Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	phosphatidylserine flippase activity	ATP8A2 ATP11C ATP11A	1.44e-05	5	228	3	GO:0140346
GeneOntologyMolecularFunction	minus-end-directed microtubule motor activity	DNAH9 DNAH3 DNAH12 DNAH17	4.47e-05	18	228	4	GO:0008569
GeneOntologyMolecularFunction	aminophospholipid flippase activity	ATP8A2 ATP11C ATP11A	4.97e-05	7	228	3	GO:0015247
GeneOntologyMolecularFunction	phosphatidylethanolamine flippase activity	ATP8A2 ATP11C ATP11A	4.97e-05	7	228	3	GO:0090555
GeneOntologyMolecularFunction	ATP hydrolysis activity	KIF1A ABCA13 ATP8A2 KIF1B ABCA8 ATP11C ATP11A ATP13A3 DNAH9 DNAH3 ABCB6 CHD8 HELQ DNAH12 ATAD1 HSP90AB2P	5.06e-05	441	228	16	GO:0016887
GeneOntologyMolecularFunction	dynein intermediate chain binding	DNAH9 DNAH3 DNAH12 DNAH17 HTT	6.01e-05	37	228	5	GO:0045505
GeneOntologyMolecularFunction	ATP-dependent activity	KIF1A MYO7A ABCA13 ATP8A2 KIF1B ABCA8 ACSF3 ATP11C ATP11A ATP13A3 DNAH9 DNAH3 ABCB6 CHD8 HELQ DNAH12 ATAD1 DNAH17 HSP90AB2P	8.59e-05	614	228	19	GO:0140657
GeneOntologyMolecularFunction	phosphatidylserine floppase activity	ATP8A2 ATP11C ATP11A	1.17e-04	9	228	3	GO:0090556
GeneOntologyMolecularFunction	microtubule motor activity	KIF1A KIF1B DNAH9 DNAH3 DNAH12 DNAH17	1.48e-04	70	228	6	GO:0003777
GeneOntologyMolecularFunction	dynein light intermediate chain binding	DNAH9 DNAH3 DNAH12 DNAH17	2.73e-04	28	228	4	GO:0051959
GeneOntologyMolecularFunction	intramembrane lipid transporter activity	ATP8A2 ANO5 ATP11C ATP11A ANO8	2.85e-04	51	228	5	GO:0140303
GeneOntologyMolecularFunction	cytoskeletal motor activity	KIF1A MYO7A KIF1B DNAH9 DNAH3 DNAH12 DNAH17	4.16e-04	118	228	7	GO:0003774
GeneOntologyMolecularFunction	lipid transporter activity	ABCA13 ATP8A2 ANO5 ABCA8 ATP11C ATP11A ATG2B APOB ANO8	4.35e-04	196	228	9	GO:0005319
GeneOntologyMolecularFunction	glycerophospholipid flippase activity	ATP8A2 ATP11C ATP11A	4.87e-04	14	228	3	GO:0140333
GeneOntologyMolecularFunction	phosphotransferase activity, alcohol group as acceptor	SMG1 NT5C3A ITK RPS6KC1 TAOK3 PIK3CA UCKL1 SYK MAP3K9 PRKD2 NPR2 KSR2 TGFBR2 NRBP2 IGF2R TBK1 NT5C2 SRPK3 MAPK4	5.27e-04	709	228	19	GO:0016773
GeneOntologyMolecularFunction	floppase activity	ATP8A2 ATP11C ATP11A	7.37e-04	16	228	3	GO:0140328
GeneOntologyMolecularFunction	putrescine transmembrane transporter activity	ATP13A3 SLC47A1	7.67e-04	4	228	2	GO:0015489
GeneOntologyMolecularFunction	flippase activity	ATP8A2 ATP11C ATP11A	8.88e-04	17	228	3	GO:0140327
GeneOntologyMolecularFunction	nucleotidase activity	NT5C3A BPNT2 NT5C2	1.06e-03	18	228	3	GO:0008252
GeneOntologyMolecularFunction	histone H3K9me/H3K9me2 demethylase activity	KDM3A KDM3B	1.27e-03	5	228	2	GO:0140683
GeneOntologyBiologicalProcess	aminophospholipid transport	ATP8A2 ATP11C ATP11A SCARB2	1.72e-06	9	227	4	GO:0015917
GeneOntologyBiologicalProcess	intracellular transport	SMG1 AHCYL1 INTU KIF1A MYO7A VPS13C KIF1B GCKR ACTN2 KCNIP3 NF1 CEP120 CLN5 VPS13A NXF3 SYK KCNQ2 DENND5A HERC2 RGPD5 RPH3AL RGPD8 FERMT1 CPT1B NCOA4 DENND1A WDR91 IGF2R CSE1L IGHG3 IGHG4 SCARB2 RIMS1 LRBA BBS12 SIX2 HTT	2.86e-06	1496	227	37	GO:0046907
GeneOntologyCellularComponent	lysosome	MYO7A ARSK ABCA13 VPS13C RPS6KC1 CLN5 VPS13A ATP11C ATP11A NOS1 CAP1 WDR48 ABCB6 CP APOB NCOA4 USP6 SCARB2 NPRL3 LRRC8A LRBA CTSH	8.97e-05	811	229	22	GO:0005764
GeneOntologyCellularComponent	lytic vacuole	MYO7A ARSK ABCA13 VPS13C RPS6KC1 CLN5 VPS13A ATP11C ATP11A NOS1 CAP1 WDR48 ABCB6 CP APOB NCOA4 USP6 SCARB2 NPRL3 LRRC8A LRBA CTSH	8.97e-05	811	229	22	GO:0000323
GeneOntologyCellularComponent	axonemal dynein complex	DNAH9 DNAH3 DNAH12 DNAH17	1.48e-04	25	229	4	GO:0005858
GeneOntologyCellularComponent	vacuole	MYO7A ARSK ABCA13 VPS13C RPS6KC1 CLN5 VPS13A ATP11C ATP11A NOS1 CAP1 WDR48 ABCB6 CP APOB NCOA4 USP6 SCARB2 NPRL3 LRRC8A LRBA CTSH HTT	1.84e-04	913	229	23	GO:0005773
GeneOntologyCellularComponent	phospholipid-translocating ATPase complex	ATP8A2 ATP11C ATP11A	4.32e-04	14	229	3	GO:1990531
Domain	PH_dom-like	KIF1A MYO7A KIF1B ITK PLCG2 PLEKHH2 FERMT2 NSMAF FERMT3 RGPD5 PRKD2 RGPD8 RASA1 FERMT1 NBEA PLEKHG2 WDFY4 LRBA PHLPP2	9.29e-07	426	223	19	IPR011993
Domain	PH_BEACH	NSMAF NBEA WDFY4 LRBA	1.33e-06	8	223	4	PS51783
Domain	PH-BEACH_dom	NSMAF NBEA WDFY4 LRBA	1.33e-06	8	223	4	IPR023362
Domain	-	NSMAF NBEA WDFY4 LRBA	1.33e-06	8	223	4	2.30.29.40
Domain	BEACH	NSMAF NBEA WDFY4 LRBA	2.38e-06	9	223	4	PS50197
Domain	Beach	NSMAF NBEA WDFY4 LRBA	2.38e-06	9	223	4	SM01026
Domain	BEACH_dom	NSMAF NBEA WDFY4 LRBA	2.38e-06	9	223	4	IPR000409
Domain	Beach	NSMAF NBEA WDFY4 LRBA	2.38e-06	9	223	4	PF02138
Domain	-	NSMAF NBEA WDFY4 LRBA	2.38e-06	9	223	4	1.10.1540.10
Domain	-	ATP8A2 NT5C3A ATP11C ATP11A ATP13A3 LPIN2 NT5C2	1.10e-05	64	223	7	3.40.50.1000
Domain	Autophagy-rel_C	VPS13C VPS13A ATG2B	1.65e-05	5	223	3	IPR015412
Domain	ATG_C	VPS13C VPS13A ATG2B	1.65e-05	5	223	3	PF09333
Domain	HAD-like_dom	ATP8A2 NT5C3A ATP11C ATP11A ATP13A3 LPIN2 NT5C2	4.40e-05	79	223	7	IPR023214
Domain	Chorein_N	VPS13C VPS13A ATG2B	9.00e-05	8	223	3	PF12624
Domain	VPS13_N	VPS13C VPS13A ATG2B	9.00e-05	8	223	3	IPR026854
Domain	PH	KIF1A KIF1B ITK PLCG2 PLEKHH2 FERMT2 FERMT3 PRKD2 RASA1 FERMT1 PLEKHG2	1.01e-04	229	223	11	PF00169
Domain	PH_DOMAIN	KIF1A KIF1B ITK PLCG2 PLEKHH2 FERMT2 FERMT3 PRKD2 RASA1 FERMT1 PLEKHG2 PHLPP2	1.40e-04	279	223	12	PS50003
Domain	Thr_synth_N	THNSL1 THNSL2	1.42e-04	2	223	2	PF14821
Domain	K_chnl_volt-dep_KCNQ2	KCNQ5 KCNQ2	1.42e-04	2	223	2	IPR003947
Domain	-	THNSL1 THNSL2	1.42e-04	2	223	2	3.90.1380.10
Domain	XAP5	FAM50B FAM50A	1.42e-04	2	223	2	IPR007005
Domain	Thr_synthase-like	THNSL1 THNSL2	1.42e-04	2	223	2	IPR004450
Domain	DUF1088	NBEA LRBA	1.42e-04	2	223	2	PF06469
Domain	Thr_synth_N	THNSL1 THNSL2	1.42e-04	2	223	2	IPR029144
Domain	DUF1088	NBEA LRBA	1.42e-04	2	223	2	IPR010508
Domain	XAP5	FAM50B FAM50A	1.42e-04	2	223	2	PF04921
Domain	FERM_M	MYO7A PLEKHH2 FERMT2 FERMT3 FERMT1	2.13e-04	46	223	5	PF00373
Domain	-	KIF1A MYO7A KIF1B ITK PLCG2 PLEKHH2 FERMT2 FERMT3 PRKD2 RGPD8 RASA1 FERMT1 PLEKHG2 PHLPP2	2.68e-04	391	223	14	2.30.29.30
Domain	-	MYO7A PLEKHH2 FERMT2 FERMT3 FERMT1	2.88e-04	49	223	5	1.20.80.10
Domain	FERM_central	MYO7A PLEKHH2 FERMT2 FERMT3 FERMT1	2.88e-04	49	223	5	IPR019748
Domain	ConA-like_dom	LAMA1 TRIM34 TRIM77 TRIM6 SEL1L3 NBEA TRIM5 TRIM9 CNTNAP2 LRBA	3.12e-04	219	223	10	IPR013320
Domain	FERM/acyl-CoA-bd_prot_3-hlx	MYO7A PLEKHH2 FERMT2 FERMT3 FERMT1	3.17e-04	50	223	5	IPR014352
Domain	FERM_1	MYO7A PLEKHH2 FERMT2 FERMT3 FERMT1	3.17e-04	50	223	5	PS00660
Domain	FERM_2	MYO7A PLEKHH2 FERMT2 FERMT3 FERMT1	3.17e-04	50	223	5	PS00661
Domain	FERM_3	MYO7A PLEKHH2 FERMT2 FERMT3 FERMT1	3.17e-04	50	223	5	PS50057
Domain	Band_41_domain	MYO7A PLEKHH2 FERMT2 FERMT3 FERMT1	3.17e-04	50	223	5	IPR019749
Domain	B41	MYO7A PLEKHH2 FERMT2 FERMT3 FERMT1	3.17e-04	50	223	5	SM00295
Domain	VPS13_N2	VPS13C VPS13A	4.22e-04	3	223	2	IPR031646
Domain	VPS13_mid_rpt	VPS13C VPS13A	4.22e-04	3	223	2	IPR031642
Domain	VPS13	VPS13C VPS13A	4.22e-04	3	223	2	IPR026847
Domain	VPS13_mid_rpt	VPS13C VPS13A	4.22e-04	3	223	2	PF16910
Domain	VPS13	VPS13C VPS13A	4.22e-04	3	223	2	PF16908
Domain	WD40_repeat	HERC2 WDR1 NSMAF WDR48 NWD1 WDR88 NBEA WDFY4 WDR91 LRBA MAPKBP1	4.45e-04	272	223	11	IPR001680
Domain	WD_REPEATS_1	HERC2 WDR1 NSMAF WDR48 NWD1 WDR88 NBEA WDFY4 WDR91 LRBA MAPKBP1	5.35e-04	278	223	11	PS00678
Domain	PH	KIF1A KIF1B ITK PLCG2 PLEKHH2 FERMT2 FERMT3 PRKD2 RASA1 FERMT1 PLEKHG2	5.35e-04	278	223	11	SM00233
Domain	-	ATP8A2 ATP11C ATP11A ATP13A3	5.47e-04	32	223	4	3.40.1110.10
Domain	-	ATP8A2 ATP11C ATP11A ATP13A3	5.47e-04	32	223	4	2.70.150.10
Domain	WD_REPEATS_2	HERC2 WDR1 NSMAF WDR48 NWD1 WDR88 NBEA WDFY4 WDR91 LRBA MAPKBP1	5.51e-04	279	223	11	PS50082
Domain	WD_REPEATS_REGION	HERC2 WDR1 NSMAF WDR48 NWD1 WDR88 NBEA WDFY4 WDR91 LRBA MAPKBP1	5.51e-04	279	223	11	PS50294
Domain	P_typ_ATPase_c	ATP8A2 ATP11C ATP11A	5.55e-04	14	223	3	IPR032630
Domain	P-type_ATPase_N	ATP8A2 ATP11C ATP11A	5.55e-04	14	223	3	IPR032631
Domain	ATPase_dyneun-rel_AAA	DNAH9 DNAH3 DNAH12	5.55e-04	14	223	3	IPR011704
Domain	AAA_8	DNAH9 DNAH3 DNAH12	5.55e-04	14	223	3	PF12780
Domain	PhoLip_ATPase_C	ATP8A2 ATP11C ATP11A	5.55e-04	14	223	3	PF16212
Domain	PhoLip_ATPase_N	ATP8A2 ATP11C ATP11A	5.55e-04	14	223	3	PF16209
Domain	RasGAP_CS	IQGAP2 NF1 RASA1	5.55e-04	14	223	3	IPR023152
Domain	AAA_5	DNAH9 DNAH3 DNAH12	5.55e-04	14	223	3	PF07728
Domain	RasGAP	IQGAP2 NF1 RASA1	5.55e-04	14	223	3	SM00323
Domain	Dynein_heavy_chain_D4_dom	DNAH9 DNAH3 DNAH12	5.55e-04	14	223	3	IPR024317
Domain	Dynein_heavy_dom-2	DNAH9 DNAH3 DNAH12	5.55e-04	14	223	3	IPR013602
Domain	DHC_N2	DNAH9 DNAH3 DNAH12	5.55e-04	14	223	3	PF08393
Domain	P-type_ATPase_IV	ATP8A2 ATP11C ATP11A	5.55e-04	14	223	3	IPR006539
Domain	PH_domain	KIF1A KIF1B ITK PLCG2 PLEKHH2 FERMT2 FERMT3 PRKD2 RASA1 FERMT1 PLEKHG2	5.67e-04	280	223	11	IPR001849
Domain	RasGAP	IQGAP2 NF1 RASA1	6.87e-04	15	223	3	PF00616
Domain	RAS_GTPASE_ACTIV_2	IQGAP2 NF1 RASA1	6.87e-04	15	223	3	PS50018
Domain	DHC_fam	DNAH9 DNAH3 DNAH12	6.87e-04	15	223	3	IPR026983
Domain	RAS_GTPASE_ACTIV_1	IQGAP2 NF1 RASA1	6.87e-04	15	223	3	PS00509
Domain	Dynein_heavy	DNAH9 DNAH3 DNAH12	6.87e-04	15	223	3	PF03028
Domain	Dynein_heavy_dom	DNAH9 DNAH3 DNAH12	6.87e-04	15	223	3	IPR004273
Domain	ATPase_P-typ_cyto_domN	ATP8A2 ATP11C ATP11A ATP13A3	7.75e-04	35	223	4	IPR023299
Domain	VPS13_C	VPS13C VPS13A	8.38e-04	4	223	2	IPR031645
Domain	Kinesin-like_KIF1-typ	KIF1A KIF1B	8.38e-04	4	223	2	IPR022140
Domain	SHR-BD	VPS13C VPS13A	8.38e-04	4	223	2	IPR009543
Domain	KIF1B	KIF1A KIF1B	8.38e-04	4	223	2	PF12423
Domain	VPS13_C	VPS13C VPS13A	8.38e-04	4	223	2	PF16909
Domain	SHR-BD	VPS13C VPS13A	8.38e-04	4	223	2	PF06650
Domain	ATPase_P-typ_P_site	ATP8A2 ATP11C ATP11A ATP13A3	8.63e-04	36	223	4	IPR018303
Domain	P_typ_ATPase	ATP8A2 ATP11C ATP11A ATP13A3	8.63e-04	36	223	4	IPR001757
Domain	ATPASE_E1_E2	ATP8A2 ATP11C ATP11A ATP13A3	8.63e-04	36	223	4	PS00154
Domain	ANF_lig-bd_rcpt	NPR2 GRIA3 GABBR2 GRM8	9.59e-04	37	223	4	IPR001828
Domain	ANF_receptor	NPR2 GRIA3 GABBR2 GRM8	9.59e-04	37	223	4	PF01094
Domain	ATPase_P-typ_transduc_dom_A	ATP8A2 ATP11C ATP11A ATP13A3	9.59e-04	37	223	4	IPR008250
Domain	E1-E2_ATPase	ATP8A2 ATP11C ATP11A ATP13A3	9.59e-04	37	223	4	PF00122
Domain	WD40	WDR1 NSMAF WDR48 NWD1 WDR88 NBEA WDFY4 WDR91 LRBA MAPKBP1	1.14e-03	259	223	10	PF00400
Domain	Peripla_BP_I	NPR2 GRIA3 GABBR2 GRM8	1.17e-03	39	223	4	IPR028082
Domain	RasGAP_dom	IQGAP2 NF1 RASA1	1.20e-03	18	223	3	IPR001936
Domain	K_chnl_volt-dep_KCNQ_C	KCNQ5 KCNQ2	1.39e-03	5	223	2	IPR013821
Domain	K_chnl_volt-dep_KCNQ	KCNQ5 KCNQ2	1.39e-03	5	223	2	IPR003937
Domain	DUF4704	NBEA LRBA	1.39e-03	5	223	2	IPR031570
Domain	DUF4704	NBEA LRBA	1.39e-03	5	223	2	PF15787
Domain	KCNQ_channel	KCNQ5 KCNQ2	1.39e-03	5	223	2	PF03520
Domain	BBOX	TRIM34 TRIM77 TRIM6 TRIM5 TRIM9	1.40e-03	69	223	5	SM00336
Domain	WD40	WDR1 NSMAF WDR48 NWD1 WDR88 NBEA WDFY4 WDR91 LRBA MAPKBP1	1.48e-03	268	223	10	SM00320
Domain	-	TRIM34 TRIM77 TRIM6 TRIM5 TRIM9	1.59e-03	71	223	5	4.10.45.10
Domain	AAA+_ATPase	ABCA13 ABCA8 DNAH9 DNAH3 ABCB6 DNAH12 ATAD1	1.74e-03	144	223	7	IPR003593
Domain	AAA	ABCA13 ABCA8 DNAH9 DNAH3 ABCB6 DNAH12 ATAD1	1.74e-03	144	223	7	SM00382
Domain	Kinesin_assoc	KIF1A KIF1B	2.06e-03	6	223	2	PF16183
Domain	PH_BEACH	NBEA LRBA	2.06e-03	6	223	2	PF14844
Domain	Kinesin_assoc	KIF1A KIF1B	2.06e-03	6	223	2	IPR032405
Domain	Kinesin-like	KIF1A KIF1B	2.06e-03	6	223	2	IPR022164
Pubmed	A dual-activity topoisomerase complex regulates mRNA translation and turnover.	MYO7A KDM3B ZBED4 SH3TC1 UCKL1 A4GALT KCNQ2 DENND5A HERC2 EPN3 PRKD2 NSD2 KSR2 CHD8 DENND1A ANO8 THADA IGF2R BTBD7 TTLL4 NPRL3 LRBA MAPKBP1 CABIN1 ESPL1 LSM10 SOWAHB HTT MYBL2	2.83e-10	1105	229	29	35748872
Pubmed	In-Depth In Vivo Crosslinking in Minutes by a Compact, Membrane-Permeable, and Alkynyl-Enrichable Crosslinker.	SMG1 AHCYL1 INTU IQGAP2 GATB ACTN2 NEB PSMA8 FER1L6 RPS6KC1 ZBED4 VPS13A SYCP1 DLG3 ATP11C ATP11A VARS1 RGPD5 RGPD8 NSD2 PCDHGA7 GRIA3 APOB HEATR1 ZFC3H1 FAM50A CBX5 TNN AVIL RIMS1	2.83e-08	1442	229	30	35575683
Pubmed	Genome-wide CRISPR screen identifies HNRNPL as a prostate cancer dependency regulating RNA splicing.	INTU KIF1A VPS13C KIF1B SMOC2 KCNIP3 KCNQ5 SH3TC1 UCKL1 SEL1L3 ACSF3 ATP11A DENND5A NSMAF CUL4A RPH3AL RASA1 NSD2 KSR2 DENND1A ANKH ANO8 THADA TBK1 NT5C2 KYAT3 RIMS1 LRBA HTT	1.98e-07	1489	229	29	28611215
Pubmed	Loss of kindlin-1, a human homolog of the Caenorhabditis elegans actin-extracellular-matrix linker protein UNC-112, causes Kindler syndrome.	FERMT2 FERMT3 FERMT1	2.82e-07	3	229	3	12789646
Pubmed	The role of kindlins in cell biology and relevance to human disease.	FERMT2 FERMT3 FERMT1	2.82e-07	3	229	3	19854292
Pubmed	URP1: a member of a novel family of PH and FERM domain-containing membrane-associated proteins is significantly over-expressed in lung and colon carcinomas.	FERMT2 FERMT3 FERMT1	2.82e-07	3	229	3	12697302
Pubmed	The Kindlins: subcellular localization and expression during murine development.	FERMT2 FERMT3 FERMT1	2.82e-07	3	229	3	16876785
Pubmed	Neuron-specific protein network mapping of autism risk genes identifies shared biological mechanisms and disease-relevant pathologies.	AHCYL1 RPS6KC1 SERPINE2 NF1 KCNQ5 KCNQ2 DLG3 FERMT2 NOS1 VARS1 CAP1 RGPD8 DSG1 ATG2B GRIA3 NBEA LRRC4C GABBR2 ANO8 CSE1L ATAD1 TRIM9 CNTNAP2 RIMS1	6.14e-07	1139	229	24	36417873
Pubmed	Construction of long-transcript enriched cDNA libraries from submicrogram amounts of total RNAs by a universal PCR amplification method.	PRAMEF10 IQGAP2 RAPGEF5 RPS6KC1 TAOK3 MAP3K9 P2RY14 ATP11A FERMT2 UBE2Q2 PRAMEF33 ACAD9 APOB HEATR1 NCOA4 WDFY4 TRIM5 IGF2R CBX5 TTLL4 ITPRIP ACCSL ESPL1	9.49e-07	1084	229	23	11544199
Pubmed	An expanded clade of rodent Trim5 genes.	TRIM34 TRIM6 TRIM5	1.12e-06	4	229	3	19147168
Pubmed	Antiretroviral potential of human tripartite motif-5 and related proteins.	TRIM34 TRIM6 TRIM5	1.12e-06	4	229	3	16828831
Pubmed	Determinants of the higher order association of the restriction factor TRIM5alpha and other tripartite motif (TRIM) proteins.	TRIM34 TRIM6 TRIM5	1.12e-06	4	229	3	21680743
Pubmed	CRL4s: the CUL4-RING E3 ubiquitin ligases.	WDR1 CUL4B CUL4A	1.12e-06	4	229	3	19818632
Pubmed	The Functional Proximal Proteome of Oncogenic Ras Includes mTORC2.	AHCYL1 IQGAP2 LEMD3 NF1 PIK3CA GSTA5 DLG3 ATP11A ATP13A3 FERMT2 EPN3 FERMT1 APOB SLC6A9 IGF2R LRBA	1.39e-06	569	229	16	30639242
Pubmed	Spatiotemporal profile of postsynaptic interactomes integrates components of complex brain disorders.	IQGAP2 SLC12A5 NF1 DLG3 HERC2 WDR1 NOS1 FERMT3 RGPD8 KSR2 GRIA3 CHD8 NBEA GABBR2 WDR91 IGF2R TBK1 NT5C2 RIMS1 CABIN1 MTSS2	1.88e-06	963	229	21	28671696
Pubmed	Overlapping Activities of Two Neuronal Splicing Factors Switch the GABA Effect from Excitatory to Inhibitory by Regulating REST.	KIF1A MYO7A VPS13C KIF1B SLC12A5 KCNQ2 TRIM9 RIMS1	2.27e-06	128	229	8	30995482
Pubmed	Kindlin-2 controls TGF-β signalling and Sox9 expression to regulate chondrogenesis.	FERMT2 FERMT3 FERMT1 TGFBR2	2.36e-06	15	229	4	26151572
Pubmed	Multilevel proteomics reveals host perturbations by SARS-CoV-2 and SARS-CoV.	AHCYL1 LEMD3 NT5C3A SERPINE2 NF1 VPS13A ATP11C ATP13A3 RNF145 FKBP3 CAP1 CHD8 APOB NCOA4 TGFBR2 THADA IGF2R TRIM9 FAM50A LRRC8A LRBA TMEM68	2.40e-06	1061	229	22	33845483
Pubmed	Human Type IV P-type ATPases That Work as Plasma Membrane Phospholipid Flippases and Their Regulation by Caspase and Calcium.	ATP8A2 ATP11C ATP11A	2.79e-06	5	229	3	26567335
Pubmed	Prediction of the coding sequences of unidentified human genes. XVIII. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro.	CHD8 NBEA LRRC4C WDFY4 DENND1A ANKH ANO8	4.98e-06	101	229	7	10997877
Pubmed	PLC-gamma2 is essential for formation and maintenance of memory B cells.	PLCG2 IGHG3 IGHG4	5.55e-06	6	229	3	19273623
Pubmed	Functional replacement of the RING, B-box 2, and coiled-coil domains of tripartite motif 5alpha (TRIM5alpha) by heterologous TRIM domains.	TRIM34 TRIM6 TRIM5	5.55e-06	6	229	3	16775307
Pubmed	Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.	TOPAZ1 VPS13C TRIM6 PLCG2 NSMAF STAB2 LRRC4C TRIM5 CNTNAP2	7.56e-06	199	229	9	23382691
Pubmed	Quantitative analysis of HSP90-client interactions reveals principles of substrate recognition.	ITK RPS6KC1 TAOK3 ZBED4 MAP3K9 CUL4B CUL4A PRKD2 KSR2 TBK1 SRPK3 MAPK4	7.63e-06	372	229	12	22939624
Pubmed	E3 ubiquitin ligase RNF123 targets lamin B1 and lamin-binding proteins.	KIF1A MYO7A TOPAZ1 VPS13C LAMA1 RPS6KC1 ZBED4 AGL VPS13A MAP3K9 GALNTL6 DNAH3 NBEA CPT1B TRIM9 TBK1 PRG4	8.90e-06	736	229	17	29676528
Pubmed	KLHL41 stabilizes skeletal muscle sarcomeres by nonproteolytic ubiquitination.	LAMA1 ACTN2 NEB	9.67e-06	7	229	3	28826497
Pubmed	Differences in binding to the ILK complex determines kindlin isoform adhesion localization and integrin activation.	FERMT2 FERMT3 FERMT1	9.67e-06	7	229	3	25086068
Pubmed	Unique features of TRIM5alpha among closely related human TRIM family members.	TRIM34 TRIM6 TRIM5	9.67e-06	7	229	3	17156811
Pubmed	Defining the human deubiquitinating enzyme interaction landscape.	KDM3A AHCYL1 THNSL1 KDM3B TUBGCP3 HERC2 VARS1 RGPD5 WDR48 CUL4B CUL4A PRKD2 DSG1 ACAD9 USP6 IGF2R CSE1L ATAD1 TBK1 PHLPP2	1.28e-05	1005	229	20	19615732
Pubmed	Proximity labeling of endogenous RICTOR identifies mTOR complex 2 regulation by ADP ribosylation factor ARF1.	FKBP3 VARS1 RGPD5 CUL4B CUL4A RGPD8 ATG2B IGF2R HSP90AB2P	1.40e-05	215	229	9	35973513
Pubmed	Defining the proximal interaction networks of Arf GTPases reveals a mechanism for the regulation of PLD1 and PI4KB.	IQGAP2 LEMD3 VPS13C KIF1B KDM3B VPS13A DLG3 FERMT2 TARS1 FERMT1 MUC16 NBEA APOB THADA IGF2R LRBA DKK2	1.78e-05	777	229	17	35844135
Pubmed	Regulation of B cell fate by chronic activity of the IgE B cell receptor.	SYK IGHG3 IGHG4	2.30e-05	9	229	3	27935477
Pubmed	Anti-inflammatory activity of IgG1 mediated by Fc galactosylation and association of FcγRIIB and dectin-1.	SYK IGHG3 IGHG4	2.30e-05	9	229	3	22922409
Pubmed	TNF-α inhibits glucocorticoid receptor-induced gene expression by reshaping the GR nuclear cofactor profile.	SMG1 MYO7A KDM3B SMOC2 NEB FER1L6 NF1 VPS13A MUC16 NBEA USP6 DNAH12 APOL6 OTOP1 MYBL2	2.47e-05	638	229	15	31182584
Pubmed	Synergy between PI3K signaling and MYC in Burkitt lymphomagenesis.	PIK3CA IGHG3 IGHG4	3.27e-05	10	229	3	22897848
Pubmed	Identification of new putative susceptibility genes for several psychiatric disorders by association analysis of regulatory and non-synonymous SNPs of 306 genes involved in neurotransmission and neurodevelopment.	ACTN2 DLG3 PLCG2 NOS1 NPR2 GRIA3 NBEA GABBR2 SLC6A9 CNTNAP2	3.34e-05	300	229	10	19086053
Pubmed	Activities of SYK and PLCgamma2 predict apoptotic response of CLL cells to SRC tyrosine kinase inhibitor dasatinib.	SYK PLCG2	4.32e-05	2	229	2	20068106
Pubmed	The lymphoma-associated fusion tyrosine kinase ITK-SYK requires pleckstrin homology domain-mediated membrane localization for activation and cellular transformation.	ITK SYK	4.32e-05	2	229	2	19535334
Pubmed	Impact of histone demethylase KDM3A-dependent AP-1 transactivity on hepatotumorigenesis induced by PI3K activation.	KDM3A PIK3CA	4.32e-05	2	229	2	28692045
Pubmed	Dysregulation of CUL4A and CUL4B Ubiquitin Ligases in Lung Cancer.	CUL4B CUL4A	4.32e-05	2	229	2	27974468
Pubmed	P2RY14 cAMP signaling regulates Schwann cell precursor self-renewal, proliferation, and nerve tumor initiation in a mouse model of neurofibromatosis.	NF1 P2RY14	4.32e-05	2	229	2	35311647
Pubmed	Differential expression of Kindlin-1 and Kindlin-2 correlates with esophageal cancer progression and epidemiology.	FERMT2 FERMT1	4.32e-05	2	229	2	28667517
Pubmed	Huntingtin recruits KIF1A to transport synaptic vesicle precursors along the mouse axon to support synaptic transmission and motor skill learning.	KIF1A HTT	4.32e-05	2	229	2	37431882
Pubmed	Synapse associated protein 102 (SAP102) binds the C-terminal part of the scaffolding protein neurobeachin.	DLG3 NBEA	4.32e-05	2	229	2	22745750
Pubmed	Discordant evolution of the adjacent antiretroviral genes TRIM22 and TRIM5 in mammals.	TRIM34 TRIM6	4.32e-05	2	229	2	18159944
Pubmed	Replication of association of DENND1A and THADA variants with polycystic ovary syndrome in European cohorts.	DENND1A THADA	4.32e-05	2	229	2	22180642
Pubmed	Neurofibromatosis type I tumor suppressor neurofibromin regulates neuronal differentiation via its GTPase-activating protein function toward Ras.	NF1 RASA1	4.32e-05	2	229	2	12730209
Pubmed	UV-B-induced cutaneous inflammation and prospects for antioxidant treatment in Kindler syndrome.	FERMT2 FERMT1	4.32e-05	2	229	2	27798104
Pubmed	KCNQ2 and KCNQ5 form heteromeric channels independent of KCNQ3.	KCNQ5 KCNQ2	4.32e-05	2	229	2	35320039
Pubmed	Mutations in Cullin 4B result in a human syndrome associated with increased camptothecin-induced topoisomerase I-dependent DNA breaks.	CUL4B CUL4A	4.32e-05	2	229	2	20064923
Pubmed	Intron-less processed Pcdhalpha genes in the central nervous system.	PCDHA8 PCDHA6	4.32e-05	2	229	2	14697259
Pubmed	Newly identified exons encoding novel variants of p94/calpain 3 are expressed ubiquitously and overlap the alpha-glucosidase C gene.	GANC CAPN3	4.32e-05	2	229	2	14675785
Pubmed	Association of atopy and eczema with polymorphisms in T-cell immunoglobulin domain and mucin domain-IL-2-inducible T-cell kinase gene cluster in chromosome 5 q 33.	ITK HAVCR2	4.32e-05	2	229	2	16159638
Pubmed	Activation of the Syk tyrosine kinase is insufficient for downstream signal transduction in B lymphocytes.	SYK PLCG2	4.32e-05	2	229	2	12470302
Pubmed	X-linked hypoparathyroidism region on Xq27 is evolutionarily conserved with regions on 3q26 and 13q34 and contains a novel P-type ATPase.	ATP11C ATP11A	4.32e-05	2	229	2	15533723
Pubmed	Two types of type IV P-type ATPases independently re-establish the asymmetrical distribution of phosphatidylserine in plasma membranes.	ATP11C ATP11A	4.32e-05	2	229	2	36162506
Pubmed	Integrating artificial intelligence in osteosarcoma prognosis: the prognostic significance of SERPINE2 and CPT1B biomarkers.	SERPINE2 CPT1B	4.32e-05	2	229	2	38383657
Pubmed	Oxygen modulates iron homeostasis by switching iron sensing of NCOA4.	HERC2 NCOA4	4.32e-05	2	229	2	37059186
Pubmed	Genotype-phenotype correlations of PCOS susceptibility SNPs identified by GWAS in a large cohort of Han Chinese women.	DENND1A THADA	4.32e-05	2	229	2	23208300
Pubmed	RASA1 and NF1 are Preferentially Co-Mutated and Define A Distinct Genetic Subset of Smoking-Associated Non-Small Cell Lung Carcinomas Sensitive to MEK Inhibition.	NF1 RASA1	4.32e-05	2	229	2	29127119
Pubmed	The tyrosine kinase Syk is required for light chain isotype exclusion but dispensable for the negative selection of B cells.	SYK PLCG2	4.32e-05	2	229	2	15048721
Pubmed	Xid-like phenotypes: a B cell signalosome takes shape.	SYK PLCG2	4.32e-05	2	229	2	10933389
Pubmed	The neuron-specific kinesin superfamily protein KIF1A is a unique monomeric motor for anterograde axonal transport of synaptic vesicle precursors.	KIF1A KIF1B	4.32e-05	2	229	2	7539720
Pubmed	Kindlin-1 and -2 have overlapping functions in epithelial cells implications for phenotype modification.	FERMT2 FERMT1	4.32e-05	2	229	2	21356350
Pubmed	Human and mouse XAP-5 and XAP-5-like (X5L) genes: identification of an ancient functional retroposon differentially expressed in testis.	FAM50B FAM50A	4.32e-05	2	229	2	10534398
Pubmed	Paclitaxel Inhibits KCNQ Channels in Primary Sensory Neurons to Initiate the Development of Painful Peripheral Neuropathy.	KCNQ2 AVIL	4.32e-05	2	229	2	36552832
Pubmed	Binding of the rhesus TRIM5α PRYSPRY domain to capsid is necessary but not sufficient for HIV-1 restriction.	TRIM34 TRIM6	4.32e-05	2	229	2	24314652
Pubmed	ITK/SYK translocation in angioimmunoblastic T-cell lymphoma.	ITK SYK	4.32e-05	2	229	2	24076779
Pubmed	A threonine synthase homolog from a mammalian genome.	THNSL1 THNSL2	4.32e-05	2	229	2	17034760
Pubmed	The relationship between trinucleotide (CAG) repeat length and clinical features of Huntington's disease.	IL12RB2 HTT	4.32e-05	2	229	2	8401589
Pubmed	TBK1 is ubiquitinated by TRIM5α to assemble mitophagy machinery.	TRIM5 TBK1	4.32e-05	2	229	2	38814780
Pubmed	Brain-specific transcript variants of 5' and 3' ends of mouse VPS13A and VPS13C.	VPS13C VPS13A	4.32e-05	2	229	2	17196930
Pubmed	Multidimensional single-cell analysis of BCR signaling reveals proximal activation defect as a hallmark of chronic lymphocytic leukemia B cells.	SYK PLCG2	4.32e-05	2	229	2	24489640
Pubmed	TBK1 phosphorylates mutant Huntingtin and suppresses its aggregation and toxicity in Huntington's disease models.	TBK1 HTT	4.32e-05	2	229	2	32757223
Pubmed	Down-regulated Six2 by knockdown of neurofibromin results in apoptosis of metanephric mesenchyme cells in vitro.	NF1 SIX2	4.32e-05	2	229	2	24573885
Pubmed	KIF1B and NF1 are the most frequently mutated genes in paraganglioma and pheochromocytoma tumors.	KIF1B NF1	4.32e-05	2	229	2	28515046
Pubmed	TRIM34 restricts HIV-1 and SIV capsids in a TRIM5α-dependent manner.	TRIM34 TRIM5	4.32e-05	2	229	2	32282853
Pubmed	TβRII Regulates the Proliferation of Metanephric Mesenchyme Cells through Six2 In Vitro.	TGFBR2 SIX2	4.32e-05	2	229	2	28420207
Pubmed	Investigation of genetic susceptibility factors for human longevity - a targeted nonsynonymous SNP study.	GANC IQGAP2 GCKR AGL SYCP1 CUL4A HELQ PRG4 LRIT1 HTT	4.78e-05	313	229	10	20800603
Pubmed	Quantitative Proteomics Reveals Dynamic Interactions of the Minichromosome Maintenance Complex (MCM) in the Cellular Response to Etoposide Induced DNA Damage.	NEB PSMA8 SYCP1 TARS1 CAP1 RGPD5 CUL4B CUL4A RGPD8 DSG1 MUC16 HEATR1 CSE1L IGHG3 IGHG4 TBK1 HSP90AB2P	5.00e-05	844	229	17	25963833
Pubmed	Prediction of the coding sequences of mouse homologues of KIAA gene: III. the complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.	SMG1 KDM3A VPS13C KDM3B NSD2 TOPBP1 CHD8 ANKH TRIM9 TTLL4 CNTNAP2 LRRC8A ESPL1	5.53e-05	529	229	13	14621295
Pubmed	Differential expression of putative transbilayer amphipath transporters.	ATP8A2 ATP11C ATP11A	7.67e-05	13	229	3	11015572
Pubmed	Mouse screen reveals multiple new genes underlying mouse and human hearing loss.	AHCYL1 PRAMEF10 MYO7A BPNT2 NF1 VPS13A DLG3 ATP11A FKBP3 PRAMEF33 DSG1 ABCB6 GRM8 KCNH4 CBX5 PUS10 TTLL4 DNAH17 MRAP2 LSM10 MTSS2	8.21e-05	1242	229	21	30973865
Pubmed	Prediction of the coding sequences of mouse homologues of KIAA gene: II. The complete nucleotide sequences of 400 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.	INTU RAPGEF5 KIF1B SLC12A5 ZBED4 SEL1L3 DLG3 WDR48 LRRC4C BTBD7 MAPKBP1	9.04e-05	407	229	11	12693553
Pubmed	Identification of dynein heavy chain genes expressed in human and mouse testis: chromosomal localization of an axonemal dynein gene.	DNAH3 DNAH12 DNAH17	9.72e-05	14	229	3	9373155
Pubmed	Rosette-forming glioneuronal tumors share a distinct DNA methylation profile and mutations in FGFR1, with recurrent co-mutation of PIK3CA and NF1.	NF1 PIK3CA	1.29e-04	3	229	2	31250151
Pubmed	Huntingtin associates with the actin cytoskeleton and α-actinin isoforms to influence stimulus dependent morphology changes.	ACTN2 HTT	1.29e-04	3	229	2	30768638
Pubmed	Opposite role of Kindlin-1 and Kindlin-2 in lung cancers.	FERMT2 FERMT1	1.29e-04	3	229	2	23209705
Pubmed	VPS13A and VPS13C are lipid transport proteins differentially localized at ER contact sites.	VPS13C VPS13A	1.29e-04	3	229	2	30093493
Pubmed	Premature terminal differentiation protects from deregulated lymphocyte activation by ITK-Syk.	ITK SYK	1.29e-04	3	229	2	24376268
Pubmed	The BEACH Protein LRBA Promotes the Localization of the Heterotrimeric G-protein Golf to Olfactory Cilia.	NBEA LRBA	1.29e-04	3	229	2	28814779
Pubmed	Cutting Edge: Codeletion of the Ras GTPase-Activating Proteins (RasGAPs) Neurofibromin 1 and p120 RasGAP in T Cells Results in the Development of T Cell Acute Lymphoblastic Leukemia.	NF1 RASA1	1.29e-04	3	229	2	26002977
Pubmed	Vascular system defects and neuronal apoptosis in mice lacking ras GTPase-activating protein.	NF1 RASA1	1.29e-04	3	229	2	7477259
Pubmed	CUL4 E3 ligase regulates the proliferation and apoptosis of lung squamous cell carcinoma and small cell lung carcinoma.	CUL4B CUL4A	1.29e-04	3	229	2	32587774
Pubmed	TRIM9 short isoform preferentially promotes DNA and RNA virus-induced production of type I interferon by recruiting GSK3β to TBK1.	TRIM9 TBK1	1.29e-04	3	229	2	26915459
Pubmed	Src kinase and Syk activation initiate PI3K signaling by a chimeric latent membrane protein 1 in Epstein-Barr virus (EBV)+ B cell lymphomas.	PIK3CA SYK	1.29e-04	3	229	2	22880054
Pubmed	Kindlin-1 and -2 directly bind the C-terminal region of beta integrin cytoplasmic tails and exert integrin-specific activation effects.	FERMT3 FERMT1	1.29e-04	3	229	2	19240021
Pubmed	CUL4high Lung Adenocarcinomas Are Dependent on the CUL4-p21 Ubiquitin Signaling for Proliferation and Survival.	CUL4B CUL4A	1.29e-04	3	229	2	34119472
Pubmed	Glycoprotein VI/Fc receptor gamma chain-independent tyrosine phosphorylation and activation of murine platelets by collagen.	SYK PLCG2	1.29e-04	3	229	2	15283702
Pubmed	Cullin4B/E3-ubiquitin ligase negatively regulates beta-catenin.	CUL4B CUL4A	1.29e-04	3	229	2	17954973
Interaction	CALM1 interactions	KIF1A IQGAP2 MYO7A VPS13C NT5C3A KIF1B KDM3B NUDT9 NEB KCNQ5 ZBED4 PIK3CA VPS13A SYK KCNQ2 DLG3 HERC2 PLEKHH2 FKBP3 CUL4B RASA1 NT5C2 CABIN1 HTT	1.69e-07	626	226	24	int:CALM1
GeneFamily	Fermitins\|Pleckstrin homology domain containing\|FERM domain containing	FERMT2 FERMT3 FERMT1	6.55e-07	3	158	3	561
GeneFamily	WD repeat domain containing\|BEACH domain containing	NSMAF NBEA WDFY4 LRBA	6.84e-07	9	158	4	1230
GeneFamily	Pleckstrin homology domain containing\|Rho guanine nucleotide exchange factors\|C2 domain containing	KIF1A KIF1B ITK PLEKHH2 FERMT2 FERMT3 PRKD2 RASA1 FERMT1 PLEKHG2 PHLPP2	2.01e-06	206	158	11	682
GeneFamily	Dyneins, axonemal	DNAH9 DNAH3 DNAH12 DNAH17	1.22e-05	17	158	4	536
GeneFamily	Ankyrin repeat domain containing\|FERM domain containing	MYO7A PLEKHH2 FERMT2 FERMT3 FERMT1	7.38e-05	50	158	5	1293
GeneFamily	WD repeat domain containing	WDR1 NSMAF WDR48 NWD1 WDR88 NBEA WDFY4 WDR91 LRBA MAPKBP1	1.05e-04	262	158	10	362
GeneFamily	ATPase phospholipid transporting	ATP8A2 ATP11C ATP11A	2.76e-04	15	158	3	1210
GeneFamily	Guanylate cyclase receptors\|DENN/MADD domain containing	DENND5A NPR2 DENND1A	1.31e-03	25	158	3	504
GeneFamily	Ring finger proteins\|Tripartite motif containing\|ARF GTPase family	TRIM34 TRIM77 TRIM6 TRIM5 TRIM9	1.47e-03	95	158	5	59
GeneFamily	CD molecules\|5'-nucleotidases	NT5C3A NT5C2	1.55e-03	7	158	2	1042
GeneFamily	Cullins	CUL4B CUL4A	2.05e-03	8	158	2	1032
GeneFamily	Anoctamins	ANO5 ANO8	3.26e-03	10	158	2	865
GeneFamily	Potassium voltage-gated channels	KCNQ5 KCNQ2 KCNH4	5.10e-03	40	158	3	274
Coexpression	CYCLIN_D1_KE_.V1_DN	KIF1A RAPGEF5 ACTN2 PLCG2 NOS1 FKBP3 DNAH3 DSG1 CHD8 MAPK4	6.97e-06	191	227	10	M2647
Coexpression	GSE16385_UNTREATED_VS_12H_IL4_TREATED_MACROPHAGE_DN	VPS13C CLN5 PLEKHH2 FERMT2 NSMAF ATAD1 FAM50A MTBP PRG4 LRIT1	1.04e-05	200	227	10	M7960
Coexpression	NFE2L2.V2	IQGAP2 GCKR GSTA5 SYK KCNQ2 CHRDL2 NSD2 FERMT1 ABCB6 USP6 PCSK6 SLC47A1 MTBP MRAP2 PRG4	1.62e-05	469	227	15	M2870
ToppCell	COVID-19-kidney-Technical/muscle_(Mes)\|kidney / Disease (COVID-19 only), tissue and cell type	ATP8A2 GREB1L KCNQ5 DNAH9 GALNTL6 DNAH3 NWD1 LRRC4C GABBR2 CNTNAP2 RIMS1	6.65e-10	159	228	11	5335cbcdeaf2bbd0268bbfe0e45c8c0d288e640d
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic-thymocyte\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ABCA13 LAMA1 ANO5 NEB KCNQ2 DNAH9 GALNTL6 OTOA STAB2 APOB LRRC4C	3.12e-09	184	228	11	2cbed6462fea2622871bb7e49b0df3d984239281
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic-proliferating_thymocyte;_DN_to_DP_transition,_dividing_(some_are_Cd8+/_Cd4+,_some_undergoing_VDJ_recombination)\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ABCA13 LAMA1 ANO5 NEB KCNQ2 DNAH9 GALNTL6 OTOA STAB2 APOB LRRC4C	3.12e-09	184	228	11	2b19a8c5f823e00812908b23e66bb4e563278aff
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ABCA13 LAMA1 ANO5 NEB KCNQ2 DNAH9 GALNTL6 OTOA STAB2 APOB LRRC4C	3.12e-09	184	228	11	ea7a7e2bac46d4d2c31a5d576b38a032b5335062
ToppCell	COVID-19-kidney-Technical/muscle_(Imm)\|kidney / Disease (COVID-19 only), tissue and cell type	ATP8A2 GREB1L KCNQ5 DNAH9 GALNTL6 DNAH3 LRRC4C GABBR2 GRM8 CNTNAP2	1.28e-08	163	228	10	19c28ce16a588a7f4a035c32726f6ccd67702b5b
ToppCell	COVID-19-Heart-T_cell\|COVID-19 / Disease (COVID-19 only), tissue and cell type	IL12RB2 ATP8A2 NEB FER1L6 ITK KCNQ5 GALNTL6 LRRC4C TFR2 CNTNAP2	2.03e-08	171	228	10	b2e753e811a7639956994609f73efcdb62d04f82
ToppCell	Smart-start-Cell-Wel_seq-Neoplastic-Stem-like-OPC-like-OPC-like-F\|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	TOPAZ1 FAM151A SYCP1 NXF3 GALNTL6 STAB2 KCNH4 ZNF630 ACCSL SIX2	6.37e-08	193	228	10	315840bc48899f3a36d57b19197509de19716e3d
ToppCell	Primary_Motor_Cortex_(M1)-Neuronal\|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	ATP8A2 SLC12A5 KCNQ5 SLF1 KSR2 GRIA3 NBEA GABBR2 CNTNAP2 RIMS1	8.10e-08	198	228	10	4ca5ff320905ab4ff60ed90a5522227c782142a6
ToppCell	PBMC-Control-Lymphocyte-B-B_cell-B_intermediate-B_intermediate-10\|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	SMOC2 NEB SEL1L3 SYK GALNTL6 WDFY4 IGHG3 IGHG4 MRAP2	4.56e-07	183	228	9	01664fce6b70a02c9d39d747b6a6aabc86d57bc2
ToppCell	Control-Epithelial_cells-Airway_goblet\|Control / group, cell type (main and fine annotations)	ABCA13 FER1L6 FERMT1 MUC16 CP GRIA3 PCSK6 RIMS1 FAM83A	4.77e-07	184	228	9	d92a71441e4e19f8c301999d8186f8e48e3cd162
ToppCell	facs-Aorta-Heart-3m\|Aorta / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	RAPGEF5 PLCG2 HERC2 FERMT3 NSD2 TGFBR2 BTBD7 ITPRIP DKK2	6.81e-07	192	228	9	1ccc47792edf9ee23501c8e2165d11271636b66a
ToppCell	3'-Broncho-tracheal-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.3.0\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	INTU ABCA13 PLCG2 DNAH9 DNAH3 MUC16 NBEA DNAH12 CCDC180	7.43e-07	194	228	9	4a2c127c90d1fefe604fcb9e796577d21b489dd6
ToppCell	Mid-temporal_gyrus_(MTG)-Neuronal\|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	ATP8A2 SLC12A5 KCNQ5 KSR2 GRIA3 NBEA GABBR2 CNTNAP2 RIMS1	8.09e-07	196	228	9	676c56b44ac29f7baecb62f49bb8597cc74c0a88
ToppCell	Parenchymal-NucSeq-Epithelial-Epi_airway_secretory-Secretory_Goblet\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	ABCA13 FER1L6 MUC16 CP NBEA RIMS1 MRAP2 SIX2 FAM83A	8.81e-07	198	228	9	af07a970afaa435c6433bb5c1cbff4c67af350c7
ToppCell	primary_auditory_cortex_(A1C)-Neuronal\|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	ATP8A2 SLC12A5 KCNQ5 KSR2 GRIA3 NBEA GABBR2 CNTNAP2 RIMS1	8.81e-07	198	228	9	6d18b45eda4014759e6dd282d78ffd28df8a6044
ToppCell	Anterior_Cingulate_gyrus_(CgG)-Neuronal\|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	ATP8A2 SLC12A5 KCNQ5 SLF1 KSR2 NBEA GABBR2 CNTNAP2 RIMS1	8.81e-07	198	228	9	0ff30edfd3c133a42e8cb96e1631a1143215f808
ToppCell	Neuronal\|World / cells hierarchy compared to all cells using T-Statistic	ATP8A2 SLC12A5 KCNQ5 SLF1 KSR2 NBEA GABBR2 CNTNAP2 RIMS1	9.57e-07	200	228	9	48d801219bc771d6c7e151dc88ca4c179988de85
ToppCell	LPS-IL1RA-Myeloid_granulocytic-Neutrophils\|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	ATPSCKMT IL12RB2 ABCA13 SYK MAP3K9 ANKH AVIL RIMS1	1.33e-06	154	228	8	43735f7c58cac51855ded486ee8d8729a1b9909e
ToppCell	LPS-IL1RA-Myeloid_granulocytic\|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	ATPSCKMT IL12RB2 ABCA13 SYK MAP3K9 ANKH AVIL RIMS1	1.33e-06	154	228	8	d55fb73461885e1e02061a344ff89624ef4de487
ToppCell	Parenchymal-10x5prime-Epithelial-Epi_submucosal-gland-SMG_Duct\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	KIF1A ABCA13 DLG3 MUC16 CP SLC6A9 RIMS1	1.41e-06	108	228	7	9c7f3e25facfb54ef0be45044999bc36438bbea0
ToppCell	Parenchymal-10x5prime-Epithelial-Epi_submucosal-gland\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	KIF1A ABCA13 DLG3 MUC16 CP SLC6A9 RIMS1	1.41e-06	108	228	7	75d635fc5bb004418db2e1328c24d96b718f10b1
ToppCell	PBMC-Mild-Lymphocyte-B-B_cell-B_intermediate-B_intermediate-10\|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	SMOC2 NEB SEL1L3 SYK GALNTL6 WDFY4 IGHG3 IGHG4	1.46e-06	156	228	8	d81e78bec5c8a3f3ec9e1447ebab2c5805b815eb
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Degenerative_Proximal_Tubule_Epithelial_Cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	ATP8A2 DNAH9 GALNTL6 DNAH3 NWD1 LRRC4C GABBR2 CNTNAP2	2.44e-06	167	228	8	3edb0570e583bb527165bcd8a4c25a042054043b
ToppCell	3'-Broncho-tracheal-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.0.2\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	INTU ABCA13 DNAH9 DNAH3 NWD1 MUC16 NBEA DNAH12	2.66e-06	169	228	8	14aadc2d1bf66eb47dac33b4d61ddb3c942caa4f
ToppCell	facs-Thymus-Flowthrough-3m-Myeloid-macrophage\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ARSK NF1 CEP120 PLCG2 HAVCR2 ATAD1 CCDC180 CTSH	3.04e-06	172	228	8	438d2e7f1897668a14d85ca70722e5d0102606dc
ToppCell	facs-Thymus-Flowthrough-3m-Myeloid\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ARSK NF1 CEP120 PLCG2 HAVCR2 ATAD1 CCDC180 CTSH	3.04e-06	172	228	8	356a66cd9303470e427005cc67fdd22a2c4bf971
ToppCell	facs-Thymus-Flowthrough-3m-Myeloid-macrophage\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ARSK NF1 CEP120 PLCG2 HAVCR2 ATAD1 CCDC180 CTSH	3.04e-06	172	228	8	46fadeee483fdf8402df92ec98575a09c6c15b16
ToppCell	3'-Broncho-tracheal-Epithelial-Epithelial_transtional-secretory-nasal_mucosa_goblet_cell-Goblet_(nasal)-Goblet_(nasal)_L.0.2.2.1\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	ABCA13 DNAH9 NWD1 MUC16 CP NBEA DNAH12 CNTNAP2	3.60e-06	176	228	8	dee780cfa85234a7cd7bf440b66b84cec959893e
ToppCell	3'-Broncho-tracheal-Epithelial-Epithelial_transtional-secretory-nasal_mucosa_goblet_cell-Goblet_(nasal)-Goblet_(nasal)_L.0.2.0.5\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	SMG1 ABCA13 FER1L6 PLCG2 NSD2 MUC16 NBEA RIMS1	4.08e-06	179	228	8	6e965e424eebef50f0202cff75f458be395cfca1
ToppCell	Multiple_Sclerosis-Lymphocyte-B-B_intermediate\|Multiple_Sclerosis / Disease, Lineage and Cell Type	SMOC2 SEL1L3 SYK PLCG2 GALNTL6 WDFY4 IGHG3 CTSH	5.86e-06	188	228	8	ee1bb0700ab70e03a63982446a33976b9200ddb6
ToppCell	Substantia_nigra-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)-Inhibitory_Neuron.Gad1Gad2.Rln3_(parabrachial_pigmented_nucleus_(PBP))\|Substantia_nigra / BrainAtlas - Mouse McCarroll V32	FER1L6 GALNTL6 RPH3AL DNAH17 GZMA ACCSL	6.08e-06	88	228	6	b7b55f51af8ffa82813a4747580985a430da9ed1
ToppCell	Substantia_nigra-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)-Inhibitory_Neuron.Gad1Gad2.Rln3_(parabrachial_pigmented_nucleus_(PBP))-\|Substantia_nigra / BrainAtlas - Mouse McCarroll V32	FER1L6 GALNTL6 RPH3AL DNAH17 GZMA ACCSL	6.08e-06	88	228	6	b4620e79ea80681305434707e87cb02a7c6a5e4f
ToppCell	Substantia_nigra-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)-Inhibitory_Neuron.Gad1Gad2.Rln3_(parabrachial_pigmented_nucleus_(PBP))--\|Substantia_nigra / BrainAtlas - Mouse McCarroll V32	FER1L6 GALNTL6 RPH3AL DNAH17 GZMA ACCSL	6.08e-06	88	228	6	7992f8e621edf464bffcb70a6cc5f3b60c1d96f8
ToppCell	COVID-19-Heart-T_cell\|Heart / Disease (COVID-19 only), tissue and cell type	IQGAP2 ABCA13 ITK KCNQ5 GALNTL6 KSR2 GZMA CNTNAP2	6.33e-06	190	228	8	e6c3a6e01fef6c5b49f72661d4fb0414ba9046bf
ToppCell	facs-Lung-3m-Endothelial-lymphatic_endothelial-lymphatic_endothelial_cell-lymphatic_endothelial_cell\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	MYO7A ATP8A2 STAB2 CP ANKH TGFBR2 PCSK6 ITPRIP	6.33e-06	190	228	8	26e2237f65cb43723c5da853831b40df2982d6e4
ToppCell	Children_(3_yrs)-Immune-interstitial_macrophage_(C1Q_positive)-D032\|Children_(3_yrs) / Lineage, Cell type, age group and donor	MAN1A1 IQGAP2 MYO7A KIF1B SYK P2RY14 DENND1A ANKH	6.33e-06	190	228	8	2d54fca50593fbd11fe13fc2bfaf937a05db776d
ToppCell	facs-Lung-3m-Endothelial-lymphatic_endothelial\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	MYO7A ATP8A2 STAB2 CP ANKH TGFBR2 PCSK6 ITPRIP	6.33e-06	190	228	8	a1514d2186eb4fe569971ab22dc0c17d353fb94a
ToppCell	facs-Lung-3m-Endothelial-lymphatic_endothelial-lymphatic_endothelial_cell\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	MYO7A ATP8A2 STAB2 CP ANKH TGFBR2 PCSK6 ITPRIP	6.33e-06	190	228	8	0bb954a94317cfc742b9b6221bb80f8baa6d3ff1
ToppCell	COVID-19-Epithelial_cells-Airway_goblet\|COVID-19 / group, cell type (main and fine annotations)	ABCA13 FER1L6 GALNTL6 MUC16 CP NBEA RIMS1 FAM83A	6.33e-06	190	228	8	51ca9ef4df3220487152fcf684147730637c7cc1
ToppCell	facs-Lung-nan-3m-Endothelial-Lymphatic_endothelial_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MYO7A ATP8A2 STAB2 CP ANKH TGFBR2 PCSK6 ITPRIP	6.58e-06	191	228	8	48823a97c38263f2c6e58348214f5b62773a6368
ToppCell	Entopeduncular-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)\|Entopeduncular / BrainAtlas - Mouse McCarroll V32	ATP8A2 SLC12A5 PIK3CA KCNQ2 KSR2 GRM8 CNTNAP2 MRAP2	6.58e-06	191	228	8	5d24022cec293bc8d9e978ae99a109e660bb8f83
ToppCell	Entopeduncular-Neuronal-Inhibitory\|Entopeduncular / BrainAtlas - Mouse McCarroll V32	ATP8A2 SLC12A5 PIK3CA KCNQ2 KSR2 GRM8 CNTNAP2 MRAP2	6.58e-06	191	228	8	73dae4cdea86aec62393ad7303dc7375a6b3fc86
ToppCell	facs-Lung-nan-3m-Endothelial-endothelial_cell_of_lymphatic_vessel\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MYO7A ATP8A2 STAB2 CP ANKH TGFBR2 PCSK6 ITPRIP	6.58e-06	191	228	8	0eedc66e967b1837ce2c14f8c14b3c1eba868c76
ToppCell	Bronchial-NucSeq-Epithelial-Epi_airway_secretory-Secretory_Goblet\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	TMPRSS13 ABCA13 HAPLN2 FER1L6 A4GALT MUC16 CP RIMS1	7.37e-06	194	228	8	e0228f593c3493175962a4817500d4337ddc4e88
ToppCell	3'-Broncho-tracheal-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.2.1\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	ABCA13 DNAH9 NWD1 MUC16 CP NBEA DNAH12 RIMS1	7.65e-06	195	228	8	9651ee03738226ee10e901f8b9ec6a417eb9c301
ToppCell	Tracheal-NucSeq-Epithelial-Epi_airway_secretory-Secretory_Goblet\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	ABCA13 FER1L6 A4GALT GALNTL6 MUC16 CP RIMS1 FAM83A	7.94e-06	196	228	8	c366f980cc04abfe1c0c14746c11810c812a42c0
ToppCell	COVID-19-Epithelial-Club,_Basal_cells\|COVID-19 / Condition, Lineage and Cell class	ABCA13 FER1L6 A4GALT MUC16 CP RIMS1 SIX2 FAM83A	7.94e-06	196	228	8	dd32046067d93b9484cfbf1d7826a436a3d9f0e9
ToppCell	mild-Lymphocytic-B_cells_1\|Lymphocytic / Cohort 2 (Rhapsody WB + PBMC) with disease condition, lineage and cell classs	SEL1L3 SYK P2RY14 PLCG2 WDFY4 IGHG3 CNTNAP2 CTSH	7.94e-06	196	228	8	1988088dd7e1ba947339fd1331beed482955e607
ToppCell	AT2_cells-IPF_03\|World / lung cells shred on cell class, cell subclass, sample id	AGL ATP11A RNF145 FERMT1 CP GABBR2 IGHG3 IGHG4	8.24e-06	197	228	8	5e0d222872a25bb9e9069d3dffda2844bb69874a
ToppCell	3'-Broncho-tracheal-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.2.4\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	DNAH9 DNAH3 LRRC34 NWD1 MUC16 NBEA DNAH12 RIMS1	8.24e-06	197	228	8	d83c61d2b5742e463122e1a98c7197a5b5b3d41b
ToppCell	Biopsy_Other_PF-Epithelial-MUC5AC+_High\|Biopsy_Other_PF / Sample group, Lineage and Cell type	ABCA13 FER1L6 GSTA5 MUC16 CP APOB RIMS1 FAM83A	8.55e-06	198	228	8	30e6177e216f66caddcd009fafef0e07369f4d8e
ToppCell	Bronchus_Control_(B.)-Endothelial-TX-Bronchial_vessel\|Bronchus_Control_(B.) / Sample group, Lineage and Cell type	KDM3A IL12RB2 KIF1A SMOC2 SRPK3 MAPK4 ESPL1 SIX2	8.55e-06	198	228	8	dcf334d13e5b0018fee24febccfef91c9e17843b
ToppCell	5'-Airway_Nasal-Epithelial-Epithelial_transtional-secretory-nasal_mucosa_goblet_cell-Goblet_(nasal)-Goblet_(nasal)_L.0.2.2.1\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	ABCA13 DNAH9 DNAH3 NWD1 MUC16 CP NBEA DNAH12	8.55e-06	198	228	8	d0ecace1fad24ce50b0935036fabb07e6c9e372d
ToppCell	Somatosensory_Cortex_(S1)-Neuronal\|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	ATP8A2 SLC12A5 KCNQ5 KSR2 NBEA GABBR2 CNTNAP2 RIMS1	8.55e-06	198	228	8	c01091ef18e096d792ea2a7a715764a5b215355f
ToppCell	Primary_Visual_cortex_(V1C)-Neuronal\|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	ATP8A2 SLC12A5 KCNQ5 KSR2 NBEA GABBR2 CNTNAP2 RIMS1	8.55e-06	198	228	8	8ab40fae14fe02e39bc8c8da187a5cd60c787643
ToppCell	Parenchymal-10x5prime-Epithelial-Epi_airway_secretory-Secretory_Goblet\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	ABCA13 FER1L6 EPN3 MUC16 CP RIMS1 SIX2 FAM83A	8.87e-06	199	228	8	3c3133d0aa65338a576634def13e7f0f5c573a10
ToppCell	Parenchymal-10x5prime-Epithelial-Epi_airway_secretory\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	ABCA13 FER1L6 EPN3 MUC16 CP RIMS1 SIX2 FAM83A	8.87e-06	199	228	8	a706ad5cd5e0dc8d7e925a05e45b07d35963f294
ToppCell	(07)_Ionocytes\|World / shred by cell type by condition	TMPRSS13 IQGAP2 RPS6KC1 PLCG2 RPH3AL MUC16 SLC6A9 LPIN2	8.87e-06	199	228	8	8194777d367405a7840787e977854b5c07e3bd6b
ToppCell	COVID-19-kidney-Technical/muscle\|kidney / Disease (COVID-19 only), tissue and cell type	NOS1 DNAH9 GALNTL6 DNAH3 DSG1 LRRC4C CNTNAP2	1.14e-05	148	228	7	0dbd87078f54ee1c2f8ec64e8bac9dfddb9c181e
ToppCell	PBMC-Control-cDC_2\|Control / Compartment, Disease Groups and Clusters	MAT1A ITK MUC16 TRIM9 GZMA OTUD7A PRG4	1.42e-05	153	228	7	4ee37266b0054f276c7a73ab9220f681b9d74c71
ToppCell	E18.5-Immune-Immune_Lymphocytic_T/NK-Lymphocytic_ILC-NK-NK-NK_G2M\|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	IL12RB2 IQGAP2 KCNIP3 ITK VARS1 AVIL GZMA	2.31e-05	165	228	7	ec16a4979b3f203c9f66ed387a7a17bf3a1d3f86
ToppCell	facs-Marrow-T_cells-18m-Lymphocytic-late_pro_B_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	IL12RB2 SLC12A5 KCNQ5 DENND1A ANO8 LRIT1 MYBL2	2.31e-05	165	228	7	0edd56e8d14eaeced9882dd9206ea93e8f402e8d
ToppCell	facs-Marrow-T_cells-18m-Lymphocytic-late_pro-B_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	IL12RB2 SLC12A5 KCNQ5 DENND1A ANO8 LRIT1 MYBL2	2.31e-05	165	228	7	fa3aadfff6fb1e7f142db333c60c2cba02b17e6c
ToppCell	facs-Heart-LV-24m-Lymphocytic\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SYK NOS1 VARS1 WDFY4 INSL6 SRPK3 CTSH	2.49e-05	167	228	7	4a669eafde3582a451614ad304769b47aa1d9578
ToppCell	droplet-Liver-HEPATOCYTES-1m-Epithelial\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MAT1A GCKR CP APOB TFR2 SLC6A9 PCSK6	2.59e-05	168	228	7	b98af4043dfa5dfa4413e482879fad88de484675
ToppCell	droplet-Liver-HEPATOCYTES-1m-Epithelial-hepatocyte\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MAT1A GCKR CP APOB TFR2 SLC6A9 PCSK6	2.59e-05	168	228	7	073b53d4cee6bc8c5c6fce51cf6cd9c316478f69
ToppCell	droplet-Liver-HEPATOCYTES\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MAT1A GCKR CP APOB TFR2 SLC6A9 PCSK6	2.69e-05	169	228	7	f195467438c589f87224bde7da720dea072d110c
ToppCell	droplet-Liver-HEPATOCYTES-1m\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MAT1A GCKR CP APOB TFR2 SLC6A9 PCSK6	2.69e-05	169	228	7	7785cab967a33560830c394c918d6ce625103858
ToppCell	facs-Heart-LV-24m-Lymphocytic-B_cell\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SYK NOS1 VARS1 WDFY4 INSL6 SRPK3 CTSH	2.69e-05	169	228	7	ae85cef7ef8f761c19f4af2a23fe333641c38a92
ToppCell	facs-Lung-24m-Hematologic-lymphocytic-CD8-positive,_alpha-beta_T_cell-CD8-positive,_alpha-beta_T_cell_l5\|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	ACTN2 ITK TOPBP1 THADA INSL6 PUS10 RIMS1	2.69e-05	169	228	7	a388e53deac861a185c31e9cceddae7bcb344700
ToppCell	facs-Heart-LV-24m-Lymphocytic-B_cell\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SYK NOS1 VARS1 WDFY4 INSL6 SRPK3 CTSH	2.69e-05	169	228	7	c01bc3f2f299109086ded83dc11e98559bf1940c
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-glomerular_mesenchymal_cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	RAPGEF5 KCNQ5 ATP11C FERMT2 NBEA PLEKHG2 TRIM9	2.79e-05	170	228	7	876b84740e15399bfff2b9c7f0b80fd759bbdb3f
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-glomerular_mesenchymal_cell-Mesangial_Cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	RAPGEF5 KCNQ5 ATP11C FERMT2 NBEA PLEKHG2 TRIM9	2.79e-05	170	228	7	1f8738acf439d893880db7e1fdc9b3615ca00c39
ToppCell	Fetal_29-31_weeks-Endothelial-endothelial_cell_of_artery-D062\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	TOPAZ1 ANO5 SERPINE2 A4GALT NOS1 MRAP2 DKK2	3.01e-05	172	228	7	de9b11ab109d04937186c09772cec9105a935f95
ToppCell	LPS-IL1RA-Lymphocytic_NKT-iNKT/MAIT-iNKT-MAIT\|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	IL12RB2 IQGAP2 ITK KCNQ5 PLCG2 HAVCR2 GZMA	3.12e-05	173	228	7	fde1fabb8d13d05998ac3f21ecb1fde6a7a2f337
ToppCell	LPS-IL1RA-Lymphocytic_NKT-iNKT/MAIT\|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	IL12RB2 IQGAP2 ITK KCNQ5 PLCG2 HAVCR2 GZMA	3.12e-05	173	228	7	dcde3252ff96448d3a61039a4948c74ad321a218
ToppCell	Children_(3_yrs)-Epithelial-lung_goblet_cell-D139\|Children_(3_yrs) / Lineage, Cell type, age group and donor	FER1L6 A4GALT EPN3 MUC16 CP NBEA RIMS1	3.12e-05	173	228	7	464267a2ff3f5c387b6c9c6fa4dab135a221f448
ToppCell	droplet-Lung-nan-18m-Lymphocytic-Natural_Killer_T_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	IL12RB2 ATP8A2 ACTN2 ITK FKBP3 INSL6 GZMA	3.24e-05	174	228	7	5b00a795a9dd1a77305fcac5017cb276afdc1a27
ToppCell	droplet-Lung-nan-18m-Lymphocytic-mature_NK_T_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	IL12RB2 ATP8A2 ACTN2 ITK FKBP3 INSL6 GZMA	3.24e-05	174	228	7	3340b44c77f55244e3c2e2ea479d42563f937040
ToppCell	droplet-Liver-HEPATOCYTES-1m-Epithelial-Hepatocyte_(Periportal)\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MAT1A GCKR CP APOB TFR2 SLC6A9 PCSK6	3.36e-05	175	228	7	5c38d4b6c03473d841e6203a7efaa6dcb2d59386
ToppCell	systemic_lupus_erythematosus-flare-Lymphocytic_B-plasmablast-female\|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex	MAN1A1 SEL1L3 MUC16 SLC6A9 TNN ESPL1 MYBL2	3.36e-05	175	228	7	3b5346fba617292de71963b6175e85a4f182fe30
ToppCell	TCGA-Bone_and_Soft_Tissue-Primary_Tumor-Sarcoma-Dedifferentiated_Liposarcoma-4\|TCGA-Bone_and_Soft_Tissue / Sample_Type by Project: Shred V9	IL12RB2 MAN1A1 ABCA8 GASK1B RPH3AL TGFBR2 AVIL	3.36e-05	175	228	7	16849ea8f0985108baa2085f34c3de14a4f9f28b
ToppCell	saliva-Severe-critical_progression_d12-22_with-steroid-Myeloid-Monocytic-Classical_Monocyte\|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)	ATP13A3 NSMAF OTOA ZFC3H1 IGF2R TTLL4	3.41e-05	119	228	6	e6f1b9f29dc8fe6b6132c7885234c385159da393
ToppCell	systemic_lupus_erythematosus-flare-Lymphocytic_B-plasmablast\|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex	MAN1A1 SEL1L3 MUC16 SLC6A9 TNN ESPL1 MYBL2	3.49e-05	176	228	7	dc4e939a07bad21ab36181f9588df3fa662f9a92
ToppCell	Control-B_cells\|Control / group, cell type (main and fine annotations)	KCNQ5 SEL1L3 SYK PLCG2 WDFY4 IGHG3 IGHG4	3.49e-05	176	228	7	9125caa27bf790f6b1b960a86c09b4bcb1b58641
ToppCell	CV-Severe-7\|CV / Virus stimulation, Condition and Cluster	SMG1 IL12RB2 ITK P2RY14 HEATR1 CSE1L HTT	3.49e-05	176	228	7	3de0c7d77210049e5616db21eed1490a17a5ec2d
ToppCell	CV-Severe-7\|Severe / Virus stimulation, Condition and Cluster	SMG1 IL12RB2 ITK P2RY14 DENND1A CSE1L HTT	3.61e-05	177	228	7	82fdd6185b368f54f03de389427cbe3071d21a99
ToppCell	COVID-19-lung-B_cells\|lung / Disease (COVID-19 only), tissue and cell type	KCNQ5 SEL1L3 SYK PLCG2 GALNTL6 WDFY4 IGHG3	3.61e-05	177	228	7	f54691e5558091c1734ab15153a10bff15ed171e
ToppCell	Adult-Immune-enucleated_erythrocyte-D231\|Adult / Lineage, Cell type, age group and donor	TOPAZ1 ACTN2 ZSCAN32 MUC16 GABBR2 TFR2 BBS12	3.61e-05	177	228	7	15ee303fb6caea1fd645c3b777666196ce500a1c
ToppCell	facs-GAT-Fat-3m-Lymphocytic-B_cell\|GAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SYK PLCG2 VARS1 PRKD2 OTOP1 ITPRIP ACCSL	3.75e-05	178	228	7	5b6f7e8a930c239db1f31edfb61b2b9228d28663
ToppCell	Children_(3_yrs)-Immune-B_cell-D046\|Children_(3_yrs) / Lineage, Cell type, age group and donor	KCNQ5 SEL1L3 PLCG2 WDFY4 IGHG3 IGHG4 MYBL2	3.88e-05	179	228	7	31411780f1a44bf2d102f288416e97eacec4b6b6
ToppCell	(5)_Epithelial_cells-(5)_Glands_mucous\|(5)_Epithelial_cells / Oesophagus cell shreds on cell class (v1) and cell subclass (v1)	GASK1B SYCP1 SEL1L3 GALNTL6 MUC16 CP NBEA	4.02e-05	180	228	7	a4118adaf4b09e2ca01b662ed60e7bbf32a24d58
ToppCell	facs-Lung-EPCAM-18m-Lymphocytic-lymphocyte\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ITK KCNQ5 P2RY14 STAB2 CPT1B MAPK4 PRG4	4.02e-05	180	228	7	67b062f2ef7e20f392e00c646f4985c415d40de9
ToppCell	facs-Lung-EPCAM-18m-Lymphocytic-Alox5+_Lymphocyte\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ITK KCNQ5 P2RY14 STAB2 CPT1B MAPK4 PRG4	4.02e-05	180	228	7	b28363626f4d2a552abde3434cc1df2e2121aba5
ToppCell	Epithelial-lung_neuroendocrine_cell_(PNEC)\|World / Lineage, Cell type, age group and donor	KIF1A ATP8A2 ANO5 SMOC2 GREB1L RIMS1 SIX2	4.31e-05	182	228	7	57bf4ffb304324e2e392e196336a530d9f78fe0d
ToppCell	PBMC_fresh-frozen-Severe-critical_convalescent_d42-56-Lymphocytic-Lymphocytic_B-B_cell-B_c04-SOX5-TNFRSF1B\|Severe-critical_convalescent_d42-56 / Compartment, severity and other cell annotations on 10x 3' data (130k)	SEL1L3 SYK PLCG2 GALNTL6 WDFY4 IGHG3 IGHG4	4.31e-05	182	228	7	9c120ddd109103ef6fac9c32b84d16a7624d0580
ToppCell	Children_(3_yrs)-Epithelial-lung_goblet_cell\|Children_(3_yrs) / Lineage, Cell type, age group and donor	FER1L6 SEL1L3 MUC16 CP NBEA RIMS1 FAM83A	4.31e-05	182	228	7	3f1a666fe27dd7529c114539ed5f6b8ca585c875
ToppCell	severe_influenza-B_intermediate\|World / disease group, cell group and cell class (v2)	SMOC2 SEL1L3 GALNTL6 LRRC4C WDFY4 IGHG3 IGHG4	4.31e-05	182	228	7	e633a908a2fb30ed362cf22fbb8d6839f31f1751
ToppCell	facs-Lung-EPCAM-3m-Epithelial-Basal\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TMPRSS13 FERMT1 LRRC4C NRBP2 KYAT3 SIX2 SOWAHB	4.47e-05	183	228	7	ecac1cfaff7553a60305b34d6cede6973ffb5430
ToppCell	COVID-19-B_cells\|COVID-19 / group, cell type (main and fine annotations)	MAN1A1 KCNQ5 SEL1L3 PLCG2 IGHG3 IGHG4 MYBL2	4.47e-05	183	228	7	2c016bb59f131a0e821853b085289a3583f0a729
Disease	Colorectal Carcinoma	ABCA13 LAMA1 ABCA8 SLC12A5 NF1 KCNQ5 SH3TC1 PIK3CA VPS13A DLG3 ATP11C P2RY14 DNAH3 ABCB6 APOB KCNH4 TGFBR2 CSE1L ATAD1 CBX5 PUS10 ZSCAN16 CTSH	4.15e-09	702	222	23	C0009402
Disease	Autistic Disorder	KIF1A NF1 CP CHD8 NBEA GABBR2 GRM8 WDFY4 CNTNAP2 RIMS1	3.12e-05	261	222	10	C0004352
Disease	mean platelet volume	IQGAP2 CYP21A2 KIF1B GCKR SMOC2 SERPINE2 ZBED4 A4GALT SYK DLG3 ATP13A3 PLCG2 RNF145 FERMT3 CUL4A PCDHGA7 TRIM5 LRRC8A ITPRIP ESPL1 HTT	3.25e-05	1020	222	21	EFO_0004584
Disease	Parkinson's disease 23 (implicated_via_orthology)	VPS13C VPS13A	5.64e-05	2	222	2	DOID:0060896 (implicated_via_orthology)
Disease	choreaacanthocytosis (implicated_via_orthology)	VPS13C VPS13A	5.64e-05	2	222	2	DOID:0050766 (implicated_via_orthology)
Disease	Chronic Lymphocytic Leukemia	PIK3CA SYK PLCG2 PRKD2 TOPBP1	5.90e-05	55	222	5	C0023434
Disease	common carotid intimal medial thickness	ATPSCKMT ATP8A2 APOB GRM8 CNTNAP2	1.52e-04	67	222	5	EFO_0004860
Disease	autosomal recessive spinocerebellar ataxia 4 (implicated_via_orthology)	VPS13C VPS13A	1.68e-04	3	222	2	DOID:0111611 (implicated_via_orthology)
Disease	Cohen syndrome (implicated_via_orthology)	VPS13C VPS13A	1.68e-04	3	222	2	DOID:0111590 (implicated_via_orthology)
Disease	diverticulitis	BPNT2 NBEA LRRC4C LSM10	1.70e-04	37	222	4	EFO_1001460
Disease	childhood trauma measurement, alcohol consumption measurement	INTU PCDHGA7 KSR2 LRRC4C GABBR2	2.00e-04	71	222	5	EFO_0007878, EFO_0007979
Disease	very low density lipoprotein cholesterol measurement, cholesterol:total lipids ratio	GCKR CAPN3 APOB TRIM5 IGF2R PCSK6 LRBA HTT	2.94e-04	222	222	8	EFO_0008317, EFO_0020943
Disease	stromal cell-derived factor 1 alpha measurement	CYP21A2 ACSF3 TGFBR2 THADA	3.06e-04	43	222	4	EFO_0008293
Disease	frontal pole volume measurement	KCNQ5 SYK NOS1	3.15e-04	18	222	3	EFO_0010304
Disease	triglycerides:total lipids ratio, very low density lipoprotein cholesterol measurement	GCKR ABCA8 CAPN3 APOB TRIM5 IGF2R PCSK6 LRBA	3.22e-04	225	222	8	EFO_0008317, EFO_0020947
Disease	hepatocyte growth factor measurement	BPNT2 SERPINE2 OTUD7A HTT	3.34e-04	44	222	4	EFO_0006903
Disease	Fc receptor-like protein 4 measurement	SERPINE2 PCSK6	3.35e-04	4	222	2	EFO_0801599
Disease	urinary sodium to creatinine ratio	CYP21A2 GCKR	3.35e-04	4	222	2	EFO_0009883
Disease	response to carbamazepine	INTU TRIM9	3.35e-04	4	222	2	EFO_0008484
Disease	platelet-derived growth factor subunit b measurement	SERPINE2 PCSK6	3.35e-04	4	222	2	EFO_0020650
Disease	Chediak-Higashi syndrome (implicated_via_orthology)	NSMAF WDFY4	3.35e-04	4	222	2	DOID:2935 (implicated_via_orthology)
Disease	UDP-glucuronosyltransferase 2A1 measurement	SERPINE2 PCSK6	3.35e-04	4	222	2	EFO_0802186
Disease	synucleinopathy (biomarker_via_orthology)	KIF1A KIF1B	3.35e-04	4	222	2	DOID:0050890 (biomarker_via_orthology)
Disease	glia-derived nexin measurement	SERPINE2 PCSK6	3.35e-04	4	222	2	EFO_0020403
Disease	metabolite measurement	CYP21A2 GCKR SLC12A5 PLEKHH2 HERPUD2 RPH3AL WDFY4 TGFBR2 IGF2R KYAT3 SLC47A1 TMEM68 CABIN1	3.51e-04	560	222	13	EFO_0004725
Disease	Gastric Adenocarcinoma	ITK MAP3K9 PRKD2 TGFBR2	3.65e-04	45	222	4	C0278701
Disease	triacylglycerol 54:4 measurement	ATP8A2 GCKR APOB GABBR2	3.97e-04	46	222	4	EFO_0010422
Disease	very low density lipoprotein cholesterol measurement, free cholesterol:total lipids ratio	GCKR ABCA8 CAPN3 APOB TRIM5 IGF2R PCSK6 HTT	4.81e-04	239	222	8	EFO_0008317, EFO_0020945
Disease	cytotoxicity measurement, response to metformin	KIF1A SH3TC1 THNSL2	5.06e-04	21	222	3	EFO_0006952, GO_1901558
Disease	acute myeloid leukemia (is_marker_for)	NF1 FERMT2 FERMT3 TFR2	5.07e-04	49	222	4	DOID:9119 (is_marker_for)
Disease	fasting blood glucose measurement, glucose tolerance test, fasting blood insulin measurement	VPS13C GCKR	5.55e-04	5	222	2	EFO_0004307, EFO_0004465, EFO_0004466
Disease	X-23639 measurement	KIF1A KYAT3	5.55e-04	5	222	2	EFO_0800853
Disease	1-myristoyl-2-docosahexaenoyl-GPC (14:0/22:6) measurement	GCKR GREB1L	5.55e-04	5	222	2	EFO_0800454
Disease	severe acute respiratory syndrome, COVID-19	TMPRSS13 MYO7A ATP8A2 SMOC2 ATP11A PCDHA6 LRRC4C HELQ WDFY4 TGFBR2 PCSK6	6.18e-04	447	222	11	EFO_0000694, MONDO_0100096
Disease	mean corpuscular hemoglobin concentration	INTU IQGAP2 CYP21A2 TRIM34 GCKR NEB PIK3CA A4GALT VPS13A CUL4A NCOA4 SERPINA2 TFR2 SLC6A9 INSL6 CBX5 TBK1 NT5C2 NPRL3	7.40e-04	1105	222	19	EFO_0004528
Disease	2-myristoyl-GPC (14:0) measurement	GCKR GREB1L	8.29e-04	6	222	2	EFO_0800242
Disease	1-myristoyl-GPC (14:0) measurement	GCKR GREB1L	8.29e-04	6	222	2	EFO_0800221
Disease	free cholesterol to total lipids in large HDL percentage	GCKR SLC12A5 APOB TRIM5	8.43e-04	56	222	4	EFO_0022279
Disease	Brain Diseases	MAT1A KCNQ2 CP	8.55e-04	25	222	3	C0006111
Disease	very low density lipoprotein cholesterol measurement, cholesteryl esters:total lipids ratio	GCKR ABCA8 CAPN3 APOB TRIM5 IGF2R PCSK6 HTT	9.19e-04	264	222	8	EFO_0008317, EFO_0020944
Disease	triglycerides:total lipids ratio, low density lipoprotein cholesterol measurement	GCKR CAPN3 APOB PCSK6 LRBA HTT	9.86e-04	150	222	6	EFO_0004611, EFO_0020947
Disease	reticulocyte count	IQGAP2 GCKR SLC12A5 GREB1L A4GALT VPS13A ATP11A PLCG2 FERMT3 ABCB6 SERPINA2 TFR2 THADA TBK1 DNAH17 NT5C2 NPRL3 MYBL2	9.98e-04	1045	222	18	EFO_0007986
Disease	autism spectrum disorder (implicated_via_orthology)	TAOK3 CHD8 NBEA CNTNAP2 RIMS1 LRBA	1.06e-03	152	222	6	DOID:0060041 (implicated_via_orthology)
Disease	Encephalopathies	MAT1A KCNQ2 CP	1.08e-03	27	222	3	C0085584
Disease	T-cell immunoglobulin and mucin domain 1 measurement	ABCA8 ITK	1.15e-03	7	222	2	EFO_0010812
Disease	Hyperplasia	MAT1A PIK3CA PRG4	1.20e-03	28	222	3	C0020507
Disease	Child Development Disorders, Specific	KIF1A KCNQ2 WDFY4	1.33e-03	29	222	3	C0085997
Disease	Child Development Deviations	KIF1A KCNQ2 WDFY4	1.33e-03	29	222	3	C0085996
Disease	obsolete_red blood cell distribution width	NT5C3A CYP21A2 GCKR TAOK3 A4GALT VPS13A ATP11C ATP11A CUL4A FBXO48 NPR2 ABCB6 APOB NCOA4 SERPINA2 TRIM5 TFR2 LPIN2 NT5C2 SLC47A1 MYBL2	1.35e-03	1347	222	21	EFO_0005192
Disease	Developmental Disabilities	KIF1A KCNQ2 WDFY4	1.47e-03	30	222	3	C0008073
Disease	neurexophilin-1 measurement	SERPINE2 PCSK6	1.53e-03	8	222	2	EFO_0008244
Disease	hepatitis A virus cellular receptor 2 measurement	ITK HAVCR2	1.53e-03	8	222	2	EFO_0008151
Disease	Myopathies, Nemaline	NEB SRPK3	1.53e-03	8	222	2	C0206157
Disease	cerebellar ataxia (implicated_via_orthology)	VPS13C VPS13A	1.53e-03	8	222	2	DOID:0050753 (implicated_via_orthology)
Disease	apolipoprotein B measurement	GCKR ABCA8 NF1 PLEKHH2 NSMAF APOB TRIM5 TFR2 HAVCR2 THADA IGF2R PCSK6 HTT	1.64e-03	663	222	13	EFO_0004615
Disease	very low density lipoprotein cholesterol measurement, phospholipids:total lipids ratio	CYP21A2 GCKR ABCA8 CAPN3 APOB TRIM5 IGF2R HTT	1.70e-03	291	222	8	EFO_0008317, EFO_0020946
Disease	late-onset Alzheimers disease	IQGAP2 RAPGEF5 ABCA8 PLCG2 FERMT2 KSR2 HAVCR2 PCSK6	1.74e-03	292	222	8	EFO_1001870
Disease	lifestyle measurement, alcohol consumption measurement	INTU ATP8A2 DENND1A LRBA SIX2	1.81e-03	115	222	5	EFO_0007878, EFO_0010724
Disease	creatinine measurement, glomerular filtration rate	CYP21A2 GCKR UBE2Q2 THADA SLC47A1	1.95e-03	117	222	5	EFO_0004518, EFO_0005208
Disease	Hepatocellular carcinoma	PIK3CA IGF2R	1.96e-03	9	222	2	cv:C2239176
Disease	level of Sterol ester (27:1/16:1) in blood serum	GCKR DENND1A	1.96e-03	9	222	2	OBA_2045190
Disease	HEPATOCELLULAR CARCINOMA	PIK3CA IGF2R	1.96e-03	9	222	2	114550
Disease	non-syndromic X-linked intellectual disability (implicated_via_orthology)	DLG3 THADA	1.96e-03	9	222	2	DOID:0050776 (implicated_via_orthology)
Disease	2R,3R-dihydroxybutyrate measurement	KIF1A CYP21A2	1.96e-03	9	222	2	EFO_0800314
Disease	visual epilepsy (implicated_via_orthology)	KDM3B GRM8 CNTNAP2	2.12e-03	34	222	3	DOID:11832 (implicated_via_orthology)
Disease	serum IgG glycosylation measurement	INTU TOPAZ1 VPS13C TRIM6 PLCG2 NSMAF STAB2 LRRC4C TRIM5 IGHG4 CNTNAP2	2.16e-03	523	222	11	EFO_0005193
Disease	Intellectual Disability	ATP8A2 LAMA1 KDM3B NF1 KCNQ5 NSD2 CHD8 NBEA NT5C2 HTT	2.19e-03	447	222	10	C3714756
Disease	creatinine measurement, chronic kidney disease	CYP21A2 GCKR UBE2Q2	2.30e-03	35	222	3	EFO_0003884, EFO_0004518
Disease	level of Triacylglycerol (51:3) in blood serum	GCKR APOB	2.44e-03	10	222	2	OBA_2045163
Disease	long QT syndrome (implicated_via_orthology)	KCNQ5 KCNQ2	2.44e-03	10	222	2	DOID:2843 (implicated_via_orthology)
Disease	reticulocyte measurement	IQGAP2 GCKR PIK3CA VPS13A ATP11A PLCG2 FERMT3 CUL4A ABCB6 SERPINA2 TFR2 TBK1 DNAH17 LPIN2 NT5C2 NPRL3 MYBL2	2.70e-03	1053	222	17	EFO_0010700
Disease	cholesteryl esters to total lipids in medium LDL percentage	GCKR APOB IGF2R	2.70e-03	37	222	3	EFO_0022252
Disease	platelet measurement	IQGAP2 CYP21A2 KIF1B GCKR SERPINE2 PLCG2 RNF145 CBX5	2.78e-03	315	222	8	EFO_0005036
Disease	autosomal dominant nonsyndromic deafness (is_implicated_in)	GREB1L ATP11A	2.96e-03	11	222	2	DOID:0050564 (is_implicated_in)
Disease	level of Diacylglycerol (18:1_18:1) in blood serum	GCKR APOB	2.96e-03	11	222	2	OBA_2045170
Disease	citrate measurement	CYP21A2 CAPN3 ANKH IGF2R	3.02e-03	79	222	4	EFO_0010114
Disease	mean reticulocyte volume	INTU IQGAP2 NT5C3A GCKR NEB PIK3CA VPS13A ACSF3 CUL4A SERPINA2 TFR2 THADA LPIN2 NPRL3	3.08e-03	799	222	14	EFO_0010701
Disease	complement C1q tumor necrosis factor-related protein 1 measurement	SERPINA2 CTSH	3.54e-03	12	222	2	EFO_0801493
Disease	nervous system disease (implicated_via_orthology)	KIF1A KIF1B	3.54e-03	12	222	2	DOID:863 (implicated_via_orthology)
Disease	Hereditary hemochromatosis	CP TFR2	3.54e-03	12	222	2	C0392514
Disease	1-myristoyl-2-arachidonoyl-GPC (14:0/20:4) measurement	GCKR GREB1L	3.54e-03	12	222	2	EFO_0800453
Disease	Hemochromatosis	CP TFR2	3.54e-03	12	222	2	C0018995
Disease	aspartate aminotransferase measurement	IQGAP2 MYO7A ANO5 GCKR NF1 SH3TC1 VARS1 PRKD2 SERPINA2 TRIM5 WDR91 IGHG3 CNTNAP2 LRBA CTSH	3.69e-03	904	222	15	EFO_0004736
Disease	free cholesterol measurement, low density lipoprotein cholesterol measurement	GCKR FAM50B APOB TFR2 IGF2R	3.86e-03	137	222	5	EFO_0004611, EFO_0008591
Disease	autistic disorder (is_implicated_in)	NF1 GRM8 CNTNAP2	3.89e-03	42	222	3	DOID:12849 (is_implicated_in)
Disease	Parkinson Disease	NOS1 CP IGF2R CNTNAP2	3.92e-03	85	222	4	C0030567
Disease	free cholesterol:total lipids ratio, intermediate density lipoprotein measurement	GCKR CAPN3 APOB PCSK6	4.09e-03	86	222	4	EFO_0008595, EFO_0020945
Disease	liver fat measurement	GCKR HAVCR2 CNTNAP2	4.15e-03	43	222	3	EFO_0010821
Disease	BMI-adjusted waist-hip ratio, sex interaction measurement	IQGAP2 LEMD3 FERMT2	4.15e-03	43	222	3	EFO_0007788, EFO_0008343
Disease	triglycerides in large LDL measurement	GCKR APOB IGF2R	4.15e-03	43	222	3	EFO_0022319
Disease	cholesteryl esters to total lipids in small HDL percentage	GCKR APOB PCSK6	4.15e-03	43	222	3	EFO_0022254
Disease	amyotrophic lateral sclerosis (biomarker_via_orthology)	KIF1B IGF2R	4.16e-03	13	222	2	DOID:332 (biomarker_via_orthology)
Disease	developmental and epileptic encephalopathy (implicated_via_orthology)	KCNQ5 KCNQ2	4.16e-03	13	222	2	DOID:0112202 (implicated_via_orthology)
Disease	Prader-Willi Syndrome	HERC2 MRAP2	4.16e-03	13	222	2	C0032897
Disease	level of Phosphatidylcholine (16:1_18:1) in blood serum	GCKR GREB1L	4.16e-03	13	222	2	OBA_2045082
Disease	transmembrane protein 87B measurement	SERPINE2 PCSK6	4.16e-03	13	222	2	EFO_0802158
Disease	Fetal Alcohol Spectrum Disorders	PIK3CA NOS1	4.16e-03	13	222	2	C2985290
Disease	Brittle diabetes	NOS1 CP CTSH	4.43e-03	44	222	3	C0342302
Disease	Diabetes Mellitus, Sudden-Onset	NOS1 CP CTSH	4.43e-03	44	222	3	C4554117
Disease	Diabetes, Autoimmune	NOS1 CP CTSH	4.43e-03	44	222	3	C0205734

Protein segments in the cluster

Peptide	Gene	Start	Entry
LESLDYKGHVNWEIL	PRAMEF33	416	A0A0G2JMD5
EWYTKSHGLLVQQAL	NT5C3A	151	Q9H0P0
HNRSSGLYVWINLKK	ACCSL	476	Q4AC99
TSLYWLEKVSHDAIK	ARSK	226	Q6UWY0
VASLLSQDIHFWIGK	AVIL	51	O75366
PQASAWKKLELSHEY	CHD8	791	Q9HCK8
FRQKASTHETWAYGK	ACTN2	406	P35609
ASKAHSIGVWQDILY	ANO5	721	Q75V66
EYLLKWKGFSEEHNT	CBX5	36	P45973
VRDAVDWVHYKGSLK	NT5C2	201	P49902
TYAVHVWNKKSQGTR	A4GALT	311	Q9NPC4
GYDLATLSKEWKHLK	APOL6	246	Q9BWW8
DGKVAKINWHYADSL	ATP13A3	781	Q9H7F0
DSGKNWRHVYKALTL	EPN3	66	Q9H201
GVYILLSKKHLNWII	GZMA	241	P12544
LKTHWTLDKYGVQAD	FERMT1	71	Q9BQL6
DKKHYILNGSKVWIT	ACAD9	201	Q9H845
YIKEFHTTGLAWSKT	CAP1	196	Q01518
TLAKVWYNQKGFHSL	ABCA13	4391	Q86UQ4
IKYQGLEWKSSASLV	ABCB6	481	Q9NP58
KVTSWVLNTFLGYLK	GATB	421	O75879
EKWKNITGHTLLERY	ACSF3	341	Q4G176
GYKVSALEVEWHLLA	ACSF3	481	Q4G176
DSHALYAKKLWTAPE	NPR2	676	P20594
KDSWKQSLHTIQGLY	CCDC180	1686	Q9P1Z9
VWKDATYSSKARLHV	DKK2	241	Q9UBU2
TVLKFLANGWQKYLS	BBS12	586	Q6ZW61
KEVSLVWHLYGGKDF	ATG2B	1551	Q96BY7
QFSYLEKLLLVHGAW	ATP8A2	856	Q9NTI2
LVSVSAEGYKKLAIW	ANO8	406	Q9HCE9
DYTLHLWNLLSGQEK	NWD1	931	Q149M9
KDSGQNAWLSYLLLK	PCDHGA7	596	Q9Y5G6
WFHGKISKQEAYNLL	RASA1	351	P20936
LVHWAKYLQKTGSGL	RGPD5	576	Q99666
LVHWAKYLQKTGSGL	RGPD8	576	O14715
KSHRQDYLVGNKLSW	GSTA5	141	Q7RTV2
DYLVGNKLSWADIHL	GSTA5	146	Q7RTV2
TALTRAWKGIAHKYE	ITPRIP	306	Q8IWB1
LAAWKVGSGQLHYSV	PCDHA6	21	Q9UN73
AQLTGLKELWLYHTA	LRRC8A	466	Q8IWT6
LKELWLYHTAAKIEA	LRRC8A	471	Q8IWT6
LHGSWFDGKLVTVKY	LEMD3	851	Q9Y2U8
TTWDYASDHGEKKLI	CP	31	P00450
GWAKSQVIILSAKYL	OTOA	436	Q7RTW8
SIAYALKNVSGKIWD	NXF3	161	Q9H4D5
LYWKLSQLTHGITEL	MUC16	13411	Q8WXI7
LAAWKVGSGQLHYSV	PCDHA8	21	Q9Y5H6
KTNLTFSHIYIWGNK	LRRC34	376	Q8IZ02
NIVKLHKYWLDTSEA	NRBP2	101	Q9NSY0
KVTYTDRWGHQVKLD	LSM10	56	Q969L4
LWGSKAHAETSYEKV	MAGEA9	271	P43362
WEVLNLTGVYSGKKH	MAGEB16	226	A2A368
VVAKVGHLYAAWKFS	HAPLN2	271	Q9GZV7
HAEGGKLWSYISKFL	RPS6KC1	406	Q96S38
STVTGVHKYKWLKQN	HERC2	1611	O95714
YKWGSVTHQSVGVVK	HERC2	2656	O95714
YSEPKLILDLSHWKQ	MAPK4	451	P31152
GKKFDTLWQLVEHYS	SYK	231	P43405
FYKSLTNDWKDHLAV	HSP90AB2P	226	Q58FF8
DLKNGATHYWSLEKL	KIF1B	831	O60333
TWKLLGSVVYAHSKE	KCNQ5	251	Q9NR82
DLGNSIKHRFSTKYW	KSR2	406	Q6VAB6
EFQISSKLHLYKGSW	IL12RB2	291	Q99665
DLSLGDYSLLWKAHK	CYP21A2	106	P08686
KGAILSLLGHYKWEK	GRIA3	146	P42263
KLKEWSLILYGTAEH	PCSK6	621	P29122
GTWKLLGSVVYAHSK	KCNQ2	216	O43526
WVDINDKLKLYASHS	NUDT9	311	Q9BW91
YPIWEDFNSKATKLH	MTSS2	26	Q765P7
QLAAHLVYWGKAIII	NPRL3	311	Q12980
HLLKYNVGDLVWSKV	NSD2	216	O96028
KSKVKHEWLSGRYSN	FBXO48	111	Q5FWF7
WLSKKSTYQALLDSV	GANC	36	Q8TET4
GHWYDLKDTSKITLV	DNAH12	1986	Q6ZR08
GALWHIYAAKDAEKI	KDM3B	1611	Q7LBC6
HYSVSKAIWDGLILL	KCNH4	221	Q9UQ05
EGWVVHYSNKDTLRK	PRKD2	401	Q9BZL6
KILAYTEGLHGKWLF	LRBA	2121	P50851
YAARWVAKSLVKAGL	MAT1A	296	Q00266
LVLVNAVYFKGLWKS	SERPINE2	181	P07093
LHSQGVLKNKWSILY	TUBGCP3	81	Q96CW5
ALLHSWASAEKPYLK	FAM83A	116	Q86UY5
NGAFVYLSKLKELWL	LRRC4C	141	Q9HCJ2
AWKYSTDVKLSLNIL	OTUD7A	611	Q8TE49
YHGWTRTTKIKFDDV	PLCG2	371	P16885
IYLWKLVKGIFHLTQ	CHRDL2	366	Q6WN34
KSTEYKVIGHWTNQL	GRM8	481	O00222
IVHYAILGIQKWSSK	GREB1L	1661	Q9C091
IHVTYIKKWDICAGN	BPNT2	291	Q9NX62
DYNTKNGTIKWHSIR	DSG1	31	Q02413
GLLTKVKHGYSKRVW	PLEKHH2	816	Q8IVE3
TLHQWLKDKNKGEIY	PIK3CA	876	P42336
YHSVSLVWKAPQAKN	LRIT1	441	Q9P2V4
LKDTELIYGAKHAWR	NOS1	401	P29475
LSVKLWYDKVGHQLI	RIMS1	746	Q86UR5
STSLEKKGHVYLVGW	GCKR	321	Q14397
SLLLNGKQIHVAYWK	INTU	366	Q9ULD6
GKQIHVAYWKESDKL	INTU	371	Q9ULD6
GLENWLLKSEKSSYQ	NCOA4	256	Q13772
YVLWKNIGRKVDSHQ	OTOP1	286	Q7RTM1
QLKEAYKWITHPLFS	PUS10	181	Q3MIT2
SSVKLTWGTYQQLLK	GASK1B	326	Q6UWH4
APHLEEKAWSKYQTV	SERPINA2	376	P20848
KLALWGEHTGQLYSK	APOB	1916	P04114
QLYWTHQKVTKGVSL	ESPL1	866	Q14674
SYKLGQVSIHSVWLG	HTT	2611	P42858
GALWHIYAAKDTEKI	KDM3A	1171	Q9Y4C1
STDVNLWYKIGHVAL	CABIN1	121	Q9Y6J0
LSKQDHYDWGLRAIK	DNAH17	2011	Q9UFH2
ARWLGTLDKKLEHYS	DNAH17	3941	Q9UFH2
HGYWFDKKDTTRLDI	DNAH3	2166	Q8TD57
SATKSKLHYKQQWGR	CEP120	836	Q8N960
DALEVTWYHAANSKK	FAM151A	66	Q8WW52
SHAGKVVLRSWYEKN	FAM50A	301	Q14320
AFYLGKHSGRKLQWQ	CUL4A	556	Q13619
VHVKGTNVWVALYKN	COL8A2	626	P25067
KLLPEHAQTLEKYSW	F8A1;	286	P23610
KKGDVVHCWYTGTLQ	FKBP3	126	Q00688
WTHAGILLKHKYSFL	ANKH	146	Q9HCJ1
KIKQIIEDQSGHYIW	DLG3	796	Q92796
KQGKSALWSHLLHYQ	DENND5A	811	Q6IQ26
QDILKYLIKWGEHQL	BTBD7	461	Q9P203
SFAEIKHKYLWSEPQ	CTSH	86	P09668
GNRHIKFWYLDDSKT	MAPKBP1	196	O60336
LTYIAEWKGGLLEHK	MAN1A1	456	P33908
GSDKLYHQWLSTVRK	DENND1A	396	Q8TEH3
KHYQWKRVGTLTQDV	GABBR2	191	O75899
LHEWIDLIFGYKQKG	NSMAF	506	Q92636
QWRKDAGFLSYKDHL	CNTNAP2	751	Q9UHC6
LTVLHQDWLNGKEYK	IGHG3	236	P01860
LTVLHQDWLNGKEYK	IGHG4	186	P01861
NWTVGKLKTHLSNVY	HERPUD2	31	Q9BSE4
LSKNGEWYEVLKIAA	HEATR1	566	Q9H583
KQDHYDWGLRAIKSV	DNAH9	2036	Q9NYC9
GHWYDRSKLSLKEIT	DNAH9	2571	Q9NYC9
KGIEKLYEWQHTCLT	HELQ	331	Q8TDG4
HWTLDKYGIQADAKL	FERMT2	76	Q96AC1
WSALLEKAYAKLHGS	CAPN3	201	P20807
GTVHEKLKWAFNLYD	KCNIP3	161	Q9Y2W7
WKQEAEGAIYHLASI	POPDC3	21	Q9HBV1
FYLGKHSGRKLQWQS	CUL4B	711	Q13620
WLVYSGNKHLKIATF	KYAT3	251	Q6YP21
HLGLKSLVDGYKQWS	MAP3K9	636	P80192
EALKHVYLSGINSWK	CPT1B	26	Q92523
KLYGDKWNSFTILLI	FPGT	111	O14772
DQKNGATHYWTLEKL	KIF1A	791	Q12756
TVGALKHLREWYSAK	MTBP	186	Q96DY7
KHLREWYSAKITIAG	MTBP	191	Q96DY7
LIKENLWSSYLTKGV	SLC12A5	376	Q9H2X9
LVHLGYWLNKDKVAI	ITK	376	Q08881
KLQTGWSVHTYQTEK	RPH3AL	26	Q9UNE2
KVDVYLWLGSIKHAS	FER1L6	776	Q2WGJ9
GLWSLYKDKHLVKSA	GALNTL6	26	Q49A17
EKTWNLGLSNAKLSY	IGF2R	686	P11717
KIHKNSSTYWEGKAD	TARS1	276	P26639
RIYHQLKKLGSSLDW	VARS1	426	P26640
SGKHYWEVDVSKKTA	TRIM34	346	Q9BYJ4
TESLLRLEWHIKGKY	THADA	441	Q6YHU6
VVWAKHVAEKNGYLG	SEL1L3	861	Q68CR1
IVSKYRTHHGASLWK	RPL37AP8	11	A6NKH3
ILDDGGDLTHWVYKK	AHCYL1	226	O43865
SDGSWLKLNLHKKYD	IQGAP2	596	Q13576
YLVKEIEKLCGHANW	INSL6	36	Q9Y581
YGTKQWTLIAKHLKG	MYBL2	101	P10244
WYSHSKEKIQNLSLI	HAVCR2	226	Q8TDQ0
LLSDGKWHTVKTDYV	LAMA1	2791	P25391
YKLLASKSESIWVQA	NBEA	751	Q8NFP9
IWVQALKVLGYFLKH	NBEA	761	Q8NFP9
VLASSYDTAWKKHDL	SMG1	3161	Q96Q15
KVLHLVSQWIALYKD	RAPGEF5	146	Q92565
ELGKQYWLITAFHAK	TGFBR2	316	P37173
KLFVTHTVDELLWGY	SCARB2	166	Q14108
VLELWHGVTYAFKDL	THNSL2	101	Q86YJ6
SYSGKQTHEKWQDIL	TAOK3	56	Q9H2K8
KEKEAHAWLQAGKIY	SH3TC1	1066	Q8TE82
LWQKDHLLSVSLSGY	WDR1	286	O75083
KSELGRKWHKASNYI	P2RY14	176	Q15391
KDFLTGYTALHWIAK	SOWAHB	626	A6NEL2
GQIVAALSTAKYKNW	PRG4	1241	Q92954
LFLYILGKKLHQATW	SLC47A1	231	Q96FL8
VLGHQLLKWIIKSNY	SRPK3	166	Q9UPE1
FLKKKWGIGYHLSLQ	ABCA8	701	O94911
HGSAKFYISDLWKVT	ATPSCKMT	136	Q6P4H8
TLTDKWYGESQKLAA	ATAD1	161	Q8NBU5
VWEFKYGDLLGHLKI	CLN5	101	O75503
KTEHIGFVIYSWRKS	CLECL1	21	Q8IZS7
VTAIKQGYEDWLRHK	ATP11A	106	P98196
KKAWTEHQEYGLIID	ATP11C	741	Q8NB49
SGKHYWEVDVSKKTA	TRIM5	356	Q9C035
LSSGKHYWEVDVKDS	TRIM77	336	I1YAP6
LINDSLYDWHVKLQK	UBE2Q2	231	Q8WVN8
SVNWKHKDAAIYLVT	CSE1L	421	P55060
IFKTLHGNIWYEKDG	VPS13A	1331	Q96RL7
WDKSLLKIYSGSSHQ	TMPRSS13	231	Q9BYE2
IWKSGGDLTLHYRQK	WDR48	661	Q8TAF3
YKGAVAQVLWHLFSI	XKR7	296	Q5GH72
AEGYRKLSLKGHNDW	WDR88	351	Q6ZMY6
KSRGVYWHSELQKGL	ZSCAN32	441	Q9NX65
KEAYSHNLWDGARKT	TMEM68	81	Q96MH6
EGLKAHKYSIVIGFW	MRAP2	36	Q96G30
ILGNKALWEHLSYTE	PHLPP2	981	Q6ZVD8
YTVHVWAQKGDRESK	TNN	596	Q9UQP3
VVHWYFKLLDKNSSG	SMOC2	351	Q9H3U7
SVDHGISKDKRDYLW	SYCP1	826	Q15431
GWSTNLNEYKKIHTG	ZNF721	191	Q8TF20
SFGWSTNLNEYKKIH	ZNF721	721	Q8TF20
WQHYLASEKKSLASR	WDFY4	2171	Q6ZS81
LGNWTYKAHVMSSLK	ZNF840P	81	A6NDX5
HAKWEQATKLILNYP	NF1	781	P21359
LESLDYKGHVNWEIL	PRAMEF10	416	O60809
SVLKVWHGAYNSGLL	SLC6A9	56	P48067
WYSTHSLVGDKNIIL	THNSL1	46	Q8IYQ7
AQKAKYHLCSAGWLE	STAB2	2236	Q8WWQ8
QALKVEAKLEHWYIT	VPS13C	571	Q709C8
TWTYAANVGEHDLLK	VPS13C	3021	Q709C8
KGYRQHWVVFKETTL	FERMT3	371	Q86UX7
CAAGKWILTKDYIIH	SLF1	61	Q9BQI6
WILTKDYIIHSAKSG	SLF1	66	Q9BQI6
AKLQQLWLKAHYIEA	SIX2	81	Q9NPC8
APKDNSLYSVLKIWH	ZNF630	106	Q2M218
KTGFSKGIHYWELTV	TRIM9	571	Q9C026
KEQVYSLEHCSALKW	TOPAZ1	1661	Q8N9V7
KGLLIIKAEDHYWGQ	ZSCAN16	11	Q9H4T2
TTHSRKKDWKTLYGA	UCKL1	186	Q9NWZ5
LKYHLLLQELGKHWA	PLEKHG2	241	Q9H7P9
YHAWKANAIGRSAKT	PSMA8	161	Q8TAA3
YHGNKLKGVDLLRSW	TTLL4	1056	Q14679
FHAGCLKKWLYVQET	RNF145	556	Q96MT1
WNIHKSGLKVSEYSL	WDR91	631	A4D1P6
EKYLASVAAGKWVLH	TOPBP1	1316	Q92547
STEWLEGYLSVLHLK	TFR2	486	Q9UP52
ENPSHVQLWLKLAYK	ZFC3H1	1356	O60293
LGEWETYKHSSKLID	USP6	81	P35125
RKDHQKKYGATVDLW	TBK1	191	Q9UHD2
SSGKHYWEVDVAKKT	TRIM6	351	Q9C030
GTSFIWSSYLIQHKK	ZNF606	406	Q8WXB4
WKHFYLSPLDNSKAV	ZBED4	291	O75132
ESHAGKVVLRSWYEK	FAM50B	286	Q9Y247
HGKAIKVSYDEWNRK	AGL	1316	P35573
QWENVHKKVISSGYE	LDHAL6A	226	Q6ZMR3
QLGKDWTHQGIAKLY	LPIN2	706	Q92539
WAQLAIAAHKKGIYA	MYO7A	1431	Q13402
DWKRSIVAYFNKHAG	MYO7A	2076	Q13402
SDNLYKSDLQWLKGI	NEB	2651	P20929