Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionRNA polymerase II transcription regulatory region sequence-specific DNA binding

ZNF573 ZFP3 ZNF570 ZNF549 ZNF423 ZFP30 ZNF180 PEG3 ZNF267 ZNF322 ZFP14 ZNF75CP ZNF226 ZNF112 ZNF229 EZH2 ADNP ZNF496 ZNF623 ZNF879 ZNF546 ZNF3 ZNF250 ZNF34 ZNF18 ZSCAN20 ZNF35 ZFHX4 ZNF544 ZNF517 ZNF852 ZNF425 GLI4 ZNF197 ZFHX2 ZNF528 ZNF83 ZNF30 KDM6A ZFP2 MED12 ZFP62 ZNF287

1.35e-13145916643GO:0000977
GeneOntologyMolecularFunctionDNA-binding transcription factor activity, RNA polymerase II-specific

ZNF573 ZFP3 ZNF570 ZNF549 ZNF423 ZFP30 ZNF180 PEG3 ZNF267 ZNF322 ZFP14 ZNF75CP ZNF226 ZNF112 ZNF229 ADNP ZNF496 ZNF623 ZNF879 ZNF546 ZNF3 ZNF250 ZNF34 ZNF18 ZSCAN20 ZNF35 ZFHX4 ZNF544 ZNF517 ZNF852 ZNF425 GLI4 ZNF197 ZFHX2 ZNF528 ZNF83 ZNF30 ZFP2 ZFP62 ZNF287

4.15e-12141216640GO:0000981
GeneOntologyMolecularFunctionRNA polymerase II cis-regulatory region sequence-specific DNA binding

ZNF573 ZFP3 ZNF570 ZNF549 ZNF423 ZFP30 ZNF267 ZNF322 ZFP14 ZNF75CP ZNF226 ZNF112 ZNF229 EZH2 ZNF496 ZNF623 ZNF879 ZNF546 ZNF3 ZNF250 ZNF34 ZNF18 ZSCAN20 ZFHX4 ZNF544 ZNF852 GLI4 ZNF197 ZFHX2 ZNF528 ZNF83 ZNF30 KDM6A ZFP2 MED12 ZFP62 ZNF287

7.76e-12124416637GO:0000978
GeneOntologyMolecularFunctioncis-regulatory region sequence-specific DNA binding

ZNF573 ZFP3 ZNF570 ZNF549 ZNF423 ZFP30 ZNF267 ZNF322 ZFP14 ZNF75CP ZNF226 ZNF112 ZNF229 EZH2 ZNF496 ZNF623 ZNF879 ZNF546 ZNF3 ZNF250 ZNF34 ZNF18 ZSCAN20 ZFHX4 ZNF544 ZNF852 GLI4 ZNF197 ZFHX2 ZNF528 ZNF83 ZNF30 KDM6A ZFP2 MED12 ZFP62 ZNF287

1.45e-11127116637GO:0000987
GeneOntologyMolecularFunctionprolactin receptor binding

CSH1 CSH2 CSHL1

1.93e-0571663GO:0005148
GeneOntologyMolecularFunctiongrowth hormone receptor binding

CSH1 CSH2 CSHL1

6.49e-05101663GO:0005131
GeneOntologyBiologicalProcesspositive regulation of steroid hormone biosynthetic process

BMP6 CSH1 CSH2 CSHL1

2.73e-06131664GO:0090031
GeneOntologyBiologicalProcesspositive regulation of hormone biosynthetic process

BMP6 CSH1 CSH2 CSHL1

1.43e-05191664GO:0046886
GeneOntologyBiologicalProcessregulation of steroid hormone biosynthetic process

BMP6 CSH1 CSH2 CSHL1

3.79e-05241664GO:0090030
GeneOntologyBiologicalProcessgrowth hormone receptor signaling pathway

CSH1 CSH2 CSHL1 PIK3R1

5.27e-05261664GO:0060396
GeneOntologyBiologicalProcesspositive regulation of hormone metabolic process

BMP6 CSH1 CSH2 CSHL1

5.27e-05261664GO:0032352
GeneOntologyBiologicalProcesscellular response to growth hormone stimulus

CSH1 CSH2 CSHL1 PIK3R1

6.15e-05271664GO:0071378
GeneOntologyCellularComponentgrowth hormone receptor complex

CSH1 CSH2 CSHL1

1.00e-0561683GO:0070195
MousePhenodecreased pituitary gland weight

CSH1 CSH2 CSHL1

3.69e-0581243MP:0008938
MousePhenoabsent somatotrophs

CSH1 CSH2 CSHL1

5.50e-0591243MP:0008330
MousePhenoabsent lactotrophs

CSH1 CSH2 CSHL1

5.50e-0591243MP:0008333
Domainzf-C2H2

ZNF573 ZFP3 ZNF570 ZNF549 ZNF423 ZFP30 ZNF180 PEG3 ZNF267 ZNF200 ZNF322 ZFP14 ZNF226 ZNF112 ZNF229 ZNF235 ADNP ZNF496 ZNF623 ZNF879 ZNF546 ZNF3 ZNF250 ZNF34 ZNF18 ZSCAN20 ZNF35 ZFHX4 ZNF544 ZNF517 ZNF852 ZNF425 GLI4 ZNF197 ZFHX2 ZNF528 ZNF83 ZNF30 ZFP2 ZFP62 ZNF287

7.75e-2369316441PF00096
DomainZnf_C2H2/integrase_DNA-bd

ZNF573 ZFP3 ZNF570 ZNF549 ZNF423 ZFP30 ZNF180 PEG3 ZNF267 ZNF200 ZNF322 ZFP14 ZNF226 ZNF112 ZNF229 ZNF235 ADNP ZNF496 ZNF623 ZNF879 ZNF546 ZNF3 ZNF250 ZNF34 ZNF18 ZSCAN20 ZNF35 ZFHX4 ZNF544 ZNF517 ZNF852 ZNF425 GLI4 ZNF197 ZFHX2 ZNF528 ZNF83 ZNF30 ZFP2 ZFP62 ZNF287

8.19e-2369416441IPR013087
Domain-

ZNF573 ZFP3 ZNF570 ZNF549 ZNF423 ZFP30 ZNF180 PEG3 ZNF267 ZNF200 ZNF322 ZFP14 ZNF226 ZNF112 ZNF229 ZNF235 ZNF496 ZNF623 ZNF879 ZNF546 ZNF3 ZNF250 ZNF34 ZNF18 ZSCAN20 ZNF35 ZFHX4 ZNF544 ZNF517 ZNF852 ZNF425 GLI4 ZNF197 ZFHX2 ZNF528 ZNF83 ZNF30 ZFP2 ZFP62

3.00e-21679164393.30.160.60
DomainZINC_FINGER_C2H2_2

ZNF573 ZFP3 ZNF570 ZNF549 ZNF423 ZFP30 ZNF180 PEG3 ZNF267 ZNF200 ZNF322 ZFP14 ZNF226 ZNF112 ZNF229 ZNF235 ADNP ZNF496 ZNF623 ZNF879 ZNF546 ZNF3 ZNF250 ZNF34 ZNF18 ZSCAN20 ZNF35 ZFHX4 ZNF544 ZNF517 ZNF852 ZNF425 GLI4 ZNF197 ZFHX2 ZNF528 ZNF83 ZNF30 ZFP2 ZFP62 ZNF287

5.00e-2177516441PS50157
DomainZINC_FINGER_C2H2_1

ZNF573 ZFP3 ZNF570 ZNF549 ZNF423 ZFP30 ZNF180 PEG3 ZNF267 ZNF200 ZNF322 ZFP14 ZNF226 ZNF112 ZNF229 ZNF235 ADNP ZNF496 ZNF623 ZNF879 ZNF546 ZNF3 ZNF250 ZNF34 ZNF18 ZSCAN20 ZNF35 ZFHX4 ZNF544 ZNF517 ZNF852 ZNF425 GLI4 ZNF197 ZFHX2 ZNF528 ZNF83 ZNF30 ZFP2 ZFP62 ZNF287

5.50e-2177716441PS00028
DomainZnf_C2H2-like

ZNF573 ZFP3 ZNF570 ZNF549 ZNF423 ZFP30 ZNF180 PEG3 ZNF267 ZNF200 ZNF322 ZFP14 ZNF226 ZNF112 ZNF229 ZNF235 ADNP ZNF496 ZNF623 ZNF879 ZNF546 ZNF3 ZNF250 ZNF34 ZNF18 ZSCAN20 ZNF35 ZFHX4 ZNF544 ZNF517 ZNF852 ZNF425 GLI4 ZNF197 ZFHX2 ZNF528 ZNF83 ZNF30 ZFP2 ZFP62 ZNF287

1.34e-2079616441IPR015880
DomainZnf_C2H2

ZNF573 ZFP3 ZNF570 ZNF549 ZNF423 ZFP30 ZNF180 PEG3 ZNF267 ZNF200 ZNF322 ZFP14 ZNF226 ZNF112 ZNF229 ZNF235 ADNP ZNF496 ZNF623 ZNF879 ZNF546 ZNF3 ZNF250 ZNF34 ZNF18 ZSCAN20 ZNF35 ZFHX4 ZNF544 ZNF517 ZNF852 ZNF425 GLI4 ZNF197 ZFHX2 ZNF528 ZNF83 ZNF30 ZFP2 ZFP62 ZNF287

2.02e-2080516441IPR007087
DomainZnF_C2H2

ZNF573 ZFP3 ZNF570 ZNF549 ZNF423 ZFP30 ZNF180 PEG3 ZNF267 ZNF200 ZNF322 ZFP14 ZNF226 ZNF112 ZNF229 ZNF235 ADNP ZNF496 ZNF623 ZNF879 ZNF546 ZNF3 ZNF250 ZNF34 ZNF18 ZSCAN20 ZNF35 ZFHX4 ZNF544 ZNF517 ZNF852 ZNF425 GLI4 ZNF197 ZFHX2 ZNF528 ZNF83 ZNF30 ZFP2 ZFP62 ZNF287

2.32e-2080816441SM00355
DomainKRAB

ZNF573 ZNF570 ZNF549 ZFP30 ZNF180 ZNF267 ZFP14 ZNF226 ZNF112 ZNF229 ZNF235 ZNF496 ZNF879 ZNF546 ZNF3 ZNF250 ZNF34 ZNF18 ZSCAN20 ZNF544 ZNF517 ZNF852 ZNF425 ZNF197 ZNF528 ZNF30 ZNF287

1.93e-1736916427SM00349
DomainKRAB

ZNF573 ZNF570 ZNF549 ZFP30 ZNF180 ZNF267 ZFP14 ZNF226 ZNF112 ZNF229 ZNF235 ZNF496 ZNF879 ZNF546 ZNF3 ZNF250 ZNF34 ZNF18 ZSCAN20 ZNF544 ZNF517 ZNF852 ZNF425 ZNF197 ZNF528 ZNF30 ZNF287

2.07e-1737016427IPR001909
DomainKRAB

ZNF573 ZNF570 ZNF549 ZFP30 ZNF180 ZNF267 ZFP14 ZNF226 ZNF112 ZNF229 ZNF235 ZNF496 ZNF879 ZNF546 ZNF3 ZNF250 ZNF34 ZNF18 ZNF544 ZNF517 ZNF852 ZNF425 ZNF197 ZNF528 ZNF30 ZNF287

9.63e-1735816426PS50805
DomainKRAB

ZNF573 ZNF570 ZNF549 ZFP30 ZNF180 ZNF267 ZFP14 ZNF226 ZNF112 ZNF229 ZNF235 ZNF496 ZNF879 ZNF546 ZNF3 ZNF250 ZNF34 ZNF18 ZNF544 ZNF517 ZNF852 ZNF425 ZNF197 ZNF528 ZNF30 ZNF287

9.63e-1735816426PF01352
Domainzf-C2H2_6

ZNF573 ZNF570 ZNF549 ZNF423 ZFP30 PEG3 ZNF267 ZNF200 ZFP14 ZNF229 ZNF879 ZNF546 ZNF250 ZNF852 ZNF425 ZNF197 ZNF30 ZFP2 ZFP62

4.19e-1131416419PF13912
DomainSomatotropin

ZFHX4 CSH1 CSH2 CSHL1

1.97e-0771644IPR001400
DomainSCAN

PEG3 ZNF496 ZNF18 ZSCAN20 ZNF197 ZNF287

9.44e-06561646SM00431
DomainSCAN_BOX

PEG3 ZNF496 ZNF18 ZSCAN20 ZNF197 ZNF287

1.16e-05581646PS50804
DomainSCAN

PEG3 ZNF496 ZNF18 ZSCAN20 ZNF197 ZNF287

1.16e-05581646PF02023
DomainSCAN_dom

PEG3 ZNF496 ZNF18 ZSCAN20 ZNF197 ZNF287

1.16e-05581646IPR003309
DomainRetrov_capsid_C

PEG3 ZNF496 ZNF18 ZSCAN20 ZNF197 ZNF287

1.28e-05591646IPR008916
DomainSOMATOTROPIN_2

CSH1 CSH2 CSHL1

1.30e-0561643PS00338
DomainSOMATOTROPIN_1

CSH1 CSH2 CSHL1

1.30e-0561643PS00266
DomainHormone_1

CSH1 CSH2 CSHL1

1.30e-0561643PF00103
DomainARM-type_fold

SMG1 VPS11 DOCK9 APC2 HUWE1 PPP4R4 FOCAD FMNL3 NF1 NBEAL2 UNC79 NIPBL

4.68e-0533916412IPR016024
DomainNLGN4

NLGN4Y NLGN4X

7.66e-0521642IPR030025
Domain-

VPS11 AMBRA1 PLXNB2 WDFY2 SORT1 TBC1D31 NBEAL2 PRPF19 RMC1 WDSUB1 WDR62

1.79e-04333164112.130.10.10
DomainWD40/YVTN_repeat-like_dom

VPS11 AMBRA1 PLXNB2 WDFY2 SORT1 TBC1D31 NBEAL2 PRPF19 RMC1 WDSUB1 WDR62

1.88e-0433516411IPR015943
DomainPI3K_P85_iSH2

PIK3R1 PIK3R2

2.29e-0431642IPR032498
DomainPI3K_P85_iSH2

PIK3R1 PIK3R2

2.29e-0431642PF16454
DomainNlgn

NLGN4Y NLGN4X

7.53e-0451642IPR000460
DomainPI3kinase_P85

PIK3R1 PIK3R2

7.53e-0451642IPR001720
DomainSomatotropin_CS

CSH1 CSHL1

7.53e-0451642IPR018116
DomainRho_GTPase_activation_prot

GMIP PLXNB2 NF1 PIK3R1 PIK3R2

1.07e-03881645IPR008936
DomainC2H2_Znf_fam

PEG3 ZNF496 ZNF18

1.17e-03241643IPR027775
DomainWD40_repeat_dom

VPS11 AMBRA1 WDFY2 TBC1D31 NBEAL2 PRPF19 RMC1 WDSUB1 WDR62

1.27e-032971649IPR017986
DomainU_BOX

PRPF19 WDSUB1

1.56e-0371642PS51698
PathwayREACTOME_RNA_POLYMERASE_II_TRANSCRIPTION

ZNF573 ZNF570 ZNF549 ZFP30 ZNF180 GPS2 ZNF267 ZNF200 ZFP14 ZNF226 ZNF112 ZNF235 EZH2 ZNF496 ZNF546 ZNF3 ZNF250 ZNF34 ZNF18 ZNF544 ZNF517 ZNF425 ZNF197 EPC1 ZNF528 ZNF30 ZFP2 MED12 ZNF287

1.03e-05138712629M734
PathwayBIOCARTA_LONGEVITY_PATHWAY

CSH1 CSH2 CSHL1 PIK3R1

2.13e-05191264MM1513
PathwayBIOCARTA_AKT_PATHWAY

CSH1 CSH2 CSHL1 PIK3R1

7.81e-05261264MM1345
PathwayBIOCARTA_TFF_PATHWAY

CSH1 CSH2 CSHL1 PIK3R1

1.22e-04291264MM1522
PathwayREACTOME_PROLACTIN_RECEPTOR_SIGNALING

CSH1 CSH2 CSHL1

1.87e-04131263MM14516
PathwayBIOCARTA_GH_PATHWAY

CSH1 CSH2 CSHL1 PIK3R1

2.04e-04331264MM1404
Pubmed

Differential expansion of zinc-finger transcription factor loci in homologous human and mouse gene clusters.

ZNF180 ZNF226 ZNF112 ZNF229 ZNF235 ZNF3

4.26e-1020168612743021
Pubmed

Growth hormone and prolactin stimulate tyrosine phosphorylation of insulin receptor substrate-1, -2, and -3, their association with p85 phosphatidylinositol 3-kinase (PI3-kinase), and concomitantly PI3-kinase activation via JAK2 kinase.

CSH1 CSH2 CSHL1 PIK3R1 PIK3R2

1.91e-091216859624169
Pubmed

Neonatal lethality, dwarfism, and abnormal brain development in Dmbx1 mutant mice.

NEFM CSH1 CSH2 CSHL1

1.82e-087168415314164
Pubmed

The human growth hormone gene locus: structure, evolution, and allelic variations.

CSH1 CSH2 CSHL1

1.11e-07316833030680
Pubmed

Developmental control and alternative splicing of the placentally expressed transcripts from the human growth hormone gene cluster.

CSH1 CSH2 CSHL1

4.41e-07416831378436
Pubmed

Physical and linkage mapping of human chromosome 17 loci to dog chromosomes 9 and 5.

NF1 CSH1 CSH2 CSHL1

9.14e-071616849177778
Pubmed

Central growth hormone action regulates metabolism during pregnancy.

CSH1 CSH2 CSHL1

1.10e-065168331479305
Pubmed

Molecular evolution of growth hormone and receptor in the guinea-pig, a mammal unresponsive to growth hormone.

CSH1 CSH2 CSHL1

1.10e-065168310767558
Pubmed

Rescue of pituitary function in a mouse model of isolated growth hormone deficiency type II by RNA interference.

CSH1 CSH2 CSHL1

1.10e-065168318006625
Pubmed

Growth hormone prevents the development of autoimmune diabetes.

CSH1 CSH2 CSHL1

1.10e-065168324218587
Pubmed

Body composition of inactivated growth hormone (oMt1a-oGH) transgenic mice: generation of an obese phenotype.

CSH1 CSH2 CSHL1

1.10e-06516839546108
Pubmed

Transgene transmission to progeny by oMt1a-oGH transgenic mice.

CSH1 CSH2 CSHL1

1.10e-065168316201410
Pubmed

Genes that prolong life: relationships of growth hormone and growth to aging and life span.

CSH1 CSH2 CSHL1

1.10e-065168311487592
Pubmed

Overexpressed growth hormone (GH) synergistically promotes carcinogen-initiated liver tumour growth by promoting cellular proliferation in emerging hepatocellular neoplasms in female and male GH-transgenic mice.

CSH1 CSH2 CSHL1

1.10e-065168311318985
Pubmed

Identification of the glomerular podocyte as a target for growth hormone action.

CSH1 CSH2 CSHL1

1.10e-065168317272398
Pubmed

Glucose homeostasis and insulin sensitivity in growth hormone-transgenic mice: a cross-sectional analysis.

CSH1 CSH2 CSHL1

1.10e-065168320707609
Pubmed

Induction of mammary adenocarcinomas in metallothionein promoter-human growth hormone transgenic mice.

CSH1 CSH2 CSHL1

1.10e-06516831874564
Pubmed

Growth Hormone Deficiency and Excess Alter the Gut Microbiome in Adult Male Mice.

CSH1 CSH2 CSHL1

1.10e-065168332100023
Pubmed

Transgenic mice expressing bovine GH develop arthritic disorder and self-antibodies.

CSH1 CSH2 CSHL1

1.10e-065168310810296
Pubmed

Somatotropin transgenic mice have reduced jejunal active glucose transport rates.

CSH1 CSH2 CSHL1

1.10e-06516837965203
Pubmed

Adipocytokines and the regulation of lipid metabolism in growth hormone transgenic and calorie-restricted mice.

CSH1 CSH2 CSHL1

1.10e-065168317347312
Pubmed

Pleiotropic effects of growth hormone signaling in aging.

CSH1 CSH2 CSHL1

1.10e-065168321852148
Pubmed

Body composition, bone mass and microstructural analysis in GH-transgenic mice reveals that skeletal changes are specific to bone compartment and gender.

CSH1 CSH2 CSHL1

1.10e-065168312175649
Pubmed

Transgenic mice reveal novel activities of growth hormone in wound repair, angiogenesis, and myofibroblast differentiation.

CSH1 CSH2 CSHL1

1.10e-065168315070902
Pubmed

A novel missense mutation in the mouse growth hormone gene causes semidominant dwarfism, hyperghrelinemia, and obesity.

CSH1 CSH2 CSHL1

1.10e-065168314726450
Pubmed

UV photodegradation of murine growth hormone: chemical analysis and immunogenicity consequences.

CSH1 CSH2 CSHL1

1.10e-065168324758742
Pubmed

Consequences of overexpression of growth hormone in transgenic mice on liver cytochrome P450 enzymes.

CSH1 CSH2 CSHL1

1.10e-065168310076541
Pubmed

Overgrowth of skin in growth hormone transgenic mice depends on the presence of male gonads.

CSH1 CSH2 CSHL1

1.10e-065168310594738
Pubmed

Hypoxia and cytoplasmic alkalinization upregulate growth hormone expression in lymphocytes.

CSH1 CSH2 CSHL1

1.10e-065168323639351
Pubmed

Pituitary growth hormone network responses are sexually dimorphic and regulated by gonadal steroids in adulthood.

CSH1 CSH2 CSHL1

1.10e-065168321098290
Pubmed

Age-related changes in body composition of bovine growth hormone transgenic mice.

CSH1 CSH2 CSHL1

1.10e-065168318948397
Pubmed

Heterogeneous growth hormone (GH) gene mutations in familial GH deficiency.

CSH1 CSH2 CSHL1

1.10e-06516838496314
Pubmed

Exploring endocrine GH pattern in mice using rank plot analysis and random blood samples.

CSH1 CSH2 CSHL1

1.10e-065168321045135
Pubmed

Analysis of gender difference of cardiac risk biomarkers using hGH-transgenic mice.

CSH1 CSH2 CSHL1

1.10e-065168316508206
Pubmed

Growth hormone overexpression in the central nervous system results in hyperphagia-induced obesity associated with insulin resistance and dyslipidemia.

CSH1 CSH2 CSHL1

1.10e-065168315616010
Pubmed

Nitric oxide stimulates embryonic somatotroph differentiation and growth hormone mRNA and protein expression through a cyclic guanosine monophosphate-independent mechanism.

CSH1 CSH2 CSHL1

1.10e-065168319019400
Pubmed

The Effects of 20-kDa Human Placental GH in Male and Female GH-deficient Mice: An Improved Human GH?

CSH1 CSH2 CSHL1

1.10e-065168332556100
Pubmed

High frequency of mammary adenocarcinomas in metallothionein promoter-human growth hormone transgenic mice created from two different strains of mice.

CSH1 CSH2 CSHL1

1.10e-06516831525063
Pubmed

Obesity and elevated plasma leptin concentration in oMT1A-o growth hormone transgenic mice.

CSH1 CSH2 CSHL1

1.10e-065168311346667
Pubmed

Cardiac contractile function is enhanced in isolated ventricular myocytes from growth hormone transgenic mice.

CSH1 CSH2 CSHL1

1.10e-065168312010633
Pubmed

Developmentally regulated activation of a SINE B2 repeat as a domain boundary in organogenesis.

CSH1 CSH2 CSHL1

1.10e-065168317626886
Pubmed

Regulation of rapid signal transducer and activator of transcription-5 phosphorylation in the resting cells of the growth plate and in the liver by growth hormone and feeding.

CSH1 CSH2 CSHL1

1.10e-065168319359380
Pubmed

Growth hormone stimulates the selective trafficking of thymic CD4+CD8- emigrants to peripheral lymphoid organs.

CSH1 CSH2 CSHL1

1.10e-065168315316240
Pubmed

Involvement of insulin-like growth factor-1 in the effect of caloric restriction: regulation of plasma adiponectin and leptin.

CSH1 CSH2 CSHL1

1.10e-065168317301034
Pubmed

Growth hormone action in the developing neural retina: a proteomic analysis.

CSH1 CSH2 CSHL1

1.10e-065168318203262
Pubmed

Assignment of the porcine growth hormone gene to chromosome 12.

CSH1 CSH2 CSHL1

1.10e-06516832249485
Pubmed

Growth hormone stimulates adipogenesis of 3T3-L1 cells through activation of the Stat5A/5B-PPARgamma pathway.

CSH1 CSH2 CSHL1

1.10e-065168317242167
Pubmed

A single injection of double-stranded adeno-associated viral vector expressing GH normalizes growth in GH-deficient mice.

CSH1 CSH2 CSHL1

1.10e-065168318180319
Pubmed

Cloning and characterisation of the GH gene from the common dolphin (Delphinus delphis).

CSH1 CSH2 CSHL1

1.10e-065168312225773
Pubmed

The related genes encoding growth hormone and prolactin have been dispersed to chromosomes 10 and 17 in the rat.

CSH1 CSH2 CSHL1

1.10e-06516833780533
Pubmed

High, persistent hepatocellular proliferation and apoptosis precede hepatocarcinogenesis in growth hormone transgenic mice.

CSH1 CSH2 CSHL1

1.10e-065168310395045
Pubmed

Effect of genetic background on growth of mice hemizygous for wild-type or dwarf mutated bovine growth hormone transgenes.

CSH1 CSH2 CSHL1

1.10e-065168324190208
Pubmed

Brief report: short stature caused by a mutant growth hormone.

CSH1 CSH2 CSHL1

1.10e-06516838552145
Pubmed

Promotion of Joint Degeneration and Chondrocyte Metabolic Dysfunction by Excessive Growth Hormone in Mice.

CSH1 CSH2 CSHL1

1.10e-065168336762426
Pubmed

High molecular weight isoforms of growth hormone in cells of the immune system.

CSH1 CSH2 CSHL1

1.10e-065168321741628
Pubmed

Structure of the growth hormone-encoding gene and its promoter in mice.

CSH1 CSH2 CSHL1

1.10e-06516838647448
Pubmed

Thiol-Disulfide Exchange in Human Growth Hormone.

CSH1 CSH2 CSHL1

1.10e-065168326887678
Pubmed

The role of growth hormone in fetal mouse reproductive tract differentiation.

CSH1 CSH2 CSHL1

1.10e-06516838756530
Pubmed

GH Knockout Mice Have Increased Subcutaneous Adipose Tissue With Decreased Fibrosis and Enhanced Insulin Sensitivity.

CSH1 CSH2 CSHL1

1.10e-065168331099824
Pubmed

Hot spots for growth hormone gene deletions in homologous regions outside of Alu repeats.

CSH1 CSH2 CSHL1

1.10e-06516831980158
Pubmed

Vitamin D3 cannot revert desensitization of growth hormone (GH)-induced STAT5-signaling in GH-overexpressing mice non-calcemic tissues.

CSH1 CSH2 CSHL1

1.10e-065168317881271
Pubmed

Neural growth hormone implicated in body weight sex differences.

CSH1 CSH2 CSHL1

1.10e-065168323861378
Pubmed

Growth hormone increases low-density lipoprotein receptor and HMG-CoA reductase mRNA expression in mesangial cells.

CSH1 CSH2 CSHL1

1.10e-065168312759574
Pubmed

Growth hormone production and action in N1E-115 neuroblastoma cells.

CSH1 CSH2 CSHL1

1.10e-065168319301152
Pubmed

Adipocyte insensitivity to insulin in growth hormone-transgenic mice.

CSH1 CSH2 CSHL1

1.10e-065168311350075
Pubmed

Transgenic mice overexpressing growth hormone (GH) have reduced or increased cardiac apoptosis through activation of multiple GH-dependent or -independent cell death pathways.

CSH1 CSH2 CSHL1

1.10e-065168318617616
Pubmed

Growth hormone and fertility in oMt1a-oGH transgenic mice.

CSH1 CSH2 CSHL1

1.10e-065168311570960
Pubmed

Promoter shuffling has occurred during the evolution of the vertebrate growth hormone gene.

CSH1 CSH2 CSHL1

1.10e-065168310974531
Pubmed

Hepatocellular alterations and dysregulation of oncogenic pathways in the liver of transgenic mice overexpressing growth hormone.

CSH1 CSH2 CSHL1

1.10e-065168323428905
Pubmed

Cardiac expression of adenine nucleotide translocase-1 in transgenic mice overexpressing bovine GH.

CSH1 CSH2 CSHL1

1.10e-065168317761891
Pubmed

Requirement of FAT and DCHS protocadherins during hypothalamic-pituitary development.

FAT4 CSH1 CSH2 CSHL1

1.52e-0618168433108146
Pubmed

Growth hormone, acting in part through the insulin-like growth factor axis, rescues developmental, but not metabolic, activity in the mammary gland of mice expressing a single allele of the prolactin receptor.

CSH1 CSH2 CSHL1

2.19e-066168312399427
Pubmed

GH modulates hepatic epidermal growth factor signaling in the mouse.

CSH1 CSH2 CSHL1

2.19e-066168320032199
Pubmed

Growth inhibition in giant growth hormone transgenic mice by overexpression of insulin-like growth factor-binding protein-2.

CSH1 CSH2 CSHL1

2.19e-066168311316754
Pubmed

The rise in growth hormone during starvation does not serve to maintain glucose levels or lean mass but is required for appropriate adipose tissue response in female mice.

CSH1 CSH2 CSHL1

2.19e-066168323150490
Pubmed

Nucleotide sequence of mouse prolactin and growth hormone mRNAs and expression of these mRNAs during pregnancy.

CSH1 CSH2 CSHL1

2.19e-06616832991252
Pubmed

Third party data gene data set of eutherian growth hormone genes.

CSH1 CSH2 CSHL1

2.19e-066168326697363
Pubmed

Effects of long-term treatment with growth hormone-releasing peptide-2 in the GHRH knockout mouse.

CSH1 CSH2 CSHL1

2.19e-066168315985453
Pubmed

Phosphorylation of sterol regulatory element-binding protein (SREBP)-1a links growth hormone action to lipid metabolism in hepatocytes.

CSH1 CSH2 CSHL1

2.19e-066168320863500
Pubmed

Biological evidence that SOCS-2 can act either as an enhancer or suppressor of growth hormone signaling.

CSH1 CSH2 CSHL1

2.19e-066168312208853
Pubmed

Involvement of growth hormone as a regulating factor in sex differences of mouse hepatic aldehyde oxidase.

CSH1 CSH2 CSHL1

2.19e-06616839175714
Pubmed

Disruption of growth hormone signaling retards early stages of prostate carcinogenesis in the C3(1)/T antigen mouse.

CSH1 CSH2 CSHL1

2.19e-066168316141391
Pubmed

Sex differences in thrombosis in mice are mediated by sex-specific growth hormone secretion patterns.

CSH1 CSH2 CSHL1

2.19e-066168318618017
Pubmed

Growth hormone is a positive regulator of adiponectin receptor 2 in 3T3-L1 adipocytes.

CSH1 CSH2 CSHL1

2.19e-066168314759511
Pubmed

Administration of human insulin-like growth factor-binding protein-1 increases circulating levels of growth hormone in mice.

CSH1 CSH2 CSHL1

2.19e-066168315166120
Pubmed

Osteocalcin induces growth hormone/insulin-like growth factor-1 system by promoting testosterone synthesis in male mice.

CSH1 CSH2 CSHL1

2.19e-066168324691732
Pubmed

CTCF mutation at R567 causes developmental disorders via 3D genome rearrangement and abnormal neurodevelopment.

CSH1 CSH2 CSHL1

2.19e-066168338951485
Pubmed

Evidence that growth hormone exerts a feedback effect on stomach ghrelin production and secretion.

CSH1 CSH2 CSHL1

2.19e-066168314530511
Pubmed

Growth hormone induces hepatic production of fibroblast growth factor 21 through a mechanism dependent on lipolysis in adipocytes.

CSH1 CSH2 CSHL1

2.19e-066168321849508
Pubmed

Stimulation of endogenous pulsatile growth hormone secretion by activation of growth hormone secretagogue receptor reduces the fat accumulation and improves the insulin sensitivity in obese mice.

CSH1 CSH2 CSHL1

2.19e-066168333368660
Pubmed

Inhibition of growth hormone action improves insulin sensitivity in liver IGF-1-deficient mice.

CSH1 CSH2 CSHL1

2.19e-066168314702113
Pubmed

Systemic over-secretion of growth hormone in transgenic mice results in a specific pattern of skeletal modeling and adaptation.

CSH1 CSH2 CSHL1

2.19e-06616839556071
Pubmed

Transgenic studies with a keratin promoter-driven growth hormone transgene: prospects for gene therapy.

CSH1 CSH2 CSHL1

2.19e-06616838990189
Pubmed

Evidence that sensitivity to growth hormone (GH) is growth period and tissue type dependent: studies in GH-deficient lit/lit mice.

CSH1 CSH2 CSHL1

2.19e-066168312933669
Pubmed

Insulin-like growth factor 1 mediates negative feedback to somatotroph GH expression via POU1F1/CREB binding protein interactions.

CSH1 CSH2 CSHL1

2.19e-066168322890843
Pubmed

Disruption of growth hormone receptor gene causes diminished pancreatic islet size and increased insulin sensitivity in mice.

CSH1 CSH2 CSHL1

2.19e-066168315138153
Pubmed

Growth Hormone (GH) Deficient Mice With GHRH Gene Ablation Are Severely Deficient in Vaccine and Immune Responses Against Streptococcus pneumoniae.

CSH1 CSH2 CSHL1

2.19e-066168330333823
Pubmed

GH/STAT5 signaling during the growth period in livers of mice overexpressing GH.

CSH1 CSH2 CSHL1

2.19e-066168325691498
Pubmed

The role of GH in adipose tissue: lessons from adipose-specific GH receptor gene-disrupted mice.

CSH1 CSH2 CSHL1

2.19e-066168323349524
Pubmed

Deleting IGF-1 receptor from forebrain neurons confers neuroprotection during stroke and upregulates endocrine somatotropin.

CSH1 CSH2 CSHL1

2.19e-066168326762506
CytobandEnsembl 112 genes in cytogenetic band chr19q13

ZNF573 HIPK4 ZNF570 ZNF549 ZFP30 ZNF180 PEG3 ZFP14 ZNF226 ZNF112 ZNF229 ZNF235 ZNF546 CEACAM21 ZNF544 ALDH16A1 ZNF528 ZNF83 ZNF30 WDR62

1.78e-08119216820chr19q13
Cytoband19q13.2

HIPK4 ZNF180 ZNF226 ZNF112 ZNF235 ZNF546 CEACAM21

2.66e-06164168719q13.2
Cytoband19q13.12

ZNF573 ZNF570 ZFP30 ZFP14 WDR62

7.09e-0672168519q13.12
Cytoband8q24.3

ZNF623 ZNF250 ZNF34 ZNF517 GLI4

6.31e-0511316858q24.3
Cytoband17q24.2

CSH1 CSH2 CSHL1

1.82e-0430168317q24.2
Cytoband16p12.3

SMG1 SYT17 COQ7

2.65e-0434168316p12.3
CytobandEnsembl 112 genes in cytogenetic band chr8q24

ZNF623 FAM135B ZNF250 ZNF34 TBC1D31 ZNF517 GLI4

3.55e-043551687chr8q24
CytobandEnsembl 112 genes in cytogenetic band chr17q23

TANC2 CSH1 CSH2 CSHL1

1.02e-031201684chr17q23
Cytoband1p34.3

GRIK3 ZSCAN20 MANEAL

1.55e-036216831p34.3
GeneFamilyZinc fingers C2H2-type|ZF class homeoboxes and pseudogenes

ZNF573 ZFP3 ZNF570 ZNF549 ZNF423 ZFP30 ZNF180 PEG3 ZNF267 ZNF200 ZNF322 ZFP14 ZNF226 ZNF112 ZNF229 ZNF235 ZNF496 ZNF623 ZNF879 ZNF546 ZNF3 ZNF250 ZNF34 ZNF18 ZSCAN20 ZNF35 ZNF544 ZNF517 ZNF852 ZNF425 GLI4 ZNF197 ZFHX2 ZNF528 ZNF83 ZNF30 ZFP2 ZFP62 ZNF287

1.11e-257181183928
GeneFamilyGrowth hormone family

CSH1 CSH2 CSHL1

5.34e-06611831175
GeneFamilyZinc fingers C2H2-type|ZF class homeoboxes and pseudogenes

ADNP ZFHX4 ZFHX2

1.16e-04151183529
GeneFamilyIntermediate filaments Type IV

SYNM NEFM

6.23e-0461182611
GeneFamilyU-box domain containing

PRPF19 WDSUB1

8.68e-0471182365
GeneFamilyWD repeat domain containing

AMBRA1 WDFY2 TBC1D31 NBEAL2 PRPF19 WDSUB1 WDR62

1.67e-032621187362
CoexpressionBREDEMEYER_RAG_SIGNALING_NOT_VIA_ATM_UP

SMG1 ZFP14 CSH1 CSH2 CSHL1 RAB32

7.91e-06741676MM769
ToppCell5'-Adult-LargeIntestine-Mesenchymal-fibroblastic-Stromal_2_(NPY+)|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

COL5A1 COL6A2 IP6K3 OBSCN LAMA4 FAM135B COLEC12 NLGN4X

6.02e-071881688997dcfc4f08738ab398d8abc15e4fd2fc6619862
ToppCellLPS-IL1RA-Endothelial|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

FAT4 UACA MYO6 ZNF423 DOCK9 DYSF FAM171A1 TANC1

7.63e-07194168843f92b0533e26633dc94cce554045d641ef8fd76
ToppCellLPS-IL1RA-Endothelial-Endothelial|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

FAT4 UACA MYO6 ZNF423 DOCK9 DYSF FAM171A1 TANC1

7.63e-0719416881d39d968730a7e85b6161c1c8a6bd38afe9bcad7
ToppCellPND01-Mesenchymal-Mesenchymal_structural-Fibroblastic-AF1-AF1_mature|PND01 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

COL6A2 SYNM PEG3 LAMA4 EZH2 PPP4R4 COLEC12 PIK3R1

8.56e-07197168806a0d7062dadda656decaf77dcef9a10b5f2698d
ToppCellCOVID-19-lung-Capillary_1|lung / Disease (COVID-19 only), tissue and cell type

FAT4 UACA ZNF423 DOCK9 DYSF FAM171A1 BMP6 NLGN4X

8.56e-0719716887e86ff9dafcbaaa7464d61484dd48bfeb7eae6e4
ToppCellPND01-Mesenchymal-Mesenchymal_structural-Fibroblastic-AF1|PND01 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

COL6A2 SYNM PEG3 LAMA4 EZH2 PPP4R4 COLEC12 PIK3R1

8.56e-071971688d35c7a36135b5ed6a7bf2f934849678eba2a0177
ToppCellFetal_29-31_weeks-Mesenchymal|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

COL5A1 COL6A2 FAT4 UACA LAMA4 STEAP2 FREM1 COLEC12

8.89e-07198168821cf4d81386761d09d0f6829c01c198e5524176d
ToppCellnormal_Pleural_Fluid-Myeloid_cells-CD163+CD14+_DCs|normal_Pleural_Fluid / Location, Cell class and cell subclass

TANC2 SYNM GALNT12 PLXNB2 ZNF546 FSIP2 ZSCAN20

4.84e-0617616877a74217b7fa1032b918f00a3972dff5fab74671a
ToppCellwk_15-18-Epithelial-PNS-Schwann_precursor|wk_15-18 / Celltypes from embryonic and fetal-stage human lung

SYNM PGAP4 GRIK3 INPP5F NF1 NLGN4X MANEAL

5.02e-0617716875357359e6c2161a37f39a6b3b78449f5cbc327d1
ToppCelldroplet-Fat-Gat-18m-Endothelial-nan|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CDH23 DYSF BMP6 GBP4 RAPGEF3 NBEAL2 TANC1

5.40e-06179168708cf9986804a6417a9afb19b50c69a3554f71ec6
ToppCellPCW_07-8.5-Neuronal-Neuronal_postreplicative|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

APC2 PPM1E GRIK3 NEFM NLGN4X PTPRR MANEAL

6.95e-0618616872fdd0a80ad31cf017aafcf5dcf760ebd786b98c1
ToppCellsystemic_lupus_erythematosus-flare-Lymphocytic_NK-T_mait-male|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex

COL6A2 ZNF200 KLHL22 FMNL3 ZNF250 ZNF197 ZNF528

6.95e-061861687927723ad579bbd9947ff525bd501e222d3fa9289
ToppCell10x5'-GI_small-bowel-Lymphocytic_T_CD4-T_CD4/CD8|GI_small-bowel / Manually curated celltypes from each tissue

SMG1 HUWE1 NF1 TMEM131L KDM6A NIPBL GOLGB1

7.45e-061881687ab9b725d6e0cdab8e9ddda6dee09e14730e9a578
ToppCelldroplet-Fat-SCAT-30m-Endothelial-endothelial_cell|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

UACA SYNM DOCK9 DYSF GBP4 PTPRR RAPGEF3

7.45e-0618816875cf060bb8adaefa9964187195d67993c1248ef47
ToppCelldroplet-Fat-SCAT-30m-Endothelial|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

UACA SYNM DOCK9 DYSF GBP4 PTPRR RAPGEF3

7.45e-061881687449f9602df3c83b2110eb479a00d428d1b55b423
ToppCelldroplet-Mammary_Gland-nan-21m-Mesenchymal-stromal_cell|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

COL5A1 COL6A2 EMILIN2 LAMA4 ADAMTS5 COLEC12 ZFHX4

7.71e-061891687bc54ffd7bd1627a36747a80ce5139e4a69928400
ToppCelldroplet-Mammary_Gland-nan-21m-Mesenchymal-stromal_cell|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

COL5A1 COL6A2 EMILIN2 LAMA4 ADAMTS5 COLEC12 ZFHX4

7.98e-061901687f3ca94a31a35eed5fecf3c4b8c957e1bc4150158
ToppCelldroplet-Mammary_Gland-nan-21m-Mesenchymal|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

COL5A1 COL6A2 EMILIN2 LAMA4 ADAMTS5 COLEC12 ZFHX4

7.98e-061901687c2cd1eb674162ee40502c3380b7245c85079c7ce
ToppCellE15.5-Mesenchymal-mesenchymal_fibroblast-mesenchymal_alveolar_niche_cell|E15.5 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

COL5A1 COL6A2 FAT4 PEG3 TENM2 COLEC12 TRPM5

8.26e-061911687053b3664f509baa107feaf90730f80ebf9ac8f14
ToppCellLPS-IL1RA+antiTNF-Endothelial|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

FAT4 UACA MYO6 ZNF423 DOCK9 DYSF FAM171A1

8.55e-06192168704f5a2e3dd6beff027b89d66eefdd92036e041af
ToppCellLPS-IL1RA+antiTNF-Endothelial-Endothelial|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

FAT4 UACA MYO6 ZNF423 DOCK9 DYSF FAM171A1

8.55e-061921687c07d7b40b2aa4eb27ac85801c014a656e2fd01dc
ToppCellChildren_(3_yrs)-Mesenchymal-matrix_fibroblast_2_cell-D046|Children_(3_yrs) / Lineage, Cell type, age group and donor

COL5A1 COL6A2 FAT4 ZNF423 LAMA4 STEAP2 FREM1

8.55e-061921687e0f4e4470a71bfa81d9dcd8594e5f82aafc24f81
ToppCellLPS-IL1RA+antiTNF-Endothelial-Endothelial-Gen_Cap|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

FAT4 UACA ZNF423 DOCK9 DYSF FAM171A1 BMP6

8.84e-061931687e09387af84d2a0a526e54d4793e6e06c6739db53
ToppCellLPS-antiTNF-Endothelial-Endothelial|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

FAT4 UACA MYO6 ZNF423 DOCK9 DYSF FAM171A1

8.84e-06193168702f633b016ab19bfa65bfd0cf32f000549a62148
ToppCellLPS-antiTNF-Endothelial-Endothelial-Gen_Cap|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

FAT4 UACA ZNF423 DOCK9 DYSF FAM171A1 BMP6

8.84e-0619316876e1982d089a9de628e6006d23ff78a223fbd9f47
ToppCellLPS_only-Endothelial-Endothelial-Gen_Cap|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

FAT4 UACA ZNF423 DOCK9 DYSF FAM171A1 BMP6

8.84e-061931687af5108260783e69a7d67896c5bf64f862525926d
ToppCellControl-Endothelial-Endothelial-Gen_Cap|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

FAT4 UACA ZNF423 DOCK9 DYSF FAM171A1 BMP6

8.84e-061931687e1d546165dcc2392f540162206852c4717d7306f
ToppCellLPS-antiTNF-Endothelial|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

FAT4 UACA MYO6 ZNF423 DOCK9 DYSF FAM171A1

8.84e-0619316875122b1ffba42de190061be34ecdc6176f84e56a3
ToppCellAdult-Mesenchymal-matrix_fibroblast_1_cell-D231|Adult / Lineage, Cell type, age group and donor

COL5A1 COL6A2 UACA LAMA4 STEAP2 TENM2 FREM1

8.84e-061931687ef2f456c094e6e3c6ee81e0668c953cb8d0e1c0a
ToppCellChildren_(3_yrs)-Mesenchymal-matrix_fibroblast_2_cell|Children_(3_yrs) / Lineage, Cell type, age group and donor

COL5A1 COL6A2 FAT4 ZNF423 LAMA4 STEAP2 FREM1

8.84e-0619316879ab47b360bee1d4f1092c2269e58acebe9584021
ToppCell10x3'2.3-week_17-19-Mesenchymal_fibro-stroma-endosteal_fibroblast|week_17-19 / cell types per 3 fetal stages;per 3',per 5'

COL6A2 LAMA4 STEAP2 PPP4R4 COLEC12 BMP6 GPNMB

9.14e-06194168769362e13158033de44f90f3773db6c0f27de8cb3
ToppCellLPS-IL1RA-Endothelial-Endothelial-Gen_Cap|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

FAT4 UACA ZNF423 DOCK9 DYSF FAM171A1 BMP6

9.14e-0619416870b9cd96fa0b616da7cc90e92ff71157e9bba518f
ToppCellLPS_only-Endothelial|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

FAT4 UACA ZNF423 DOCK9 DYSF FAM171A1 TANC1

9.14e-06194168758f069efdefa0366033764446b9d6ffd4a17807e
ToppCellLPS_only-Endothelial-Endothelial|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

FAT4 UACA ZNF423 DOCK9 DYSF FAM171A1 TANC1

9.14e-061941687bfd92ec75facb0ba55c31e5f2e089d983b3d0169
ToppCellPND01-Mesenchymal-Mesenchymal_structural|PND01 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

COL6A2 SYNM PEG3 LAMA4 EZH2 PPP4R4 COLEC12

9.46e-0619516876bb6349d6ec8da094fe1c7c590021989337aeb0b
ToppCellPCW_10-12-Mesenchymal-Mesenchymal_fibroblastic-mes_immature3_(17)|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung

COL5A1 COL6A2 FAT4 LAMA4 TENM2 FREM1 COLEC12

9.46e-0619516871cdf5f296029ae424d9dba42e86a6d111e4896e6
ToppCellPND01-Mesenchymal-Mesenchymal_structural-Fibroblastic|PND01 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

COL6A2 SYNM PEG3 LAMA4 EZH2 PPP4R4 COLEC12

9.46e-061951687a3b468125e48f072255cede7645f6692298ecf54
ToppCellChildren_(3_yrs)-Endothelial|Children_(3_yrs) / Lineage, Cell type, age group and donor

FAT4 UACA ZNF423 DOCK9 DYSF FAM171A1 TANC1

9.46e-061951687094cf6591daa5ffad36e44122b6f524a3a34c2fd
ToppCellChildren_(3_yrs)-Mesenchymal|Children_(3_yrs) / Lineage, Cell type, age group and donor

COL5A1 COL6A2 UACA LAMA4 STEAP2 FREM1 PIK3R1

9.78e-061961687bc94909f9b2dc08a59eef1914148b69720569c8f
ToppCell5'-Parenchyma_lung-Endothelial-Blood_vessel_EC-pulmonary_artery_endothelial_cell-EC_arterial-EC_arterial_L.2.4.1.3|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

FAT4 UACA DOCK9 LAMA4 MYZAP NLGN4X GBP4

1.04e-051981687d5990cab01de6e6f3757f5a50ef70ced711bb1fa
ToppCell10x3'2.3-week_14-16-Mesenchymal_osteo-stroma-osteoblast_precursor|week_14-16 / cell types per 3 fetal stages;per 3',per 5'

COL6A2 UACA MYO6 LAMA4 COLEC12 ZFHX4 TANC1

1.04e-0519816879d61483b0decac2fe90045b3474843360b2c49b3
ToppCellTransplant_Alveoli_and_parenchyma-Endothelial-Lymphatic|Endothelial / Tissue, Lineage and Cell class of Lung Cells from 10X

COL6A2 SYNM LAMA4 PGAP4 ADAMTS5 OMG COLEC12

1.04e-0519816877a99c341736a4a2ac48ef8e2f7951f21a7378946
ToppCell10x5'v1-week_14-16-Mesenchymal_osteo-stroma-osteoblast_precursor|week_14-16 / cell types per 3 fetal stages;per 3',per 5'

COL5A1 COL6A2 MYO6 LAMA4 COLEC12 ZFHX4 TANC1

1.04e-051981687bc9c9f2c87282b5ef8514773e065d2a6b5dde338
ToppCellFibroblasts|World / Immune cells in Rheumatoid Arthritis Joint Synovial Tissues

COL5A1 COL6A2 UACA LAMA4 STEAP2 COLEC12 ZFHX4

1.08e-05199168740de6d4a31cf22efa2864f79e4ec8e2b7bfc9d4a
ToppCellMesenchymal|World / Lineage, Cell type, age group and donor

COL5A1 COL6A2 FAT4 UACA LAMA4 STEAP2 FREM1

1.08e-0519916874bac110c2b3609f6ee5d0e3275da0824a6240270
ToppCellBronchus_Control_(B.)-Stromal-TX-Fibroblasts-2,_SCARA5|Bronchus_Control_(B.) / Sample group, Lineage and Cell type

COL5A1 COL6A2 FAT4 ZNF423 LAMA4 ADAMTS5 ZFHX4

1.11e-0520016872022df85df94ab8cbb4e80e3fe9894c01051c5e0
ToppCell10x5'v1-week_14-16-Mesenchymal_osteo|week_14-16 / cell types per 3 fetal stages;per 3',per 5'

COL5A1 COL6A2 MYO6 LAMA4 COLEC12 ZFHX4 TANC1

1.11e-052001687780d47f8eff630020dfae32218de495a7e9dbad6
ToppCellTracheal-NucSeq-Stromal-Fibroblastic-Fibro_perichondrial|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

COL5A1 COL6A2 FAT4 FMNL3 COLEC12 NLGN4X ZFHX4

1.11e-052001687a4ec0e80f5422b91b85264a9bb74568dd577e285
ToppCell10x5'v1-week_14-16-Mesenchymal_osteo-stroma|week_14-16 / cell types per 3 fetal stages;per 3',per 5'

COL5A1 COL6A2 MYO6 LAMA4 COLEC12 ZFHX4 TANC1

1.11e-05200168728dd127787a57276253548d1f030814b1af64481
ToppCell10x5'v1-week_14-16-Mesenchymal_osteo-stroma-osteochondral_precursor|week_14-16 / cell types per 3 fetal stages;per 3',per 5'

COL5A1 COL6A2 UACA LAMA4 COLEC12 ZFHX4 TANC1

1.11e-052001687ad3fb8ef0be45032369d1325024787fbe1dfb8d6
ToppCellBronchus_Control_(B.)-Stromal-TX|Bronchus_Control_(B.) / Sample group, Lineage and Cell type

COL5A1 COL6A2 FAT4 ZNF423 LAMA4 ADAMTS5 ZFHX4

1.11e-05200168769b41f5fb370aa8840a9ad7919d03ef1e57d1b5b
ToppCellTracheal-NucSeq-Stromal-Fibroblastic|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

COL5A1 COL6A2 FAT4 LAMA4 FREM1 COLEC12 GPNMB

1.11e-052001687b4ccffdd79526c85e5273d27b668dbddcddba1ee
ToppCellBronchial-NucSeq-Stromal-Fibroblastic|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

COL5A1 COL6A2 FAT4 UACA LAMA4 STEAP2 FREM1

1.11e-052001687cae972324d1dfea6efeaf6013f265c7c6bb48db4
ToppCellLPS_only-Endothelial-Endothelial-Alv_Cap|LPS_only / Treatment groups by lineage, cell group, cell type

UACA MYO6 DOCK9 MYZAP DYSF FAM171A1 TANC1

1.11e-052001687432384faeade8e609154fab3d96c955a8ec868dd
ToppCellKidney-Fibroblasts|Kidney / Skin and Kidney Cells in Lupus Nephritis Patients.

COL6A2 EMILIN2 ADAMTS5 ZNF3 ZSCAN20 ZFHX4 GPNMB

1.11e-0520016872c265ad8314a21bce50ac21b16da2fea125366ea
ToppCellTracheal-NucSeq-Stromal-Fibroblastic-Fibro_adventitial|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

COL5A1 COL6A2 FAT4 LAMA4 FREM1 COLEC12 GPNMB

1.11e-0520016870c25d56292b9e5fefa4521b72635449be1ffd6fe
ToppCellChildren_(3_yrs)-Endothelial-endothelial_cell_of_bronchial_vessel|Children_(3_yrs) / Lineage, Cell type, age group and donor

FAT4 UACA DYSF BMP6 PTPRR TANC1

3.63e-051631686977a970b1296234c22178420294cea73506ee02f
ToppCell5'-Adult-SmallIntestine-Mesenchymal-fibroblastic-Stromal_2_(NPY+)|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

COL5A1 COL6A2 OBSCN LAMA4 ADAMTS5 NLGN4X

3.75e-051641686a764b79a127c8f360af0b79a1da64658badf0dfa
ToppCellAdult-Mesenchymal-chondrocyte-D175|Adult / Lineage, Cell type, age group and donor

COL5A1 COL6A2 ZNF570 ZNF423 LAMA4 ZFHX4

4.29e-05168168614071b961c9bdb54a8259b12a88237b802cbde36
ToppCellfacs-Mammary_Gland-Mammary_Gland-21m-Mesenchymal|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

COL5A1 COL6A2 EMILIN2 DUOX2 ADAMTS5 GPNMB

4.44e-051691686bb43abad2c049b7f4d307737347290e01b3339a3
ToppCellfacs-Mammary_Gland-Mammary_Gland-21m-Mesenchymal-stromal_cell|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

COL5A1 COL6A2 EMILIN2 DUOX2 ADAMTS5 GPNMB

4.44e-0516916865f18e3f40a5b1b167903f37516ec8181e889c7c5
ToppCellfacs-Mammary_Gland-Mammary_Gland-21m-Mesenchymal-stromal_cell|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

COL5A1 COL6A2 EMILIN2 DUOX2 ADAMTS5 GPNMB

4.44e-0516916868bfa2d3bb541d02f55d7c95b8fd156c8403befca
ToppCellEndothelial-B-Donor_06|World / lung cells shred on cell class, cell subclass, sample id

COL6A2 SYNM LAMA4 ADAMTS5 DYSF FREM1

4.89e-0517216868a527dff06d841a86c7eb04a1dd9630787294da4
ToppCelltumor_Lymph_Node_/_Brain-T/NK_cells-CD8+/CD4+_Mixed_Th|T/NK_cells / Location, Cell class and cell subclass

SORT1 ZNF517 TMEM131L PLD2 DOT1L KDM6A

5.05e-05173168642c911ed16fabdabef063830e8407192d8bde950
ToppCell343B-Fibroblasts-Fibroblast-H-|343B / Donor, Lineage, Cell class and subclass (all cells)

COL5A1 ZNF423 LAMA4 ADAMTS5 STEAP2 FREM1

5.22e-0517416862627c3983009839fedbc5e3f628739dc026447f4
ToppCell343B-Fibroblasts-Fibroblast-H|343B / Donor, Lineage, Cell class and subclass (all cells)

COL5A1 ZNF423 LAMA4 ADAMTS5 STEAP2 FREM1

5.22e-051741686507a33e58f62e2b72f0bcc743e84dbd0bf705a15
ToppCell10x_5'_v1-Neoplastic-Differentiated-like-MES-like|10x_5'_v1 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

PPM1E STEAP2 TEX26 GPNMB RAB32 WDR62

5.39e-0517516862dcb5145835c3872d0f92f3ece23730cf65487bd
ToppCell10x_5'_v1-Neoplastic|10x_5'_v1 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

PPM1E STEAP2 TEX26 GPNMB RAB32 WDR62

5.39e-051751686379f595be2273f662064c920d195a30491aa88d6
ToppCell10x_5'_v1-Neoplastic-Differentiated-like|10x_5'_v1 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

PPM1E STEAP2 TEX26 GPNMB RAB32 WDR62

5.39e-0517516863c3cbaeec6ef2f61e6b177c95b999752c2d83ddb
ToppCellfacs-Heart-RV-18m-Mesenchymal-fibroblast_of_cardiac_tissue|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

COL5A1 COL6A2 ADAMTS5 TMEM129 ZFHX4 PIK3R2

5.56e-051761686c0a084f7a8645262d61971f094689e02bf15b113
ToppCellfacs-Heart-RV-18m-Mesenchymal-fibroblast_of_cardiac_tissue|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

COL5A1 COL6A2 ADAMTS5 TMEM129 ZFHX4 PIK3R2

5.56e-051761686cccf9201f6e2da7524b911a5961d3b227edab222
ToppCellControl-Neuronal_cells-Neuronal_cells|Control / group, cell type (main and fine annotations)

ZNF423 DOCK9 LAMA4 DYSF FAM171A1 NLGN4X

5.56e-05176168698c07d26ba0dc0fe15ca0ea81f633d4591782bd1
ToppCell356C-Myeloid-Macrophage-FABP4+_Macrophage_3|Macrophage / Donor, Lineage, Cell class and subclass (all cells)

COL5A1 COL6A2 FAT4 LAMA4 ADAMTS5 STEAP2

5.56e-051761686bfa1633e1b7a8a2f04d37fa07284fe9bc0199f46
ToppCellControl-Neuronal_cells|Control / group, cell type (main and fine annotations)

ZNF423 DOCK9 LAMA4 DYSF FAM171A1 NLGN4X

5.56e-051761686c29d09ecf0eb17f767d78af4b7f2e7725c967ff8
ToppCellE18.5-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_airway-ASMC-ASMC_prolif|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

ZFP30 ADAMTS5 AGBL5 ZNF235 ZFHX4 ZNF287

5.56e-0517616864ed73c73972334f6dc4229920205547823252fa0
ToppCellnormal_Lung-Endothelial_cells-EPCs|normal_Lung / Location, Cell class and cell subclass

DSG3 DOCK9 FAM171A1 BMP6 GBP4 PTPRR

5.56e-05176168671d1bd425772d89d8c550b909e0ec0e36ff22a7e
ToppCelldroplet-Liver-hepatocytes-3m-Endothelial-endothelial_cell_of_hepatic_sinusoid|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FAT4 ZNF235 FAM171A1 SLC41A2 TANC1 ZNF287

5.74e-0517716868ef41ee5d63737b810ad7371b0437625e7e1badf
ToppCell(09)_Ionocytes-(3)_72hpi|(09)_Ionocytes / shred by cell type and Timepoint

CERK ZNF322 FMNL3 ZFHX2 ZFP62

6.10e-051101685fce7d5a0617fc664b657f5bb9abb290e7cc234cb
ToppCellMatrixFB-Fibroblast-A|MatrixFB / shred on cell class and cell subclass (v4)

MYO6 SYNM FREM1 PPP4R4 FAM171A1 COLEC12

6.30e-051801686adc64ad6033af705dd7b9163a83e20ef5c59f6eb
ToppCellChildren_(3_yrs)-Endothelial-endothelial_cell_of_vein-D139|Children_(3_yrs) / Lineage, Cell type, age group and donor

FAT4 ZNF423 FAM171A1 BMP6 PTPRR RAPGEF3

6.30e-05180168627e8bbee388e64dd79d70b160b76d45b1f398006
ToppCellfacs-Mammary_Gland-Mammary_Gland-18m-Mesenchymal|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

COL6A2 EMILIN2 LAMA4 ADAMTS5 COLEC12 GPNMB

6.90e-0518316865cfcd589a480e67654d3d94e71916f122150db10
ToppCellfacs-Mammary_Gland-Mammary_Gland-18m-Mesenchymal-stromal_cell|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

COL6A2 EMILIN2 LAMA4 ADAMTS5 COLEC12 GPNMB

6.90e-051831686c3ea8d3b916ffcaca3156e0d77a952724554c4ab
ToppCellfacs-Mammary_Gland-Mammary_Gland-18m-Mesenchymal-stromal_cell|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

COL6A2 EMILIN2 LAMA4 ADAMTS5 COLEC12 GPNMB

6.90e-05183168681003ddc24164959dd41bb12fcac72638789b8f2
ToppCellPCW_05-06-Neuronal-Neuronal_postreplicative-neuro_immature_neuronal_(2)|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung

PPM1E GRIK3 NEFM NLGN4X PTPRR MANEAL

6.90e-0518316869dfb398b9995d562864fe688861a831ada0814cd
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic-thymocyte|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FAT4 OBSCN GRIK3 FREM1 ZFHX4 UNC79

7.11e-0518416862cbed6462fea2622871bb7e49b0df3d984239281
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FAT4 OBSCN GRIK3 FREM1 ZFHX4 UNC79

7.11e-051841686ea7a7e2bac46d4d2c31a5d576b38a032b5335062
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic-proliferating_thymocyte;_DN_to_DP_transition,_dividing_(some_are_Cd8+/_Cd4+,_some_undergoing_VDJ_recombination)|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FAT4 OBSCN GRIK3 FREM1 ZFHX4 UNC79

7.11e-0518416862b19a8c5f823e00812908b23e66bb4e563278aff
ToppCellfacs-Mammary_Gland-Mammary_Gland-3m-Mesenchymal-stromal_cell|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

COL5A1 COL6A2 EMILIN2 LAMA4 ADAMTS5 COLEC12

7.33e-0518516863cd0686a14e734a0f243070ab939adcb4c454478
ToppCellfacs-Mammary_Gland-Mammary_Gland-3m-Mesenchymal-stromal_cell|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

COL5A1 COL6A2 EMILIN2 LAMA4 ADAMTS5 COLEC12

7.33e-05185168600258f458cbf6d36449db95528a6b5038d731d2d
ToppCellfacs-Mammary_Gland-Mammary_Gland-3m-Mesenchymal|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

COL5A1 COL6A2 EMILIN2 LAMA4 ADAMTS5 COLEC12

7.33e-051851686a94694e226856bc5b168464f52d76004145717a5
ToppCellBAL-Severe-Myeloid-Macrophage|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

UACA SDCCAG8 COLEC12 CYFIP1 GPNMB PLD2

7.33e-051851686ae966929fb5bbb08ffcbac76cb21941638727f55
ToppCellBAL-Severe-Myeloid-Macrophage-transitional_Macro-|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

UACA SDCCAG8 COLEC12 CYFIP1 GPNMB PLD2

7.33e-0518516863beebaa92275086b1fae5f8c0c3d54016c5ba2aa
ToppCelldroplet-Kidney-KIDNEY-1m-Mesenchymal-podocyte|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

COL6A2 SYNM APC2 GRIK3 ZNF35 ZFHX4

7.33e-051851686ca69499ba8c39b7ed6717d05685d6f70066a77bd
ToppCellBAL-Severe-Myeloid-Macrophage-transitional_Macro-|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

UACA SDCCAG8 COLEC12 CYFIP1 GPNMB PLD2

7.33e-051851686ceff11cfa679147ccfd0a0f8079e697a6bea34d9
ToppCellE17.5-Mesenchymal-mesenchymal_fibroblast-mesenchymal_alveolar_niche_cell|E17.5 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

COL5A1 COL6A2 PEG3 ADAMTS5 COLEC12 TRPM5

7.33e-051851686c85bba1210f1d389add3e40be9b96abac40cf8c1
ToppCellPCW_05-06-Neuronal-Neuronal_postreplicative|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung

PPM1E GRIK3 NEFM NLGN4X PTPRR MANEAL

7.33e-051851686512f489daeb3b72d4578dc6f4d0ebb5f38d5bbab
ToppCellBAL-Severe-Myeloid-Macrophage|Severe / Location, Disease Group, Cell group, Cell class (2021.03.09)

UACA SDCCAG8 COLEC12 CYFIP1 GPNMB PLD2

7.33e-0518516869aea5ed8f9cee5ee933891203aac7adb85d68201
ToppCellBAL-Severe-Myeloid-Macrophage-transitional_Macro|Severe / Location, Disease Group, Cell group, Cell class (2021.03.09)

UACA SDCCAG8 COLEC12 CYFIP1 GPNMB PLD2

7.33e-05185168642939b294ea3e871274d8b73124c850dc1904fd2
ToppCellSevere_COVID-19-Myeloid-transitional_Macro|Severe_COVID-19 / Disease group,lineage and cell class (2021.01.30)

UACA SDCCAG8 COLEC12 CYFIP1 GPNMB PLD2

7.33e-051851686f7ef0d7740b4cfedc38846e802898c402dc411fd
ToppCellBAL-Severe-Myeloid-Macrophage-transitional_Macro|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

UACA SDCCAG8 COLEC12 CYFIP1 GPNMB PLD2

7.33e-0518516867a3612520ae4f0cd61480eadba31eecce001419d
Diseaseisolated growth hormone deficiency type II (implicated_via_orthology)

CSH1 CSH2 CSHL1

1.64e-0651633DOID:0060872 (implicated_via_orthology)
DiseaseCystic kidney

FAT4 ANKS6 SDCCAG8

3.27e-0661633C0022679
Diseaseisolated growth hormone deficiency (implicated_via_orthology)

CSH1 CSH2 CSHL1

5.70e-0671633DOID:0060870 (implicated_via_orthology)
DiseaseCystic Kidney Diseases

FAT4 ANKS6 SDCCAG8

2.64e-05111633C1691228
Diseasecongenital hypothyroidism (biomarker_via_orthology)

CSH1 CSH2 CSHL1

5.76e-05141633DOID:0050328 (biomarker_via_orthology)
Diseaseoverall survival, response to antineoplastic agent

UACA WDR62

1.81e-0441632EFO_0000638, GO_0097327
Diseaseosteoporosis (biomarker_via_orthology)

CSH1 CSH2 CSHL1

2.36e-04221633DOID:11476 (biomarker_via_orthology)
Diseaseprostate cancer (is_marker_for)

MYO6 EZH2 BMP6 PIK3R1 PIK3R2 KDM6A

2.38e-041561636DOID:10283 (is_marker_for)
DiseaseLeukemia, Myelomonocytic, Chronic

EZH2 KDM6A

4.48e-0461632C0023480
DiseaseColorectal Carcinoma

APC2 PEG3 PPM1E OBSCN GALNT12 GRIK3 BMP6 NF1 NLGN4X OLFM2 GPNMB KDM6A

5.55e-0470216312C0009402
DiseaseNEPHRONOPHTHISIS 2

ANKS6 ZNF423

8.31e-0481632C1865872
DiseaseMalignant neoplasm of breast

ZSWIM5 APC2 PPM1E OBSCN GRIK3 TRAPPC8 EZH2 DYSF ZNF546 NF1 GPNMB PLD2 NIPBL MED12 GOLGB1

9.42e-04107416315C0006142
DiseaseDisorder of eye

PDE6C ZNF423 SDCCAG8 CDH23 PRPF8 FREM1

1.19e-032121636C0015397
Diseaseobesity (implicated_via_orthology)

FAT4 PLXNB2 BMP6 ZFHX4 ZFHX2 MED12

1.28e-032151636DOID:9970 (implicated_via_orthology)
Diseasetype 1 diabetes mellitus (implicated_via_orthology)

CSH1 CSH2 CSHL1

1.31e-03391633DOID:9744 (implicated_via_orthology)
Diseasebirth weight, pelvic organ prolapse

COL5A1 DOCK9 LAMA4

2.53e-03491633EFO_0004344, EFO_0004710
Diseaseocular hypertension, response to triamcinolone acetonide

CDH23 DDOST CFAP61

2.53e-03491633EFO_0006954, EFO_1001069
Diseasedevelopmental disorder of mental health (implicated_via_orthology)

TANC2 PLXNB2 TANC1

2.53e-03491633DOID:0060037 (implicated_via_orthology)
Diseasecongenital hypothyroidism (implicated_via_orthology)

DUOX2 NEFM

2.64e-03141632DOID:0050328 (implicated_via_orthology)
Diseasemalignant pleural mesothelioma (is_marker_for)

EZH2 KDM6A

2.64e-03141632DOID:7474 (is_marker_for)
Diseaseposterior thigh muscle volume

CSH1 CSHL1

3.04e-03151632EFO_0020931
DiseaseCardiovascular Abnormalities

ANKS6 APC2

3.46e-03161632C0243050
DiseaseSynostotic Posterior Plagiocephaly

EZH2 FREM1

3.46e-03161632C1833340
DiseaseCraniosynostosis, Type 1

EZH2 FREM1

3.46e-03161632C4551902
DiseaseAcrocephaly

EZH2 FREM1

3.46e-03161632C0030044
DiseaseTrigonocephaly

EZH2 FREM1

3.46e-03161632C0265535
DiseaseScaphycephaly

EZH2 FREM1

3.46e-03161632C0265534
DiseaseSynostotic Anterior Plagiocephaly

EZH2 FREM1

3.46e-03161632C2931150
DiseaseMetopic synostosis

EZH2 FREM1

3.46e-03161632C1860819
DiseaseBrachycephaly

EZH2 FREM1

3.91e-03171632C0221356
Diseaseapolipoprotein B measurement

ZNF180 GPS2 ZNF226 ZNF112 ZNF229 ZNF235 PPP4R4 SORT1 NF1 ANKDD1B

3.92e-0366316310EFO_0004615
Diseasecolon cancer (is_marker_for)

EZH2 NF1 PIK3R2

4.29e-03591633DOID:219 (is_marker_for)
Diseasecartilage thickness measurement

PIK3R1 DOT1L

4.38e-03181632EFO_0007873
Diseasebody composition measurement

DYSF BMP6 CSH1 CSHL1 PIK3R1

4.46e-031931635EFO_0005106
Diseaseneuropsychological test

FAT4 PPM1E FAM135B MANEAL ZNF197

4.86e-031971635EFO_0003926
DiseaseJuvenile Myelomonocytic Leukemia

EZH2 NF1

4.88e-03191632C0349639
DiseaseAPOE carrier status, dementia

GRIK3 FAM135B CEACAM21

4.93e-03621633EFO_0007659, MONDO_0001627
Diseaseunipolar depression, memory performance, cognitive function measurement

TRAPPC8 TEX26

5.40e-03201632EFO_0003761, EFO_0004874, EFO_0008354
DiseaseCraniosynostosis

EZH2 FREM1

5.40e-03201632C0010278
Diseasedilated cardiomyopathy

FMNL3 GPNMB

5.40e-03201632EFO_0000407

Protein segments in the cluster

PeptideGeneStartEntry
AVLLYHHVHSRLNSQ

AGBL5

331

Q8NDL9
QGSHTNIHLLVTTYN

ADNP

556

Q9H2P0
SEHHLQRAISAQQVY

EPC1

51

Q9H2F5
QYHHVSSRSLASLVL

CFAP61

356

Q8NHU2
LAQQLLHYHAIQAST

ALDH16A1

141

Q8IZ83
LHYHAIQASTQEEAL

ALDH16A1

146

Q8IZ83
LYSHASIENHIRLAV

ADAMTS5

301

Q9UNA0
YRNSQIEQASHHLRV

CEACAM21

126

Q3KPI0
YHIHQGLLLTTNQSL

GPR33

261

Q49SQ1
LFVSTNHTVNHTYVL

GPNMB

291

Q14956
YQQSLTVHTGTHLLS

GPS2

116

Q13227
LTNHYLHFLRIASSQ

FAT4

3726

Q6V0I7
LQAHRAHQLAIDTYQ

CSHL1

41

Q14406
LLRHILQQVYNHSVT

DOT1L

106

Q8TEK3
TLLASTHVNHNIYIT

AMBRA1

66

Q9C0C7
NSSHVLIVEAYNHDL

CDH23

1171

Q9H251
HQVLYNVTLFHVIST

OLFM2

436

O95897
VHQLFSQHYRATIGV

RAB32

46

Q13637
TYTATAIQNVVHRLF

ITGAX

226

P20702
VFNHAIRHTVYAALQ

CYFIP1

471

Q7L576
VYHISLVLTDSQNNR

DSG3

561

P32926
LTNVIHNLATYVFLH

ORMDL2

51

Q53FV1
NSTTVQYAGLLHHLT

DYNLRB2

36

Q8TF09
SNAHVRHSYIDLQRA

FAM171A1

716

Q5VUB5
SISLDYQHLRPQSIH

KIAA0100

446

Q14667
HSARQNIRHYLSEEL

MEPCE

481

Q7L2J0
QLRSAHETTHYYQLS

HIPK4

351

Q8NE63
SNYNTLRHLVAHLFR

GMIP

681

Q9P107
VRYYHQLSQHVTVDV

FUT4

371

P22083
INTSFHVLYEQSHLE

LIPT1

281

Q9Y234
TLSNAEIQFHIAHLY

KDM6A

201

O15550
ALTAQYTLLQNHHTA

CCDC88C

1131

Q9P219
LQAHRAHQLAIDTYQ

CSH2

41

P0DML3
HQDLVSVHIYVTQLA

DUOX2

1441

Q9NRD8
VHSFHSQLLTYAVNI

FSIP2

3071

Q5CZC0
SVQREQSLHSFHTLF

EZH2

271

Q15910
SQYLAQHEHLLLNTS

CBFA2T2

201

O43439
NSIFYEHLTRSLQHT

PCNX3

1341

Q9H6A9
HTDSLNTLVALHQLY

PLXNB2

1781

O15031
YNDRSVLENHHISSV

PDE1B

286

Q01064
YLNFVSIILRLHHTS

PDE6C

216

P51160
IISNISYTAHHLRTL

COLEC12

346

Q5KU26
SYTAHHLRTLTSNLN

COLEC12

351

Q5KU26
AFHINYVQSRHLRIE

FREM1

1101

Q5H8C1
FHTQSSVRHFALNVI

NIPBL

2291

Q6KC79
LSHYDQHQVTAQVSR

MED12

836

Q93074
VSTINHQALEQLHYV

GBP4

146

Q96PP9
HYVLQVVSQFHRLLQ

PGAP4

116

Q9BRR3
LHYQHTSLVQHNDSL

PIK3R1

696

P27986
HLYSSTQVSVRPLQH

DDOST

401

P39656
TTSNTLHYIHIEQLD

HUWE1

216

Q7Z6Z7
RQLTANTGHTIHVHY

HUWE1

2551

Q7Z6Z7
HRFLLLENVVSQYTH

IP6K3

196

Q96PC2
YIEHRSNETSVIHSL

PEG3

941

Q9GZU2
QIQETLQRQYSHHSS

NUP155

1156

O75694
LQRQYSHHSSVQDAV

NUP155

1161

O75694
YHSSSEAQVSKRHQI

PTPRR

66

Q15256
AIYASIHLHVNLVRQ

PPM1E

281

Q8WY54
LSATQYLHNQHILHL

OBSCN

7776

Q5VST9
LQTTRQELSHALYQH

PRPF19

96

Q9UMS4
YQHASLVQHNDALTV

PIK3R2

696

O00459
THVSFREHNLYTVNI

IL1RL2

286

Q9HB29
HLHNLNEIFQYVSTT

NLGN4Y

596

Q8NFZ3
SSLSALALHEHYVQQ

APC2

1276

O95996
HYSLEQVQADQISLH

KLHL22

221

Q53GT1
HLVSTVYTQDQHLHN

DOCK9

816

Q9BZ29
YQLLHHSANQLSITV

CRTAM

71

O95727
VSSVHHNSTLLRYSV

CERK

271

Q8TCT0
KETYENTSHQVHTLR

FMNL3

441

Q8IVF7
VEESIAHHYNNQIRT

COQ7

141

Q99807
HNLTAIHEALETTQY

COL6A2

896

P12110
TFLISIYQVLQEHQH

BMP6

271

P22004
HQINIYLSDRISLHR

GALNT12

101

Q8IXK2
GQSSQLIQHQRVHYR

GLI4

361

P10075
RQILQETIHNFHSSF

ANKS6

841

Q68DC2
LRLLSASAHQNVTYH

COL5A1

1731

P20908
LDTAHQYSIQVAFHI

MANEAL

211

Q5VSG8
LYSQLNHTENDVTHL

EMILIN2

611

Q9BXX0
TLHSQVTTYLTQEHH

FAM135B

326

Q49AJ0
NTTLTYDIQRIHFHD

GRIK3

76

Q13003
LQAHRAHQLAIDTYQ

CSH1

41

P0DML2
NYVETEQLIHVHNHT

INPP5F

306

Q9Y2H2
YQLRTHHLSQITEAA

DYSF

741

O75923
HLHNLNEIFQYVSTT

NLGN4X

596

Q8N0W4
LHSLYQARIVSHANT

FOCAD

1621

Q5VW36
HTHNTQLYLALNRDD

NUP210L

1421

Q5VU65
YVIFLHSLRNHSAEV

OR4C16

216

Q8NGL9
QTDLHAQSSEIRYNH

nan

51

A6NNC1
AAHRHVNEINATIYL

LAMA4

306

Q16363
LQRYTISSNPHFHVL

PCDHB6

166

Q9Y5E3
FYSSLNQTHTHTVLL

FBXL21P

26

Q9UKT6
RFLVHRYSVLQQHAE

SORT1

786

Q99523
RNVTHLYSTILGHQI

TMEM248

131

Q9NWD8
LLQHFIDHDITSQLY

TBC1D31

556

Q96DN5
SIHAYTHSFLQVILL

PPP4R4

126

Q6NUP7
STQYDLLHNHLTVRV

SYT17

191

Q9BSW7
NTQHLLDHLSIVYVA

TMEM131L

276

A2VDJ0
QRHQTTQQIVYHGLV

SYNM

1316

O15061
HDLVHTINDQSQYIH

SDCCAG8

116

Q86SQ7
QYLSHILEQRTSSNV

SEL1L2

46

Q5TEA6
QQHRQALESEYVSAH

NBEAL2

2261

Q6ZNJ1
TLQHRYSEHTQLQTQ

SMG1

2531

Q96Q15
EHLQFLLSSYQHVLR

SIMC1

771

Q8NDZ2
HAYVQHRVHSSQDIL

TANC1

661

Q9C0D5
QAYILHRIHSSSEIQ

TANC2

611

Q9HCD6
AIQASRISTYLHLHS

SLC41A2

426

Q96JW4
RITHVYNHSNSEITS

TENM2

2331

Q9NT68
TNIIFVAIHREHYTS

STEAP2

86

Q8NFT2
HFYSHIVSNDTTVIV

TECTB

96

Q96PL2
TLINLTNLTHLYLHN

OMG

186

P23515
LHFATQSNHVRIVEY

ANKDD1B

171

A6NHY2
YITRHSNLSEIHVAF

C12orf4

416

Q9NQ89
LTSAARLVNHTLYVH

COASY

26

Q13057
HETTGHTYERVLQQQ

C11orf52

46

Q96A22
ANLHLRTNHIYVSSD

PRPF8

2081

Q6P2Q9
TFSYLVQHQRIHTSE

ZNF30

271

P17039
SLFNSIHQVELIHYV

RAPGEF3

676

O95398
FSQSANLVVHQRIHT

ZNF35

231

P13682
FTQSANLIVHQRSHT

ZNF35

371

P13682
TQKNILLVHYNSVSH

ZFHX4

1506

Q86UP3
INAYINTTHSRLTHI

ZSWIM5

1116

Q9P217
SQSAYLLNHQRIHTG

ZNF197

436

O14709
TFAQTTYLIDHQRLH

ZNF197

546

O14709
VFSYRSNLIAHQRIH

ZNF197

826

O14709
FSQYSVLIQHQRIHT

ZNF250

516

P15622
QRIHNLTAYLQTLHR

VPS11

431

Q9H270
GLLQHQTTHSRQEYA

ZNF549

196

Q6P9A3
TFRLLSQLTQHQSIH

ZFP30

446

Q9Y2G7
QSSHLYQHQRIHTGE

ZNF3

351

P17036
TFYRNLTLHQSIHTD

ZNF573

536

Q86YE8
HNDRVQALSYAQHTR

WDFY2

241

Q96P53
FTQSTNLIQHQRVHT

ZNF287

741

Q9HBT7
FNQSSSLIIHQRIHT

ZSCAN20

996

P17040
TQKNILLVHYNSVSH

ZFHX2

1201

Q9C0A1
ITSHQHLLTVYDFEQ

TRPM5

306

Q9NZQ8
QLYVLFLRHHSRTSN

RMC1

221

Q96DM3
KHIQHQTIHIRENSY

ZNF267

281

Q14586
SISYDTNLQTHQRIH

ZNF75CP

356

Q92670
FRQQSYLIQHLRIHT

ZNF546

226

Q86UE3
VQSSDLTSHQRIHNY

ZNF322

81

Q6U7Q0
FHYVLVNSLHRIITN

NF1

406

P21359
FNESSYLISHQRTHT

ZNF200

261

P98182
YSSVLQVHQRLHTGE

ZNF229

416

Q9UJW7
FRYNSLLLRHQIIHT

ZNF517

186

Q6ZMY9
QHQEVIAIYRTHLLS

UACA

1376

Q9BZF9
SQSSYLQIHQKAHSI

ZNF226

541

Q9NYT6
IVRIFQAHSLHYLAN

WDR62

316

O43379
FRQSYKLIAHQRTHT

ZNF180

446

Q9UJW8
FSQSYVLVVHQRTHT

ZNF180

586

Q9UJW8
NYSSLLHIHQNIERE

ZNF112

296

Q9UJU3
NQNSYLIIHQRIHTG

ZNF852

421

Q6ZMS4
SFTQNYDLLRHERLH

ZNF496

561

Q96IT1
AFSLRAYLTVHQRIH

ZNF570

366

Q96NI8
QSYDLVIHQRTHTGE

ZNF544

391

Q6NX49
FSYHSALIIHQRIHT

ZNF879

381

B4DU55
NQASYLTRHQIIHTG

ZNF528

531

Q3MIS6
FNYTSLLSQHRRVHT

ZFP62

626

Q8NB50
LSQEQHRIQHNSDYS

TRAPPC8

166

Q9Y2L5
AVHNQSHVRELLAQY

SUOX

141

P51687
FRLLSQLTQHQSIHT

ZFP14

461

Q9HCL3
LYSFLTQHQRIHTGE

ZFP14

491

Q9HCL3
SQLIFHQRTHTGETY

ZNF18

421

P17022
VPSVLHSYLRNQEHT

TEX26

216

Q8N6G2
FDSQESLLQHLTVHY

ZNF423

671

Q2M1K9
TYRVHVAQQQDVHLT

TMEM129

176

A0AVI4
SFSQSTYLIEHQRLH

ZFP2

306

Q6ZN57
FSQSAYLIEHQRIHT

ZFP2

391

Q6ZN57
YDTNTENILHTLTQH

WDSUB1

266

Q8N9V3
ENILHTLTQHTRYVT

WDSUB1

271

Q8N9V3
SFIRSSSLIRHYQIH

ZNF623

271

O75123
YTHQSQLTEHLRLHS

ZNF425

591

Q6IV72
SILNAYLHTIRESQH

PLD2

621

O14939
FSQRSNLQVHQIIHT

ZNF235

636

Q14590
HAFQTLTHIYNKVRT

UGGT1

566

Q9NYU2
VFSRNSYLVQHLIIH

ZNF83

241

P51522
AFSQSTYLIQHRRIH

ZNF34

511

Q8IZ26
SQLIQHQRIHTEERY

ZFP3

266

Q96NJ6
LHLIHITVNTLNAQY

UNC79

1421

Q9P2D8
SQLEETRHLYHSSQN

GOLGB1

2291

Q14789
TVYSHLFDHVVNRVN

MYO6

426

Q9UM54
LSVSHAQQEYLENHI

MYZAP

136

P0CAP1
RHNHDLSSYQDTIQQ

NEFM

351

P07197