Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyBiologicalProcess	actin filament capping	SPTBN4 SPTBN5 CRACD SPTB	5.85e-06	46	53	4	GO:0051693
GeneOntologyBiologicalProcess	regulation of protein depolymerization	SPTBN4 SPTBN5 CRACD NES SPTB	7.34e-06	105	53	5	GO:1901879
GeneOntologyBiologicalProcess	negative regulation of actin filament depolymerization	SPTBN4 SPTBN5 CRACD SPTB	9.60e-06	52	53	4	GO:0030835
GeneOntologyBiologicalProcess	regulation of actin filament depolymerization	SPTBN4 SPTBN5 CRACD SPTB	1.82e-05	61	53	4	GO:0030834
GeneOntologyBiologicalProcess	actin filament depolymerization	SPTBN4 SPTBN5 CRACD SPTB	2.49e-05	66	53	4	GO:0030042
GeneOntologyBiologicalProcess	protein depolymerization	SPTBN4 SPTBN5 CRACD NES SPTB	3.39e-05	144	53	5	GO:0051261
GeneOntologyBiologicalProcess	regulation of protein-containing complex disassembly	SPTBN4 SPTBN5 CRACD NES SPTB	3.39e-05	144	53	5	GO:0043244
GeneOntologyBiologicalProcess	regulation of phospholipid efflux	ABCA3 APOE	3.87e-05	4	53	2	GO:1902994
GeneOntologyBiologicalProcess	positive regulation of phospholipid efflux	ABCA3 APOE	3.87e-05	4	53	2	GO:1902995
GeneOntologyBiologicalProcess	negative regulation of actin filament polymerization	SPTBN4 SPTBN5 CRACD SPTB	4.13e-05	75	53	4	GO:0030837
GeneOntologyBiologicalProcess	negative regulation of protein depolymerization	SPTBN4 SPTBN5 CRACD SPTB	8.07e-05	89	53	4	GO:1901880
GeneOntologyBiologicalProcess	negative regulation of protein polymerization	SPTBN4 SPTBN5 CRACD SPTB	8.80e-05	91	53	4	GO:0032272
GeneOntologyBiologicalProcess	negative regulation of protein-containing complex disassembly	SPTBN4 SPTBN5 CRACD SPTB	1.27e-04	100	53	4	GO:0043242
GeneOntologyBiologicalProcess	negative regulation of supramolecular fiber organization	SPTBN4 SPTBN5 CRACD SPTB APOE	1.49e-04	197	53	5	GO:1902904
GeneOntologyCellularComponent	spectrin	SPTBN4 SPTBN5 SPTB	1.28e-06	9	53	3	GO:0008091
Domain	Actinin_actin-bd_CS	SPTBN4 SPTBN5 DST SPTB SYNE2	4.02e-09	23	51	5	IPR001589
Domain	Spectrin	SPTBN4 SPTBN5 DST SPTB SYNE2	4.02e-09	23	51	5	PF00435
Domain	ACTININ_2	SPTBN4 SPTBN5 DST SPTB SYNE2	4.02e-09	23	51	5	PS00020
Domain	ACTININ_1	SPTBN4 SPTBN5 DST SPTB SYNE2	4.02e-09	23	51	5	PS00019
Domain	Spectrin_repeat	SPTBN4 SPTBN5 DST SPTB SYNE2	1.40e-08	29	51	5	IPR002017
Domain	Spectrin/alpha-actinin	SPTBN4 SPTBN5 DST SPTB SYNE2	2.36e-08	32	51	5	IPR018159
Domain	SPEC	SPTBN4 SPTBN5 DST SPTB SYNE2	2.36e-08	32	51	5	SM00150
Domain	CH	SPTBN4 SPTBN5 DST SPTB SYNE2	9.06e-07	65	51	5	SM00033
Domain	CH	SPTBN4 SPTBN5 DST SPTB SYNE2	1.31e-06	70	51	5	PF00307
Domain	-	SPTBN4 SPTBN5 DST SPTB SYNE2	1.41e-06	71	51	5	1.10.418.10
Domain	CH	SPTBN4 SPTBN5 DST SPTB SYNE2	1.62e-06	73	51	5	PS50021
Domain	CH-domain	SPTBN4 SPTBN5 DST SPTB SYNE2	1.86e-06	75	51	5	IPR001715
Domain	Rhs_assc_core	TENM4 TENM3	2.19e-05	3	51	2	IPR022385
Domain	Tox-GHH_dom	TENM4 TENM3	4.37e-05	4	51	2	IPR028916
Domain	Ten_N	TENM4 TENM3	4.37e-05	4	51	2	IPR009471
Domain	Ten_N	TENM4 TENM3	4.37e-05	4	51	2	PF06484
Domain	TENEURIN_N	TENM4 TENM3	4.37e-05	4	51	2	PS51361
Domain	Spectrin_bsu	SPTBN4 SPTB	4.37e-05	4	51	2	IPR016343
Domain	Tox-GHH	TENM4 TENM3	4.37e-05	4	51	2	PF15636
Domain	YD	TENM4 TENM3	7.27e-05	5	51	2	IPR006530
Domain	PH_dom-spectrin-type	SPTBN4 SPTBN5	2.60e-04	9	51	2	IPR001605
Domain	NHL	TENM4 TENM3	5.59e-04	13	51	2	PS51125
Domain	CarboxyPept-like_regulatory	TENM4 TENM3	9.68e-04	17	51	2	IPR008969
Domain	Bromodomain_CS	BAZ2B BRPF1	2.28e-03	26	51	2	IPR018359
Domain	BROMODOMAIN_1	BAZ2B BRPF1	4.58e-03	37	51	2	PS00633
Domain	Bromodomain	BAZ2B BRPF1	4.83e-03	38	51	2	PF00439
Domain	-	TENM4 TENM3	5.08e-03	39	51	2	2.120.10.30
Domain	BROMODOMAIN_2	BAZ2B BRPF1	5.60e-03	41	51	2	PS50014
Domain	BROMO	BAZ2B BRPF1	5.87e-03	42	51	2	SM00297
Domain	Bromodomain	BAZ2B BRPF1	5.87e-03	42	51	2	IPR001487
Domain	-	BAZ2B BRPF1	5.87e-03	42	51	2	1.20.920.10
Domain	6-blade_b-propeller_TolB-like	TENM4 TENM3	7.01e-03	46	51	2	IPR011042
Pathway	REACTOME_INTERACTION_BETWEEN_L1_AND_ANKYRINS	SPTBN4 SPTBN5 SPTB	1.97e-06	10	37	3	MM15112
Pathway	REACTOME_INTERACTION_BETWEEN_L1_AND_ANKYRINS	SPTBN4 SPTBN5 SPTB	7.11e-05	31	37	3	M877
Pathway	REACTOME_NCAM_SIGNALING_FOR_NEURITE_OUT_GROWTH	SPTBN4 SPTBN5 SPTB	1.32e-04	38	37	3	MM14969
Pubmed	alphaII-betaV spectrin bridges the plasma membrane and cortical lattice in the lateral wall of the auditory outer hair cells.	SPTBN4 SPTBN5 SPTB	9.45e-07	13	53	3	18796539
Pubmed	Construction of expression-ready cDNA clones for KIAA genes: manual curation of 330 KIAA cDNA clones.	TENM4 DST SYNE2 PLEKHA5 SCRIB HPS5	1.22e-06	225	53	6	12168954
Pubmed	Regulation of Pulmonary Bacterial Immunity by Follistatin-Like Protein 1.	FSTL1 IL17RA	2.28e-06	2	53	2	33077624
Pubmed	Teneurins assemble into presynaptic nanoclusters that promote synapse formation via postsynaptic non-teneurin ligands.	TENM4 TENM3	2.28e-06	2	53	2	35484136
Pubmed	Histamine deficiency decreases atherosclerosis and inflammatory response in apolipoprotein E knockout mice independently of serum cholesterol level.	APOE HDC	2.28e-06	2	53	2	21273563
Pubmed	FRP inhibits ox-LDL-induced endothelial cell apoptosis through an Akt-NF-{kappa}B-Bcl-2 pathway and inhibits endothelial cell apoptosis in an apoE-knockout mouse model.	FSTL1 APOE	2.28e-06	2	53	2	20530739
Pubmed	Organization of focal adhesion plaques is disrupted by action of the HIV-1 protease.	SPTBN4 SPTBN5 SPTB	2.68e-06	18	53	3	12119179
Pubmed	Identifications of novel host cell factors that interact with the receptor-binding domain of the SARS-CoV-2 spike protein.	DST SUPT5H PLEKHA5 SCRIB HPS5 GARRE1 ITPR1 HR	6.02e-06	650	53	8	38777146
Pubmed	A new spectrin, beta IV, has a major truncated isoform that associates with promyelocytic leukemia protein nuclear bodies and the nuclear matrix.	SPTBN4 SPTB	6.83e-06	3	53	2	11294830
Pubmed	Histamine promotes the differentiation of macrophages from CD11b+ myeloid cells and formation of foam cells through a Stat6-dependent pathway.	APOE HDC	6.83e-06	3	53	2	28600950
Pubmed	The polarity protein Scribble positions DLC3 at adherens junctions to regulate Rho signaling.	STARD8 SCRIB	6.83e-06	3	53	2	27505894
Pubmed	The IL-17A/IL-17RA axis plays a proatherogenic role via the regulation of aortic myeloid cell recruitment.	IL17RA APOE	6.83e-06	3	53	2	22302786
Pubmed	β spectrin-dependent and domain specific mechanisms for Na+ channel clustering.	SPTBN4 SPTB	6.83e-06	3	53	2	32425157
Pubmed	Alanine and arginine rich domain containing protein, Aard, is directly regulated by androgen receptor in mouse Sertoli cells.	AARD PLEKHA5	6.83e-06	3	53	2	27959439
Pubmed	Nodal β spectrins are required to maintain Na+ channel clustering and axon integrity.	SPTBN4 SPTB	6.83e-06	3	53	2	32052742
Pubmed	Human Sos1: a guanine nucleotide exchange factor for Ras that binds to GRB2.	SPTBN4 SPTBN5 SPTB	7.51e-06	25	53	3	8493579
Pubmed	Kelch Domain of Gigaxonin Interacts with Intermediate Filament Proteins Affected in Giant Axonal Neuropathy.	SPTBN5 DST TENM3 SPTB SYNE2	9.91e-06	187	53	5	26460568
Pubmed	Mouse ten-m/Odz is a new family of dimeric type II transmembrane proteins expressed in many tissues.	TENM4 TENM3	1.36e-05	4	53	2	10225957
Pubmed	Genetic and age related models of neurodegeneration in mice: dystrophic axons.	SPTBN4 DST	1.36e-05	4	53	2	1634998
Pubmed	Epsin-mediated degradation of IP3R1 fuels atherosclerosis.	APOE ITPR1	1.36e-05	4	53	2	32770009
Pubmed	All four members of the Ten-m/Odz family of transmembrane proteins form dimers.	TENM4 TENM3	1.36e-05	4	53	2	12000766
Pubmed	Major vault protein suppresses obesity and atherosclerosis through inhibiting IKK-NF-κB signaling mediated inflammation.	APOE MVP	1.36e-05	4	53	2	30996248
Pubmed	N-Terminomics for the Identification of In Vitro Substrates and Cleavage Site Specificity of the SARS-CoV-2 Main Protease.	NES RBM15 DST SPTB PLEKHA5 MVP	1.80e-05	360	53	6	33111431
Pubmed	Retinal axon misrouting at the optic chiasm in mice with neural tube closure defects.	NES SCRIB	2.27e-05	5	53	2	10862153
Pubmed	A Common Embryonic Origin of Stem Cells Drives Developmental and Adult Neurogenesis.	NES APOE	2.27e-05	5	53	2	30929900
Pubmed	A central chaperone-like role for 14-3-3 proteins in human cells.	KIF13B NES RBM15 DST SYNE2 PLEKHA5 SCRIB GARRE1	4.52e-05	861	53	8	36931259
Pubmed	Distribution of a reeler gene-related antigen in the developing cerebellum: an immunohistochemical study with an allogeneic antibody CR-50 on normal and reeler mice.	NES ITPR1	4.76e-05	7	53	2	8863127
Pubmed	The mammalian Odz gene family: homologs of a Drosophila pair-rule gene with expression implying distinct yet overlapping developmental roles.	TENM4 TENM3	4.76e-05	7	53	2	10625539
Pubmed	The murine Ten-m/Odz genes show distinct but overlapping expression patterns during development and in adult brain.	TENM4 TENM3	4.76e-05	7	53	2	12915301
Pubmed	Functional proteomics establishes the interaction of SIRT7 with chromatin remodeling complexes and expands its role in regulation of RNA polymerase I transcription.	NES RBM15 DST SUPT5H SYNE2 EIF3E MVP	5.80e-05	653	53	7	22586326
Pubmed	Mapping homologs of Drosophila odd Oz (odz): Doc4/Odz4 to mouse chromosome 7, Odz1 to mouse chromosome 11; and ODZ3 to human chromosome Xq25.	TENM4 TENM3	6.34e-05	8	53	2	10331952
Pubmed	Progranulin expression in the developing and adult murine brain.	NES SUPT5H	6.34e-05	8	53	2	20737593
Pubmed	Cartography of teneurin and latrophilin expression reveals spatiotemporal axis heterogeneity in the mouse hippocampus during development.	TENM4 TENM3	1.02e-04	10	53	2	38713721
Pubmed	Brain proteins interacting with the tetramerization region of non-erythroid alpha spectrin.	SPTBN4 SPTB	1.24e-04	11	53	2	17607528
Pubmed	Chr21 protein-protein interactions: enrichment in proteins involved in intellectual disability, autism, and late-onset Alzheimer's disease.	SPTBN4 CRYL1 DST SUPT5H SPTB SCRIB APOE PDCD7 MVP	1.28e-04	1285	53	9	35914814
Pubmed	Excess LINC complexes impair brain morphogenesis in a mouse model of recessive TOR1A disease.	NES SYNE2	1.49e-04	12	53	2	29868845
Pubmed	Prediction of the coding sequences of mouse homologues of KIAA gene: III. the complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.	DST FBF1 PLEKHA5 HPS5 GARRE1 ANKS3	1.51e-04	529	53	6	14621295
Pubmed	SUN1/2 and Syne/Nesprin-1/2 complexes connect centrosome to the nucleus during neurogenesis and neuronal migration in mice.	NES SYNE2	2.05e-04	14	53	2	19874786
Pubmed	Gene expression analysis of the embryonic subplate.	NES SYNE2 APOE ITPR1	2.31e-04	196	53	4	21862448
Pubmed	Early loss of Scribble affects cortical development, interhemispheric connectivity and psychomotor activity.	NES SCRIB	2.70e-04	16	53	2	33907211
Pubmed	Temporal patterning of apical progenitors and their daughter neurons in the developing neocortex.	NES TENM3 ITPR1	2.72e-04	82	53	3	31073041
Pubmed	KCTD13-mediated ubiquitination and degradation of GluN1 regulates excitatory synaptic transmission and seizure susceptibility.	SPTBN4 CRACD NES TENM4 DST SPTB PLEKHA5 SCRIB APOE	2.85e-04	1431	53	9	37142655
Pubmed	Fstl1 is involved in the regulation of radial glial scaffold development.	NES FSTL1	3.05e-04	17	53	2	26382033
Pubmed	Scanning the human proteome for calmodulin-binding proteins.	DST SYNE2 PDCD7	3.81e-04	92	53	3	15840729
Pubmed	Prediction of the coding sequences of mouse homologues of KIAA gene: II. The complete nucleotide sequences of 400 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.	CRACD TENM4 TENM3 RIPOR1 SCRIB	3.87e-04	407	53	5	12693553
Pubmed	A quantitative survey of gravity receptor function in mutant mouse strains.	SPTBN4 HR	4.25e-04	20	53	2	16235133
Pubmed	An empirical framework for binary interactome mapping.	CNNM3 FSTL1 USHBP1 FBF1	4.30e-04	231	53	4	19060904
Pubmed	A Multipronged Unbiased Strategy Guides the Development of an Anti-EGFR/EPHA2-Bispecific Antibody for Combination Cancer Therapy.	CNNM3 DST TENM3 PLEKHA5 SCRIB	4.52e-04	421	53	5	36976175
Pubmed	mTOR Inhibition via Rapamycin Treatment Partially Reverts the Deficit in Energy Metabolism Caused by FH Loss in RPE Cells.	DST SPTB SYNE2	4.59e-04	98	53	3	34943047
Pubmed	ZZW-115-dependent inhibition of NUPR1 nuclear translocation sensitizes cancer cells to genotoxic agents.	NES RBM15 DST SUPT5H EIF3E SCRIB	4.91e-04	660	53	6	32780723
Pubmed	Sertoli Cell Wt1 Regulates Peritubular Myoid Cell and Fetal Leydig Cell Differentiation during Fetal Testis Development.	NES PLEKHA5	5.65e-04	23	53	2	28036337
Pubmed	Protein interaction network of the mammalian Hippo pathway reveals mechanisms of kinase-phosphatase interactions.	RBM15 DST FBF1 PLEKHA5 GARRE1	5.87e-04	446	53	5	24255178
Pubmed	Spatiotemporal profile of postsynaptic interactomes integrates components of complex brain disorders.	SPTBN4 KIF13B NES DST SYNE2 PLEKHA5 SCRIB	6.20e-04	963	53	7	28671696
Pubmed	An improved smaller biotin ligase for BioID proximity labeling.	DST SYNE2 HPS5	8.89e-04	123	53	3	26912792
Pubmed	Identifying biological pathways that underlie primordial short stature using network analysis.	CNNM3 NES RBM15 DST SUPT5H SYNE2 SCRIB	8.90e-04	1024	53	7	24711643
Pubmed	Fibril treatment changes protein interactions of tau and α-synuclein in human neurons.	CRACD NES DST SYNE2 SCRIB	9.62e-04	498	53	5	36634849
Pubmed	LZTR1 is a regulator of RAS ubiquitination and signaling.	CNNM3 PLEKHA5 SCRIB	9.75e-04	127	53	3	30442766
Pubmed	HSF1 phosphorylation establishes an active chromatin state via the TRRAP-TIP60 complex and promotes tumorigenesis.	RBM15 NAT14 SYNE2 EIF3E RIPOR1 ITPR1	9.83e-04	754	53	6	35906200
Pubmed	A comprehensive SARS-CoV-2-human protein-protein interactome reveals COVID-19 pathobiology and potential host therapeutic targets.	CRACD NES PLEKHA5 GARRE1 ITPR1	1.01e-03	503	53	5	36217030
Pubmed	A probability-based approach for high-throughput protein phosphorylation analysis and site localization.	RBM15 PLEKHA5 SCRIB CTU1 ANKS3	1.01e-03	503	53	5	16964243
Pubmed	MECP2 directly interacts with RNA polymerase II to modulate transcription in human neurons.	NES RBM15 DST SUPT5H GPC2 PDCD7 MVP	1.22e-03	1082	53	7	38697112
Pubmed	α-catenin interaction with YAP/FoxM1/TEAD-induced CEP55 supports liver cancer cell migration.	PLEKHA5 SCRIB	1.31e-03	35	53	2	37381005
Pubmed	SLMAP3 is essential for neurulation through mechanisms involving cytoskeletal elements, ABP, and PCP.	NES SCRIB	1.31e-03	35	53	2	39366759
Pubmed	Characterization of an exchangeable gene trap using pU-17 carrying a stop codon-beta geo cassette.	TENM4 TENM3 PLEKHA5 ITPR1 TEDC1	1.33e-03	536	53	5	15840001
Pubmed	Exchangeable gene trap using the Cre/mutated lox system.	TENM4 TENM3 PLEKHA5 ITPR1 TEDC1	1.35e-03	538	53	5	10512203
Pubmed	Genomic cloning of mouse MIF (macrophage inhibitory factor) and genetic mapping of the human and mouse expressed gene and nine mouse pseudogenes.	APOE HDC	1.39e-03	36	53	2	7558020
Pubmed	Novel genetic loci identified for the pathophysiology of childhood obesity in the Hispanic population.	CRYL1 TENM4 FSTL1 SPTB ITPR1 HR	1.45e-03	814	53	6	23251661
Pubmed	Cell-Type-Specific Alternative Splicing Governs Cell Fate in the Developing Cerebral Cortex.	SYNE2 SCRIB	1.47e-03	37	53	2	27565344
Pubmed	A RECQ5-RNA polymerase II association identified by targeted proteomic analysis of human chromatin.	SUPT5H EIF3E	1.47e-03	37	53	2	18562274
Pubmed	Protein interactome mining defines melatonin MT1 receptors as integral component of presynaptic protein complexes of neurons.	DST FSTL1 TENM3 SYNE2	1.48e-03	322	53	4	26514267
Cytoband	Ensembl 112 genes in cytogenetic band chr19q13	SPTBN4 NAT14 SUPT5H APOE GARRE1 CTU1 PPM1N	4.78e-04	1192	54	7	chr19q13
GeneFamily	EF-hand domain containing\|Spectrins	SPTBN4 SPTBN5 SPTB	1.59e-07	7	31	3	1113
GeneFamily	Pleckstrin homology domain containing\|Rho guanine nucleotide exchange factors\|C2 domain containing	SPTBN4 SPTB PLEKHA5	5.18e-03	206	31	3	682
GeneFamily	PHD finger proteins	BAZ2B BRPF1	1.04e-02	90	31	2	88
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Epithelial-Renal_corpuscle_epithelial_cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	CRACD NES DST TENM3 RIPOR1	1.87e-06	168	54	5	315ca578c945aeeb77acda2727f3e6db8b43f43e
ToppCell	renal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Renal_corpuscle_epithelial_cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	CRACD DST TENM3 SPTB RIPOR1	2.55e-06	179	54	5	7394e77e665bf16d3733df91bb12907be460ab44
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Epithelial-Renal_corpuscle_epithelial_cell-glomerular_visceral_epithelial_cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	CRACD NES TENM3 SPTB RIPOR1	2.84e-06	183	54	5	612d93df03252d4d2ccdce5a9bc162cfd9172a1a
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Epithelial-Renal_corpuscle_epithelial_cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	CRACD NES TENM3 SPTB RIPOR1	2.84e-06	183	54	5	7c4b775f351794a3de06bd503eecbc8ae8577c44
ToppCell	Brain_organoid-organoid_Kanton_Nature\|Brain_organoid / Sample Type, Dataset, Time_group, and Cell type.	NES BAZ2B SYNE2 GPC2 PDCD7	2.99e-06	185	54	5	857c7ca8493e91ef1d0078ddafd6082020f9b169
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Renal_corpuscle_epithelial_cell-glomerular_visceral_epithelial_cell-Podocyte\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	CRACD NES DST TENM3 RIPOR1	2.99e-06	185	54	5	9197f074e769d54031ec41abfc65fcc0c6552c7e
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Renal_corpuscle_epithelial_cell-glomerular_visceral_epithelial_cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	CRACD NES DST TENM3 RIPOR1	2.99e-06	185	54	5	ce7d62394b09c26ca65b8cdb280afec5e25bbb62
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Renal_corpuscle_epithelial_cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	CRACD NES DST TENM3 RIPOR1	2.99e-06	185	54	5	b848b63aff4d9dbb9e66a85876d4c7c6dacd0579
ToppCell	3'-Adult-Appendix-Endothelial-blood_vessel_EC\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	NES USHBP1 RIPOR1 DYNLT4 ITPR1	3.15e-06	187	54	5	37d8ee5c8bd6324749e5a2adef1d0482c75da80c
ToppCell	3'-Adult-Appendix-Endothelial\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	NES USHBP1 RIPOR1 DYNLT4 ITPR1	3.15e-06	187	54	5	ec98d5e480b08854dfd0ba6b1dc6610455f90640
ToppCell	facs-BAT-Fat-3m-Endothelial-nan\|BAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	NES DST USHBP1 RIPOR1 GARRE1	3.68e-06	193	54	5	e340064cd146deac03f2d0fd43e2e218bb6057c9
ToppCell	droplet-Lung-nan-21m-Endothelial-Capillary_Aerocyte_endothelial_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	NES STARD8 AARD USHBP1 RIPOR1	3.68e-06	193	54	5	ffdcbc5caff7fd4cc2e83dd21a05d43b0593d542
ToppCell	facs-BAT-Fat-3m-Endothelial-endothelial_cell\|BAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	NES DST USHBP1 RIPOR1 GARRE1	3.68e-06	193	54	5	a211b386fd0fb9da9937361d29d90925a72c9715
ToppCell	facs-BAT-Fat-3m-Endothelial\|BAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	NES DST USHBP1 RIPOR1 GARRE1	3.68e-06	193	54	5	3086c33f4d6fab66966818737f95ae4d6b2615b0
ToppCell	Control-Fibroblasts-Intermediate_pathological_FB\|Control / group, cell type (main and fine annotations)	CRACD TENM4 DST FSTL1 TENM3	3.77e-06	194	54	5	03a269f75a481ea54aea8e6444605db8d6df493d
ToppCell	COVID-19-Fibroblasts-Intermediate_pathological_FB\|COVID-19 / group, cell type (main and fine annotations)	CRACD TENM4 DST FSTL1 TENM3	4.06e-06	197	54	5	f1c8936986123a3151140c374fcd62d6705c530b
ToppCell	IPF-Stromal-Myofibroblast\|Stromal / Disease state, Lineage and Cell class	KIF13B CRACD TENM4 TENM3 PLEKHA5	4.06e-06	197	54	5	f304d42fc4936fe20996e07c8dccc698a6e5e5ef
ToppCell	LPS_IL1RA-Endothelial-Endothelial-Gen_Cap\|LPS_IL1RA / Treatment groups by lineage, cell group, cell type	DST USHBP1 BAZ2B SYNE2 GARRE1	4.37e-06	200	54	5	dccec522ab0d7fff62ad6273b02aa9022dbbb8eb
ToppCell	LPS_anti-TNF-Endothelial-Endothelial-Gen_Cap\|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type	DST USHBP1 BAZ2B SYNE2 GARRE1	4.37e-06	200	54	5	a2b9d1cd291d17abddc3ee2e242121412c864b8b
ToppCell	PBMC-Mild-cDC_2\|Mild / Compartment, Disease Groups and Clusters	CRACD FSTL1 AARD SYNE2	2.18e-05	135	54	4	cb9d834f8301cf53f20e09c3f4cb6a148690196a
ToppCell	Adult-Immune-mast_cell-D122\|Adult / Lineage, Cell type, age group and donor	AARD SPTB GAL3ST2 HDC	3.75e-05	155	54	4	7c9de0591d1bf756b8e268b278bbe10bd5415dcd
ToppCell	PND14-Immune-Immune_Lymphocytic_T/NK-Lymphocytic_T-CD4_T-CD4_T_G2M\|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	CRYL1 FBF1 IL17RA TEDC1	5.62e-05	172	54	4	ba36581ae339191a12a6d3ead39eaf69d78be10e
ToppCell	Bronchial_Biopsy-Immune-Mast_cells\|Bronchial_Biopsy / Tissue, Lineage and Cell class of Lung Cells from 10X	ABCA3 AARD APOE HDC	5.62e-05	172	54	4	c477008444d2d71071177807870d7455e90c2fad
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Renal_corpuscle_epithelial_cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	NES DST TENM3 RIPOR1	5.62e-05	172	54	4	6c17a1e586a72d1bd80c20c06370429c61dc9f85
ToppCell	facs-Brain_Non-Myeloid-Cortex-3m-Mesenchymal-ependymal_cell\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	AARD WDR27 DYNLT4 HDC	5.75e-05	173	54	4	a7cc63bb3ab41feb9e4072700d44dbbbc62c47c6
ToppCell	facs-Brain_Non-Myeloid-Cortex-3m-Mesenchymal-Ependyma\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	AARD WDR27 DYNLT4 HDC	5.75e-05	173	54	4	e3e3a67a5a93ef4475224a256d45ae24526383cc
ToppCell	10x5'-bone_marrow-Myeloid_Mac-Intestinal_macrophages\|bone_marrow / Manually curated celltypes from each tissue	SPTBN5 DST APOE PPM1N	5.88e-05	174	54	4	0746344d62aa7ab77c378e9d5a9f9238e741a76b
ToppCell	facs-Lung-Endomucin-3m-Endothelial-Vein_endothelial_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	RBM15 DST FSTL1 HDC	6.42e-05	178	54	4	5cc182e6faa7ba5b88378d2c953be29bbbb95a7e
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Renal_corpuscle_epithelial_cell-glomerular_visceral_epithelial_cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	CRACD NES SPTB RIPOR1	6.42e-05	178	54	4	edc7143dc9959d36057cb9471681a23afcbc8cce
ToppCell	facs-Lung-Endomucin-3m-Endothelial-vein_endothelial_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	RBM15 DST FSTL1 HDC	6.42e-05	178	54	4	f9a16bc3f09c35c7d30e3809da024bc2dcf746ed
ToppCell	PND10-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_airway-SCMF-SCMF_prolif\|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	NES TENM4 FSTL1 AARD	6.56e-05	179	54	4	ff678e2f33c914e3dd0f338ada25f506c3e3c980
ToppCell	facs-Marrow-B-cells-18m-Hematologic-MPP_Fraction_B_+_C\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SPTBN4 CNNM3 WDR27 GPC2	6.70e-05	180	54	4	7368ab31c3273374ef260f0d710d4eea83cbc4a2
ToppCell	5'-Adult-Appendix-Neuronal-Glial_mature\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	NAT14 TENM4 TENM3 APOE	6.85e-05	181	54	4	3aa81ac64d0cc9a74fbfa71e2176740548e7cd06
ToppCell	5'-Adult-Appendix-Neuronal-Glial_mature-Adult_Glia\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	NAT14 TENM4 TENM3 APOE	6.85e-05	181	54	4	997ba1be2824b00d684f2163d0114656ed11fa53
ToppCell	renal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Renal_corpuscle_epithelial_cell-glomerular_visceral_epithelial_cell-Podocyte\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	CRACD DST SPTB RIPOR1	6.85e-05	181	54	4	5bf7aa43f6e6ecce15c95928b91195544d6928c4
ToppCell	5'-Adult-Appendix-Neuronal\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	NAT14 TENM4 TENM3 APOE	6.85e-05	181	54	4	e6b7e8dd5c13cc10ba22f2f5a8c669486f934bdc
ToppCell	renal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Renal_corpuscle_epithelial_cell-glomerular_visceral_epithelial_cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	CRACD DST SPTB RIPOR1	6.85e-05	181	54	4	8e751f5d7cd2d328ec0196d874e8a507e8c4e1a9
ToppCell	PND01-03-samps-Mesenchymal-Myofibroblast\|PND01-03-samps / Age Group, Lineage, Cell class and subclass	DST FSTL1 TENM3 MFHAS1	7.00e-05	182	54	4	812dac35b9aa05be48258082e007f6c00e7b4dd8
ToppCell	droplet-Heart-nan-3m-Endothelial-endothelial_cell_of_coronary_artery\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	NES USHBP1 SYNE2 GARRE1	7.00e-05	182	54	4	81279877b920b5a1bc991a07d3031d6458700fe3
ToppCell	COVID-19-kidney-Podocyte\|kidney / Disease (COVID-19 only), tissue and cell type	CRACD NES TENM3 RIPOR1	7.15e-05	183	54	4	fb5e2a31b560126e1c04a386c24c365901c60ad7
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Renal_corpuscle_epithelial_cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	CRACD NES TENM3 RIPOR1	7.15e-05	183	54	4	848fc6dd129150897ee339343e83c645b6e779eb
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Epithelial-Renal_corpuscle_epithelial_cell-glomerular_visceral_epithelial_cell-Podocyte\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	CRACD TENM3 SPTB RIPOR1	7.15e-05	183	54	4	eb559ae3ae252d9365c24ef557dd49b78ed6d898
ToppCell	PND07-28-samps-Epithelial\|PND07-28-samps / Age Group, Lineage, Cell class and subclass	ABCA3 WDR27 DYNLT4 HDC	7.15e-05	183	54	4	a98f1d71d82ed6cca996f74352ab834fb6e95206
ToppCell	3'-Adult-Appendix-Endothelial-blood_vessel_EC-Mature_arterial_EC\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	NES USHBP1 DYNLT4 ITPR1	7.45e-05	185	54	4	fa94c4a1660967f211ba095606cd0aa37d38e17a
ToppCell	kidney_cells-Adult_normal_reference-Epithelial-Renal_corpuscle_epithelial_cell-glomerular_visceral_epithelial_cell-Podocyte\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	NES DST SPTB RIPOR1	7.77e-05	187	54	4	24c2a3962da364e46e98abeab5f8234376fa26bb
ToppCell	droplet-Lung-3m-Endothelial-capillary_endothelial-capillary_endothelial_cell-capillary_aerocyte_endothelial_cell\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	NES STARD8 AARD USHBP1	7.93e-05	188	54	4	db0652f000d459493321b53239326706eace598c
ToppCell	facs-Pancreas-Endocrine-3m-Epithelial-nan\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DST AARD EFCC1 ITPR1	7.93e-05	188	54	4	e99e3765b48392c987cf0c5ccbded0655637d7b7
ToppCell	Fetal_29-31_weeks-Mesenchymal-airway_smooth_muscle_cell-D062\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	NES NAT14 FSTL1 HR	7.93e-05	188	54	4	c29aaae3c5bb7cd6b9b3defd4d27afde3af19ba0
ToppCell	COVID_vent-Myeloid-Monocytic-SC_&_Eosinophil\|COVID_vent / Disease condition, Lineage, Cell class and subclass	CRACD DST FSTL1 HDC	8.10e-05	189	54	4	2157a2d40613f7d5ce2e7dbd266df441e449cdaf
ToppCell	facs-Brain_Non-Myeloid-Striatum_-18m-Neuronal\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SPTBN4 SPTB PLEKHA5 ITPR1	8.10e-05	189	54	4	3d838da870623a6a278ddc8e6cedca85d9877e50
ToppCell	facs-Trachea-24m-Endothelial-endothelial_cell_of_trachea-tracheal_endothelial_cell\|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	NES USHBP1 RIPOR1 GARRE1	8.43e-05	191	54	4	79b399496bd7322a1d53c43378f48695fd09a5d9
ToppCell	facs-Trachea-24m-Endothelial\|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	NES USHBP1 RIPOR1 GARRE1	8.43e-05	191	54	4	9c6d5d045781c6506ae80e318427ef1e0d87f45c
ToppCell	facs-Skin\|facs / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TENM4 SYNE2 APOE HR	8.43e-05	191	54	4	ae524103331fa53fa82888dbb567fc36abcee7e0
ToppCell	facs-Trachea-24m-Endothelial-endothelial_cell_of_trachea\|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	NES USHBP1 RIPOR1 GARRE1	8.43e-05	191	54	4	1b1e943709d0c3283a980c7c965ef1f110506a29
ToppCell	kidney_cells-Adult_normal_reference-Epithelial-Renal_corpuscle_epithelial_cell-glomerular_visceral_epithelial_cell-Degenerative_Podocyte\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	NES DST SPTB RIPOR1	8.60e-05	192	54	4	ef0aba777072429a6ab7dcfcc305673975946580
ToppCell	droplet-Lung-nan-21m-Endothelial-endothelial_cell_of_lung\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	NES AARD USHBP1 GARRE1	8.78e-05	193	54	4	ff048e7fbab95d7914f3a636f6f014e7115d63d8
ToppCell	kidney_cells-Adult_normal_reference-Epithelial-Renal_corpuscle_epithelial_cell-glomerular_visceral_epithelial_cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	NES DST SPTB RIPOR1	8.78e-05	193	54	4	3eaa0461618582a1754400624350d269d24e750a
ToppCell	droplet-Lung-nan-3m-Endothelial-Capillary_endothelial_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	AARD USHBP1 RIPOR1 GARRE1	8.78e-05	193	54	4	7cff1e859b296b1032eebcfc0f99a504f3bda2c9
ToppCell	droplet-Lung-3m-Endothelial-capillary_endothelial\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	NES AARD USHBP1 GARRE1	8.78e-05	193	54	4	1b6317b740cad2439f08b9e9895426d861e7a161
ToppCell	COVID-19-Fibroblasts-Other_FB\|COVID-19 / group, cell type (main and fine annotations)	CRACD TENM4 DST PLEKHA5	8.78e-05	193	54	4	e6b75be08e33c1de079fb5c02f0b4468128b369c
ToppCell	droplet-Lung-3m-Endothelial-capillary_endothelial-capillary_endothelial_cell\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	NES AARD USHBP1 GARRE1	8.78e-05	193	54	4	f5861cfa4401b476229a7c61cd64abad79a4bbfc
ToppCell	droplet-Lung-3m-Endothelial\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	NES AARD USHBP1 GARRE1	8.78e-05	193	54	4	95c9c63bddfed1a84393ccd3578cfe65bc0c1c05
ToppCell	PND07-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_airway-SCMF-SCMF_prolif\|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	NES TENM4 FSTL1 AARD	8.78e-05	193	54	4	f25bdd10ef531b8d8441ea84573078b4b1b0f105
ToppCell	droplet-Lung-nan-3m-Endothelial-endothelial_cell_of_lung\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	NES AARD USHBP1 GARRE1	8.78e-05	193	54	4	ab54c4b8ae17580e2f2bfcdcb1456fe52dedafe9
ToppCell	droplet-Lung-1m-Endothelial\|1m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	NES AARD USHBP1 GARRE1	8.95e-05	194	54	4	b1a25e3b36e7b7e558ef95ec22a3bdcbceae821f
ToppCell	droplet-Lung-LUNG-1m-Endothelial\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	NES AARD USHBP1 GARRE1	8.95e-05	194	54	4	68efc6df31479839a3bd5fe9fbc98ddceecc3b10
ToppCell	PND14-Endothelial-Endothelial_blood-vessel-Microvascular_EC\|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	NES STARD8 USHBP1 GARRE1	8.95e-05	194	54	4	c6cee7d15af76f9a60d7f414ef0bcc1735c47b7a
ToppCell	facs-Thymus-Epithelium\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DST USHBP1 APOE HR	8.95e-05	194	54	4	255d6eead8da740a942a5e7d554dbd895d736d1a
ToppCell	PND03-Endothelial-Endothelial_blood-vessel-Microvascular_EC\|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	NES STARD8 USHBP1 GARRE1	9.13e-05	195	54	4	d700e959e060932e3854a9cf294799465efbe18b
ToppCell	10x3'2.3-week_17-19-Mesenchymal_osteo-stroma-osteoblast_precursor\|week_17-19 / cell types per 3 fetal stages;per 3',per 5'	NES TENM4 FSTL1 TENM3	9.13e-05	195	54	4	ec12cfb2fce44cc2de4e198ef5af075e626f0329
ToppCell	P07-Mesenchymal-myocytic_cell\|P07 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	NES TENM4 FSTL1 AARD	9.50e-05	197	54	4	378299fe2ec6ed2fc858febb78ff1ac0898e457d
ToppCell	LPS_anti-TNF-Mesenchymal_fibroblastic-Fibroblasts-Activated_MatrixFB\|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type	DST FSTL1 TENM3 APOE	9.50e-05	197	54	4	fdb92985f7df0c280b87d3e43c2394e70786a2c7
ToppCell	10x5'v1-week_12-13-Mesenchymal_osteo-stroma-early_osteoblast\|week_12-13 / cell types per 3 fetal stages;per 3',per 5'	NES TENM4 FSTL1 TENM3	9.50e-05	197	54	4	2ca5ebb708935a90b12b8e98a22ae2d664ed002e
ToppCell	Brain_organoid-organoid_Paulsen_bioRxiv-6_mon\|organoid_Paulsen_bioRxiv / Sample Type, Dataset, Time_group, and Cell type.	NES DST FSTL1 APOE	9.50e-05	197	54	4	58b957efd006f43c2fe55071d5c6d06c2e367e72
ToppCell	P03-Mesenchymal-myocytic_cell-aortic_smooth_muscle_cell\|P03 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	NES TENM4 FSTL1 AARD	9.50e-05	197	54	4	2cec938caf6ffd031cea37277071487e59b2c71c
ToppCell	P03-Mesenchymal-myocytic_cell\|P03 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	NES TENM4 FSTL1 AARD	9.50e-05	197	54	4	079db904a08743b3c555cb7b3f5fb5c978dde25a
ToppCell	P07-Mesenchymal-myocytic_cell-aortic_smooth_muscle_cell\|P07 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	NES TENM4 FSTL1 AARD	9.50e-05	197	54	4	b1135378d768fbbe62a75747d1e8653d35252187
ToppCell	Brain_organoid-organoid_Velasco_nature-6_mon\|organoid_Velasco_nature / Sample Type, Dataset, Time_group, and Cell type.	NES DST FSTL1 APOE	9.69e-05	198	54	4	a6f65bb0845d8f64f5c7edb00cee3ca5adb1a373
ToppCell	5'-GW_trimst-2-SmallIntestine-Neuronal-Glial_immature\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	NES DST TENM3 APOE	9.69e-05	198	54	4	50dfe6efca76ea9683a19b6bff59cb5030d346f1
ToppCell	Primary_Visual_cortex_(V1C)-Neuronal\|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	SPTBN4 TENM4 PLEKHA5 ITPR1	9.69e-05	198	54	4	8ab40fae14fe02e39bc8c8da187a5cd60c787643
ToppCell	wk_15-18-Hematologic-Myeloid-APOE+_Mac1\|wk_15-18 / Celltypes from embryonic and fetal-stage human lung	CRYL1 APOE HPS5 PPM1N	9.69e-05	198	54	4	88182ad964db88cf85b3e3a64929d07d59a923c2
ToppCell	LPS_IL1RA-Mesenchymal_fibroblastic-Fibroblasts-MatrixFB\|LPS_IL1RA / Treatment groups by lineage, cell group, cell type	DST FSTL1 TENM3 APOE	9.88e-05	199	54	4	a7dd94b172c973a131a6792f8ccd9bfe44d984ac
ToppCell	5'-GW_trimst-1.5-SmallIntestine-Mesenchymal-immature_mesenchymal_cell-Mesoderm_2_(ZEB2+)\|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	FSTL1 BAZ2B EIF3E PLEKHA5	9.88e-05	199	54	4	da016849b804fbf80edbfa8f8f56c9df8bbf2d51
ToppCell	(03)_KRT6B+-(2)_GFP_FOXI1\|(03)_KRT6B+ / shred by cell type by condition	DST BAZ2B SYNE2 HPS5	9.88e-05	199	54	4	c425e7975f492ed5cfcca022248adb627e1d27d4
ToppCell	LPS_IL1RA_TNF-Mesenchymal_fibroblastic-Fibroblasts-Activated_MatrixFB\|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type	DST FSTL1 TENM3 APOE	9.88e-05	199	54	4	e1849505b92820a219c5a2c35492bdd55579fb48
ToppCell	5'-GW_trimst-1.5-SmallIntestine-Mesenchymal-immature_mesenchymal_cell\|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	FSTL1 BAZ2B SYNE2 PLEKHA5	9.88e-05	199	54	4	3cf62666ffd000427fdbb7cf940793f98c3ed29c
ToppCell	LPS_IL1RA-Endothelial-Endothelial\|LPS_IL1RA / Treatment groups by lineage, cell group, cell type	DST USHBP1 SYNE2 GARRE1	1.01e-04	200	54	4	72ea9882a8ed26fa1534aeb6ba0d1897dccc20c5
ToppCell	Brain_organoid-organoid_Tanaka_cellReport-6m\|organoid_Tanaka_cellReport / Sample Type, Dataset, Time_group, and Cell type.	NES DST FSTL1 APOE	1.01e-04	200	54	4	5ba4ed490c64b3bb738e7729669f893fa73aa56f
ToppCell	LPS_IL1RA-Endothelial\|LPS_IL1RA / Treatment groups by lineage, cell group, cell type	DST USHBP1 SYNE2 GARRE1	1.01e-04	200	54	4	5c092b2ecc081b5d04476c56333c338cd89ab984
ToppCell	LPS_only-Endothelial\|LPS_only / Treatment groups by lineage, cell group, cell type	DST USHBP1 SYNE2 GARRE1	1.01e-04	200	54	4	81e76508c9050d533853d5fd2f3097b27613d836
ToppCell	Control_saline-Endothelial-Endothelial-Gen_Cap\|Control_saline / Treatment groups by lineage, cell group, cell type	DST USHBP1 BAZ2B GARRE1	1.01e-04	200	54	4	3b97920e1e6e2f09ddba2a861baa9c00c2970f4c
ToppCell	LPS_IL1RA_TNF-Endothelial-Endothelial-Artery\|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type	DST USHBP1 SYNE2 GARRE1	1.01e-04	200	54	4	77ae679c35d3b9e2b620f34129f3a8d47e922c65
ToppCell	Brain_organoid-organoid_Tanaka_cellReport-1m-Neuronal-Intermediate\|1m / Sample Type, Dataset, Time_group, and Cell type.	CRYL1 BAZ2B EIF3E GPC2	1.01e-04	200	54	4	805f50236113713b02f77aa5e208efb3b3b959d5
ToppCell	LPS_IL1RA_TNF-Endothelial-Endothelial-Gen_Cap\|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type	DST USHBP1 BAZ2B GARRE1	1.01e-04	200	54	4	b2d4e6f3e8e4da62e6b02758ab2ed8f505269f9a
ToppCell	LPS_anti-TNF-Endothelial-Endothelial-Artery\|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type	DST USHBP1 SYNE2 GARRE1	1.01e-04	200	54	4	b1ff8d61b567f85006d6d20093f9c803b6d34674
ToppCell	Control_saline-Mesenchymal_fibroblastic-Fibroblasts-MatrixFB\|Control_saline / Treatment groups by lineage, cell group, cell type	DST FSTL1 EFCC1 APOE	1.01e-04	200	54	4	bd8cf33502adea320e91ca2af14e1911d88ad374
ToppCell	LPS_only-Endothelial-Endothelial\|LPS_only / Treatment groups by lineage, cell group, cell type	DST USHBP1 SYNE2 GARRE1	1.01e-04	200	54	4	4bb609a284d4e6066f17470a1736076aa4a1f84c
ToppCell	saliva-Severe-critical_progression_d28-40-Lymphocytic-Lymphocytic_B-B_cell-B_c03-CD27-AIM2\|Severe-critical_progression_d28-40 / Compartment, severity and other cell annotations on 10x 3' data (130k)	KIF13B FSTL1 ANKS3	6.51e-04	140	54	3	af9efcbaeeae69fcdac4a15fa244728b65915564
ToppCell	LPS-antiTNF-Unknown-Endothelial-Monocytes-Macrophages\|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	CRACD NES CTU1	6.79e-04	142	54	3	b66f9602dba30d1d4fbcc49ceb112eb5bd916ba1
ToppCell	LPS-antiTNF-Epithelial_airway-Ciliated_cells-Ciliated\|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	RIBC2 DYNLT4 CFAP99	7.65e-04	148	54	3	d61123f0c811287843d066b932b4a9ff09c07c5b
Drug	2-nitro-5-thiocyanobenzoic acid	SPTBN4 SPTBN5 DST SPTB HDC	8.94e-08	48	53	5	CID000092266
Drug	plakin	SPTBN4 SPTBN5 DST SPTB SYNE2	1.34e-06	82	53	5	CID000018752
Drug	ADPribulose	SPTBN4 SPTBN5 SPTB	3.35e-06	13	53	3	CID000197570
Drug	dimyristoylphosphatidylcholine	SPTBN4 SPTBN5 SPTB APOE	1.50e-05	64	53	4	CID000026197
Disease	Sphingomyelin (d18:1/21:0, d17:1/22:0, d16:1/23:0) measurement	SYNE2 APOE	9.13e-06	3	52	2	EFO_0022111
Disease	N-palmitoyl-sphinganine (d18:0/16:0) measurement	SYNE2 APOE	9.13e-06	3	52	2	EFO_0800428
Disease	Sphingomyelin (d18:1/22:1, d18:2/22:0, d16:1/24:1) measurement	SYNE2 APOE	1.82e-05	4	52	2	EFO_0022112
Disease	Sphingomyelin (d18:2/23:0, d18:1/23:1, d17:1/24:1) measurement	SYNE2 APOE	1.82e-05	4	52	2	EFO_0022116
Disease	spinocerebellar ataxia type 5 (implicated_via_orthology)	SPTBN4 SPTB	1.82e-05	4	52	2	DOID:0050882 (implicated_via_orthology)
Disease	Sphingomyelin (d18:1/20:0, d16:1/22:0) measurement	SYNE2 APOE	3.04e-05	5	52	2	EFO_0022109
Disease	stearoyl sphingomyelin (d18:1/18:0) measurement	SYNE2 APOE	4.55e-05	6	52	2	EFO_0800611
Disease	FEV/FEC ratio	SPTBN5 ABCA3 DST SYNE2 EIF3E RIPOR1 TSEN54 CTU1 HDC ITPR1	4.82e-05	1228	52	10	EFO_0004713
Disease	very low density lipoprotein cholesterol measurement, phospholipids:total lipids ratio	TENM4 MFHAS1 SYNE2 TSEN54 APOE	1.60e-04	291	52	5	EFO_0008317, EFO_0020946
Disease	Pathological accumulation of air in tissues	ABCA3 APOE	1.99e-04	12	52	2	C0013990
Disease	low density lipoprotein cholesterol measurement, free cholesterol:total lipids ratio	MFHAS1 SYNE2 TSEN54 APOE	4.30e-04	200	52	4	EFO_0004611, EFO_0020945
Disease	Child Behaviour Checklist assessment	TENM4 TENM3	4.58e-04	18	52	2	EFO_0005661
Disease	very low density lipoprotein cholesterol measurement, cholesterol:total lipids ratio	MFHAS1 SYNE2 TSEN54 APOE	6.36e-04	222	52	4	EFO_0008317, EFO_0020943
Disease	HDL cholesterol change measurement	SYNE2 APOE	8.20e-04	24	52	2	EFO_0007805
Disease	Lewy body dementia, Lewy body dementia measurement	APOE HPS5	9.64e-04	26	52	2	EFO_0006792, EFO_0006799
Disease	age at assessment, lateral ventricle volume change measurement	TENM4 APOE	1.04e-03	27	52	2	EFO_0008007, EFO_0021502
Disease	Mental deterioration	TENM4 APOE	1.20e-03	29	52	2	HP_0001268
Disease	very low density lipoprotein cholesterol measurement, cholesteryl esters:total lipids ratio	MFHAS1 SYNE2 TSEN54 APOE	1.21e-03	264	52	4	EFO_0008317, EFO_0020944
Disease	proteinuria (implicated_via_orthology)	HPS5 HR	1.28e-03	30	52	2	DOID:576 (implicated_via_orthology)

Protein segments in the cluster

Peptide	Gene	Start	Entry
REAARLAERNAWLRL	USHBP1	171	Q8N6Y0
LEDLRRRLTRAFQWA	AARD	56	Q4LEZ3
LQERAQAWGERLRAR	APOE	221	P02649
LRVWRRALSEARSAA	BAZ2B	1896	Q9UIF8
DAISRRAIWDLLQRQ	ABCA3	696	Q99758
GLQRWVRRLEAELQR	EFCC1	311	Q9HA90
LDSLDRRRDGWSLDR	RBM15	611	Q96T37
AQHWLELERSRERRL	CFAP99	681	D6REC4
TRDDILRDWNLIRDA	HDC	456	P19113
QLRAALDRFRDWQVR	IL17RA	566	Q96F46
TARLWRDAALRARKL	MFHAS1	11	Q9Y4C4
WRLSARNAARRDSVL	ITPR1	1586	Q14643
ERWEAARAQRALEAA	DYNLT4	116	Q5JR98
NLHRLVWELRERLAR	GPC2	386	Q8N158
WLLALERRRKLNDAL	DST	7156	Q03001
VERLLRRGLWNLAAR	HPS5	361	Q9UPZ3
LCRLLRREREALAWA	HR	566	O43593
RRLLAFAEARARAWA	NAT14	141	Q8WUY8
AALQRLRDRQWLEAV	PDCD7	136	Q8N8D1
RRAFLSADERLRSLW	PPM1N	141	Q8N819
LERRAALEQRLEGRW	NES	236	P48681
ALEQRLEGRWQERLR	NES	241	P48681
QQWRRQRDLRRALDS	RIBC2	331	Q9H4K1
NQALRLRARKECWDR	MVP	171	Q14764
LLRRRLRWALDDVVA	GAL3ST2	236	Q9H3Q3
RLNEQSRLLEQERWR	FBF1	811	Q8TES7
DAALAAVRRQAARWE	CTU1	96	Q7Z7A3
QRLQALERRLWEENR	CRACD	251	Q6ZU35
LERRLWEENRRQELL	CRACD	256	Q6ZU35
SNRDELRRRIIQWLE	FSTL1	116	Q12841
VLDLNRWRAGREQAL	GARRE1	486	O15063
EAERWIVNLIRNARL	EIF3E	366	P60228
EDLQARLRETWALAR	ANKS3	551	Q6ZW76
LWRELLEAERRGQQR	C2orf50	71	Q96LR7
AARRQWRDECLMRLA	CRYL1	296	Q9Y2S2
ERRRALRQQGAEAWL	CYP4F22	281	Q6NT55
VRVLEARNLRWADLL	PLA2G4D	26	Q86XP0
RDLERLRRKWLNALT	KIF13B	1086	Q9NQT8
QAERLRRCREELWQL	TSEN54	51	Q7Z6J9
RRCREELWQLLAEQR	TSEN54	56	Q7Z6J9
WDNLQRRVTAVLRRL	SYNE2	6226	Q8WXH0
DEDRSGARRLQNLWR	SUPT5H	116	O00267
RALEAEKRALWRAAR	SCRIB	1491	Q14160
LRERALWDEDLLRAQ	STARD8	881	Q92502
EAASWLRERRSSLER	SPTBN5	756	Q9NRC6
WQRLRHDLERARLLV	BRPF1	591	P55201
EWRALLRLRLRAEAV	CNNM3	96	Q8NE01
AERAAARRLEPARRW	CNNM3	176	Q8NE01
ELLWRLARASRDVAQ	RMDN1	116	Q96DB5
NQRLEAVLAWRRSEL	TEDC1	306	Q86SX3
LELARQRAVRQAWAR	TENM4	2691	Q6N022
QAASLSWDRLARALR	TMDD1	121	P0DPE3
VTEVAALRRQWLRDA	SPTBN4	866	Q9H254
LEQARQRALARAWAR	TENM3	2621	Q9P273
WDRLREAAAGRLQRL	SPTB	1566	P11277
REALSRLRELCRQWL	ZKSCAN3	61	Q9BRR0
DRRWLLSAARDGTLR	WDR27	566	A2RRH5
RELSRATAELERAWR	PLEKHA5	706	Q9HAU0
QEAWALERLLREARV	RIPOR1	926	Q6ZS17