Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyBiologicalProcessheparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process

NDST4 EXT2

3.62e-058242GO:0015014
GeneOntologyBiologicalProcessheparin biosynthetic process

NDST4 EXT2

7.09e-0511242GO:0030210
GeneOntologyBiologicalProcessglycosaminoglycan biosynthetic process

NDST4 B3GNT7 EXT2

9.20e-0576243GO:0006024
GeneOntologyBiologicalProcessaminoglycan biosynthetic process

NDST4 B3GNT7 EXT2

1.07e-0480243GO:0006023
GeneOntologyBiologicalProcessprotein localization to kinetochore

CHAMP1 TTK

1.54e-0416242GO:0034501
GeneOntologyBiologicalProcessprotein localization to condensed chromosome

CHAMP1 TTK

1.54e-0416242GO:1903083
GeneOntologyBiologicalProcessheparin metabolic process

NDST4 EXT2

1.75e-0417242GO:0030202
GeneOntologyBiologicalProcessmucopolysaccharide metabolic process

NDST4 B3GNT7 EXT2

2.08e-04100243GO:1903510
GeneOntologyBiologicalProcessglycosaminoglycan metabolic process

NDST4 B3GNT7 EXT2

3.64e-04121243GO:0030203
GeneOntologyBiologicalProcessaminoglycan metabolic process

NDST4 B3GNT7 EXT2

4.70e-04132243GO:0006022
GeneOntologyBiologicalProcessregulation of synapse maturation

ADGRB3 RELN

5.91e-0431242GO:0090128
GeneOntologyBiologicalProcessheparan sulfate proteoglycan biosynthetic process

NDST4 EXT2

7.54e-0435242GO:0015012
GeneOntologyBiologicalProcessprotein localization to chromosome, centromeric region

CHAMP1 TTK

1.09e-0342242GO:0071459
GeneOntologyBiologicalProcesssulfur compound biosynthetic process

NDST4 B3GNT7 EXT2

1.12e-03178243GO:0044272
GeneOntologyCellularComponentkinetochore

KIF18A CHAMP1 BOD1L2 TTK

5.05e-05181244GO:0000776
GeneOntologyCellularComponentcondensed chromosome, centromeric region

KIF18A CHAMP1 BOD1L2 TTK

6.48e-05193244GO:0000779
GeneOntologyCellularComponentchromosomal region

KIF18A CHAMP1 BOD1L2 TTK SMG6

1.00e-04421245GO:0098687
GeneOntologyCellularComponentspindle

CEP170 KIF18A CHAMP1 BOD1L2 TTK

1.70e-04471245GO:0005819
GeneOntologyCellularComponentchromosome, centromeric region

KIF18A CHAMP1 BOD1L2 TTK

2.57e-04276244GO:0000775
GeneOntologyCellularComponentcondensed chromosome

KIF18A CHAMP1 BOD1L2 TTK

3.84e-04307244GO:0000793
DomainDnaJ

DNAJC13 DNAJA2

1.87e-0348252PF00226
DomainDnaJ

DNAJC13 DNAJA2

1.95e-0349252SM00271
DomainDNAJ_1

DNAJC13 DNAJA2

1.95e-0349252PS00636
DomainDNAJ_2

DNAJC13 DNAJA2

1.95e-0349252PS50076
Domain-

DNAJC13 DNAJA2

1.95e-03492521.10.287.110
DomainDnaJ_domain

DNAJC13 DNAJA2

2.11e-0351252IPR001623
PathwayKEGG_MEDICUS_REFERENCE_HEPARAN_SULFATE_BIOSYNTHESIS

NDST4 EXT2

8.41e-0511182M47921
PathwayREACTOME_GLYCOSAMINOGLYCAN_METABOLISM

NDST4 B3GNT7 EXT2

4.81e-04123183MM14623
PathwayKEGG_GLYCOSAMINOGLYCAN_BIOSYNTHESIS_HEPARAN_SULFATE

NDST4 EXT2

4.91e-0426182M7330
PathwayREACTOME_GLYCOSAMINOGLYCAN_METABOLISM

NDST4 B3GNT7 EXT2

5.16e-04126183M695
PathwayREACTOME_HS_GAG_BIOSYNTHESIS

NDST4 EXT2

6.13e-0429182MM14802
PathwayREACTOME_HS_GAG_BIOSYNTHESIS

NDST4 EXT2

7.01e-0431182M685
PathwayWP_GLYCOSAMINOGLYCAN_SYNTHESIS_IN_FIBROBLASTS

NDST4 EXT2

1.23e-0341182M48095
PathwayREACTOME_HEPARAN_SULFATE_HEPARIN_HS_GAG_METABOLISM

NDST4 EXT2

2.12e-0354182MM14633
PathwayWP_11P112_COPY_NUMBER_VARIATION_SYNDROME

B3GNT7 EXT2

2.28e-0356182M48075
PathwayREACTOME_HEPARAN_SULFATE_HEPARIN_HS_GAG_METABOLISM

NDST4 EXT2

2.36e-0357182M692
Pubmed

Ubiquitin ligase Ufd2 is required for efficient degradation of Mps1 kinase.

UBE4B TTK

1.49e-06325222045814
Pubmed

Spatiotemporal profile of postsynaptic interactomes integrates components of complex brain disorders.

ADGRB3 CEP170 DNAJC13 LRCH2 BCOR DNAJA2 SMG6

3.79e-0696325728671696
Pubmed

An organelle-specific protein landscape identifies novel diseases and molecular mechanisms.

CEP170 PTOV1 BBS1 KIF18A DNAJC13 LRCH2 ARID3B

2.96e-05132125727173435
Pubmed

Interaction proteome of human Hippo signaling: modular control of the co-activator YAP1.

PTOV1 KIF18A LRCH2 DNAJA2

3.95e-0527025424366813
Pubmed

Absence of layer-specific cadherin expression profiles in the neocortex of the reeler mutant mouse.

PCDH11X RELN

4.49e-051425220847152
Pubmed

High-resolution photocatalytic mapping of SARS-CoV-2 spike interactions on the cell surface.

PTOV1 KIF18A DNAJA2 SMG6

6.51e-0530725437499664
Pubmed

Systematic bromodomain protein screens identify homologous recombination and R-loop suppression pathways involved in genome integrity.

CEP170 MMP21 BCOR CHAMP1 BOD1L2 DNAJA2

1.13e-04111625631753913
Pubmed

BCOR modulates transcriptional activity of a subset of glucocorticoid receptor target genes involved in cell growth and mobility.

BCOR ARID3B

1.36e-042425233722704
Pubmed

The E3 ubiquitin ligase HECTD1 contributes to cell proliferation through an effect on mitosis.

CEP170 KIF18A DNAJC13 DNAJA2 ARID3B

1.81e-0475925535915203
Pubmed

The cell proliferation antigen Ki-67 organises heterochromatin.

KIF18A CHAMP1 DNAJA2 ARID3B

1.98e-0441025426949251
Pubmed

Identification of proximal SUMO-dependent interactors using SUMO-ID.

CEP170 KIF18A BCOR ARID3B

2.68e-0444425434795231
Pubmed

A genome-wide association study (GWAS) for bronchopulmonary dysplasia.

NDST4 CEP170

2.74e-043425223897914
Pubmed

Oct4 links multiple epigenetic pathways to the pluripotency network.

DNAJC13 DNAJA2 ARID3B

4.10e-0420325322083510
Pubmed

The Dual Estrogen Receptor α Inhibitory Effects of the Tissue-Selective Estrogen Complex for Endometrial and Breast Safety.

BCOR TTK

4.40e-044325226487511
Pubmed

Prediction of the coding sequences of mouse homologues of KIAA gene: III. the complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.

ADGRB3 BCOR CHAMP1 SMG6

5.19e-0452925414621295
Pubmed

Comprehensive Interactome Mapping of the DNA Repair Scaffold SLX4 Using Proximity Labeling and Affinity Purification.

KIF18A CHAMP1 ARID3B

5.32e-0422225337071664
Pubmed

Genome-wide CRISPR screen identifies HNRNPL as a prostate cancer dependency regulating RNA splicing.

CEP170 PRUNE2 DNAJC13 SLC8B1 UBE4B SMG6

5.35e-04148925628611215
Pubmed

Construction of expression-ready cDNA clones for KIAA genes: manual curation of 330 KIAA cDNA clones.

ADGRB3 PRUNE2 SMG6

5.53e-0422525312168954
Pubmed

SRCAP complex promotes lung cancer progression by reprograming the oncogenic transcription of Hippo-YAP/TAZ signaling pathway.

CEP170 BCOR CHAMP1 ARID3B

5.97e-0454925438280479
Pubmed

Human Immunodeficiency Virus Type 1 Vpr Mediates Degradation of APC1, a Scaffolding Component of the Anaphase-Promoting Complex/Cyclosome.

CEP170 BCOR TTK

6.83e-0424225334011540
GeneFamilyDNAJ (HSP40) heat shock proteins|C2 tensin-type domain containing

DNAJC13 DNAJA2

1.07e-0349182584
GeneFamilyArmadillo repeat containing|Protein phosphatase 1 regulatory subunits

PCDH11X KIF18A

1.37e-02181182694
GeneFamilyAnkyrin repeat domain containing

BCOR GPANK1

2.37e-02242182403
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial-Ascending_Vasa_Recta_Endothelial_Cell_prolif|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

ADGRB3 SELP RELN

1.05e-041652536a621b300442c52adfc15b61d3a6d3a3cb00099f
ToppCellEndothelial-B-Donor_04|World / lung cells shred on cell class, cell subclass, sample id

PCDH11X RELN LRCH2

1.09e-041672536a03d16165e0b003092c39972928981abd4a75aa
ToppCelldroplet-Lung-nan-18m-Lymphocytic-Proliferating_NK|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

KIF18A CHAMP1 TTK

1.19e-04172253e495efd25aec60b97ac2b5aa861651bd73174a17
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial-Ascending_Vasa_Recta_Endothelial_Cell_prolif|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

ADGRB3 SELP RELN

1.19e-04172253c056d44e2e130ceccadfcdceb192a7f095d779c8
ToppCelldroplet-Lung-nan-18m-Myeloid-Proliferating_Alveolar_Macrophage|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PRUNE2 KIF18A B3GNT7

1.36e-0418025343fd5c498a87bb078d101298b472656f3294686a
ToppCellfacs-Heart-LV-18m-Lymphocytic-B_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

KIF18A B3GNT7 ARID3B

1.38e-041812538855812c85ef45c1be6bd511619b2dfe5e441264
ToppCellEndothelial-B-IPF_02|World / lung cells shred on cell class, cell subclass, sample id

PRUNE2 KIF18A RELN

1.38e-041812534fe0215d08f03d4e24749d70fce01b7aa22906fd
ToppCellfacs-Heart-LV-18m-Lymphocytic-B_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

KIF18A B3GNT7 ARID3B

1.38e-0418125357f82f54e20e19aa17a2ea22af22e3bc8965d622
ToppCellfacs-Heart-LV-18m-Lymphocytic|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

KIF18A B3GNT7 ARID3B

1.40e-04182253d0d18dd5d8b2d21e42c3c4259f824c91f24a54bc
ToppCelldroplet-Lung-18m-Hematologic-myeloid-alveolar_macrophage-proliferating_alveolar_macrophage|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

PRUNE2 KIF18A B3GNT7

1.43e-04183253e91f00b75d43ee6293fdd4a129b789cd95f8d11a
ToppCellfacs-Marrow-T-cells-3m-Lymphocytic-late_pro-B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PCDH11X KIF18A TTK

1.50e-041862533993f1ef8a33b8a75dfd3db8d4845b5afbb0bb3d
ToppCellfacs-Marrow-T-cells-3m-Lymphocytic-late_pro_B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PCDH11X KIF18A TTK

1.50e-04186253ec6d0c29e196e374baa96dd3d506f489c959e77e
ToppCellfacs-Brain_Non-Myeloid-Cortex-3m-Epithelial-nan|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

KIF18A B3GNT7 TTK

1.52e-0418725338ee33295a21db4aae5ba085df033db9693e41c6
ToppCellLV-10._Endothelium_II|World / Chamber and Cluster_Paper

PCDH11X SELP BCOR

1.52e-041872537876dcb4800c2e54874df3d933efb79307a64a97
ToppCellfacs-Brain_Non-Myeloid-Cortex-3m-Epithelial|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

KIF18A B3GNT7 TTK

1.52e-04187253dbcec24d2c852964736c78e9d81650bff5c455ae
ToppCellfacs-Brain_Non-Myeloid-Cortex-3m-Epithelial-neuronal_stem_cell|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

KIF18A B3GNT7 TTK

1.52e-04187253a2076599b33ae6750961b573bfebcb9036fa4ee8
ToppCellILEUM-non-inflamed-(7)_Endothelial_cell-(7)_Lymphatics|(7)_Endothelial_cell / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)

PRUNE2 RELN B3GNT7

1.59e-041902539ce301841ce9486701fa28eb2a9929e35d476878
ToppCellfacs-Marrow-KLS-18m-Hematologic-hematopoietic_stem_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SELP PTOV1 EXT2

1.59e-0419025311f32f46661e44770782b8ec13c00028e1dfc3cd
ToppCellfacs-Marrow-KLS-18m-Hematologic-MPP_Fraction_A_+_HSC|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SELP PTOV1 PRUNE2

1.59e-0419025396a9756cad5468a12591021e6d661ed269b5b3d9
ToppCellfacs-Marrow-KLS-18m-Hematologic|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SELP PTOV1 EXT2

1.59e-0419025320f4f6fe09345878484086047061d6f900f9d476
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial-Ascending_Vasa_Recta_Endothelial_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

ADGRB3 SELP RELN

1.62e-04191253f663131a4810584c5854bd64ee7991a237b7707f
ToppCellfacs-Marrow-KLS-18m|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SELP PTOV1 EXT2

1.62e-0419125351327ba28b2e3052087fa0fc9b7c0339dc09a1e3
ToppCell368C-Endothelial_cells-Endothelial-F_(Lymphatics)|Endothelial_cells / Donor, Lineage, Cell class and subclass (all cells)

PRUNE2 RELN B3GNT7

1.64e-04192253b016e229300c183e14c0e2bba494bf49c7899112
ToppCellAnterior_Cingulate_gyrus_(CgG)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_SST|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

PCDH11X NDST4 RELN

1.64e-04192253dc40ef2341e5d6a6d479f140e023fe1bf687928d
ToppCellNeuron-Postmitotic-Excitatory_Neuron_-Deep_Layer-27|World / Primary Cells by Cluster

NDST4 PTOV1 RELN

1.64e-04192253cf989f26c0ebdc0cd12e1e41958f063e4fa3e468
ToppCell368C-Endothelial_cells-Endothelial-F_(Lymphatics)-|Endothelial_cells / Donor, Lineage, Cell class and subclass (all cells)

PRUNE2 RELN B3GNT7

1.64e-04192253ac96831492c62ad9e1f7d0b764fbdf7d8a189ad9
ToppCell10x_3'_v2v3-Neoplastic-Stem-like-NPC-like-NPC-like_Prolif-D|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

PCDH11X KIF18A TTK

1.64e-04192253f518839ecd9377537a414e8798766f7d91eafeac
ToppCellSmart-start-Cell-Wel_seq-Neoplastic-Stem-like-NPC-like-NPC-like_Prolif-D|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

PCDH11X KIF18A TTK

1.64e-0419225390d25b0b38f1cd7a98c76c1f9e38166da6d7a316
ToppCellMid-temporal_gyrus_(MTG)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_SST|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

PCDH11X NDST4 RELN

1.67e-041932532189da4b727e25e62669d7b9257f06493be21a27
ToppCellPrimary_Motor_Cortex_(M1)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_SST|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

PCDH11X NDST4 RELN

1.67e-04193253010717ca052b6c8a525a43aaeffddea0d1113e63
ToppCellFetal_brain-fetalBrain_Zhong_nature-GW26-Stem_cells|GW26 / Sample Type, Dataset, Time_group, and Cell type.

NDST4 KIF18A TTK

1.67e-041932533091090abcf18b48eac7e6c85653c18aa54fcb9b
ToppCellFetal_brain-fetalBrain_Zhong_nature-GW26-Stem_cells-Stem_cells|GW26 / Sample Type, Dataset, Time_group, and Cell type.

NDST4 KIF18A TTK

1.67e-04193253a18770ceb770aaa4903dd04442ad0a73159ead9a
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial-Ascending_Vasa_Recta_Endothelial_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

ADGRB3 SELP RELN

1.69e-04194253cf9cf115dbbb9997f7c303ae07f42f3d80ff9a21
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial-Ascending_Vasa_Recta_Endothelial_Cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

ADGRB3 SELP RELN

1.69e-04194253fa6d51f36a3dae8763a595c20892987ed454c0f0
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial-Ascending_Vasa_Recta_Endothelial_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

ADGRB3 SELP RELN

1.69e-04194253b490fffc94f005dff9a34ce34d80ca776e3a1387
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial-Ascending_Vasa_Recta_Endothelial_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

ADGRB3 SELP RELN

1.69e-04194253ad6c04ad0621689e3bf4c94ccd6e60653bbd02c7
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Endothelial|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

ADGRB3 SELP RELN

1.74e-0419625348b4a9cea97a55190217deaf51bf867608c5a9a7
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

ADGRB3 SELP RELN

1.74e-041962538f2031b1a9232c389517fbf3c29f47f9468b0077
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Endothelial-blood_vessel_endothelial_cell_of_kidney|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

ADGRB3 SELP RELN

1.74e-04196253473980c827443464d08a0be28c53e3536369b12a
ToppCellControl-Control-Myeloid-immature_Neutrophil|Control / Disease, condition lineage and cell class

KIF18A SLC8B1 TTK

1.85e-04200253118321ac443feb42aee171baccfc4610f00a8822
ToppCellprimary_visual_cortex-Neuronal-GABAergic_neuron-Sst-Sst_Tac1_Tacr3|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

PCDH11X NDST4

1.68e-0310925292ab514fd8d6711f55de9671fc80da22b20ad248
ToppCellfrontal_cortex-Neuronal-GABAergic_neuron-Sst-Sst_Hpse_Cbln4|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

PCDH11X RELN

1.87e-03115252ac73aa06e617ed791c6ae9e38189bac74188c27b
ToppCellCOVID-19-kidney-Epithelial_(Imm)|COVID-19 / Disease (COVID-19 only), tissue and cell type

NDST4 PRUNE2

2.00e-031192527cde7c73bb71f5e1911706e51c2ea6dcc72930ac
ToppCellfrontal_cortex-Neuronal-GABAergic_neuron-Lamp5-Lamp5_Fam19a1_Pax6|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

NDST4 RELN

2.07e-031212527f2057367777c6c92f596054cbc5fe567d079fbc
ToppCellCOVID-19-kidney-Mito-rich_Int|COVID-19 / Disease (COVID-19 only), tissue and cell type

NDST4 RELN

2.10e-03122252a4220adb4e6055a599bd9bbf65d460fc4e68b543
ToppCellprimary_visual_cortex-Neuronal-GABAergic_neuron-Lamp5-Lamp5_Fam19a1_Tmem182|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

NDST4 RELN

2.17e-03124252690595d710b57b7cff8029a3bb06a8dd7e3c03c1
ToppCellprimary_visual_cortex-Neuronal-GABAergic_neuron-Sst-Sst_Hpse_Cbln4|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

PCDH11X RELN

2.24e-0312625294bd9cfe982b41a3114885173eab55feb0fbbbae
ToppCellfrontal_cortex-Neuronal-GABAergic_neuron-Lamp5-Lamp5_Fam19a1_Tmem182|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

NDST4 RELN

2.38e-031302528bd038b0423960ffdc6c8b128c46a55386f9c58c
ToppCellHippocampus-Macroglia-POLYDENDROCYTE-P5-P5_1-Sox4-POLYDENDROCYTE_(Neurogenesis.Sox4.Cdc20)|Hippocampus / BrainAtlas - Mouse McCarroll V32

KIF18A TTK

2.42e-03131252f9fb8d74ca720b81fd5910cc975510359a8ef751
ToppCellLPS-antiTNF-Unknown-Endothelial-Pericyte_2|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

KIF18A TTK

2.45e-0313225202491930097b75aaeedab9e8200711b0dc610944
ToppCellCOVID-19-kidney-Technical/muscle_(EC)|kidney / Disease (COVID-19 only), tissue and cell type

ADGRB3 RELN

2.71e-0313925264c35411bbe67acb5010dadc4b0b1be0f8b17737
ToppCellmetastatic_Lymph_Node-Myeloid_cells-Alveolar_Mac|Myeloid_cells / Location, Cell class and cell subclass

ADGRB3 MMP21

2.79e-03141252399380de5ea09e22fd128e3e55fffeffc4874c15
ToppCell356C-Fibroblasts-Fibroblast-C_(Myofibroblast)|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)

PCDH11X SELP

2.83e-031422527b6678a73d04feac12bbc909f2df478215511de0
ToppCell356C-Fibroblasts-Fibroblast-C_(Myofibroblast)-|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)

PCDH11X SELP

2.83e-03142252347f5832a86f4e41752e36e3e737df7ca6f79e90
ToppCellLPS-antiTNF-Myeloid-Myeloid_granulocytic|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

ADGRB3 SLC8B1

2.87e-031432524a0f26eef935fe68a1da5d319503059a8a8682dd
ToppCellLPS-antiTNF-Myeloid-Myeloid_granulocytic-Neutrophils|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

ADGRB3 SLC8B1

2.87e-0314325265328a0a2f3972fac596e07933e74b2ef7cceb84
ToppCellprimary_visual_cortex-Neuronal-GABAergic_neuron-Sst-Sst_Tac2_Tacstd2|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

PCDH11X RELN

2.87e-0314325224fd24846fbef049af669a57d42fcc18928d2b27
ToppCellAdult-Immune-dendritic_cell-D231|Adult / Lineage, Cell type, age group and donor

NDST4 TTK

3.03e-031472527cc4f74dd7a86247db8dc049ed7eadeb53825a96
ToppCellfrontal_cortex-Neuronal-GABAergic_neuron-Lamp5-Lamp5_Ntn1_Npy2r|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

NDST4 RELN

3.07e-031482525e738522d4ad35e08bc4ff8c41b7bea38ec6ef95
ToppCellCOVID-19-kidney-Technical/muscle_(Mes)|COVID-19 / Disease (COVID-19 only), tissue and cell type

NDST4 RELN

3.07e-03148252d6ac5972267254651dfbe16bb4e9a62228093cc7
ToppCellHippocampus-Macroglia-POLYDENDROCYTE-P5-P5_1|Hippocampus / BrainAtlas - Mouse McCarroll V32

KIF18A TTK

3.07e-03148252b9d3421c2eb8e748e9508c1cbd1cb4f96e23db5a
ToppCellHippocampus-Macroglia-POLYDENDROCYTE-P5-P5_1-Sox4|Hippocampus / BrainAtlas - Mouse McCarroll V32

KIF18A TTK

3.07e-031482522a7671dc27afbdf6a92d976c5f2b728bd18dd609
ToppCellRV-16._Neuronal|World / Chamber and Cluster_Paper

ADGRB3 RELN

3.11e-031492523a2f8c4173dcf9e3f8d3b8ffddbc597098adf7a9
ToppCellsevere_COVID-19-Treg|severe_COVID-19 / disease group, cell group and cell class (v2)

PCDH11X SLC8B1

3.19e-03151252bef8f31d5c4345a346fcf15db0fa36265ac304e7
ToppCellprimary_visual_cortex-Neuronal-GABAergic_neuron-Lamp5-Lamp5_Ntn1_Npy2r|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

NDST4 RELN

3.23e-031522528ff5a178a8f3550d89a003c0858820aab3773386
ToppCellprimary_visual_cortex-Neuronal-GABAergic_neuron-Lamp5-Lamp5_Plch2_Dock5|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

NDST4 RELN

3.23e-03152252fed80b467ec9e30c7f98bed6cc4f8c583b715e9e
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Proximal_Tubule_Epithelial_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

PRUNE2 BBS1

3.27e-03153252499670e716fc85ce76630fc813cec86f8419f2a1
ToppCell356C-Lymphocytic-CD4_T-cell-Treg_cell_4|356C / Donor, Lineage, Cell class and subclass (all cells)

PCDH11X SELP

3.27e-03153252cda759ab83a271974651fe4faa21ed4f7ecbb3ae
ToppCellRV-16._Neuronal|RV / Chamber and Cluster_Paper

ADGRB3 RELN

3.27e-03153252bed8bbf5c5cbfbf46a816066da472c3fdddecb5d
ToppCell356C-Lymphocytic-CD4_T-cell-Treg_cell_4|CD4_T-cell / Donor, Lineage, Cell class and subclass (all cells)

PCDH11X SELP

3.32e-031542521f8d127b657976656e4ec292f26d619943533b86
ToppCellIIH-CD8-exh_CD4|IIH / Condition, Cell_class and T cell subcluster

KIF18A CHAMP1

3.32e-03154252a2f51a3c5455fe2483e438375ea856afce8262fe
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial-Ascending_Vasa_Recta_Endothelial_Cell_prolif|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

ADGRB3 SELP

3.36e-03155252babcb9e548f04ace8157d506d27c5941c692c491
ToppCellmetastatic_Lymph_Node-Myeloid_cells-Alveolar_Mac|metastatic_Lymph_Node / Location, Cell class and cell subclass

ADGRB3 MMP21

3.36e-0315525203fd443740272dcb547e39deaf7ae89b8307f241
ToppCellprimary_visual_cortex-Neuronal-GABAergic_neuron-Sst-Sst_Hpse_Sema3c|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

PCDH11X RELN

3.36e-031552525c7b68b59244525e3714806c205a57a2daebf423
ToppCellTCGA-Kidney-Primary_Tumor-Renal_Cell_Carcinoma-Kidney_Clear_Cell_Renal_Carcinoma-6|TCGA-Kidney / Sample_Type by Project: Shred V9

KIF18A TTK

3.40e-03156252d249747c7108a0edfc72d24c09b0b0e4ed662b40
ToppCellPND03-Immune-Immune_Myeloid-DC-cDC1-cDC1_prolif|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

NDST4 SLC8B1

3.40e-03156252af47a4b17342bdb3cb62d7e2d52a81168e588629
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell-Peritubular_Capilary_Endothelial_Cell__prolif|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

ADGRB3 SELP

3.40e-03156252f894fac4e44a23718b20ad80c9677bf4f2118002
ToppCellPND01-Mesenchymal-Mesenchymal_structural-Fibroblastic-AF1-AF1_prolif|PND01 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

ADGRB3 CHAMP1

3.40e-03156252895927228c93cd090303984c5be6ebfb59ed6f3a
ToppCellsaliva-Severe-critical_progression_d12-22_with-steroid-Myeloid-Macrophage-macrophage,_alveolar-Macro_c1-C1QC|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)

EXT2 BCOR

3.40e-03156252abea3c183d32062b009a79a2bdf861021989c7ef
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell-Cycling_Endothelial_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

KIF18A TTK

3.40e-03156252b3f10cd044f24807576e7d56e51df7064dbf6c50
ToppCell5'-GW_trimst-1.5-LargeIntestine-Mesenchymal-fibroblastic-Stromal_3_(KCNN3+)|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

NDST4 MMP21

3.44e-03157252beab0ac47202266b04543c02cfcdda012375e879
ToppCellfrontal_cortex-Neuronal-GABAergic_neuron-Lamp5-Lamp5_Plch2_Dock5|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

NDST4 RELN

3.44e-03157252516903469756c5fabfdf56d7bd59b3bdd7b44e39
ToppCellPND28-Immune-Immune_Myeloid-Monocytic-Macrophage-AM-AM_mature|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

MMP21 B3GNT7

3.49e-031582526811dc4f101dfa9a9cc13d949760d43aa522bf3b
ToppCellCOVID-19-kidney-Technical/muscle_(Mes)|kidney / Disease (COVID-19 only), tissue and cell type

NDST4 RELN

3.53e-031592525335cbcdeaf2bbd0268bbfe0e45c8c0d288e640d
ToppCell356C-Myeloid-Macrophage-FABP4+_Macrophage|356C / Donor, Lineage, Cell class and subclass (all cells)

CEP170 PRUNE2

3.53e-0315925224f87c666eff10c1844c900ffd7ad49fa9f80481
ToppCellprimary_visual_cortex-Neuronal-GABAergic_neuron-Sst-Sst_Calb2_Pdlim5|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

PCDH11X RELN

3.57e-03160252dd16ca90feb3ae88b6409d6c278b4765da565514
ToppCell356C-Lymphocytic-CD4_T-cell-Treg_cell_4|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)

PCDH11X SELP

3.57e-03160252c2b5fadb4bac17fafc08831f6d3f4ff96ada7e70
ToppCellPND01-03-samps-Myeloid-Macrophage-macrophage-A|PND01-03-samps / Age Group, Lineage, Cell class and subclass

PRUNE2 B3GNT7

3.62e-031612525925ee646aa040550e3f8a164a13c8a5c0353319
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Endothelial-lymphatic_endothelial_cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

RELN LRCH2

3.62e-03161252fb59d96c2aa9e4654f02bf6ce36bf832776cb4dd
ToppCellPND03-Immune-Immune_Myeloid-DC-cDC1|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

NDST4 SLC8B1

3.62e-031612520e2b54a63781397f6b99eb0e201fbb820cbd7cc6
ToppCellfrontal_cortex-Neuronal-GABAergic_neuron-Sst-Sst_Calb2_Pdlim5|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

PCDH11X RELN

3.62e-03161252bf70be1de418615b5442ec684552551edaf1f072
ToppCellLeuk-UTI-Myeloid-tDC|Leuk-UTI / Disease, Lineage and Cell Type

B3GNT7 TTK

3.62e-0316125251b9f60986ed2e8e2297d31c80462c3ab65a2e5e
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Endothelial-lymphatic_endothelial_cell-lymphatic_endothelial_cell_of_renal_cortex|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

RELN LRCH2

3.62e-03161252c53c461fc721a7960cef86662f49e2a495520701
ToppCell390C-Lymphocytic-NK_cells-NK_cell_D3|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)

SELP BBS1

3.62e-031612523e5a125a25d55bf27652f456239b00b315d54d91
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Endothelial-lymphatic_endothelial_cell-lymphatic_endothelial_cell_of_renal_cortex-lymphatic_endothelial_cell_of_renal_cortex|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

RELN LRCH2

3.66e-031622522ac02523348660e514d464f8f2434ee0c312d784
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Neural-neural_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

ADGRB3 RELN

3.66e-03162252d28b2ea1d2c8f3c6a107991573471b6d0c49c4ae
ToppCellPrimary_Visual_cortex_(V1C)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_PVALB_1-Inh_L1-3_PVALB_WFDC2|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

NDST4 TTK

3.66e-03162252164ee1d0543c202831bd349c19e1b36c12f54923
ToppCellPND07-28-samps-Myeloid-Macrophage|PND07-28-samps / Age Group, Lineage, Cell class and subclass

PRUNE2 B3GNT7

3.66e-031622527c73fe8388af370461e04097cf145cbc9847285b
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Neural-neural_cell-Schwann_Cell_/_Neural-|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

ADGRB3 RELN

3.66e-031622525bbd7130d4dad9035e73a439dda568195c136f31
ToppCellSomatosensory_Cortex_(S1)-Neuronal-Inh_GABAergic-i_Gaba_2-GABA_PAX6-Inh_L1_PAX6_GRIP2|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

RELN BOD1L2

3.66e-03162252cc94630faa1a267b3d7699bc41477c9562e70e0a
Diseaseage at onset, multiple sclerosis

RELN BOD1L2

2.61e-0510232EFO_0004847, MONDO_0005301
DiseaseNeurobehavioral Manifestations

SELP UBE4B

3.82e-0512232C0525041
DiseaseDepression, Neurotic

SELP RELN

4.68e-0441232C0282126
DiseaseMelancholia

SELP RELN

4.68e-0441232C0025193
DiseaseDepressive Syndrome

SELP RELN

4.91e-0442232C0086133
DiseaseEndogenous depression

SELP RELN

5.89e-0446232C0011573
DiseaseOsteosarcoma

EXT2 BCOR

6.15e-0447232C0029463
Diseaseresponse to tenofovir

RELN CHAMP1

7.24e-0451232EFO_0009279
Diseaseintellectual disability (implicated_via_orthology)

NDST4 BOD1L2

1.56e-0375232DOID:1059 (implicated_via_orthology)
DiseaseAcute Confusional Senile Dementia

PCDH11X RELN

2.69e-0399232C0546126
DiseasePresenile dementia

PCDH11X RELN

2.69e-0399232C0011265
DiseaseAlzheimer's Disease, Focal Onset

PCDH11X RELN

2.69e-0399232C0750900
DiseaseAlzheimer Disease, Early Onset

PCDH11X RELN

2.69e-0399232C0750901
DiseaseAlzheimer Disease, Late Onset

PCDH11X RELN

2.69e-0399232C0494463
DiseaseFamilial Alzheimer Disease (FAD)

PCDH11X RELN

2.75e-03100232C0276496
DiseaseAlzheimer's Disease

PCDH11X RELN

2.80e-03101232C0002395
Diseasemyeloid white cell count

SELP PRUNE2 DNAJC13 SMG6

5.53e-03937234EFO_0007988
Diseaseosteoarthritis, knee

NDST4 SMG6

6.70e-03158232EFO_0004616

Protein segments in the cluster

PeptideGeneStartEntry
AGQPNWNLDEQLKQN

ARID3B

171

Q8IVW6
NKVADWLAQNNPPQM

CEP170

331

Q5SW79
WDPNNPDQKPALKTQ

SMG6

456

Q86US8
ENPAPNKNPWDTFKN

ADGRB3

1461

O60242
KQEWNPPANDNQLHD

BOD1L2

86

Q8IYS8
TDKNLKPNPNWNQGK

BCOR

781

Q6W2J9
SDLWKDGQQQPQPEK

GPANK1

16

O95872
WADQTAEQPKQNDLP

KIF18A

616

Q8NI77
NDKDKQQNSWLPANG

MMP21

531

Q8N119
EQKDPLWQNPCDDKR

NDST4

566

Q9H3R1
QKNKQNSEWATPNPE

PCDH11X

846

Q9BZA7
PEDAKGENVQFQWKQ

RELN

316

P78509
NQGENLETDQWPQKL

PTOV1

126

Q86YD1
QFPENNWINPDKLSE

DNAJA2

336

O60884
ASPDKWNDKPKNQLN

CHAMP1

86

Q96JM3
WNDKPKNQLNKETDP

CHAMP1

91

Q96JM3
KNQQDNPEANWKLPE

DNAJC13

1951

O75165
NWADNEPNNKRNNED

SELP

116

P16109
VNPNNFWKNPKDVAA

B3GNT7

56

Q8NFL0
PNPLEQDLWNQAKED

BBS1

131

Q8NFJ9
QPLENQKDQIDEQPW

LRCH2

526

Q5VUJ6
DPDKDDQNWKRPLNC

SLC8B1

346

Q6J4K2
INNEAAPEIWGKKNN

PRUNE2

856

Q8WUY3
KNKEQWDQLPRDQQQ

UBE4B

1056

O95155
NQNKNPPEDSLWPKI

EXT2

491

Q93063
EPEVPESNQKQWQSK

TTK

376

P33981