Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	X11-like protein binding	CLSTN3 CLSTN2	7.88e-05	3	103	2	GO:0042988
GeneOntologyMolecularFunction	cytoskeletal protein binding	CLSTN3 LIMA1 ANK2 MAP2 KIF26B SPTA1 FHOD3 CLSTN2 ADNP HNRNPK MAPK8IP3 CEP350 NF1 TRIM32 FAM83D USH2A	1.55e-04	1099	103	16	GO:0008092
GeneOntologyMolecularFunction	kinesin binding	CLSTN3 CLSTN2 MAPK8IP3 FAM83D	1.86e-04	55	103	4	GO:0019894
GeneOntologyMolecularFunction	calcium ion binding	DCHS2 CLSTN3 ASAH2 SPTA1 PCDHB11 PCDHA6 CLSTN2 EDEM3 MEGF8 PLCH2 CABS1 DSG4	4.77e-04	749	103	12	GO:0005509
GeneOntologyBiologicalProcess	cell-cell adhesion via plasma-membrane adhesion molecules	DCHS2 CLSTN3 CD177 PCDHB11 PCDHA6 CLSTN2 NECTIN3 TENM4 DSG4	2.53e-05	313	102	9	GO:0098742
GeneOntologyBiologicalProcess	homophilic cell adhesion via plasma membrane adhesion molecules	DCHS2 CLSTN3 PCDHB11 PCDHA6 CLSTN2 NECTIN3 DSG4	4.02e-05	187	102	7	GO:0007156
GeneOntologyCellularComponent	axon	EPHB2 HDAC5 MAP2 MYCBP2 SPTA1 HMBS NECTIN3 ADNP HNRNPK MAPK8IP3 NF1 SACS USH2A DYNC1H1	1.47e-04	891	105	14	GO:0030424
Domain	CADHERIN_1	DCHS2 CLSTN3 PCDHB11 PCDHA6 CLSTN2 DSG4	3.22e-05	113	100	6	PS00232
Domain	Cadherin	DCHS2 CLSTN3 PCDHB11 PCDHA6 CLSTN2 DSG4	3.22e-05	113	100	6	PF00028
Domain	CADHERIN_2	DCHS2 CLSTN3 PCDHB11 PCDHA6 CLSTN2 DSG4	3.39e-05	114	100	6	PS50268
Domain	-	DCHS2 CLSTN3 PCDHB11 PCDHA6 CLSTN2 DSG4	3.39e-05	114	100	6	2.60.40.60
Domain	CA	DCHS2 CLSTN3 PCDHB11 PCDHA6 CLSTN2 DSG4	3.56e-05	115	100	6	SM00112
Domain	Cadherin-like	DCHS2 CLSTN3 PCDHB11 PCDHA6 CLSTN2 DSG4	3.74e-05	116	100	6	IPR015919
Domain	Cadherin	DCHS2 CLSTN3 PCDHB11 PCDHA6 CLSTN2 DSG4	4.11e-05	118	100	6	IPR002126
Domain	Calsyntenin	CLSTN3 CLSTN2	8.48e-05	3	100	2	IPR026914
Domain	ARM-type_fold	RTTN FHOD3 HEATR5A ECPAS WDFY4 FOCAD NF1 CFAP69 STAG2	8.58e-05	339	100	9	IPR016024
Domain	ARM-like	RTTN FHOD3 HEATR5A ECPAS WDFY4 NF1 CFAP69 STAG2	1.02e-04	270	100	8	IPR011989
Domain	-	RTTN HEATR5A ECPAS WDFY4 NF1 CFAP69	1.24e-03	222	100	6	1.25.10.10
Domain	HTH_Tnp_Tc5	DCHS2 POGZ	2.13e-03	13	100	2	PF03221
Domain	NHL	TENM4 TRIM32	2.13e-03	13	100	2	PS51125
Domain	Cadherin_CS	DCHS2 PCDHB11 PCDHA6 DSG4	2.80e-03	109	100	4	IPR020894
Domain	-	PPIP5K1 UBASH3B	5.06e-03	20	100	2	3.40.50.1240
Domain	His_PPase_superfam	PPIP5K1 UBASH3B	5.06e-03	20	100	2	IPR029033
Pubmed	Chr21 protein-protein interactions: enrichment in proteins involved in intellectual disability, autism, and late-onset Alzheimer's disease.	EPRS1 DCHS2 CLSTN3 ANK2 MYCBP2 BIRC2 POGZ REV3L HNRNPK MAPK8IP3 CEP350 FOCAD UBE2O TCERG1 SACS TRIM32 ZNF197 MIB1 MKLN1 USP54 BTRC DYNC1H1	2.75e-11	1285	104	22	35914814
Pubmed	Prediction of the coding sequences of mouse homologues of KIAA gene: II. The complete nucleotide sequences of 400 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.	ATMIN ZHX3 CLSTN3 HDAC5 HEATR5A POGZ FOCAD LRFN2 TENM4 MEGF8 CHST15 PPIP5K1 DYNC1H1	2.98e-10	407	104	13	12693553
Pubmed	SRCAP complex promotes lung cancer progression by reprograming the oncogenic transcription of Hippo-YAP/TAZ signaling pathway.	EPRS1 LIMA1 MYCBP2 POGZ TEAD4 ADNP HNRNPK LUZP1 ESF1 MED15 UBE2O TCERG1 TNKS1BP1 DYNC1H1	1.10e-09	549	104	14	38280479
Pubmed	A central chaperone-like role for 14-3-3 proteins in human cells.	PABIR1 LIMA1 MAP2 MYCBP2 KIF26B RAB11FIP2 PRAG1 LUZP1 CEP350 NF1 MEGF8 TCERG1 PRMT5 TNKS1BP1 USP54	4.39e-08	861	104	15	36931259
Pubmed	KCTD13-mediated ubiquitination and degradation of GluN1 regulates excitatory synaptic transmission and seizure susceptibility.	TOM1L2 EPRS1 LIMA1 ANK2 MAP2 PPFIA4 SPTA1 RTN3 HNRNPK LUZP1 MAPK8IP3 UBE2O TENM4 NF1 SACS PRMT5 TNKS1BP1 USP54 DYNC1H1	4.49e-08	1431	104	19	37142655
Pubmed	Qualitative and quantitative analyses of protein phosphorylation in naive and stimulated mouse synaptosomal preparations.	TOM1L2 ANK2 MAP2 MYCBP2 SYTL2 RTN3 MAPK8IP3 NF1 SACS TNKS1BP1	9.77e-08	347	104	10	17114649
Pubmed	Large-scale characterization of HeLa cell nuclear phosphoproteins.	EPRS1 ZHX3 LIMA1 MYCBP2 TATDN2 POGZ ECPAS HNRNPK ESF1 MAPK8IP3 NF1 TNKS1BP1 STAG2	5.66e-07	774	104	13	15302935
Pubmed	Proximity interactions among centrosome components identify regulators of centriole duplication.	CCDC14 MYCBP2 CEP350 UBE2O MIB1 USP54	6.22e-07	101	104	6	24613305
Pubmed	Neuron-specific protein network mapping of autism risk genes identifies shared biological mechanisms and disease-relevant pathologies.	EPRS1 ANK2 MAP2 MYCBP2 RAB11FIP2 PSMB6 RTN3 TACC2 MAPK8IP3 UBE2O UBXN4 TENM4 NF1 MKLN1 BTRC	1.53e-06	1139	104	15	36417873
Pubmed	An organelle-specific protein landscape identifies novel diseases and molecular mechanisms.	LIMA1 GALC HDAC5 MYCBP2 RADX RAB11FIP2 STYXL2 LUZP1 ESF1 MKS1 MED15 NF1 TRIM32 MKLN1 TNKS1BP1 DYNC1H1	1.96e-06	1321	104	16	27173435
Pubmed	TBR1 regulates autism risk genes in the developing neocortex.	ANK2 POGZ ADNP	2.15e-06	9	104	3	27325115
Pubmed	TNF-α inhibits glucocorticoid receptor-induced gene expression by reshaping the GR nuclear cofactor profile.	ZHX3 MUC16 REV3L ESF1 CEP350 MED15 NF1 MEGF8 MIB1 DSG4 STAG2	3.47e-06	638	104	11	31182584
Pubmed	Functional proteomics establishes the interaction of SIRT7 with chromatin remodeling complexes and expands its role in regulation of RNA polymerase I transcription.	MYCBP2 POGZ ECPAS ADNP ESF1 UBE2O NF1 PRMT5 TNKS1BP1 STAG2 DYNC1H1	4.32e-06	653	104	11	22586326
Pubmed	A dual-activity topoisomerase complex regulates mRNA translation and turnover.	ATMIN TPRA1 MYCBP2 RTTN ANKLE1 REV3L PRAG1 MAPK8IP3 FOCAD MEGF8 CHST15 TNKS1BP1 DYNC1H1 RIC1	5.48e-06	1105	104	14	35748872
Pubmed	Protein interaction network of the mammalian Hippo pathway reveals mechanisms of kinase-phosphatase interactions.	LIMA1 HDAC5 TRIM41 RAB11FIP2 ECPAS LUZP1 NF1 TRIM32 USP54	8.11e-06	446	104	9	24255178
Pubmed	Tumor suppressor BAP1 nuclear import is governed by transportin-1.	TOM1L2 EPRS1 LIMA1 MYCBP2 HEBP2 PSMB6 ECPAS HNRNPK LUZP1 ESF1 UBE2O TCERG1 PRMT5 DYNC1H1	8.52e-06	1149	104	14	35446349
Pubmed	A convergent mechanism of high risk factors ADNP and POGZ in neurodevelopmental disorders.	POGZ ADNP	8.86e-06	2	104	2	35775424
Pubmed	[Molecular Mechanism of Action of hnRNP K and RTN3 in the Replication of Enterovirus 71].	RTN3 HNRNPK	8.86e-06	2	104	2	26164948
Pubmed	Neurofibromin interacts with the cytoplasmic Dynein Heavy Chain 1 in melanosomes of human melanocytes.	NF1 DYNC1H1	8.86e-06	2	104	2	23583712
Pubmed	PRMT5-mediated histone arginine methylation antagonizes transcriptional repression by polycomb complex PRC2.	PRMT5 COMMD10	8.86e-06	2	104	2	32025719
Pubmed	WDFY4 polymorphisms in Chinese patients with anti-MDA5 dermatomyositis is associated with rapid progressive interstitial lung disease.	WDFY4 IFIH1	8.86e-06	2	104	2	36637178
Pubmed	Ubiquitin ligase and signalling hub MYCBP2 is required for efficient EPHB2 tyrosine kinase receptor function.	EPHB2 MYCBP2	8.86e-06	2	104	2	38289221
Pubmed	PINK1 Content in Mitochondria is Regulated by ER-Associated Degradation.	EPRS1 LIMA1 RADX HNRNPK LUZP1 UBE2O TRIM32 PRMT5 DYNC1H1	1.38e-05	477	104	9	31300519
Pubmed	A protein-protein interaction network for human inherited ataxias and disorders of Purkinje cell degeneration.	CCDC14 ZHX3 PPFIA4 HNRNPK CEP350 MED15 MEGF8 SACS TRIM32 USP54	1.48e-05	608	104	10	16713569
Pubmed	Nuclear actin interactome analysis links actin to KAT14 histone acetyl transferase and mRNA splicing.	EPRS1 ZHX3 LIMA1 ADNP LUZP1 ESF1 UBE2O TCERG1 DYNC1H1	2.20e-05	506	104	9	30890647
Pubmed	N-Terminal Acetyltransferase Naa40p Whereabouts Put into N-Terminal Proteoform Perspective.	EPRS1 ZHX3 LIMA1 ANK2 TACC2 ADNP HNRNPK ESF1 UBE2O R3HCC1L TCERG1 TNKS1BP1	2.36e-05	934	104	12	33916271
Pubmed	Comprehensive proteomic analysis of interphase and mitotic 14-3-3-binding proteins.	LIMA1 HDAC5 MYCBP2 SPTA1 HNRNPK DYNC1H1	2.39e-05	190	104	6	15161933
Pubmed	Calsyntenin-3 interacts with the sodium-dependent vitamin C transporter-2 to regulate vitamin C uptake.	CLSTN3 CLSTN2	2.65e-05	3	104	2	34673103
Pubmed	The calsyntenins--a family of postsynaptic membrane proteins with distinct neuronal expression patterns.	CLSTN3 CLSTN2	2.65e-05	3	104	2	12498782
Pubmed	LUZP1 and the tumor suppressor EPLIN modulate actin stability to restrict primary cilia formation.	LIMA1 LUZP1	2.65e-05	3	104	2	32496561
Pubmed	Synaptotagmin 2 couples mucin granule exocytosis to Ca2+ signaling from endoplasmic reticulum.	ANK2 SYTL2	2.65e-05	3	104	2	19208631
Pubmed	Interactomes of Glycogen Synthase Kinase-3 Isoforms.	KIF26B LUZP1 HELB CEP350 UBE2O TNKS1BP1	4.08e-05	209	104	6	36779422
Pubmed	Phosphoproteome analysis of the human mitotic spindle.	LIMA1 TRIM41 ESF1 CEP350 NF1 FAM83D	4.19e-05	210	104	6	16565220
Pubmed	Proteomic profiling of VCP substrates links VCP to K6-linked ubiquitylation and c-Myc function.	EPRS1 MYCBP2 PSMB6 POGZ ADNP HNRNPK LUZP1 ESF1 NF1 TCERG1 TRIM32 MIB1 BTRC DYNC1H1	5.15e-05	1353	104	14	29467282
Pubmed	TRIM32 protein sensitizes cells to tumor necrosis factor (TNFα)-induced apoptosis via its RING domain-dependent E3 ligase activity against X-linked inhibitor of apoptosis (XIAP).	BIRC2 TRIM32	5.29e-05	4	104	2	21628460
Pubmed	YAP ISGylation increases its stability and promotes its positive regulation on PPP by stimulating 6PGL transcription.	TEAD4 BTRC	5.29e-05	4	104	2	35149670
Pubmed	Differential effects of neurofibromin gene dosage on melanocyte development.	NF1 COMMD10	5.29e-05	4	104	2	22810304
Pubmed	Identification of proximal SUMO-dependent interactors using SUMO-ID.	LIMA1 TACC2 ADNP HNRNPK LUZP1 MED15 TCERG1 TNKS1BP1	5.86e-05	444	104	8	34795231
Pubmed	A systems-wide screen identifies substrates of the SCFβTrCP ubiquitin ligase.	EPRS1 TATDN2 TRIM32 USP54 BTRC DYNC1H1	7.27e-05	232	104	6	25515538
Pubmed	Destabilization of Atoh1 by E3 Ubiquitin Ligase Huwe1 and Casein Kinase 1 Is Essential for Normal Sensory Hair Cell Development.	MYCBP2 CEP350 SACS DYNC1H1	8.20e-05	76	104	4	27542412
Pubmed	PRMT5 Regulates DNA Repair by Controlling the Alternative Splicing of Histone-Modifying Enzymes.	PRMT5 COMMD10	8.80e-05	5	104	2	30184499
Pubmed	Plectin and IFAP-300K are homologous proteins binding to microtubule-associated proteins 1 and 2 and to the 240-kilodalton subunit of spectrin.	MAP2 SPTA1	8.80e-05	5	104	2	3027087
Pubmed	T-type calcium channels functionally interact with spectrin (α/β) and ankyrin B.	ANK2 SPTA1	8.80e-05	5	104	2	29720258
Pubmed	JNK/stress-activated protein kinase associated protein 1 is required for early development of telencephalic commissures in embryonic brains.	MAP2 MAPK8IP3	8.80e-05	5	104	2	21685723
Pubmed	Comparative host-coronavirus protein interaction networks reveal pan-viral disease mechanisms.	TOM1L2 MYCBP2 RADX ECPAS CEP350 EDEM3 TRIM32 MIB1 COMMD10 USP54	9.03e-05	754	104	10	33060197
Pubmed	MKRN2 Physically Interacts with GLE1 to Regulate mRNA Export and Zebrafish Retinal Development.	TOM1L2 EPRS1 MYCBP2 PSMB6 PRMT5 MIB1 DYNC1H1	1.04e-04	358	104	7	32460013
Pubmed	N-Terminomics for the Identification of In Vitro Substrates and Cleavage Site Specificity of the SARS-CoV-2 Main Protease.	EPRS1 LIMA1 ADNP HNRNPK LUZP1 TNKS1BP1 DYNC1H1	1.08e-04	360	104	7	33111431
Pubmed	PRISMA and BioID disclose a motifs-based interactome of the intrinsically disordered transcription factor C/EBPα.	EPRS1 ZHX3 MYCBP2 HEBP2 POGZ ECPAS ADNP HNRNPK MED15 TCERG1 STAG2 DYNC1H1	1.15e-04	1103	104	12	34189442
Pubmed	The Deubiquitinase USP37 Regulates Chromosome Cohesion and Mitotic Progression.	POGZ ADNP STAG2 BTRC	1.21e-04	84	104	4	26299517
Pubmed	The PHLPP1 N-Terminal Extension Is a Mitotic Cdk1 Substrate and Controls an Interactome Switch.	EPRS1 LIMA1 KIF26B LUZP1 TNKS1BP1 DYNC1H1	1.25e-04	256	104	6	33397691
Pubmed	Novel cadherin-related membrane proteins, Alcadeins, enhance the X11-like protein-mediated stabilization of amyloid beta-protein precursor metabolism.	CLSTN3 CLSTN2	1.32e-04	6	104	2	12972431
Pubmed	Analysis of erythrocyte and platelet membrane proteins in various forms of beta-thalassemia.	ANK2 SPTA1	1.32e-04	6	104	2	15310273
Pubmed	Sarm1, a negative regulator of innate immunity, interacts with syndecan-2 and regulates neuronal morphology.	MAP2 NF1	1.32e-04	6	104	2	21555464
Pubmed	PARD3 induces TAZ activation and cell growth by promoting LATS1 and PP1 interaction.	TEAD4 BTRC	1.32e-04	6	104	2	26116754
Pubmed	Genome-wide CRISPR screen identifies HNRNPL as a prostate cancer dependency regulating RNA splicing.	ATMIN TPRA1 MAP2 MYCBP2 HEBP2 RTN3 ECPAS CERT1 MAPK8IP3 LRFN2 MKLN1 CFAP69 STAG2 RIC1	1.42e-04	1489	104	14	28611215
Pubmed	Histone methyltransferase DOT1L coordinates AR and MYC stability in prostate cancer.	TOM1L2 MYCBP2 TRIM32 FAM83D USP54 DYNC1H1	1.47e-04	264	104	6	32814769
Pubmed	Spatiotemporal profile of postsynaptic interactomes integrates components of complex brain disorders.	LIMA1 ANK2 MYCBP2 ADNP HNRNPK LUZP1 MAPK8IP3 UBE2O NF1 UBASH3B DYNC1H1	1.48e-04	963	104	11	28671696
Pubmed	Loss of ER retention motif of AGR2 can impact mTORC signaling and promote cancer metastasis.	EPRS1 MYCBP2 SPTA1 PSMB6 RTN3 CLSTN2 ECPAS HNRNPK PRMT5 DYNC1H1	1.57e-04	807	104	10	30575818
Pubmed	An interactome perturbation framework prioritizes damaging missense mutations for developmental disorders.	CCDC14 TRIM41 RTN3 POGZ CERT1 HNRNPK TRIM32 BTRC	1.61e-04	514	104	8	29892012
Pubmed	A dual-strategy expression screen for candidate connectivity labels in the developing thalamus.	EPHB2 CLSTN3 CLSTN2 TENM4	1.65e-04	91	104	4	28558017
Pubmed	Heme-stress activated NRF2 skews fate trajectories of bone marrow cells from dendritic cells towards red pulp-like macrophages in hemolytic anemia.	SPTA1 COMMD10	1.84e-04	7	104	2	35031770
Pubmed	Neuronal distribution of spatial in the developing cerebellum and hippocampus and its somatodendritic association with the kinesin motor KIF17.	GALC MAP2	1.84e-04	7	104	2	17961552
Pubmed	FIH-1, a novel interactor of mindbomb, functions as an essential anti-angiogenic factor during zebrafish vascular development.	PRMT5 MIB1	1.84e-04	7	104	2	25347788
Pubmed	Coordinated metabolism of Alcadein and amyloid beta-protein precursor regulates FE65-dependent gene transactivation.	CLSTN3 CLSTN2	1.84e-04	7	104	2	15037614
Pubmed	DNA damage shifts circadian clock time via Hausp-dependent Cry1 stabilization.	EPRS1 MYCBP2 HNRNPK PRMT5 DYNC1H1	1.87e-04	175	104	5	25756610
Pubmed	Prediction of the coding sequences of mouse homologues of KIAA gene: III. the complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.	POGZ ECPAS ADNP UBE2O UBXN4 PLCH2 MIB1 TNKS1BP1	1.95e-04	529	104	8	14621295
Pubmed	Synaptic GAP and GEF Complexes Cluster Proteins Essential for GTP Signaling.	ANK2 PRAG1 LUZP1 NF1 SACS DYNC1H1	2.06e-04	281	104	6	28706196
Pubmed	Novel Cul3 binding proteins function to remodel E3 ligase complexes.	WDFY4 LRFN2 TRIM32	2.37e-04	40	104	3	25011449
Pubmed	Mediator complex recruits epigenetic regulators via its two cyclin-dependent kinase subunits to repress transcription of immune response genes.	MED15 PRMT5	2.45e-04	8	104	2	23749998
Pubmed	Molecular genetics of successful smoking cessation: convergent genome-wide association study results.	TACC2 CLSTN2 WDFY4 USH2A	2.47e-04	101	104	4	18519826
Pubmed	Identifying biological pathways that underlie primordial short stature using network analysis.	EPRS1 LIMA1 MYCBP2 ADNP HNRNPK CEP350 NF1 SACS PRMT5 STAG2 DYNC1H1	2.52e-04	1024	104	11	24711643
Pubmed	A scan of chromosome 10 identifies a novel locus showing strong association with late-onset Alzheimer disease.	ASAH2 TACC2 WDFY4 R3HCC1L CHST15 USP54 BTRC	2.58e-04	415	104	7	16385451
Pubmed	The Deubiquitinating Enzyme USP48 Interacts with the Retinal Degeneration-Associated Proteins UNC119a and ARL3.	TOM1L2 EPRS1 LIMA1 MAP2 PSMB6 RTN3 HNRNPK DYNC1H1	2.60e-04	552	104	8	36293380
Pubmed	Proximity-dependent biotin identification (BioID) reveals a dynamic LSD1-CoREST interactome during embryonic stem cell differentiation.	HDAC5 MYCBP2 POGZ ECPAS ADNP LUZP1 TNKS1BP1	2.69e-04	418	104	7	34709266
Pubmed	A comprehensive resource of interacting protein regions for refining human transcription factor networks.	EPRS1 ANK2 MAP2 SYTL2 TCERG1	2.81e-04	191	104	5	20195357
Pubmed	Protein interaction studies in human induced neurons indicate convergent biology underlying autism spectrum disorders.	ANK2 ADNP DYNC1H1	2.94e-04	43	104	3	36950384
Pubmed	A protein-protein interaction map of the TNF-induced NF-κB signal transduction pathway.	CCDC14 BIRC2 RTN3 MIB1 USP54 UBASH3B	3.03e-04	302	104	6	30561431
Pubmed	Regulation of canonical Wnt signalling by the ciliopathy protein MKS1 and the E2 ubiquitin-conjugating enzyme UBE2E1.	MKS1 R3HCC1L	3.14e-04	9	104	2	35170427
Pubmed	Gain of Additional BIRC3 Protein Functions through 3'-UTR-Mediated Protein Complex Formation.	EPRS1 RTN3 POGZ ECPAS ADNP HNRNPK ESF1 UBE2O NF1 TCERG1 PRMT5 STAG2 DYNC1H1	3.33e-04	1425	104	13	30948266
Pubmed	mTORC2 interactome and localization determine aggressiveness of high-grade glioma cells through association with gelsolin.	EPRS1 LIMA1 PSMB6 HNRNPK TNKS1BP1 DYNC1H1	3.61e-04	312	104	6	37120454
Pubmed	An antibody-based proximity labeling map reveals mechanisms of SARS-CoV-2 inhibition of antiviral immunity.	MYCBP2 RADX SYTL2 NECTIN3 CEP350 EDEM3 UBE2O UBXN4 USP54	3.62e-04	733	104	9	34672954
Pubmed	E3 ubiquitin ligase RNF123 targets lamin B1 and lamin-binding proteins.	EPRS1 KIF26B REV3L ECPAS HNRNPK FOCAD R3HCC1L PRMT5 DYNC1H1	3.73e-04	736	104	9	29676528
Pubmed	Cell organization, growth, and neural and cardiac development require αII-spectrin.	ANK2 SPTA1	3.92e-04	10	104	2	22159418
Pubmed	Perturbed hematopoiesis in mice lacking ATMIN.	ATMIN COMMD10	3.92e-04	10	104	2	27581360
Pubmed	MECP2 directly interacts with RNA polymerase II to modulate transcription in human neurons.	GALC MAP2 MYCBP2 POGZ ADNP HNRNPK TCERG1 SACS TRIM32 TNKS1BP1 DYNC1H1	4.01e-04	1082	104	11	38697112
Pubmed	Multiplexed kinase interactome profiling quantifies cellular network activity and plasticity.	EPHB2 BIRC2 ADNP PRAG1 LUZP1 ESF1 NF1 FAM83D UBASH3B BTRC	4.07e-04	910	104	10	36736316
Pubmed	MLF2 Negatively Regulates P53 and Promotes Colorectal Carcinogenesis.	HNRNPK PRMT5 MIB1	4.07e-04	48	104	3	37438558
Pubmed	Genome-wide association study identifies loci affecting blood copper, selenium and zinc.	ANK2 C4orf50 POGZ	4.33e-04	49	104	3	23720494
Pubmed	Identification of proteins that interact with alpha A-crystallin using a human proteome microarray.	LIMA1 PSMB6 TEAD4 BTRC	4.46e-04	118	104	4	24453475
Pubmed	Global landscape of HIV-human protein complexes.	EPRS1 PSMB6 RTN3 EDEM3 UBE2O BTRC DYNC1H1	4.59e-04	457	104	7	22190034
Pubmed	Fbxo45 inhibits calcium-sensitive proteolysis of N-cadherin and promotes neuronal differentiation.	MYCBP2 BTRC	4.79e-04	11	104	2	25143387
Pubmed	Deubiquitinase USP28 inhibits ubiquitin ligase KLHL2-mediated uridine-cytidine kinase 1 degradation and confers sensitivity to 5'-azacytidine-resistant human leukemia cells.	HNRNPK PRMT5	4.79e-04	11	104	2	31938050
Pubmed	A staging system for correct phenotype interpretation of mouse embryos harvested on embryonic day 14 (E14.5).	CERT1 MKS1 NF1	4.87e-04	51	104	3	28185240
Pubmed	Gsk3β and Tomm20 are substrates of the SCFFbxo7/PARK15 ubiquitin ligase associated with Parkinson's disease.	EPHB2 EPRS1 PSMB6 BIRC2 TEAD4 HNRNPK DYNC1H1	4.96e-04	463	104	7	27503909
Pubmed	LMBR1L regulates lymphopoiesis through Wnt/β-catenin signaling.	TOM1L2 EPRS1 CLSTN3 PSMB6 RTN3 ECPAS UBE2O TRIM32 STAG2 DYNC1H1	5.33e-04	942	104	10	31073040
Pubmed	USP11 deubiquitinates RAE1 and plays a key role in bipolar spindle formation.	MYCBP2 DYNC1H1	5.73e-04	12	104	2	29293652
Pubmed	Structural analysis of RIG-I-like receptors reveals ancient rules of engagement between diverse RNA helicases and TRIM ubiquitin ligases.	TRIM41 IFIH1	5.73e-04	12	104	2	33373584
Pubmed	Synergistic action of nectins and cadherins generates the mosaic cellular pattern of the olfactory epithelium.	MAP2 NECTIN3	5.73e-04	12	104	2	26929452
Pubmed	Hdac4 Interactions in Huntington's Disease Viewed Through the Prism of Multiomics.	HDAC5 HNRNPK TENM4 NF1 TCERG1 PRMT5 BTRC	5.77e-04	475	104	7	31040226
Pubmed	Construction of expression-ready cDNA clones for KIAA genes: manual curation of 330 KIAA cDNA clones.	ZHX3 HDAC5 MYCBP2 TENM4 TNKS1BP1	5.93e-04	225	104	5	12168954
Interaction	YWHAH interactions	PABIR1 LIMA1 HDAC5 MAP2 MYCBP2 KIF26B RAB11FIP2 PRAG1 HNRNPK LUZP1 CEP350 IFIH1 NF1 MEGF8 TCERG1 TRIM32 TNKS1BP1 USP54	8.29e-06	1102	101	18	int:YWHAH
Interaction	BTG3 interactions	EPRS1 MYCBP2 MAPK8IP3 TRIM32 BTRC DYNC1H1	9.89e-06	98	101	6	int:BTG3
Interaction	YWHAB interactions	PABIR1 LIMA1 HDAC5 MAP2 MYCBP2 KIF26B RAB11FIP2 RTN3 HNRNPK LUZP1 CEP350 NF1 TRIM32 PRMT5 USP54 BTRC DYNC1H1	1.09e-05	1014	101	17	int:YWHAB
Interaction	YWHAG interactions	PABIR1 LIMA1 HDAC5 MAP2 MYCBP2 KIF26B RAB11FIP2 RTN3 PRAG1 LUZP1 CEP350 NF1 TCERG1 TRIM32 PRMT5 PPIP5K1 USP54 BTRC DYNC1H1	1.22e-05	1248	101	19	int:YWHAG
Interaction	CCDC50 interactions	LIMA1 KCNE3 IFIH1 MIB1 BTRC	2.49e-05	69	101	5	int:CCDC50
Interaction	YAP1 interactions	EPRS1 LIMA1 MAP2 POGZ TEAD4 ADNP HNRNPK LUZP1 ESF1 MED15 UBE2O NF1 TCERG1 PRMT5 TNKS1BP1 BTRC DYNC1H1	2.93e-05	1095	101	17	int:YAP1
Interaction	YWHAQ interactions	PABIR1 LIMA1 HDAC5 MAP2 MYCBP2 KIF26B SPTA1 RAB11FIP2 HNRNPK LUZP1 CEP350 NF1 TRIM32 PRMT5 USP54 BTRC DYNC1H1	3.81e-05	1118	101	17	int:YWHAQ
Interaction	PNMA2 interactions	EPRS1 GALC ADNP CERT1 CEP350 MKLN1 DSG4 USP54	3.86e-05	251	101	8	int:PNMA2
Interaction	DCTN1 interactions	MAP2 MYCBP2 PSMB6 ECPAS LUZP1 MAPK8IP3 CEP350 UBE2O NF1 FAM83D DYNC1H1	3.95e-05	497	101	11	int:DCTN1
Interaction	SH3PXD2A interactions	EPRS1 LIMA1 RAB11FIP2 ECPAS NF1 MIB1	4.52e-05	128	101	6	int:SH3PXD2A
Interaction	WWTR1 interactions	LIMA1 MYCBP2 POGZ TEAD4 ADNP LUZP1 UBE2O TCERG1 TNKS1BP1 BTRC	5.13e-05	422	101	10	int:WWTR1
Interaction	KCTD13 interactions	TOM1L2 EPRS1 LIMA1 ANK2 MAP2 PPFIA4 SPTA1 RTN3 HNRNPK LUZP1 MAPK8IP3 UBE2O TENM4 NF1 SACS PRMT5 TNKS1BP1 USP54 DYNC1H1	5.60e-05	1394	101	19	int:KCTD13
Interaction	TOLLIP interactions	TOM1L2 LIMA1 BIRC2 RTN3 ECPAS LUZP1 TNKS1BP1 USP54 DYNC1H1	7.91e-05	358	101	9	int:TOLLIP
Interaction	UBE2D3 interactions	MYCBP2 BIRC2 FOCAD UBE2O TRIM32 MIB1 UBASH3B BTRC	8.95e-05	283	101	8	int:UBE2D3
Interaction	TOP3B interactions	ATMIN EPRS1 LIMA1 TPRA1 MYCBP2 TRIM41 RTTN ANKLE1 REV3L PRAG1 MAPK8IP3 FOCAD MEGF8 CHST15 PRMT5 MIB1 TNKS1BP1 DYNC1H1 RIC1	1.13e-04	1470	101	19	int:TOP3B
GeneFamily	Cadherin related	DCHS2 CLSTN3 CLSTN2	2.17e-05	17	59	3	24
GeneFamily	Zinc fingers C2H2-type\|ZF class homeoboxes and pseudogenes	ZHX3 ADNP	1.07e-03	15	59	2	529
GeneFamily	Bardet-Biedl syndrome associated\|BBSome	MKS1 TRIM32	2.11e-03	21	59	2	980
ToppCell	Bronchial-NucSeq-Stromal-Myofibroblastic\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	SYTL2 JPH2 FHOD3 CLSTN2 SACS FAM83D	7.56e-06	200	104	6	a66449b22b39dd6987fc2c3ed160d24564234ced
ToppCell	frontal_cortex-Neuronal-GABAergic_neuron-Lamp5-Lamp5_Fam19a1_Pax6\|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	ZHX3 LIMA1 FMO1 RADX FAM83D	9.62e-06	121	104	5	7f2057367777c6c92f596054cbc5fe567d079fbc
ToppCell	droplet-Lung-30m-Hematologic-myeloid-intermediate_monocyte-intermediate_monocyte_l33\|30m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	ZHX3 SPTA1 RAB11FIP2 REV3L MEGF8	1.70e-05	136	104	5	a43b3db1754c619d328a26a2ba6af4756629a723
ToppCell	droplet-Liver-Hepatocytes-24m-Myeloid-Kupffer_cell\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CCDC14 GALC RTTN WDFY4 TENM4	4.04e-05	163	104	5	8dc0128eeede933537e3bcc5d6ec0322711552f3
ToppCell	droplet-Liver-Hepatocytes-24m-Myeloid-Kupffer_cell\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CCDC14 GALC RTTN WDFY4 TENM4	4.04e-05	163	104	5	fd243ca223079033be480a24817a399f281fa4d4
ToppCell	metastatic_Lymph_Node-Myeloid_cells-Microglia/Mac\|metastatic_Lymph_Node / Location, Cell class and cell subclass	TPRA1 KCNE3 STYXL2 CERT1 MEGF8	5.22e-05	172	104	5	f673a2e697b46e7cfa4186cb3fb2b98e3c83703e
ToppCell	RV-11._Adipocyte\|RV / Chamber and Cluster_Paper	LIMA1 MYCBP2 RTN3 TENM4 PPIP5K1	6.14e-05	178	104	5	278bbea5cf8f0589f71675c7a3d00679391b5253
ToppCell	renal_papilla_nuclei-Hypertensive_with+without-CKD-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Proximal_Tubule_Epithelial_Cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	EPHB2 FHOD3 CLSTN2 TENM4 UBASH3B	6.14e-05	178	104	5	a0ab20c588e7d43d0320d4779d9ab95c1c86e297
ToppCell	COVID-19-kidney-Epi_(Mes)\|kidney / Disease (COVID-19 only), tissue and cell type	DCHS2 MAP2 KIF26B JPH2 FHOD3	6.30e-05	179	104	5	e7c9dc63f03d3f3746b51a7e3c8393089e2ceb7d
ToppCell	droplet-Heart-nan-24m-Mesenchymal-smooth_muscle_cell\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MAP2 CLSTN2 LRFN2 PLCH2 TNKS1BP1	6.47e-05	180	104	5	78fdcfb3fdbf36469cae78407cda5bd0996930d8
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Epithelial-Renal_corpuscle_epithelial_cell-parietal_epithelial_cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	DCHS2 MAP2 KIF26B JPH2 LRFN2	6.64e-05	181	104	5	5f2d3a08577c440c944778d07aa993c6e7873f3d
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Epithelial-Renal_corpuscle_epithelial_cell-parietal_epithelial_cell-Parietal_Epithelial_Cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	DCHS2 MAP2 KIF26B JPH2 LRFN2	6.64e-05	181	104	5	c7c5f7d4c397b4613c772413a0a679377efffff3
ToppCell	Fetal_29-31_weeks-Immune-enucleated_erythrocyte-D150\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	SPTA1 HMBS ANKLE1 UBE2O FAM83D	7.37e-05	185	104	5	c4bf3ac684c1a8876b51f7af4d3a62dc47e961ee
ToppCell	PCW_13-14-Mesenchymal-Mesenchymal_fibroblastic-mes_Arw_fibro_(16)\|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung	EPHB2 ANK2 MAP2 TENM4 CHST15	7.37e-05	185	104	5	7dcdc009c5681ee05dd18968f7e85c3403fe34af
ToppCell	15-Trachea-Epithelial-Multiciliated_precursor\|Trachea / Age, Tissue, Lineage and Cell class	CCDC14 RTTN HEATR5A CEP350 WDR49	7.37e-05	185	104	5	9a8b8360d99375b726ca8e3c9a3f9b08919892d7
ToppCell	Fetal_29-31_weeks-Immune-enucleated_erythrocyte-D088\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	SPTA1 HMBS ANKLE1 UBE2O FAM83D	7.37e-05	185	104	5	e8f7da9641b6cf1db1093b4f301ce828fd3a529c
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Medullary_Thick_Ascending_Limb_Cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	TOM1L2 ZHX3 ANK2 FHOD3 TENM4	7.37e-05	185	104	5	03f64a7132b13a01ba47187e0e15c13ac88f7cb2
ToppCell	wk_20-22-Hematologic-Meg-ery-Definitive_reticulocyte\|wk_20-22 / Celltypes from embryonic and fetal-stage human lung	SPTA1 HMBS ANKLE1 UBE2O FAM83D	7.37e-05	185	104	5	4a2c85e292d4cbce80e92992ded5d66a3aa446ee
ToppCell	Immune-enucleated_erythrocyte\|World / Lineage, Cell type, age group and donor	SPTA1 HMBS ANKLE1 UBE2O FAM83D	7.56e-05	186	104	5	f9d5ec5cc8fd6e63bf25abe390307ec8a4a2d5a3
ToppCell	PCW_07-8.5-Mesenchymal-Mesenchymal_fibroblastic-mes_Arw_fibro_(16)\|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung	EPHB2 ANK2 MAP2 TENM4 CHST15	7.56e-05	186	104	5	4d68ee3d32f7ef884faf402ef92b31b0eb4656f1
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	TOM1L2 ZHX3 ANK2 FHOD3 TENM4	7.56e-05	186	104	5	1850583d23903d08226aeb0edb3e07b0994330e4
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Epithelial-Distal_tubule_epithelial_cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	TOM1L2 ZHX3 ANK2 FHOD3 TENM4	7.56e-05	186	104	5	4dafc215c42e7949f932a3627359c107943b5d6b
ToppCell	E16.5-samps-Mesenchymal-Myofibroblast\|E16.5-samps / Age Group, Lineage, Cell class and subclass	EPHB2 ANK2 PRAG1 FOCAD TENM4	7.56e-05	186	104	5	e044b3428b7eacfdc72d0f57cdabaa1de04c74cd
ToppCell	5'-GW_trimst-2-SmallIntestine-Neuronal-neurons_A-Branch_A1_(iMN)\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	ANK2 MAP2 HEBP2 C4orf50 FHOD3	7.75e-05	187	104	5	a748b3a59e398e0da019db3f16d38adb1960c29f
ToppCell	facs-Trachea-3m-Mesenchymal-myofibroblast-tracheobronchial_smooth_muscle_cell-smooth_muscle_cell_of_trachea_l20-23\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	CLSTN3 MAP2 SYTL2 TENM4 SACS	7.75e-05	187	104	5	69b47f00598d647e2a99427ebddf42c339428e47
ToppCell	Fetal_29-31_weeks-Mesenchymal-airway_smooth_muscle_cell\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	KIF26B JPH2 TACC2 CLSTN2 UBASH3B	7.95e-05	188	104	5	4d1e5f85342ae550086609d7680e32730b78b5d2
ToppCell	Fetal_29-31_weeks-Immune-enucleated_erythrocyte\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	SPTA1 HMBS ANKLE1 UBE2O FAM83D	8.15e-05	189	104	5	1900e574870fc647bfa11c732a72f3d38aab717c
ToppCell	RV-15._Ventricular_Cardiomyocyte_III\|World / Chamber and Cluster_Paper	ANK2 FHOD3 TACC2 MAPK8IP3 USP54	8.15e-05	189	104	5	0a82931b5f6c0a6427ca3edd5e2235ac49099d40
ToppCell	RV-15._Ventricular_Cardiomyocyte_III\|RV / Chamber and Cluster_Paper	ANK2 FHOD3 TACC2 MAPK8IP3 USP54	8.35e-05	190	104	5	93c3188dfeb0b2f9889f8ae9b9c1f2f34129c99b
ToppCell	droplet-Fat-Mat-18m-Hematologic\|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SPTA1 RTTN ANKLE1 UBE2O	8.91e-05	100	104	4	ea36e4ff513d66186b92e39c549e55c26609cb30
ToppCell	droplet-Fat-Mat-18m-Hematologic-erythroblast\|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SPTA1 RTTN ANKLE1 UBE2O	8.91e-05	100	104	4	ceca7d9342e5ee7293f07edb815beee4eb010fe7
ToppCell	TCGA-Prostate-Primary_Tumor-Prostate_Adenocarcinoma-Acinar_Adenocarcinoma-6\|TCGA-Prostate / Sample_Type by Project: Shred V9	EPRS1 HEATR5A CEP350 STAG2 DYNC1H1	8.99e-05	193	104	5	abd71b2cf667ef2b1c4d88acd0c1dd19a12ff659
ToppCell	Smart-start-Cell-Wel_seq-Neoplastic-Stem-like-NPC-like-NPC-like_Prolif-E\|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	CCDC14 LIMA1 MAP2 REV3L FAM83D	9.21e-05	194	104	5	7a66bd7d4fc9c6db861cedd2487f241e406869d1
ToppCell	moderate-Epithelial-FOXN4+\|Epithelial / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls	CCDC14 RTTN REV3L CEP350 WDR49	9.21e-05	194	104	5	dff3fb10372053951d41e0ccd41aac3ece6009bd
ToppCell	Tracheal-NucSeq-Epithelial-Epi_airway_secretory\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	KCNE3 SYTL2 MUC16 TENM4 FAM83D	9.67e-05	196	104	5	b07db4a53ab9be9aad6fae5e45f9547db829d096
ToppCell	Bronchial-NucSeq-Stromal-Mesofibroblastic\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	FMO1 JPH2 MUC16 HAO1 DSG4	9.67e-05	196	104	5	96e5c6d155273e82ebafa180df8bb589c3e3e54e
ToppCell	Bronchial-NucSeq-Stromal-Mesofibroblastic-Mesothelia\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	FMO1 JPH2 MUC16 HAO1 DSG4	9.67e-05	196	104	5	ce13af36fc2932e8125013041742593ff3d07e86
ToppCell	Tracheal-NucSeq-Epithelial-Epi_airway_secretory-Secretory_Goblet\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	KCNE3 SYTL2 MUC16 TENM4 FAM83D	9.67e-05	196	104	5	c366f980cc04abfe1c0c14746c11810c812a42c0
ToppCell	facs-Limb_Muscle-ForelimbandHindlimb-3m-Mesenchymal-skeletal_muscle_satellite_cell\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ZHX3 MAP2 SYTL2 HNRNPK TENM4	9.90e-05	197	104	5	5bc11aff92da2a0aca8473f997fe7a99f3cae75d
ToppCell	Parenchymal-NucSeq-Epithelial-Epi_airway_basal-Suprabasal\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	DCHS2 KIF26B MUC16 FAM83D WDR49	1.01e-04	198	104	5	28ada093cec552262731194a04a4b9ff93186c3b
ToppCell	Parenchymal-NucSeq-Epithelial-Epi_airway_secretory-Secretory_Goblet\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	ARHGAP40 KIF26B SYTL2 MUC16 FAM83D	1.01e-04	198	104	5	af07a970afaa435c6433bb5c1cbff4c67af350c7
ToppCell	(09)_Interm._secr.>cil.-(2)_GFP_FOXI1\|(09)_Interm._secr.>cil. / shred by cell type by condition	REV3L ADNP CEP350 UBXN4 STAG2	1.04e-04	199	104	5	fc680f85ebd3bab4c72876a19a461b0afb5f51ce
ToppCell	(03)_KRT6B+-(2)_GFP_FOXI1\|(03)_KRT6B+ / shred by cell type by condition	LIMA1 REV3L CEP350 UBXN4 STAG2	1.04e-04	199	104	5	c425e7975f492ed5cfcca022248adb627e1d27d4
ToppCell	Biopsy_Control_(H.)-Epithelial-MUC5AC+_High\|Biopsy_Control_(H.) / Sample group, Lineage and Cell type	ARHGAP40 CD177 MUC16 PLCH2 FAM83D	1.04e-04	199	104	5	a5240868cea40574ed4ee45eb27a00c1812957ed
ToppCell	NS-moderate-d_0-4-Epithelial\|d_0-4 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	LIMA1 HEBP2 SYTL2 MUC16 TACC2	1.06e-04	200	104	5	64462a18afca3c1a8548a857924b8166058bf958
Drug	ICI 182,780; Down 200; 1uM; MCF7; HT_HG-U133A_EA	EPRS1 MYCBP2 CERT1 ESF1 CEP350 EDEM3 UBXN4 STAG2	1.34e-06	177	102	8	985_DN
Disease	Intellectual Disability	RTTN POGZ CERT1 HNRNPK MAPK8IP3 NF1 SACS STAG2 DYNC1H1	2.37e-05	447	101	9	C3714756
Disease	Neurodevelopmental Disorders	ANK2 POGZ ADNP CERT1	2.99e-04	93	101	4	C1535926
Disease	neutral ceramidase measurement	ASAH2 WDFY4	4.11e-04	9	101	2	EFO_0008247
Disease	Polydactyly	HNRNPK MKS1 MEGF8 TRIM32	7.13e-04	117	101	4	C0152427
Disease	leukemia	BIRC2 NF1 STAG2	8.97e-04	55	101	3	C0023418
Disease	Bardet-Biedl syndrome (is_implicated_in)	MKS1 TRIM32	1.03e-03	14	101	2	DOID:1935 (is_implicated_in)
Disease	Bardet-Biedl syndrome 1 (disorder)	MKS1 TRIM32	1.53e-03	17	101	2	C2936862
Disease	Bardet-Biedl syndrome	MKS1 TRIM32	1.71e-03	18	101	2	cv:C0752166
Disease	total cholesterol measurement, hematocrit, stroke, ventricular rate measurement, body mass index, atrial fibrillation, high density lipoprotein cholesterol measurement, coronary artery disease, diastolic blood pressure, triglyceride measurement, systolic blood pressure, heart failure, diabetes mellitus, glucose measurement, mortality, cancer	ZHX3 TEAD4 CERT1	1.73e-03	69	101	3	EFO_0000275, EFO_0000400, EFO_0000712, EFO_0001645, EFO_0003144, EFO_0004340, EFO_0004348, EFO_0004352, EFO_0004468, EFO_0004530, EFO_0004574, EFO_0004612, EFO_0006335, EFO_0006336, EFO_0007928, MONDO_0004992
Disease	seminoma (is_marker_for)	HMBS PRMT5	2.56e-03	22	101	2	DOID:4440 (is_marker_for)
Disease	brain measurement, neuroimaging measurement	ZHX3 DCHS2 MAP2 KIF26B LUZP1 CHMP7 MIB1	2.87e-03	550	101	7	EFO_0004346, EFO_0004464
Disease	Brugada Syndrome (disorder)	KCNE3 ANK2	3.05e-03	24	101	2	C1142166

Protein segments in the cluster

Peptide	Gene	Start	Entry
MKPGTWSDESSQSED	ADNP	991	Q9H2P0
TTEGASIWMERDTAN	CABS1	291	Q96KC9
MATLWLTEDEASSTG	ANKLE1	331	Q8NAG6
ESWQGTVTDTRMSDE	CLSTN3	686	Q9BQT9
SDSTVRVWDVNTGEM	BTRC	361	Q9Y297
EPTDWTTSNTEMCEV	CD177	226	Q8N6Q3
ESEMDWDDSALTITV	CLSTN2	871	Q9H4D0
GSVFTSDLMSDWSIS	CCDC14	901	Q49A88
HTEGITAIEESWESM	R3HCC1L	566	Q7Z5L2
DLTESSSMVDGDWTM	RIC1	1216	Q4ADV7
WESREVSTGTTIMAV	PSMB6	26	P28072
WATASLSVEVADMND	PCDHA6	436	Q9UN73
EQESVSVGCTSSMFW	OOSP3	21	A0A2R8YFM6
EVADSSGTVSVIMWN	RADX	266	Q6NSI4
ESQQESTLWEMQSDS	ANK2	2996	Q01484
MSDNQSWNSSGSEED	CERT1	1	Q9Y5P4
TAASDSWTVTDMTSN	MUC16	3586	Q8WXI7
DMLWPSQSSVEETSS	MUC16	8251	Q8WXI7
ADIDATTTETYMGEW	JPH2	281	Q9BR39
RNVSIGMGSSDEWSD	MAPK8IP3	326	Q9UPT6
WSMSEQSEESVGGRV	LIMA1	616	Q9UHB6
NVTFTSSATTWMEGT	HSFX4	276	A0A1B0GTS1
SMWREFDVLTSSTGE	LRIT2	291	A6NDA9
TSVESMDWDSAIQTG	HEBP2	51	Q9Y5Z4
TSSGNVWVTHEEMET	PPFIA4	906	O75335
DMTDVTVWLNSTHAS	ASAH2	431	Q9NR71
SDTFWLSTDGMVVED	MFI	141	Q8NCR3
SSISSWLSEMSAGSE	KIF26B	1276	Q2KJY2
METTNGTETWYESLH	KCNE3	1	Q9Y6H6
VSATSVWTAGAEPMS	EDEM3	31	Q9BZQ6
ADMWDVRSTNATSAI	DSG4	536	Q86SJ6
AEAFVNTWSSMGQET	COMMD10	106	Q9Y6G5
TSSVAARDAWQMTEE	ECPAS	911	Q5VYK3
AMGTSTVEITWDETD	ESF1	501	Q9H501
ETLMDSTTATAELGW	EPHB2	21	P29323
WSRSTTTQTDMDENI	FAM83D	436	Q9H4H8
MLSSWATSSIEEVAE	HAO1	106	Q9UJM8
MDVSGQETDWRSTAF	MED15	1	Q96RN5
WETLMDSRLSADTAS	MEGF8	1491	Q7Z7M0
MQISHSWEESFSLSD	PABIR1	111	Q96E09
NVTFTSSATTWMEGT	HSFX3	276	A0A1B0GWH4
WTDGMFETLTTTGTV	MIB1	271	Q86YT6
TVVMWVSASDADEAG	DCHS2	556	Q6V1P9
AGSETWSFSVAEEMQ	PCDHB11	26	Q9Y5F2
DLAWNTMESQFSSVE	ATMIN	796	O43313
EMDSVLQSSLSSESW	C4orf50	161	Q6ZRC1
SRSMSNTTEGVWEGT	FCAMR	271	Q8WWV6
EAIFMWSTDLDSVAT	HEATR5A	201	Q86XA9
VSWSDSMQADSETDT	C5orf60	266	A6NFR6
RESDFMASVDSSWIS	CHMP7	106	Q8WUX9
CSDSAVSGQWEVVTM	FMO1	116	Q01740
SWTMGTDDSPNVTDD	FHOD3	1346	Q2V2M9
EVWGMENNSSESSFA	IFIH1	236	Q9BYX4
WSDESLSMTQSETTS	CEP350	2031	Q5VT06
FEEWGSQVTVVSSDM	PRMT5	406	O14744
DTITVAAWNHSASME	LUZP1	1011	Q86V48
IAWSENVETALSSMG	DYNC1H1	1756	Q14204
VDSDTVWNEMHSSSA	HDAC5	786	Q9UQL6
GVWSLDGSDSIQETM	HMBS	281	P08397
MWTEEAGATAEAQES	CFAP69	1	A5D8W1
WSSEDFSTLNSDMGA	GALC	271	P54803
MDTEDSEGNLTTWLI	SACS	2806	Q9NZJ4
DHAMTNDVTWSEASS	HELB	991	Q8NG08
ILEVMTDSSAASDWL	FOCAD	421	Q5VW36
MDWQSSALGEITEAD	RTN3	481	O95197
STDIWDDSSLFGIDM	RTTN	421	Q86VV8
GTEVDWMDSTSEEVA	SYTL2	891	Q9HCH5
AVNMAGSVSSAWVSE	USH2A	1341	O75445
VNVEDSWAMEATASA	TRIM32	301	Q13049
SWAMEATASAASTSV	TRIM32	306	Q13049
EEEEGVFWTSGMSRS	TRIM41	101	Q8WV44
AAQGSSRSVVNMEWD	EPRS1	476	P07814
SRDMEASEEGWSQNS	TATDN2	431	Q93075
IDTNTWMLLSEDTAA	MKLN1	366	Q9UL63
MVGFSADETWDSAID	HNRNPK	336	P61978
ESGYSDDEIMELWST	POGZ	1196	Q7Z3K3
MIGSLTDGSTETFWE	MYCBP2	3756	O75592
IMEDSTILSDWTNSN	BIRC2	21	Q13490
TIIIGEASASTMWDN	CHST15	341	Q7LFX5
MDTLEEVTWANGSTA	TPRA1	1	Q86W33
GNVTSLEWETMTENE	ZNF197	251	O14709
STGVESSSMDGFWME	ARHGAP40	21	Q5TG30
MAETVWSTDTGEAVY	MKS1	1	Q9NXB0
SSSGEEMEWSDNSLL	REV3L	501	O60673
LLSDMVRSSDVSWSD	TCERG1	906	O14776
SLTEESSSSDSMWLS	STAG2	1091	Q8N3U4
IEMEAASSWQVSSFS	PLCH2	641	O75038
TLEESQSMASWEADS	STYXL2	636	Q5VZP5
SSEARESAVGQMGWS	TNKS1BP1	1181	Q9C0C2
SDTGSTVSFWMIDTG	WDR49	166	Q8IV35
TMTSADVMWQDGSVE	UBE2O	551	Q9C0C9
SGTSTVVCVWELSMT	WDFY4	2951	Q6ZS81
TDWVMGTSNQAADDD	NF1	1046	P21359
EGQMYEITEDTASSW	TENM4	376	Q6N022
MVWESSLTEESELSA	TACC2	921	O95359
EESSETWDSSMNLFS	RAB11FIP2	326	Q7L804
SSDFDELSGWMNEKT	SPTA1	376	P02549
MSSEASDVWTEANLS	PRAG1	91	Q86YV5
MEGTAGTITSNEWSS	TEAD4	1	Q15561
QGNADSEEWMSSESD	ZC3H12B	31	Q5HYM0
SEEWMSSESDPEQIS	ZC3H12B	36	Q5HYM0
TTIDDSIMDADSLWV	MAP2	1376	P11137
MEQTSTSEGWIYGTS	UBASH3B	286	Q8TF42
TDGSLQSEDWTLNME	TOM1L2	21	Q6ZVM7
VAGDDEQSTQMAASW	UBXN4	26	Q92575
MAASWEDDKVTEASS	UBXN4	36	Q92575
MGDTYSEVSENSESW	ZHX3	916	Q9H4I2
MWSLTASEGESTTAH	PPIP5K1	1	Q6PFW1
SILEVDSTASMGGWT	USP54	711	Q70EL1
VLAMWDDTATTLTAT	LRFN2	491	Q9ULH4
WEGDLGEMESTTTSF	NECTIN3	206	Q9NQS3