Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	minus-end-directed microtubule motor activity	DNAH2 DNAH14 DNAH1 DNAH8	9.33e-06	18	153	4	GO:0008569
GeneOntologyMolecularFunction	ATP hydrolysis activity	RAD51 ATP8B3 SMC1A DNAH2 SRPRA ATP13A2 ABCA10 MLH3 MDN1 ABCB8 MACF1 DNAH8 ATP2B1	3.63e-05	441	153	13	GO:0016887
GeneOntologyMolecularFunction	dynein light intermediate chain binding	DNAH2 DNAH14 DNAH1 DNAH8	5.88e-05	28	153	4	GO:0051959
GeneOntologyMolecularFunction	ATP-dependent activity	RAD51 ATP8B3 SMC1A DNAH2 SRPRA ATP13A2 ABCA10 DNAH14 DNAH1 MLH3 MDN1 ABCB8 MACF1 DNAH8 ATP2B1	7.76e-05	614	153	15	GO:0140657
GeneOntologyMolecularFunction	dynein intermediate chain binding	DNAH2 DNAH14 DNAH1 DNAH8	1.80e-04	37	153	4	GO:0045505
GeneOntologyMolecularFunction	ribonucleoside triphosphate phosphatase activity	RAD51 ATP8B3 SMC1A DNAH2 SRPRA ARL8A ATP13A2 ABCA10 MLH3 MDN1 ARL8B ABCB8 MACF1 DNAH8 ATP2B1 DNM2	3.07e-04	775	153	16	GO:0017111
GeneOntologyMolecularFunction	pyrophosphatase activity	RAD51 ATP8B3 SMC1A DNAH2 SRPRA ARL8A ATP13A2 ABCA10 MLH3 MDN1 ARL8B ABCB8 MACF1 DNAH8 ATP2B1 DNM2	7.26e-04	839	153	16	GO:0016462
GeneOntologyMolecularFunction	hydrolase activity, acting on acid anhydrides	RAD51 ATP8B3 SMC1A DNAH2 SRPRA ARL8A ATP13A2 ABCA10 MLH3 MDN1 ARL8B ABCB8 MACF1 DNAH8 ATP2B1 DNM2	7.36e-04	840	153	16	GO:0016817
GeneOntologyMolecularFunction	hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides	RAD51 ATP8B3 SMC1A DNAH2 SRPRA ARL8A ATP13A2 ABCA10 MLH3 MDN1 ARL8B ABCB8 MACF1 DNAH8 ATP2B1 DNM2	7.36e-04	840	153	16	GO:0016818
Domain	Dynein_heavy_chain_D4_dom	DNAH2 DNAH14 DNAH1 DNAH8	3.76e-06	14	150	4	IPR024317
Domain	Dynein_HC_stalk	DNAH2 DNAH14 DNAH1 DNAH8	3.76e-06	14	150	4	IPR024743
Domain	ATPase_dyneun-rel_AAA	DNAH2 DNAH1 MDN1 DNAH8	3.76e-06	14	150	4	IPR011704
Domain	MT	DNAH2 DNAH14 DNAH1 DNAH8	3.76e-06	14	150	4	PF12777
Domain	AAA_8	DNAH2 DNAH14 DNAH1 DNAH8	3.76e-06	14	150	4	PF12780
Domain	AAA_5	DNAH2 DNAH1 MDN1 DNAH8	3.76e-06	14	150	4	PF07728
Domain	DHC_fam	DNAH2 DNAH14 DNAH1 DNAH8	5.09e-06	15	150	4	IPR026983
Domain	Dynein_heavy	DNAH2 DNAH14 DNAH1 DNAH8	5.09e-06	15	150	4	PF03028
Domain	Dynein_heavy_dom	DNAH2 DNAH14 DNAH1 DNAH8	5.09e-06	15	150	4	IPR004273
Domain	CUT	ONECUT2 ONECUT1 ONECUT3	1.74e-05	7	150	3	PS51042
Domain	CUT	ONECUT2 ONECUT1 ONECUT3	1.74e-05	7	150	3	PF02376
Domain	CUT_dom	ONECUT2 ONECUT1 ONECUT3	1.74e-05	7	150	3	IPR003350
Domain	CUT	ONECUT2 ONECUT1 ONECUT3	1.74e-05	7	150	3	SM01109
Domain	AAA	RAD51 DNAH2 SRPRA ABCA10 MDN1 ABCB8 DNAH8	1.64e-04	144	150	7	SM00382
Domain	AAA+_ATPase	RAD51 DNAH2 SRPRA ABCA10 MDN1 ABCB8 DNAH8	1.64e-04	144	150	7	IPR003593
Domain	Dynein_heavy_dom-2	DNAH2 DNAH1 DNAH8	1.73e-04	14	150	3	IPR013602
Domain	DHC_N2	DNAH2 DNAH1 DNAH8	1.73e-04	14	150	3	PF08393
Domain	ARM-type_fold	UBQLN1 ARMC3 EFR3A KPNA7 XPO6 EIF4G2 PRKDC HECTD1 AGBL1 UNC79	4.22e-04	339	150	10	IPR016024
Domain	RasGEFN	RAPGEF6 RAPGEF4 SOS1	5.24e-04	20	150	3	SM00229
Domain	RasGEF_N	RAPGEF6 RAPGEF4 SOS1	6.07e-04	21	150	3	PF00618
Domain	Ras-like_Gua-exchang_fac_N	RAPGEF6 RAPGEF4 SOS1	6.99e-04	22	150	3	IPR000651
Domain	RASGEF_NTER	RAPGEF6 RAPGEF4 SOS1	6.99e-04	22	150	3	PS50212
Domain	Ubiquilin	UBQLN1 UBQLN3	9.41e-04	6	150	2	IPR015496
Domain	-	RAD51 SMC1A DNAH2 SRPRA ARL8A ABCA10 DNAH14 DNAH1 MDN1 ARL8B HS2ST1 ABCB8 DNAH8 DNM2 NLRP8	9.98e-04	746	150	15	3.40.50.300
Domain	HECT	NEDD4L HERC3 HECTD1	1.29e-03	27	150	3	PF00632
Domain	HECTc	NEDD4L HERC3 HECTD1	1.29e-03	27	150	3	SM00119
Domain	HECT_dom	NEDD4L HERC3 HECTD1	1.29e-03	27	150	3	IPR000569
Domain	-	ONECUT2 ONECUT1 ONECUT3	1.29e-03	27	150	3	1.10.260.40
Domain	HECT	NEDD4L HERC3 HECTD1	1.29e-03	27	150	3	PS50237
Domain	AlbA_2	SLFN12 SLFNL1	1.31e-03	7	150	2	PF04326
Domain	Schlafen	SLFN12 SLFNL1	1.31e-03	7	150	2	IPR029684
Domain	Schlafen_AAA_dom	SLFN12 SLFNL1	1.31e-03	7	150	2	IPR007421
Domain	P-loop_NTPase	RAD51 SMC1A DNAH2 SRPRA ARL8A ABCA10 DNAH14 DNAH1 MDN1 ARL8B HS2ST1 ABCB8 CAMTA1 DNAH8 DNM2 NLRP8	1.32e-03	848	150	16	IPR027417
Domain	Lambda_DNA-bd_dom	ONECUT2 ONECUT1 ONECUT3	1.59e-03	29	150	3	IPR010982
Domain	RASGEF_CAT	RAPGEF6 RAPGEF4 SOS1	1.59e-03	29	150	3	PS50009
Domain	DHC_N1	DNAH2 DNAH8	1.74e-03	8	150	2	PF08385
Domain	Calx_beta	ADGRV1 FREM2	1.74e-03	8	150	2	SM00237
Domain	Dynein_heavy_dom-1	DNAH2 DNAH8	1.74e-03	8	150	2	IPR013594
Domain	RasGEF	RAPGEF6 RAPGEF4 SOS1	1.76e-03	30	150	3	PF00617
Domain	-	RAPGEF6 RAPGEF4 SOS1	1.76e-03	30	150	3	1.10.840.10
Domain	RASGEF_cat_dom	RAPGEF6 RAPGEF4 SOS1	1.76e-03	30	150	3	IPR001895
Domain	RasGEF	RAPGEF6 RAPGEF4 SOS1	1.76e-03	30	150	3	SM00147
Domain	Ras_GEF_dom	RAPGEF6 RAPGEF4 SOS1	1.76e-03	30	150	3	IPR023578
Pathway	REACTOME_ION_CHANNEL_TRANSPORT	ATP8B3 NEDD4L TRPM7 ATP13A2 NALCN CLCNKB ATP2B1 UNC79 MCOLN3	1.79e-05	176	119	9	MM15718
Pathway	REACTOME_ION_CHANNEL_TRANSPORT	ATP8B3 NEDD4L TRPM7 ATP13A2 NALCN CLCNKB ATP2B1 UNC79 MCOLN3	2.44e-05	183	119	9	M997
Pubmed	OC-3, a novel mammalian member of the ONECUT class of transcription factors.	ONECUT2 ONECUT1 ONECUT3	8.51e-08	3	154	3	11944891
Pubmed	OC-2, a novel mammalian member of the ONECUT class of homeodomain transcription factors whose function in liver partially overlaps with that of hepatocyte nuclear factor-6.	ONECUT2 ONECUT1 ONECUT3	8.51e-08	3	154	3	9915796
Pubmed	ONECUT transcription factors induce neuronal characteristics and remodel chromatin accessibility.	ONECUT2 ONECUT1 ONECUT3	8.51e-08	3	154	3	31049588
Pubmed	Identifications of novel host cell factors that interact with the receptor-binding domain of the SARS-CoV-2 spike protein.	UBR1 GGNBP2 RAPGEF6 MAP1B SLCO4A1 EXOC3 SRPRA TUBGCP4 MADD PHKA2 FREM2 RINT1 PAM PLCB3 DNM2	2.27e-07	650	154	15	38777146
Pubmed	A central chaperone-like role for 14-3-3 proteins in human cells.	RAPGEF6 HIVEP2 NEDD4L MAP1B TRPM7 PATZ1 LAMC1 EDC4 LARP1B MADD MDN1 NCOA7 MACF1 HECTD1 ATP2B1 EDRF1 SPATA13	3.08e-07	861	154	17	36931259
Pubmed	Cloning and embryonic expression pattern of the mouse Onecut transcription factor OC-2.	ONECUT2 ONECUT1 ONECUT3	3.39e-07	4	154	3	12971999
Pubmed	Biochemical Reduction of the Topology of the Diverse WDR76 Protein Interactome.	MAP1B SMC1A HNRNPM LAMC1 EDC4 FREM2 MDN1 PRKDC DNM2	6.34e-07	219	154	9	31353912
Pubmed	The transcription factor hepatocyte nuclear factor-6/Onecut-1 controls the expression of its paralog Onecut-3 in developing mouse endoderm.	ONECUT2 ONECUT1 ONECUT3	1.69e-06	6	154	3	15381696
Pubmed	Genome-wide CRISPR screen identifies HNRNPL as a prostate cancer dependency regulating RNA splicing.	HIVEP2 B3GNTL1 NEDD4L MAP1B TTC21A TMEM63B ADGRV1 PPM1K DNAH14 DNAH1 LRFN2 PTPRG HS2ST1 RBM5 MACF1 SNTG2 CTBP1 CAMTA1 HECTD1 ATP2B1 SMG6	2.81e-06	1489	154	21	28611215
Pubmed	Isolation of several human axonemal dynein heavy chain genes: genomic structure of the catalytic site, phylogenetic analysis and chromosomal assignment.	DNAH2 DNAH1 DNAH8	2.94e-06	7	154	3	9256245
Pubmed	Chr21 protein-protein interactions: enrichment in proteins involved in intellectual disability, autism, and late-onset Alzheimer's disease.	EXOSC9 HIVEP2 SUPT20H UBQLN1 TRPM7 SMC1A RAPGEF4 ETS2 MADD RNF123 CIAO3 EIF4G2 MACF1 CTBP1 PRKDC HECTD1 ZMYM5 DNM2 SOS1	4.46e-06	1285	154	19	35914814
Pubmed	In-Depth In Vivo Crosslinking in Minutes by a Compact, Membrane-Permeable, and Alkynyl-Enrichable Crosslinker.	GGNBP2 ARMC3 MAP1B EML6 HNRNPM DNAH2 ARL8A RNF17 RINT1 UTP18 MDN1 ARL8B CIAO3 FAM186A RBM5 MACF1 PRKDC DNAH8 ATP2B1 SPATA13	6.34e-06	1442	154	20	35575683
Pubmed	Spatiotemporal profile of postsynaptic interactomes integrates components of complex brain disorders.	NEDD4L PATZ1 RAPGEF4 HNRNPM SPECC1L EDC4 GABBR2 MYEF2 PTPN9 MDN1 MACF1 CTBP1 UNC79 SPATA13 DNM2 SMG6	6.38e-06	963	154	16	28671696
Pubmed	A multi-factor trafficking site on the spliceosome remodeling enzyme BRR2 recruits C9ORF78 to regulate alternative splicing.	EXOSC9 SMC1A EXOC3 SRPRA EDC4 TUBGCP4 PTPN9 UTP18 HS2ST1 EIF4G2 BAG6 DNM2	8.15e-06	560	154	12	35241646
Pubmed	Large-scale characterization of HeLa cell nuclear phosphoproteins.	UBR1 RAPGEF6 SMC1A SLCO4A1 UTP18 MDN1 XPO6 EIF4G2 ELF1 PLCB3 PRKDC BAG6 DNM2 SOS1	9.72e-06	774	154	14	15302935
Pubmed	Onecut Factors and Pou2f2 Regulate the Distribution of V2 Interneurons in the Mouse Developing Spinal Cord.	ONECUT2 ONECUT1 ONECUT3	9.99e-06	10	154	3	31231191
Pubmed	Drosophila Topors is a RING finger-containing protein that functions as a ubiquitin-protein isopeptide ligase for the hairy basic helix-loop-helix repressor protein.	ARL8A ARL8B	1.95e-05	2	154	2	14871887
Pubmed	Dose-dependent regulation of horizontal cell fate by Onecut family of transcription factors.	ONECUT2 ONECUT1	1.95e-05	2	154	2	32790713
Pubmed	An N-terminally acetylated Arf-like GTPase is localised to lysosomes and affects their motility.	ARL8A ARL8B	1.95e-05	2	154	2	16537643
Pubmed	Presynaptic Biogenesis Requires Axonal Transport of Lysosome-Related Vesicles.	ARL8A ARL8B	1.95e-05	2	154	2	30174114
Pubmed	[RAD51 regulates REV1 recruitment to DNA double-strand <br/>break sites].	RAD51 REV1	1.95e-05	2	154	2	30465533
Pubmed	Rad51 and DNA-PKcs are involved in the generation of specific telomere aberrations induced by the quadruplex ligand 360A that impair mitotic cell progression and lead to cell death.	RAD51 PRKDC	1.95e-05	2	154	2	21773671
Pubmed	Onecut-2 knockout mice fail to thrive during early postnatal period and have altered patterns of gene expression in small intestine.	ONECUT2 ONECUT3	1.95e-05	2	154	2	20354101
Pubmed	The Mass1frings mutation underlies early onset hearing impairment in BUB/BnJ mice, a model for the auditory pathology of Usher syndrome IIC.	CDH23 ADGRV1	1.95e-05	2	154	2	15820310
Pubmed	Onecut transcription factors are required for the second phase of development of the A13 dopaminergic nucleus in the mouse.	ONECUT2 ONECUT1 ONECUT3	2.36e-05	13	154	3	22102297
Pubmed	LRF maintains genome integrity by regulating the non-homologous end joining pathway of DNA repair.	SMC1A HNRNPM MDN1 PRKDC DNM2	2.76e-05	79	154	5	26446488
Pubmed	Characterization of an exchangeable gene trap using pU-17 carrying a stop codon-beta geo cassette.	CCNL2 NEDD4L PTPRG ELF1 SLC39A14 CAMTA1 HECTD1 ATP2B1 SMG6 SOS1 REV1	2.91e-05	536	154	11	15840001
Pubmed	The Onecut transcription factors HNF-6/OC-1 and OC-2 regulate early liver expansion by controlling hepatoblast migration.	ONECUT2 ONECUT1 THBS4	2.99e-05	14	154	3	17936262
Pubmed	Onecut factors control development of the Locus Coeruleus and of the mesencephalic trigeminal nucleus.	ONECUT2 ONECUT1 ONECUT3	2.99e-05	14	154	3	22534286
Pubmed	Genome wide expression profiling of the mesodiencephalic region identifies novel factors involved in early and late dopaminergic development.	ONECUT2 ONECUT1 ONECUT3	2.99e-05	14	154	3	23213462
Pubmed	Identification of dynein heavy chain genes expressed in human and mouse testis: chromosomal localization of an axonemal dynein gene.	DNAH2 DNAH1 DNAH8	2.99e-05	14	154	3	9373155
Pubmed	Exchangeable gene trap using the Cre/mutated lox system.	CCNL2 NEDD4L PTPRG ELF1 SLC39A14 CAMTA1 HECTD1 ATP2B1 SMG6 SOS1 REV1	3.01e-05	538	154	11	10512203
Pubmed	The Onecut Transcription Factors Regulate Differentiation and Distribution of Dorsal Interneurons during Spinal Cord Development.	ONECUT2 ONECUT1 ONECUT3	4.57e-05	16	154	3	28603487
Pubmed	Dynamic expression of the Onecut transcription factors HNF-6, OC-2 and OC-3 during spinal motor neuron development.	ONECUT2 ONECUT1 ONECUT3	4.57e-05	16	154	3	19800948
Pubmed	Identifying biological pathways that underlie primordial short stature using network analysis.	EXOSC9 NEDD4L MAP1B RBM12B SMC1A EXOC3 LAMC1 SPECC1L EDC4 MYEF2 MDN1 MACF1 PRKDC ATP2B1 BAG6	5.35e-05	1024	154	15	24711643
Pubmed	Multiple mouse chromosomal loci for dynein-based motility.	DNAH2 DNAH14 DNAH1 DNAH8	5.69e-05	47	154	4	8812413
Pubmed	Mutations in UNC80, Encoding Part of the UNC79-UNC80-NALCN Channel Complex, Cause Autosomal-Recessive Severe Infantile Encephalopathy.	NALCN UNC79	5.83e-05	3	154	2	26708753
Pubmed	Genetic variants in components of the NALCN-UNC80-UNC79 ion channel complex cause a broad clinical phenotype (NALCN channelopathies).	NALCN UNC79	5.83e-05	3	154	2	30167850
Pubmed	Transcription factors Ets1, Ets2, and Elf1 exhibit differential localization in human endometrium across the menstrual cycle and alternate isoforms in cultured endometrial cells.	ETS2 ELF1	5.83e-05	3	154	2	10377039
Pubmed	Genetic analyses of the mouse deafness mutations varitint-waddler (Va) and jerker (Espnje).	CDH23 MCOLN3	5.83e-05	3	154	2	12209292
Pubmed	Cloning and characterization of rat BAT3 cDNA.	UBQLN1 BAG6	5.83e-05	3	154	2	10390159
Pubmed	Extracellular calcium controls background current and neuronal excitability via an UNC79-UNC80-NALCN cation channel complex.	NALCN UNC79	5.83e-05	3	154	2	21040849
Pubmed	Intellectual disability-associated UNC80 mutations reveal inter-subunit interaction and dendritic function of the NALCN channel complex.	NALCN UNC79	5.83e-05	3	154	2	32620897
Pubmed	Epigenetic profiling of cutaneous T-cell lymphoma: promoter hypermethylation of multiple tumor suppressor genes including BCL7a, PTPRG, and p73.	THBS4 PTPRG	5.83e-05	3	154	2	15897551
Pubmed	Functional validation of miRNAs targeting genes of DNA double-strand break repair to radiosensitize non-small lung cancer cells.	RAD51 PRKDC	5.83e-05	3	154	2	30389599
Pubmed	Direct interaction between hnRNP-M and CDC5L/PLRG1 proteins affects alternative splice site choice.	SMC1A HNRNPM HIP1R EDC4 TUBGCP4 RNF17 MDN1 XPO6 MACF1 PRKDC DNM2	6.11e-05	582	154	11	20467437
Pubmed	Cullin 1 (CUL1) Promotes Primary Ciliogenesis through the Induction of Ubiquitin-Proteasome-Dependent Dvl2 Degradation.	FLT3 ETS2 CDH23 ADGRV1 FAT2 MACF1	6.22e-05	152	154	6	34299191
Pubmed	Onecut-dependent Nkx6.2 transcription factor expression is required for proper formation and activity of spinal locomotor circuits.	ONECUT2 ONECUT1 ONECUT3	6.62e-05	18	154	3	31969659
Pubmed	Onecut1 and Onecut2 transcription factors operate downstream of Pax6 to regulate horizontal cell development.	ONECUT2 ONECUT1 ONECUT3	6.62e-05	18	154	3	25794677
Pubmed	A human MAP kinase interactome.	EXOSC9 HIVEP2 SUPT20H NEDD4L HNRNPM SPECC1L MADD MACF1 PRKDC SOS1	6.62e-05	486	154	10	20936779
Pubmed	Activity-based E3 ligase profiling uncovers an E3 ligase with esterification activity.	UBR1 NEDD4L RNF123 HERC3 HECTD1	6.70e-05	95	154	5	29643511
Pubmed	Functional proteomics mapping of a human signaling pathway.	UBQLN1 NEDD4L ETS2 LAMC1 PHKA2 RNF123 EIF4G2 MACF1 BAG6 ZMYM5 DNM2	7.00e-05	591	154	11	15231748
Pubmed	METTL3 protects METTL14 from STUB1-mediated degradation to maintain m6 A homeostasis.	UBR1 EXOSC9 LARP1B ARL8B PRKDC BAG6 SMG6	8.08e-05	231	154	7	36597993
Pubmed	Prediction of the coding sequences of mouse homologues of KIAA gene: II. The complete nucleotide sequences of 400 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.	NEDD4L MADD LRFN2 GPCPD1 MACF1 HERC3 SLC39A14 CAMTA1 SPATA13	8.97e-05	407	154	9	12693553
Pubmed	Proteomic analysis of the epidermal growth factor receptor (EGFR) interactome and post-translational modifications associated with receptor endocytosis in response to EGF and stress.	SMC1A SRPRA SCD EIF4G2 CTBP1 ATP2B1 DNM2 SOS1	1.02e-04	323	154	8	24797263
Pubmed	Onecut transcription factors act upstream of Isl1 to regulate spinal motoneuron diversification.	ONECUT2 ONECUT1 ONECUT3	1.07e-04	21	154	3	22833130
Pubmed	E3 ubiquitin ligase RNF123 targets lamin B1 and lamin-binding proteins.	TTC21A HNRNPM DNAH2 SRPRA DNAH14 SLC5A2 FREM2 RNF123 THBS4 MDN1 PLCB3 PRKDC	1.15e-04	736	154	12	29676528
Pubmed	Chromosomal localization of three human dual specificity phosphatase genes (DUSP4, DUSP6, and DUSP7).	DUSP4 DUSP7	1.16e-04	4	154	2	9205128
Pubmed	Engraftment of adult hematopoietic stem and progenitor cells in a novel model of humanized mice.	FLT3 PRKDC	1.16e-04	4	154	2	38433905
Pubmed	Astrocytic laminin-211 drives disseminated breast tumor cell dormancy in brain.	LAMC1 PRKDC	1.16e-04	4	154	2	35121993
Pubmed	Role for a novel Usher protein complex in hair cell synaptic maturation.	CDH23 ADGRV1	1.16e-04	4	154	2	22363448
Pubmed	Functional interaction of BRCA1/ATM-associated BAAT1 with the DNA-PK catalytic subunit.	SMC1A PRKDC	1.16e-04	4	154	2	22977523
Pubmed	Haplotype diversity in four genes (CLCNKA, CLCNKB, BSND, NEDD4L) involved in renal salt reabsorption.	NEDD4L CLCNKB	1.16e-04	4	154	2	17652939
Pubmed	Interaction of protocadherin-15 with the scaffold protein whirlin supports its anchoring of hair-bundle lateral links in cochlear hair cells.	CDH23 ADGRV1	1.16e-04	4	154	2	33009420
Pubmed	Novel small GTPase subfamily capable of associating with tubulin is required for chromosome segregation.	ARL8A ARL8B	1.16e-04	4	154	2	15331635
Pubmed	MuLV-related endogenous retroviral elements and Flt3 participate in aberrant end-joining events that promote B-cell leukemogenesis.	FLT3 PRKDC	1.16e-04	4	154	2	24888589
Pubmed	Grb2 dominantly associates with dynamin II in human hepatocellular carcinoma HepG2 cells.	DNM2 SOS1	1.16e-04	4	154	2	11746524
Pubmed	Expression of the alpha7 isoform of hepatocyte nuclear factor (HNF) 4 is activated by HNF6/OC-2 and HNF1 and repressed by HNF4alpha1 in the liver.	ONECUT2 ONECUT1	1.16e-04	4	154	2	15159395
Pubmed	Acute Myeloid Leukemia Alters Group 1 Innate Lymphoid Cell Differentiation from a Common Precursor.	FLT3 PRKDC	1.16e-04	4	154	2	34417259
Pubmed	Identification of Filamin A as a BRCA1-interacting protein required for efficient DNA repair.	RAD51 PRKDC	1.16e-04	4	154	2	20305393
Pubmed	Binding of microtubule-associated protein 1B to LIS1 affects the interaction between dynein and LIS1.	MAP1B DNAH8	1.16e-04	4	154	2	15762842
Pubmed	The NALCN channel complex is voltage sensitive and directly modulated by extracellular calcium.	NALCN UNC79	1.16e-04	4	154	2	32494638
Pubmed	The RNA-mediated estrogen receptor α interactome of hormone-dependent human breast cancer cell nuclei.	EXOSC9 GGNBP2 SUPT20H UBQLN1 HIP1R SRPRA SPECC1L EDC4 MYEF2 EFR3A MDN1 SCD EIF4G2 RBM5 MACF1 CTBP1 EDRF1 SMG6	1.19e-04	1497	154	18	31527615
Pubmed	Role of the Onecut transcription factors in pancreas morphogenesis and in pancreatic and enteric endocrine differentiation.	ONECUT2 ONECUT1 ONECUT3	1.23e-04	22	154	3	17400205
Pubmed	A dual-activity topoisomerase complex regulates mRNA translation and turnover.	RAD51 RAPGEF6 HIVEP2 HIP1R SLCO4A1 EDC4 NPHP4 ATP13A2 MADD MDN1 XPO6 PRKDC HECTD1 SPATA13 SMG6	1.24e-04	1105	154	15	35748872
Pubmed	TNF-α inhibits glucocorticoid receptor-induced gene expression by reshaping the GR nuclear cofactor profile.	GGNBP2 CTNNAL1 DNAH2 LAMC1 ARL8A MYEF2 RNF123 PTPN9 MDN1 ATP2B1 DNM2	1.37e-04	638	154	11	31182584
Pubmed	A Compendium of RNA-Binding Proteins that Regulate MicroRNA Biogenesis.	RBM12B HNRNPM EDC4 MYEF2 CELF2 RTCA RBM5	1.46e-04	254	154	7	28431233
Pubmed	Violating the splicing rules: TG dinucleotides function as alternative 3' splice sites in U2-dependent introns.	RAD51 CDH23 NPHP4 BAG6	1.80e-04	63	154	4	17672918
Pubmed	Defining the proximal interaction networks of Arf GTPases reveals a mechanism for the regulation of PLD1 and PI4KB.	STON1 TRPM7 HNRNPM SRPRA ARL8A SPECC1L UTP18 ARL8B RBM5 CTBP1 PRKDC SLC39A14	1.89e-04	777	154	12	35844135
Pubmed	Polymorphisms of DNA repair genes and risk of glioma.	RAD51 PRKDC	1.93e-04	5	154	2	15313891
Pubmed	The Histone Chaperones ASF1 and CAF-1 Promote MMS22L-TONSL-Mediated Rad51 Loading onto ssDNA during Homologous Recombination in Human Cells.	RAD51 PRKDC	1.93e-04	5	154	2	29478807
Pubmed	Molecular identification and characterization of novel members of the human organic anion transporter (OATP) family.	SLCO4A1 SLCO1A2	1.93e-04	5	154	2	10873595
Pubmed	Selective expansion of myeloid and NK cells in humanized mice yields human-like vaccine responses.	FLT3 PRKDC	1.93e-04	5	154	2	30487575
Pubmed	The TRPM7 channel is inactivated by PIP(2) hydrolysis.	TRPM7 PLCB3	1.93e-04	5	154	2	11941371
Pubmed	MiR-495 and miR-218 regulate the expression of the Onecut transcription factors HNF-6 and OC-2.	ONECUT2 ONECUT1	1.93e-04	5	154	2	19913497
Pubmed	Artemis and nonhomologous end joining-independent influence of DNA-dependent protein kinase catalytic subunit on chromosome stability.	SMC1A PRKDC	1.93e-04	5	154	2	19015239
Pubmed	Autoubiquitination of the 26S proteasome on Rpn13 regulates breakdown of ubiquitin conjugates.	UBR1 UBQLN1 HECTD1 BAG6	2.15e-04	66	154	4	24811749
Pubmed	Systematic proteomics of endogenous human cohesin reveals an interaction with diverse splicing factors and RNA-binding proteins required for mitotic progression.	SMC1A HNRNPM HIP1R MDN1 RBM5 PRKDC DNM2	2.21e-04	272	154	7	31010829
Pubmed	NDFIP allows NEDD4/NEDD4L-induced AQP2 ubiquitination and degradation.	SUPT20H NEDD4L SLC5A2	2.30e-04	27	154	3	28931009
Pubmed	Interaction between the scaffold proteins CBP by IQGAP1 provides an interface between gene expression and cytoskeletal activity.	HIVEP2 MAP1B EIF4G2 RBM5	2.56e-04	69	154	4	32238831
Pubmed	An organelle-specific protein landscape identifies novel diseases and molecular mechanisms.	EXOSC9 PATZ1 SMC1A TTC21A EXOC3 CDH23 TUBGCP4 NPHP4 PTPRG ARL8B XPO6 SCD CTBP1 BBS12 EDRF1 DNM2	2.68e-04	1321	154	16	27173435
Pubmed	EVI1 oncoprotein interacts with a large and complex network of proteins and integrates signals through protein phosphorylation.	SMC1A CTBP1 PRKDC CCDC180 BAG6	2.72e-04	128	154	5	23858473
Pubmed	Otx2 and Onecut1 promote the fates of cone photoreceptors and horizontal cells and repress rod photoreceptors.	ONECUT2 ONECUT1	2.89e-04	6	154	2	23867227
Pubmed	Opposing functions of the ETS factor family define Shh spatial expression in limb buds and underlie polydactyly.	ETS2 ELF1	2.89e-04	6	154	2	22340503
Pubmed	The Onecut transcription factor HNF-6 (OC-1) is required for timely specification of the pancreas and acts upstream of Pdx-1 in the specification cascade.	ONECUT2 ONECUT1	2.89e-04	6	154	2	12781686
Pubmed	Genome-wide association study does not reveal major genetic determinants for anti-cytomegalovirus antibody response.	FREM2 AGBL1	2.89e-04	6	154	2	21993531
Pubmed	Frem3, a member of the 12 CSPG repeats-containing extracellular matrix protein family, is a basement membrane protein with tissue distribution patterns distinct from those of Fras1, Frem2, and QBRICK/Frem1.	LAMC1 FREM2	2.89e-04	6	154	2	17462874
Pubmed	Enhancer recruitment of transcription repressors RUNX1 and TLE3 by mis-expressed FOXC1 blocks differentiation in acute myeloid leukemia.	SMC1A HNRNPM ELF1 CTBP1 PRKDC	3.03e-04	131	154	5	34551306
Pubmed	LMBR1L regulates lymphopoiesis through Wnt/β-catenin signaling.	UBQLN1 SLC43A1 HNRNPM DNAH2 SRPRA EDC4 RINT1 XPO6 HS2ST1 EIF4G2 PRKDC HECTD1 BAG6	3.04e-04	942	154	13	31073040
Pubmed	BioID-based intact cell interactome of the Kv1.3 potassium channel identifies a Kv1.3-STAT3-p53 cellular signaling pathway.	CTNNAL1 MAP1B SMC1A HNRNPM EXOC3 SRPRA EFR3A EIF4G2 MACF1 PRKDC ATP2B1	3.34e-04	708	154	11	39231216
Interaction	NXPH2 interactions	UBR1 ADGRV1 ITIH2 MADD FREM2	4.15e-06	33	149	5	int:NXPH2
Cytoband	5q13	MAP1B ADGRV1 THBS4	5.44e-05	22	154	3	5q13
Cytoband	Ensembl 112 genes in cytogenetic band chr11q11	OR4C15 OR4A8 OR4A5	3.34e-04	40	154	3	chr11q11
Cytoband	1p36	NPHP4 ATP13A2 CLCNKB	5.39e-04	47	154	3	1p36
GeneFamily	Dyneins, axonemal	DNAH2 DNAH14 DNAH1 DNAH8	3.01e-06	17	111	4	536
GeneFamily	CUT class homeoboxes and pseudogenes	ONECUT2 ONECUT1 ONECUT3	1.84e-05	9	111	3	527
GeneFamily	Ubiquilin family	UBQLN1 UBQLN3	3.69e-04	5	111	2	783
GeneFamily	Schlafen family	SLFN12 SLFNL1	7.69e-04	7	111	2	1110
GeneFamily	MAP kinase phosphatases	DUSP4 DUSP7	1.98e-03	11	111	2	895
Coexpression	MANNO_MIDBRAIN_NEUROTYPES_HGABA	GPR155 RAPGEF6 TRIM2 NEDD4L MAP1B DUSP4 ETS2 ARL8A LARP1B GABBR2 FAT2 MDN1 CELF2 NALCN NCOA7 CAMTA1 ATP2B1 UNC79 SPATA13	2.11e-05	1106	151	19	M39071
Coexpression	GSE18893_CTRL_VS_TNF_TREATED_TREG_24H_DN	SMC1A SLFN12 ALS2CL PCBD2 TREML4 NCOA7 PAM ZMYM5	2.18e-05	200	151	8	M7296
Coexpression	GSE8835_CD4_VS_CD8_TCELL_UP	SUPT20H SLCO4A1 PHKA2 CELF2 HS2ST1 PRKDC ATP2B1 SMG6	2.18e-05	200	151	8	M6254
ToppCell	COPD-Epithelial-ATII\|Epithelial / Disease state, Lineage and Cell class	HIVEP2 NEDD4L FREM2 PTPRG CELF2 SCD SCTR AGBL1	2.98e-07	187	154	8	030af361f8bdcd0aff4ec1922702833325cf74d8
ToppCell	COVID-19-lung-AT2\|lung / Disease (COVID-19 only), tissue and cell type	NEDD4L TMEM63B ADGRV1 DNAH14 FREM2 SCD SCTR AGBL1	3.50e-07	191	154	8	276455a64c2c3503d5048615762eb2ee37f0ac70
ToppCell	TCGA-Endometrium-Primary_Tumor-Endometrial_Adenocarcinoma-Endometrioid-1\|TCGA-Endometrium / Sample_Type by Project: Shred V9	UBQLN1 SMC1A TUBGCP4 FREM2 PTPN9 SCD HS2ST1 EIF4G2	3.79e-07	193	154	8	c2673d86f7d7b849788036032a93a6d136a70040
ToppCell	Primary_Visual_cortex_(V1C)-Neuronal\|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	HIVEP2 MAP1B EML6 GABBR2 CELF2 PAM ATP2B1 UNC79	4.60e-07	198	154	8	8ab40fae14fe02e39bc8c8da187a5cd60c787643
ToppCell	CD8+_Memory_T_cell-CV-7\|CD8+_Memory_T_cell / cell class, Virus stimulation and cluster	UBR1 TRPM7 CELF2 GPCPD1 MACF1 PRKDC EDRF1	4.67e-06	191	154	7	9454f642c3621370fa23640b631301346b300950
ToppCell	Adult-Epithelial-alveolar_epithelial_cell_type_2-D122\|Adult / Lineage, Cell type, age group and donor	NEDD4L ADGRV1 DNAH14 FREM2 PTPRG SCTR AGBL1	4.83e-06	192	154	7	06013a07e3a873b1d1c0451643c528593ac32a9c
ToppCell	Somatosensory_Cortex_(S1)-Neuronal\|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	HIVEP2 MAP1B RAPGEF4 GABBR2 PAM ATP2B1 UNC79	5.91e-06	198	154	7	c01091ef18e096d792ea2a7a715764a5b215355f
ToppCell	primary_auditory_cortex_(A1C)-Neuronal\|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	MAP1B EML6 RAPGEF4 GABBR2 CELF2 ATP2B1 UNC79	5.91e-06	198	154	7	6d18b45eda4014759e6dd282d78ffd28df8a6044
ToppCell	Primary_Motor_Cortex_(M1)-Neuronal\|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	MAP1B EML6 RAPGEF4 GABBR2 CELF2 ATP2B1 UNC79	5.91e-06	198	154	7	4ca5ff320905ab4ff60ed90a5522227c782142a6
ToppCell	Neuronal\|World / cells hierarchy compared to all cells using T-Statistic	MAP1B EML6 RAPGEF4 GABBR2 CELF2 ATP2B1 UNC79	6.31e-06	200	154	7	48d801219bc771d6c7e151dc88ca4c179988de85
ToppCell	Children_(3_yrs)-Endothelial-endothelial_cell_of_bronchial_vessel-D139\|Children_(3_yrs) / Lineage, Cell type, age group and donor	ATP8B3 CTNNAL1 SMC1A TTC21A RAPGEF4 MADD	1.74e-05	156	154	6	ff39712c7a2dc1b85c598d5105789aa291dea726
ToppCell	facs-Kidney-nan-24m-Lymphocytic-B_cell\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ARMC3 NIBAN3 KPNA7 SCD GPCPD1 AGBL1	2.55e-05	167	154	6	3c4183a8225bae37b9f5341ebd1b95409ced2022
ToppCell	facs-Kidney-nan-24m-Lymphocytic-B_cell\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ARMC3 NIBAN3 KPNA7 SCD GPCPD1 AGBL1	2.55e-05	167	154	6	28e9670586ff551b700c794313d27eedbfa1286b
ToppCell	3'-GW_trimst-1-SmallIntestine-Epithelial-neuro-epithelial-L_cells_(PYY+)\|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	ABCA10 THBS4 PAM ONECUT3 UNC79 MCOLN3	2.64e-05	168	154	6	0f736d58cb0ff042fa3ce58e36bde37b6976f8fc
ToppCell	facs-Diaphragm-Limb_Muscle-24m\|Diaphragm / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	HIVEP2 ADGRV1 RNF17 DNAH1 NALCN UNC79	2.73e-05	169	154	6	12bdc709bc000d7f9061ecd9fbd57233eaacb7e2
ToppCell	TCGA-Colorectal-Primary_Tumor-Colorectal_Adenocarcinoma-Rectal_Adenocarcinoma-7\|TCGA-Colorectal / Sample_Type by Project: Shred V9	HIVEP2 RAPGEF4 FKBP9 LAMC1 ELF1 SPATA13	3.65e-05	178	154	6	edc76b8f15056ec1c9a1c61a048b6331a92592d6
ToppCell	Control-Epithelial_cells-AT2\|Control / group, cell type (main and fine annotations)	NEDD4L ADGRV1 FREM2 PTPRG SCTR AGBL1	3.88e-05	180	154	6	198b19e7910b4a8cc7e820c525ab357c7f99f578
ToppCell	COPD-Epithelial-ATII\|World / Disease state, Lineage and Cell class	NEDD4L ADGRV1 FREM2 PTPRG SCTR AGBL1	4.25e-05	183	154	6	8e9aab4eeec2e282c2cab9bfca6dbf40d660c7b9
ToppCell	3'-Adult-LargeIntestine-Epithelial-neuro-epithelial-L_cells_(PYY+)\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	EML6 SCTR PAM BBS12 MCOLN3 SPATA13	4.25e-05	183	154	6	49f3ddc1c7c04b4ca837dbd6dad995add82941d6
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic-thymocyte\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ONECUT2 ADGRV1 DNAH1 FREM2 ONECUT3 UNC79	4.39e-05	184	154	6	2cbed6462fea2622871bb7e49b0df3d984239281
ToppCell	COVID-19-Epithelial_cells-AT2\|COVID-19 / group, cell type (main and fine annotations)	NEDD4L ADGRV1 FREM2 SCD SCTR AGBL1	4.39e-05	184	154	6	369b82f793deab672204558ae4e112cfa5aa9ccc
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ONECUT2 ADGRV1 DNAH1 FREM2 ONECUT3 UNC79	4.39e-05	184	154	6	ea7a7e2bac46d4d2c31a5d576b38a032b5335062
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic-proliferating_thymocyte;_DN_to_DP_transition,_dividing_(some_are_Cd8+/_Cd4+,_some_undergoing_VDJ_recombination)\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ONECUT2 ADGRV1 DNAH1 FREM2 ONECUT3 UNC79	4.39e-05	184	154	6	2b19a8c5f823e00812908b23e66bb4e563278aff
ToppCell	3'-GW_trimst-1.5-SmallIntestine-Neuronal-neurons_B-Branch_B3_(IPAN)\|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	MAP1B DUSP4 RAPGEF4 HIP1R MYEF2 PLCB3	4.52e-05	185	154	6	edb114487206e4e8df4c7878285df40f49b7fd64
ToppCell	COPD-Epithelial-ATII\|COPD / Disease state, Lineage and Cell class	NEDD4L ADGRV1 FREM2 PTPRG SCTR AGBL1	4.94e-05	188	154	6	eb6d79d733b53f64ca615bb777c64ed456866549
ToppCell	PBMC-Mild-cDC_12\|Mild / Compartment, Disease Groups and Clusters	RAD51 CTNNAL1 HIP1R NALCN PRKDC SLC39A14	5.09e-05	189	154	6	946c95d2ecc36b241f58e8c4ad6455fe47c762fa
ToppCell	COVID-19-lung-AT2\|COVID-19 / Disease (COVID-19 only), tissue and cell type	NEDD4L TMEM63B ADGRV1 SCD SCTR AGBL1	5.24e-05	190	154	6	27a1a86620fe9b5ee930d388b32352206485e6d0
ToppCell	PND10\|World / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	MAP1B NIBAN3 EIF4G2 PAM MACF1 ATP2B1	5.24e-05	190	154	6	d67e2814047c8df2ae4b7bc8be9539f5df6ecef2
ToppCell	Children_(3_yrs)-Epithelial-alveolar_epithelial_cell_type_2\|Children_(3_yrs) / Lineage, Cell type, age group and donor	NEDD4L ADGRV1 FREM2 PTPRG SCTR AGBL1	5.40e-05	191	154	6	a0332a4ef629510fb313ec119195c44a3f704a80
ToppCell	Fetal_29-31_weeks-Epithelial-alveolar_epithelial_cell_type_1/2_(AT1/AT2-like)\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	NEDD4L TMEM63B ADGRV1 DNAH14 FREM2 AGBL1	5.40e-05	191	154	6	ca5669bd6f4a17471acae3eb229f845cc2e08efa
ToppCell	Epithelial-alveolar_epithelial_cell_type_2\|World / Lineage, Cell type, age group and donor	NEDD4L ADGRV1 FREM2 PTPRG SCTR AGBL1	5.55e-05	192	154	6	58c3737be7acce39fd2b91d70d6d7b2bbaa4f710
ToppCell	Fetal_29-31_weeks-Epithelial-alveolar_epithelial_cell_type_2\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	NEDD4L ADGRV1 DNAH14 FREM2 SCTR AGBL1	5.55e-05	192	154	6	fb2f0e897228f808d9ff734ad05e9b49dc38fa50
ToppCell	nucseq-Epithelial-Epithelial_Alveolar-AT2-AT2\|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	NEDD4L ADGRV1 FREM2 PTPRG SCTR NCOA7	5.72e-05	193	154	6	fd4d3c0d7caf8a2fff5b3d901fc28d19a8163cdf
ToppCell	nucseq-Epithelial-Epithelial_Alveolar-AT2\|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	NEDD4L ADGRV1 FREM2 PTPRG SCTR NCOA7	5.72e-05	193	154	6	f3cc7cfdbc164a4ed42f87647111522b7d393bcb
ToppCell	nucseq-Epithelial-Epithelial_Alveolar\|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	NEDD4L ADGRV1 DNAH14 FREM2 NCOA7 PAM	5.88e-05	194	154	6	53f3e49e91b1096f3226010e2de767efb490dfe4
ToppCell	Primary_Visual_cortex_(V1C)-Neuronal-Glutamatergic_Excit\|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	HIVEP2 NEDD4L MAP1B GABBR2 CELF2 ATP2B1	6.05e-05	195	154	6	2e1df01bf6e4e98e6cd9fb50926e34c5077b8666
ToppCell	Mid-temporal_gyrus_(MTG)-Neuronal\|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	MAP1B EML6 RAPGEF4 GABBR2 ATP2B1 UNC79	6.23e-05	196	154	6	676c56b44ac29f7baecb62f49bb8597cc74c0a88
ToppCell	10x_3'_v2v3-Neoplastic-Differentiated-like-MES-like-MES-like_hypoxia_independent-F\|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	CCNL2 MAP1B LAMC1 FREM2 PAM SLC39A14	6.23e-05	196	154	6	b8b9801181d7604871b48aebacb295d0a57a5eaf
ToppCell	10x_3'_v3-tissue-resident_(10x_3'_v3)-myeloid-myeloid_monocytic-leukocyte\|tissue-resident_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type	DSG3 TNFSF9 DUSP4 RAPGEF4 ELF1 IL26	6.40e-05	197	154	6	d968d7d5608b175bb567ea3a315bf473ec3be459
ToppCell	Bronchial-NucSeq-Epithelial-Epi_alveolar-AT2\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	NEDD4L ADGRV1 FREM2 PTPRG SCTR AGBL1	6.59e-05	198	154	6	f948391296c261c473d339069a6d0f20ccd6f38f
ToppCell	Parenchymal-NucSeq-Epithelial-Epi_alveolar-AT2\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	NEDD4L ADGRV1 FREM2 PTPRG SCTR AGBL1	6.59e-05	198	154	6	2e2a4e1756bba6f4fbe529559a97d2993c890b4b
ToppCell	Neuron-Postmitotic-Excitatory_Neuron_-Layer_IV-2\|World / Primary Cells by Cluster	TRIM2 HIVEP2 MAP1B GABBR2 CELF2 ATP2B1	6.77e-05	199	154	6	f09b40245d3d826275bbe5f508dedccc75a911bd
ToppCell	Bronchial-NucSeq-Epithelial-Epi_alveolar\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	NEDD4L ADGRV1 DNAH14 FREM2 SCTR AGBL1	6.77e-05	199	154	6	725610310e5c5fd7120c0be9acb55bf152026ddd
ToppCell	Neuron-Postmitotic-Excitatory_Neuron_-Layer_IV\|World / Primary Cells by Cluster	TRIM2 HIVEP2 MAP1B GABBR2 CELF2 ATP2B1	6.77e-05	199	154	6	e45448ec4db8875c8aaa9aad109a10e2905a4226
ToppCell	COVID-19-COVID-19_Convalescent-Lymphocyte-B-B_memory\|COVID-19_Convalescent / Disease, condition lineage and cell class	TTC21A EML6 PPM1K NIBAN3 DNAH8 ATP2B1	6.77e-05	199	154	6	5bbda86486910d053ca51b9caee487d78f6462cb
ToppCell	Tracheal-NucSeq-Endothelial-Endothelia_vascular-VE_pulmonary_venous\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	ARMC3 ETS2 SLCO4A1 CDH23 ONECUT3 BAG6	6.77e-05	199	154	6	079931e7196719f22a89cfad82f452ec67219ee5
ToppCell	LPS_IL1RA_TNF-Epithelial_airway-airway_epithelial-Ciliated\|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type	ARMC3 TTC21A EML6 DNAH2 DNAH1 CCDC180	6.96e-05	200	154	6	96701a4d57753f5ec0dd5c7550054bbcc946bc5f
ToppCell	Neuronal-Excitatory-eA(LAMP5_LINC00507)-GLP2R--\|Neuronal / cells hierarchy compared to all cells using T-Statistic	ONECUT2 DSG3 EML6 ADGRV1 PAM ATP2B1	6.96e-05	200	154	6	dc8702e3cb4ac8c1a9849fc8abf8777f12d55b0b
ToppCell	Neuronal-Excitatory-eA(LAMP5_LINC00507)-GLP2R---L2-4\|Neuronal / cells hierarchy compared to all cells using T-Statistic	ONECUT2 DSG3 EML6 ADGRV1 PAM ATP2B1	6.96e-05	200	154	6	d92d51021ab6d78e9c8f89f7c150181004dcbcbd
ToppCell	Neuronal-Excitatory-eA(LAMP5_LINC00507)-GLP2R-\|Neuronal / cells hierarchy compared to all cells using T-Statistic	ONECUT2 DSG3 EML6 ADGRV1 PAM ATP2B1	6.96e-05	200	154	6	cbbb9044283ff9ab63bbfc24d7a9f006b1372705
ToppCell	Control_saline-Endothelial-Endothelial-Gen_Cap\|Control_saline / Treatment groups by lineage, cell group, cell type	CTNNAL1 RAPGEF4 ETS2 PTPRG GPCPD1 MACF1	6.96e-05	200	154	6	3b97920e1e6e2f09ddba2a861baa9c00c2970f4c
ToppCell	Brain_organoid-organoid_Tanaka_cellReport-2m-Neuronal-Intermediate\|2m / Sample Type, Dataset, Time_group, and Cell type.	TRIM2 NEDD4L MAP1B CELF2 HECTD1 ATP2B1	6.96e-05	200	154	6	2a635694844ddabcd98462c5636a6f41a3f08a46
ToppCell	Neuronal-Excitatory-eA(LAMP5_LINC00507)-GLP2R\|Neuronal / cells hierarchy compared to all cells using T-Statistic	ONECUT2 DSG3 EML6 ADGRV1 PAM ATP2B1	6.96e-05	200	154	6	a3e36bbeed19431d07bc205f14f4e0f12bd8f730
ToppCell	LPS-antiTNF-Myeloid-Dendritic_cells-pDC\|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	FLT3 CDH23 ATP13A2 NIBAN3 LRFN2	8.61e-05	129	154	5	454bae525f6db3d0dd6347d2a2c3ea9dda9cd212
Disease	response to radiation, Urinary retention	AGMO CAMTA1 DNM2	8.31e-05	17	150	3	GO_0009314, HP_0000016
Disease	Disorder of eye	CDH23 ADGRV1 NPHP4 ATP13A2 RLBP1 FREM2 BBS12	1.11e-04	212	150	7	C0015397
Disease	Ciliopathies	CDH23 ADGRV1 NPHP4 DNAH8 BBS12	2.53e-04	110	150	5	C4277690
Disease	post-operative atrial fibrillation, response to surgery	STON1 ADGRV1	2.54e-04	5	150	2	EFO_0009951, EFO_0009952
Disease	Ischemic stroke	STON1 RNF17 PTPRG AGMO HTR3B AGBL1 ATP2B1 DNM2	2.65e-04	324	150	8	HP_0002140
Disease	Drugs used in diabetes use measurement	HIVEP2 LRFN2 AGMO SCTR PAM MACF1 CTBP1	3.42e-04	255	150	7	EFO_0009924
Disease	heel bone mineral density, urate measurement	EML6 FKBP9 DNAH14 AGMO NCOA7 TMEM50B	3.48e-04	182	150	6	EFO_0004531, EFO_0009270
Disease	periventricular nodular heterotopia (is_implicated_in)	NEDD4L MAP1B	3.80e-04	6	150	2	DOID:0050454 (is_implicated_in)
Disease	amyotrophic lateral sclerosis (implicated_via_orthology)	UBQLN1 ALS2CL ATP13A2	4.73e-04	30	150	3	DOID:332 (implicated_via_orthology)
Disease	Epileptic encephalopathy	NEDD4L SMC1A GABBR2	4.73e-04	30	150	3	C0543888
Disease	Periventricular Nodular Heterotopia	NEDD4L MAP1B	5.30e-04	7	150	2	C1868720
Disease	pit and fissure surface dental caries	HIVEP2 EFR3A OC90	7.48e-04	35	150	3	EFO_0006338
Disease	corticobasal degeneration disorder	DUSP4 SOS1	9.03e-04	9	150	2	MONDO_0022308
Disease	nephronophthisis (implicated_via_orthology)	TTC21A NPHP4	9.03e-04	9	150	2	DOID:12712 (implicated_via_orthology)
Disease	Fuchs endothelial corneal dystrophy	LAMC1 PTPRG	1.12e-03	10	150	2	Orphanet_98974
Disease	urate measurement, bone density	B3GNTL1 TNFSF9 ETS2 DNAH14 DNAH1 PCBD2 PTPRG EIF4G2 PRKDC DNAH8	1.30e-03	619	150	10	EFO_0003923, EFO_0004531
Disease	response to virus	FREM2 AGBL1	1.37e-03	11	150	2	GO_0009615
Disease	hemoglobin A1 measurement	GPR155 SLCO4A1 MADD PTPN9 AGMO MACF1 ELF1 PLCB3 SMG6	1.42e-03	520	150	9	EFO_0007629
Disease	Manganese Poisoning	ATP13A2 SLC39A14	2.24e-03	14	150	2	C0677050
Disease	aspartate aminotransferase measurement	ONECUT2 RAPGEF6 B3GNTL1 STON1 NEDD4L TRPM7 DNAH2 MADD CELF2 ELF1 SMG6 SOS1	2.31e-03	904	150	12	EFO_0004736
Disease	migraine disorder	ONECUT2 NEDD4L MACF1 CAMTA1 AGBL1 ATP2B1 SMG6	2.41e-03	357	150	7	MONDO_0005277
Disease	aspartate aminotransferase measurement, serum alanine aminotransferase measurement, low density lipoprotein triglyceride measurement, body fat percentage, high density lipoprotein cholesterol measurement, sex hormone-binding globulin measurement	GGNBP2 ONECUT1 LRFN2 PTPRG MACF1 CAMTA1 UNC79	2.68e-03	364	150	7	EFO_0004612, EFO_0004696, EFO_0004735, EFO_0004736, EFO_0007800, EFO_0009946
Disease	Colorectal Carcinoma	MAP1B TRPM7 LAMC1 ABCA10 MLH3 SLCO1A2 CTBP1 DNAH8 EDRF1 NLRP8	3.24e-03	702	150	10	C0009402
Disease	apolipoprotein A 1 measurement	FLT3 TRIM2 STON1 HNRNPM HIP1R LAMC1 MADD XPO6 MACF1 PLCB3 SMG6	4.16e-03	848	150	11	EFO_0004614
Disease	cystatin C measurement	FLT3 HIVEP2 CST9 ADGRV1 DNAH1 RNF123 SOS1	4.61e-03	402	150	7	EFO_0004617

Protein segments in the cluster

Peptide	Gene	Start	Entry
ISENRIIGAMAIFFQ	PTPRG	191	P23470
VVNAVTLFGNLQSFM	ALS2CL	186	Q60I27
VIQEQAAALGLAMFS	SMG6	966	Q86US8
FGTNSDVLAQQFALM	DCAF4	321	Q8WV16
SAQAAIQAMNGFQIG	CELF2	476	O95319
QFQANFQAMTAEGEV	CAMTA1	676	Q9Y6Y1
MAAVVQQNDLVFEFA	ELF1	1	P32519
FMQAGFRKAIQQIES	ANTXRL	151	A6NF34
LINDFTVKQMRQGAF	CTBP1	246	Q13363
SNALMGIFNFTELIQ	ABCA10	901	Q8WWZ4
AFLQGMTDFLQATQT	BAG6	641	P46379
AQQDVSVSQGFRMLF	AGMO	6	Q6ZNB7
SSAGGFAQIQFNVVM	HTR3B	221	O95264
SQVGFESTAFQLMNI	ADGRV1	4886	Q8WXG9
NFMLAFQAAESVGIK	SPECC1L	1071	Q69YQ0
VQGFVMNFSNGEIID	PAM	756	P19021
GMQAVQNSDFVLGQF	ATP8B3	961	O60423
NATMIFGILASNNDV	ARMC3	86	Q5W041
TLVNQFFFQMVGALQ	CCDC180	476	Q9P1Z9
VMQAFAEAAGAVQVA	BBS12	441	Q6ZW61
VENIMAGATVLFLNA	CDH23	681	Q9H251
MFLATVEFALNTFNV	CST9	46	Q5W186
GIMALVAAYLNFVSQ	EFR3A	596	Q14156
FNTFVLMQLFNEINA	ATP2B1	976	P20020
FLAAQGMEILFSTTQ	AGBL1	231	Q96MI9
SEAQIQEFGVNFSVM	RBM12B	476	Q8IXT5
SFLVLTTDGINFMVN	PPM1K	291	Q8N3J5
MAVGFFQRGVANFQL	NOXA1	71	Q86UR1
TNQVVAQVDGAAMFA	RAD51	266	Q06609
NQAFGFMSRVALQAE	PCBD2	71	Q9H0N5
QAMFQQINDSFRLGT	EDC4	1131	Q6P2E9
FGFLTVTNLGVENMN	PTPN9	426	P43378
MQSLVFGAQDLAQQL	NIBAN3	461	Q86XR2
LAQQLMADAVATFLQ	NIBAN3	471	Q86XR2
YSMAAQFVLDGLTQQ	OR8D1	6	Q8WZ84
QVKFNVFQGIMDSLF	MLX	236	Q9UH92
FVNVIASGQFSEDMI	ARL8B	36	Q9NVJ2
FVNVIASGQFNEDMI	ARL8A	36	Q96BM9
VFSQQIFMGEIEENS	DSG3	156	P32926
MQNQSFVTEFVLLGL	OR4C15	1	Q8NGM1
VANFATGATMDQLIQ	KPNA7	391	A9QM74
FLESVANMFAAAQQL	MDN1	5466	Q9NU22
VAMVRFFNSANVLQG	MADD	491	Q8WXG6
DSALFAVNGFNMLIN	MAP1B	271	P46821
NIQDNISLFSLGMGF	ITIH2	441	P19823
QLVLFGLSNQMVVAF	MCOLN3	76	Q8TDD5
IFISQDEIQSFMANN	GGNBP2	641	Q9H3C7
GDQVLSFAMENTILF	NLRP8	376	Q86W28
EIGVFYMNQAAALQS	EDRF1	846	Q3B7T1
APGVAIFATQFNMEV	GPR155	326	Q7Z3F1
VAVNGANLQNVFMLL	HERC3	676	Q15034
FENITLGMNFTQDEV	FREM2	1361	Q5SZK8
EAVQAISMFNGQLLF	HNRNPM	256	P52272
QQDEMLNLGFTIGSF	SLC43A1	71	O75387
ATEGILFFNLELSQM	EXOSC9	71	Q06265
GLAAFSINQDTGMIQ	FAT2	1076	Q9NYQ8
NMETFQVQVIDNGFG	MLH3	46	Q9UHC1
VDQMFQFASIDVAGN	MYL5	141	Q02045
EFSLVNVNLQRFGMN	ETS2	121	P15036
LEVQIQAFMNSSFGK	DNAH8	436	Q96JB1
QLGLELSTVSNFFMN	ONECUT1	421	Q9UBC0
QQLGLELTTVSNFFM	ONECUT2	461	O95948
SFTADQLQVMQAQFA	LHX8	231	Q68G74
ILFVGESVQMFENQN	TUBGCP4	276	Q9UGJ1
VFITQLLGTVNFENM	OVOS2	321	Q6IE36
NINITFFSGMFKNVE	OC90	36	Q02509
TKALLQMVQQFGVDF	DNM2	326	P50570
GIATSDNFMQAFLNV	EIF4G2	611	P78344
QQNRGFAFVQLSSAM	RBM5	271	P52756
QTLSNEIIMFVAGFL	PLBD1	91	Q6P4A8
ALASTQQFQQMFDEL	MACF1	4796	Q9UPN3
LFSGQFMDALQALVD	MACF1	6661	Q9UPN3
NEMVLQFLAFSRVAQ	NPHP4	641	O75161
GLSLAAMQNVFDTNF	RDH8	101	Q9NYR8
QNMSLLESFGFQIVQ	PATZ1	651	Q9HBE1
DPVNTVFLNFMAVQD	PLCB3	111	Q01970
FQTLDVAMQLNAGVF	PLCB3	676	Q01970
GFDAELIVKNMFTNQ	FKBP9	531	O95302
VFSAMIFGTITNQDL	FLT3	16	P36888
QYMLNNISGDVLVAA	DNAH1	3141	Q9P2D7
LNFVGAFMLESVLDQ	ATP13A2	1126	Q9NQ11
GTDVNNIFQLTVEMF	HIP1R	166	O75146
AFEVNFMDDVGQTLL	HECTD1	386	Q9ULT8
AMSFAQFENLLGINV	GPCPD1	546	Q9NPB8
NQEMSLLQVFLSEAF	KLRG1	116	Q96E93
VQIFSQFGNEMVEFA	CTNNAL1	191	Q9UBT7
VDFLFSMAANQVFQN	GLT6D1	166	Q7Z4J2
SMAANQVFQNEFGVE	GLT6D1	171	Q7Z4J2
QVAMATGQVLFQRFF	CCNL2	96	Q96S94
MAFFSRLNLQEGLQT	DGAT2L6	1	Q6ZPD8
NYVIASAFIGNAMDL	TMEM63B	571	Q5T3F8
LSFFMEDVFGQLQLQ	IL26	86	Q9NPH9
NFNFMGQLLDFERTL	DUSP7	371	Q16829
FVTMINFTVTFQGLQ	DNAH14	2601	Q0VDD8
GRIILNAMNETNFFG	GABBR2	396	O75899
NAMNETNFFGVTGQV	GABBR2	401	O75899
MPEFVNAAFNVTVVA	LAMC1	51	P11047
QTMLSVAFGANNLTF	EML6	1556	Q6ZMW3
QSNLEEFQEAIMAFL	FAM186A	666	A6NE01
AIVFQMFEQNLQVAA	EXOC3	426	O60645
FSFMGQLLQFESQVL	DUSP4	321	Q13115
AQRASILFFVLNDMG	DNAH2	3611	Q9P225
AGMSIQQALFFNFLS	SLC39A14	391	Q15043
LGIGQSQEMNTLFRF	LARP1B	726	Q659C4
ASQLFLQDQVSIGAM	PHKA2	1171	P46019
MSNQTLVTEFILQGF	OR13A1	21	Q8NGR1
LGLELNTVSNFFMNA	ONECUT3	451	O60422
ALFQGLSNIAFNCMV	ABCB8	376	Q9NUT2
MRQNNNITEFVLLGF	OR4A5	1	Q8NH83
MRQNNNITEFVLLGF	OR4A8	1	P0C604
VMVAGLDNAVSLFQV	UTP18	266	Q9Y5J1
NSFFAIVMGLSNVAV	RAPGEF4	861	Q8WZA2
VNGQNFENITFMKAV	RAPGEF6	581	Q8TEU7
NFNSMFAIISGLNLA	RAPGEF6	946	Q8TEU7
AVQAISMFNGQFLFD	MYEF2	286	Q9P2K5
NSAVEMQVQSALAFL	NCOA7	456	Q8NI08
LQAVMLGDANITANF	PKDREJ	336	Q9NTG1
AVVAFAVAMLFLENQ	HS2ST1	16	Q7LGA3
QTGMLFVGDAVLQVN	SNTG2	111	Q9NY99
FILVSVIQFNAFVNM	SLCO1A2	321	P46721
NNFNGVLEVVSAMNS	SOS1	866	Q07889
QLFQGAFLGSETRNM	SLFNL1	211	Q499Z3
AAAFLQGMTVNGFIN	SLCO4A1	111	Q96BD0
LQQDFEGTMELSVFN	B3GNTL1	41	Q67FW5
QQVMGSLVKDFFAQQ	CIAO3	216	Q9H6Q4
GAFMFRLLAVFNSEQ	CLCNKB	246	P51801
ALIQIFMVDFGNSEV	RNF17	511	Q9BXT8
MFTVAQLATIFGNIE	SPATA13	276	Q96N96
TGDFNRQFLGQMTQL	THBS4	216	P35443
FFNITMIQLTQNDSG	TREML4	91	Q6UXN2
VQGAYVELQAFVNMA	STON1	536	Q9Y6Q2
NMAFDFILDNVQVVL	REV1	1226	Q9UBZ9
FNEGGAAQLQFDMTR	RINT1	696	Q6NUQ1
SVDMFSGAVFIQQAL	SLC5A2	156	P31639
FSEFIGMIQEIQQAA	RNF123	1041	Q5XPI4
RFQQQLEQLSAMGFL	UBQLN1	546	Q9UMX0
QDQLIVFMALANGVS	RTCA	296	O00442
MEIQLFFELALGSFQ	SCTR	366	P47872
QVMANSAGLNFINVV	SUPT20H	536	Q8NEM7
TLAFFMINAVSNAQV	TMEM50B	66	P56557
IARSQETNQMLFGFN	UBR1	1731	Q8IWV7
RNFLVFQGAVESIAM	SMC1A	131	Q14683
IQEENNMKALAGVFF	SLFN12	171	Q8IYM2
IAMEAIAFARNQGFD	SRPRA	501	P08240
LFLIIANTMAFQNDV	SCD	136	O00767
IENFKGFTMQQAASL	RLBP1	201	P12271
ANMEAALGSFIQIAQ	TTC21A	1141	Q8NDW8
MFAQLVAQNVLLIDG	TNFSF9	91	P41273
QLFQVMNGILAQDSA	PRKDC	3766	P78527
MQRAGLQNELFFAFS	ZPBP	221	Q9BS86
LNSLIQVFVMNVDFA	USP41	66	Q3LFD5
RMNVAGDLFQNGEFA	ZMYM5	176	Q9UJ78
QFSAIMQAFGQSFLQ	XPO6	976	Q96QU8
ALQNNFFITNLMDVL	TRIM2	76	Q9C040
NAAMQGIGFNIAQVL	HIVEP2	1381	P31629
FQVQLEQLRSMGFLN	UBQLN3	616	Q9H347
FGQNEALHLFQTLME	TRPM7	356	Q96QT4
FIAGIAQVMDYNINL	UNC79	1341	Q9P2D8
GNFIIHISRQDFANM	LRFN2	61	Q9ULH4
FNFDNVGNAMLALFE	NALCN	1096	Q8IZF0
FVNRVQKQMNAFLEG	NEDD4L	816	Q96PU5
QKQMNAFLEGFTELL	NEDD4L	821	Q96PU5