Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	ATP-dependent chromatin remodeler activity	TTF2 SMARCA5 SMARCA1 RAD54L	2.34e-06	37	51	4	GO:0140658
GeneOntologyMolecularFunction	cytoskeleton-nuclear membrane anchor activity	SYNE1 SYNE2	6.36e-05	5	51	2	GO:0140444
GeneOntologyMolecularFunction	ATP-dependent DNA/DNA annealing activity	SMARCA1 RAD54L	6.36e-05	5	51	2	GO:0036310
GeneOntologyMolecularFunction	ATP-dependent activity, acting on DNA	TTF2 SMARCA5 SMARCA1 RAD54L	3.09e-04	127	51	4	GO:0008094
GeneOntologyMolecularFunction	DNA/DNA annealing activity	SMARCA1 RAD54L	3.47e-04	11	51	2	GO:1990814
GeneOntologyMolecularFunction	annealing activity	SMARCA1 RAD54L	5.71e-04	14	51	2	GO:0140666
GeneOntologyMolecularFunction	helicase activity	TTF2 SMARCA5 SMARCA1 RAD54L	7.06e-04	158	51	4	GO:0004386
GeneOntologyMolecularFunction	ATP-dependent activity	ATP8B3 TTF2 SMARCA5 DYNC2H1 SMARCA1 KIF5C RAD54L	8.98e-04	614	51	7	GO:0140657
GeneOntologyCellularComponent	NURF complex	SMARCA5 SMARCA1	1.26e-04	7	52	2	GO:0016589
GeneOntologyCellularComponent	microtubule organizing center attachment site	SYNE1 SYNE2	3.29e-04	11	52	2	GO:0034992
GeneOntologyCellularComponent	meiotic nuclear membrane microtubule tethering complex	SYNE1 SYNE2	3.29e-04	11	52	2	GO:0034993
GeneOntologyCellularComponent	nuclear membrane protein complex	SYNE1 SYNE2	3.29e-04	11	52	2	GO:0106083
GeneOntologyCellularComponent	nuclear membrane microtubule tethering complex	SYNE1 SYNE2	3.29e-04	11	52	2	GO:0106094
GeneOntologyCellularComponent	ISWI-type complex	SMARCA5 SMARCA1	5.42e-04	14	52	2	GO:0031010
GeneOntologyCellularComponent	lamellipodium membrane	PIEZO1 SYNE2	1.36e-03	22	52	2	GO:0031258
Domain	SNF2_N	TTF2 SMARCA5 SMARCA1 RAD54L	1.68e-06	32	51	4	IPR000330
Domain	SNF2_N	TTF2 SMARCA5 SMARCA1 RAD54L	1.68e-06	32	51	4	PF00176
Domain	SLIDE	SMARCA5 SMARCA1	7.31e-06	2	51	2	IPR015195
Domain	ISWI_HAND-dom	SMARCA5 SMARCA1	7.31e-06	2	51	2	IPR015194
Domain	SLIDE	SMARCA5 SMARCA1	7.31e-06	2	51	2	PF09111
Domain	HAND	SMARCA5 SMARCA1	7.31e-06	2	51	2	PF09110
Domain	ISWI	SMARCA5 SMARCA1	7.31e-06	2	51	2	IPR029915
Domain	DBINO	SMARCA5 SMARCA1	2.19e-05	3	51	2	PF13892
Domain	DBINO	SMARCA5 SMARCA1	2.19e-05	3	51	2	IPR020838
Domain	KASH	SYNE1 SYNE2	4.37e-05	4	51	2	PF10541
Domain	KASH	SYNE1 SYNE2	4.37e-05	4	51	2	IPR012315
Domain	KASH	SYNE1 SYNE2	4.37e-05	4	51	2	PS51049
Domain	KASH	SYNE1 SYNE2	4.37e-05	4	51	2	SM01249
Domain	DEAH_ATP_HELICASE	TTF2 SMARCA5 SMARCA1	1.51e-04	38	51	3	PS00690
Domain	Helicase_C	TTF2 SMARCA5 SMARCA1 RAD54L	2.07e-04	107	51	4	PF00271
Domain	HELICc	TTF2 SMARCA5 SMARCA1 RAD54L	2.07e-04	107	51	4	SM00490
Domain	Helicase_C	TTF2 SMARCA5 SMARCA1 RAD54L	2.14e-04	108	51	4	IPR001650
Domain	HELICASE_CTER	TTF2 SMARCA5 SMARCA1 RAD54L	2.22e-04	109	51	4	PS51194
Domain	HELICASE_ATP_BIND_1	TTF2 SMARCA5 SMARCA1 RAD54L	2.22e-04	109	51	4	PS51192
Domain	DEXDc	TTF2 SMARCA5 SMARCA1 RAD54L	2.22e-04	109	51	4	SM00487
Domain	Helicase_ATP-bd	TTF2 SMARCA5 SMARCA1 RAD54L	2.30e-04	110	51	4	IPR014001
Domain	P-loop_NTPase	TTF2 SMARCA5 DYNC2H1 BMS1 SMARCA1 KIF5C NLRP2 HYDIN RAD54L	4.29e-04	848	51	9	IPR027417
Domain	-	TTF2 SMARCA5 DYNC2H1 BMS1 SMARCA1 NLRP2 HYDIN RAD54L	8.67e-04	746	51	8	3.40.50.300
Domain	Claudin_CS	CLDN24 CLDN22	1.63e-03	22	51	2	IPR017974
Domain	CLAUDIN	CLDN24 CLDN22	1.63e-03	22	51	2	PS01346
Domain	Actinin_actin-bd_CS	SYNE1 SYNE2	1.78e-03	23	51	2	IPR001589
Domain	Spectrin	SYNE1 SYNE2	1.78e-03	23	51	2	PF00435
Domain	ACTININ_2	SYNE1 SYNE2	1.78e-03	23	51	2	PS00020
Domain	ACTININ_1	SYNE1 SYNE2	1.78e-03	23	51	2	PS00019
Domain	SANT_dom	SMARCA5 SMARCA1	2.28e-03	26	51	2	IPR017884
Domain	Claudin	CLDN24 CLDN22	2.64e-03	28	51	2	IPR006187
Domain	SANT	SMARCA5 SMARCA1	2.64e-03	28	51	2	PS51293
Domain	Spectrin_repeat	SYNE1 SYNE2	2.83e-03	29	51	2	IPR002017
Domain	-	STK36 EFR3B FRYL EFR3A	3.14e-03	222	51	4	1.25.10.10
Domain	Spectrin/alpha-actinin	SYNE1 SYNE2	3.44e-03	32	51	2	IPR018159
Domain	SPEC	SYNE1 SYNE2	3.44e-03	32	51	2	SM00150
Domain	DNA/RNA_helicase_DEAH_CS	TTF2 SMARCA5	4.11e-03	35	51	2	IPR002464
Domain	PMP22_Claudin	CLDN24 CLDN22	5.34e-03	40	51	2	PF00822
Domain	ARM-like	STK36 EFR3B FRYL EFR3A	6.27e-03	270	51	4	IPR011989
Domain	PMP22/EMP/MP20/Claudin	CLDN24 CLDN22	6.71e-03	45	51	2	IPR004031
Domain	-	SMARCA5 SMARCA1 MEIS3 SSH2	7.38e-03	283	51	4	1.10.10.60
Pubmed	Multiple novel nesprin-1 and nesprin-2 variants act as versatile tissue-specific intracellular scaffolds.	SYNE1 SYNE2	2.28e-06	2	53	2	22768332
Pubmed	Nesprin-1 and -2 are involved in the pathogenesis of Emery Dreifuss muscular dystrophy and are critical for nuclear envelope integrity.	SYNE1 SYNE2	2.28e-06	2	53	2	17761684
Pubmed	Nesprin-1-alpha2 associates with kinesin at myotube outer nuclear membranes, but is restricted to neuromuscular junction nuclei in adult muscle.	SYNE1 SYNE2	2.28e-06	2	53	2	31578382
Pubmed	Nesprins: a novel family of spectrin-repeat-containing proteins that localize to the nuclear membrane in multiple tissues.	SYNE1 SYNE2	2.28e-06	2	53	2	11792814
Pubmed	Nesprin-1 and nesprin-2 regulate endothelial cell shape and migration.	SYNE1 SYNE2	2.28e-06	2	53	2	24931616
Pubmed	Antioxidant enzymes reduce DNA damage and early activation of valvular interstitial cells in aortic valve sclerosis.	CAT SOD3	2.28e-06	2	53	2	23241403
Pubmed	Syne-1 and Syne-2 play crucial roles in myonuclear anchorage and motor neuron innervation.	SYNE1 SYNE2	2.28e-06	2	53	2	17267447
Pubmed	Nesprins: tissue-specific expression of epsilon and other short isoforms.	SYNE1 SYNE2	2.28e-06	2	53	2	24718612
Pubmed	Targeted ablation of nesprin 1 and nesprin 2 from murine myocardium results in cardiomyopathy, altered nuclear morphology and inhibition of the biomechanical gene response.	SYNE1 SYNE2	2.28e-06	2	53	2	24586179
Pubmed	Binding kinetics of human ISWI chromatin-remodelers to DNA repair sites elucidate their target location mechanism.	SMARCA5 SMARCA1	6.83e-06	3	53	2	21738833
Pubmed	Distinct functional domains in nesprin-1alpha and nesprin-2beta bind directly to emerin and both interactions are disrupted in X-linked Emery-Dreifuss muscular dystrophy.	SYNE1 SYNE2	6.83e-06	3	53	2	17462627
Pubmed	Cloning and characterization of the murine Imitation Switch (ISWI) genes: differential expression patterns suggest distinct developmental roles for Snf2h and Snf2l.	SMARCA5 SMARCA1	6.83e-06	3	53	2	11359880
Pubmed	EFR3s are palmitoylated plasma membrane proteins that control responsiveness to G-protein-coupled receptors.	EFR3B EFR3A	6.83e-06	3	53	2	25380825
Pubmed	Syne-1, a dystrophin- and Klarsicht-related protein associated with synaptic nuclei at the neuromuscular junction.	SYNE1 SYNE2	6.83e-06	3	53	2	10878022
Pubmed	Oxidative response gene polymorphisms and risk of adult brain tumors.	CAT SOD3	6.83e-06	3	53	2	18682580
Pubmed	Structures of FHOD1-Nesprin1/2 complexes reveal alternate binding modes for the FH3 domain of formins.	SYNE1 SYNE2	6.83e-06	3	53	2	33472039
Pubmed	Nesprins anchor kinesin-1 motors to the nucleus to drive nuclear distribution in muscle cells.	SYNE1 SYNE2	6.83e-06	3	53	2	25516977
Pubmed	The inner nuclear membrane protein Sun1 mediates the anchorage of Nesprin-2 to the nuclear envelope.	SYNE1 SYNE2	6.83e-06	3	53	2	16079285
Pubmed	Catalase activity prevents exercise-induced up-regulation of vasoprotective proteins in venous tissue.	CAT SOD3	6.83e-06	3	53	2	21129156
Pubmed	The nesprins are giant actin-binding proteins, orthologous to Drosophila melanogaster muscle protein MSP-300.	SYNE1 SYNE2	6.83e-06	3	53	2	12408964
Pubmed	Morphine modulates HIV-1 gp160-induced murine macrophage and human monocyte apoptosis by disparate ways.	CAT SOD3	1.36e-05	4	53	2	14975589
Pubmed	Nesprin-2 interacts with meckelin and mediates ciliogenesis via remodelling of the actin cytoskeleton.	SYNE1 SYNE2	1.36e-05	4	53	2	19596800
Pubmed	SUN1 interacts with nuclear lamin A and cytoplasmic nesprins to provide a physical connection between the nuclear lamina and the cytoskeleton.	SYNE1 SYNE2	1.36e-05	4	53	2	16648470
Pubmed	Functional variants of antioxidant genes in smokers with COPD and in those with normal lung function.	CAT SOD3	1.36e-05	4	53	2	16467073
Pubmed	LINC complexes mediate the positioning of cone photoreceptor nuclei in mouse retina.	SYNE1 SYNE2	1.36e-05	4	53	2	23071752
Pubmed	Tight junction-based epithelial microenvironment and cell proliferation.	CLDN24 CLDN22	1.36e-05	4	53	2	19029935
Pubmed	Genetic polymorphisms of antioxidant enzymes in preterm infants.	CAT SOD3	1.36e-05	4	53	2	22958044
Pubmed	Outer nuclear membrane protein Kuduk modulates the LINC complex and nuclear envelope architecture.	SYNE1 SYNE2	1.36e-05	4	53	2	28716842
Pubmed	Nesprins, but not sun proteins, switch isoforms at the nuclear envelope during muscle development.	SYNE1 SYNE2	1.36e-05	4	53	2	20108321
Pubmed	Genetic polymorphisms in antioxidant enzyme genes and susceptibility to hepatocellular carcinoma in Chinese population: a case-control study.	CAT SOD3	1.36e-05	4	53	2	25894370
Pubmed	The leukodystrophy protein FAM126A (hyccin) regulates PtdIns(4)P synthesis at the plasma membrane.	EFR3B EFR3A	2.27e-05	5	53	2	26571211
Pubmed	The HARP-like domain-containing protein AH2/ZRANB3 binds to PCNA and participates in cellular response to replication stress.	SMARCA1 RAD54L	2.27e-05	5	53	2	22705370
Pubmed	Genetic polymorphisms modifying oxidative stress are associated with disease activity in rheumatoid arthritis patients.	CAT SOD3	2.27e-05	5	53	2	19242068
Pubmed	Structural requirements for the assembly of LINC complexes and their function in cellular mechanical stiffness.	SYNE1 SYNE2	2.27e-05	5	53	2	18396275
Pubmed	LINC complexes form by binding of three KASH peptides to domain interfaces of trimeric SUN proteins.	SYNE1 SYNE2	2.27e-05	5	53	2	22632968
Pubmed	Identification and functional characterization of transcriptional activators in human cells.	TTF2 MTF2 DYNC2H1 SYNE2 CAT DCAF7	3.15e-05	398	53	6	35016035
Pubmed	Structural Analysis of Different LINC Complexes Reveals Distinct Binding Modes.	SYNE1 SYNE2	3.40e-05	6	53	2	33058875
Pubmed	TorsinA binds the KASH domain of nesprins and participates in linkage between nuclear envelope and cytoskeleton.	SYNE1 SYNE2	3.40e-05	6	53	2	18827015
Pubmed	WSTF-ISWI chromatin remodeling complex targets heterochromatic replication foci.	SMARCA5 SMARCA1	3.40e-05	6	53	2	11980720
Pubmed	PtdIns4P synthesis by PI4KIIIα at the plasma membrane and its impact on plasma membrane identity.	EFR3B EFR3A	4.76e-05	7	53	2	23229899
Pubmed	[Polymorphism of the genes for antioxidant defense enzymes and their association with the development of chronic obstructive pulmonary disease in the population of Bashkortostan].	CAT SOD3	6.34e-05	8	53	2	19705749
Pubmed	USP11 Is a Negative Regulator to γH2AX Ubiquitylation by RNF8/RNF168.	USP2 RNF8	6.34e-05	8	53	2	26507658
Pubmed	Expression and regulation of antioxidant enzymes in the developing limb support a function of ROS in interdigital cell death.	CAT SOD3	6.34e-05	8	53	2	16445905
Pubmed	A PHD finger of NURF couples histone H3 lysine 4 trimethylation with chromatin remodelling.	SMARCA5 SMARCA1	8.15e-05	9	53	2	16728976
Pubmed	Nesprin 1α2 is essential for mouse postnatal viability and nuclear positioning in skeletal muscle.	SYNE1 SYNE2	1.02e-04	10	53	2	28533284
Pubmed	Nuclear membrane proteins with potential disease links found by subtractive proteomics.	SYNE1 SYNE2	1.02e-04	10	53	2	12958361
Pubmed	A conserved KASH domain protein associates with telomeres, SUN1, and dynactin during mammalian meiosis.	SYNE1 SYNE2	1.24e-04	11	53	2	22826121
Pubmed	CLDN23 gene, frequently down-regulated in intestinal-type gastric cancer, is a novel member of CLAUDIN gene family.	CLDN24 CLDN22	1.49e-04	12	53	2	12736707
Pubmed	Interactions of the Antiviral Factor Interferon Gamma-Inducible Protein 16 (IFI16) Mediate Immune Signaling and Herpes Simplex Virus-1 Immunosuppression.	SMARCA5 SYNE1 BMS1 SMARCA1 GSDMA	1.52e-04	332	53	5	25693804
Pubmed	KASH protein Syne-2/Nesprin-2 and SUN proteins SUN1/2 mediate nuclear migration during mammalian retinal development.	SYNE1 SYNE2	1.76e-04	13	53	2	21177258
Pubmed	Kelch Domain of Gigaxonin Interacts with Intermediate Filament Proteins Affected in Giant Axonal Neuropathy.	DYNC2H1 SYNE1 SYNE2 SSH2	1.93e-04	187	53	4	26460568
Pubmed	Mouse chromosomal location of four Na/H exchanger isoform genes.	PCSK1 GLS	2.05e-04	14	53	2	8824815
Pubmed	SUN1/2 and Syne/Nesprin-1/2 complexes connect centrosome to the nucleus during neurogenesis and neuronal migration in mice.	SYNE1 SYNE2	2.05e-04	14	53	2	19874786
Pubmed	Lead exposure, polymorphisms in genes related to oxidative stress, and risk of adult brain tumors.	CAT SOD3	2.36e-04	15	53	2	19505917
Pubmed	Prediction of the coding sequences of mouse homologues of KIAA gene: I. The complete nucleotide sequences of 100 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.	SYNE2 FRYL KIF5C	3.24e-04	87	53	3	12465718
Pubmed	USF1 recruits histone modification complexes and is critical for maintenance of a chromatin barrier.	SMARCA5 SMARCA1	3.43e-04	18	53	2	17846119
Pubmed	Comprehensive interactome profiling of the human Hsp70 network highlights functional differentiation of J domains.	DYNC2H1 SYNE1 PIEZO1 GLS SYNE2 BMS1 EFR3B DCAF7 EFR3A	3.77e-04	1487	53	9	33957083
Pubmed	Isoform-specific GSK3A activity is negatively correlated with human sperm motility.	SMARCA5 CAT CNTROB	3.81e-04	92	53	3	30824926
Pubmed	Chromatin remodeling enzyme Snf2h regulates embryonic lens differentiation and denucleation.	SMARCA5 SMARCA1	3.83e-04	19	53	2	27246713
Pubmed	Biology of claudins.	CLDN24 CLDN22	3.83e-04	19	53	2	18480174
Pubmed	Prediction of the coding sequences of mouse homologues of KIAA gene: II. The complete nucleotide sequences of 400 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.	SYNE1 FRMPD1 CNKSR2 SH3BP5L BAIAP3	3.87e-04	407	53	5	12693553
Pubmed	Tight junction proteins.	CLDN24 CLDN22	4.70e-04	21	53	2	12475568
Pubmed	Multifunctional strands in tight junctions.	CLDN24 CLDN22	4.70e-04	21	53	2	11283726
Pubmed	Claudin-based barrier in simple and stratified cellular sheets.	CLDN24 CLDN22	4.70e-04	21	53	2	12231346
Pubmed	Snf2h Drives Chromatin Remodeling to Prime Upper Layer Cortical Neuron Development.	SMARCA5 SMARCA1	4.70e-04	21	53	2	31680852
Pubmed	Tight junctions of the blood-brain barrier.	CLDN24 CLDN22	4.70e-04	21	53	2	10690502
Pubmed	The roles of claudin superfamily proteins in paracellular transport.	CLDN24 CLDN22	4.70e-04	21	53	2	11247307
Pubmed	CECR2 is involved in spermatogenesis and forms a complex with SNF2H in the testis.	SMARCA5 SMARCA1	4.70e-04	21	53	2	22154806
Pubmed	Prediction of the coding sequences of unidentified human genes. XII. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro.	GLS CNKSR2 FRYL	4.87e-04	100	53	3	10048485
Pubmed	Prediction of the coding sequences of unidentified human genes. XIX. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro.	SYNE1 SH3BP5L SSH2	5.16e-04	102	53	3	11214970
Pubmed	Prediction of the coding sequences of unidentified human genes. XIII. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro.	SYNE2 FRMPD1 EFR3B	5.16e-04	102	53	3	10231032
Pubmed	Prediction of the coding sequences of unidentified human genes. XV. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro.	STK36 HEG1 SYNE1	5.31e-04	103	53	3	10574462
Pubmed	Structure and function of claudins.	CLDN24 CLDN22	5.65e-04	23	53	2	18036336
Pubmed	The claudins.	CLDN24 CLDN22	5.65e-04	23	53	2	19706201
Pubmed	Snf2h-mediated chromatin organization and histone H1 dynamics govern cerebellar morphogenesis and neural maturation.	SMARCA5 SMARCA1	6.16e-04	24	53	2	24946904
Pubmed	ARHGAP24 represses β-catenin transactivation-induced invasiveness in hepatocellular carcinoma mainly by acting as a GTPase-independent scaffold.	OSBP SMARCA5 ZNF813 SMARCA1 CAT	6.17e-04	451	53	5	36168627
Pubmed	Dynamic distribution of claudin proteins in pancreatic epithelia undergoing morphogenesis or neoplastic transformation.	CLDN24 CLDN22	7.23e-04	26	53	2	22275141
Pubmed	Prediction of the coding sequences of mouse homologues of KIAA gene: IV. The complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.	STK36 DYNC2H1 GLS RNF8 SSH2	9.19e-04	493	53	5	15368895
Pubmed	Phenotypic and Interaction Profiling of the Human Phosphatases Identifies Diverse Mitotic Regulators.	SYNE2 BMS1 EFR3B FBXO33 SSH2 CNTROB EFR3A	1.02e-03	1049	53	7	27880917
Pubmed	Lem2 is essential for cardiac development by maintaining nuclear integrity.	SYNE1 SYNE2	1.10e-03	32	53	2	37067297
Pubmed	TRIP12 promotes small-molecule-induced degradation through K29/K48-branched ubiquitin chains.	SMARCA5 SMARCA1	1.17e-03	33	53	2	33567268
Pubmed	In-Depth In Vivo Crosslinking in Minutes by a Compact, Membrane-Permeable, and Alkynyl-Enrichable Crosslinker.	SMARCA5 SYNE1 GLS SYNE2 SMARCA1 CAT KIF5C SLC4A3	1.44e-03	1442	53	8	35575683
Pubmed	Discovery and Characterization of ZUFSP/ZUP1, a Distinct Deubiquitinase Class Important for Genome Stability.	USP2 VPS33A FRYL	1.48e-03	147	53	3	29576527
Cytoband	19q13.41	ZNF320 ZNF321P ZNF816	1.04e-04	78	53	3	19q13.41
Cytoband	Ensembl 112 genes in cytogenetic band chr2q35	MREG STK36 SLC4A3	4.58e-04	129	53	3	chr2q35
Cytoband	4q35.1	CLDN24 CLDN22	8.03e-04	36	53	2	4q35.1
Cytoband	Ensembl 112 genes in cytogenetic band chr19q13	ZNF320 ZNF321P ZNF813 ZNF816 MEIS3 NLRP2	2.45e-03	1192	53	6	chr19q13
Cytoband	2q35	MREG STK36	3.81e-03	79	53	2	2q35
GeneFamily	Spectrin repeat containing nuclear envelope family	SYNE1 SYNE2	1.93e-05	4	33	2	1252
GeneFamily	Claudins	CLDN24 CLDN22	7.98e-04	23	33	2	488
GeneFamily	GATA zinc finger domain containing\|Myb/SANT domain containing	SMARCA5 SMARCA1	4.20e-03	53	33	2	532
ToppCell	facs-Large_Intestine-Proximal-3m-Epithelial-enteroendocrine_cell\|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MREG SMARCA1 GSDMA CNKSR2 BAIAP3 JHY	6.93e-08	178	53	6	30ca37f70d267cc9b40ca3e211f16d30360c3e6b
ToppCell	3'-GW_trimst-2-SmallIntestine-Epithelial-neuro-epithelial-M/X_cells_(MLN/GHRL+)\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	PCSK1 KCNH7 QPCT VSIG8 KIF5C	1.60e-06	166	53	5	f0912ce0df5ede3bc5e7c99ccfe4decc16c6064e
ToppCell	5'-GW_trimst-2-LargeIntestine-Epithelial-neuro-epithelial-L_cells_(PYY+)\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	PCSK1 KCNH7 QPCT KIF5C BAIAP3	1.80e-06	170	53	5	6a98f47f8c2b5b15e09169bd82eff1e6bf76e5a6
ToppCell	5'-GW_trimst-2-SmallIntestine-Epithelial-neuro-epithelial-M/X_cells_(MLN/GHRL+)\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	PCSK1 KCNH7 QPCT KIF5C BAIAP3	2.45e-06	181	53	5	cb17c904ab86d56dd30cac9b61acbb3b76f84ded
ToppCell	PND10-Epithelial-Epithelial_Airway-Neurosecretory-PNEC\|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	PCSK1 KCNH7 KIF5C SLC4A3 JHY	2.51e-06	182	53	5	1923932a9c60e9ec33db69ded441210d1fb07bec
ToppCell	PND10-Epithelial-Epithelial_Airway-Neurosecretory-PNEC-PNEC_mature\|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	PCSK1 KCNH7 KIF5C SLC4A3 JHY	2.51e-06	182	53	5	69ff652f74cc47fbe0bd665ab17c445c5b959dad
ToppCell	wk_15-18-Epithelial-Proximal_epithelial-GHRL+_neuroendocrine\|wk_15-18 / Celltypes from embryonic and fetal-stage human lung	PCSK1 KCNH7 FRMPD1 QPCT KIF5C	2.58e-06	183	53	5	8820cfed27b292bc0bc9cde4005219ed41900552
ToppCell	facs-Large_Intestine-Distal-3m-Epithelial-enteroendocrine_cell\|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MREG SMARCA1 QPCT KIF5C BAIAP3	2.65e-06	184	53	5	3da93e7d8b62463e307cc0425c47dbd3bef66799
ToppCell	facs-Large_Intestine-Proximal-24m-Epithelial-enteroendocrine_cell\|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PCSK1 MREG GSDMA BAIAP3 JHY	2.72e-06	185	53	5	2a8104f610fa5ce618f8105521616722462a0d42
ToppCell	PCW_10-12-Epithelial-Epithelial_neuroendo-epi_neuroendocrine1[NE1]_(11)\|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung	PCSK1 KCNH7 QPCT KIF5C BAIAP3	2.87e-06	187	53	5	98477ba04a42a8da80a72f41a182429f46283595
ToppCell	PCW_10-12-Epithelial-Epithelial_neuroendo\|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung	PCSK1 KCNH7 QPCT KIF5C BAIAP3	3.10e-06	190	53	5	2375e604eacd38f61f3e661ba2f76d286fcceca7
ToppCell	PCW_07-8.5-Epithelial-Epithelial_neuroendo-epi_neuroendocrine1[NE1]_(11)\|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung	PCSK1 KCNH7 QPCT KIF5C BAIAP3	3.10e-06	190	53	5	b1095b2a7467c152d16e4f19a9515aeb61fc9e3d
ToppCell	wk_08-11-Epithelial-Proximal_epithelial-GHRL+_neuroendocrine\|wk_08-11 / Celltypes from embryonic and fetal-stage human lung	PCSK1 KCNH7 FRMPD1 QPCT BAIAP3	3.10e-06	190	53	5	b5c6f3248c0c2f648e1578457c6a729ca22bf0da
ToppCell	renal_medulla_nuclei-CKD+DKD_normotensive-Epithelial-Intermediate_tubule_epithelial_cell\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	SYNE1 SYNE2 CLDN22 SSH2 HYDIN	3.43e-06	194	53	5	e577d9e88390b36b5a09b97fe1026089892275a3
ToppCell	10x5'-GI_large-bowel-Lymphocytic_T_CD4-Teffector/EM_CD4\|GI_large-bowel / Manually curated celltypes from each tissue	ZNF320 PIEZO1 CLDN22 CNKSR2	3.57e-05	156	53	4	01f2c0c6a936dfb59bc727feef428a906ad2a80b
ToppCell	Bronchial-10x5prime-Stromal-Myofibroblastic-Muscle_smooth_airway_ASM\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	USP2 PRELID2 BAIAP3 SOD3	3.84e-05	159	53	4	7cda111bb98f1241989e49d490bdf51a712ea589
ToppCell	5'-GW_trimst-2-LargeIntestine-Epithelial-neuro-epithelial-EECs\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	PCSK1 ZNF813 KIF5C BAIAP3	4.44e-05	165	53	4	4b4e75ad0eb0a6b00c30a000ec6267e23ba2e496
ToppCell	5'-GW_trimst-2-SmallIntestine-Epithelial-neuro-epithelial-K_cells_(GIP+)\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	PCSK1 KCNH7 QPCT BAIAP3	4.55e-05	166	53	4	afba41e15478053f11815acf568d29187de75492
ToppCell	PBMC_fresh-frozen-Severe-critical_progression_d12-22_no-steroids-Lymphocytic-Lymphocytic_ILC\|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)	HEG1 SYNE1 SYNE2 VPS33A	5.22e-05	172	53	4	86f52f486d67217fc1b8443ab362c975df2974a4
ToppCell	PBMC_fresh-frozen-Severe-critical_progression_d12-22_no-steroids-Lymphocytic-Lymphocytic_ILC-NK_cell-NK_c01-FCGR3A\|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)	HEG1 SYNE1 SYNE2 VPS33A	5.22e-05	172	53	4	fb2df8fea6df5947165f13978f1d1006d15b60fd
ToppCell	PBMC_fresh-frozen-Severe-critical_progression_d12-22_no-steroids-Lymphocytic-Lymphocytic_ILC-NK_cell\|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)	HEG1 SYNE1 SYNE2 VPS33A	5.22e-05	172	53	4	e38ebb216e4ddcd008148fcbaf709b4f3c83706a
ToppCell	3'-GW_trimst-1-SmallIntestine-Epithelial-neuro-epithelial-D_cells_(SST+)\|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	PCSK1 QPCT KIF5C BAIAP3	5.46e-05	174	53	4	019eae059bd9eb107dee8f0d0f574ca36c2c26e1
ToppCell	PCW_05-06-Epithelial-Epithelial_neuroendo-epi_neuroendocrine1[NE1]_(11)\|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung	PCSK1 QPCT KIF5C BAIAP3	5.58e-05	175	53	4	9941c35601134d88d1b3249c81f8b43a8fc61610
ToppCell	5'-Adult-SmallIntestine-Hematopoietic-T_cells-SELL+_CD4_T\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	ATP8B3 ZNF813 CNKSR2 JHY	5.71e-05	176	53	4	ac83a6cd4bcbb9ca1fc02a9fbd9d9629ef1df8ca
ToppCell	facs-Large_Intestine-Proximal-18m-Epithelial-enteroendocrine_cell\|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PCSK1 MREG QPCT BAIAP3	6.23e-05	180	53	4	9db9899ca42455310e9b63df523fe6c4780abfb7
ToppCell	3'-GW_trimst-2-LargeIntestine-Epithelial-neuro-epithelial-EC_cells_(TAC1+)\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	PCSK1 QPCT KIF5C BAIAP3	6.23e-05	180	53	4	d553aba594f5304f1c09ff9c6d49b64cd7ee7850
ToppCell	5'-GW_trimst-2-LargeIntestine-Epithelial-neuro-epithelial-EC_cells_(NPW+)\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	PCSK1 QPCT KIF5C BAIAP3	6.36e-05	181	53	4	2392af8c7f040c23a7d416c2e37419954970c8f4
ToppCell	5'-GW_trimst-2-LargeIntestine-Epithelial-neuro-epithelial\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	PCSK1 QPCT KIF5C BAIAP3	6.50e-05	182	53	4	0e589bf97d51b4b2f723f8c45853ad81b7ce8778
ToppCell	facs-Large_Intestine-Distal-24m-Epithelial-enteroendocrine_cell\|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MREG QPCT KIF5C BAIAP3	6.50e-05	182	53	4	398ce074a04f6482470b488f1affae4af7d2ec58
ToppCell	facs-Large_Intestine-Distal-18m-Epithelial-enteroendocrine_cell\|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MREG QPCT KIF5C BAIAP3	6.64e-05	183	53	4	d26c7b79895de28961b8d68351f28d4bb531c75c
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell-Descending_Thin_Limb_Cell_Type_1\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	SYNE1 CLDN22 HYDIN SOD3	6.64e-05	183	53	4	cfae90c309622b5d499e62a3a8a8b9746478d28d
ToppCell	CV-Healthy-7\|CV / Virus stimulation, Condition and Cluster	OSBP QPCT CNTROB JHY	6.78e-05	184	53	4	0e5cc77aaa73ceb791f8be7456177577fd2e5586
ToppCell	CV-Healthy-7\|Healthy / Virus stimulation, Condition and Cluster	OSBP GLS QPCT JHY	6.92e-05	185	53	4	1979d189c204f4c2893e3170a514ee7d5523406c
ToppCell	facs-Brain_Non-Myeloid-Striatum-24m-Mesenchymal-brain_pericyte\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SYNE2 MEIS3 SLC4A3 SOD3	6.92e-05	185	53	4	38486b69c48dc5e1c4e1488208fa8954a973eccb
ToppCell	NS-moderate-d_16-33-Epithelial-Ciliated\|d_16-33 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	USP2 DYNC2H1 BAIAP3 HYDIN	6.92e-05	185	53	4	5e689c2fb36ce3ac2adc8d15f67107f21cf68868
ToppCell	facs-Brain_Non-Myeloid-Striatum-24m-Mesenchymal-Pericyte\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SYNE2 MEIS3 SLC4A3 SOD3	6.92e-05	185	53	4	3c28b5ceba3cfdb6f7e32d5b42e03b6a81a7a658
ToppCell	5'-Adult-Distal_Rectal-Mesenchymal-fibroblastic-Stromal_1_(CCL11+)\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	CLDN22 MEIS3 HYDIN SOD3	7.07e-05	186	53	4	f07e0c0d9c80ac9d8d679950e7d0c812becb85a3
ToppCell	droplet-Marrow-nan-3m-Hematologic-megakaryocyte-erythroid_progenitor_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MREG SMARCA5 SYNE1 SYNE2	7.22e-05	187	53	4	14c239af77116d28d511dea754b6150d20488080
ToppCell	3'-Broncho-tracheal-Epithelial-Neuro-endocrine/ionocytic-lung_neuroendocrine_cell-Neuroendocrine\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	PCSK1 KCNH7 QPCT KIF5C	7.68e-05	190	53	4	40d8b3403f4e38436b961cd3a2e69826cbae3042
ToppCell	3'-Broncho-tracheal-Epithelial-Neuro-endocrine/ionocytic-lung_neuroendocrine_cell-Neuroendocrine-Neuroendocrine_L.0.7.2.0\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	PCSK1 KCNH7 QPCT KIF5C	7.68e-05	190	53	4	f6cbf6d292f488ada5f7581e1dceba6198b933d1
ToppCell	wk_08-11-Epithelial-Proximal_epithelial-intermediate_neuroendocrine\|wk_08-11 / Celltypes from embryonic and fetal-stage human lung	PCSK1 QPCT KIF5C BAIAP3	7.68e-05	190	53	4	5f1863bce9400b7c932f0e4d0e012ec4e8d7e555
ToppCell	3'-Broncho-tracheal-Epithelial-Neuro-endocrine/ionocytic-lung_neuroendocrine_cell\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	PCSK1 KCNH7 QPCT KIF5C	7.68e-05	190	53	4	a9a705455019e28d655636de73b07540798f82e6
ToppCell	wk_08-11-Epithelial-Proximal_epithelial-GHRL+_NE_precursor\|wk_08-11 / Celltypes from embryonic and fetal-stage human lung	PCSK1 QPCT KIF5C BAIAP3	7.83e-05	191	53	4	f0a81f621e63e87ff62224b33cf0c71dfac1d6e2
ToppCell	Ciliated-cil-3\|World / Class top	STK36 DYNC2H1 SYNE1 HYDIN	7.99e-05	192	53	4	4989ebb8812b8af1870599acd932849122c05a29
ToppCell	5'-GW_trimst-2-SmallIntestine-Epithelial-neuro-epithelial\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	PCSK1 KCNH7 QPCT BAIAP3	7.99e-05	192	53	4	5692bd57093852d442400383850f416c497dcc7d
ToppCell	TCGA-Prostate-Primary_Tumor-Prostate_Adenocarcinoma-Acinar_Adenocarcinoma-6\|TCGA-Prostate / Sample_Type by Project: Shred V9	SMARCA5 FRYL DCAF7 EFR3A	8.15e-05	193	53	4	abd71b2cf667ef2b1c4d88acd0c1dd19a12ff659
ToppCell	renal_medulla_nuclei-CKD+DKD_normotensive-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Thick_Ascending_Limb_Cell\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	SYNE1 SYNE2 CLDN22 SSH2	8.15e-05	193	53	4	f42a0f02ed00fe1bb833ff0a0640d9131bca89bd
ToppCell	renal_medulla_nuclei-CKD+DKD_normotensive-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	SYNE1 SYNE2 CLDN22 SSH2	8.15e-05	193	53	4	42df7ed37d11fb542b4d1d714b6f87ae8e1396a6
ToppCell	PCW_07-8.5-Epithelial-Epithelial_neuroendo\|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung	PCSK1 KCNH7 KIF5C BAIAP3	8.32e-05	194	53	4	b30379f8dc41c86c746af9930541fbb4819d8fa0
ToppCell	IPF-Multiplet-Multiplet\|IPF / Disease state, Lineage and Cell class	DYNC2H1 SYNE1 SYNE2 HYDIN	8.49e-05	195	53	4	fce0c29574bb7aab181b9c00feb42681e285d1f2
ToppCell	IPF-Multiplet\|IPF / Disease state, Lineage and Cell class	DYNC2H1 SYNE1 SYNE2 HYDIN	8.49e-05	195	53	4	eacc0449ae6f3ad8002268cd061467684c6fb9a7
ToppCell	PCW_13-14-Epithelial-Epithelial_neuroendo-epi_neuroendocrine1[NE1]_(11)\|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung	PCSK1 KCNH7 QPCT KIF5C	8.49e-05	195	53	4	5f33ece997f074598b4201ff74f592ee07c86a06
ToppCell	moderate-Epithelial-Ciliated\|Epithelial / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls	DYNC2H1 SYNE1 BAIAP3 HYDIN	8.49e-05	195	53	4	3486eae5fdb062a75a907b896c9d7b396d2aa195
ToppCell	moderate-Epithelial-Ciliated\|moderate / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls	USP2 DYNC2H1 BAIAP3 HYDIN	8.49e-05	195	53	4	e80f5cdf0b18066b3e6c2f5452e58f101c67932c
ToppCell	Mid-temporal_gyrus_(MTG)-Neuronal\|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	SYNE1 GLS CNKSR2 KIF5C	8.65e-05	196	53	4	676c56b44ac29f7baecb62f49bb8597cc74c0a88
ToppCell	Epithelial_cells-AT1_cells\|Epithelial_cells / lung cells shred on cell class, cell subclass, sample id	HEG1 PIEZO1 EFR3B CNKSR2	8.65e-05	196	53	4	6c99d29162848161c1f166a032320f87a5d5a631
ToppCell	3'-Parenchyma_lung-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.2.2\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	DYNC2H1 SYNE1 SYNE2 HYDIN	8.83e-05	197	53	4	74a2c6cb8fcfe53dd9a2b36492a16c58f38e51c9
ToppCell	Transverse-Dendritic_cell-Lymphoid_DC\|Dendritic_cell / Region, Cell class and subclass	ATP8B3 HEG1 VSIG8 BAIAP3	8.83e-05	197	53	4	8545baf923ddf84c5ce9414a36d810603be52401
ToppCell	Somatosensory_Cortex_(S1)-Neuronal\|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	SYNE1 GLS CNKSR2 KIF5C	9.00e-05	198	53	4	c01091ef18e096d792ea2a7a715764a5b215355f
ToppCell	primary_auditory_cortex_(A1C)-Neuronal\|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	SYNE1 GLS CNKSR2 KIF5C	9.00e-05	198	53	4	6d18b45eda4014759e6dd282d78ffd28df8a6044
ToppCell	Primary_Visual_cortex_(V1C)-Neuronal\|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	SYNE1 GLS CNKSR2 KIF5C	9.00e-05	198	53	4	8ab40fae14fe02e39bc8c8da187a5cd60c787643
ToppCell	mild-MAIT\|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class	SYNE1 GLS SYNE2 KIF5C	9.18e-05	199	53	4	cbe1fb6d2c5fca7a1baf1ad20afcdf8e8e11bd84
ToppCell	mild-low-quality_cells\|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class	SYNE1 GLS SYNE2 FRYL	9.18e-05	199	53	4	f0b0097df0026496470a80d8cc9375ffd8389b00
ToppCell	(7)_Epithelial_cells-(7)_Epithelial-I_(AT1)\|(7)_Epithelial_cells / Lung cell shreds - cell class (v4) and cell subclass (v4)	HEG1 PIEZO1 EFR3B CNKSR2	9.18e-05	199	53	4	5a002d49a8b84c158f7b4d7a3e78e6a937757bb7
ToppCell	Neuronal\|World / cells hierarchy compared to all cells using T-Statistic	SYNE1 GLS CNKSR2 KIF5C	9.36e-05	200	53	4	48d801219bc771d6c7e151dc88ca4c179988de85
ToppCell	(09)_Interm._secr.>cil.\|World / shred by cell type by condition	DYNC2H1 SYNE1 BAIAP3 HYDIN	9.36e-05	200	53	4	3305e14dba12e94da42f0414fdc7a2c8caf0a183
Disease	Autosomal dominant Emery-Dreifuss muscular dystrophy	SYNE1 SYNE2	1.68e-05	4	50	2	cv:CN293514
Disease	Autosomal Recessive Emery-Dreifuss Muscular Dystrophy	SYNE1 SYNE2	2.80e-05	5	50	2	C1450051
Disease	Autosomal Dominant Emery-Dreifuss Muscular Dystrophy (disorder)	SYNE1 SYNE2	2.80e-05	5	50	2	C0410190
Disease	Emery-Dreifuss muscular dystrophy	SYNE1 SYNE2	4.20e-05	6	50	2	cv:C0410189
Disease	Muscular Dystrophy, Emery-Dreifuss	SYNE1 SYNE2	4.20e-05	6	50	2	C0410189
Disease	X-Linked Emery-Dreifuss Muscular Dystrophy	SYNE1 SYNE2	5.88e-05	7	50	2	C0751337
Disease	Emery-Dreifuss muscular dystrophy (implicated_via_orthology)	SYNE1 SYNE2	1.84e-04	12	50	2	DOID:11726 (implicated_via_orthology)
Disease	central nervous system disease (implicated_via_orthology)	SMARCA5 SMARCA1	3.33e-04	16	50	2	DOID:331 (implicated_via_orthology)
Disease	hydrocephalus (implicated_via_orthology)	STK36 HYDIN	4.72e-04	19	50	2	DOID:10908 (implicated_via_orthology)
Disease	hyperthyroidism (biomarker_via_orthology)	PCSK1 CAT	1.03e-03	28	50	2	DOID:7998 (biomarker_via_orthology)
Disease	Kartagener Syndrome	STK36 HYDIN	1.62e-03	35	50	2	C0022521
Disease	Polynesian Bronchiectasis	STK36 HYDIN	1.62e-03	35	50	2	C4317124
Disease	Ciliary Dyskinesia, Primary, 1, With Or Without Situs Inversus	STK36 HYDIN	1.62e-03	35	50	2	C4551906

Protein segments in the cluster

Peptide	Gene	Start	Entry
NELMLDRSQEPHWRE	SLC4A3	326	P48751
PHWKNLNLDLNEMEN	CLDN24	31	A6NM45
DPASDQMQHWKEQRA	CAT	6	P04040
DKNRLDPTWQEMLNH	SH3BP5L	161	Q7L8J4
EDMQAHWEEAPSLPQ	BAIAP3	481	O94812
DEWDIPHICNDNMQT	GSDMA	216	Q96QA5
EPRALAQNVNMDEAW	ATP8B3	836	O60423
APHDWDLEEVMNSIR	BMS1	741	Q14692
HAMEQRPSQELLWEL	CARD9	236	Q9H257
ADDHQALIWDIQQMP	DCAF7	286	P61962
NDELRATIWEPQHMD	EFR3A	181	Q14156
ELMTYINENWDRLHP	MTF2	291	Q9Y483
PEVWHTMDDNEENLD	QPCT	326	Q16769
NPANDEQAMARVWRD	RAD54L	596	Q92698
KDRWNNTPMDEALHF	GLS	616	O94925
EMENAAIDPEDKWHQ	JHY	306	Q6NUN7
DMRSWERENAHPQPE	KCNH7	991	Q9NS40
LDNMPNDEHWKALSR	FBXO33	351	Q7Z6M2
MQDPNADTEWNDILR	PDCL3	1	Q9H2J4
DELQANIWDPQHMDK	EFR3B	181	Q9Y2G0
DDEEEAWRCHVNQML	FRYL	2681	O94915
LPDQNNMWIRDHEDS	MEIS3	196	Q99687
ERSQDDQHMLPFWTD	NLRP2	676	Q9NX02
NPRSQEWGREAIEMH	HEG1	1301	Q9ULI3
QRLMENGRWDEANAE	OSBP	721	P22059
PHWKNLNLDLNEMEN	CLDN22	31	Q8N7P3
VRGMHPELFQENEWD	DYNC2H1	3576	Q8NCM8
QLPADQVPDWDDRMH	HYDIN	3736	Q4G0P3
LQMNNEPAEDLSWER	FRMPD1	101	Q5SYB0
ERLQAMLQAHWDEAN	CNTROB	551	Q8N137
EDIQGDDRWMSQHNR	PAFAH1B2	16	P68402
WNPQVDLQAMDRAHR	SMARCA1	596	P28370
AQALQEHWALMEELN	RNF8	341	O76064
LMEWAEEQQPNIAEA	SYNE1	4356	Q8NF91
AFDRWEMIQAQELHN	SYNE2	6531	Q8WXH0
QHLEMELNRWRNGEA	KIF5C	361	O60282
RDDEKNLWSMPHDVS	MREG	46	Q8N565
NEEPDSDNEWQHLLE	STK36	411	Q9NRP7
AEHLDDMNRWLNRIN	CNKSR2	651	Q8WXI2
FQWQEEERNGHEAPM	ZNF321P	46	Q8N8H1
EWMQVNSDPAHHREN	VSIG8	61	P0DPA2
WQEDETNDHEAPMTE	ZNF320	101	A2RRD8
NEWNAMQDVQSHRPD	SSH2	221	Q76I76
WQEVMQRRDDDGALH	SOD3	46	P08294
QLEEESWLNPRERNM	PRELID2	91	Q8N945
WQEDERNSHEAPMTE	ZNF813	101	Q6ZN06
AELDQWPQERESDQH	PIEZO1	356	Q92508
RLWMDDVNEQNPTDI	VPS33A	471	Q96AX1
WNPQVDLQAMDRAHR	SMARCA5	581	O60264
NLDHLPDDEKGRQMW	USP2	386	O75604
QWQEVERNGHEAPMT	ZNF816	116	Q0VGE8
LDMHWNPSLEDQACD	TTF2	1086	Q9UNY4
LEANPNLTWRDMQHL	PCSK1	396	P29120