Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	G protein-coupled receptor activity	OR6B1 GPR25 GALR3 ADGRB2 OR1F12P OR1C1 RXFP3 TAAR8 OR6P1 OR1J2 HCAR3 OR6A2 OR1G1 RXFP4 ADGRF3 CX3CR1 ADGRA3	2.00e-06	884	101	17	GO:0004930
GeneOntologyMolecularFunction	alpha-L-arabinofuranosidase activity	OTOGL OTOG	2.53e-05	2	101	2	GO:0046556
GeneOntologyMolecularFunction	transmembrane signaling receptor activity	OR6B1 GPR25 GALR3 ADGRB2 OR1F12P OR1C1 RXFP3 TAAR8 OR6P1 OR1J2 MET HCAR3 OR6A2 OR1G1 RXFP4 ADGRF3 CX3CR1 ADGRA3	1.38e-04	1353	101	18	GO:0004888
GeneOntologyMolecularFunction	histone H3K36 dimethyltransferase activity	NSD1 SMYD3	1.51e-04	4	101	2	GO:0140954
GeneOntologyMolecularFunction	metalloendopeptidase activity	ADAM29 ADAM22 ADAMTS16 ADAMTS20 PAPPA	3.60e-04	120	101	5	GO:0004222
GeneOntologyBiologicalProcess	G protein-coupled receptor signaling pathway	OR6B1 GPR25 GALR3 ADGRB2 OR1F12P OR1C1 RXFP3 TAAR8 OR6P1 OR1J2 MET HCAR3 OR6A2 SLIT3 LRP1 OR1G1 RXFP4 ADGRF3 CX3CR1 ADGRA3	1.19e-05	1395	101	20	GO:0007186
GeneOntologyBiologicalProcess	arabinose metabolic process	OTOGL OTOG	2.37e-05	2	101	2	GO:0019566
GeneOntologyBiologicalProcess	vibrational conductance of sound to the inner ear	OTOGL OTOG	2.37e-05	2	101	2	GO:0055127
GeneOntologyBiologicalProcess	L-arabinose metabolic process	OTOGL OTOG	2.37e-05	2	101	2	GO:0046373
Domain	EGF-like_dom	ZAN ADAM29 LAMC3 ADAM22 NELL1 FBLN1 THBS2 EYS MALRD1 SLIT3 LRP1 OTOG	9.01e-09	249	100	12	IPR000742
Domain	EGF_1	ZAN ADAM29 LAMC3 ITGB7 ADAM22 NELL1 FBLN1 THBS2 EYS MALRD1 SLIT3 LRP1	1.17e-08	255	100	12	PS00022
Domain	EGF-like_CS	ZAN ADAM29 LAMC3 ITGB7 ADAM22 NELL1 FBLN1 THBS2 EYS MALRD1 SLIT3 LRP1	1.52e-08	261	100	12	IPR013032
Domain	EGF_2	ZAN ADAM29 LAMC3 ITGB7 ADAM22 NELL1 FBLN1 THBS2 EYS MALRD1 SLIT3 LRP1	1.80e-08	265	100	12	PS01186
Domain	EGF_3	ZAN ADAM29 ADAM22 NELL1 FBLN1 THBS2 EYS MALRD1 SLIT3 LRP1 OTOG	5.24e-08	235	100	11	PS50026
Domain	FRG2	FRG2 FRG2C FRG2B	1.49e-07	3	100	3	PF15315
Domain	FRG2	FRG2 FRG2C FRG2B	1.49e-07	3	100	3	IPR026245
Domain	EGF	ZAN LAMC3 ADAM22 NELL1 FBLN1 THBS2 EYS MALRD1 SLIT3 LRP1	5.28e-07	235	100	10	SM00181
Domain	HECT	WWP1 AREL1 UBR5 HECTD2	1.24e-05	27	100	4	PF00632
Domain	HECTc	WWP1 AREL1 UBR5 HECTD2	1.24e-05	27	100	4	SM00119
Domain	HECT_dom	WWP1 AREL1 UBR5 HECTD2	1.24e-05	27	100	4	IPR000569
Domain	HECT	WWP1 AREL1 UBR5 HECTD2	1.24e-05	27	100	4	PS50237
Domain	7tm_1	OR6B1 GPR25 GALR3 OR1F12P OR1C1 RXFP3 TAAR8 OR6P1 OR1J2 HCAR3 OR6A2 OR1G1 RXFP4 CX3CR1	1.47e-05	677	100	14	PF00001
Domain	G_PROTEIN_RECEP_F1_1	OR6B1 GPR25 GALR3 OR1F12P OR1C1 RXFP3 TAAR8 OR6P1 OR1J2 HCAR3 OR6A2 OR1G1 RXFP4 CX3CR1	1.67e-05	685	100	14	PS00237
Domain	G_PROTEIN_RECEP_F1_2	OR6B1 GPR25 GALR3 OR1F12P OR1C1 RXFP3 TAAR8 OR6P1 OR1J2 HCAR3 OR6A2 OR1G1 RXFP4 CX3CR1	1.84e-05	691	100	14	PS50262
Domain	GPCR_Rhodpsn	OR6B1 GPR25 GALR3 OR1F12P OR1C1 RXFP3 TAAR8 OR6P1 OR1J2 HCAR3 OR6A2 OR1G1 RXFP4 CX3CR1	1.87e-05	692	100	14	IPR000276
Domain	EGF_CA	NELL1 FBLN1 THBS2 EYS SLIT3 LRP1	4.96e-05	122	100	6	SM00179
Domain	EGF-like_Ca-bd_dom	NELL1 FBLN1 THBS2 EYS SLIT3 LRP1	5.43e-05	124	100	6	IPR001881
Domain	Peptidase_M12B_N	ADAM29 ADAM22 ADAMTS16 ADAMTS20	5.51e-05	39	100	4	IPR002870
Domain	Pep_M12B_propep	ADAM29 ADAM22 ADAMTS16 ADAMTS20	5.51e-05	39	100	4	PF01562
Domain	GPCR_Rhodpsn_7TM	OR6B1 GPR25 GALR3 OR1C1 RXFP3 TAAR8 OR6P1 OR1J2 HCAR3 OR6A2 OR1G1 RXFP4 CX3CR1	5.85e-05	670	100	13	IPR017452
Domain	EGF	ZAN THBS2 EYS MALRD1 SLIT3 LRP1	5.94e-05	126	100	6	PF00008
Domain	DISINTEGRIN_1	ADAM29 ADAM22 ADAMTS16 ADAMTS20	6.10e-05	40	100	4	PS00427
Domain	Reprolysin	ADAM29 ADAM22 ADAMTS16 ADAMTS20	6.10e-05	40	100	4	PF01421
Domain	ADAM_MEPRO	ADAM29 ADAM22 ADAMTS16 ADAMTS20	6.10e-05	40	100	4	PS50215
Domain	DISINTEGRIN_2	ADAM29 ADAM22 ADAMTS16 ADAMTS20	6.10e-05	40	100	4	PS50214
Domain	Peptidase_M12B	ADAM29 ADAM22 ADAMTS16 ADAMTS20	6.10e-05	40	100	4	IPR001590
Domain	Disintegrin_dom	ADAM29 ADAM22 ADAMTS16 ADAMTS20	6.73e-05	41	100	4	IPR001762
Domain	MetalloPept_cat_dom	ADAM29 ADAM22 ADAMTS16 ADAMTS20 PAPPA	7.39e-05	81	100	5	IPR024079
Domain	-	ADAM29 ADAM22 ADAMTS16 ADAMTS20 PAPPA	7.39e-05	81	100	5	3.40.390.10
Domain	VWF_dom	ZAN NELL1 THBS2 OTOG	7.41e-05	42	100	4	IPR001007
Domain	VWC_out	ZAN NELL1 OTOG	1.36e-04	19	100	3	SM00215
Domain	-	NELL1 THBS2 EYS SLIT3 PAPPA	1.57e-04	95	100	5	2.60.120.200
Domain	EGF_Ca-bd_CS	NELL1 FBLN1 EYS SLIT3 LRP1	1.74e-04	97	100	5	IPR018097
Domain	ConA-like_dom	ZAN NELL1 THBS2 EYS MALRD1 SLIT3 PAPPA	1.76e-04	219	100	7	IPR013320
Domain	ZINC_PROTEASE	ADAM29 ADAM22 ADAMTS16 ADAMTS20 PAPPA	1.82e-04	98	100	5	PS00142
Domain	EGF_CA	NELL1 FBLN1 EYS SLIT3 LRP1	1.91e-04	99	100	5	PS01187
Domain	Growth_fac_rcpt_	LAMC3 NELL1 FBLN1 EYS SLIT3 LRP1	1.93e-04	156	100	6	IPR009030
Domain	EGF-type_Asp/Asn_hydroxyl_site	NELL1 FBLN1 EYS SLIT3 LRP1	2.63e-04	106	100	5	IPR000152
Domain	Laminin_G	NELL1 THBS2 EYS SLIT3	2.63e-04	58	100	4	IPR001791
Domain	ATII_rcpt	GPR25 RXFP4	2.81e-04	5	100	2	IPR000248
Domain	TSP_1	ADGRB2 THBS2 ADAMTS16 ADAMTS20	3.62e-04	63	100	4	PF00090
Domain	TSP1	ADGRB2 THBS2 ADAMTS16 ADAMTS20	4.08e-04	65	100	4	SM00209
Domain	TSP1_rpt	ADGRB2 THBS2 ADAMTS16 ADAMTS20	4.08e-04	65	100	4	IPR000884
Domain	TSP1	ADGRB2 THBS2 ADAMTS16 ADAMTS20	4.08e-04	65	100	4	PS50092
Domain	HRM	ADGRB2 ADGRF3 ADGRA3	4.43e-04	28	100	3	PF02793
Domain	LRRCT	SLIT3 CD180 ADGRA3	6.60e-04	32	100	3	PF01463
Domain	GPS	ADGRB2 ADGRF3 ADGRA3	7.90e-04	34	100	3	SM00303
Domain	GPS	ADGRB2 ADGRF3 ADGRA3	8.61e-04	35	100	3	PF01825
Domain	VWFC_1	ZAN NELL1 THBS2	9.35e-04	36	100	3	PS01208
Domain	GPS	ADGRB2 ADGRF3 ADGRA3	9.35e-04	36	100	3	PS50221
Domain	GPS	ADGRB2 ADGRF3 ADGRA3	1.01e-03	37	100	3	IPR000203
Domain	VWC	ZAN NELL1 THBS2	1.10e-03	38	100	3	SM00214
Domain	VWFC_2	ZAN NELL1 THBS2	1.10e-03	38	100	3	PS50184
Domain	EGF_CA	NELL1 FBLN1 THBS2 LRP1	1.17e-03	86	100	4	PF07645
Domain	G_PROTEIN_RECEP_F2_1	ADGRB2 ADGRF3 ADGRA3	1.27e-03	40	100	3	PS00649
Domain	GPCR_2_extracellular_dom	ADGRB2 ADGRF3 ADGRA3	1.27e-03	40	100	3	IPR001879
Domain	Laminin_G_2	NELL1 EYS SLIT3	1.27e-03	40	100	3	PF02210
Domain	G_PROTEIN_RECEP_F2_3	ADGRB2 ADGRF3 ADGRA3	1.27e-03	40	100	3	PS50227
Domain	LamG	NELL1 EYS SLIT3	1.68e-03	44	100	3	SM00282
Domain	EGF_3	NELL1 THBS2	1.81e-03	12	100	2	PF12947
Domain	TIL	ZAN OTOG	1.81e-03	12	100	2	PF01826
Domain	EGF_dom	NELL1 THBS2	1.81e-03	12	100	2	IPR024731
Domain	C8	ZAN OTOG	1.81e-03	12	100	2	PF08742
Domain	ASX_HYDROXYL	NELL1 FBLN1 EYS LRP1	2.05e-03	100	100	4	PS00010
Domain	Unchr_dom_Cys-rich	ZAN OTOG	2.13e-03	13	100	2	IPR014853
Domain	C8	ZAN OTOG	2.13e-03	13	100	2	SM00832
Domain	G_PROTEIN_RECEP_F2_2	ADGRB2 ADGRF3 ADGRA3	2.43e-03	50	100	3	PS00650
Domain	7tm_2	ADGRB2 ADGRF3 ADGRA3	2.43e-03	50	100	3	PF00002
Domain	TIL_dom	ZAN OTOG	2.48e-03	14	100	2	IPR002919
Domain	VWD	ZAN OTOG	3.24e-03	16	100	2	SM00216
Domain	VWF_type-D	ZAN OTOG	3.24e-03	16	100	2	IPR001846
Domain	Disintegrin_CS	ADAM29 ADAM22	3.24e-03	16	100	2	IPR018358
Domain	VWFD	ZAN OTOG	3.24e-03	16	100	2	PS51233
Domain	VWD	ZAN OTOG	3.24e-03	16	100	2	PF00094
Domain	MAM	ZAN MALRD1	3.66e-03	17	100	2	SM00137
Domain	Znf_C2H2	ZFAT ZNF474 ZNF559 DNAJC21 ZNF526 ZNF827 ZNF335 RBAK ZNF324 RNF138 ZNF574	3.84e-03	805	100	11	IPR007087
Domain	GPCR_2_secretin-like	ADGRB2 ADGRF3 ADGRA3	4.09e-03	60	100	3	IPR000832
Domain	GPCR_2-like	ADGRB2 ADGRF3 ADGRA3	4.09e-03	60	100	3	IPR017981
Domain	EGF_extracell	ITGB7 ADAM22 NELL1	4.09e-03	60	100	3	IPR013111
Domain	EGF_2	ITGB7 ADAM22 NELL1	4.09e-03	60	100	3	PF07974
Domain	MAM	ZAN MALRD1	4.11e-03	18	100	2	PF00629
Domain	MAM_dom	ZAN MALRD1	4.11e-03	18	100	2	IPR000998
Domain	MAM_2	ZAN MALRD1	4.11e-03	18	100	2	PS50060
Domain	ADAM_CR	ADAM29 ADAM22	4.11e-03	18	100	2	PF08516
Domain	G_PROTEIN_RECEP_F2_4	ADGRB2 ADGRF3 ADGRA3	4.28e-03	61	100	3	PS50261
Domain	PRAME_family	PRAMEF19 PRAMEF18	4.57e-03	19	100	2	IPR026271
Domain	-	ADAM29 ADAM22	5.06e-03	20	100	2	4.10.70.10
Domain	Olfact_rcpt	OR6B1 OR1F12P OR1C1 OR6P1 OR1J2 OR6A2 OR1G1	5.19e-03	393	100	7	IPR000725
Pathway	WP_GPCRS_CLASS_A_RHODOPSINLIKE	OR6B1 GPR25 GALR3 OR1C1 HCAR3 OR6A2 OR1G1 CX3CR1	4.69e-05	260	71	8	M39397
Pubmed	FRG2, an FSHD candidate gene, is transcriptionally upregulated in differentiating primary myoblast cultures of FSHD patients.	FRG2 FRG2C FRG2B	2.67e-08	3	105	3	15520407
Pubmed	Exploring electrostatic interactions of relaxin family peptide receptor 3 and 4 with ligands using a NanoBiT-based binding assay.	RXFP3 RXFP4	9.03e-06	2	105	2	30684458
Pubmed	RIP2 knockdown inhibits cartilage degradation and oxidative stress in IL-1β-treated chondrocytes via regulating TRAF3 and inhibiting p38 MAPK pathway.	TRAF3 RIPK2	9.03e-06	2	105	2	34587513
Pubmed	Pharmacological characterization of relaxin-3/INSL7 receptors GPCR135 and GPCR142 from different mammalian species.	RXFP3 RXFP4	9.03e-06	2	105	2	15367576
Pubmed	Autophagy Regulatory Genes MET and RIPK2 Play a Prognostic Role in Pancreatic Ductal Adenocarcinoma: A Bioinformatic Analysis Based on GEO and TCGA.	RIPK2 MET	9.03e-06	2	105	2	33204717
Pubmed	Altered Met receptor phosphorylation and LRP1-mediated uptake in cells lacking carbohydrate-dependent lysosomal targeting.	MET LRP1	9.03e-06	2	105	2	28724630
Pubmed	Identification of the domains in RXFP4 (GPCR142) responsible for the high affinity binding and agonistic activity of INSL5 at RXFP4 compared to RXFP3 (GPCR135).	RXFP3 RXFP4	9.03e-06	2	105	2	18582868
Pubmed	Identification and characterization of receptor-interacting protein 2 as a TNFR-associated factor 3 binding partner.	TRAF3 RIPK2	9.03e-06	2	105	2	23333941
Pubmed	Similar phenotypes caused by mutations in OTOG and OTOGL.	OTOGL OTOG	9.03e-06	2	105	2	24378291
Pubmed	Mechanism for insulin-like peptide 5 distinguishing the homologous relaxin family peptide receptor 3 and 4.	RXFP3 RXFP4	9.03e-06	2	105	2	27404393
Pubmed	Intestinal tolerance requires gut homing and expansion of FoxP3+ regulatory T cells in the lamina propria.	ITGB7 CX3CR1	2.70e-05	3	105	2	21333554
Pubmed	RIP2 promotes glioma cell growth by regulating TRAF3 and activating the NF‑κB and p38 signaling pathways.	TRAF3 RIPK2	2.70e-05	3	105	2	29693188
Pubmed	Knockdown of SMYD3 by RNA interference down-regulates c-Met expression and inhibits cells migration and invasion induced by HGF.	MET SMYD3	2.70e-05	3	105	2	19321255
Pubmed	The expansion of the PRAME gene family in Eutheria.	PRAMEF19 PRAMEF18	2.70e-05	3	105	2	21347312
Pubmed	Low density lipoprotein receptor-related protein-1 (LRP1) regulates thrombospondin-2 (TSP2) enhancement of Notch3 signaling.	THBS2 LRP1	2.70e-05	3	105	2	20472562
Pubmed	Genomic analysis of human chromosome 10q and 4q telomeres suggests a common origin.	FRG2 FRG2B	2.70e-05	3	105	2	11829491
Pubmed	LRP1 deficiency in microglia blocks neuro-inflammation in the spinal dorsal horn and neuropathic pain processing.	LRP1 CX3CR1	2.70e-05	3	105	2	30746765
Pubmed	A dual-activity topoisomerase complex regulates mRNA translation and turnover.	USP34 WWP1 ADGRB2 NSD1 LAMC3 BIRC6 TBC1D24 MAPK8IP3 VAC14 RADIL ZNF827 ZNF335 MBD5	2.93e-05	1105	105	13	35748872
Pubmed	MAdCAM-1/α4β7 Integrin-Mediated Lymphocyte/Endothelium Interactions Exacerbate Acute Immune-Mediated Hepatitis in Mice.	ITGB7 CX3CR1	5.40e-05	4	105	2	33316453
Pubmed	DCIS in BRCA1 and BRCA2 mutation carriers: prevalence, phenotype, and expression of oncodrivers C-MET and HER3.	MET BRCA2	5.40e-05	4	105	2	26496879
Pubmed	The anti-inflammatory actions of IL-4 in human monocytes are not mediated by IL-10, RP105 or the kinase activity of RIPK2.	RIPK2 CD180	5.40e-05	4	105	2	22484241
Pubmed	Receptors for relaxin family peptides.	RXFP3 RXFP4	5.40e-05	4	105	2	15956688
Pubmed	Relaxin-3/insulin-like peptide 5 chimeric peptide, a selective ligand for G protein-coupled receptor (GPCR)135 and GPCR142 over leucine-rich repeat-containing G protein-coupled receptor 7.	RXFP3 RXFP4	5.40e-05	4	105	2	15465925
Pubmed	International Union of Pharmacology LVII: recommendations for the nomenclature of receptors for relaxin family peptides.	RXFP3 RXFP4	5.40e-05	4	105	2	16507880
Pubmed	System-Wide Modulation of HECT E3 Ligases with Selective Ubiquitin Variant Probes.	WWP1 AREL1 UBR5	6.61e-05	26	105	3	26949039
Pubmed	O-fucosylation of thrombospondin type 1 repeats restricts epithelial to mesenchymal transition (EMT) and maintains epiblast pluripotency during mouse gastrulation.	ADGRB2 THBS2 ADAMTS16 ADAMTS20	8.08e-05	75	105	4	20637190
Pubmed	Cul3-KLHL20 E3 ubiquitin ligase plays a key role in the arms race between HIV-1 Nef and host SERINC5 restriction.	WWP1 UBR5 RNF138	8.29e-05	28	105	3	35474067
Pubmed	Antagonistic roles of ubiquitin ligase HEI10 and SUMO ligase RNF212 regulate meiotic recombination.	RNF212 MLH3	8.97e-05	5	105	2	24390283
Pubmed	The p90 ribosomal S6 kinase-UBR5 pathway controls Toll-like receptor signaling via miRNA-induced translational inhibition of tumor necrosis factor receptor-associated factor 3.	TRAF3 UBR5	8.97e-05	5	105	2	28559278
Pubmed	Duplication and positive selection among hominin-specific PRAME genes.	PRAMEF19 PRAMEF18	8.97e-05	5	105	2	16159394
Pubmed	Inflammation triggers immediate rather than progressive changes in monocyte differentiation in the small intestine.	ITGB7 CX3CR1	8.97e-05	5	105	2	31324779
Pubmed	The human and mouse repertoire of the adhesion family of G-protein-coupled receptors.	ADGRB2 ADGRF3 ADGRA3	9.23e-05	29	105	3	15203201
Pubmed	Multiple roles of FOXJ3 in spermatogenesis: A lesson from Foxj3 conditional knockout mouse models.	RNF212 TEX15 BRCA2	1.24e-04	32	105	3	27739607
Pubmed	International Union of Basic and Clinical Pharmacology. XCIV. Adhesion G protein-coupled receptors.	ADGRB2 ADGRF3 ADGRA3	1.37e-04	33	105	3	25713288
Pubmed	Retinoic acid receptors are required for skeletal growth, matrix homeostasis and growth plate function in postnatal mouse.	PRAMEF19 NSD1 PRAMEF18	1.63e-04	35	105	3	19389355
Pubmed	The methyltransferase SMYD3 mediates the recruitment of transcriptional cofactors at the myostatin and c-Met genes and regulates skeletal muscle atrophy.	MET SMYD3	2.50e-04	8	105	2	23752591
Pubmed	Proline-rich protein PRR19 functions with cyclin-like CNTD1 to promote meiotic crossing over in mouse.	RNF212 MLH3	2.50e-04	8	105	2	32555348
Pubmed	Aggresomal sequestration and STUB1-mediated ubiquitylation during mammalian proteaphagy of inhibited proteasomes.	BIRC6 UBR5 RNF138	2.62e-04	41	105	3	32723828
Pubmed	Cul3-KLHL20 Ubiquitin Ligase Governs the Turnover of ULK1 and VPS34 Complexes to Control Autophagy Termination.	ZFAT FBLN1 PAPPA	3.94e-04	47	105	3	26687681
Pubmed	A critical role of RICK/RIP2 polyubiquitination in Nod-induced NF-kappaB activation.	RIPK2 TAB3	4.00e-04	10	105	2	18079694
Pubmed	RNF212 is a dosage-sensitive regulator of crossing-over during mammalian meiosis.	RNF212 MLH3	4.00e-04	10	105	2	23396135
Pubmed	Genome-wide mapping for clinically relevant predictors of lamotrigine- and phenytoin-induced hypersensitivity reactions.	NELL1 ADAMTS20	4.88e-04	11	105	2	22379998
Pubmed	Otogelin, otogelin-like, and stereocilin form links connecting outer hair cell stereocilia to each other and the tectorial membrane.	OTOGL OTOG	4.88e-04	11	105	2	31776257
Pubmed	Bacterial inhibition of Fas-mediated killing promotes neuroinvasion and persistence.	MET CX3CR1	4.88e-04	11	105	2	35296858
Pubmed	Deubiquitinase MYSM1 Regulates Innate Immunity through Inactivation of TRAF3 and TRAF6 Complexes.	TRAF3 TAB3	5.84e-04	12	105	2	26474655
Pubmed	Genomewide screening for fusogenic human endogenous retrovirus envelopes identifies syncytin 2, a gene conserved on primate evolution.	ERVFC1 ERVFC1-1	5.84e-04	12	105	2	14557543
Pubmed	An abundance of X-linked genes expressed in spermatogonia.	PRAMEF19 TEX15 PRAMEF18	7.69e-04	59	105	3	11279525
Pubmed	Matrix metalloproteinase-14 mediates formation of bile ducts and hepatic maturation of fetal hepatic progenitor cells.	MET TAT	8.02e-04	14	105	2	26724533
Pubmed	A PWWP Domain of Histone-Lysine N-Methyltransferase NSD2 Binds to Dimethylated Lys-36 of Histone H3 and Regulates NSD2 Function at Chromatin.	NSD1 MBD5	8.02e-04	14	105	2	26912663
Pubmed	Novel genetic loci identified for the pathophysiology of childhood obesity in the Hispanic population.	XDH LINC02912 ITGB7 NELL1 THBS2 RADIL MALRD1 ADAMTS20 SMYD3	8.20e-04	814	105	9	23251661
Pubmed	Transcriptome analysis of mouse stem cells and early embryos.	USP34 PRAMEF19 PRAMEF18 BIRC6 ZNF335 RBAK	8.38e-04	363	105	6	14691545
Pubmed	Long-term potentiation modulates synaptic phosphorylation networks and reshapes the structure of the postsynaptic interactome.	TRAF3 ADGRB2 ADAM22 UBR5 LRP1	1.01e-03	251	105	5	27507650
Pubmed	K63 ubiquitylation triggers proteasomal degradation by seeding branched ubiquitin chains.	WWP1 GTF3C5 UBR5	1.02e-03	65	105	3	29378950
Pubmed	Assembly and structure of Lys33-linked polyubiquitin reveals distinct conformations.	WWP1 AREL1	1.05e-03	16	105	2	25723849
Pubmed	Chromosomal location-dependent nonstochastic onset of odor receptor expression.	OR6B1 OR6A2	1.19e-03	17	105	2	20668191
Pubmed	Complement Targets Newborn Retinal Ganglion Cells for Phagocytic Elimination by Microglia.	LRP1 CX3CR1	1.19e-03	17	105	2	30647151
Pubmed	Differential expression of PRAMEL1, a cancer/testis antigen, during spermatogenesis in the mouse.	PRAMEF19 PRAMEF18	1.19e-03	17	105	2	23565261
Pubmed	Mouse Pramel1 regulates spermatogonial development by inhibiting retinoic acid signaling during spermatogenesis.	PRAMEF19 PRAMEF18	1.19e-03	17	105	2	37781892
Pubmed	Fibulin-1 is required during cardiac ventricular morphogenesis for versican cleavage, suppression of ErbB2 and Erk1/2 activation, and to attenuate trabecular cardiomyocyte proliferation.	FBLN1 ADAMTS20	1.19e-03	17	105	2	22183742
Pubmed	The human olfactory receptor gene family.	OR6B1 OR1F12P OR1C1 OR6P1 OR1J2 OR6A2 OR1G1	1.30e-03	541	105	7	14983052
Pubmed	The promoter of the oocyte-specific gene, Oog1, functions in both male and female meiotic germ cells in transgenic mice.	PRAMEF19 PRAMEF18	1.34e-03	18	105	2	23894331
Pubmed	Pramel15 facilitates zygotic nuclear DNMT1 degradation and DNA demethylation.	PRAMEF19 PRAMEF18	1.34e-03	18	105	2	39181896
Pubmed	A missense in HSF2BP causing primary ovarian insufficiency affects meiotic recombination by its novel interactor C19ORF57/BRME1.	RNF212 BRCA2	1.34e-03	18	105	2	32845237
Pubmed	Oogenesin is a novel mouse protein expressed in oocytes and early cleavage-stage embryos.	PRAMEF19 PRAMEF18	1.34e-03	18	105	2	12890732
Pubmed	Wilms Tumor Predisposition	NSD1 BRCA2	1.34e-03	18	105	2	20301471
Pubmed	Oocyte-specific gene Oog1 suppresses the expression of spermatogenesis-specific genes in oocytes.	PRAMEF19 PRAMEF18	1.34e-03	18	105	2	29731491
Pubmed	Identification of a new expanding family of genes characterized by atypical LRR domains. Localization of a cluster preferentially expressed in oocyte.	PRAMEF19 PRAMEF18	1.34e-03	18	105	2	14675769
Pubmed	Sequential arrival and graded secretion of Sema3F by olfactory neuron axons specify map topography at the bulb.	OR6P1 OR6A2	1.34e-03	18	105	2	20550939
Pubmed	Pramel7 mediates ground-state pluripotency through proteasomal-epigenetic combined pathways.	PRAMEF19 PRAMEF18	1.49e-03	19	105	2	28604677
Pubmed	Presence of three distinct molecular species of Gi protein alpha subunit. Structure of rat cDNAs and human genomic DNAs.	GALR3 RXFP3 RXFP4	1.54e-03	75	105	3	2834384
Pubmed	ADAMTS metalloproteases generate active versican fragments that regulate interdigital web regression.	FBLN1 ADAMTS20	1.66e-03	20	105	2	19922873
Pubmed	Trans-ancestry analysis reveals genetic and nongenetic associations with COVID-19 susceptibility and severity.	MALRD1 RAVER1	1.66e-03	20	105	2	33888907
Pubmed	Preferentially Expressed Antigen in Melanoma (PRAME) and the PRAME Family of Leucine-Rich Repeat Proteins.	PRAMEF19 PRAMEF18	1.66e-03	20	105	2	26694250
Pubmed	Oog1, an oocyte-specific protein, interacts with Ras and Ras-signaling proteins during early embryogenesis.	PRAMEF19 PRAMEF18	1.66e-03	20	105	2	16580637
Pubmed	Pramel7 mediates LIF/STAT3-dependent self-renewal in embryonic stem cells.	PRAMEF19 PRAMEF18	1.66e-03	20	105	2	21425410
Pubmed	Genetic variation within the hypothalamus-pituitary-ovarian axis in women with recurrent miscarriage.	FBLN1 PAPPA	1.66e-03	20	105	2	20716560
Pubmed	Proximity-dependent biotin identification (BioID) reveals a dynamic LSD1-CoREST interactome during embryonic stem cell differentiation.	USP34 BIRC6 GTF3C5 BRCA2 UBR5 LRP1	1.72e-03	418	105	6	34709266
Pubmed	Genome-wide meta-analysis identifies new susceptibility loci for migraine.	NSD1 LRP1 SMYD3	1.73e-03	78	105	3	23793025
Pubmed	The G protein-coupled receptor repertoires of human and mouse.	ADGRB2 RXFP4 ADGRF3	1.79e-03	79	105	3	12679517
Pubmed	Global analysis of genes differentially expressed in branching and non-branching regions of the mouse embryonic lung.	TAB3 PA2G4	1.83e-03	21	105	2	15328023
Pubmed	Nonsyndromic Retinitis Pigmentosa Overview	EYS RP1 ADGRA3	1.92e-03	81	105	3	20301590
Pubmed	Sertoli cell-only phenotype and scRNA-seq define PRAMEF12 as a factor essential for spermatogenesis in mice.	PRAMEF19 PRAMEF18	2.00e-03	22	105	2	31729367
Pubmed	The Grainyhead-like epithelial transactivator Get-1/Grhl3 regulates epidermal terminal differentiation and interacts functionally with LMO4.	PPL SMPD3	2.00e-03	22	105	2	16949565
Pubmed	A missense mutation (R565W) in cirhin (FLJ14728) in North American Indian childhood cirrhosis.	SMPD3 TAT	2.00e-03	22	105	2	12417987
Pubmed	Oogenesis specific genes (Nobox, Oct4, Bmp15, Gdf9, Oogenesin1 and Oogenesin2) are differentially expressed during natural and gonadotropin-induced mouse follicular development.	PRAMEF19 PRAMEF18	2.19e-03	23	105	2	19480014
Pubmed	Characterization of the EGFR interactome reveals associated protein complex networks and intracellular receptor dynamics.	ARFGEF3 VAC14 IPO9 EIF2B5	2.34e-03	183	105	4	23956138
Pubmed	Characterization of the interactome of the human MutL homologues MLH1, PMS1, and PMS2.	IPO9 BRCA2 UBR5	2.36e-03	87	105	3	17148452
Pubmed	Non-EST-based prediction of novel alternatively spliced cassette exons with cell signaling function in Caenorhabditis elegans and human.	LRP1 UTY	2.39e-03	24	105	2	17452356
Pubmed	OTUB1 modulates c-IAP1 stability to regulate signalling pathways.	TRAF3 UBR5	2.39e-03	24	105	2	23524849
Pubmed	A protein-protein interaction network for human inherited ataxias and disorders of Purkinje cell degeneration.	TRIB2 WWP1 PPL NELL1 FBLN1 RADIL RNF138	2.51e-03	608	105	7	16713569
Pubmed	DNA Repair Network Analysis Reveals Shieldin as a Key Regulator of NHEJ and PARP Inhibitor Sensitivity.	USP34 NSD1 GTF3C5 BRCA2 UBR5 ZNF827	2.57e-03	453	105	6	29656893
Pubmed	Incomplete reactivation of Oct4-related genes in mouse embryos cloned from somatic nuclei.	PRAMEF19 PRAMEF18	2.59e-03	25	105	2	12620990
Pubmed	Substrate specificities and identification of putative substrates of ATM kinase family members.	BRCA2 PA2G4	2.59e-03	25	105	2	10608806
Pubmed	MAGE-B4, a binding partner of PRAMEF12, is dispensable for spermatogenesis and male fertility in mice.	PRAMEF19 PRAMEF18	2.59e-03	25	105	2	37451217
Pubmed	SSRI treatment modifies the effects of maternal inflammation on in utero physiology and offspring neurobiology.	UTY CX3CR1	2.59e-03	25	105	2	36343752
Pubmed	Expression profiling in transgenic FVB/N embryonic stem cells overexpressing STAT3.	PRAMEF19 PRAMEF18	2.80e-03	26	105	2	18500982
Pubmed	An approach based on a genome-wide association study reveals candidate loci for narcolepsy.	GALR3 ADGRB2 BRCA2 ADGRA3	2.84e-03	193	105	4	20677014
Cytoband	6q27	THBS2 C6orf118 LINC00574	2.80e-04	55	105	3	6q27
Cytoband	8q21	WWP1 RIPK2	3.37e-04	12	105	2	8q21
Cytoband	Ensembl 112 genes in cytogenetic band chr6q27	THBS2 C6orf118 LINC00574	8.40e-04	80	105	3	chr6q27
GeneFamily	Olfactory receptors, family 1	OR1F12P OR1C1 OR1J2 OR1G1	1.60e-05	40	69	4	147
GeneFamily	Relaxin family peptide receptors	RXFP3 RXFP4	8.57e-05	4	69	2	217
GeneFamily	Olfactory receptors, family 6	OR6B1 OR6P1 OR6A2	9.72e-04	51	69	3	153
GeneFamily	Zinc fingers C2H2-type\|ZF class homeoboxes and pseudogenes	ZFAT ZNF474 ZNF559 ZNF526 ZNF827 ZNF335 RBAK ZNF324 ZNF574	1.57e-03	718	69	9	28
GeneFamily	ADAM metallopeptidases with thrombospondin type 1 motif	ADAMTS16 ADAMTS20	2.35e-03	19	69	2	50
GeneFamily	PWWP domain containing	NSD1 MBD5	3.16e-03	22	69	2	1147
GeneFamily	PRAME family	PRAMEF19 PRAMEF18	3.75e-03	24	69	2	686
GeneFamily	ADAM metallopeptidase domain containing\|CD molecules	ADAM29 ADAM22	4.74e-03	27	69	2	47
GeneFamily	Zinc fingers C2H2-type\|Lysine methyltransferases\|PR/SET domain family	NSD1 SMYD3	7.44e-03	34	69	2	487
Coexpression	NABA_ECM_GLYCOPROTEINS	LAMC3 NELL1 FBLN1 THBS2 OTOGL SLIT3 OTOG	1.07e-05	191	103	7	MM17059
Coexpression	NABA_ECM_GLYCOPROTEINS	LAMC3 NELL1 FBLN1 THBS2 EYS SLIT3 OTOG	1.27e-05	196	103	7	M3008
CoexpressionAtlas	facebase_RNAseq_e14.5_palate_poster_distal_ERK2_WT_2500_K1	LNX2 RIPK2 ADGRB2 CACHD1 ADAM22 ARFGEF3 MET NELL1 THBS2 HECTD2 SLIT3 ADAMTS16 PAPPA CD180 MBD5 MN1 UTY	4.29e-06	1166	87	17	facebase_RNAseq_e14.5_palate_poster_distal_ERK2_WT_2500_K1
CoexpressionAtlas	DevelopingKidney_e15.5_Peripheral blastema_emap-27731_k-means-cluster#3_top-relative-expression-ranked_1000	USP34 TRIB2 WWP1 SOCS4 MCM9 ADAMTS20 FASTKD3 MN1	3.78e-05	307	87	8	gudmap_developingKidney_e15.5_Peripheral blastema_1000_k3
ToppCell	facs-Mammary_Gland-Mammary_Gland-21m-Mesenchymal\|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ITGB7 THBS2 RADIL SLIT3 ADAMTS16 LRP1 RECK	1.36e-07	169	103	7	bb43abad2c049b7f4d307737347290e01b3339a3
ToppCell	facs-Mammary_Gland-Mammary_Gland-21m-Mesenchymal-stromal_cell\|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ITGB7 THBS2 RADIL SLIT3 ADAMTS16 LRP1 RECK	1.36e-07	169	103	7	5f18e3f40a5b1b167903f37516ec8181e889c7c5
ToppCell	facs-Mammary_Gland-Mammary_Gland-21m-Mesenchymal-stromal_cell\|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ITGB7 THBS2 RADIL SLIT3 ADAMTS16 LRP1 RECK	1.36e-07	169	103	7	8bfa2d3bb541d02f55d7c95b8fd156c8403befca
ToppCell	Control-Stromal_mesenchymal-Lung_smooth_muscle-MatrixFB_->_Myofibroblast\|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	RNF212 MET NELL1 FBLN1 SLIT3 LRP1 PAPPA	2.34e-07	183	103	7	7eae9b3b4d1c9b135fa7cff348393d4adec474b4
ToppCell	facs-Lung-nan\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ENPP3 XDH CACHD1 FBLN1 SLIT3 LRP1 RECK	3.72e-07	196	103	7	b05f77f3990b662682ffeaf0e4c2fb190e0a6e65
ToppCell	facs-Lung-nan-3m\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ENPP3 XDH CACHD1 FBLN1 SLIT3 LRP1 RECK	3.72e-07	196	103	7	787c6cd92035e0b1108c2c086c42a229016e476b
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic-thymocyte\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ZAN ARFGEF3 OTOGL ADAMTS16 ADAMTS20 OTOG	4.44e-06	184	103	6	2cbed6462fea2622871bb7e49b0df3d984239281
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ZAN ARFGEF3 OTOGL ADAMTS16 ADAMTS20 OTOG	4.44e-06	184	103	6	ea7a7e2bac46d4d2c31a5d576b38a032b5335062
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic-proliferating_thymocyte;_DN_to_DP_transition,_dividing_(some_are_Cd8+/_Cd4+,_some_undergoing_VDJ_recombination)\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ZAN ARFGEF3 OTOGL ADAMTS16 ADAMTS20 OTOG	4.44e-06	184	103	6	2b19a8c5f823e00812908b23e66bb4e563278aff
ToppCell	COPD-Epithelial-Club\|World / Disease state, Lineage and Cell class	LNX2 PPL ARFGEF3 MET RP1 ADGRA3	4.72e-06	186	103	6	3006f4ab1eaf1eb34c10ca9f7c869603d2d25744
ToppCell	Control-Fibroblasts-Adventitial_FB\|Control / group, cell type (main and fine annotations)	FBLN1 THBS2 SLIT3 LRP1 PAPPA MN1	5.02e-06	188	103	6	706a26c372add839d947749f0521a0e1f5c9b0ec
ToppCell	LPS_only-Stromal_mesenchymal-Matrix_Fibroblast-MatrixFB\|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	SLC16A12 NELL1 FBLN1 SLIT3 LRP1 PAPPA	5.17e-06	189	103	6	2a22b9fae70afb3dab8476f9c00e48a4df756410
ToppCell	Adult-Mesenchymal-matrix_fibroblast_2_cell-D175\|Adult / Lineage, Cell type, age group and donor	FBLN1 THBS2 SLIT3 ADAMTS16 PAPPA MN1	5.33e-06	190	103	6	7dcca3469f3a3b70db0420cb94f7765f39492f06
ToppCell	LPS-IL1RA-Stromal_mesenchymal-Matrix_Fibroblast-Activated_MatrixFB\|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	NELL1 FBLN1 THBS2 SLIT3 LRP1 PAPPA	5.33e-06	190	103	6	45df8fee00f8949937863159d7aa042e72748d9b
ToppCell	LPS_only-Stromal_mesenchymal-Matrix_Fibroblast-Diff_MatrixFB\|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	NELL1 FBLN1 THBS2 SLIT3 LRP1 PAPPA	5.33e-06	190	103	6	d60395739458d7f47a3350ade751fe3819500320
ToppCell	LPS-IL1RA+antiTNF-Stromal_mesenchymal-Matrix_Fibroblast-Activated_MatrixFB\|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	NELL1 FBLN1 THBS2 SLIT3 LRP1 PAPPA	5.50e-06	191	103	6	b13229bb7f3713a392271aaf5dbae3edd1b9fe5a
ToppCell	facs-Lung-18m-Mesenchymal-fibroblast-adventitial_fibroblast-adventitial_fibroblast_l1\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	ENPP3 FBLN1 THBS2 SLIT3 LRP1 MN1	5.50e-06	191	103	6	2b73fcd592d16cae8ded5e45c8fbf2d9adc8caad
ToppCell	PND07-Mesenchymal-Mesenchymal_structural-Fibroblastic-AF2\|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	FBLN1 THBS2 SLIT3 SNX18 LRP1 PAPPA	5.50e-06	191	103	6	9f478f36a0b895e607e3bb77fa0f9f03cc0f33fc
ToppCell	Children_(3_yrs)-Epithelial\|Children_(3_yrs) / Lineage, Cell type, age group and donor	LNX2 CACHD1 ARFGEF3 MET RP1 SMYD3	5.50e-06	191	103	6	e432c6e1ae82dddf84314ce73d2b7a991630d905
ToppCell	LPS_only-Stromal_mesenchymal\|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	NELL1 FBLN1 THBS2 SLIT3 LRP1 PAPPA	5.66e-06	192	103	6	162d8b5858d150ecbbd1c9bf2b19c6c9cd50a158
ToppCell	LPS-IL1RA-Stromal_mesenchymal\|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	NELL1 FBLN1 THBS2 SLIT3 LRP1 PAPPA	5.66e-06	192	103	6	4e47a02007f562f29ba5910df64d32a0167d0bd1
ToppCell	Children_(3_yrs)-Mesenchymal-matrix_fibroblast_2_cell-D046\|Children_(3_yrs) / Lineage, Cell type, age group and donor	FBLN1 THBS2 SLIT3 ADAMTS16 PAPPA MN1	5.66e-06	192	103	6	e0f4e4470a71bfa81d9dcd8594e5f82aafc24f81
ToppCell	LPS_only-Stromal_mesenchymal-Matrix_Fibroblast\|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	NELL1 FBLN1 THBS2 SLIT3 LRP1 PAPPA	5.66e-06	192	103	6	ee085e04d5dcfb657522484ed20b8c1ddeccfe0c
ToppCell	facs-Lung-18m-Mesenchymal-fibroblast-adventitial_fibroblast\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	ENPP3 FBLN1 THBS2 SLIT3 LRP1 MN1	5.66e-06	192	103	6	011634a24b0c61d9b463fe755502edbc5cd70b7a
ToppCell	Children_(3_yrs)-Mesenchymal-matrix_fibroblast_2_cell-D139\|Children_(3_yrs) / Lineage, Cell type, age group and donor	SLC16A12 FBLN1 THBS2 SLIT3 PAPPA MN1	5.83e-06	193	103	6	261cafc167c86ab277be4ea7f08b0173e2dde26e
ToppCell	COVID-19-kidney-Fibroblast-2\|COVID-19 / Disease (COVID-19 only), tissue and cell type	TRIB2 LAMC3 OR1J2 THBS2 SLIT3 PAPPA	6.19e-06	195	103	6	3d62ce1c696f47d4d7eb0c5bb0eec2c24b122bb2
ToppCell	Tracheal-NucSeq\|Tracheal / Cell types per location group and 10X technology with lineage, and cell group designations	USP34 BIRC6 UBR5 MBD5 UTY SMYD3	6.95e-06	199	103	6	94b94b17ca18b8dc27b91da1f2ccf89e03cc7035
ToppCell	Bronchial-NucSeq-Stromal-Fibroblastic-Fibro_adventitial\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	FBLN1 THBS2 SLIT3 LRP1 PAPPA MN1	7.15e-06	200	103	6	ad3fdcef895400f929f2ae12ff9bd85fd46adb3a
ToppCell	Parenchymal-NucSeq-Stromal-Fibroblastic-Fibro_adventitial\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	FBLN1 THBS2 SLIT3 LRP1 PAPPA MN1	7.15e-06	200	103	6	74e74123ea7bf38d337a3a0248a6a51437c6ab42
ToppCell	renal_papilla_nuclei-Adult_normal_reference-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Cortical_Thick_Ascending_Limb_Cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	XDH NELL1 OTOGL ADAMTS16 RP1	3.43e-05	159	103	5	c186bf05c61fac348cf41973827cced83fafd58a
ToppCell	wk_15-18-Epithelial-Airway_epithelial_progenitor-epi-prox-progenitor_intermediate_\|wk_15-18 / Celltypes from embryonic and fetal-stage human lung	XDH PPL ARFGEF3 MET RP1	4.09e-05	165	103	5	f6887c64af0f26e33316bc5587487e24d76ece2a
ToppCell	droplet-Marrow-BM-1m-Myeloid-basophil\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ENPP3 ITGB7 MET LRP1 CX3CR1	4.46e-05	168	103	5	2e88d9cb7c80a4656fab290db8b45a5a0599d769
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	TEX15 FBLN1 THBS2 RADIL LRP1	4.85e-05	171	103	5	5d31fc9b60329d4ae3c77e4ca679359d9314397d
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Medullary_Thick_Ascending_Limb_Cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	RNF212 SLC16A12 ARFGEF3 NELL1 RP1	4.98e-05	172	103	5	1565f38266891c3acf49778838de134c5dee5460
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Medullary_Thick_Ascending_Limb_Cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	RNF212 SLC16A12 NELL1 MALRD1 RP1	5.41e-05	175	103	5	e5467dacf81f1f913b1719931cf1a7331434a7e7
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast-Adaptive_/_Maladaptive_/_Repairing_Fibroblast\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	TEX15 FBLN1 THBS2 SLIT3 LRP1	5.41e-05	175	103	5	795a6564d5a75ffd35d39f5274b9e8d28708bbc8
ToppCell	droplet-Mammary_Gland-nan-21m-Endothelial-basal_cell\|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PPL TBC1D24 MLH3 HECTD2 ADAMTS20	5.56e-05	176	103	5	27e5115fae5f0f63b333bc99fbf6a6d4c9182c46
ToppCell	LPS-IL1RA+antiTNF\|World / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	FBLN1 SLIT3 ADAMTS16 MBD5 UTY	5.71e-05	177	103	5	b7fee75de7e96924af488a5baa2334711889ae7c
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Medullary_Thick_Ascending_Limb_Cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	ARFGEF3 NELL1 MALRD1 RP1 FRG2C	5.86e-05	178	103	5	4df6218b20c2f076c22346d23260964cc0d73e65
ToppCell	COVID-19-kidney-Epi_(Mes)\|COVID-19 / Disease (COVID-19 only), tissue and cell type	SLC16A12 MET SLIT3 ADAMTS16 FRG2B	5.86e-05	178	103	5	544379f5a6145429762258d426b876bb36c112f5
ToppCell	Control-Stromal_mesenchymal-Matrix_Fibroblast-MatrixFB\|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	ADAM22 NELL1 FBLN1 SLIT3 LRP1	6.18e-05	180	103	5	08ae0f5d95c45feba68ad99788f7af7ff4c979af
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Distal_tubule_epithelial_cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	SLC16A12 ARFGEF3 NELL1 MALRD1 RP1	6.18e-05	180	103	5	eee71184ebed2694d3e60f579a44b3cf7dd2cd35
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	SLC16A12 ARFGEF3 NELL1 MALRD1 RP1	6.18e-05	180	103	5	a17dbe03597b81e7a1fe2bf2d23e59e55c615a2a
ToppCell	Control-Stromal_mesenchymal-Matrix_Fibroblast-Diff_MatrixFB\|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	SLC16A12 NELL1 FBLN1 SLIT3 LRP1	6.34e-05	181	103	5	9e7d0f1afb8d9bc5a209ddb5314df3a25a0274d9
ToppCell	kidney_cells-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-Collagen+matrisome-high_fibroblast-\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	LAMC3 FBLN1 THBS2 SLIT3 LRP1	6.34e-05	181	103	5	c6d2a13df3b74fade3b0c71e285b4c14c8e52413
ToppCell	COPD-Epithelial-Basal\|World / Disease state, Lineage and Cell class	LNX2 CACHD1 PPL MET ADGRA3	6.34e-05	181	103	5	6d8a886b4afe729f8a05b9c0f4ea9375de735da4
ToppCell	kidney_cells-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-Collagen+matrisome-high_fibroblast\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	LAMC3 FBLN1 THBS2 SLIT3 LRP1	6.34e-05	181	103	5	c62b0a2422377ffadaab63edd538e87a06fa5017
ToppCell	renal_medulla_nuclei-CKD+DKD_normotensive-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Medullary_Thick_Ascending_Limb_Cell\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	SLC16A12 ARFGEF3 NELL1 MALRD1 RP1	6.51e-05	182	103	5	041bc819e6cf2618bf86bce8dfe2df673f392ba3
ToppCell	Primary_Visual_cortex_(V1C)-Neuronal-Glutamatergic_Excit-Glut_E_(THEMIS)-Glut_D_(IT_RORB_THEMIS_LINC00507)_6\|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	OR1J2 NELL1 OTOGL SLIT3 ADAMTS16	6.86e-05	184	103	5	ca35a3d2b536c8b2bf5c4d635605e5a3ae94a428
ToppCell	droplet-Mammary_Gland-nan-18m-Mesenchymal-nan\|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	LAMC3 FBLN1 THBS2 SLIT3 LRP1	6.86e-05	184	103	5	fe4d3def3da4ffdea5ae6bb059f5397efd58fef3
ToppCell	E17.5-Mesenchymal-mesenchymal_fibroblast-mesenchymal_alveolar_niche_cell\|E17.5 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	FBLN1 THBS2 SLIT3 LRP1 MN1	7.04e-05	185	103	5	c85bba1210f1d389add3e40be9b96abac40cf8c1
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Medullary_Thick_Ascending_Limb_Cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	RNF212 SLC16A12 ARFGEF3 NELL1 RP1	7.04e-05	185	103	5	03f64a7132b13a01ba47187e0e15c13ac88f7cb2
ToppCell	Control-Epithelial-Club\|World / Disease state, Lineage and Cell class	LNX2 CACHD1 ARFGEF3 MET ADGRA3	7.22e-05	186	103	5	9798428691408e17ff2af2fe2d1b345f074d67e4
ToppCell	renal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Distal_tubule_epithelial_cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	SLC16A12 ARFGEF3 NELL1 MALRD1 RP1	7.40e-05	187	103	5	85e58a312fc325e4063a2d250666b99b8f99beb6
ToppCell	renal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	SLC16A12 ARFGEF3 NELL1 MALRD1 RP1	7.40e-05	187	103	5	52b5b38bef3cc06487cf42c6fb22fb33f0c7ce2b
ToppCell	droplet-Lung-18m-Mesenchymal-myofibroblast-myofibroblast_cell-pulmonary_interstitial_myofibroblast\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	ENPP3 PPL THBS2 ZNF827 MN1	7.40e-05	187	103	5	8bd635abdee5d5a12a3f7bf74eab4282e8e40741
ToppCell	droplet-Lung-18m-Mesenchymal-myofibroblast-myofibroblast_cell\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	ENPP3 PPL THBS2 ZNF827 MN1	7.40e-05	187	103	5	3cb8cd7f7a4306ff74d1f7f9964014008ec1c6a0
ToppCell	systemic_lupus_erythematosus-flare-Myeloid-non-classical_monocyte-male\|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex	HCAR3 MIDN SNX18 UTY CX3CR1	7.59e-05	188	103	5	3e94d105ca96ceb5fdcca39a8050217913bc02da
ToppCell	Smart-start-Cell-Wel_seq-Neoplastic-Stem-like-OPC-like-OPC-like_Prolif-E\|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	TEX15 FBLN1 C6orf118 ZNF827 ADGRF3	7.59e-05	188	103	5	0476d7ee3e0ce78c3c5b111e9ade01098f9ea7ec
ToppCell	LPS-IL1RA-Stromal_mesenchymal-Matrix_Fibroblast-Diff_MatrixFB\|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	NELL1 FBLN1 THBS2 SLIT3 LRP1	7.78e-05	189	103	5	e9d5e858e320c6e9913c1ea6a54967d21eda605f
ToppCell	5'-Parenchyma_lung-Mesenchymal-Fibroblastic-fibroblastic_type_1-Adventitial_fibroblasts-Adventitial_fibroblasts_L.2.1.2.1\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	FBLN1 THBS2 SLIT3 ADAMTS16 LRP1	7.78e-05	189	103	5	d531399749409d614adca13d181830c6e3287508
ToppCell	droplet-Mammary_Gland-nan-21m-Mesenchymal-stromal_cell\|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FBLN1 THBS2 SLIT3 LRP1 SMPD3	7.78e-05	189	103	5	bc54ffd7bd1627a36747a80ce5139e4a69928400
ToppCell	droplet-Mammary_Gland-nan-21m-Mesenchymal-stromal_cell\|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FBLN1 THBS2 SLIT3 LRP1 SMPD3	7.98e-05	190	103	5	f3ca94a31a35eed5fecf3c4b8c957e1bc4150158
ToppCell	droplet-Mammary_Gland-nan-21m-Mesenchymal\|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FBLN1 THBS2 SLIT3 LRP1 SMPD3	7.98e-05	190	103	5	c2cd1eb674162ee40502c3380b7245c85079c7ce
ToppCell	PCW_10-12-Mesenchymal-Mesenchymal_fibroblastic-mes_adventitial_fibro_(10)\|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung	FBLN1 THBS2 ADAMTS16 PAPPA MN1	7.98e-05	190	103	5	4f775ee24b14733f06ae40b45f2dc1a0f0df0705
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Degenerative_Medullary_Thick_Ascending_Limb_Cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	ARFGEF3 NELL1 MALRD1 RP1 FRG2C	8.18e-05	191	103	5	f631749ef1f2270133664cf5eb4cf545a8482bd3
ToppCell	COPD-Epithelial-Club\|COPD / Disease state, Lineage and Cell class	PPL ARFGEF3 MET RP1 ADGRA3	8.18e-05	191	103	5	c909cf5fa0e6519aa93a47d2c3fcd2ae2163cd8d
ToppCell	droplet-Lung-18m-Mesenchymal-fibroblast-adventitial_fibroblast-adventitial_fibroblast_l17\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	FBLN1 THBS2 PAPPA SMPD3 MN1	8.18e-05	191	103	5	b51e0f5d1b93f526160c904e9091313a5364f3a7
ToppCell	facs-Aorta-Heart-3m-Mesenchymal-fibroblast\|Aorta / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ADGRB2 FBLN1 THBS2 LRP1 SMPD3	8.18e-05	191	103	5	9214655dca96d766737c9f30b624d7fe7050342e
ToppCell	Control-Stromal_mesenchymal\|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	NELL1 FBLN1 SLIT3 LRP1 PAPPA	8.18e-05	191	103	5	14057205ddb9b4bbc582d1358d13cf36d979a61b
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-Collagen+matrisome-high_fibroblast\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	LAMC3 FBLN1 THBS2 SLIT3 LRP1	8.18e-05	191	103	5	39092a0aff8097617820c59f5fea9ee2bb4f63a2
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-Collagen+matrisome-high_fibroblast-\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	LAMC3 FBLN1 THBS2 SLIT3 LRP1	8.18e-05	191	103	5	ee5f1b1c59029c46cbb1a00935c03b9317bb9da9
ToppCell	Fetal_29-31_weeks-Mesenchymal-matrix_fibroblast_2_cell\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	FBLN1 THBS2 SLIT3 PAPPA MN1	8.38e-05	192	103	5	8d56e360ebc624ca4cd7f0af4f3cc599c244f134
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	LAMC3 FBLN1 THBS2 SLIT3 LRP1	8.38e-05	192	103	5	5105e4b577408b4e1a62d0a44c23c2b830ccad88
ToppCell	facs-Lung-nan-3m-Mesenchymal-Adventitial_Fibroblast\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ENPP3 FBLN1 SLIT3 LRP1 MN1	8.38e-05	192	103	5	a2c31390da4962bda9a936470b0b68fa1f5d47d1
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	LAMC3 FBLN1 THBS2 SLIT3 LRP1	8.38e-05	192	103	5	d3c1ad4667a1e223a83ca0fcd5991a0b96f1199a
ToppCell	LPS-IL1RA-Stromal_mesenchymal-Matrix_Fibroblast\|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	NELL1 FBLN1 SLIT3 LRP1 PAPPA	8.38e-05	192	103	5	f4fc2b0121f879bab2bee99dfb5ff2c3ca1c0e1b
ToppCell	facs-Lung-nan-3m-Mesenchymal-adventitial_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ENPP3 FBLN1 SLIT3 LRP1 MN1	8.38e-05	192	103	5	eeab1cef7c36ae824381952c5b2c982368c379fd
ToppCell	Mesenchymal-matrix_fibroblast_2_cell\|World / Lineage, Cell type, age group and donor	FBLN1 THBS2 SLIT3 PAPPA MN1	8.38e-05	192	103	5	a769158c49d2b208c4224d85e7ae68c85cc372ed
ToppCell	facs-Aorta-Heart-3m-Mesenchymal\|Aorta / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PPL MET FBLN1 THBS2 SMPD3	8.38e-05	192	103	5	0dc1f46e40346ed0b286e53b106a812441575100
ToppCell	droplet-Fat-Mat-18m-Mesenchymal\|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FBLN1 SLIT3 LRP1 PAPPA RECK	8.59e-05	193	103	5	ebd090d7801480b3cee45caac3d30cc991836769
ToppCell	droplet-Fat-Mat-18m-Mesenchymal-Cd34+\|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FBLN1 SLIT3 LRP1 PAPPA RECK	8.59e-05	193	103	5	22c58032e58730715224d7934968ce92d150b0e8
ToppCell	facs-Lung-EPCAM-18m-Mesenchymal-Adventitial_Fibroblast\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FBLN1 THBS2 SLIT3 LRP1 MN1	8.59e-05	193	103	5	92048d2e9e43513e6185e09553be3ee47d7e5207
ToppCell	PCW_07-8.5-Mesenchymal-Mesenchymal_fibroblastic-mes_adventitial_fibro_(10)\|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung	ADGRB2 THBS2 ADAMTS16 PAPPA MN1	8.59e-05	193	103	5	cd45118ced91b10baed3b1068d4673ec99824b86
ToppCell	facs-Lung-nan-3m-Mesenchymal\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ENPP3 FBLN1 SLIT3 LRP1 RECK	8.59e-05	193	103	5	d9c20a092b507c43fcf7ccb04073fecd27d1749c
ToppCell	PCW_13-14-Mesenchymal-Mesenchymal_fibroblastic-mes_adventitial_fibro_(10)\|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung	FBLN1 THBS2 ADAMTS16 PAPPA MN1	8.59e-05	193	103	5	adc9fc94f9ec686a417d08c0b8b7b7ab687afec0
ToppCell	facs-Lung-EPCAM-18m-Mesenchymal-adventitial_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FBLN1 THBS2 SLIT3 LRP1 MN1	8.59e-05	193	103	5	ac088c8f27b5b1888610e461ff45870ca60da886
ToppCell	Children_(3_yrs)-Mesenchymal-matrix_fibroblast_2_cell\|Children_(3_yrs) / Lineage, Cell type, age group and donor	FBLN1 THBS2 SLIT3 PAPPA MN1	8.59e-05	193	103	5	9ab47b360bee1d4f1092c2269e58acebe9584021
ToppCell	PND07-Mesenchymal-Mesenchymal_structural-Fibroblastic-AF2-AF2_mature\|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	FBLN1 THBS2 SLIT3 SNX18 LRP1	8.59e-05	193	103	5	051f61156b0e2e95292b2d8377faf3190b50f264
ToppCell	droplet-Fat-Mat-18m-Mesenchymal-mesenchymal_stem_cell_of_adipose\|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FBLN1 SLIT3 LRP1 PAPPA RECK	8.59e-05	193	103	5	573ad2f848bede1fe20c7b4b352a9242ec294725
ToppCell	3'-Broncho-tracheal-Mesenchymal-Fibroblastic-fibroblastic_type_1-Adventitial_fibroblasts-Adventitial_fibroblasts_L.2.1.0.0\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	FBLN1 THBS2 SLIT3 ADAMTS16 MN1	8.80e-05	194	103	5	35b30bc954750e939f81a9a7498b8bc2ce69a299
ToppCell	LPS-antiTNF-Stromal_mesenchymal-Matrix_Fibroblast-MatrixFB\|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	SLC16A12 NELL1 FBLN1 SLIT3 LRP1	8.80e-05	194	103	5	60622bd2f75bfe4c37f721cb12f03dab33f2f58d
ToppCell	kidney_cells-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	LAMC3 FBLN1 THBS2 SLIT3 LRP1	8.80e-05	194	103	5	02b8102be9414d6964cd71019613edff6d88b893
ToppCell	kidney_cells-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-Degenerative_Fibroblast\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	LAMC3 FBLN1 THBS2 SLIT3 LRP1	8.80e-05	194	103	5	29f83cdd63314fff41258937d70b881a5503bfcc
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	LAMC3 FBLN1 THBS2 SLIT3 LRP1	8.80e-05	194	103	5	e03ba6caed59fa64d4d9b042593469d4a6a3dc10
ToppCell	kidney_cells-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-Degenerative_Fibroblast-Degenerative_Fibroblast_119\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	LAMC3 FBLN1 THBS2 SLIT3 LRP1	8.80e-05	194	103	5	d3db241ea316bbcde6d16618193b474591ad5ce4
ToppCell	LPS-antiTNF-Stromal_mesenchymal-Matrix_Fibroblast-Activated_MatrixFB\|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	NELL1 FBLN1 SLIT3 LRP1 PAPPA	8.80e-05	194	103	5	89b706af2b25991fc2707eb24f49ba6ff3ae01f7
ToppCell	facs-Heart-RA-18m-Mesenchymal-fibroblast_of_cardiac_tissue\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PPL FBLN1 SNX18 LRP1 MN1	9.01e-05	195	103	5	690d6e15d7c863fc8f2d33b1f7bf86f019f415c9
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	LAMC3 FBLN1 THBS2 SLIT3 LRP1	9.01e-05	195	103	5	edd4cd8402af81737b2074f9dce71cc6ab09be7e
ToppCell	facs-Heart-RA-18m-Mesenchymal-fibroblast_of_cardiac_tissue\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PPL FBLN1 SNX18 LRP1 MN1	9.01e-05	195	103	5	5c05e2bcea3d5d7ebe6325f7187ccf83301053d8
Computational	Genes in the cancer module 27.	TRIB2 GALR3 ADGRB2 ITGB7 HCAR3 LRP1 CD180 CX3CR1	9.67e-05	355	45	8	MODULE_27
Computational	Metal / Ca ion binding.	NELL1 FBLN1 THBS2 SLIT3 LRP1	2.21e-04	133	45	5	MODULE_324
Disease	Nonsyndromic Deafness	TBC1D24 MET OTOGL OTOG	1.39e-04	81	95	4	C3711374
Disease	symmetrical dimethylarginine measurement	NELL1 SMYD3	3.64e-04	9	95	2	EFO_0006523
Disease	congenital diaphragmatic hernia (implicated_via_orthology)	SLIT3 LRP1	6.63e-04	12	95	2	DOID:3827 (implicated_via_orthology)
Disease	X-11444 measurement	XDH BIRC6	7.82e-04	13	95	2	EFO_0021237
Disease	xanthine measurement	ADAM22 EYS	7.82e-04	13	95	2	EFO_0010548
Disease	response to cranial radiation therapy, short-term memory	DNAJC21 CACHD1 MALRD1	9.69e-04	60	95	3	EFO_0004335, EFO_0010950
Disease	gestational age	EYS C6orf118 MALRD1 UBR5	1.05e-03	138	95	4	EFO_0005112
Disease	migraine disorder	ZNF474 NSD1 NELL1 LRP1 PAPPA SMYD3	1.06e-03	357	95	6	MONDO_0005277
Disease	methadone dose measurement	TRIB2 TEX15 NELL1	1.07e-03	62	95	3	EFO_0007907
Disease	Major Depressive Disorder	GALR3 XDH NELL1 SLIT3 LRP1	1.15e-03	243	95	5	C1269683
Disease	non-word reading	LAMC3 SLIT3 ADAMTS16	1.33e-03	67	95	3	EFO_0005299
Disease	Benign neoplasm of stomach	MET UBR5	1.35e-03	17	95	2	C0153943
Disease	Neoplasm of uncertain or unknown behavior of stomach	MET UBR5	1.35e-03	17	95	2	C0496905
Disease	Carcinoma in situ of stomach	MET UBR5	1.35e-03	17	95	2	C0154060
Disease	Bone marrow hypocellularity	DNAJC21 BRCA2	1.52e-03	18	95	2	C1855710
Disease	asthma, response to diisocyanate	ZFAT TRIB2 KLKP1 C6orf118 OTOG	1.58e-03	261	95	5	EFO_0006995, MONDO_0004979
Disease	Craniosynostosis	NELL1 MN1	1.88e-03	20	95	2	C0010278
Disease	taurocholate measurement	NELL1 ADGRA3	1.88e-03	20	95	2	EFO_0010538
Disease	pantothenic acid mesurement	C6orf118 RECK	1.88e-03	20	95	2	EFO_0010519
Disease	Stomach Carcinoma	MET UBR5	2.07e-03	21	95	2	C0699791
Disease	portal hypertension (biomarker_via_orthology)	XDH CX3CR1	2.27e-03	22	95	2	DOID:10762 (biomarker_via_orthology)
Disease	response to anticonvulsant	NELL1 C6orf118 ADAMTS20	2.64e-03	85	95	3	GO_0036277
Disease	Neoplasm of the genitourinary tract	MET BRCA2	2.70e-03	24	95	2	cv:C0042065
Disease	Involutional paraphrenia	GALR3 XDH	2.93e-03	25	95	2	C1571983
Disease	Psychosis, Involutional	GALR3 XDH	2.93e-03	25	95	2	C1571984
Disease	Involutional Depression	GALR3 XDH	2.93e-03	25	95	2	C0011574
Disease	breast cancer (implicated_via_orthology)	MET BRCA2	2.93e-03	25	95	2	DOID:1612 (implicated_via_orthology)
Disease	Pancytopenia	DNAJC21 BRCA2	3.17e-03	26	95	2	C0030312

Protein segments in the cluster

Peptide	Gene	Start	Entry
CQCQHLSTFAVLAQP	ADGRB2	906	O60241
VHITILNSNCSPAFC	ADAM29	616	Q9UKF5
ASPTAQCLCQHLTAF	ADGRF3	741	Q8IZF5
NATVAFFLQCISCHP	BIRC6	3761	Q9NR09
AAAQCHANSLPLNST	ADGRA3	1121	Q8IWK6
IATCLAFVNSCANPL	GPR25	291	O00155
HRCLPVASFNFSTCL	ADAM22	666	Q9P0K1
AHLTSPLTAIQDCCT	CACHD1	116	Q5VU97
SVTETVAFSHCCLNP	CX3CR1	276	P49238
LCQISAANFPSLTHL	CD180	336	Q99467
TINLSHNPLDCTCSN	CD180	571	Q99467
HNPLDCTCSNIHFLT	CD180	576	Q99467
HQKPSASLACNTHFC	ADAMTS16	1166	Q8TE57
PSSQVYQCINSCLHL	ADAMTS20	1641	P59510
ALSAVHSPTFCQLAC	RAVER1	241	Q8IY67
SLHICITCHAANPAN	NSD1	1636	Q96L73
YCASISPQLIHCVNN	RECK	186	O95980
CLCIQHSATHFQPGT	RADIL	441	Q96JH8
NASLCLQAAPVLFCA	OVOS1	511	Q6IE37
FPTSISVNNCVCHFS	PA2G4	76	Q9UQ80
SVNNCVCHFSPLKSD	PA2G4	81	Q9UQ80
LSFCAANTIPHVFCD	OR1J2	166	Q8NGS2
HFFCDINSLLPLSCS	OR1F12P	176	Q8NHA8
LVAEQSVHCLPATCF	TAT	396	P17735
LCLHQSLCIPDQSFS	EYS	2941	Q5T1H1
TVCNAHVLCISSIPA	MAPK8IP3	801	Q9UPT6
STGVQNLSHCFLCAA	ERVFC1-1	271	P60608
CSTTFPCSQRCINTH	LRP1	2986	Q07954
NETSTNCLPVAHTCF	HECTD2	731	Q5U5R9
SSSLNPLCFECGQQH	LNX2	16	Q8N448
DCHISICSPQVAQLF	EIF2B5	246	Q13144
IEALSSCQLPFQCAH	MLH3	1381	Q9UHC1
QCSSTLASRFQEHCP	PPL	681	O60437
PALSRCSNLTTFCFH	PRAMEF18	371	Q5VWM3
LCSQPNACSRQSHVS	KLKP1	41	Q107X0
FGSQCSFQCRHPAQL	PAPPA	1306	Q13219
LISCTTCHSEFPSRN	DNAJC21	481	Q5F1R6
TPFPNSCLSALHCVS	SMPD3	6	Q9NY59
PNLNHTCPTCSDFLS	NELL1	221	Q92832
PLATNCSTACAHTNV	ITGB7	661	P26010
HFFCDINPLLSLSCT	OR1G1	176	P47890
VNLHCHNTCSPNQSL	NPC1L1	121	Q9UHC9
HNCLPDFICQNTLGS	FBLN1	271	P23142
LVCASSNSCIPAHQR	MALRD1	1991	Q5VYJ5
HFFCDISPLLNLTCS	OR6P1	176	Q8NGX9
HCSSIQCSTDQPPFQ	FRG2B	11	Q96QU4
HCSSIQCSTDQPPFQ	FRG2C	11	A6NGY1
HCSSIQCSTDQPPFQ	FRG2	11	Q64ET8
SHCLAYANSCLNPLV	GALR3	276	O60755
FTNTCCSHPLSNPAE	IDI1	81	Q13907
NSCLSESPVVLQCTH	BRCA2	136	P51587
ESLDCFCPHLQNSTQ	ENPP3	571	O14638
AVFPCISQLTCHVTD	ARFGEF3	2141	Q5TH69
ACTSPASHQLLLNCQ	LINC00574	6	Q9H8X3
ICTCSPQQFNRLHVF	C6orf118	256	Q5T5N4
HSTLPTAHTCFNQLC	AREL1	781	O15033
FQASHTGCQSPLCSA	C17orf80	421	Q9BSJ5
SNTALPCSANQLHFT	MBD5	726	Q9P267
CQAFPAVAQCTLHTD	IPO9	691	Q96P70
VNLSHCFLCTALSQP	ERVFC1	246	P60507
SLSHNCLSQLPACFA	LRRC30	146	A6NM36
SFCLHSCISLSSPEQ	OTOGL	756	Q3ZCN5
HFFCDLNPLLQLSCS	OR1C1	176	Q15619
HFFCDVSPLLNLSCT	OR6A2	181	O95222
QRGSFQCTLHPCAST	OTOG	971	Q6ZRI0
PFHSAICNSSTNLLL	RP1	1116	P56715
ASQPGSHLQCLSVHC	MN1	1271	Q10571
HACTLARLANFCFTP	MCM9	1051	Q9NXL9
SLAQLRCHAQCSPAS	MIDN	326	Q504T8
RHFQSCSQCLSAPPF	MET	521	P08581
FPVSVCLAHSNSCLN	RXFP3	371	Q9NSD7
FPVTTCLAHSNSCLN	RXFP4	291	Q8TDU9
HFQLALIDCNPCTLS	UTY	186	O14607
CHNPVTTVSLCFLTQ	VAC14	626	Q08AM6
QLHSPTNFLIASLAC	TAAR8	61	Q969N4
SCTFLNHPALNRCEQ	TAB3	691	Q8N5C8
CAPLGSVVSNHLSCQ	SLC16A12	101	Q6ZSM3
PALSRCSNLTTFCFH	PRAMEF19	371	Q5SWL8
LLHSCSLNECHPVNF	FASTKD3	451	Q14CZ7
NGTANVCISFSICHT	HCAR3	171	P49019
CNSNHLFQIVPVTCP	RNF138	176	Q8WVD3
QCFPIKNCSSRHSSG	SOCS4	101	Q8WXH5
NCFSHTNVQPCVITT	SOCS4	186	Q8WXH5
HFFCDISPVLNLSCT	OR6B1	176	O95007
ISLLNHSCDPNCSIV	SMYD3	201	Q9H7B4
RQNLACFLTNPHCGS	C11orf1	16	Q9H5F2
CFLTNPHCGSLVNAD	C11orf1	21	Q9H5F2
STINLLSNPFNCNCH	SLIT3	656	O75094
RTSHCDTFNNQPLCS	TBC1D24	526	Q9ULP9
FQPPHRTSCFSLTNC	RNF212	11	Q495C1
PCAQALQKSCHFALS	LINC02912	21	Q8N9X5
HLSECVNAPSTCSFK	TRAF3	221	Q13114
CCNLFSPNQSELLSH	ZFAT	16	Q9P243
ACPQCGRAFSHSSNL	ZNF324	426	O75467
LAPCFCLSAHSNINQ	TRIB2	101	Q92519
SLVPSSIIAHNCVSC	RBAK	126	Q9NYW8
SQRAAFCDHKTTPCS	RIPK2	401	O43353
QCDVFQHFLTCPSST	SNX18	371	Q96RF0
CSACDQLFLSPHQLQ	ZNF574	311	Q6ZN55
LIFNPHPSTVLSCNC	nan	46	Q6ZSR6
VHFSANACLAPICSL	XDH	66	P47989
ETFQCQLCPFTSSRH	ZNF827	431	Q17R98
QAQLVFCPHCSRIFT	ZNF474	281	Q6S9Z5
ATHPFHCSQCQRSFS	ZNF526	301	Q8TF50
CHPVCANRFSTSSLL	GTF3C5	71	Q9Y5Q8
CCEQSPAFTRQLASH	USP34	2861	Q70CQ2
PNLNLVCATNATYHC	THBS2	701	P35442
FNSNLLAHPDICCIS	TEX15	1976	Q9BXT5
NHVPTSTLVQNSCCS	WWP1	191	Q9H0M0
SLRPHQCSQCSFASK	ZNF335	1071	Q9H4Z2
LPNCNQCETAFSQHL	ZNF559	146	Q9BR84
NILHACVSVCFPTSN	UBR5	921	O95071
SVHNNITCFQSTCKP	ZAN	1896	Q9Y493
FFLTADGTHCQQCPS	LAMC3	1001	Q9Y6N6