTNVMLYWTTG

EPHX1

351

P07099
SQSVMLDLAYGDRVW

C1QTNF6

231

Q9BXI9
MIYDLIEWRSQILSG

DOCK1

121

Q14185
MGLAAWYADLLLRIR

DNAH17

4291

Q9UFH2
MDNFDYLTRDWSILG

CACNA1S

1381

Q13698
GDLMSRNTIREYEWI

CHD2

566

O14647
LREYQLEGMNWLLFN

CHD6

461

Q8TD26
RSWLYLEEMVNSLLN

DEAF1

451

O75398
LWVSGLDSSYLREQM

GAN

221

Q9H2C0
LIWSGLEQDDMRILY

CCZ1

231

P86791
TYSMLALGNVWLQTL

CTR9

601

Q6PD62
LIWSGLEQDDMRILY

CCZ1B

231

P86790
WEYMLLGTDKSQLSL

DRC7

371

Q8IY82
MRLVILDNYDLASEW

GNPDA2

1

Q8TDQ7
MENWGLITYRETSLL

ERAP2

336

Q6P179
YAILWSLSGDSRLKM

DYNC1H1

2496

Q14204
YMWLQSRDLLAGLPA

LCAT

316

P04180
NLDMGYWESLLQQLR

CACTIN

431

Q8WUQ7
AQPYMIGSIRLLLWD

BTBD9

476

Q96Q07
WLYLTAETLKNRMGR

NPIPB9

246

F8W1W9
YRGALLWMKDVSQEL

ICA1

166

Q05084
RDAAWYQLLMAPLSE

IPO8

971

O15397
MWISILELNELGEYA

KIF13A

991

Q9H1H9
RSAAVWSLGILLYDM

PIM1

221

P11309
WLRLALNDGLMECYL

PLEKHM1

121

Q9Y4G2
YLLQGRLMMTALTWN

RTTN

696

Q86VV8
EVYSWLDSFLLLMLG

SLC5A7

236

Q9GZV3
SLSVLLWLRYMFKDG

TAS2R14

291

Q9NYV8
EMWLSEGLATYAQRR

RNPEPL1

371

Q9HAU8
RVIRLVLQWAAMYGD

RAPGEF4

576

Q8WZA2
DYMGEEQLRARSAWL

TNNT1

196

P13805
NVINWSLAAYGLIMR

SIDT2

696

Q8NBJ9
LFNIMDWLGRSLTSY

SLC29A2

336

Q14542
YTWLDNALVLDALMR

TRPC4AP

326

Q8TEL6
ATLTLAMADWLRDYQ

SYNM

281

O15061
MASVWQRLGFYASLL

LARS2

1

Q15031
DQLLGPEWDLYLMTI

SEL1L

736

Q9UBV2
DWMQEYRCLLTLEGL

TEDC2

291

Q7L2K0
YTSWEDALSRVAGML

NDUFS1

316

P28331
VEAMADAGILRLYTW

LARS1

756

Q9P2J5
QSWMRYNIFLLLEVG

STRIP1

166

Q5VSL9
MSAWLRAIGLERYEE

INPPL1

1201

O15357
EGTRDYEWLEALLMN

ST6GALNAC1

446

Q9NSC7
RKGSISDLLYMAWLE

SLC12A1

1061

Q13621
RGWMALLLDQETYSL

PKHD1

2611

P08F94
DIKEMGLSLQWLYSA

TFRC

631

P02786
WNSGLDSEDMSYLRL

SETD1A

1431

O15047
LDYASWGIRSTLMVA

CLN8

16

Q9UBY8
WMSRGLNTSILLQYL

CLCN2

121

P51788
AAQRLTALYLLWEMY

CNOT11

121

Q9UKZ1
GVAREWLYLLSHEML

SMURF2

436

Q9HAU4
ARRWINGMLISLLNY

UBA3

171

Q8TBC4
LRLVSQWVALYGSML

RAPGEF3

466

O95398
MLENYQNLVWLGLSI

ZNF542P

1

Q5EBM4
HGALMETLLDYQWDR

TICRR

101

Q7Z2Z1
MLENYENLASVEWRL

ZNF778

71

Q96MU6
NLLDLRWLYMDSNYL

SLITRK1

421

Q96PX8
LNSMYQLWILGALDN

DHX38

921

Q92620
LLLWSQRMVEGYQGL

PLEC

301

Q15149
RGSDQNASLYWLARM

WRNIP1

511

Q96S55
NASLYWLARMLEGGE

WRNIP1

516

Q96S55
YDMILLRSGNWELET

TRPV3

321

Q8NET8
DMLYLAGLSWDLVQA

TIGD5

456

Q53EQ6
LYSLNVASMWLKLGR

SMYD2

376

Q9NRG4
MRLWLYNSENYLTLL

USP32

666

Q8NFA0
MDPGDDWLVESLRLY

WDR73

1

Q6P4I2
QLLTMWYENLSGLRQ

TRPC7

331

Q9HCX4
DVMLENYRNLVWLGL

ZNF527

41

Q8NB42
RSGDWMIDYVSNRLI

AGL

961

P35573
DAMAKTLYGRLFSWI

MYO3A

676

Q8NEV4