Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyBiologicalProcessgonadotrophin-releasing hormone neuronal migration to the hypothalamus

PLXNA3 NDNF PLXNA1

2.51e-067873GO:0021828
GeneOntologyBiologicalProcesshypothalamic tangential migration using cell-axon interactions

PLXNA3 NDNF PLXNA1

2.51e-067873GO:0021856
GeneOntologyBiologicalProcesshypothalamus cell migration

PLXNA3 NDNF PLXNA1

5.98e-069873GO:0021855
GeneOntologyBiologicalProcesshypothalamus gonadotrophin-releasing hormone neuron differentiation

PLXNA3 NDNF PLXNA1

5.98e-069873GO:0021886
GeneOntologyBiologicalProcesshypothalamus gonadotrophin-releasing hormone neuron development

PLXNA3 NDNF PLXNA1

5.98e-069873GO:0021888
GeneOntologyBiologicalProcessolfactory nerve formation

PLXNA3 PLXNA1

1.76e-052872GO:0021628
GeneOntologyBiologicalProcesshypothalamus cell differentiation

PLXNA3 NDNF PLXNA1

2.55e-0514873GO:0021979
GeneOntologyBiologicalProcessolfactory nerve morphogenesis

PLXNA3 PLXNA1

5.26e-053872GO:0021627
Pubmed

Gene conversion-like missense mutations in the human cationic trypsinogen gene and insights into the molecular evolution of the human trypsinogen family.

PRSS3P2 PRSS1 PRSS2

1.62e-08389311073713
Pubmed

The origin of trypsin: evidence for multiple gene duplications in trypsins.

PRSS3P2 PRSS1 PRSS2

1.62e-0838939732462
Pubmed

Identifications of novel host cell factors that interact with the receptor-binding domain of the SARS-CoV-2 spike protein.

PRSS3P2 SMG1 PRSS1 PRSS2 RHOBTB3 OSBPL10 SIN3A GAPDHS METTL16 CLSTN1 PRRC2B

8.72e-07650891138777146
Pubmed

Gene conversion between cationic trypsinogen (PRSS1) and the pseudogene trypsinogen 6 (PRSS3P2) in patients with chronic pancreatitis.

PRSS3P2 PRSS1

6.48e-06289225546417
Pubmed

Molecular pathology and evolutionary and physiological implications of pancreatitis-associated cationic trypsinogen mutations.

PRSS3P2 PRSS1

6.48e-06289211702203
Pubmed

Alcohol Consumption and Cigarette Smoking are Important Modifiers of the Association Between Acute Pancreatitis and the PRSS1-PRSS2 Locus in Men.

PRSS1 PRSS2

6.48e-06289227846138
Pubmed

Interaction between trypsinogen isoforms in genetically determined pancreatitis: mutation E79K in cationic trypsin (PRSS1) causes increased transactivation of anionic trypsinogen (PRSS2).

PRSS1 PRSS2

6.48e-06289214695529
Pubmed

Gene conversion between functional trypsinogen genes PRSS1 and PRSS2 associated with chronic pancreatitis in a six-year-old girl.

PRSS1 PRSS2

6.48e-06289215776435
Pubmed

Pancreatitis-Associated PRSS1-PRSS2 Haplotype Alters T-Cell Receptor Beta (TRB) Repertoire More Strongly Than PRSS1 Expression.

PRSS1 PRSS2

6.48e-06289236191639
Pubmed

Hereditary pancreatitis caused by a double gain-of-function trypsinogen mutation.

PRSS1 PRSS2

6.48e-06289218461367
Pubmed

Role of the Common PRSS1-PRSS2 Haplotype in Alcoholic and Non-Alcoholic Chronic Pancreatitis: Meta- and Re-Analyses.

PRSS1 PRSS2

6.48e-06289233202925
Pubmed

Expression of tumor-associated trypsinogens (TAT-1 and TAT-2) in prostate cancer.

PRSS1 PRSS2

6.48e-06289215651064
Pubmed

Immunoreactive anionic and cationic trypsin in human serum.

PRSS1 PRSS2

6.48e-0628922598466
Pubmed

Pre-diagnostic levels of anionic trypsinogen, cationic trypsinogen, and pancreatic secretory trypsin inhibitor in relation to pancreatic cancer risk.

PRSS1 PRSS2

6.48e-06289220484960
Pubmed

Trypsinogen (PRSS1 and PRSS2) gene dosage correlates with pancreatitis risk across genetic and transgenic studies: a systematic review and re-analysis.

PRSS1 PRSS2

6.48e-06289235089416
Pubmed

Trypsinogen copy number mutations in patients with idiopathic chronic pancreatitis.

PRSS1 PRSS2

6.48e-06289218063422
Pubmed

Autocrine extra-pancreatic trypsin 3 secretion promotes cell proliferation and survival in esophageal adenocarcinoma.

PRSS1 PRSS2

1.94e-05389224146905
Pubmed

Identification of plexin family molecules in mice.

PLXNA3 PLXNA1

1.94e-0538928806646
Pubmed

Trypsin-mediated enzymatic degradation of type II collagen in the human vitreous.

PRSS1 PRSS2

1.94e-05389223882137
Pubmed

Differential expression of plexin-A subfamily members in the mouse nervous system.

PLXNA3 PLXNA1

1.94e-05389211241833
Pubmed

Association of claudin2 and PRSS1-PRSS2 polymorphisms with idiopathic recurrent acute and chronic pancreatitis: A case-control study from India.

PRSS1 PRSS2

1.94e-05389226110235
Pubmed

Divergent roles of SPINK1 and PRSS2 variants in tropical calcific pancreatitis.

PRSS1 PRSS2

1.94e-05389219077465
Pubmed

CD4-binding regions of human immunodeficiency virus envelope glycoprotein gp120 defined by proteolytic digestion.

PRSS1 PRSS2

1.94e-0538921763044
Pubmed

Myeloid translocation gene 16b is a dual A-kinase anchoring protein that interacts selectively with plexins in a phospho-regulated manner.

PLXNA3 PLXNA1

1.94e-05389220138877
Pubmed

Defective binding of SPINK1 variants is an uncommon mechanism for impaired trypsin inhibition in chronic pancreatitis.

PRSS1 PRSS2

3.87e-05489233515547
Pubmed

Chromosome assignment of four plexin A genes (Plxna1, Plxna2, Plxna3, Plxna4) in mouse, rat, Syrian hamster and Chinese hamster.

PLXNA3 PLXNA1

3.87e-05489211306810
Pubmed

Polymorphisms at PRSS1-PRSS2 and CLDN2-MORC4 loci associate with alcoholic and non-alcoholic chronic pancreatitis in a European replication study.

PRSS1 PRSS2

3.87e-05489225253127
Pubmed

Acetylation stabilizes ATP-citrate lyase to promote lipid biosynthesis and tumor growth.

KAT2B UBR4

3.87e-05489223932781
Pubmed

PlexinA polymorphisms mediate the developmental trajectory of human corpus callosum microstructure.

PLXNA3 PLXNA1

3.87e-05489225518740
Pubmed

ESCRT-0 Component Hrs Promotes Macropinocytosis of Kaposi's Sarcoma-Associated Herpesvirus in Human Dermal Microvascular Endothelial Cells.

HGS ACTN4

3.87e-05489226819309
Pubmed

Differential coupling of KLF10 to Sin3-HDAC and PCAF regulates the inducibility of the FOXP3 gene.

KAT2B SIN3A

3.87e-05489224944246
Pubmed

Cloning, characterization and nucleotide sequences of two cDNAs encoding human pancreatic trypsinogens.

PRSS1 PRSS2

3.87e-0548923011602
Pubmed

Determination of cell adhesion sites of neuropilin-1.

PLXNA3 PLXNA1

3.87e-05489210725340
Pubmed

A family of transmembrane proteins with homology to the MET-hepatocyte growth factor receptor.

PLXNA3 PLXNA1

3.87e-0548928570614
Pubmed

Semaphorin 5A inhibits synaptogenesis in early postnatal- and adult-born hippocampal dentate granule cells.

PLXNA3 PLXNA1

6.44e-05589225313870
Pubmed

PRSS1-Related Hereditary Pancreatitis

PRSS1 PRSS2

6.44e-05589222379635
Pubmed

P/CAF-mediated acetylation regulates the function of the basic helix-loop-helix transcription factor TAL1/SCL.

KAT2B SIN3A

6.44e-05589211118214
Pubmed

CART: an Hrs/actinin-4/BERP/myosin V protein complex required for efficient receptor recycling.

HGS ACTN4

6.44e-05589215772161
Pubmed

Simultaneous mutation detection in 90 retinal disease genes in multiple patients using a custom-designed 300-kb retinal resequencing chip.

PCDH15 RP1 GRM6 CFB

7.58e-058789420801516
Pubmed

Cell fate decisions by c-Myc depend on ZBTB5 and p53.

KAT2B SIN3A

9.65e-05689233051058
Pubmed

Autoactivation of mouse trypsinogens is regulated by chymotrypsin C via cleavage of the autolysis loop.

PRSS1 PRSS2

9.65e-05689223814066
Pubmed

Urinary matrix metalloproteinase -8, -9, -14 and their regulators (TRY-1, TRY-2, TATI) in patients with diabetic nephropathy.

PRSS1 PRSS2

9.65e-05689218428024
Pubmed

Evidence for genetic control of microwave-induced augmentation of complement receptor-bearing B lymphocytes.

PGM2 CFB

9.65e-0568926980940
Pubmed

Mitochondrial malate dehydrogenase (Mor-1) in the mouse: linkage to chromosome 5 markers.

PGM2 CFB

9.65e-0568921203052
Pubmed

Expression and function of semaphorin 3A and its receptors in human monocyte-derived macrophages.

PLXNA3 PLXNA1

9.65e-05689219480842
Pubmed

Prediction of the coding sequences of unidentified human genes. XII. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro.

RHOBTB3 ESRRG ENPP4 CLSTN1

1.30e-0410089410048485
Pubmed

Common genetic variants in the CLDN2 and PRSS1-PRSS2 loci alter risk for alcohol-related and sporadic pancreatitis.

PRSS1 PRSS2

1.35e-04789223143602
Pubmed

Semaphorin-6A controls guidance of corticospinal tract axons at multiple choice points.

PLXNA3 PLXNA1

1.35e-04789219063725
Pubmed

A switch from hBrm to Brg1 at IFNγ-activated sequences mediates the activation of human genes.

KAT2B HSF1

1.35e-04789221079652
Pubmed

Increased proximal bifurcation of CA1 pyramidal apical dendrites in sema3A mutant mice.

PLXNA3 PLXNA1

1.35e-04789219655386
Pubmed

Plexin-neuropilin-1 complexes form functional semaphorin-3A receptors.

PLXNA3 PLXNA1

1.35e-04789210520994
Pubmed

Mouse model resources for vision research.

RP1 GRM6 AGTPBP1

1.61e-044189321052544
Pubmed

ATAC and Mediator coactivators form a stable complex and regulate a set of non-coding RNA genes.

KAT2B EIF3L SIN3A PRRC2B

1.69e-0410789420508642
Pubmed

The expression of plexins during mouse embryogenesis.

PLXNA3 PLXNA1

1.79e-04889215661641
Pubmed

Differential requirement of histone acetylase and deacetylase activities for IRF5-mediated proinflammatory cytokine expression.

KAT2B SIN3A

1.79e-04889220935208
Pubmed

Integration of opposing semaphorin guidance cues in cortical axons.

PLXNA3 PLXNA1

1.79e-04889222368082
Pubmed

PlexinA2 and semaphorin signaling during cardiac neural crest development.

PLXNA3 PLXNA1

2.30e-04989211688557
Pubmed

Differential transcriptional regulation of individual TCR V beta segments before gene rearrangement.

PRSS1 PRSS2

2.30e-04989211160223
Pubmed

The role of neuropilins in cell signalling.

PLXNA3 PLXNA1

2.30e-04989219909241
Pubmed

Proteomic analysis reveals Hrs ubiquitin-interacting motif-mediated ubiquitin signaling in multiple cellular processes.

RHOBTB3 ESRRG HGS

2.74e-044989319019082
Pubmed

Human transcription factor protein interaction networks.

TRIM33 SMG1 PRSS1 KAT2B ACTR8 SLF1 UBR4 HGS EIF3L SIN3A RBM34 PRRC2B

2.82e-041429891235140242
Pubmed

Plexin A3 and plexin A4 convey semaphorin signals during facial nerve development.

PLXNA3 PLXNA1

2.88e-041089218804103
Pubmed

A human skeletal muscle interactome centered on proteins involved in muscular dystrophies: LGMD interactome.

SMG1 XIRP2 TAX1BP1 ESRRG TPRKB ACTN4 AGTPBP1

2.93e-0449789723414517
Pubmed

Fine genetic and comparative mapping of the deafness mutation Ames waltzer on mouse chromosome 10.

ANK3 PCDH15

3.51e-04118929653653
Pubmed

Semaphorin-5B Controls Spiral Ganglion Neuron Branch Refinement during Development.

PLXNA3 PLXNA1

3.51e-041189231209173
Pubmed

Microsatellite scan identifies new candidate genes for susceptibility to alcoholic chronic pancreatitis in Japanese patients.

PRSS1 PRSS2

3.51e-041189219096130
Pubmed

Functional loss of semaphorin 3C and/or semaphorin 3D and their epistatic interaction with ret are critical to Hirschsprung disease liability.

PLXNA3 PLXNA1

4.20e-041289225839327
Pubmed

PLXNA1 and PLXNA3 cooperate to pattern the nasal axons that guide gonadotropin-releasing hormone neurons.

PLXNA3 PLXNA1

4.20e-041289231690636
Pubmed

On and off retinal circuit assembly by divergent molecular mechanisms.

PLXNA3 PLXNA1

4.20e-041289224179230
Pubmed

Deletion of Sema3a or plexinA1/plexinA3 causes defects in sensory afferent projections of statoacoustic ganglion neurons.

PLXNA3 PLXNA1

4.20e-041289223991118
Pubmed

Transcriptome profiling reveals expression signatures of cranial neural crest cells arising from different axial levels.

PLXNA3 PLXNA1

4.20e-041289228407732
Pubmed

Transmembrane semaphorin signalling controls laminar stratification in the mammalian retina.

PLXNA3 PLXNA1

4.20e-041289221270798
Pubmed

Functional assembly of accessory optic system circuitry critical for compensatory eye movements.

PLXNA3 PLXNA1

4.96e-041389225959730
Pubmed

Plexins are a large family of receptors for transmembrane, secreted, and GPI-anchored semaphorins in vertebrates.

PLXNA3 PLXNA1

4.96e-041389210520995
Pubmed

Plexin signaling via off-track and rho family GTPases.

PLXNA3 PLXNA1

4.96e-041389211604131
Pubmed

Semaphorin3A, Neuropilin-1, and PlexinA1 are required for lymphatic valve formation.

PLXNA3 PLXNA1

4.96e-041389222723296
Pubmed

Paralog knockout profiling identifies DUSP4 and DUSP6 as a digenic dependence in MAPK pathway-driven cancers.

PLXNA3 PRSS2 KAT2B ACSM3 ADAM30 PRMT3 PLXNA1 CAPN11

5.75e-0473089834857952
Pubmed

Cold/menthol TRPM8 receptors initiate the cold-shock response and protect germ cells from cold-shock-induced oxidation.

GPX5 HSF1

5.78e-041489227317670
Pubmed

A midline switch of receptor processing regulates commissural axon guidance in vertebrates.

PLXNA3 PLXNA1

5.78e-041489220159958
Pubmed

The ubiquitin ligase TRIM25 targets ERG for degradation in prostate cancer.

TRIM33 UBR4

5.78e-041489227626314
Pubmed

A systematic gene-based screen of chr4q22-q32 identifies association of a novel susceptibility gene, DKK2, with the quantitative trait of alcohol dependence symptom counts.

NDST3 NDNF ZGRF1

6.03e-046489320332099
Pubmed

Systematic identification of factors for provirus silencing in embryonic stem cells.

DNAAF10 UBR4 EIF3L SIN3A

6.58e-0415389426365490
Pubmed

Pancreatitis Overview

PRSS1 PRSS2

6.65e-041589224624459
Pubmed

POH1 contributes to hyperactivation of TGF-β signaling and facilitates hepatocellular carcinoma metastasis through deubiquitinating TGF-β receptors and caveolin-1.

PLXNA3 GRAMD2A PRSS1 EIF3L RP1

7.44e-0427789530745168
Pubmed

Allocation of paraventricular and supraoptic neurons requires Sim1 function: a role for a Sim1 downstream gene PlexinC1.

PLXNA3 PLXNA1

7.59e-041689217356169
Pubmed

Expression of the semaphorins Sema 3D and Sema 3F in the developing parathyroid and thymus.

PLXNA3 PLXNA1

7.59e-041689218489001
Pubmed

An investigation into the human serum "interactome".

PRSS3P2 PRSS1 SMPDL3A CFB

8.14e-0416289415174051
Pubmed

Plexin-A3 mediates semaphorin signaling and regulates the development of hippocampal axonal projections.

PLXNA3 PLXNA1

8.59e-041789211683995
Pubmed

Semaphorin signaling facilitates cleft formation in the developing salivary gland.

PLXNA3 PLXNA1

8.59e-041789217626059
Pubmed

Analysis of mammalian proteins involved in chromatin modification reveals new metaphase centromeric proteins and distinct chromosomal distribution patterns.

KAT2B SIN3A

8.59e-041789214519686
Pubmed

Generalist genes analysis of DNA markers associated with mathematical ability and disability reveals shared influence across ages and abilities.

METTL16 IQUB

9.65e-041889220602751
Pubmed

Astrocyte-encoded positional cues maintain sensorimotor circuit integrity.

ANK3 ESRRG

1.19e-032089224776795
Pubmed

TNF-α inhibits glucocorticoid receptor-induced gene expression by reshaping the GR nuclear cofactor profile.

WDR19 SMG1 UBR4 VPS13A ADAM30 RBM34 PRRC2B

1.27e-0363889731182584
Pubmed

Class 5 transmembrane semaphorins control selective Mammalian retinal lamination and function.

PLXNA3 PLXNA1

1.32e-032189221835343
Pubmed

Gene-alcohol interactions identify several novel blood pressure loci including a promising locus near SLC16A9.

KAT2B ESRRG

1.45e-032289224376456
Pubmed

Identification of heat shock factor 1 molecular and cellular targets during embryonic and adult female meiosis.

MSH3 HSF1

1.45e-032289221690297
Pubmed

An Interaction Landscape of Ubiquitin Signaling.

TAX1BP1 UBR4 HGS USP25 ACTN4 AGTPBP1

1.50e-0348189628190767
Pubmed

Chr21 protein-protein interactions: enrichment in proteins involved in intellectual disability, autism, and late-onset Alzheimer's disease.

WDR19 TRIM33 ACTR8 ANK3 RHOBTB3 UBR4 USP25 ACTN4 MSH3 AGTPBP1

1.65e-031285891035914814
Pubmed

Genetic mapping of mouse transient receptor potential (Trrp) genes responsible for capacitative calcium entry channels to chromosomes 3, 7, 9, and X.

TRPC5 GRPR

1.72e-03248929722956
Pubmed

A semaphorin code defines subpopulations of spinal motor neurons during mouse development.

PLXNA3 PLXNA1

1.72e-032489215869472
Cytoband7q34

PRSS3P2 PRSS1 PRSS2 ATP6V0A4

3.10e-041678847q34
GeneFamilyPlexins

PLXNA3 PLXNA1

3.84e-049602683
ToppCelldroplet-Liver-LIVER_HEP-30m-Lymphocytic-B_cell|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

XIRP2 CHST4 PCDH15 TIGD4 GRM6 CYB5R2

1.36e-06178876d3cbdec9d75f076e565baca05ede292cca7758a4
ToppCelldroplet-Liver-LIVER_HEP-30m-Lymphocytic-B_cell|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

XIRP2 CHST4 PCDH15 TIGD4 GRM6 CYB5R2

1.41e-061798764135f9e8cd8494cbc189e5210dded84659643fb8
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell-Outer_Medullary_Collecting_Duct_Principal_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

NDST3 ANK3 RHOBTB3 ESRRG ATP6V0A4 SPAG17

1.50e-06181876aa233b652921848af2257cc3687a7a09c3acfb67
ToppCellTCGA-Brain-Primary_Tumor-Low_Grade_Glioma-Oligoastrocytoma-3|TCGA-Brain / Sample_Type by Project: Shred V9

TRIM33 SYCP2L AGO4 UBR4 PCDH15

6.85e-061358753351e8b9e417397c5fa9f856184ff24ce1a27242
ToppCellTCGA-Brain-Primary_Tumor-Low_Grade_Glioma-Astrocytoma-3|TCGA-Brain / Sample_Type by Project: Shred V9

TRIM33 SYCP2L AGO4 UBR4 PCDH15

1.11e-05149875768877bade04ca0321593b8470b5011ad8270431
ToppCell10x5'-Lung-Lymphocytic_T_CD4-Tnaive/CM_CD4|Lung / Manually curated celltypes from each tissue

ANK3 IQCA1 RP1 SPAG17 IQUB

1.66e-0516287591cc14aec8d580cf97a1929bc1acb00fcbcdb57a
ToppCellAT1-AT2_cells-Cryobiopsy_01|World / lung cells shred on cell class, cell subclass, sample id

NDNF PRSS1 PRSS2 RHOBTB3 CFB

2.21e-051728750be41df5d35d818deb7316ac21c9366eb4b7bfd1
ToppCellfacs-Trachea-nan-18m-Epithelial-ciliated_columnar_cell_of_tracheobronchial_tree|Trachea / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

IQCA1 GALNTL5 RP1 SPAG17 IQUB

2.47e-05176875ed788a5969edfd1199828ca5b0dd34e7f29c4d30
ToppCellsevere-CD8+_T_naive|World / disease stage, cell group and cell class

ANK3 ZGRF1 PANK4 OSBPL10 PGBD2

2.82e-0518187569eeeb7f326e230b07495d557f708fbe3312ac0a
ToppCellPND01-03-samps-Epithelial-Alveolar_epithelial|PND01-03-samps / Age Group, Lineage, Cell class and subclass

GRAMD2A NDNF ANK3 ATP6V0A4 PGM2

3.30e-0518787523fe3cdd6cc9b067086a8392d104186d300298ea
ToppCellCOVID-19-kidney-CD-PC|COVID-19 / Disease (COVID-19 only), tissue and cell type

ANK3 ESRRG ATP6V0A4 SPAG17 IQUB

3.38e-051888758f9996c3f3b27efaaae8960a66af77412de9c7ef
ToppCell3'-Broncho-tracheal-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.3.4|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

PRSS2 ESRRG ATP6V0A4 RP1 SPAG17

3.47e-05189875cd4746ea6ae48a7dd14a2960d38d9445a738cf2c
ToppCellRV-15._Ventricular_Cardiomyocyte_III|RV / Chamber and Cluster_Paper

ANK3 XIRP2 ESRRG ACTN4 DDX60L

3.56e-0519087593c3188dfeb0b2f9889f8ae9b9c1f2f34129c99b
ToppCellfacs-Lung-nan-3m-Epithelial-Ciliated_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

KLHL38 IQCA1 RP1 SPAG17 IQUB

3.56e-05190875e243b5fbb17b9ec3cc90bbe970c1d30b0fd1c2e1
ToppCellfacs-Lung-nan-3m-Epithelial-ciliated_columnar_cell_of_tracheobronchial_tree|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

KLHL38 IQCA1 RP1 SPAG17 IQUB

3.56e-05190875fe844559b95832845d2e8d3ab4b57e3d558bc372
ToppCellNS-moderate-d_0-4|moderate / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

ANK3 IQCA1 RP1 SPAG17 IQUB

3.83e-05193875ea345d34440b25f65358a53dc72831998d1c3620
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

ANK3 ESRRG ATP6V0A4 SPAG17 DNAH14

3.93e-0519487593c68c31e39fa44c1d05d7d4997f4f086da4e738
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Epithelial|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

ANK3 RHOBTB3 ESRRG RP1 DNAH14

4.02e-051958756477e6e7be5bd8eb99119a12ae16334ccddecd43
ToppCellTracheal-10x5prime-Epithelial-Epi_airway_neuro-secretory|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

PRSS2 FBXW12 ESRRG ATP6V0A4 GRPR

4.12e-05196875a4cc02ea41479d24044bd2ca6441f85d683c0ca9
ToppCellControl-Neu_4|Control / 5 Neutrophil clusters in COVID-19 patients

CPNE2 KAT2B EIF3L VPS13A NXPE3

4.12e-05196875b8b7b54ca17a08fa775507bb22b1c7248ada8f40
ToppCellTracheal-10x5prime-Epithelial-Epi_airway_neuro-secretory-Ionocyte_n_Brush|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

PRSS2 FBXW12 ESRRG ATP6V0A4 GRPR

4.12e-0519687550aaca81b593ff71790bb75403b2e4c3ab03a6d2
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Epithelial|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

ANK3 RHOBTB3 ESRRG ATP6V0A4 DNAH14

4.12e-05196875eea66711a16134f86e6c533a5a837ff2e0d7ca7f
ToppCellprimary_visual_cortex-Neuronal-glutamatergic_neuron-L6_IT-L6_IT_VISp_Car3|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

SYCP2L CHST4 GALNTL5 DNAH14

1.38e-041348744ef5f395e321cf04e56560be2502a8aa157682f4
ToppCellSubstantia_nigra-Macroglia-CSF_related|Substantia_nigra / BrainAtlas - Mouse McCarroll V32

IQCA1 RP1 SPAG17 DNAH14

1.46e-0413687447663c5d81c766a333207a44fc5b58b07309ee76
ToppCellSubstantia_nigra-Macroglia-CSF_related-EPENDYMAL-Ependyma.Ccdc153_(Ccdc153)--|Substantia_nigra / BrainAtlas - Mouse McCarroll V32

IQCA1 RP1 SPAG17 DNAH14

1.46e-041368746d2e5b871f4cf8d64e6fe0be666fb3490797c635
ToppCellSubstantia_nigra-Macroglia-CSF_related-EPENDYMAL-Ependyma.Ccdc153_(Ccdc153)|Substantia_nigra / BrainAtlas - Mouse McCarroll V32

IQCA1 RP1 SPAG17 DNAH14

1.46e-04136874fd4269d194c7c11c6ab4383393a01efab05cbace
ToppCellSubstantia_nigra-Macroglia-CSF_related-EPENDYMAL|Substantia_nigra / BrainAtlas - Mouse McCarroll V32

IQCA1 RP1 SPAG17 DNAH14

1.46e-041368743f6cec8d52c84191f7f6e2dd4dc47524dfd5b21b
ToppCellSubstantia_nigra-Macroglia-CSF_related-EPENDYMAL-Ependyma.Ccdc153_(Ccdc153)-|Substantia_nigra / BrainAtlas - Mouse McCarroll V32

IQCA1 RP1 SPAG17 DNAH14

1.46e-0413687467d736096d6b6ddb4722809557f5e987063b8d23
ToppCellEpithelial-B_(AT1-AT2-progenitors)|World / shred on cell class and cell subclass (v4)

GRAMD2A NDNF PRSS1 ANK3

1.92e-041468744511916904c1fac252cb68e871b782207f8137b3
ToppCellFetal_brain-organoid_Tanaka_cellReport-GW08-Neuronal|GW08 / Sample Type, Dataset, Time_group, and Cell type.

ANK3 RBM34 CD200

2.10e-045987374590437b1d9a2a8fe56d79b2e66803528b81298
ToppCellPBMC_fresh-frozen-Mild-Moderate_progression_d12-25-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD4_c08-GZMK-FOS_h|Mild-Moderate_progression_d12-25 / Compartment, severity and other cell annotations on 10x 3' data (130k)

GRAMD2A PCDH15 PRMT3 CHN1

2.47e-0415687414e2f693a75f1075f40cc7b16ee430262a5de016
ToppCellfacs-Trachea-24m-Hematologic-myeloid-granulocyte-granulocyte_l26|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

ST3GAL5 GALNTL5 MSH3 GRM6

2.47e-04156874da5cfa8fa9595613f04ce9511f8b42bad34d995a
ToppCell10x5'v1-week_14-16-Hematopoietic-HSC/MPP_and_pro-LMPP|week_14-16 / cell types per 3 fetal stages;per 3',per 5'

PRSS2 DNAAF10 GAPDHS DNAH14

2.47e-0415687496747447ba7dc2c10079cee44394b19ce60b2f41
ToppCell10x5'v1-week_17-19-Hematopoietic-HSC/MPP_and_pro-HSC/MPP|week_17-19 / cell types per 3 fetal stages;per 3',per 5'

PRSS2 IQCA1 XIRP2 SPAG17

2.79e-04161874aee74a2e7a8acd2950341963f1c04b59c7862183
ToppCellHippocampus-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)-Tac1-Inhibitory_Neuron.Gad1Gad2_Pvalb.Tac1_(Interneuron,_Basket_1)|Hippocampus / BrainAtlas - Mouse McCarroll V32

XIRP2 RP1 GAPDHS

2.80e-046587325d2f56f6cd982a227772f8a3b453cdcc8516a47
ToppCellHippocampus-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)-Tac1-Inhibitory_Neuron.Gad1Gad2_Pvalb.Tac1_(Interneuron,_Basket_1)-|Hippocampus / BrainAtlas - Mouse McCarroll V32

XIRP2 RP1 GAPDHS

2.80e-0465873d7d571be0662967e6d8d934e45f928a2f9e1c06a
ToppCellPND03-Epithelial-Epithelial_Alveolar-Epithelial_Alveolar-AT1/AT2|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

GRAMD2A NDNF ANK3 GAPDHS

2.86e-0416287406f5d6c0bb26fe9d5180bc2ebf2c54bf52e715f3
ToppCellPND03-Epithelial-Epithelial_Alveolar-Epithelial_Alveolar-AT1/AT2-AT1/AT2_mature|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

GRAMD2A NDNF ANK3 GAPDHS

2.86e-04162874d0d9c18a73bc0bf4f38308ef2eee8ae20f6a7918
ToppCell10x5'v1-week_17-19-Hematopoietic-HSC/MPP_and_pro|week_17-19 / cell types per 3 fetal stages;per 3',per 5'

PRSS2 IQCA1 XIRP2 CD200

2.92e-04163874edca1d1a345109dbdeb7ee5464faefab1993fdb2
ToppCellFetal_brain-organoid_Tanaka_cellReport-GW16-Mesenchymal-Cilia-bearing_cell|GW16 / Sample Type, Dataset, Time_group, and Cell type.

DNAAF10 ESRRG PRMT3 METTL16

2.99e-04164874346e1530b4bf30adbcb2f7d64fdfb4cd8df69d7f
ToppCellwk_20-22-Hematologic-Myeloid-HSC/ELP|wk_20-22 / Celltypes from embryonic and fetal-stage human lung

PRSS2 XIRP2 DNAH14 CD200

2.99e-041648743c07d8f53511f269540bf032738a4ada35650b18
ToppCelldroplet-Pancreas-Exocrine-24m-Epithelial-pancreatic_acinar_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PRSS1 PRSS2 ACSM3 ATP6V0A4

3.06e-04165874622aca1d49bd8c917b131e4f4959d9dba411d22b
ToppCellE16.5-Epithelial-Epithelial_Airway-Ciliated/Deuterosomal-Ciliated-Ciliated_mature|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

RP1 GAPDHS SPAG17 IQUB

3.28e-04168874fa7c0303918cea04e3f4c4f3cb079be19004d214
ToppCellE16.5-Epithelial-Epithelial_Airway-Ciliated/Deuterosomal-Ciliated|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

RP1 GAPDHS SPAG17 IQUB

3.28e-041688747edcab103c69e928d5c19a0d218ffb3ae32f9e70
ToppCellFrontal_cortex-Neuronal-Excitatory-eN2(Slc17a7_Slc17a6)-Syt6-Excitatory_Neuron.Slc17a7.Syt6-Bdnf_(Deep_layer_pyramidal_cells)-|Frontal_cortex / BrainAtlas - Mouse McCarroll V32

ACSM3 XIRP2 GAPDHS

3.34e-046987324a480394630385ee51b1dfe1123480107a11403
ToppCellFrontal_cortex-Neuronal-Excitatory-eN2(Slc17a7_Slc17a6)-Syt6-Excitatory_Neuron.Slc17a7.Syt6-Bdnf_(Deep_layer_pyramidal_cells)|Frontal_cortex / BrainAtlas - Mouse McCarroll V32

ACSM3 XIRP2 GAPDHS

3.34e-04698731ab1d92e03a31bb1fe87f055d407a81c4d1d81b8
ToppCellfacs-Pancreas-Exocrine-3m-Epithelial-pancreatic_acinar_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ZYG11A PRSS1 PRSS2 GRPR

3.66e-04173874c62e3ffed55bbb00dcaef6da0aab8446f3f55085
ToppCellfacs-Pancreas-Exocrine-3m-Epithelial-pancreatic_acinar_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ZYG11A PRSS1 PRSS2 GRPR

3.66e-04173874f612d4ea9ab8dcde475f4118bca3e49be786e7fa
ToppCelldroplet-Liver-LIVER_HEPATOCYTES-30m-Lymphocytic-B_cell|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CHST4 ATP6V0A4 CHN1 CD200

3.83e-0417587459249c9e83952d7277010e7be3c779e26399eb5d
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Medullary_Thick_Ascending_Limb_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

RHOBTB3 ESRRG RP1 DNAH14

3.83e-04175874e5467dacf81f1f913b1719931cf1a7331434a7e7
ToppCelldroplet-Liver-LIVER_HEPATOCYTES-30m-Lymphocytic-B_cell|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CHST4 ATP6V0A4 CHN1 CD200

3.83e-04175874b35cc1357495f2a03a6500f807c6e6f8c877734d
ToppCellHippocampus-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)-Tac1|Hippocampus / BrainAtlas - Mouse McCarroll V32

XIRP2 RP1 GAPDHS

4.10e-0474873c652ef04a1b8716b954ce913daa481cc02f4d44e
ToppCell3'-GW_trimst-2-SmallIntestine-Mesenchymal-mesothelial_cell|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

IQCA1 CHST4 CFB CD200

4.17e-04179874056df2aaff750e0e283e7da78fcc3c90c366aac0
ToppCellfacs-Trachea-18m-Epithelial-airway_epithelial-tracheobronchial_ciliated_cell-ciliated_cell|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

IQCA1 RP1 SPAG17 IQUB

4.17e-04179874d4efbc34f52136039b96451fd0b0a0ad164197c6
ToppCellfacs-Trachea-18m-Epithelial-airway_epithelial-tracheobronchial_ciliated_cell|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

IQCA1 RP1 SPAG17 IQUB

4.17e-041798748a66d197a2f55d763ff7ef0bec89ee96f59c3937
ToppCellFetal_29-31_weeks-Epithelial-alveolar_epithelial_cell_type_2/Club-like_(AT2/Club-like)-D150|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

ANK3 ST3GAL5 RP1 CHN1

4.17e-04179874815b959ce8721c5ded70c0ca6e318dafc691746e
ToppCell3'-GW_trimst-2-SmallIntestine-Mesenchymal-mesothelial_cell-Mesothelium|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

IQCA1 CHST4 CFB CD200

4.17e-04179874f5f3945ef3b9efc5921a71fd51deeb2c80f0ce11
ToppCellrenal_papilla_nuclei-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell-Outer_Medullary_Collecting_Duct_Principal_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

ANK3 RHOBTB3 ESRRG IQUB

4.17e-04179874d3438fed0d85d5ed5afa8ff820c45143d77b6c0d
ToppCelldroplet-Liver-LIVER-30m-Lymphocytic-B_cell|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CHST4 ATP6V0A4 VIT CD200

4.26e-041808743d95232b5785c705f41e01e3ffe0fa8dce1ff0a7
ToppCelldroplet-Liver-LIVER-30m-Lymphocytic-B_cell|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CHST4 ATP6V0A4 VIT CD200

4.26e-0418087447e345359064dc8ceec982b062e47802e728b43f
ToppCellsevere-CD8+_T_naive|severe / disease stage, cell group and cell class

ANK3 ZGRF1 PANK4 PGBD2

4.26e-0418087494fe530367b170777f4051a4034cff06d80dbb83
ToppCell10x5'-Liver-Lymphocytic_T_CD4-T_CD4/CD8|Liver / Manually curated celltypes from each tissue

SMG1 ANK3 VPS13A RBM34

4.35e-04181874f2315414e714ac86211546a935660c4be6e85f1b
ToppCellControl-Epithelial_cells-Airway_ciliated|Control / group, cell type (main and fine annotations)

ESRRG RP1 SPAG17 IQUB

4.44e-04182874fb725d10d9ed25dfc6d5bb69cfef78513f7d3e8f
ToppCellCOVID-19-Heart-CM_3|Heart / Disease (COVID-19 only), tissue and cell type

ANK3 XIRP2 ESRRG DDX60L

4.44e-04182874287fcc3897ae08841f6f85ae6c9cef16f75b1dd1
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell-Outer_Medullary_Collecting_Duct_Principal_Cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

ANK3 ATP6V0A4 SPAG17 IQUB

4.53e-04183874b5ede5a0048c585b73c00e88aeddbcaf669347b1
ToppCellPBMC-Control-Myeloid-Neutrophil-immature_Neutrophil|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

CPNE2 VPS13A OSBPL10 NXPE3

4.62e-04184874a8c6028d745aaa6ee7842259238694cb50ce0526
ToppCellPBMC-Control-Myeloid-Neutrophil-immature_Neutrophil-Neu_4|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

CPNE2 VPS13A OSBPL10 NXPE3

4.62e-04184874081d045f3bc98a36f342de7d50f39c9a888dd7eb
ToppCellControl-Myeloid_G-immature_Neutrophil|Control / Disease group, lineage and cell class

CPNE2 VPS13A OSBPL10 NXPE3

4.62e-0418487445f873236f7e90fb78c8e291d3b5b92d121acec9
ToppCellPBMC-Control-Myeloid-Neutrophil-immature_Neutrophil|Control / Location, Disease Group, Cell group, Cell class (2021.03.09)

CPNE2 VPS13A OSBPL10 NXPE3

4.62e-0418487484c20730cd92b9aaa50077d7b625e37e7f9e91d2
ToppCellPBMC-Control-Myeloid-Neutrophil-immature_Neutrophil-Neu_4|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

CPNE2 VPS13A OSBPL10 NXPE3

4.62e-04184874d31d4116d1d196633784863781fa45673607a421
ToppCellLPS-antiTNF-Epithelial_alveolar-AT_2-Differentiating_AT2|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

ANK3 ST3GAL5 ATP6V0A4 OSBPL10

4.62e-04184874ab2f06906fc7a9931dfa0864ef506832b07fb93e
ToppCellPND01-03-samps-Epithelial|PND01-03-samps / Age Group, Lineage, Cell class and subclass

GRAMD2A NDNF ANK3 ATP6V0A4

4.72e-041858742b854df79cfe2cb4d2f9c2938a066e0aa3649325
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Epithelial-Distal_tubule_epithelial_cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

RHOBTB3 ESRRG RP1 DNAH14

4.72e-04185874898a093757f86be3e18d2ef1f16a71f50ef81dc3
ToppCellCOVID-19-Epithelial_cells-Airway_ciliated|COVID-19 / group, cell type (main and fine annotations)

ESRRG RP1 SPAG17 IQUB

4.72e-0418587418a40f0a338aa398d81384b5159fb80ce8a2020c
ToppCellFetal_29-31_weeks-Epithelial-alveolar_epithelial_cell_type_2/Club-like_(AT2/Club-like)|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

ANK3 ST3GAL5 RP1 DNAH14

4.82e-041868742ea5ff14861e5f91d0e6a5767c403a24045d715c
ToppCellNS-critical-d_16-33-Epithelial-Ciliated|d_16-33 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

IQCA1 RP1 SPAG17 IQUB

4.82e-0418687476033438426d8f9c72cd6691a7baf92104c9f03d
ToppCell(5)_Glands_duct|World / Oesophagus cell shreds on cell class (v1) and cell subclass (v1)

RHOBTB3 CHST4 ESRRG CFB

4.82e-04186874ad8d5010e5095508f4995e0c6c016a44e8ffb8dd
ToppCelldroplet-Lung-nan-18m-Epithelial-Ciliated_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

IQCA1 RP1 SPAG17 IQUB

4.82e-04186874740fd06bcd3b24e6ff2ecf8080f378afc3e95084
ToppCellrenal_papilla_nuclei-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

ESRRG OSBPL10 RP1 DNAH14

4.82e-04186874f0c8de4f6ae9047b9108a47a2af8c5f42bc103b0
ToppCelldroplet-Lung-nan-18m-Epithelial-ciliated_columnar_cell_of_tracheobronchial_tree|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

IQCA1 RP1 SPAG17 IQUB

4.82e-041868745ab43a298d23238b34e898d11decf0ad81d1b14e
ToppCellfacs-Lung-EPCAM-3m-Epithelial-Ciliated_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

WDR19 IQCA1 SPAG17 IQUB

4.91e-0418787404dba2ed09ee4180830bdf0191921696697ea234
ToppCellLPS-antiTNF-Epithelial_alveolar|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

GRAMD2A NDNF ANK3 ST3GAL5

4.91e-04187874201ff693e4756ee3e44762885b3a303a77eb535b
ToppCellfacs-Lung-EPCAM-18m-Epithelial-ciliated_columnar_cell_of_tracheobronchial_tree|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

IQCA1 RP1 SPAG17 IQUB

4.91e-04187874051b8c07d7489ce7576f6c57ce7008767ef76869
ToppCellrenal_papilla_nuclei-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell-Degenerative_Descending_Thin_Limb_Cell_Type_3|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

ESRRG OSBPL10 RP1 DNAH14

4.91e-04187874c31130fc2f9f882944b2ba366a034a03f051c4b9
ToppCellfacs-Lung-EPCAM-18m-Epithelial-Ciliated_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

IQCA1 RP1 SPAG17 IQUB

4.91e-04187874888856cde7a69ea2f14d590597e25b1af6383c51
ToppCelldroplet-Lung-3m-Epithelial-airway_epithelial-lung_ciliated_cell-ciliated_cell|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

IQCA1 RP1 SPAG17 IQUB

4.91e-041878741bba994aaaa9825b54aaeaff3829850267bc4602
ToppCellLPS-antiTNF-Epithelial_alveolar-AT_1-Differentiating_AT2|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

GRAMD2A NDNF IQCA1 ST3GAL5

4.91e-0418787458d48128547ee3513d0bf7f78e61b76b1c472ca9
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Cortical_Thick_Ascending_Limb_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

RHOBTB3 ESRRG ATP6V0A4 RP1

4.91e-041878747ea8731288e2a99f45e3958590ee1d76f49ae888
ToppCellfacs-Lung-EPCAM-3m-Epithelial-ciliated_columnar_cell_of_tracheobronchial_tree|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

WDR19 IQCA1 SPAG17 IQUB

4.91e-04187874805dafe22f835ece4dd091d8030d0a63b52a48dd
ToppCelldroplet-Lung-3m-Epithelial-airway_epithelial-lung_ciliated_cell|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

IQCA1 RP1 SPAG17 IQUB

4.91e-04187874d6ac351e7aeba98851d308c14ac395044fe4fbbb
ToppCell5'-GW_trimst-1-SmallIntestine-Epithelial-epithelial_progenitor_cell-Proximal_progenitor|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

PRSS1 XIRP2 RBM34 CFB

4.91e-041878748e7ac5808bb292101e33d70616ae784b951e4bf0
ToppCellEpithelial-ciliated_cell|World / Lineage, Cell type, age group and donor

ESRRG RP1 SPAG17 IQUB

5.01e-0418887461a459f3fe57e5728efc72637ff2edc2d343492b
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Cortical_Thick_Ascending_Limb_Cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

RHOBTB3 ESRRG ATP6V0A4 RP1

5.01e-041888742ee64bc73a2251fd9f374be759b442cf4ed0d19e
ToppCellLPS-IL1RA+antiTNF-Epithelial_alveolar|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

GRAMD2A NDNF ANK3 ST3GAL5

5.01e-0418887443a0508d2524a5b310e89e9422843dcaab999bc3
ToppCellLPS-IL1RA-Epithelial_alveolar-AT_2-Differentiating_AT2|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

NDNF ANK3 ST3GAL5 OSBPL10

5.01e-041888744bdf8d49af0e9da349b16e3f012e1b0eec04cc4f
ToppCellrenal_papilla_nuclei-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

ESRRG OSBPL10 RP1 DNAH14

5.01e-04188874af740fa78542438fdff627ea1f74f4eee43316be
ToppCellAdult-Epithelial-ciliated_cell-D231|Adult / Lineage, Cell type, age group and donor

ESRRG RP1 SPAG17 IQUB

5.01e-0418887434b11f72ca73153d02edcd09b38983ad1a504659
ToppCelldroplet-Lung-18m-Epithelial-airway_epithelial-lung_ciliated_cell-ciliated_cell|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

IQCA1 RP1 SPAG17 IQUB

5.01e-041888740eca3dc93724e23b71e687fc24fa9f1e89bdef6a
ToppCelldroplet-Lung-18m-Epithelial-airway_epithelial-lung_ciliated_cell|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

IQCA1 RP1 SPAG17 IQUB

5.01e-041888749ce3e1fffce87ad19812ecbf9b7f9935a975d676
ToppCellPND01-Epithelial-Epithelial_Airway-Ciliated/Deuterosomal-Ciliated-Ciliated_mature|PND01 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

IQCA1 RP1 SPAG17 IQUB

5.12e-04189874b55de812043b670cbde810d7d42f45909b6d66ef
ComputationalNeighborhood of SERPINI2

PRSS3P2 PRSS1 PRSS2

2.15e-0425513GNF2_SERPINI2
ComputationalNeighborhood of SPINK1

PRSS3P2 PRSS1 PRSS2

2.72e-0427513GNF2_SPINK1
Drug26-nor-25-doxylcholestanol

PRSS1 PRSS2 ANK3

9.00e-0611883CID000125890
Drugverbascose

PRSS1 PRSS2 CHN1

9.00e-0611883CID000441434
Drug2-propylpentanoic acid; Up 200; 1000uM; PC3; HT_HG-U133A

WDR19 ACSM3 ST3GAL5 RHOBTB3 ESRRG VPS13A NXPE3

9.70e-061928871209_UP
Drug2-aminothiophenol

PRSS1 PRSS2 ACSM3

1.97e-0514883CID000008713
DrugS 131

KAT2B ACSM3 CHN1

3.01e-0516883CID005744397
Drugmethyl acetimidate

PRSS1 PRSS2 GAPDHS

3.65e-0517883CID000026888
DrugN-allylglycine

PRSS1 PRSS2

4.42e-053882CID000076651
DrugN-acetyl-L-norvaline methyl ester

PRSS1 PRSS2

4.42e-053882CID000150916
DrugYAKR-CK

PRSS1 PRSS2

4.42e-053882CID005487256
Drugschizopeptin 791

PRSS1 PRSS2

4.42e-053882CID000636821
Drug2 alpha-bromoacetoxyprogesterone

PRSS1 PRSS2

4.42e-053882CID000135256
DrugLapg-nh2

PRSS1 PRSS2

4.42e-053882CID003082486
DrugMethotrexate-polylysine

PRSS1 PRSS2

4.42e-053882CID000163214
Drugmethyl octanesulfonate

PRSS1 PRSS2

4.42e-053882CID000165858
Drug3HFGB

PRSS1 PRSS2

4.42e-053882CID000126268
Drug4-chlorobenzenediazonium hexafluorophosphate

PRSS1 PRSS2

4.42e-053882CID002723983
Drugmethyl lignocerate

PRSS1 PRSS2

4.42e-053882CID000075546
Drug10-(carboxyethyl)flavin

PRSS1 PRSS2

4.42e-053882CID003082170
DrugZ-Lys-CH2Cl

PRSS1 PRSS2

4.42e-053882CID000127335
Drug2,6-dimethyl-3-pyridinol

PRSS1 PRSS2

4.42e-053882CID000070732
DrugN-phosphopyridoxyl-L-serine

PRSS1 PRSS2

4.42e-053882CID000195946
DrugZ-Arg-OH

PRSS1 PRSS2

4.42e-053882CID000071055
DrugGB-107

PRSS1 PRSS2

4.42e-053882CID000056813
Drugp-amidinophenylpyruvate

PRSS1 PRSS2

4.42e-053882CID000444106
Drugv 1194

PRSS1 PRSS2

4.42e-053882CID000074702
Drugmitorubrinic acid

PRSS1 PRSS2

4.42e-053882CID000379537
DrugASA-PE

PRSS1 PRSS2

4.42e-053882CID003037809
DrugL-TAPA

PRSS1 PRSS2

4.42e-053882CID000193734
Drugb-Ti

PRSS1 PRSS2 CFB

5.17e-0519883CID011840927
DrugAC1LAOUV

PRSS1 PRSS2

8.82e-054882CID000492408
Drug5'-S-propynyl-5'-thioadenosine

PRSS1 PRSS2

8.82e-054882CID000492409
Drug4-Amino-3-nitrobenzoic acid

PRSS1 PRSS2

8.82e-054882CID000074115
Drug4-ethylpiperidine

PRSS1 PRSS2

8.82e-054882CID000076704
Drugtorquatone

PRSS1 PRSS2

8.82e-054882CID000256516
DrugAC1Q5JO7

PRSS1 PRSS2

8.82e-054882CID000128324
DrugDsdgk

PRSS1 PRSS2

8.82e-054882CID000130454
DrugmGBSOM

PRSS1 PRSS2

8.82e-054882CID003080804
DrugBa-O

PRSS1 PRSS2

8.82e-054882CID000002280
DrugNSC-45351

PRSS1 PRSS2

8.82e-054882CID000018046
Drugindomethacin-NHS

PRSS1 PRSS2

8.82e-054882CID000128571
Drugbromomesaconic acid

PRSS1 PRSS2

8.82e-054882CID006449799
DrugN-carbobenzoxyglycine vinyl ester

PRSS1 PRSS2

8.82e-054882CID000047309
DrugNSC-13568

PRSS1 PRSS2

8.82e-054882CID000224783
Drugxylaric acid

PRSS1 PRSS2

8.82e-054882CID003084064
DrugFAH2

PRSS1 PRSS2 TRPC5 MSH3

1.11e-0464884CID000000661
DrugMerbromin [129-16-8]; Up 200; 5uM; MCF7; HT_HG-U133A

AGO4 SIGLEC6 ATP6V0A4 ENPP4 GRPR PLXNA1

1.14e-041968864722_UP
Drug2-propylpentanoic acid; Up 200; 50uM; PC3; HT_HG-U133A

ORC4 AGO4 SIGLEC6 ESRRG PLXNA1 MX2

1.20e-041988861222_UP
DrugAzathioprine [446-86-6]; Up 200; 14.4uM; PC3; HG-U133A

ORC4 TAX1BP1 MSH3 AGTPBP1 PRRC2B DOP1A

1.20e-041988861945_UP
DrugSr 42128

PRSS1 PRSS2

1.47e-045882CID005487043
Drug4-TGPAP

PRSS1 PRSS2

1.47e-045882CID000132086
DrugPTA-Arg

PRSS1 PRSS2

1.47e-045882CID000194378
DrugI 333

PRSS1 PRSS2

1.47e-045882CID000533915
DrugN-(5'-carboxypentyl)-1-deoxynojirimycin

PRSS1 PRSS2

1.47e-045882CID000133177
DrugPTA-GPA

PRSS1 PRSS2

1.47e-045882CID000139330
Drugpropynyl benzoate

PRSS1 PRSS2

1.47e-045882CID000196666
DrugM 93

PRSS1 PRSS2

1.47e-045882CID006444952
Drug6-amidinoindole

PRSS1 PRSS2

1.47e-045882CID003018291
DrugAg-B

PRSS1 PRSS2

1.47e-045882CID000004286
Drugbeta-Neuroprotectin

PRSS1 PRSS2

1.47e-045882CID005748443
Drug2,6-diphenoxypyridine

PRSS1 PRSS2

1.47e-045882CID000824772
DrugAC1L3UIZ

PRSS1 PRSS2

1.47e-045882CID000147121
DrugIle-Phe-Lys-CH2Cl

PRSS1 PRSS2

1.47e-045882CID000124393
Drugrho-guanidinobenzoate

PRSS1 PRSS2

1.47e-045882CID005311472
DrugMeebdp

PRSS1 PRSS2

1.47e-045882CID000132560
DrugTl-I

PRSS1 PRSS2 ESRRG

1.90e-0429883CID006432721
DrugN-benzoyl-L-tyrosine thiobenzyl ester

PRSS1 PRSS2

2.19e-046882CID000191444
DrugAg2SO4

PRSS1 PRSS2

2.19e-046882CID000159275
DrugN,N-dimethylglycylbenzocaine

PRSS1 PRSS2

2.19e-046882CID000188251
Drug2 up

PRSS1 PRSS2

2.19e-046882CID000193409
DrugN-benzoyltyrosine butylamide

PRSS1 PRSS2

2.19e-046882CID000125261
DrugCirculin A

PRSS1 PRSS2

2.19e-046882CID000065155
Drugazidobestatin

PRSS1 PRSS2

2.19e-046882CID000132261
Drug2-azidoatrazine

PRSS1 PRSS2

2.19e-046882CID003032432
Drug4-TAPAP

PRSS1 PRSS2

2.19e-046882CID000133476
DrugDb04336

PRSS1 PRSS2

2.19e-046882CID000002014
DrugBAME

NDST3 PRSS1 PRSS2

2.55e-0432883CID000150869
DrugZ-Glu-Tyr

PRSS1 PRSS2

3.06e-047882CID000096820
DrugKki 8

PRSS1 PRSS2

3.06e-047882CID000064584
DrugO-4-(ethoxybutyl)berbamine

PRSS1 PRSS2

3.06e-047882CID000188375
Drugpentaammineaquocobalt(III) tetrafluoroborate

PRSS1 PRSS2

3.06e-047882CID000412963
Drugbz-Ar

PRSS1 PRSS2

3.06e-047882CID000137302
Drugbromobutide

PRSS1 PRSS2

3.06e-047882CID000053079
Drugleupeptins

PRSS1 PRSS2

3.06e-047882CID003033938
DrugArg-OEt

PRSS1 PRSS2

3.06e-047882CID000439495
DrugInhibitor 61

PRSS1 PRSS2

3.06e-047882CID005327349
DrugKki 7

PRSS1 PRSS2

3.06e-047882CID003082667
DrugGly-Gly-Arg

PRSS1 PRSS2

3.06e-047882CID000133469
DrugCbz-phe-arg-chn2

PRSS1 PRSS2

3.06e-047882CID005492392
DrugAC1MC4ST

PRSS1 PRSS2 ATP6V0A4

3.34e-0435883CID002724375
DrugHMTi

PRSS1 PRSS2

4.07e-048882CID000195636
DrugAC1NDMP4

PRSS1 PRSS2

4.07e-048882CID004628293
DrugBio-Phe-CH2Cl

PRSS1 PRSS2

4.07e-048882CID000083924
DrugBio-Arg-CH2Cl

PRSS1 PRSS2

4.07e-048882CID000083923
Drug3,5-bis-trifluoromethylphenylboronic acid

PRSS1 PRSS2

4.07e-048882CID000156265
DrugAC1MCHYW

PRSS1 PRSS2

4.07e-048882CID002770087
Drugharderoporphyrin

PRSS1 PRSS2

4.07e-048882CID003081462
DrugBoc hydrazine

PRSS1 PRSS2

4.07e-048882CID000070091
DrugO-methyl-L-serine

PRSS1 PRSS2

4.07e-048882CID000088250
DrugSAHA; Up 200; 10uM; PC3; HT_HG-U133A

WDR19 PLXNA3 NDNF ST3GAL5 DOP1A

4.54e-041658854444_UP
Diseaselevel of carboxypeptidase N subunit 2 in blood serum

CPNE2 CYP11B2

8.35e-055862OBA_2041122
DiseasePANCREATITIS, HEREDITARY

PRSS1 PRSS2

8.35e-055862167800
DiseaseHereditary pancreatitis

PRSS1 PRSS2

8.35e-055862cv:C0238339
DiseaseAutosomal Dominant Hereditary Pancreatitis

PRSS1 PRSS2

8.35e-055862C4080064
Disease3-hydroxyanthranilate 3;4-dioxygenase measurement

CPNE2 CYP11B2

8.35e-055862EFO_0021997
DiseaseHereditary pancreatitis

PRSS1 PRSS2

1.75e-047862C0238339
Diseaseleucine-rich repeat-containing protein 15 measurement

CPNE2 CYP11B2

1.75e-047862EFO_0801761
Diseaseprotocadherin alpha-7 measurement

CPNE2 CYP11B2

1.75e-047862EFO_0801973
Diseasetyrosine-protein kinase JAK2 measurement

CPNE2 CYP11B2

2.32e-048862EFO_0020825
DiseasePancreatitis, Chronic

PRSS1 PRSS2

2.98e-049862C0149521
Diseaseprotein FAM163B measurement

CPNE2 CYP11B2

2.98e-049862EFO_0802936
Diseasebeta-defensin 1 measurement

CPNE2 CYP11B2

3.72e-0410862EFO_0801415
Disease3-hydroxyanthranilate 3,4-dioxygenase measurement

CPNE2 CYP11B2

4.54e-0411862EFO_0021862
Diseasecell growth regulator with EF hand domain protein 1 measurement

CPNE2 CYP11B2

4.54e-0411862EFO_0801461
Diseaseessential tremor

CPNE2 CYP11B2 ESRRG ZNF626

6.84e-04136864EFO_0003108
Diseaseintellectual disability (implicated_via_orthology)

NDST3 UBR4 CAPN11

1.39e-0375863DOID:1059 (implicated_via_orthology)
Diseaselingual gyrus volume measurement

IQCA1 ESRRG

1.39e-0319862EFO_0010314
Diseaseapolipoprotein L1 measurement

CPNE2 CYP11B2

2.41e-0325862EFO_0021854
Diseaseazoospermia (implicated_via_orthology)

NDST3 ESRRG

2.81e-0327862DOID:14227 (implicated_via_orthology)

Protein segments in the cluster

PeptideGeneStartEntry
ELPQQVVQYFKHKNL

CPNE2

526

Q96FN4
IPDIYNKQHVKELVN

ACTR8

236

Q9H981
KTAPYKNVNVQNFHI

ACTN4

176

O43707
QKSVELFYQLHNLVP

DOP1A

891

Q5JWR5
HIQVNDVNEYAPVFK

CLSTN1

151

O94985
LANHFQVQIPKIDVY

AGO4

31

Q9HCK5
YAVPKEFQNIQDVHL

CAPN11

471

Q9UMQ6
KLESAHNPQQIYFRK

AGTPBP1

861

Q9UPW5
LENVYDQFVHPQKRI

IQCA1

56

Q86XH1
NHSAYQPVIFAKVKT

NDST3

226

O95803
KIHPDQKNINAYVVF

RBM34

236

P42696
VDLIIKIYFKNVHPQ

CYB5R2

81

Q6BCY4
EVVLFHPNYNINGKK

CFB

551

P00751
FVQRKAHSVYNFEKP

ORC4

356

O43929
YHLKSEFQAIIPAVN

MSH3

646

P20585
DPKKLLTQHFVQENY

MAGEA3

241

P43357
NNFVQYKFSHLPAKE

KAT2B

226

Q92831
QVIPEVIKNFIQYFH

EIF3L

46

Q9Y262
QQNKEKVYIIAHVPV

SMPDL3A

241

Q92484
PHVLDFLKKIQDYQQ

DDX60L

511

Q5H9U9
KPQIIAHIQKGFNYT

DNAAF10

6

Q96MX6
LAQPHNFIYKVTKNI

FBXW12

81

Q6X9E4
QFAKEVLPKYFKHNN

HSF1

51

Q00613
VNVIKNPQFVFDIHK

PLXNA1

1751

Q9UIW2
VNVIKNPQFVFDIHK

PLXNA3

1726

P51805
LKNYEFPHLQNFIKE

ENPP4

41

Q9Y6X5
KKQVFYDILEPQNHE

FAM151B

251

Q6UXP7
EEHFFQPQKYNLQPK

PGM2

596

Q96G03
KQPIQYCVVINKEHN

NDNF

206

Q8TB73
KYPDFKQHVQINLNG

METTL16

26

Q86W50
NHGVVIQPAYKDKIN

CD200

81

P41217
NFVLKNIPHEAFVYQ

PANK4

156

Q9NVE7
DENNHPPVFQKKFYI

PCDH15

1136

Q96QU1
VFNIDAKHYQIEPLK

ADAM30

136

Q9UKF2
YQFVKNLVDQHEPKK

HENMT1

36

Q5T8I9
YVILFHPEQNVQKRK

GRM6

841

O15303
FIYQNPHIFKDKVVL

PRMT3

246

O60678
AVQHFYNIKLEGKVP

ESRRG

431

P62508
AYNLPVEGNIHVKKQ

GRPR

241

P30550
KVHQQIIYGSEQIPK

GALNTL5

51

Q7Z4T8
HTVLKQIAPEYFEKN

DENND6A

186

Q8IWF6
LPVYQVFAREKQQKA

ANK3

2756

Q12955
NNYHEVQKVVGPKQI

DNAH14

2456

Q0VDD8
YQQVPVEIVKSDFHK

IQUB

236

Q8NA54
IQKIYQELAFNRPQH

CYP11B2

271

P19099
NEQIPKYEKIHNFKV

CHN1

196

P15882
FKQYVGKHILFVNVA

GPX5

56

O75715
NQQYHKLFKDVPLEE

GRAMD2A

71

Q8IUY3
DNHEISVYQCKEPKQ

GAPDHS

141

O14556
VVFYNPNLKKVVEAH

RHOBTB3

256

O94955
HVFNILEQKPKDFYA

RP1

821

P56715
NLKKPQHVFSVLEDY

TRMT11

141

Q7Z4G4
QKKHSQHYQIPDDFV

TRIM33

1011

Q9UPN9
QFINAAKIIRHPKYN

PRSS3P2

86

Q8NHM4
HVIFQNVAKSYLPNA

TAX1BP1

16

Q86VP1
PFLAVDQKHNILLKY

NXPE3

391

Q969Y0
TVALQYPKAIFQKHR

SMG1

2646

Q96Q15
YAVLHFHKVQPQEPK

SIGLEC6

426

O43699
PVEFNHAINYVNKIK

SIN3A

301

Q96ST3
DPDHVKRAQKYAQQV

ST3GAL5

101

Q9UNP4
QFVNDYRHPVSVKKI

WDR19

506

Q8NEZ3
QYFVNEQSKHQKPRG

OSBPL10

106

Q9BXB5
HKKYALQDQKNFDPV

SPAG17

531

Q6Q759
KAFVVLNPDYKSHDQ

ACSM3

521

Q53FZ2
QHEQKLKKEDQPYYV

CHST4

231

Q8NCG5
QVHQPSLVKLYQEKV

PGBD2

446

Q6P3X8
IQDPLGKYHQVKTVQ

XIRP2

816

A4UGR9
KDVLHQNFESYKPEV

TTC13

486

Q8NBP0
KHQEIPFIQHIYQKG

ZNF596

81

Q8TC21
IELHNIAIEFNKPQY

VPS13A

281

Q96RL7
KSEYHIKPNQQDISF

VPS13A

2166

Q96RL7
QKIKEYFQQKESHFP

SYCP2L

41

Q5T4T6
AHAFRNEPKYKVVQD

HGS

116

O14964
LNDYHPKNVFNIKET

TIGD4

171

Q8IY51
HVVVYFIQNQAPKKI

USP25

806

Q9UHP3
EKQYVVEPNFANKAV

VIT

436

Q6UXI7
HYVQQAKQRVDEKPS

PRRC2B

2181

Q5JSZ5
QFINAAKIIRHPKYN

PRSS2

86

P07478
KQPVYNVEVKNAEFP

SLF1

396

Q9BQI6
QCDKYVKVLHQFPNS

ZNF626

146

Q68DY1
PLYKHQQEVQSFFVV

ATP6V0A4

631

Q9HBG4
PQLNHLLKDYFEKQV

ZGRF1

2071

Q86YA3
KVAIKYHQKEFVAQP

TRPC5

291

Q9UL62
VGIIDNHYPKTKIFQ

ERVK-19

431

Q9WJR5
QFINAAKIIRHPQYD

PRSS1

86

P07477
KAPVYLFEQVQHNLL

UBR4

871

Q5T4S7
FKALKNFPHYQQLQK

ZYG11A

431

Q6WRX3
PFQILVAANKAVHLY

TPRKB

51

Q9Y3C4
QELFKQVRLQYIHPA

KLHL38

216

Q2WGJ6
IIQQAFINVAKKHFG

MX2

526

P20592