Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionErbB-2 class receptor binding

NRG1 MUC4

3.98e-054522GO:0005176
GeneOntologyMolecularFunctionextracellular matrix constituent, lubricant activity

MUC3A MUC4

3.98e-054522GO:0030197
GeneOntologyMolecularFunctionextracellular matrix structural constituent

COL7A1 MUC3A MUC4 MUC5AC MUC6

1.27e-04188525GO:0005201
GeneOntologyBiologicalProcessstem cell population maintenance

VANGL2 APC BICRAL SAP130 JMJD1C MED12

2.83e-05237526GO:0019827
GeneOntologyBiologicalProcessmaintenance of cell number

VANGL2 APC BICRAL SAP130 JMJD1C MED12

3.18e-05242526GO:0098727
GeneOntologyCellularComponentGolgi lumen

MUC16 MUC5B MUC12 MUC3A MUC4 MUC5AC MUC6

1.09e-08109537GO:0005796
DomainVWD

MUC5B MUC4 MUC5AC MUC6

1.03e-0716534SM00216
DomainVWF_type-D

MUC5B MUC4 MUC5AC MUC6

1.03e-0716534IPR001846
DomainVWFD

MUC5B MUC4 MUC5AC MUC6

1.03e-0716534PS51233
DomainVWD

MUC5B MUC4 MUC5AC MUC6

1.03e-0716534PF00094
DomainNXPH/NXPE

NXPE4 NXPE1 NXPE2

1.20e-068533IPR026845
DomainNeurexophilin

NXPE4 NXPE1 NXPE2

1.20e-068533PF06312
DomainTIL

MUC5B MUC5AC MUC6

4.66e-0612533PF01826
DomainC8

MUC5B MUC5AC MUC6

4.66e-0612533PF08742
DomainUnchr_dom_Cys-rich

MUC5B MUC5AC MUC6

6.05e-0613533IPR014853
DomainC8

MUC5B MUC5AC MUC6

6.05e-0613533SM00832
DomainTIL_dom

MUC5B MUC5AC MUC6

7.68e-0614533IPR002919
DomainVWC_out

MUC5B MUC5AC MUC6

2.02e-0519533SM00215
DomainCT

MUC5B MUC5AC MUC6

3.20e-0522533SM00041
DomainSEA

MUC16 MUC12 MUC3A

3.67e-0523533PS50024
DomainSEA_dom

MUC16 MUC12 MUC3A

3.67e-0523533IPR000082
DomainPINIT

PIAS2 PIAS1

4.72e-054532IPR023321
DomainPINIT

PIAS2 PIAS1

4.72e-054532PS51466
DomainPINIT

PIAS2 PIAS1

4.72e-054532PF14324
DomainCys_knot_C

MUC5B MUC5AC MUC6

4.75e-0525533IPR006207
DomainCTCK_2

MUC5B MUC5AC MUC6

4.75e-0525533PS01225
DomainWxxW_domain

MUC5B MUC5AC

1.18e-046532IPR025155
DomainMucin2_WxxW

MUC5B MUC5AC

1.18e-046532PF13330
Domainzf-MIZ

PIAS2 PIAS1

1.64e-047532PF02891
DomainZF_SP_RING

PIAS2 PIAS1

1.64e-047532PS51044
DomainZnf_MIZ

PIAS2 PIAS1

2.19e-048532IPR004181
DomainVWF_dom

MUC5B MUC5AC MUC6

2.29e-0442533IPR001007
DomainSEA

MUC16 MUC3A

7.03e-0414532SM00200
DomainGlyco_hormone_CN

MUC5B MUC5AC

8.10e-0415532IPR006208
DomainCys_knot

MUC5B MUC5AC

8.10e-0415532PF00007
DomainCTCK_1

MUC5B MUC5AC

1.17e-0318532PS01185
Domain-

PIAS2 PIAS1

1.60e-03215321.10.720.30
DomainSEA

MUC16 MUC12

1.76e-0322532PF01390
DomainSAP

PIAS2 PIAS1

1.76e-0322532PF02037
DomainSAP

PIAS2 PIAS1

1.92e-0323532SM00513
DomainSAP

PIAS2 PIAS1

2.27e-0325532PS50800
DomainSAP_dom

PIAS2 PIAS1

2.27e-0325532IPR003034
DomainVWC

MUC5B MUC5AC

2.85e-0328532PF00093
DomainIg_E-set

NXPE4 NXPE1 NXPE2

3.21e-03104533IPR014756
DomainSAM/pointed

ANKS6 SHANK2 MAP3K5

4.47e-03117533IPR013761
DomainVWFC_1

MUC5B MUC5AC

4.68e-0336532PS01208
DomainVWC

MUC5B MUC5AC

5.20e-0338532SM00214
DomainVWFC_2

MUC5B MUC5AC

5.20e-0338532PS50184
PathwayREACTOME_DEFECTIVE_GALNT3_CAUSES_HFTC

MUC16 MUC5B MUC12 MUC3A MUC4 MUC5AC MUC6

3.46e-1516357M27410
PathwayREACTOME_DEFECTIVE_C1GALT1C1_CAUSES_TNPS

MUC16 MUC5B MUC12 MUC3A MUC4 MUC5AC MUC6

5.86e-1517357M27412
PathwayREACTOME_TERMINATION_OF_O_GLYCAN_BIOSYNTHESIS

MUC16 MUC5B MUC12 MUC3A MUC4 MUC5AC MUC6

7.31e-1423357M556
PathwayREACTOME_DECTIN_2_FAMILY

MUC16 MUC5B MUC12 MUC3A MUC4 MUC5AC MUC6

1.95e-1326357M27483
PathwayREACTOME_O_LINKED_GLYCOSYLATION_OF_MUCINS

MUC16 MUC5B MUC12 MUC3A MUC4 MUC5AC MUC6

1.37e-1062357M546
PathwayREACTOME_DISEASES_ASSOCIATED_WITH_O_GLYCOSYLATION_OF_PROTEINS

MUC16 MUC5B MUC12 MUC3A MUC4 MUC5AC MUC6

2.67e-1068357M27303
PathwayREACTOME_TERMINATION_OF_O_GLYCAN_BIOSYNTHESIS

MUC16 MUC5B MUC4 MUC5AC MUC6

1.39e-0921355MM15706
PathwayREACTOME_O_LINKED_GLYCOSYLATION

MUC16 MUC5B MUC12 MUC3A MUC4 MUC5AC MUC6

8.69e-09111357M27416
PathwayREACTOME_C_TYPE_LECTIN_RECEPTORS_CLRS

MUC16 MUC5B MUC12 MUC3A MUC4 MUC5AC MUC6

4.37e-08140357M27484
PathwayREACTOME_DISEASES_OF_GLYCOSYLATION

MUC16 MUC5B MUC12 MUC3A MUC4 MUC5AC MUC6

5.06e-08143357M27275
PathwayREACTOME_O_LINKED_GLYCOSYLATION_OF_MUCINS

MUC16 MUC5B MUC4 MUC5AC MUC6

3.47e-0760355MM15636
PathwayREACTOME_DISEASES_OF_METABOLISM

MUC16 MUC5B MUC12 MUC3A MUC4 MUC5AC MUC6

2.23e-06250357M27554
PathwayREACTOME_POST_TRANSLATIONAL_PROTEIN_MODIFICATION

COL7A1 APC MUC16 MUC5B MUC12 MBD5 PIAS2 MUC3A MUC4 MUC5AC PIAS1 MUC6 NUP153 FBXW7

4.92e-0614753514M19806
PathwayREACTOME_O_LINKED_GLYCOSYLATION

MUC16 MUC5B MUC4 MUC5AC MUC6

6.80e-06109355MM15164
PathwayREACTOME_POST_TRANSLATIONAL_PROTEIN_MODIFICATION

COL7A1 APC MUC16 MUC5B MBD5 PIAS2 MUC4 MUC5AC PIAS1 MUC6 NUP153 FBXW7

7.71e-0513893512MM15307
PathwayREACTOME_SUMOYLATION_OF_UBIQUITINYLATION_PROTEINS

PIAS2 PIAS1 NUP153

1.21e-0439353M27238
PathwayREACTOME_SUMOYLATION_OF_UBIQUITINYLATION_PROTEINS

PIAS2 PIAS1 NUP153

2.11e-0447353MM14939
PathwayBIOCARTA_RANBP2_PATHWAY

PIAS2 PIAS1

3.25e-0411352M22027
PathwayPID_RANBP2_PATHWAY

PIAS2 PIAS1

3.25e-0411352M140
PathwayREACTOME_SUMOYLATION_OF_CHROMATIN_ORGANIZATION_PROTEINS

PIAS2 PIAS1 NUP153

5.51e-0465353MM15147
PathwayREACTOME_SUMOYLATION_OF_TRANSCRIPTION_FACTORS

PIAS2 PIAS1

7.03e-0416352MM14938
PathwayREACTOME_SUMOYLATION_OF_CHROMATIN_ORGANIZATION_PROTEINS

PIAS2 PIAS1 NUP153

7.14e-0471353M27394
PathwayBIOCARTA_RANBP2_PATHWAY

PIAS2 PIAS1

8.94e-0418352MM1549
PathwayBIOCARTA_41BB_PATHWAY

ATF2 MAP3K5

8.94e-0418352M2064
PathwayBIOCARTA_41BB_PATHWAY

ATF2 MAP3K5

8.94e-0418352MM1511
PathwayREACTOME_SUMOYLATION_OF_DNA_DAMAGE_RESPONSE_AND_REPAIR_PROTEINS

PIAS2 PIAS1 NUP153

9.04e-0477353M27226
PathwayREACTOME_SUMOYLATION_OF_TRANSCRIPTION_FACTORS

PIAS2 PIAS1

1.11e-0320352M27237
PathwayREACTOME_SUMOYLATION_OF_DNA_DAMAGE_RESPONSE_AND_REPAIR_PROTEINS

PIAS2 PIAS1 NUP153

1.16e-0384353MM14929
PathwayREACTOME_SUMOYLATION_OF_INTRACELLULAR_RECEPTORS

PIAS2 PIAS1

2.17e-0328352MM15042
Pubmed

Mucin gene expression in human laryngeal epithelia: effect of laryngopharyngeal reflux.

MUC16 MUC5B MUC12 MUC3A MUC4 MUC5AC MUC6

3.97e-161853718834073
Pubmed

Expression of Muc19/Smgc gene products during murine sublingual gland development: cytodifferentiation and maturation of salivary mucous cells.

MUC16 MUC5B MUC5AC MUC6

7.19e-11653419110483
Pubmed

A human MAP kinase interactome.

NAV3 APC NAV2 BICRAL MUC12 MBD5 PIAS2 PIAS1 NUP153 MAP3K5

2.95e-09486531020936779
Pubmed

Regulation of neuregulin 1beta1-induced MUC5AC and MUC5B expression in human airway epithelium.

NRG1 MUC5B MUC5AC

3.34e-09353319556605
Pubmed

Epigenetic regulation (DNA methylation, histone modifications) of the 11p15 mucin genes (MUC2, MUC5AC, MUC5B, MUC6) in epithelial cancer cells.

MUC5B MUC5AC MUC6

1.34e-08453317471237
Pubmed

The mouse secreted gel-forming mucin gene cluster.

MUC5B MUC5AC MUC6

1.34e-08453314984930
Pubmed

Effects of the Helicobacter pylori Virulence Factor CagA and Ammonium Ion on Mucins in AGS Cells.

MUC5B MUC5AC MUC6

1.34e-08453329869461
Pubmed

Expression of MUC2, MUC5AC, MUC5B, and MUC6 mucins in colorectal cancers and their association with the CpG island methylator phenotype.

MUC5B MUC5AC MUC6

1.34e-08453323807779
Pubmed

Characterization of mouse muc6 and evidence of conservation of the gel-forming mucin gene cluster between human and mouse.

MUC5B MUC5AC MUC6

1.34e-08453312676567
Pubmed

Polymorphism of human mucin genes in chest disease: possible significance of MUC2.

MUC5B MUC4 MUC5AC

3.33e-08553311062147
Pubmed

MUC1, MUC2, MUC4, MUC5AC and MUC6 expression in the progression of prostate cancer.

MUC4 MUC5AC MUC6

3.33e-08553316475027
Pubmed

Shotgun sequencing of the human transcriptome with ORF expressed sequence tags.

COL7A1 UBAP2 SHANK2 DCLRE1C PDE4DIP EPC1 NAV2 MUC16 MUC3A

1.43e-0755253910737800
Pubmed

Cloning and analysis of cDNA encoding a major airway glycoprotein, human tracheobronchial mucin (MUC5).

MUC5B MUC5AC

2.28e-0625327513696
Pubmed

Airway mucin MUC5AC and MUC5B concentrations and the initiation and progression of chronic obstructive pulmonary disease: an analysis of the SPIROMICS cohort.

MUC5B MUC5AC

2.28e-06253234058148
Pubmed

The association between MUC5AC and MUC5B genes expression and remodeling progression in severe neutrophilic asthma: A direct relationship.

MUC5B MUC5AC

2.28e-06253237146737
Pubmed

MUC5AC and MUC5B Mucins Are Decreased in Cystic Fibrosis Airway Secretions.

MUC5B MUC5AC

2.28e-06253214988081
Pubmed

Mucin glycosylation changes in cystic fibrosis lung disease are not manifest in submucosal gland secretions.

MUC5B MUC5AC

2.28e-06253215563276
Pubmed

Alterations of the ocular surface epithelial MUC16 and goblet cell MUC5AC in patients with atopic keratoconjunctivitis.

MUC16 MUC5AC

2.28e-06253218782111
Pubmed

The expression of MUC5AC and MUC5B mucin genes in the mucosa of chronic rhinosinusitis and nasal polyposis.

MUC5B MUC5AC

2.28e-06253217621824
Pubmed

MUC4 and MUC5AC are highly specific tumour-associated mucins in biliary tract cancer.

MUC4 MUC5AC

2.28e-06253218475301
Pubmed

Enhanced discrimination of malignant from benign pancreatic disease by measuring the CA 19-9 antigen on specific protein carriers.

MUC16 MUC5AC

2.28e-06253222220206
Pubmed

Muc5b is required for airway defence.

MUC5B MUC5AC

2.28e-06253224317696
Pubmed

Macrophages are related to goblet cell hyperplasia and induce MUC5B but not MUC5AC in human bronchus epithelial cells.

MUC5B MUC5AC

2.28e-06253222391959
Pubmed

C-Mannosylation of MUC5AC and MUC5B Cys subdomains.

MUC5B MUC5AC

2.28e-06253214718370
Pubmed

Mucins MUC5AC and MUC5B Are Variably Packaged in the Same and in Separate Secretory Granules.

MUC5B MUC5AC

2.28e-06253235776514
Pubmed

The ocular surface phenotype of Muc5ac and Muc5b null mice.

MUC5B MUC5AC

2.28e-06253224327612
Pubmed

Mucin production during prenatal and postnatal murine lung development.

MUC5B MUC5AC

2.28e-06253221653907
Pubmed

Clinicopathological features of superficial non-ampurally duodenal epithelial tumor; gastric phenotype of histology correlates to higher malignant potency.

MUC5AC MUC6

2.28e-06253228321513
Pubmed

Human mucin genes MUC2, MUC3, MUC4, MUC5AC, MUC5B, and MUC6 express stable and extremely large mRNAs and exhibit a variable length polymorphism. An improved method to analyze large mRNAs.

MUC5AC MUC6

2.28e-0625329422745
Pubmed

MUC5B mobilizes and MUC5AC spatially aligns mucociliary transport on human airway epithelium.

MUC5B MUC5AC

2.28e-06253236427316
Pubmed

Gel-forming mucins form distinct morphologic structures in airways.

MUC5B MUC5AC

2.28e-06253228607090
Pubmed

Aberrant expression of MUC5AC and MUC6 gastric mucins and sialyl Tn antigen in intraepithelial neoplasms of the pancreas.

MUC5AC MUC6

2.28e-06253212360467
Pubmed

Mucin deficiency causes functional and structural changes of the ocular surface.

MUC5B MUC5AC

2.28e-06253223272068
Pubmed

Depletion of transmembrane mucin 4 (Muc4) alters intestinal homeostasis in a genetically engineered mouse model of colorectal cancer.

APC MUC4

2.28e-06253235255004
Pubmed

Muc5b is mainly expressed and sialylated in the nasal olfactory epithelium whereas Muc5ac is exclusively expressed and fucosylated in the nasal respiratory epithelium.

MUC5B MUC5AC

2.28e-06253231030254
Pubmed

Younger patients with COME are more likely to have mucoid middle ear fluid containing mucin MUC5B.

MUC5B MUC5AC

2.28e-06253227729120
Pubmed

FBXW7 influences murine intestinal homeostasis and cancer, targeting Notch, Jun, and DEK for degradation.

APC FBXW7

2.28e-06253221282377
Pubmed

The idiopathic pulmonary fibrosis honeycomb cyst contains a mucocilary pseudostratified epithelium.

MUC5B MUC5AC

2.28e-06253223527003
Pubmed

Up-regulation of MUC5AC and MUC5B mucin genes in nasopharyngeal respiratory mucosa and selective up-regulation of MUC5B in middle ear in pediatric otitis media with effusion.

MUC5B MUC5AC

2.28e-06253216540890
Pubmed

The investigation of relevancy between PIAS1 and PIAS2 gene expression and disease severity of multiple sclerosis.

PIAS2 PIAS1

2.28e-06253231084243
Pubmed

De novo NUF2 variant in a novel inherited bone marrow failure syndrome including microcephaly and renal hypoplasia.

MUC5B MUC5AC

2.28e-06253236111525
Pubmed

Neurexophilin and PC-esterase domain family member 4 (NXPE4) and prostate androgen-regulated mucin-like protein 1 (PARM1) as prognostic biomarkers for colorectal cancer.

NXPE4 PARM1

2.28e-06253231297877
Pubmed

Abnormalities in MUC5AC and MUC5B Protein in Airway Mucus in Asthma.

MUC5B MUC5AC

2.28e-06253227845589
Pubmed

Contribution of mucus concentration and secreted mucins Muc5ac and Muc5b to the pathogenesis of muco-obstructive lung disease.

MUC5B MUC5AC

2.28e-06253227435107
Pubmed

Immunocytochemistry for MUC4 and MUC16 is a useful adjunct in the diagnosis of pancreatic adenocarcinoma on fine-needle aspiration cytology.

MUC16 MUC4

2.28e-06253223544943
Pubmed

Mucins MUC5B and MUC5AC in Distal Airways and Honeycomb Spaces: Comparison among Idiopathic Pulmonary Fibrosis/Usual Interstitial Pneumonia, Fibrotic Nonspecific Interstitial Pneumonitis, and Control Lungs.

MUC5B MUC5AC

2.28e-06253226871672
Pubmed

Gastric MUC5AC and MUC6 are large oligomeric mucins that differ in size, glycosylation and tissue distribution.

MUC5AC MUC6

2.28e-06253211988092
Pubmed

Expression of mucins in mucoid otitis media.

MUC5B MUC4

2.28e-06253214690056
Pubmed

Expression of PIAS Genes in Migraine Patients.

PIAS2 PIAS1

2.28e-06253233763841
Pubmed

Investigation of the atypical FBXW7 mutation spectrum in human tumours by conditional expression of a heterozygous propellor tip missense allele in the mouse intestines.

APC FBXW7

2.28e-06253223676439
Pubmed

Normal murine respiratory tract has its mucus concentrated in clouds based on the Muc5b mucin.

MUC5B MUC5AC

2.28e-06253232348677
Pubmed

In silico cloning of mouse Muc5b gene and upregulation of its expression in mouse asthma model.

MUC5B MUC5AC

2.28e-06253211587997
Pubmed

Immunohistochemical expression profiles of mucin antigens in salivary gland mucoepidermoid carcinoma: MUC4- and MUC6-negative expression predicts a shortened survival in the early postoperative phase.

MUC4 MUC6

2.28e-06253228649694
Pubmed

Alteration of ocular surface mucins in MUC5AC-DTA transgenic mice.

MUC4 MUC5AC

2.28e-06253219158956
Pubmed

Pathobiological implications of mucin (MUC) expression in the outcome of small bowel cancer.

MUC16 MUC5AC

2.28e-06253224722639
Pubmed

Reassessment of the importance of mucins in determining sputum properties in cystic fibrosis.

MUC5B MUC5AC

2.28e-06253224332705
Pubmed

Pathophysiological relevance of sputum MUC5AC and MUC5B levels in patients with mild asthma.

MUC5B MUC5AC

2.28e-06253234656442
Pubmed

RNF43 inhibits WNT5A-driven signaling and suppresses melanoma invasion and resistance to the targeted therapy.

VANGL2 APC TMEM131 FAM171B JMJD1C NUP153

3.01e-0626353634702444
Pubmed

Proximity-dependent Mapping of the Androgen Receptor Identifies Kruppel-like Factor 4 as a Functional Partner.

EPC1 UBN2 ATF2 SAP130 JMJD1C MED12

3.35e-0626853633640491
Pubmed

The in vivo Interaction Landscape of Histones H3.1 and H3.3.

FSIP2 ZNF146 MLLT6 UBN2 PIAS2 FOXJ3 PIAS1 JMJD1C

3.70e-0660853836089195
Pubmed

PRISMA and BioID disclose a motifs-based interactome of the intrinsically disordered transcription factor C/EBPα.

MLLT6 BICRAL UBN2 FOXJ3 ATF2 PIAS1 SAP130 JMJD1C MED12 NUP153

5.58e-061103531034189442
Pubmed

Aberrant expression of mucin core proteins and o-linked glycans associated with progression of pancreatic cancer.

MUC4 MUC6

6.83e-06353223446997
Pubmed

Assessment of mucin-related gene alterations following treatment with rebamipide ophthalmic suspension in Sjögren's syndrome-associated dry eyes.

MUC16 MUC5AC

6.83e-06353233232357
Pubmed

Interleukin-33 induces mucin gene expression and goblet cell hyperplasia in human nasal epithelial cells.

MUC5B MUC5AC

6.83e-06353227776277
Pubmed

Microbial products alter the expression of membrane-associated mucin and antimicrobial peptides in a three-dimensional human endocervical epithelial cell model.

MUC16 MUC4

6.83e-06353223053434
Pubmed

Secretory carcinoma of breast: pattern of MUC 2/MUC 4/MUC 6 expression.

MUC4 MUC6

6.83e-06353223305535
Pubmed

High-Mobility Group Box 1 Upregulates MUC5AC and MUC5B Expression in Primary Airway Epithelial Cells.

MUC5B MUC5AC

6.83e-06353229286856
Pubmed

DUSP28 links regulation of Mucin 5B and Mucin 16 to migration and survival of AsPC-1 human pancreatic cancer cells.

MUC16 MUC5B

6.83e-06353227230679
Pubmed

Integrative analysis of the cancer genome atlas and cancer cell lines encyclopedia large-scale genomic databases: MUC4/MUC16/MUC20 signature is associated with poor survival in human carcinomas.

MUC16 MUC4

6.83e-06353230236127
Pubmed

Mucin expression in reactive gastropathy: an immunohistochemical analysis.

MUC5AC MUC6

6.83e-06353217227128
Pubmed

Nebulized Menthol Impairs Mucociliary Clearance via TRPM8 and MUC5AC/MUC5B in Primary Airway Epithelial Cells.

MUC5B MUC5AC

6.83e-06353236675209
Pubmed

Expression of mucin 3 and mucin 5AC in arthritic synovial tissue.

MUC3A MUC5AC

6.83e-06353218163520
Pubmed

Mucin phenotype expression of gastric neuroendocrine neoplasms: analysis of histopathology and carcinogenesis.

MUC5AC MUC6

6.83e-06353223828549
Pubmed

Regulation of membrane-associated mucins in the human corneal epithelial cells by dexamethasone.

MUC16 MUC4

6.83e-06353217592322
Pubmed

Th2 cytokines orchestrate the secretion of MUC5AC and MUC5B in IL-5-positive chronic rhinosinusitis with nasal polyps.

MUC5B MUC5AC

6.83e-06353229802623
Pubmed

Differential Expression of MUC12, MUC16, and MUC20 in Patients with Active and Remission Ulcerative Colitis.

MUC16 MUC12

6.83e-06353226770020
Pubmed

Cadherin-catenin adhesion system and mucin expression: a comparison between young and older patients with gastric carcinoma.

MUC5AC MUC6

6.83e-06353218825309
Pubmed

Neuron navigator: a human gene family with homology to unc-53, a cell guidance gene from Caenorhabditis elegans.

NAV3 NAV2

6.83e-06353212079279
Pubmed

Sensory deficits in mice hypomorphic for a mammalian homologue of unc-53.

NAV3 NAV2

6.83e-06353215158073
Pubmed

Adenomatous and foveolar gastric dysplasia: distinct patterns of mucin expression and background intestinal metaplasia.

MUC5AC MUC6

6.83e-06353218300795
Pubmed

Autophagy of mucin granules contributes to resolution of airway mucous metaplasia.

MUC5B MUC5AC

6.83e-06353234158522
Pubmed

A comprehensive analysis of common genetic variation in MUC1, MUC5AC, MUC6 genes and risk of stomach cancer.

MUC5AC MUC6

6.83e-06353219924550
Pubmed

Resistin upregulates MUC5AC/B mucin gene expression in human airway epithelial cells.

MUC5B MUC5AC

6.83e-06353229604272
Pubmed

PIAS genes as disease markers in bipolar disorder.

PIAS2 PIAS1

6.83e-06353230861611
Pubmed

F-box and WD repeat domain-containing 7 regulates intestinal cell lineage commitment and is a haploinsufficient tumor suppressor.

APC FBXW7

6.83e-06353220638938
Pubmed

IL-8 regulates mucin gene expression at the posttranscriptional level in lung epithelial cells.

MUC5B MUC5AC

6.83e-06353219596978
Pubmed

Pore membrane and/or filament interacting like protein 1 (POMFIL1) is predominantly expressed in the nervous system and encodes different protein isoforms.

NAV3 NAV2

6.83e-06353212062803
Pubmed

Genome-wide bidirectional CRISPR screens identify mucins as host factors modulating SARS-CoV-2 infection.

MUC16 MUC4

6.83e-06353235879412
Pubmed

Clinicopathological and prognostic significance of MUC-2, MUC-4 and MUC-5AC expression in japanese gastric carcinomas.

MUC4 MUC5AC

6.83e-06353223464473
Pubmed

Aquaporin 5 expression increases mucin production in lung adenocarcinoma.

MUC5B MUC5AC

6.83e-06353221455588
Pubmed

A testis-specific androgen receptor coregulator that belongs to a novel family of nuclear proteins.

PIAS2 ATF2

6.83e-0635329920921
Pubmed

Expression of leptin receptor in nasal polyps: leptin as a mucosecretagogue.

MUC5B MUC5AC

6.83e-06353220422702
Pubmed

PIAS proteins modulate transcription factors by functioning as SUMO-1 ligases.

PIAS2 PIAS1

6.83e-06353212077349
Pubmed

Functional Consequences of Differential O-glycosylation of MUC1, MUC4, and MUC16 (Downstream Effects on Signaling).

MUC16 MUC4

6.83e-06353227483328
Pubmed

MicroRNA-200c modulates the expression of MUC4 and MUC16 by directly targeting their coding sequences in human pancreatic cancer.

MUC16 MUC4

6.83e-06353224204560
Pubmed

Expression of the transmembrane mucins, MUC1, MUC4 and MUC16, in normal endometrium and in endometriosis.

MUC16 MUC4

6.83e-06353224939955
Pubmed

Mucin gene polymorphisms in otitis media patients.

MUC5B MUC5AC

6.83e-06353219718741
Pubmed

An inducible CRISPR/Cas9 screen identifies DTX2 as a transcriptional regulator of human telomerase.

DSG2 PIAS2 PIAS1 JMJD1C NUP153

8.24e-0618053535198878
Pubmed

Impaired OTUD7A-dependent Ankyrin regulation mediates neuronal dysfunction in mouse and human models of the 15q13.3 microdeletion syndrome.

VANGL2 SHANK2 PDE4DIP LRRC4C FAM171B

1.28e-0519753536604605
Pubmed

The transactivating function of peroxisome proliferator-activated receptor gamma is negatively regulated by SUMO conjugation in the amino-terminal domain.

PIAS2 PIAS1

1.36e-05453215507114
InteractionNAV2 interactions

NAV3 APC NAV2 PIAS2

4.51e-0643524int:NAV2
InteractionKLF3 interactions

EPC1 UBN2 PIAS2 PIAS1 SAP130 JMJD1C

2.59e-05228526int:KLF3
InteractionPKP3 interactions

DSG2 PDE4DIP PIAS1 MED12 FBXW7

2.62e-05136525int:PKP3
Cytoband11q23.2

NXPE4 NXPE1

1.98e-041853211q23.2
Cytoband11p15.5

MUC5B MUC5AC MUC6

3.53e-0411853311p15.5
Cytoband2q32.1

FSIP2 FAM171B

5.57e-04305322q32.1
Cytoband7q22

MUC12 MUC3A

8.95e-04385327q22
CytobandEnsembl 112 genes in cytogenetic band chr11q23

NXPE4 NXPE1 NXPE2

2.13e-03220533chr11q23
CytobandEnsembl 112 genes in cytogenetic band chr11p15

NAV2 MUC5B MUC5AC MUC6

4.10e-03564534chr11p15
GeneFamilyCD molecules|Mucins

MUC16 MUC5B MUC12 MUC3A MUC4 MUC5AC MUC6

1.86e-1521307648
GeneFamilyZinc fingers MIZ-type

PIAS2 PIAS1

5.56e-05730285
CoexpressionNABA_ECM_AFFILIATED

MUC16 MUC5B MUC12 MUC3A MUC4 MUC5AC MUC6 PARM1

1.83e-09170538M5880
CoexpressionNABA_ECM_AFFILIATED

MUC16 MUC5B MUC4 MUC5AC MUC6 PARM1

7.92e-07158536MM17063
CoexpressionDAZARD_RESPONSE_TO_UV_NHEK_DN

ZNF146 NAV3 BICRAL FOXJ3 ATF2 NUP153 MAP3K5

2.36e-06300537M8702
CoexpressionNABA_MATRISOME_ASSOCIATED

NRG1 MUC16 MUC5B MUC12 MUC3A MUC4 MUC5AC MUC6 PARM1

1.78e-05751539M5885
CoexpressionNABA_MATRISOME

NRG1 COL7A1 MUC16 MUC5B MUC12 MUC3A MUC4 MUC5AC MUC6 PARM1

3.41e-0510265310M5889
CoexpressionGSE23114_PERITONEAL_CAVITY_B1A_BCELL_VS_SPLEEN_BCELL_IN_SLE2C1_MOUSE_DN

UBAP2 BICRAL MBD5 FOXJ3 MAP3K5

4.43e-05193535M8288
CoexpressionDACOSTA_UV_RESPONSE_VIA_ERCC3_DN

PJA2 NRG1 NAV3 APC TMEM131 BICRAL FOXJ3 ATF2 NUP153

4.94e-05856539M4500
CoexpressionGSE12392_WT_VS_IFNB_KO_CD8A_NEG_SPLEEN_DC_DN

NXPE4 PDE4DIP BICRAL JMJD1C MAP3K5

5.24e-05200535M7150
CoexpressionGSE37532_VISCERAL_ADIPOSE_TISSUE_VS_LN_DERIVED_PPARG_KO_TCONV_CD4_TCELL_DN

FSIP2 NAV2 NXPE1 CACHD1

5.90e-05104534M8938
CoexpressionDAZARD_RESPONSE_TO_UV_SCC_DN

ZNF146 NAV3 FOXJ3 NUP153

8.72e-05115534M7484
ToppCell5'-Adult-LargeIntestine|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

FSIP2 NXPE4 NXPE1 MUC5B MUC12 MUC4 PARM1

3.36e-09195537600174e35574fe7c44dd923adcf43686e7b01e39
ToppCellAT2_cells-IPF_03|World / lung cells shred on cell class, cell subclass, sample id

DSG2 NAV2 MUC5B CACHD1 MUC3A MUC4 PARM1

3.60e-091975375e0d222872a25bb9e9069d3dffda2844bb69874a
ToppCell(5)_Glands_mucous|World / Oesophagus cell shreds on cell class (v1) and cell subclass (v1)

NXPE4 MUC16 MUC5B NXPE2 MUC5AC PARM1

6.93e-08178536f0f19b0d78f2cc5df4d4c321a953a6e447d5114a
ToppCellnucseq-Epithelial-Epithelial_Glandular|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

MUC16 MUC5B MUC3A MUC4 MUC5AC MGAM2

7.17e-08179536859cd8ee414ad6207c046ada2e655e49322dd01c
ToppCell(5)_Epithelial_cells-(5)_Glands_mucous|(5)_Epithelial_cells / Oesophagus cell shreds on cell class (v1) and cell subclass (v1)

NXPE4 MUC16 MUC5B NXPE2 MUC5AC PARM1

7.41e-08180536a4118adaf4b09e2ca01b662ed60e7bbf32a24d58
ToppCellnucseq-Epithelial-Epithelial_Glandular-Goblet|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

MUC16 MUC5B MUC3A MUC4 MUC5AC MGAM2

7.41e-081805363dc80bc636bf0e6ffc9762853132a9fe59fd1f66
ToppCellnucseq-Epithelial-Epithelial_Glandular-Goblet-Goblet|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

MUC16 MUC5B MUC3A MUC4 MUC5AC MGAM2

7.41e-08180536668a2d8e1d5a390309d5eb62c836f5903144bea9
ToppCellControl-Epithelial_cells-Airway_mucous|Control / group, cell type (main and fine annotations)

MUC16 MUC5B MUC3A MUC4 MUC5AC MGAM2

8.17e-0818353615d24a4fb1ffe6cbafbd54fcd7dde9ddcfbe03b2
ToppCellControl-Epithelial_cells-Airway_goblet|Control / group, cell type (main and fine annotations)

MUC16 MUC5B MUC3A MUC4 MUC5AC MGAM2

8.44e-08184536d92a71441e4e19f8c301999d8186f8e48e3cd162
ToppCell5'-GW_trimst-2-LargeIntestine|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

NXPE4 NXPE1 MUC5B MUC12 NXPE2 PARM1

1.19e-071955361a4a5623fa0318ef388cc228c7060e0586a7acf9
ToppCell5'-Adult-LargeIntestine-Epithelial-epithelial_progenitor_cell|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

DSG2 NXPE4 NXPE1 MUC5B MUC12 MUC4

1.30e-0719853608982f9e37591261975ddff9b9a6a59ba836fc0f
ToppCell3'-Adult|3' / Celltypes from developing, pediatric, Crohn's, & adult GI tract

DSG2 NXPE4 NXPE1 MUC5B MUC12 MUC4

1.30e-07198536302adb42089ff22fffc4f01af572ca2e151f7ce7
ToppCell5'-Adult-LargeIntestine-Epithelial-epithelial_progenitor_cell-TA|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

DSG2 NXPE4 NXPE1 MUC5B MUC12 MUC4

1.30e-0719853645a1287dc618a37949978b297e2b782ea80a7f39
ToppCell5'-Adult-LargeIntestine-Epithelial|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

DSG2 NXPE4 NXPE1 MUC5B MUC12 MUC4

1.34e-07199536156354b799346d441dde42dbba09d7bde89ad460
ToppCell3'-GW_trimst-1.5-LargeIntestine-Epithelial-goblet|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

NXPE4 NXPE1 MUC5B NXPE2 MUC4

1.80e-061705359bea81031cdfe45e8cddac3a3afd9ca6c331c45a
ToppCell3'-GW_trimst-1.5-LargeIntestine-Epithelial-goblet-Goblet_cell|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

NXPE4 NXPE1 MUC5B NXPE2 MUC4

1.80e-061705352c5a1469e5743870e96e6c2cc92f0c5096b79f51
ToppCellAT1-AT2_cells-Cryobiopsy_01|World / lung cells shred on cell class, cell subclass, sample id

FSIP2 DSG2 MUC5B MUC5AC MUC6

1.91e-061725350be41df5d35d818deb7316ac21c9366eb4b7bfd1
ToppCell3'-Broncho-tracheal-Epithelial-Epithelial_transtional-secretory-nasal_mucosa_goblet_cell-Goblet_(nasal)-Goblet_(nasal)_L.0.2.2.2|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

COL7A1 MUC16 MUC3A MUC4 SPRED3

2.02e-06174535207aa0118633cbe9a65839bbb1bb3ba9f8118ad2
ToppCellControl-Epithelial_cells-Airway_club|Control / group, cell type (main and fine annotations)

SHANK2 NAV2 CACHD1 MUC4 PARM1

2.45e-06181535c755d23dd9aabc717dc73e2b3fa99a1f751e6507
ToppCellChildren_(3_yrs)-Epithelial-lung_goblet_cell|Children_(3_yrs) / Lineage, Cell type, age group and donor

SHANK2 MUC16 MUC5B MUC4 MUC5AC

2.51e-061825353f1a666fe27dd7529c114539ed5f6b8ca585c875
ToppCellEpithelial-lung_goblet_cell|World / Lineage, Cell type, age group and donor

SHANK2 MUC16 MUC5B MUC4 MUC5AC

2.58e-06183535940cbe298e9c53b5622af09264586ed823d3141f
ToppCell3'-Broncho-tracheal-Epithelial-Epithelial_transtional-secretory-bronchial_goblet_cell-Goblet_(bronchial)-Goblet_(bronchial)_L.0.4.2.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

MUC16 MUC5B MUC4 MUC5AC MUC6

2.65e-0618453501c19a830348ab0b9c02c1546a439de70ee10f97
ToppCellCOVID-19-Epithelial_cells-Airway_club|COVID-19 / group, cell type (main and fine annotations)

SHANK2 NAV2 CACHD1 MUC4 PARM1

2.72e-06185535cfe6fd73d817e173fe803bc1683c291d9bcb8608
ToppCellCOVID-19-Epithelial_cells-Airway_basal|COVID-19 / group, cell type (main and fine annotations)

NRG1 COL7A1 SHANK2 CACHD1 MUC4

2.87e-061875358407a82e98f56a94ea26562bcb6bbe00a8f41661
ToppCellCOVID-19-lung-Secretory|lung / Disease (COVID-19 only), tissue and cell type

SHANK2 MUC5B CACHD1 MUC4 MUC5AC

3.02e-0618953584d48e3ed25bebb8bb8074b3a2c5e2e88cff7f25
ToppCellCOVID-19-Epithelial_cells-Airway_goblet|COVID-19 / group, cell type (main and fine annotations)

SHANK2 MUC16 MUC5B MUC4 MUC5AC

3.10e-0619053551ca9ef4df3220487152fcf684147730637c7cc1
ToppCell3'-Broncho-tracheal-Epithelial-Epithelial_transtional-secretory-bronchial_goblet_cell|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

MUC16 MUC5B MUC4 MUC5AC MUC6

3.10e-061905353c337374d89e69cc0a78e65a4a7e21db7b050fcd
ToppCell3'-Broncho-tracheal-Epithelial-Epithelial_transtional-secretory-bronchial_goblet_cell-Goblet_(bronchial)|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

MUC16 MUC5B MUC4 MUC5AC MUC6

3.10e-0619053523f2ac4da431211084bb6ab0494c2e0b69547cb6
ToppCellCOVID-19-lung-Secretory|COVID-19 / Disease (COVID-19 only), tissue and cell type

SHANK2 MUC5B CACHD1 MUC4 MUC5AC

3.26e-0619253559261098ccb52306f837f632ebaea45b90ad30fe
ToppCellEnterocyte_Progenitors-C_06|Enterocyte_Progenitors / shred on cell type and cluster

MUC5B MUC12 MUC4 MUC5AC MUC6

3.26e-06192535b9938e1a929c00628cc6ebfdf10cf285167f445c
ToppCellASK440-Epithelial-Secretory|ASK440 / Donor, Lineage and Cell class of Lung cells from Dropseq

VANGL2 FSIP2 COL7A1 MUC5B MUC4

3.35e-0619353550e98d91697c7af6a3de39e52edde6dd2b67b512
ToppCellNS-critical-LOC-Epithelial-Secretory|LOC / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

DSG2 MUC16 MUC5B MUC4 MUC5AC

3.52e-06195535b0d782eeee30c797b4da9b3be29b864983fd9e71
ToppCellBronchial-NucSeq-Epithelial-Epi_airway_secretory|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

SHANK2 MUC16 MUC5B MUC4 MUC5AC

3.52e-06195535e7230a849ea31e6eef9bc6f5468938499450582d
ToppCell5'-GW_trimst-2-LargeIntestine-Epithelial-goblet|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

NXPE4 NXPE1 MUC5B NXPE2 MUC4

3.52e-0619553509605533aa5947bb2e5a6725c1ce89f79d330bf5
ToppCell5'-GW_trimst-2-LargeIntestine-Epithelial-goblet-Goblet_cell|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

NXPE4 NXPE1 MUC5B NXPE2 MUC4

3.52e-061955357ff04c45a02df01e3816f3c1d43585a93182a730
ToppCell(05)_Secretory|World / shred by cell type by condition

MUC16 MUC5B MUC4 MUC5AC PARM1

3.61e-061965358032c25b51ef96aeba28cc52686a2bd45213453d
ToppCellEnterocyte-C_05|Enterocyte / shred on cell type and cluster

NXPE4 NXPE1 MUC12 MUC4 PARM1

3.61e-06196535c307e5a70186567c62da938caa21749dc0e929d0
ToppCell3'-Broncho-tracheal-Epithelial-Epithelial_transtional-secretory-nasal_mucosa_goblet_cell-Goblet_(nasal)-Goblet_(nasal)_L.0.2.0.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

DSG2 MUC16 MUC5B MUC4 MUC5AC

3.61e-0619653560ea673ed887fe3890c5cf4ff4165384b76d7361
ToppCelldistal-Epithelial-Goblet|distal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

ASAH2 MUC16 MUC5B MUC4 MUC5AC

3.70e-06197535da1ed7303cc9cb2d205c0e5c49c52544d3540951
ToppCellBronchus_Control_(B.)|World / Sample group, Lineage and Cell type

NRG1 MUC16 MUC5B MUC4 MUC5AC

3.70e-06197535b6dff2ee108813e18657e2d8cf850e2423f8c8e9
ToppCell5'-Adult-Distal_Rectal-Epithelial-epithelial_progenitor_cell|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

NXPE1 MUC5B MUC12 MUC4 PARM1

3.70e-0619753519cf283537c853fa902852e7b8ac1139729a931a
ToppCelldistal-3-Epithelial-Goblet|3 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

ASAH2 MUC16 MUC5B MUC4 MUC5AC

3.70e-06197535a00784ccfb1de6a96b91e2a8a2889b69f31a33da
ToppCell5'-Adult-Distal_Rectal-Epithelial-epithelial_progenitor_cell-TA|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

NXPE1 MUC5B MUC12 MUC4 PARM1

3.70e-06197535e14a0e8a893c72356afc5508e3531ae0b23bfe16
ToppCelldistal-Epithelial-Goblet-3|distal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

ASAH2 MUC16 MUC5B MUC4 MUC5AC

3.70e-061975353fbf456ae4f73da4f6254a6f0d24f0ec27d7a3cc
ToppCellBAL-Severe-Epithelial-Epithelial-Basal/Club|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

DSG2 MUC16 MUC5B MUC4 MUC5AC

3.89e-06199535d04062d86643e5712cc2f519f4f36e643d404a16
ToppCellTracheal-10x5prime-Epithelial-Epi_airway_secretory|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

NAV2 MUC16 MUC5B MUC4 MUC5AC

3.89e-061995357223f853335492ca617dbec3e4b6872a8a463a45
ToppCellTracheal-10x5prime-Epithelial-Epi_submucosal-gland-SMG_Mucous|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

SHANK2 MUC16 MUC5B NXPE2 MUC5AC

3.89e-06199535f37114cf849837fdb8ed9a767de773e8681b7df3
ToppCellBAL-Severe-Epithelial-Epithelial-Basal/Club-|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

DSG2 MUC16 MUC5B MUC4 MUC5AC

3.89e-06199535a3f83fe5c3c557cd3ef8f5632f7fba5cf1859937
ToppCellBAL-Severe-Epithelial-Epithelial-Basal/Club|Severe / Location, Disease Group, Cell group, Cell class (2021.03.09)

DSG2 MUC16 MUC5B MUC4 MUC5AC

3.89e-06199535644197ff7e3299587881dd678836262e670ed4a8
ToppCellSevere_COVID-19-Epithelial-Basal/Club|Severe_COVID-19 / Disease group,lineage and cell class (2021.01.30)

DSG2 MUC16 MUC5B MUC4 MUC5AC

3.89e-061995352a0aebcfadff4e2dfc8244ad8a87c338ecccacfd
ToppCellBAL-Severe-Epithelial-Epithelial-Basal/Club-|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

DSG2 MUC16 MUC5B MUC4 MUC5AC

3.89e-06199535fd364f43859b2e7a3e91ce6a1c430cc42ad26a49
ToppCellBronchial-NucSeq-Epithelial-Epi_submucosal-gland|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

SHANK2 MUC16 MUC5B NXPE2 MGAM2

3.98e-0620053585c0f038bcfb42669dca2b80273b0f8a1421405e
ToppCellTCGA-Stomach-Primary_Tumor-Stomach_Adenocarcinoma-Stomach_Adenocarcinoma_-_Mucinous|TCGA-Stomach / Sample_Type by Project: Shred V9

COL7A1 NXPE1 MUC12 NXPE2

2.15e-05137534291b4eeaf21ec951695621161dbc2de3e82ca993
ToppCellTCGA-Stomach-Primary_Tumor-Stomach_Adenocarcinoma-Stomach_Adenocarcinoma_-_Mucinous-3|TCGA-Stomach / Sample_Type by Project: Shred V9

NXPE4 NXPE1 MUC12 NXPE2

2.90e-05148534c95a732163050cfb5d604c2a4c9eb1afa9f19a95
ToppCellAT1-AT2_cells-Myositis-ILD_01|World / lung cells shred on cell class, cell subclass, sample id

VANGL2 NRG1 DSG2 MUC4

3.75e-051585343bc51cfd37b289cc3e866b54ce55a298e5eff690
ToppCellwk_20-22-Epithelial-Proximal_epithelial-SMG_basal_1|wk_20-22 / Celltypes from embryonic and fetal-stage human lung

COL7A1 SHANK2 MUC5B MGAM2

3.75e-05158534adad97e6cf479d42791c5ba9cbc5f15f469322bf
ToppCell3'-Broncho-tracheal-Epithelial-Epithelial_transtional-secretory-nasal_mucosa_goblet_cell-Goblet_(nasal)-Goblet_(nasal)_L.0.2.2.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

MUC16 MUC5B MUC4 MUC5AC

3.84e-0515953460b1f4dce2ce0911160fda17f137c064da31e2eb
ToppCellChildren_(3_yrs)-Epithelial-lung_goblet_cell-D032|Children_(3_yrs) / Lineage, Cell type, age group and donor

SHANK2 MUC16 MUC5B MUC4

4.03e-051615342d63b279d9a5132e1c09b03930bf9039036d24a2
ToppCell5'-Airway_Nasal_SMG-Epithelial-Epithelial_transtional-secretory|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

SHANK2 DSG2 MUC5B MGAM2

4.23e-05163534f6847f47a8856c0d4136c1af317432d45eccfde9
ToppCell5'-Airway_Nasal_SMG-Epithelial-Epithelial_transtional-secretory-SMG_acinar_cell-SMG_duct|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

SHANK2 DSG2 MUC5B MGAM2

4.23e-05163534a1fbefe53523a9879a4d4b493071059798b5f917
ToppCell5'-Airway_Nasal_SMG|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

SHANK2 DSG2 MUC5B MGAM2

4.23e-05163534d8450bf9c6d2ec5dd1472952c9e65f82f995337a
ToppCell5'-Airway_Nasal_SMG-Epithelial|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

SHANK2 DSG2 MUC5B MGAM2

4.23e-05163534454a5e87e2f9f66e38cc5aa1b433c47b54c9be42
ToppCell5'-Airway_Nasal_SMG-Epithelial-Epithelial_transtional-secretory-SMG_acinar_cell-SMG_duct-SMG_duct_L.0.6.2.0|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

SHANK2 DSG2 MUC5B MGAM2

4.23e-05163534be6cc44df9a2b10dce1a353717c279c3558f8fec
ToppCell5'-Airway_Nasal_SMG-Epithelial-Epithelial_transtional-secretory-SMG_acinar_cell|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

SHANK2 DSG2 MUC5B MGAM2

4.23e-05163534d9bd9d90cfa4e85d5ea51f8f3ee14a700571f508
ToppCellAdult-Epithelial-lung_goblet_cell-D175|Adult / Lineage, Cell type, age group and donor

MUC16 MUC5B MUC4 MUC5AC

4.34e-051645346e6aedb61f8e195d52e028fdda750a29bb14e57e
ToppCellTCGA-Colorectal|World / Sample_Type by Project: Shred V9

NXPE4 NXPE1 MUC12 NXPE2

4.55e-05166534c018cd8c7a82251c67e3dc812d4d21e527a43456
ToppCell368C-Fibroblasts-Fibroblast-J_(Lipofibroblast)|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)

SHANK2 DSG2 NXPE4 MUC16

4.76e-05168534e870d2e69316406f45112ed0bf324b24f902a99e
ToppCellControl|World / group, cell type (main and fine annotations)

SHANK2 NAV2 MUC5AC PARM1

4.76e-05168534a3511faf2cd2c2b9c8363c8b99da3f3609c43ed6
ToppCell368C-Fibroblasts-Fibroblast-J_(Lipofibroblast)-|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)

SHANK2 DSG2 NXPE4 MUC16

4.76e-05168534403aba73a0f9ffb32252288d075fad8a588ca440
ToppCell3'-Pediatric_IBD-SmallIntestine-Epithelial-Tuft-related-Microfold_cell|Pediatric_IBD / Celltypes from developing, pediatric, Crohn's, & adult GI tract

VANGL2 MUC5B MUC5AC MUC6

4.87e-05169534a54a8494c1feff29d77ab4737fcfabc84ace5c94
ToppCell3'-GW_trimst-2-LargeIntestine-Epithelial-epithelial_progenitor_cell-Stem_cells|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

DSG2 NXPE1 MUC5B MUC3A

5.10e-051715343a2fefcb62e9d47ae6b3a946c45d3f2dd32c576c
ToppCell3'-GW_trimst-2-LargeIntestine-Epithelial-epithelial_progenitor_cell|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

DSG2 NXPE1 MUC5B MUC3A

5.10e-051715343ef44a5e3e8f81424f1e9aa302860b6688a549b8
ToppCellControl-Epithelial_cells-Airway_basal|Control / group, cell type (main and fine annotations)

NRG1 COL7A1 CACHD1 MUC4

5.10e-051715343965ced4be6db14265a90673502fceee425837ca
ToppCell390C-Lymphocytic-ILC|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)

UBAP2 ASAH2 NAV2 BICRAL

5.10e-0517153470963f79711fe6088d6d01b29206b17ab89e5e73
ToppCelldroplet-Liver-Hepatocytes-21m-Myeloid-Kupffer_cell|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ANKS6 NXPE4 PIAS1 SPRED3

5.22e-05172534574ebdf36e45222bcd907cd2c2ee7ff50ed4573a
ToppCelldroplet-Liver-Hepatocytes-21m-Myeloid|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ANKS6 NXPE4 PIAS1 SPRED3

5.22e-051725341627fa7035b0e0bbc82a1c0f000d8231254c680a
ToppCellChildren_(3_yrs)-Epithelial-lung_goblet_cell-D139|Children_(3_yrs) / Lineage, Cell type, age group and donor

MUC16 MUC5B MUC4 MUC5AC

5.34e-05173534464267a2ff3f5c387b6c9c6fa4dab135a221f448
ToppCell5'-Adult-Distal_Rectal-Epithelial-goblet-BEST2+_Goblet_cell|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

NAV2 MUC5B MUC12 MUC4

5.58e-05175534019ea30ac55748463d7917abf3d3f0e804189bfd
ToppCellwk_15-18-Epithelial-Proximal_epithelial-Proximal_secretory_3|wk_15-18 / Celltypes from embryonic and fetal-stage human lung

ANKS6 DSG2 MUC16 MUC4

5.71e-051765348d9d0fb46c418b2067be58aec822e8c2b1561461
ToppCellnucseq-Epithelial-Epithelial_Airway-Basal/Suprabasal-Basal|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

NRG1 COL7A1 CACHD1 MUC4

5.83e-05177534ce86dfaeb74d995a19aea62f0fb15c4c0bb854b0
ToppCellnucseq-Epithelial-Epithelial_Airway-Basal/Suprabasal|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

NRG1 COL7A1 CACHD1 MUC4

5.83e-05177534cbad1a23851151dbef01ea2af960e6f0944f838b
ToppCellBAL-Severe-Epithelial-Epithelial-undefined_Epi-|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

MUC16 MUC5B MUC4 MUC5AC

5.96e-051785349a3ef66814dfca7b37024e7f79e86ea8c72ae10f
ToppCellBAL-Severe-Epithelial-Epithelial-undefined_Epi|Severe / Location, Disease Group, Cell group, Cell class (2021.03.09)

MUC16 MUC5B MUC4 MUC5AC

5.96e-0517853419b5432aa1d7f616d58a106543c18cf2d7ca840c
ToppCellBAL-Severe-Epithelial-Epithelial-undefined_Epi-|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

MUC16 MUC5B MUC4 MUC5AC

5.96e-05178534b413a634283550fa224db7d0d05956e3f64694a1
ToppCell5'-Adult-Distal_Rectal-Epithelial-goblet|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

NAV2 MUC5B MUC12 MUC4

5.96e-051785349099b47e0756d6a1b7ba1c6aa7b47c5425f649e0
ToppCellBAL-Severe-Epithelial-Epithelial-undefined_Epi|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

MUC16 MUC5B MUC4 MUC5AC

5.96e-0517853449a2271718637522f74334068d252963ee13b1ce
ToppCell3'-Broncho-tracheal-Epithelial-Epithelial_transtional-secretory-nasal_mucosa_goblet_cell-Goblet_(nasal)-Goblet_(nasal)_L.0.2.0.5|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

MUC16 MUC5B MUC4 MUC5AC

6.09e-051795346e965e424eebef50f0202cff75f458be395cfca1
ToppCell3'-GW_trimst-2-LargeIntestine-Epithelial-epithelial_progenitor_cell-TA|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

COL7A1 DSG2 NXPE1 MUC5B

6.23e-05180534271ee52ed8f21f78ddf68e52fc88fe582701675e
ToppCellCiliated_cells-A-Donor_07|World / lung cells shred on cell class, cell subclass, sample id

MUC16 MUC5B MUC4 MUC5AC

6.23e-05180534d9be152773fe9f2160edad9246fa03c03afeafd6
ToppCellFetal_29-31_weeks-Epithelial-alveolar_epithelial_cell_type_1/2_(AT1/AT2-like)-D088|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

SHANK2 NAV2 CACHD1 MUC4

6.36e-05181534576da14ab3107f89e1f44a4a439d1bef5bb42370
ToppCellPCW_05-06-Epithelial-Epithelial_neuroendo-epi_neuroendocrine2[NE2]_(12)|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung

NRG1 MUC5B MUC5AC MUC6

6.50e-05182534dc29e8735c3562ce32322351d28f7d9709208ebf
ToppCellCOVID-19-Epithelial_cells-ECM-high_epithelial|COVID-19 / group, cell type (main and fine annotations)

NRG1 SHANK2 DSG2 NAV2

6.64e-05183534dc1d380bf7564f290256cb7108063d1bd2da732b
ToppCelldroplet-Heart-HEART_(LV+RV_ONLY)-30m-Endothelial-endocardial_endothelial_cells|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

VANGL2 NRG1 DSG2 CACHD1

6.64e-05183534b0b5a41f1a40f9c946d0dc8b67eaccdd9f9b73a5
ToppCellCOPD-Epithelial-Basal|COPD / Disease state, Lineage and Cell class

COL7A1 SHANK2 CACHD1 MUC4

6.64e-051835340f760e393edc91009bf6c7e02eeac039a1dfb4ed
ToppCell3'-Pediatric_IBD-SmallIntestine-Epithelial-Tuft-related|Pediatric_IBD / Celltypes from developing, pediatric, Crohn's, & adult GI tract

DSG2 MUC5B MUC5AC MUC6

6.64e-05183534263937906ddabc798bbe60f0da28ba859a5c72e2
ToppCellAdult-Epithelial-alveolar_epithelial_cell_type_2/Club-like_(AT2/Club-like)|Adult / Lineage, Cell type, age group and donor

SHANK2 CACHD1 MUC4 PARM1

6.92e-05185534673f0c688ae6984bc8027df2da335787924f4137
ToppCellfacs-Lung-24m-Hematologic-myeloid-myeloid_dendritic_cell-Ccr7+_dendritic|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

DCLRE1C MLLT6 TMEM131 TMEM123

6.92e-0518553419fa853f6f746ccf232a343b3c9c7a5e55800409
ToppCellControl-Epithelial-Club|World / Disease state, Lineage and Cell class

SHANK2 NAV2 CACHD1 MUC4

7.07e-051865349798428691408e17ff2af2fe2d1b345f074d67e4
ToppCellCOPD-Epithelial-Club|World / Disease state, Lineage and Cell class

SHANK2 NAV2 MUC4 PARM1

7.07e-051865343006f4ab1eaf1eb34c10ca9f7c869603d2d25744
ToppCellTCGA-Pancreas-Primary_Tumor-Pancreatic_Adenocarcinoma-Ductal_Adenocarcinoma-1|TCGA-Pancreas / Sample_Type by Project: Shred V9

ZNF146 APC TMEM131 SAP130

7.07e-0518653403db813598b67b1e08f759758a1c2023396921fa
Drugcellobiitol

MUC12 MUC3A MUC4 MUC5AC

1.51e-0637524CID000003871
DrugCamptothecine (S,+) [7689-03-4]; Down 200; 11.4uM; PC3; HT_HG-U133A

APC NAV2 FOXJ3 PIAS1 JMJD1C NUP153

3.38e-061805264541_DN
Drugguanidine hydrochloride

TBCCD1 MUC12 MUC3A MUC4 MUC5AC

1.13e-05129525CID000005742
DrugAsbestos, Crocidolite

NRG1 PDE4DIP EPC1 NAV3 NAV2 OR7A17 PIAS2 ATF2 PIAS1 JMJD1C MED12 MAP3K5

1.77e-0512415212ctd:D017638
Diseasecholangiocarcinoma (is_marker_for)

MUC16 MUC5B MUC3A MUC4 MUC5AC MUC6

1.21e-0964506DOID:4947 (is_marker_for)
Diseasemucinous adenocarcinoma (is_marker_for)

MUC4 MUC5AC MUC6

4.57e-085503DOID:3030 (is_marker_for)
Diseasepancreatic ductal carcinoma (is_marker_for)

MUC5B MUC3A MUC4 MUC5AC

3.54e-0661504DOID:3587 (is_marker_for)
Diseasekeratoconjunctivitis (is_marker_for)

MUC16 MUC5AC

8.43e-063502DOID:9368 (is_marker_for)
Diseasepancreatic cancer (is_marker_for)

MUC16 MUC4 MUC5AC MUC6

2.64e-05101504DOID:1793 (is_marker_for)
DiseaseSUN domain-containing protein 3 measurement

NXPE4 NXPE1

2.80e-055502EFO_0802102
Diseaseficolin-2 measurement

NXPE4 NXPE1

2.80e-055502EFO_0008135
Diseasecorpus callosum anterior volume measurement

NAV3 NAV2 FAM171B

4.01e-0539503EFO_0010295
Diseasebiliary tract benign neoplasm (is_marker_for)

MUC4 MUC5AC

5.88e-057502DOID:0050625 (is_marker_for)
Diseasecommon bile duct neoplasm (is_marker_for)

MUC4 MUC5AC

7.83e-058502DOID:4608 (is_marker_for)
Diseasedry eye syndrome (is_marker_for)

MUC16 MUC5AC

1.26e-0410502DOID:10140 (is_marker_for)
Diseaseotitis media (is_marker_for)

MUC5B MUC4

1.26e-0410502DOID:10754 (is_marker_for)
Diseasefetuin-B measurement

NRG1 JMJD1C

1.26e-0410502EFO_0008128
Diseasegastrin-releasing peptide measurement

NRG1 JMJD1C

1.53e-0411502EFO_0022000
Diseasepulmonary fibrosis

MUC5B MUC5AC

1.53e-0411502EFO_0009448
Diseasehematologic cancer (implicated_via_orthology)

PIAS2 PIAS1

2.17e-0413502DOID:2531 (implicated_via_orthology)
Diseasegastric ulcer (implicated_via_orthology)

MUC5AC MUC6

2.53e-0414502DOID:10808 (implicated_via_orthology)
Diseasemannan-binding lectin serine protease 1 measurement

NXPE4 NXPE1

2.91e-0415502EFO_0008223
Diseaseinterleukin 10 measurement

NXPE4 NXPE2 JMJD1C

3.18e-0478503EFO_0004750
Diseaseotitis media (biomarker_via_orthology)

MUC4 MUC5AC

3.77e-0417502DOID:10754 (biomarker_via_orthology)
Diseasesusceptibility to pneumonia measurement

MUC5B PIAS2 MUC5AC

6.03e-0497503EFO_0008410
DiseaseSjogren's syndrome (is_marker_for)

MUC16 MUC5AC

7.58e-0424502DOID:12894 (is_marker_for)
Diseasegallstones

MUC5AC JMJD1C NUP153

8.25e-04108503EFO_0004210
DiseaseHirschsprung Disease

NRG1 MED12

1.27e-0331502C0019569
Diseaseeosinophil percentage of leukocytes

TMEM131 MBD5 MUC5AC PIAS1 JMJD1C FBXW7

1.58e-03746506EFO_0007991
DiseaseCOVID-19 symptoms measurement

MUC5B MUC5AC

1.62e-0335502EFO_0600019

Protein segments in the cluster

PeptideGeneStartEntry
TTTVVTGTSEHSISH

VANGL2

71

Q9ULK5
TQTSSSHSALSHQVT

EPC1

726

Q9H2F5
SSHHEASTQETSESS

MLLT6

281

P55198
VTISHTIHSSSTQLS

CACHD1

786

Q5VU97
TIHSSSTQLSSGHTV

CACHD1

791

Q5VU97
SPHTEAIQHSSVSTS

ATF2

446

P15336
TAHTSTVLTATATTT

MUC5B

2016

Q9HC84
TSHTPAATTSTTQHS

MUC5B

3491

Q9HC84
VHSISNSSHSSITSA

RAPH1

201

Q70E73
HYTSTAHHSTTVTQT

NRG1

336

Q02297
TTSSTRVTKHSTVQH

DSG2

1101

Q14126
TTLVSEETNTHHSTS

MUC16

411

Q8WXI7
TVITHVSSGDATTHV

MUC16

4326

Q8WXI7
KVRTSSSVHESHSSV

MUC16

9816

Q8WXI7
TTAPSTNHSTIHSTS

MUC4

611

Q99102
TNHSTIHSTSTSPQE

MUC4

616

Q99102
HVTDASSVSTGHATS

MUC4

1906

Q99102
THHAEATSTSTTNIT

MUC6

1701

Q6W4X9
THHPEVTSTSTTSIT

MUC6

1756

Q6W4X9
THTVIITTHTQMATS

MUC6

2021

Q6W4X9
ITTHTQMATSASIHS

MUC6

2026

Q6W4X9
TTHITQFATPHSATT

MGAM2

2381

Q2M2H8
HSATTTTLALSHTSL

MGAM2

2391

Q2M2H8
QHSTATQSSTATQTS

ASAH2

71

Q9NR71
IIHSSEQSTVSDHNS

JMJD1C

461

Q15652
SSISSSVHQISLHNS

FSIP2

1191

Q5CZC0
SFTSSITTTENATHS

MUC3A

2126

Q02505
ITTTETTSHSAHSFT

MUC3A

2311

Q02505
FTSSITTTETNSHST

MUC3A

2341

Q02505
ESVSSINSATSHSSI

NAV3

1671

Q8IVL0
GVSSHSSHVISAQST

MED12

311

Q93074
NHTTTVNTINSIHSS

LRRC4C

606

Q9HCJ2
STSHVSVSKTTHSQP

MUC5AC

3501

P98088
STASVSKTSTSHVSV

MUC5AC

3926

P98088
ASVTTNHSSTVTSTQ

PARM1

171

Q6UWI2
THNSSVTSAASSVTI

TMEM123

136

Q8N131
SLSVSSNSVHHVQTI

BICRAL

406

Q6AI39
HISSQNSSQSTHITE

DCLRE1C

531

Q96SD1
STVSTHPHSNQSSLS

FOXJ3

336

Q9UPW0
EHTHTNSVTNSSSIV

FBXW7

136

Q969H0
HTAESSVSSSSSHRQ

ANKS6

746

Q68DC2
SHVQRVQHSASTSLS

MBD5

421

Q9P267
TVHVTQASSSSVTIT

COL7A1

691

Q02388
DQTTSTTHINHISTV

FAM171B

401

Q6P995
HVNTTTSATHSTATI

NXPE1

91

Q8N323
TSVTTTSSHESSTHV

PIAS2

581

O75928
FSQSSSLTVHVRSHT

ZNF146

221

Q15072
SGVSTLSSTVSHDSQ

MAP3K5

1221

Q99683
LSSTVSHDSQSAHRS

MAP3K5

1226

Q99683
THVNTTTSATHSTAT

NXPE2

101

Q96DL1
RPFTHVNTTTSATHS

NXPE4

86

Q6UWF7
VNTTTSATHSTATIL

NXPE4

91

Q6UWF7
DSVSSINSATSHSSV

NAV2

1801

Q8IVL1
TSAATHNSHTSATAS

OR7A17

261

O14581
VSSNSLRESHSHTVT

PIAS1

616

O75925
SRSSSDHHLETTSTI

SHANK2

1496

Q9UPX8
DHHLETTSTISTVSS

SHANK2

1501

Q9UPX8
HETASVLSSSSTHSA

APC

286

P25054
AALSSSTSHTHASVE

UBAP2

716

Q5T6F2
HASVESASSHQSSAT

UBAP2

726

Q5T6F2
QIHTSSSSQTHVSSS

UBN2

886

Q6ZU65
TSHVDSDSSSSHSRQ

SPRED3

141

Q2MJR0
HSSHATAVTTSNIPV

SAP130

416

Q9H0E3
ITLVSISATTSHFHA

TMEM131

141

Q92545
SSSAHHVTTVNSTNC

NUP153

571

P49790
FSQSSSLATHQTVHT

ZNF841

266

Q6ZN19
QLTASFHSTHSSLVS

TBCCD1

191

Q9NVR7
QTTESSQSFVAVHHS

PJA2

111

O43164
TETTVFPHSTTTSVH

MUC12

1311

Q9UKN1
ESTAFQTHPASTHTT

MUC12

2216

Q9UKN1
EESRTSHSSTTHTIS

MUC12

4771

Q9UKN1
SHETTITQQSVSDSH

PDE4DIP

226

Q5VU43