Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	calcium ion binding	SLIT2 FBLN1 THBS4 FBN1 SCUBE2 LRP2 LRP4 PAM PRRG4 LTBP1 RET PCDH8 F12 NOTCH1 C2CD5	1.19e-06	749	90	15	GO:0005509
GeneOntologyMolecularFunction	extracellular matrix structural constituent	SLIT2 FBLN1 THBS4 FBN1 VWF LAMC1 LTBP1 MUC5AC	2.13e-06	188	90	8	GO:0005201
GeneOntologyMolecularFunction	complement binding	CFH C4A C4B C8A	1.26e-05	32	90	4	GO:0001848
GeneOntologyMolecularFunction	opsonin binding	CFH C4A C4B	1.90e-04	25	90	3	GO:0001846
GeneOntologyMolecularFunction	laminin-1 binding	SLIT2 THBS4	5.53e-04	8	90	2	GO:0043237
GeneOntologyMolecularFunction	complement component C1q complex binding	C4A C4B	8.83e-04	10	90	2	GO:0001849
GeneOntologyBiologicalProcess	complement activation	CFH C4A C4B C8A C8B FCN3	6.11e-07	70	90	6	GO:0006956
GeneOntologyBiologicalProcess	kidney development	CFH SLIT2 HNF1B FBN1 RARA TMEM59L LRP2 LRP4 RET NOTCH1	5.13e-06	372	90	10	GO:0001822
GeneOntologyBiologicalProcess	renal system development	CFH SLIT2 HNF1B FBN1 RARA TMEM59L LRP2 LRP4 RET NOTCH1	7.09e-06	386	90	10	GO:0072001
GeneOntologyBiologicalProcess	humoral immune response	CFH WFDC2 DEFB127 C4A C4B C8A C8B FCN3 NOTCH1	1.12e-05	321	90	9	GO:0006959
GeneOntologyBiologicalProcess	complement activation, classical pathway	C4A C4B C8A C8B	4.03e-05	44	90	4	GO:0006958
GeneOntologyBiologicalProcess	apoptotic cell clearance	RARA C4A C4B FCN3	5.69e-05	48	90	4	GO:0043277
GeneOntologyBiologicalProcess	complement activation, alternative pathway	CFH C8A C8B	7.40e-05	19	90	3	GO:0006957
GeneOntologyBiologicalProcess	kidney epithelium development	SLIT2 HNF1B RARA TMEM59L RET NOTCH1	7.73e-05	162	90	6	GO:0072073
GeneOntologyBiologicalProcess	ureteric bud development	SLIT2 HNF1B RARA TMEM59L RET	1.06e-04	107	90	5	GO:0001657
GeneOntologyBiologicalProcess	sequestering of TGFbeta in extracellular matrix	FBN1 LTBP1	1.12e-04	4	90	2	GO:0035583
GeneOntologyBiologicalProcess	mesonephric tubule development	SLIT2 HNF1B RARA TMEM59L RET	1.21e-04	110	90	5	GO:0072164
GeneOntologyBiologicalProcess	mesonephric epithelium development	SLIT2 HNF1B RARA TMEM59L RET	1.21e-04	110	90	5	GO:0072163
GeneOntologyBiologicalProcess	mesonephros development	SLIT2 HNF1B RARA TMEM59L RET	1.37e-04	113	90	5	GO:0001823
GeneOntologyBiologicalProcess	humoral immune response mediated by circulating immunoglobulin	C4A C4B C8A C8B	1.56e-04	62	90	4	GO:0002455
GeneOntologyBiologicalProcess	innate immune response	CFH MST1R DEFB105A NLRP10 WFDC2 DEFB127 TRIM62 C4A C4B C8A C8B FCN3 F12 TRIM10	2.61e-04	1092	90	14	GO:0045087
GeneOntologyBiologicalProcess	regulation of biological process involved in symbiotic interaction	FBLN1 TRIM62 FCN3 TRIM10	3.25e-04	75	90	4	GO:0043903
GeneOntologyCellularComponent	extracellular matrix	CCN6 SLIT2 FBLN1 THBS4 ADAM19 FBN1 VWF LAMC1 LAMC3 MUC5B LTBP1 RTBDN FCN3 MUC5AC ADAMTSL4 F12	2.16e-08	656	91	16	GO:0031012
GeneOntologyCellularComponent	external encapsulating structure	CCN6 SLIT2 FBLN1 THBS4 ADAM19 FBN1 VWF LAMC1 LAMC3 MUC5B LTBP1 RTBDN FCN3 MUC5AC ADAMTSL4 F12	2.25e-08	658	91	16	GO:0030312
GeneOntologyCellularComponent	collagen-containing extracellular matrix	SLIT2 FBLN1 THBS4 ADAM19 FBN1 VWF LAMC1 LAMC3 LTBP1 RTBDN FCN3 ADAMTSL4 F12	4.87e-07	530	91	13	GO:0062023
GeneOntologyCellularComponent	symbiont cell surface	CFH C4A C4B	4.40e-06	8	91	3	GO:0106139
GeneOntologyCellularComponent	other organism part	CFH C4A C4B	6.58e-06	9	91	3	GO:0044217
GeneOntologyCellularComponent	basement membrane	FBLN1 THBS4 FBN1 LAMC1 LAMC3	1.94e-04	122	91	5	GO:0005604
GeneOntologyCellularComponent	cell surface	CFH MST1R SLIT2 ADAM19 VWF SCUBE2 LRP2 LRP4 PAM LY6K RTBDN BSN FCN3 NOTCH1	3.06e-04	1111	91	14	GO:0009986
GeneOntologyCellularComponent	membrane attack complex	C8A C8B	3.88e-04	7	91	2	GO:0005579
GeneOntologyCellularComponent	blood microparticle	CFH C4A C4B C8A FCN3	4.18e-04	144	91	5	GO:0072562
GeneOntologyCellularComponent	somatodendritic compartment	CFH SLIT2 KLHL24 RARA LRP2 LRP4 PAM C4A C4B LTBP1 RET BSN PCDH8 ASAP1	8.28e-04	1228	91	14	GO:0036477
GeneOntologyCellularComponent	dendrite	SLIT2 RARA LRP2 LRP4 C4A C4B LTBP1 RET BSN PCDH8 ASAP1	1.24e-03	858	91	11	GO:0030425
GeneOntologyCellularComponent	dendritic tree	SLIT2 RARA LRP2 LRP4 C4A C4B LTBP1 RET BSN PCDH8 ASAP1	1.26e-03	860	91	11	GO:0097447
GeneOntologyCellularComponent	microfibril	FBN1 LTBP1	1.42e-03	13	91	2	GO:0001527
GeneOntologyCellularComponent	serine-type endopeptidase complex	CFH FCN3	3.38e-03	20	91	2	GO:1905370
GeneOntologyCellularComponent	neuronal cell body	CFH SLIT2 KLHL24 LRP4 PAM C4A C4B LTBP1 RET BSN	3.39e-03	835	91	10	GO:0043025
HumanPheno	Reduced circulating complement concentration	CFH C4A C4B C8A C8B	4.02e-05	58	35	5	HP:0004431
HumanPheno	Decreased circulating complement C8 concentration	C8A C8B	4.59e-05	2	35	2	HP:0004434
HumanPheno	Abnormality of complement system	CFH C4A C4B C8A C8B	5.14e-05	61	35	5	HP:0005339
MousePheno	abnormal artery morphology	CFH SLIT2 FBLN1 CMIP ADAM19 FBN1 WFDC2 LRP2 PAM LTBP1 ODAD2 NOTCH1	2.63e-06	440	73	12	MP:0002191
MousePheno	abnormal thoracic aorta morphology	SLIT2 FBLN1 CMIP FBN1 LRP2 LTBP1 ODAD2	6.12e-06	134	73	7	MP:0010468
MousePheno	perimembraneous ventricular septal defect	SLIT2 FBLN1 ADAM19 LRP2 LTBP1 ODAD2	8.23e-06	92	73	6	MP:0010418
MousePheno	abnormal interventricular septum membranous part morphology	SLIT2 FBLN1 ADAM19 LRP2 LTBP1 ODAD2	8.76e-06	93	73	6	MP:0008823
MousePheno	abnormal cyst	SLIT2 CMIP DZIP1L ARIH2 LRP2 LAMC1 LTBP1 ODAD2 RET	2.13e-05	294	73	9	MP:0031310
MousePheno	abnormal aorta morphology	SLIT2 FBLN1 CMIP ADAM19 FBN1 LRP2 LTBP1 ODAD2	2.17e-05	225	73	8	MP:0000272
MousePheno	abnormal aortic arch morphology	SLIT2 FBLN1 CMIP LRP2 LTBP1 ODAD2	3.59e-05	119	73	6	MP:0004113
MousePheno	kidney cyst	SLIT2 DZIP1L ARIH2 LRP2 LAMC1 LTBP1 RET	3.74e-05	177	73	7	MP:0003675
MousePheno	muscular ventricular septal defect	SLIT2 FBLN1 CMIP LRP2 ODAD2	4.99e-05	77	73	5	MP:0010420
MousePheno	abnormal interventricular septum muscular part morphology	SLIT2 FBLN1 CMIP LRP2 ODAD2	5.64e-05	79	73	5	MP:0010498
MousePheno	increased urine microglobulin level	LRP2 GPRC6A	8.04e-05	3	73	2	MP:0011555
MousePheno	abnormal systemic artery morphology	SLIT2 FBLN1 CMIP ADAM19 FBN1 LRP2 LTBP1 ODAD2	1.80e-04	304	73	8	MP:0011655
MousePheno	decreased spleen germinal center size	C4A C4B ABCC10	1.96e-04	22	73	3	MP:0008484
MousePheno	abnormal ureteric bud morphology	SLIT2 LRP4 LAMC1 RET	2.19e-04	57	73	4	MP:0006032
MousePheno	hydronephrosis	BSND SLIT2 LRP2 LAMC1 RET	2.59e-04	109	73	5	MP:0000519
MousePheno	decreased spleen germinal center number	C4A C4B ABCC10	3.26e-04	26	73	3	MP:0008482
MousePheno	abnormal nephron morphology	CFH FBLN1 DZIP1L LRP2 LAMC1 C4A C4B LTBP1 RET	3.59e-04	426	73	9	MP:0003881
MousePheno	ventricular septal defect	SLIT2 FBLN1 CMIP ADAM19 LRP2 LTBP1 ODAD2	4.16e-04	261	73	7	MP:0010402
MousePheno	abnormal respiratory motile cilium morphology	WFDC2 ODAD2 AK7	4.53e-04	29	73	3	MP:0011050
MousePheno	abnormal kidney pelvis morphology	BSND SLIT2 LRP2 LAMC1 RET	4.70e-04	124	73	5	MP:0004194
Domain	EGF-like_dom	ATRN SLIT2 HGFAC FBLN1 THBS4 ADAM19 FBN1 SCUBE2 LRP2 LRP4 LAMC1 LAMC3 LTBP1 C8A C8B F12 NOTCH1	3.02e-15	249	90	17	IPR000742
Domain	EGF_1	ATRN SLIT2 HGFAC FBLN1 THBS4 ADAM19 FBN1 SCUBE2 LRP2 LRP4 LAMC1 LAMC3 LTBP1 C8A C8B F12 NOTCH1	4.48e-15	255	90	17	PS00022
Domain	EGF-like_CS	ATRN SLIT2 HGFAC FBLN1 THBS4 ADAM19 FBN1 SCUBE2 LRP2 LRP4 LAMC1 LAMC3 LTBP1 C8A C8B F12 NOTCH1	6.59e-15	261	90	17	IPR013032
Domain	EGF_2	ATRN SLIT2 HGFAC FBLN1 THBS4 ADAM19 FBN1 SCUBE2 LRP2 LRP4 LAMC1 LAMC3 LTBP1 C8A C8B F12 NOTCH1	8.48e-15	265	90	17	PS01186
Domain	EGF_3	ATRN SLIT2 HGFAC FBLN1 THBS4 ADAM19 FBN1 SCUBE2 LRP2 LRP4 LTBP1 C8A C8B F12 NOTCH1	3.98e-13	235	90	15	PS50026
Domain	Growth_fac_rcpt_	CCN6 ATRN FBLN1 THBS4 FBN1 SCUBE2 LRP2 LRP4 LAMC1 LAMC3 LTBP1 C8A NOTCH1	5.48e-13	156	90	13	IPR009030
Domain	EGF	ATRN SLIT2 HGFAC FBLN1 THBS4 FBN1 SCUBE2 LRP2 LRP4 LAMC1 LAMC3 LTBP1 F12 NOTCH1	6.56e-12	235	90	14	SM00181
Domain	EGF_CA	SLIT2 FBLN1 THBS4 FBN1 SCUBE2 LRP2 LRP4 LTBP1 F12 NOTCH1	3.58e-10	122	90	10	SM00179
Domain	EGF-like_Ca-bd_dom	SLIT2 FBLN1 THBS4 FBN1 SCUBE2 LRP2 LRP4 LTBP1 F12 NOTCH1	4.21e-10	124	90	10	IPR001881
Domain	EGF	ATRN SLIT2 HGFAC THBS4 SCUBE2 LRP2 LRP4 LTBP1 F12 NOTCH1	4.93e-10	126	90	10	PF00008
Domain	EGF_Ca-bd_CS	SLIT2 FBLN1 THBS4 FBN1 SCUBE2 LRP2 LRP4 LTBP1 NOTCH1	9.40e-10	97	90	9	IPR018097
Domain	EGF_CA	SLIT2 FBLN1 THBS4 FBN1 SCUBE2 LRP2 LRP4 LTBP1 NOTCH1	1.13e-09	99	90	9	PS01187
Domain	cEGF	FBLN1 FBN1 SCUBE2 LRP2 LRP4 LTBP1	2.25e-09	26	90	6	PF12662
Domain	cEGF	FBLN1 FBN1 SCUBE2 LRP2 LRP4 LTBP1	2.25e-09	26	90	6	IPR026823
Domain	EGF_CA	FBLN1 THBS4 FBN1 SCUBE2 LRP2 LRP4 LTBP1 NOTCH1	8.27e-09	86	90	8	PF07645
Domain	CTCK_1	CCN6 SLIT2 VWF MUC5B MUC5AC	1.89e-08	18	90	5	PS01185
Domain	ASX_HYDROXYL	SLIT2 FBLN1 FBN1 SCUBE2 LRP2 LRP4 LTBP1 NOTCH1	2.74e-08	100	90	8	PS00010
Domain	EGF-type_Asp/Asn_hydroxyl_site	SLIT2 FBLN1 FBN1 SCUBE2 LRP2 LRP4 LTBP1 NOTCH1	4.35e-08	106	90	8	IPR000152
Domain	CT	CCN6 SLIT2 VWF MUC5B MUC5AC	5.73e-08	22	90	5	SM00041
Domain	Cys_knot_C	CCN6 SLIT2 VWF MUC5B MUC5AC	1.14e-07	25	90	5	IPR006207
Domain	CTCK_2	CCN6 SLIT2 VWF MUC5B MUC5AC	1.14e-07	25	90	5	PS01225
Domain	TIL_dom	VWF LRP2 MUC5B MUC5AC	4.86e-07	14	90	4	IPR002919
Domain	TSP_1	CCN6 ADGRB3 THSD7B C8A C8B ADAMTSL4	5.76e-07	63	90	6	PF00090
Domain	TSP1	CCN6 ADGRB3 THSD7B C8A C8B ADAMTSL4	6.95e-07	65	90	6	SM00209
Domain	TSP1_rpt	CCN6 ADGRB3 THSD7B C8A C8B ADAMTSL4	6.95e-07	65	90	6	IPR000884
Domain	TSP1	CCN6 ADGRB3 THSD7B C8A C8B ADAMTSL4	6.95e-07	65	90	6	PS50092
Domain	ANATO	FBLN1 C4A C4B	3.73e-06	7	90	3	SM00104
Domain	ANAPHYLATOXIN_2	FBLN1 C4A C4B	3.73e-06	7	90	3	PS01178
Domain	ANAPHYLATOXIN_1	FBLN1 C4A C4B	3.73e-06	7	90	3	PS01177
Domain	ANATO	FBLN1 C4A C4B	3.73e-06	7	90	3	PF01821
Domain	Anaphylatoxin/fibulin	FBLN1 C4A C4B	3.73e-06	7	90	3	IPR000020
Domain	Coagulation_fac_XIIa/HGFA	HGFAC F12	2.30e-05	2	90	2	IPR014394
Domain	C8	VWF MUC5B MUC5AC	2.31e-05	12	90	3	PF08742
Domain	TIL	VWF MUC5B MUC5AC	2.31e-05	12	90	3	PF01826
Domain	Unchr_dom_Cys-rich	VWF MUC5B MUC5AC	2.99e-05	13	90	3	IPR014853
Domain	C8	VWF MUC5B MUC5AC	2.99e-05	13	90	3	SM00832
Domain	LDLR_class-A_CS	LRP2 LRP4 C8A C8B	4.04e-05	40	90	4	IPR023415
Domain	Glyco_hormone_CN	CCN6 MUC5B MUC5AC	4.72e-05	15	90	3	IPR006208
Domain	Cys_knot	CCN6 MUC5B MUC5AC	4.72e-05	15	90	3	PF00007
Domain	VWF_type-D	VWF MUC5B MUC5AC	5.79e-05	16	90	3	IPR001846
Domain	VWFD	VWF MUC5B MUC5AC	5.79e-05	16	90	3	PS51233
Domain	VWD	VWF MUC5B MUC5AC	5.79e-05	16	90	3	SM00216
Domain	VWD	VWF MUC5B MUC5AC	5.79e-05	16	90	3	PF00094
Domain	Ldl_recept_a	LRP2 LRP4 C8A C8B	6.46e-05	45	90	4	PF00057
Domain	LDLRA_1	LRP2 LRP4 C8A C8B	8.34e-05	48	90	4	PS01209
Domain	LDrepeatLR_classA_rpt	LRP2 LRP4 C8A C8B	9.05e-05	49	90	4	IPR002172
Domain	LDLa	LRP2 LRP4 C8A C8B	9.05e-05	49	90	4	SM00192
Domain	LDLRA_2	LRP2 LRP4 C8A C8B	9.05e-05	49	90	4	PS50068
Domain	VWC_out	VWF MUC5B MUC5AC	9.92e-05	19	90	3	SM00215
Domain	FN1_2	HGFAC F12	1.37e-04	4	90	2	PS51091
Domain	fn1	HGFAC F12	1.37e-04	4	90	2	PF00039
Domain	Fibronectin_type1	HGFAC F12	1.37e-04	4	90	2	IPR000083
Domain	FN1	HGFAC F12	1.37e-04	4	90	2	SM00058
Domain	FN1_1	HGFAC F12	1.37e-04	4	90	2	PS01253
Domain	EGF_extracell	ATRN ADAM19 LRP2 NOTCH1	2.00e-04	60	90	4	IPR013111
Domain	EGF_2	ATRN ADAM19 LRP2 NOTCH1	2.00e-04	60	90	4	PF07974
Domain	Anaphylatoxin_comp_syst	C4A C4B	2.27e-04	5	90	2	IPR018081
Domain	Anaphylatoxn_comp_syst_dom	C4A C4B	2.27e-04	5	90	2	IPR001840
Domain	VWC	VWF MUC5B MUC5AC	3.25e-04	28	90	3	PF00093
Domain	MACPF_CS	C8A C8B	3.40e-04	6	90	2	IPR020863
Domain	WxxW_domain	MUC5B MUC5AC	3.40e-04	6	90	2	IPR025155
Domain	Mucin2_WxxW	MUC5B MUC5AC	3.40e-04	6	90	2	PF13330
Domain	EGF_LAM_2	ATRN LAMC1 LAMC3	4.00e-04	30	90	3	PS50027
Domain	EGF_LAM_1	ATRN LAMC1 LAMC3	4.00e-04	30	90	3	PS01248
Domain	TB	FBN1 LTBP1	4.75e-04	7	90	2	PF00683
Domain	MACPF_2	C8A C8B	4.75e-04	7	90	2	PS51412
Domain	MACPF_1	C8A C8B	4.75e-04	7	90	2	PS00279
Domain	MacrogloblnA2_thiol-ester-bond	C4A C4B	6.31e-04	8	90	2	IPR019565
Domain	-	FBN1 LTBP1	6.31e-04	8	90	2	3.90.290.10
Domain	Thiol-ester_cl	C4A C4B	6.31e-04	8	90	2	PF10569
Domain	LAMININ_IVA	LAMC1 LAMC3	6.31e-04	8	90	2	PS51115
Domain	Laminin_B	LAMC1 LAMC3	6.31e-04	8	90	2	PF00052
Domain	MacrogloblnA2_CS	C4A C4B	6.31e-04	8	90	2	IPR019742
Domain	LamB	LAMC1 LAMC3	6.31e-04	8	90	2	SM00281
Domain	Laminin_IV	LAMC1 LAMC3	6.31e-04	8	90	2	IPR000034
Domain	EGF_Lam	ATRN LAMC1 LAMC3	6.33e-04	35	90	3	SM00180
Domain	Laminin_EGF	ATRN LAMC1 LAMC3	6.33e-04	35	90	3	PF00053
Domain	VWFC_1	VWF MUC5B MUC5AC	6.89e-04	36	90	3	PS01208
Domain	VWFC_2	VWF MUC5B MUC5AC	8.08e-04	38	90	3	PS50184
Domain	VWC	VWF MUC5B MUC5AC	8.08e-04	38	90	3	SM00214
Domain	Laminin_EGF	ATRN LAMC1 LAMC3	8.08e-04	38	90	3	IPR002049
Domain	TB_dom	FBN1 LTBP1	8.09e-04	9	90	2	IPR017878
Domain	TB	FBN1 LTBP1	8.09e-04	9	90	2	PS51364
Domain	-	LRP2 LRP4 PAM	8.72e-04	39	90	3	2.120.10.30
Domain	MAC_perforin	C8A C8B	1.01e-03	10	90	2	IPR001862
Domain	A2M	C4A C4B	1.01e-03	10	90	2	PF00207
Domain	A2M_N_2	C4A C4B	1.01e-03	10	90	2	IPR011625
Domain	A2M_comp	C4A C4B	1.01e-03	10	90	2	IPR011626
Domain	A2M_recep	C4A C4B	1.01e-03	10	90	2	PF07677
Domain	A2M_comp	C4A C4B	1.01e-03	10	90	2	PF07678
Domain	A2M_N	C4A C4B	1.01e-03	10	90	2	PF01835
Domain	A2M_N	C4A C4B	1.01e-03	10	90	2	IPR002890
Domain	A-macroglobulin_rcpt-bd	C4A C4B	1.01e-03	10	90	2	IPR009048
Domain	ALPHA_2_MACROGLOBULIN	C4A C4B	1.01e-03	10	90	2	PS00477
Domain	A2M_N_2	C4A C4B	1.01e-03	10	90	2	PF07703
Domain	Macroglobln_a2	C4A C4B	1.01e-03	10	90	2	IPR001599
Domain	VWF_dom	VWF MUC5B MUC5AC	1.08e-03	42	90	3	IPR001007
Domain	Znf_RING_CS	TRIM62 ARIH2 PCGF5 TRIM10 PDZRN4	1.15e-03	163	90	5	IPR017907
Domain	MACPF	C8A C8B	1.23e-03	11	90	2	PF01823
Domain	6-blade_b-propeller_TolB-like	LRP2 LRP4 PAM	1.41e-03	46	90	3	IPR011042
Pathway	KEGG_COMPLEMENT_AND_COAGULATION_CASCADES	CFH VWF C4A C4B C8A C8B F12	6.84e-08	69	74	7	M16894
Pathway	WP_COMPLEMENT_ACTIVATION_CLASSICAL_PATHWAY	C4A C4B C8A C8B	1.58e-06	17	74	4	MM15944
Pathway	WP_COMPLEMENT_ACTIVATION	C4A C4B C8A C8B	4.76e-06	22	74	4	M39502
Pathway	WP_COMPLEMENT_SYSTEM	CFH LRP2 LAMC1 C4A C8A F12	1.09e-05	96	74	6	M39581
Pathway	WP_COMPLEMENT_SYSTEM_IN_NEURONAL_DEVELOPMENT_AND_PLASTICITY	CFH C4A C4B C8A C8B FCN3	1.92e-05	106	74	6	M42535
Pathway	KEGG_MEDICUS_REFERENCE_LECTIN_PATHWAY_OF_COMPLEMENT_CASCADE_C4_C2_TO_C3_CONVERTASE_FORMATION	C4A C4B FCN3	2.22e-05	11	74	3	M47874
Pathway	REACTOME_DISEASES_ASSOCIATED_WITH_O_GLYCOSYLATION_OF_PROTEINS	MUC5B THSD7B MUC5AC ADAMTSL4 NOTCH1	2.80e-05	68	74	5	M27303
Pathway	REACTOME_COMPLEMENT_CASCADE	CFH C4A C4B C8A C8B FCN3	3.05e-05	115	74	6	M19752
Pathway	KEGG_PRION_DISEASES	LAMC1 C8A C8B NOTCH1	3.24e-05	35	74	4	M13036
Pathway	BIOCARTA_LECTIN_PATHWAY	C4A C4B C8A	3.82e-05	13	74	3	M4732
Pathway	BIOCARTA_CLASSIC_PATHWAY	C4A C4B C8A	6.04e-05	15	74	3	M7146
Pathway	REACTOME_COMPLEMENT_CASCADE	CFH C4A C4B C8A C8B	7.77e-05	84	74	5	MM14653
Pathway	REACTOME_KIDNEY_DEVELOPMENT	SLIT2 HNF1B WFDC2 RET	9.66e-05	46	74	4	M48243
Pathway	BIOCARTA_COMP_PATHWAY	C4A C4B C8A	1.48e-04	20	74	3	M917
Pathway	REACTOME_EXTRACELLULAR_MATRIX_ORGANIZATION	FBLN1 ADAM19 FBN1 VWF LRP4 LAMC1 LAMC3 LTBP1	1.71e-04	300	74	8	M610
Pathway	WP_COMPLEMENT_AND_COAGULATION_CASCADES	CFH VWF C4B F12	2.40e-04	58	74	4	M39649
Pathway	WP_DENGUE2_INTERACTIONS_WITH_COMPLEMENT_AND_COAGULATION_CASCADES	CFH VWF C4B F12	2.56e-04	59	74	4	M48343
Pathway	WP_DEVELOPMENT_OF_URETERIC_COLLECTION_SYSTEM	SLIT2 HNF1B RARA RET	2.73e-04	60	74	4	M40048
Pathway	REACTOME_ACTIVATION_OF_C3_AND_C5	C4A C4B	5.61e-04	7	74	2	MM14685
Pathway	KEGG_MEDICUS_REFERENCE_COMMON_PATHWAY_OF_COMPLEMENT_CASCADE_MAC_FORMATION	C8A C8B	5.61e-04	7	74	2	M47873
Pathway	REACTOME_ACTIVATION_OF_C3_AND_C5	C4A C4B	7.46e-04	8	74	2	M27031
Pathway	REACTOME_TERMINAL_PATHWAY_OF_COMPLEMENT	C8A C8B	7.46e-04	8	74	2	M27006
Pathway	KEGG_MEDICUS_REFERENCE_CLASSICAL_PATHWAY_OF_COMPLEMENT_CASCADE_C4_C2_TO_C3_CONVERTASE_FORMATION	C4A C4B	7.46e-04	8	74	2	M47872
Pathway	KEGG_MEDICUS_REFERENCE_PLASMIN_MEDIATED_ACTIVATION_OF_LATENT_TGF_BETA	FBN1 LTBP1	7.46e-04	8	74	2	M47850
Pathway	REACTOME_TERMINAL_PATHWAY_OF_COMPLEMENT	C8A C8B	7.46e-04	8	74	2	MM14656
Pathway	REACTOME_DISEASES_OF_GLYCOSYLATION	MUC5B THSD7B MUC5AC ADAMTSL4 NOTCH1	9.20e-04	143	74	5	M27275
Pathway	REACTOME_MOLECULES_ASSOCIATED_WITH_ELASTIC_FIBRES	FBLN1 FBN1 LTBP1	9.49e-04	37	74	3	M27134
Pathway	KEGG_MEDICUS_REFERENCE_REGULATION_OF_COMPLEMENT_CASCADE_MAC_INHIBITION	C8A C8B	9.56e-04	9	74	2	M47881
Pathway	KEGG_ECM_RECEPTOR_INTERACTION	THBS4 VWF LAMC1 LAMC3	9.83e-04	84	74	4	M7098
Pathway	WP_ALLOGRAFT_REJECTION	C4A C4B C8A C8B	1.22e-03	89	74	4	M39398
Pathway	BIOCARTA_LECTIN_PATHWAY	C4A C4B	1.45e-03	11	74	2	MM1430
Pathway	WP_GENES_CONTROLLING_NEPHROGENESIS	SLIT2 HNF1B RET	1.58e-03	44	74	3	M39891
Pathway	REACTOME_ELASTIC_FIBRE_FORMATION	FBLN1 FBN1 LTBP1	1.58e-03	44	74	3	M26969
Pathway	BIOCARTA_CLASSIC_PATHWAY	C4A C4B	1.73e-03	12	74	2	MM1368
Pathway	PID_A6B1_A6B4_INTEGRIN_PATHWAY	MST1R LAMC1 LAMC3	1.79e-03	46	74	3	M239
Pathway	REACTOME_DISEASES_OF_METABOLISM	GCLC MUC5B THSD7B MUC5AC ADAMTSL4 NOTCH1	1.98e-03	250	74	6	M27554
Pathway	KEGG_MEDICUS_REFERENCE_WNT_SIGNALING_MODULATION_SOST_LRP4	FZD8 LRP4	2.37e-03	14	74	2	M47834
Pathway	REACTOME_O_LINKED_GLYCOSYLATION	MUC5B THSD7B MUC5AC ADAMTSL4	2.57e-03	109	74	4	MM15164
Pathway	REACTOME_O_LINKED_GLYCOSYLATION	MUC5B THSD7B MUC5AC ADAMTSL4	2.74e-03	111	74	4	M27416
Pubmed	Extracellular matrix secretion by cardiac fibroblasts: role of microRNA-29b and microRNA-30c.	CFH SLIT2 FBLN1 FBN1 VWF LAMC1 C4A C4B LTBP1 ADAMTSL4	1.22e-09	248	92	10	24006456
Pubmed	Human plasma N-glycoproteome analysis by immunoaffinity subtraction, hydrazide chemistry, and mass spectrometry.	CFH ATRN HGFAC LAMC1 C4A C8A C8B FCN3 ADAMTSL4 F12	1.73e-09	257	92	10	16335952
Pubmed	Screening for N-glycosylated proteins by liquid chromatography mass spectrometry.	CFH ATRN VWF C4A C4B F12	2.86e-09	47	92	6	14760718
Pubmed	Functional analysis of Ficolin-3 mediated complement activation.	C4A C4B FCN3	7.15e-08	4	92	3	21085669
Pubmed	Extracellular matrix signatures of human primary metastatic colon cancers and their metastases to liver.	FBLN1 FBN1 VWF LAMC1 LTBP1 ADAMTSL4 F12	1.78e-07	153	92	7	25037231
Pubmed	The matrisome: in silico definition and in vivo characterization by proteomics of normal and tumor extracellular matrices.	FBLN1 THBS4 ADAM19 FBN1 VWF LAMC1 LTBP1	3.23e-07	167	92	7	22159717
Pubmed	Complement activation via alternative pathway is critical in the development of laser-induced choroidal neovascularization: role of factor B and factor H.	CFH C4A C4B	3.56e-07	6	92	3	16849499
Pubmed	In-depth proteomic analyses of exosomes isolated from expressed prostatic secretions in urine.	CFH ATRN FBLN1 THBS4 WFDC2 LRP2 PAM LAMC1 C4A C4B MUC5B C8A C8B F12	8.46e-07	1070	92	14	23533145
Pubmed	EMILIN proteins are novel extracellular constituents of the dentin-pulp complex.	FBLN1 FBN1 LAMC1	9.94e-07	8	92	3	32948785
Pubmed	Local anesthetics impair the growth and self-renewal of glioblastoma stem cells by inhibiting ZDHHC15-mediated GP130 palmitoylation.	FBN1 LRP2 LAMC1 LIMCH1 MUC5AC	1.32e-06	71	92	5	33541421
Pubmed	Microfibril-associated glycoprotein-2 interacts with fibrillin-1 and fibrillin-2 suggesting a role for MAGP-2 in elastic fiber assembly.	FBLN1 FBN1 VWF	1.49e-06	9	92	3	12122015
Pubmed	Complement Inhibitor CRIg/FH Ameliorates Renal Ischemia Reperfusion Injury via Activation of PI3K/AKT Signaling.	FBN1 C4A C4B	2.12e-06	10	92	3	30429287
Pubmed	Combination of factor H mutation and properdin deficiency causes severe C3 glomerulonephritis.	CFH C4A C4B	2.91e-06	11	92	3	23204401
Pubmed	ESCPE-1 mediates retrograde endosomal sorting of the SARS-CoV-2 host factor Neuropilin-1.	CFH MST1R ATRN FBLN1 FBN1 LRP4 PAM LAMC1 LAMC3 C4A LTBP1 LY6K USP48 NOTCH1	3.25e-06	1201	92	14	35696571
Pubmed	HNF1B controls proximal-intermediate nephron segment identity in vertebrates by regulating Notch signalling components and Irx1/2.	HNF1B WFDC2 LRP2 NOTCH1	3.90e-06	40	92	4	23362348
Pubmed	New sequence variants associated with bone mineral density.	ADAM19 LRP4 SP7	6.38e-06	14	92	3	19079262
Pubmed	Neuroepithelial body microenvironment is a niche for a distinct subset of Clara-like precursors in the developing airways.	MUC5B MUC5AC NOTCH1	6.38e-06	14	92	3	22797898
Pubmed	Cloning and analysis of cDNA encoding a major airway glycoprotein, human tracheobronchial mucin (MUC5).	MUC5B MUC5AC	6.92e-06	2	92	2	7513696
Pubmed	Copy number analysis of complement C4A, C4B and C4A silencing mutation by real-time quantitative polymerase chain reaction.	C4A C4B	6.92e-06	2	92	2	22737222
Pubmed	Deficiency of C4 from donor or recipient mouse fails to prevent renal allograft rejection.	C4A C4B	6.92e-06	2	92	2	16565498
Pubmed	Complete deficiencies of complement C4A and C4B including 2-bp insertion in codon 1213 are genetic risk factors of systemic lupus erythematosus in Thai populations.	C4A C4B	6.92e-06	2	92	2	15998580
Pubmed	High-throughput analysis of the C4 polymorphism by a combination of MLPA and isotype-specific ELISA's.	C4A C4B	6.92e-06	2	92	2	19062096
Pubmed	The association between MUC5AC and MUC5B genes expression and remodeling progression in severe neutrophilic asthma: A direct relationship.	MUC5B MUC5AC	6.92e-06	2	92	2	37146737
Pubmed	Activation of innate and humoral immunity in the peripheral nervous system of ALS transgenic mice.	C4A C4B	6.92e-06	2	92	2	19933335
Pubmed	Contact activation-induced complex formation between complement factor H and coagulation factor XIIa.	CFH F12	6.92e-06	2	92	2	31984663
Pubmed	MUC5AC and MUC5B Mucins Are Decreased in Cystic Fibrosis Airway Secretions.	MUC5B MUC5AC	6.92e-06	2	92	2	14988081
Pubmed	Structural basis for the C4d.1/C4d.2 serologic allotypes of murine complement component C4.	C4A C4B	6.92e-06	2	92	2	2459207
Pubmed	Antigen-induced B cell apoptosis is independent of complement C4.	C4A C4B	6.92e-06	2	92	2	17645767
Pubmed	The interaction between factor H and Von Willebrand factor.	CFH VWF	6.92e-06	2	92	2	23991205
Pubmed	Anti-DNA autoreactivity in C4-deficient mice.	C4A C4B	6.92e-06	2	92	2	12207352
Pubmed	Mucin glycosylation changes in cystic fibrosis lung disease are not manifest in submucosal gland secretions.	MUC5B MUC5AC	6.92e-06	2	92	2	15563276
Pubmed	The expression of MUC5AC and MUC5B mucin genes in the mucosa of chronic rhinosinusitis and nasal polyposis.	MUC5B MUC5AC	6.92e-06	2	92	2	17621824
Pubmed	Muc5b is required for airway defence.	MUC5B MUC5AC	6.92e-06	2	92	2	24317696
Pubmed	Complement C4A and C4B Gene Copy Number Study in Alzheimer's Disease Patients.	C4A C4B	6.92e-06	2	92	2	27758680
Pubmed	Genetically determined partial complement C4 deficiency states are not independent risk factors for SLE in UK and Spanish populations.	C4A C4B	6.92e-06	2	92	2	22387014
Pubmed	Macrophages are related to goblet cell hyperplasia and induce MUC5B but not MUC5AC in human bronchus epithelial cells.	MUC5B MUC5AC	6.92e-06	2	92	2	22391959
Pubmed	Mucins MUC5AC and MUC5B Are Variably Packaged in the Same and in Separate Secretory Granules.	MUC5B MUC5AC	6.92e-06	2	92	2	35776514
Pubmed	Complement C4 maintains peripheral B-cell tolerance in a myeloid cell dependent manner.	C4A C4B	6.92e-06	2	92	2	23749435
Pubmed	Copy number variations of complement component C4 are associated with Behçet's disease but not with ankylosing spondylitis associated with acute anterior uveitis.	C4A C4B	6.92e-06	2	92	2	23918728
Pubmed	The N-Terminal Region of Fibrillin-1 Mediates a Bipartite Interaction with LTBP1.	FBN1 LTBP1	6.92e-06	2	92	2	28669633
Pubmed	The ocular surface phenotype of Muc5ac and Muc5b null mice.	MUC5B MUC5AC	6.92e-06	2	92	2	24327612
Pubmed	Molecular genetics of androgen-dependent and -independent expression of mouse sex-limited protein.	C4A C4B	6.92e-06	2	92	2	3037333
Pubmed	Evidence of a role for C4 in modulating interstitial inflammation in experimental glomerulonephritis.	C4A C4B	6.92e-06	2	92	2	11726230
Pubmed	Quantitative variations in the expression of the mouse serum antigen Ss and its sex-limited allotype Slp.	C4A C4B	6.92e-06	2	92	2	4216347
Pubmed	Sequence determination of the thiolester site of the fourth component of human complement.	C4A C4B	6.92e-06	2	92	2	6950384
Pubmed	Visual demonstration of the organization of the human complement C4 and 21-hydroxylase genes by high-resolution fluorescence in situ hybridization.	C4A C4B	6.92e-06	2	92	2	8660986
Pubmed	Tissue-specific RNA processing for the complement C4 gene transcript in the H-2k mouse strain.	C4A C4B	6.92e-06	2	92	2	8428773
Pubmed	Complement C4 deficiency--a plausible risk factor for non-tuberculous mycobacteria (NTM) infection in apparently immunocompetent patients.	C4A C4B	6.92e-06	2	92	2	24638111
Pubmed	Transcriptional repression of C4 complement by hepatitis C virus proteins.	C4A C4B	6.92e-06	2	92	2	21345967
Pubmed	Differential functional expression of the C8 subunits. Primary role of C8 beta in assembly of intact C8.	C8A C8B	6.92e-06	2	92	2	3171181
Pubmed	Gel-forming mucins form distinct morphologic structures in airways.	MUC5B MUC5AC	6.92e-06	2	92	2	28607090
Pubmed	Restriction fragment analysis of H-2 recombinant mouse strains with crossovers between E alpha and C4 genes.	C4A C4B	6.92e-06	2	92	2	2572548
Pubmed	The complement component C4 of mammals.	C4A C4B	6.92e-06	2	92	2	2302180
Pubmed	Gene CNVs and protein levels of complement C4A and C4B as novel biomarkers for partial disease remissions in new-onset type 1 diabetes patients.	C4A C4B	6.92e-06	2	92	2	22151770
Pubmed	Hepatocyte nuclear factor-1beta enhances the stemness of hepatocellular carcinoma cells through activation of the Notch pathway.	HNF1B NOTCH1	6.92e-06	2	92	2	28684878
Pubmed	C4d-positive chronic rejection: a frequent entity with a poor outcome.	C4A C4B	6.92e-06	2	92	2	18091514
Pubmed	Comprehensive approach to study complement C4 in systemic lupus erythematosus: Gene polymorphisms, protein levels and functional activity.	C4A C4B	6.92e-06	2	92	2	29080553
Pubmed	Genes for murine fourth complement component (C4) and sex-limited protein (Slp) identified by hybridization to C4- and Slp-specific cDNA.	C4A C4B	6.92e-06	2	92	2	6589636
Pubmed	C4 Deficiency is a predisposing factor for Streptococcus pneumoniae-induced autoantibody production.	C4A C4B	6.92e-06	2	92	2	25339671
Pubmed	A study of association of the complement C4 mutations with systemic lupus erythematosus in the Malaysian population.	C4A C4B	6.92e-06	2	92	2	17728371
Pubmed	Muc5b is mainly expressed and sialylated in the nasal olfactory epithelium whereas Muc5ac is exclusively expressed and fucosylated in the nasal respiratory epithelium.	MUC5B MUC5AC	6.92e-06	2	92	2	31030254
Pubmed	Structure and organization of the C4 genes.	C4A C4B	6.92e-06	2	92	2	6149580
Pubmed	Sequence heterogeneity of murine complementary DNA clones related to the C4 and C4-Slp isoforms of the fourth complement component.	C4A C4B	6.92e-06	2	92	2	6149581
Pubmed	The idiopathic pulmonary fibrosis honeycomb cyst contains a mucocilary pseudostratified epithelium.	MUC5B MUC5AC	6.92e-06	2	92	2	23527003
Pubmed	The follicular dendritic cell restricted epitope, FDC-M2, is complement C4; localization of immune complexes in mouse tissues.	C4A C4B	6.92e-06	2	92	2	12115608
Pubmed	Biochemistry and biology of anaphylatoxins.	C4A C4B	6.92e-06	2	92	2	3542363
Pubmed	C4 from C4-high and C4-low mouse strains have identical sequences in the region corresponding to the isotype-specific segment of human C4.	C4A C4B	6.92e-06	2	92	2	2387317
Pubmed	Up-regulation of MUC5AC and MUC5B mucin genes in nasopharyngeal respiratory mucosa and selective up-regulation of MUC5B in middle ear in pediatric otitis media with effusion.	MUC5B MUC5AC	6.92e-06	2	92	2	16540890
Pubmed	Role of ADAMTSL4 mutations in FBN1 mutation-negative ectopia lentis patients.	FBN1 ADAMTSL4	6.92e-06	2	92	2	20564469
Pubmed	Identification of the size and antigenic determinants of the human C4 gene by a polymerase chain-reaction-based amplification method.	C4A C4B	6.92e-06	2	92	2	16908004
Pubmed	Structural studies on the murine fourth component of complement (C4). IV. Demonstration that C4 and Slp are encoded by separate loci.	C4A C4B	6.92e-06	2	92	2	7365238
Pubmed	Abnormalities in MUC5AC and MUC5B Protein in Airway Mucus in Asthma.	MUC5B MUC5AC	6.92e-06	2	92	2	27845589
Pubmed	Interaction between the labile binding sites of the fourth (C4) and fifth (C5) human complement proteins and erythrocyte cell membranes.	C4A C4B	6.92e-06	2	92	2	7391573
Pubmed	Peritubular capillary C4d deposition in lupus nephritis different from antibody-mediated renal rejection.	C4A C4B	6.92e-06	2	92	2	17971360
Pubmed	Clinical features of patients with homozygous complement C4A or C4B deficiency.	C4A C4B	6.92e-06	2	92	2	29928053
Pubmed	Analysis of C4 and the C4 binding protein in the MRL/lpr mouse.	C4A C4B	6.92e-06	2	92	2	17971229
Pubmed	Genetic deficiency of C4 presenting with recurrent infections and a SLE-like disease. Genetic and immunologic studies.	C4A C4B	6.92e-06	2	92	2	6881182
Pubmed	Contribution of mucus concentration and secreted mucins Muc5ac and Muc5b to the pathogenesis of muco-obstructive lung disease.	MUC5B MUC5AC	6.92e-06	2	92	2	27435107
Pubmed	Mucins MUC5B and MUC5AC in Distal Airways and Honeycomb Spaces: Comparison among Idiopathic Pulmonary Fibrosis/Usual Interstitial Pneumonia, Fibrotic Nonspecific Interstitial Pneumonitis, and Control Lungs.	MUC5B MUC5AC	6.92e-06	2	92	2	26871672
Pubmed	Partial C4 deficiency in juvenile idiopathic arthritis patients.	C4A C4B	6.92e-06	2	92	2	17921792
Pubmed	Complement activation and complement receptors on follicular dendritic cells are critical for the function of a targeted adjuvant.	C4A C4B	6.92e-06	2	92	2	21880985
Pubmed	Amino acid sequence around the thiol and reactive acyl groups of human complement component C4.	C4A C4B	6.92e-06	2	92	2	6978711
Pubmed	Plasma Complement 3 and Complement 4 Are Promising Biomarkers for Distinguishing NMOSD From MOGAD and Are Associated With the Blood-Brain-Barrier Disruption in NMOSD.	C4A C4B	6.92e-06	2	92	2	35898513
Pubmed	Borrelia burgdorferi outer surface protein C (OspC) binds complement component C4b and confers bloodstream survival.	C4A C4B	6.92e-06	2	92	2	28873507
Pubmed	The eighth component of human complement. Purification and physicochemical characterization of its unusual subunit structure.	C8A C8B	6.92e-06	2	92	2	7440581
Pubmed	Studies on the murine Ss protein: demonstration that the Ss protein is functionally the fourth component of complement.	C4A C4B	6.92e-06	2	92	2	276882
Pubmed	Amino acid sequence of a polymorphic segment from fragment C4d of human complement component C4.	C4A C4B	6.92e-06	2	92	2	6832377
Pubmed	Recombination of two homologous MHC class III genes of the mouse (C4 and Slp) that accounts for the loss of testosterone dependence of sex-limited protein expression.	C4A C4B	6.92e-06	2	92	2	3794341
Pubmed	In silico cloning of mouse Muc5b gene and upregulation of its expression in mouse asthma model.	MUC5B MUC5AC	6.92e-06	2	92	2	11587997
Pubmed	Fine-tuned characterization of RCCX copy number variants and their relationship with extended MHC haplotypes.	C4A C4B	6.92e-06	2	92	2	22785613
Pubmed	The interaction between factor H and VWF increases factor H cofactor activity and regulates VWF prothrombotic status.	CFH VWF	6.92e-06	2	92	2	24014239
Pubmed	A genotype-phenotype comparison of ADAMTSL4 and FBN1 in isolated ectopia lentis.	FBN1 ADAMTSL4	6.92e-06	2	92	2	22736615
Pubmed	Association between complement 4 copy number variation and systemic lupus erythematosus: a meta-analysis.	C4A C4B	6.92e-06	2	92	2	32691186
Pubmed	The androgen-dependent C4-Slp gene is driven by a constitutively competent promoter.	C4A C4B	6.92e-06	2	92	2	8390682
Pubmed	Pathophysiological relevance of sputum MUC5AC and MUC5B levels in patients with mild asthma.	MUC5B MUC5AC	6.92e-06	2	92	2	34656442
Pubmed	Structure and expression of murine fourth complement component (C4) and sex-limited protein (Slp).	C4A C4B	6.92e-06	2	92	2	3902619
Pubmed	Structural polymorphism of murine C4 and its linkage to H-2.	C4A C4B	6.92e-06	2	92	2	7373044
Pubmed	The chemical structure of the C4d fragment of the human complement component C4.	C4A C4B	6.92e-06	2	92	2	3696167
Pubmed	Airway mucin MUC5AC and MUC5B concentrations and the initiation and progression of chronic obstructive pulmonary disease: an analysis of the SPIROMICS cohort.	MUC5B MUC5AC	6.92e-06	2	92	2	34058148
Pubmed	Restriction fragment length polymorphism of the murine C4 and Slp genes: two C4 groups.	C4A C4B	6.92e-06	2	92	2	1357031
Interaction	NTN5 interactions	FBN1 LRP2 LRP4 LTBP1 NOTCH1	6.67e-08	24	91	5	int:NTN5
Interaction	ZFP41 interactions	FBLN1 FBN1 ARIH2 LRP2 LRP4 LTBP1	2.16e-07	57	91	6	int:ZFP41
Interaction	IGFL3 interactions	ATRN FBLN1 LRP2 LRP4 NOTCH1	2.26e-05	75	91	5	int:IGFL3
GeneFamily	Complement system\|Sushi domain containing	CFH C4A C4B C8A C8B	2.07e-07	36	67	5	492
GeneFamily	C3 and PZP like, alpha-2-macroglobulin domain containing	C4A C4B	4.79e-04	9	67	2	1234
GeneFamily	Laminin subunits	LAMC1 LAMC3	8.72e-04	12	67	2	626
GeneFamily	Low density lipoprotein receptors	LRP2 LRP4	1.03e-03	13	67	2	634
GeneFamily	CD molecules\|Mucins	MUC5B MUC5AC	2.71e-03	21	67	2	648
Coexpression	HAY_BONE_MARROW_STROMAL	CFH FZD8 CCN6 SLIT2 FBLN1 FBN1 NALCN NPB WFDC2 ARHGEF10 LAMC1 TNFRSF19 LIMCH1 LY6K THSD7B PLEKHH2 PDZRN4	1.29e-09	767	92	17	M39209
Coexpression	NABA_ECM_GLYCOPROTEINS	CCN6 SLIT2 FBLN1 THBS4 FBN1 VWF LAMC1 LAMC3 LTBP1	2.48e-08	191	92	9	MM17059
Coexpression	NABA_ECM_GLYCOPROTEINS	CCN6 SLIT2 FBLN1 THBS4 FBN1 VWF LAMC1 LAMC3 LTBP1	3.09e-08	196	92	9	M3008
Coexpression	NABA_MATRISOME	CCN6 SLIT2 HGFAC FBLN1 THBS4 ADAM19 FBN1 VWF SCUBE2 LAMC1 LAMC3 MUC5B LTBP1 FCN3 MUC5AC ADAMTSL4 F12	9.24e-08	1026	92	17	M5889
Coexpression	GAO_LARGE_INTESTINE_ADULT_CJ_IMMUNE_CELLS	CFH FBLN1 ADAM19 FBN1 VWF SCUBE2 ADGRB3 PAM LAMC1 LAMC3 LIMCH1 ASAP1	2.06e-07	505	92	12	M39167
Coexpression	NABA_MATRISOME	CCN6 SLIT2 HGFAC FBLN1 THBS4 ADAM19 FBN1 VWF SCUBE2 LAMC1 LAMC3 MUC5B LTBP1 MUC5AC ADAMTSL4 F12	4.12e-07	1008	92	16	MM17056
Coexpression	NABA_CORE_MATRISOME	CCN6 SLIT2 FBLN1 THBS4 FBN1 VWF LAMC1 LAMC3 LTBP1	4.71e-07	270	92	9	MM17057
Coexpression	NABA_CORE_MATRISOME	CCN6 SLIT2 FBLN1 THBS4 FBN1 VWF LAMC1 LAMC3 LTBP1	5.49e-07	275	92	9	M5884
Coexpression	HALLMARK_COAGULATION	CFH FBN1 VWF C8A C8B F12	9.39e-06	138	92	6	M5946
Coexpression	PICCALUGA_ANGIOIMMUNOBLASTIC_LYMPHOMA_UP	CFH FBN1 VWF ARHGEF10 LAMC1 C4A	1.02e-04	211	92	6	M12225
CoexpressionAtlas	kidney_P4_CapMesRenVes_Crym_top-relative-expression-ranked_1000	SLIT2 FBLN1 HNF1B FBN1 WFDC2 LRP2 LRP4 LAMC1 PRRG4 LTBP1 PLEKHH2 NOTCH1 ASAP1	2.85e-05	783	91	13	gudmap_kidney_P4_CapMesRenVes_Crym_1000
CoexpressionAtlas	kidney_P2_CapMes_Crym_k-means-cluster#4_top-relative-expression-ranked_1000	CMIP WFDC2 GCLC PRRG4 LIMCH1	2.89e-05	83	91	5	gudmap_kidney_P2_CapMes_Crym_k4_1000
CoexpressionAtlas	kidney_P4_CapMesRenVes_Crym_top-relative-expression-ranked_500	SLIT2 HNF1B WFDC2 LRP2 LRP4 LAMC1 PRRG4 LTBP1 NOTCH1	5.27e-05	398	91	9	gudmap_kidney_P4_CapMesRenVes_Crym_500
CoexpressionAtlas	Stromal Cells, Fi.MTS15+.Th, CD45- PDGFRa+ MTS15+, Thymus, avg-3	CFH FBLN1 FBN1 LAMC1 LTBP1	6.11e-05	97	91	5	GSM777043_100
CoexpressionAtlas	kidney_P4_CapMesRenVes_Crym_top-relative-expression-ranked_200	HNF1B WFDC2 LRP4 LAMC1 LTBP1 NOTCH1	1.07e-04	175	91	6	gudmap_kidney_P4_CapMesRenVes_Crym_200
CoexpressionAtlas	Stromal Cells, Fi.MTS15+.Th, CD45- PDGFRa+ MTS15+, Thymus, avg-3	CFH SLIT2 FBLN1 FBN1 PAM LAMC1 LTBP1 RET PLEKHH2	1.23e-04	445	91	9	GSM777043_500
CoexpressionAtlas	kidney_P4_CapMesRenVes_Crym_k-means-cluster#3_top-relative-expression-ranked_200	HNF1B LRP4 LAMC1 NOTCH1	1.46e-04	62	91	4	gudmap_kidney_P4_CapMesRenVes_Crym_k3_200
CoexpressionAtlas	Stromal Cells, FRC.MLN, gp38+ CD31- CD140a+, Lymph Node, avg-5	CFH FBLN1 FBN1 PAM LAMC1 C4A C4B LTBP1 PLEKHH2	1.74e-04	466	91	9	GSM777050_500
CoexpressionAtlas	kidney_P3_CapMes_Crym_k-means-cluster#4_top-relative-expression-ranked_200	HNF1B LRP4 LAMC1 LTBP1	1.75e-04	65	91	4	gudmap_kidney_P3_CapMes_Crym_k4_200
CoexpressionAtlas	kidney_P3_CapMes_Crym_top-relative-expression-ranked_500	SLIT2 HNF1B CMIP WFDC2 LRP4 LAMC1 LTBP1 NOTCH1	1.90e-04	370	91	8	gudmap_kidney_P3_CapMes_Crym_500
ToppCell	facs-Lung-nan-3m-Mesenchymal-fibroblast_of_lung\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CFH SLIT2 FBLN1 FBN1 SCUBE2 LAMC1 TNFRSF19 LTBP1 LIMCH1 PLEKHH2	4.95e-12	182	92	10	c557de6ccd327c46e0a5423cd9936d78e0abae5f
ToppCell	facs-Lung-nan-3m-Mesenchymal-Alveolar_Fibroblast\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CFH SLIT2 FBLN1 FBN1 SCUBE2 LAMC1 TNFRSF19 LTBP1 LIMCH1 PLEKHH2	4.95e-12	182	92	10	dbe4b2557cf19e0682ed446f8397d3a1153642f0
ToppCell	15-Trachea-Epithelial-Secretory_progenitor\|Trachea / Age, Tissue, Lineage and Cell class	CFH KLHL24 SCUBE2 WFDC2 ADGRB3 PAM LAMC1 MUC5B HOOK2	1.97e-10	187	92	9	be9fce9e74b2f170a2067f1b31d802912a578329
ToppCell	droplet-Lung-18m-Mesenchymal-fibroblast\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	CFH SLIT2 FBLN1 FBN1 SCUBE2 LRP4 TNFRSF19 C4B LIMCH1	2.16e-10	189	92	9	e76dc36a01d8ad7590b3acc4c46abfcb76857448
ToppCell	droplet-Lung-immune-endo-depleted-3m-Mesenchymal-fibroblast_of_lung\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CFH SLIT2 FBLN1 FBN1 SCUBE2 LRP4 LAMC1 TNFRSF19 LIMCH1	2.38e-10	191	92	9	a261f0738d974784bbdd60f23092bfbcca464459
ToppCell	facs-Lung-24m-Mesenchymal-fibroblast\|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	CFH FBLN1 FBN1 SCUBE2 LRP4 LAMC1 C4B LTBP1 LIMCH1	2.38e-10	191	92	9	094c9d3270fc1e487ccf10fb4936af5f081f6009
ToppCell	droplet-Lung-21m-Mesenchymal-fibroblast\|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	CFH SLIT2 FBLN1 FBN1 SCUBE2 LRP4 TNFRSF19 C4B LIMCH1	2.38e-10	191	92	9	8a73d2df079566fca4cbb5cdb85721c2e87134c8
ToppCell	droplet-Lung-immune-endo-depleted-3m-Mesenchymal-Alveolar_Fibroblast\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CFH SLIT2 FBLN1 FBN1 SCUBE2 LRP4 LAMC1 TNFRSF19 LIMCH1	2.38e-10	191	92	9	6594398cc8151c73696391a43ac110c10283dab1
ToppCell	facs-Lung-24m-Mesenchymal\|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	CFH FBLN1 FBN1 SCUBE2 LRP4 LAMC1 C4B LTBP1 LIMCH1	2.38e-10	191	92	9	ba02cbdfda6a94374a6472eb88499059979af472
ToppCell	droplet-Lung-1m-Mesenchymal-fibroblast-alveolar_fibroblast\|1m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	CFH SLIT2 FBLN1 FBN1 SCUBE2 LAMC1 TNFRSF19 LTBP1 LIMCH1	2.38e-10	191	92	9	d04e6292fef189b8d8ed0f4b0c310b2b250fd30e
ToppCell	nucseq-Mesenchymal-Fibroblastic-Fibroblastic_2\|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	CFH SLIT2 FBLN1 FBN1 ADGRB3 LAMC1 LTBP1 LIMCH1 PLEKHH2	2.49e-10	192	92	9	99ce9e3c4c50cf64ebb62145f2b5420efa0db309
ToppCell	COVID-19-Fibroblasts-Other_FB\|COVID-19 / group, cell type (main and fine annotations)	CFH SLIT2 FBLN1 FBN1 NALCN TNFRSF19 LTBP1 LIMCH1 PLEKHH2	2.61e-10	193	92	9	e6b75be08e33c1de079fb5c02f0b4468128b369c
ToppCell	Bronchial-10x5prime-Stromal-Peri/Epineurial_\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	CFH THBS4 FBN1 C4A MUC5B RET PLEKHH2 PCDH8 PDZRN4	3.42e-10	199	92	9	45c3b853900d8c3d5965117d904e3714100138bc
ToppCell	droplet-Lung-3m-Mesenchymal-fibroblast-adventitial_fibroblast-adventitial_fibroblast_l49\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	CFH FBLN1 NLRP10 LRP4 LAMC3 C4A C4B LIMCH1	2.28e-09	168	92	8	d2b91f2adc95dcfa623f8d7ca2df1c6f884da988
ToppCell	(0)_Normal/No_Treatment-(3)_LEPR+_perivascular_cells\|World / Stress and Cell class	CFH SLIT2 FBN1 LRP4 PAM C4B LTBP1 LIMCH1	3.29e-09	176	92	8	ce2c32b5ce0da848eb4da35ce4d215cdf74d9113
ToppCell	5'-Adult-LargeIntestine-Mesenchymal-fibroblastic-Stromal_3_(C7+)\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	SLIT2 FBLN1 THBS4 FBN1 SCUBE2 PAM LAMC1 PLEKHH2	4.28e-09	182	92	8	3dfa9187e9d2bab1d199079d29209c4648220ada
ToppCell	facs-Lung-EPCAM-24m-Mesenchymal\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CFH FBLN1 FBN1 SCUBE2 LRP4 C4B LTBP1 LIMCH1	5.75e-09	189	92	8	324c81285c51f4f8bb1aef428b18fe2c549c2c11
ToppCell	facs-Lung-EPCAM-24m-Mesenchymal-fibroblast_of_lung\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CFH FBLN1 FBN1 SCUBE2 LRP4 C4B LTBP1 LIMCH1	6.00e-09	190	92	8	00fd993675faf53adf985b9316a18c8a33242029
ToppCell	droplet-Lung-18m-Mesenchymal\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	CFH FBLN1 FBN1 SCUBE2 LRP4 TNFRSF19 C4B LIMCH1	6.00e-09	190	92	8	0b7200897b2c389632c9b1ee37e272b811555dbc
ToppCell	facs-Lung-EPCAM-24m-Mesenchymal-Alveolar_Fibroblast\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CFH FBLN1 FBN1 SCUBE2 LRP4 C4B LTBP1 LIMCH1	6.00e-09	190	92	8	8cda09d761c6b504a744959d587c183f94f1beeb
ToppCell	droplet-Lung-3m-Mesenchymal-fibroblast\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	CFH FBLN1 FBN1 LRP4 PAM LAMC1 C4B LIMCH1	6.25e-09	191	92	8	44a9a6768084dafc641ad455b65862bfd4cc0cb9
ToppCell	droplet-Lung-18m-Mesenchymal-fibroblast-alveolar_fibroblast-alveolar_fibroblast_l49\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	CFH SLIT2 FBLN1 FBN1 SCUBE2 LRP4 TNFRSF19 LIMCH1	6.25e-09	191	92	8	36467322096bc766cd777dae3bfb4e65511e492c
ToppCell	droplet-Lung-18m-Mesenchymal-fibroblast-alveolar_fibroblast\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	CFH SLIT2 FBLN1 FBN1 SCUBE2 LRP4 TNFRSF19 LIMCH1	6.25e-09	191	92	8	94795daf05061baa3b72a1b01c9e940af86de044
ToppCell	droplet-Lung-1m-Mesenchymal-fibroblast\|1m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	CFH SLIT2 FBLN1 FBN1 SCUBE2 LAMC1 LTBP1 LIMCH1	6.25e-09	191	92	8	ce80f65bd24b1c4d2152bf45248449e7a1a97e56
ToppCell	droplet-Lung-1m-Mesenchymal-fibroblast-alveolar_fibroblast-alveolar_fibroblast_l49\|1m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	CFH SLIT2 FBLN1 FBN1 SCUBE2 TNFRSF19 LTBP1 LIMCH1	6.25e-09	191	92	8	de3e9b704621b26836c2ddc39fa3e840dfb4541b
ToppCell	facs-Lung-3m-Mesenchymal-fibroblast\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	CFH FBLN1 FBN1 SCUBE2 LRP4 LAMC1 C4B LTBP1	6.25e-09	191	92	8	997abf0cc5873bed0372c4a333ed307fa72774d2
ToppCell	nucseq-Mesenchymal-Fibroblastic-Fibroblastic_2-AF1\|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	CFH SLIT2 FBLN1 FBN1 ADGRB3 LAMC1 LIMCH1 PLEKHH2	6.25e-09	191	92	8	6688cee34beee4f151ac17fccbc9c26a9aad72e1
ToppCell	droplet-Lung-21m-Mesenchymal\|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	CFH FBLN1 FBN1 SCUBE2 LRP4 TNFRSF19 C4B LIMCH1	6.25e-09	191	92	8	10a9db1caa0fdb51ace8537f42b2c66f7c97e0f5
ToppCell	droplet-Lung-nan-18m-Mesenchymal-Alveolar_Fibroblast\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CFH SLIT2 FBLN1 SCUBE2 LRP4 TNFRSF19 LTBP1 LIMCH1	6.51e-09	192	92	8	d22c1135867bcb9076435e2c6eb1cc1248990d0c
ToppCell	(0)_Normal/No_Treatment-(3)_LEPR+_perivascular_cells\|(0)_Normal/No_Treatment / Stress and Cell class	CFH SLIT2 FBN1 LRP4 PAM C4B LTBP1 LIMCH1	6.51e-09	192	92	8	7a2ad0bdae647b88e799e62767605f2f3c5a426f
ToppCell	droplet-Lung-nan-18m-Mesenchymal-fibroblast_of_lung\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CFH SLIT2 FBLN1 SCUBE2 LRP4 TNFRSF19 LTBP1 LIMCH1	6.51e-09	192	92	8	c09966f4d63a739a56db4df7e0e0ee9ecacd21ad
ToppCell	PND28-Mesenchymal-Mesenchymal_structural-Fibroblastic-AF1-AF1_mature\|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	CFH SLIT2 FBLN1 FBN1 SCUBE2 LAMC1 LIMCH1 PLEKHH2	6.78e-09	193	92	8	4c74a3f69b2cbdf139e7e66b44bd86869ac34dc0
ToppCell	PND28-Mesenchymal-Mesenchymal_structural-Fibroblastic-AF1\|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	CFH SLIT2 FBLN1 FBN1 SCUBE2 LAMC1 LIMCH1 PLEKHH2	6.78e-09	193	92	8	ff8ceeb3cfd1bef7239df490c19d181091750833
ToppCell	LA\|World / Chamber and Cluster_Paper	SLIT2 FBLN1 ADAM19 FBN1 LRP2 LAMC1 PLEKHH2 PDZRN4	6.78e-09	193	92	8	d4bf89437216baf489ea0239136dcedf3b6714af
ToppCell	RV-02._Fibroblast_II\|RV / Chamber and Cluster_Paper	CFH SLIT2 DPYD FBLN1 FBN1 ADGRB3 LAMC1 PDZRN4	7.06e-09	194	92	8	11c79a8c56ece42713b04b321982e41e239f07a5
ToppCell	LV-02._Fibroblast_II\|LV / Chamber and Cluster_Paper	CFH SLIT2 FBLN1 FBN1 ADGRB3 LAMC1 PLEKHH2 PDZRN4	7.06e-09	194	92	8	014d2feb5db2a6a35ef759761a41e466e108c3c1
ToppCell	nucseq-Mesenchymal-Fibroblastic\|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	CFH SLIT2 FBLN1 FBN1 ADGRB3 LAMC1 LTBP1 PLEKHH2	7.65e-09	196	92	8	7d8505dac15fa59935ccf592afc54b04c4c6554f
ToppCell	COVID-19-Fibroblasts\|COVID-19 / group, cell type (main and fine annotations)	CFH SLIT2 FBLN1 FBN1 ADGRB3 LAMC1 LTBP1 PLEKHH2	7.96e-09	197	92	8	fb847f2277609c31fffcdf49517243ce0684facf
ToppCell	nucseq-Mesenchymal\|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	CFH SLIT2 FBLN1 FBN1 ADGRB3 LAMC1 LTBP1 PLEKHH2	8.28e-09	198	92	8	8f52243ca8b9ba68a75ae411506a3a6de258eb97
ToppCell	LPS_anti-TNF-Mesenchymal_fibroblastic-Fibroblasts-MatrixFB\|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type	SLIT2 FBLN1 FBN1 SCUBE2 LAMC1 LTBP1 LIMCH1 PLEKHH2	8.96e-09	200	92	8	9b0916d8d07ac2bf1739f7be5296bf77ffee6094
ToppCell	Bronchial-NucSeq-Stromal\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	CFH SLIT2 FBLN1 FBN1 ADGRB3 LTBP1 PLEKHH2 PDZRN4	8.96e-09	200	92	8	389cc775c8419d90fb77cd794376d2160a7bf44e
ToppCell	5'-Adult-SmallIntestine-Mesenchymal-fibroblastic-Transitional_Stromal_3_(C3+)\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	CFH SLIT2 FBLN1 FBN1 PAM LAMC1 ADAMTSL4 PDZRN4	8.96e-09	200	92	8	6f7f015b5fa1f52374f2c7d9ba339012395eda5f
ToppCell	5'-Adult-SmallIntestine-Mesenchymal-fibroblastic\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	CFH SLIT2 FBLN1 FBN1 PAM LAMC1 ADAMTSL4 PDZRN4	8.96e-09	200	92	8	3a164e3971bcd62b148b813171c103adb81f972e
ToppCell	3'-Pediatric_IBD-SmallIntestine-Mesenchymal-fibroblastic-Stromal_3_(C7+)\|Pediatric_IBD / Celltypes from developing, pediatric, Crohn's, & adult GI tract	CFH SLIT2 FBLN1 PAM PLEKHH2 BSN ADAMTSL4	9.24e-08	179	92	7	dcd0a83f0592ae27f814d064b4791f84c3c86e64
ToppCell	5'-Adult-SmallIntestine-Mesenchymal-fibroblastic-Stromal_1_(ADAMDEC1+)\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	CFH FBLN1 CMIP FBN1 TMEM59L C4A PLEKHH2	9.60e-08	180	92	7	f2f6e83127a4a415e65c76a35efa8175fbd5b5d9
ToppCell	Children_(3_yrs)-Mesenchymal-myofibroblast_cell\|Children_(3_yrs) / Lineage, Cell type, age group and donor	CFH FBN1 NALCN ADGRB3 TNFRSF19 LTBP1 PLEKHH2	9.60e-08	180	92	7	01f2e5d96016823482f89ba503d007d4bd88eeac
ToppCell	P28-Mesenchymal-mesenchymal_fibroblast\|P28 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	CFH SLIT2 FBLN1 FBN1 SCUBE2 LRP4 LIMCH1	9.97e-08	181	92	7	091e7975badd1ffa463a8ec87908be20781ecfd6
ToppCell	Children_(3_yrs)-Mesenchymal-matrix_fibroblast_1_cell-D046\|Children_(3_yrs) / Lineage, Cell type, age group and donor	SLIT2 FBLN1 FBN1 ADGRB3 LAMC1 TNFRSF19 PLEKHH2	9.97e-08	181	92	7	9ede19228ba5c0668a9c06c915510b95585216ef
ToppCell	facs-Liver-Hepatocytes-24m-Epithelial\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	HGFAC DPYD HNF1B GCLC C8A C8B F12	1.04e-07	182	92	7	770ce9f3f4538d0181a0181543841bc964c68274
ToppCell	facs-Liver-Hepatocytes-24m-Epithelial-nan\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	HGFAC DPYD HNF1B GCLC C8A C8B F12	1.04e-07	182	92	7	77ab860e2add49dad0c1ffbfc64278ad499dfbd5
ToppCell	facs-Liver-Hepatocytes-24m-Epithelial-hepatocyte\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	HGFAC DPYD HNF1B GCLC C8A C8B F12	1.04e-07	182	92	7	4921c7d5687cc79f896b39753bb621d7e3d2972f
ToppCell	LA-01._Fibroblast_I\|World / Chamber and Cluster_Paper	SLIT2 FBLN1 FBN1 ADGRB3 LAMC1 PLEKHH2 ADAMTSL4	1.24e-07	187	92	7	4ea486991f66c29728d127171a07b81404ec0b78
ToppCell	Control-Fibroblasts-Other_FB\|Control / group, cell type (main and fine annotations)	CFH SLIT2 FBLN1 FBN1 NALCN LTBP1 PLEKHH2	1.24e-07	187	92	7	bd3739c4a52aa1ba5deffd778e113a9800f7e158
ToppCell	COVID-19-Heart-Fib_1\|COVID-19 / Disease (COVID-19 only), tissue and cell type	CFH SLIT2 FBLN1 FBN1 ADGRB3 LAMC1 LTBP1	1.29e-07	188	92	7	fe361215f4ba841aa5e1e581fb56f2f4d3ccd201
ToppCell	droplet-Lung-immune-endo-depleted\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CFH FBLN1 FBN1 LRP4 PAM LAMC1 LIMCH1	1.34e-07	189	92	7	c3fb363bb0156ffb3367c200f548faebda64ab4a
ToppCell	facs-Lung-18m-Mesenchymal\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	CFH FBLN1 FBN1 SCUBE2 LRP4 C4B LIMCH1	1.34e-07	189	92	7	bdf8db938aa0863c4fed6fa99dcffd63c8c20c31
ToppCell	droplet-Lung-immune-endo-depleted-3m\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CFH FBLN1 FBN1 LRP4 PAM LAMC1 LIMCH1	1.34e-07	189	92	7	2a2953f6b1b7d070d739dcaf7285fce6e097d9e4
ToppCell	facs-Lung-18m-Mesenchymal-fibroblast\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	CFH FBLN1 FBN1 SCUBE2 LRP4 C4B LIMCH1	1.34e-07	189	92	7	40cbd679dc0548bf5207e1b033c0597886ad6fe1
ToppCell	LPS_only-Stromal_mesenchymal-Matrix_Fibroblast-MatrixFB\|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	SLIT2 FBLN1 FBN1 SCUBE2 ADGRB3 LIMCH1 PLEKHH2	1.34e-07	189	92	7	2a22b9fae70afb3dab8476f9c00e48a4df756410
ToppCell	droplet-Lung-3m\|Lung / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	CFH FBLN1 FBN1 LRP4 PAM LAMC1 LIMCH1	1.34e-07	189	92	7	5a636e952da9b1fd26aa17f7b129054f2da322b5
ToppCell	droplet-Lung-immune-endo-depleted-3m-Mesenchymal\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CFH FBLN1 FBN1 LRP4 PAM LAMC1 LIMCH1	1.39e-07	190	92	7	9cd147a174017ebda23cc47b6d4552d898acd092
ToppCell	Control-Fibroblasts\|Control / group, cell type (main and fine annotations)	CFH SLIT2 FBLN1 FBN1 ADGRB3 LTBP1 PLEKHH2	1.39e-07	190	92	7	3a42a9b98d954685d38a741f44545898d0e3e9ce
ToppCell	LPS-IL1RA+antiTNF-Stromal_mesenchymal-Matrix_Fibroblast-Activated_MatrixFB\|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	SLIT2 FBLN1 FBN1 SCUBE2 ADGRB3 LIMCH1 PLEKHH2	1.44e-07	191	92	7	b13229bb7f3713a392271aaf5dbae3edd1b9fe5a
ToppCell	facs-Lung-3m-Mesenchymal-fibroblast-alveolar_fibroblast\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	CFH SLIT2 SCUBE2 LRP4 TNFRSF19 LTBP1 LIMCH1	1.44e-07	191	92	7	beb5bb42bd53bce01339da9110d374901548793c
ToppCell	facs-Lung-3m-Mesenchymal-fibroblast-alveolar_fibroblast-alveolar_fibroblast_l49\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	CFH SLIT2 SCUBE2 LRP4 TNFRSF19 LTBP1 LIMCH1	1.44e-07	191	92	7	6609d85fd2577633dcc067507304a6f9e5865ca3
ToppCell	droplet-Lung-21m-Mesenchymal-fibroblast-alveolar_fibroblast-alveolar_fibroblast_l49\|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	SLIT2 FBLN1 FBN1 SCUBE2 LRP4 TNFRSF19 LIMCH1	1.44e-07	191	92	7	c715bbdbbf1482aad45a50a16d5232fd35a9a0bb
ToppCell	facs-Lung-24m-Mesenchymal-fibroblast-alveolar_fibroblast\|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	CFH FBLN1 FBN1 SCUBE2 LRP4 LTBP1 LIMCH1	1.44e-07	191	92	7	80484d39f34703a33b9bac09826b7a526e883cab
ToppCell	droplet-Lung-21m-Mesenchymal-fibroblast-alveolar_fibroblast\|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	SLIT2 FBLN1 FBN1 SCUBE2 LRP4 TNFRSF19 LIMCH1	1.44e-07	191	92	7	243d83cbfcc4996ad087ec6386e559e0b8662004
ToppCell	facs-Lung-18m-Mesenchymal-fibroblast-alveolar_fibroblast\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	CFH SLIT2 FBLN1 SCUBE2 LRP4 TNFRSF19 LIMCH1	1.44e-07	191	92	7	d4f535b06ad483448ab692e9900c872c78cbed60
ToppCell	facs-Lung-24m-Mesenchymal-fibroblast-alveolar_fibroblast-alveolar_fibroblast_l49\|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	CFH FBLN1 FBN1 SCUBE2 LRP4 LTBP1 LIMCH1	1.44e-07	191	92	7	5c4e4e9de14edfae072a2a2882220a31bebf51b2
ToppCell	droplet-Lung-1m-Mesenchymal\|1m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	CFH FBLN1 FBN1 SCUBE2 LAMC1 LTBP1 LIMCH1	1.49e-07	192	92	7	01433bd4794b8bcc51fe4249124a0f4289b9d6e2
ToppCell	droplet-Lung-nan-18m-Mesenchymal\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CFH FBLN1 FBN1 SCUBE2 LRP4 TNFRSF19 LIMCH1	1.49e-07	192	92	7	df56c3e3bb1aafc1126607f4426554c09c8c40cf
ToppCell	droplet-Lung-18m-Mesenchymal-fibroblast-adventitial_fibroblast-adventitial_fibroblast_l49\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	CFH SLIT2 FBLN1 FBN1 SCUBE2 C4B LIMCH1	1.49e-07	192	92	7	1b228f0929b505de82a39bf64c837887b0e56701
ToppCell	facs-Lung-3m-Mesenchymal\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	CFH FBLN1 FBN1 LRP4 LAMC1 C4B LTBP1	1.49e-07	192	92	7	8df15085b35b86f39debd933284cb703c5dd63c2
ToppCell	droplet-Lung-3m-Mesenchymal\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	CFH FBLN1 FBN1 LRP4 PAM LAMC1 LIMCH1	1.49e-07	192	92	7	086b47f87283cd41139cd56686011f8b5821b0da
ToppCell	droplet-Lung-30m-Mesenchymal-fibroblast-alveolar_fibroblast-alveolar_fibroblast_l49\|30m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	SLIT2 DPYD FBLN1 FBN1 SCUBE2 TNFRSF19 LIMCH1	1.49e-07	192	92	7	ff4b728a55c2550c806c47e9ae3d057c35df8464
ToppCell	droplet-Lung-30m-Mesenchymal-fibroblast-alveolar_fibroblast\|30m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	SLIT2 DPYD FBLN1 FBN1 SCUBE2 TNFRSF19 LIMCH1	1.49e-07	192	92	7	2d3790bd80a7f214b37094121a2a86ff16362569
ToppCell	facs-Lung-EPCAM-18m-Mesenchymal\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CFH FBLN1 FBN1 SCUBE2 LRP4 C4B LIMCH1	1.49e-07	192	92	7	5876ff75e273a48e7ad8236423fb41e4ae4c0a91
ToppCell	(2)_5-FU-(2)_LEPR+_perivascular_cells_and_VE-Cad+_vascular_cells_(mixed)\|World / Stress and Cell class	CFH SLIT2 FBN1 PAM C4B LTBP1 LIMCH1	1.54e-07	193	92	7	f31398dad5321a7bcb27e208bd73630e9756e897
ToppCell	PND28-Mesenchymal-Mesenchymal_structural\|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	CFH FBLN1 FBN1 SCUBE2 LAMC1 C4B LIMCH1	1.54e-07	193	92	7	ec81c1afdae2e0433a22c8c1fa1c6232526ff7e7
ToppCell	droplet-Heart-HEART_(ALL_MINUS_AORTA)-30m-Mesenchymal-fibroblast_of_cardiac_tissue\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CFH FBLN1 FBN1 LAMC1 C4B LTBP1 ADAMTSL4	1.54e-07	193	92	7	0a665531d581d4e3941e29d3f95569da8f166447
ToppCell	Children_(3_yrs)-Mesenchymal-matrix_fibroblast_1_cell\|Children_(3_yrs) / Lineage, Cell type, age group and donor	SLIT2 FBLN1 FBN1 ADGRB3 LAMC1 LIMCH1 PLEKHH2	1.54e-07	193	92	7	99525545552b371c86b18b6ea6f4897dc6e9a9ec
ToppCell	droplet-Heart-HEART_(ALL_MINUS_AORTA)-30m-Mesenchymal-fibroblast\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CFH FBLN1 FBN1 LAMC1 C4B LTBP1 ADAMTSL4	1.54e-07	193	92	7	24ce1f37cca655415410d2403a52d1ebb3332280
ToppCell	PND28-Mesenchymal-Mesenchymal_structural-Fibroblastic\|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	CFH FBLN1 FBN1 SCUBE2 LAMC1 C4B LIMCH1	1.54e-07	193	92	7	30481fb01c7acf85beae10213f038da86bed6777
ToppCell	(1)_Osterolineage_cells\|World / Cell class and subclass of bone marrow stroma cells in homeostatis	CFH SLIT2 LRP4 TNFRSF19 LTBP1 LIMCH1 SP7	1.54e-07	193	92	7	035eeea9f77c4bf9cd85f07fa791b6c857be76b5
ToppCell	Children_(3_yrs)-Mesenchymal-matrix_fibroblast_1_cell-D139\|Children_(3_yrs) / Lineage, Cell type, age group and donor	SLIT2 FBLN1 FBN1 ADGRB3 LAMC1 LIMCH1 PLEKHH2	1.60e-07	194	92	7	e93de9428c986b8943fc169258847c650cfab0e5
ToppCell	Control-Fibroblasts-Intermediate_pathological_FB\|Control / group, cell type (main and fine annotations)	CFH SLIT2 FBLN1 FBN1 NALCN LTBP1 PLEKHH2	1.60e-07	194	92	7	03a269f75a481ea54aea8e6444605db8d6df493d
ToppCell	droplet-Heart-HEART_(ALL_MINUS_AORTA)-30m-Mesenchymal\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FBLN1 FBN1 PAM LAMC1 C4B LTBP1 ADAMTSL4	1.60e-07	194	92	7	2d0cff9dc538a14518741e2a96d9d78442c81a72
ToppCell	COVID-19-Heart-Fib_2\|Heart / Disease (COVID-19 only), tissue and cell type	CFH SLIT2 FBLN1 FBN1 ADGRB3 LAMC1 PLEKHH2	1.60e-07	194	92	7	d91c9f2ec47319051fc398320693fddbe8bbd4d6
ToppCell	LPS-antiTNF-Stromal_mesenchymal-Matrix_Fibroblast-MatrixFB\|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	SLIT2 FBLN1 FBN1 SCUBE2 ADGRB3 LIMCH1 PLEKHH2	1.60e-07	194	92	7	60622bd2f75bfe4c37f721cb12f03dab33f2f58d
ToppCell	PND07-28-samps-Mesenchymal\|PND07-28-samps / Age Group, Lineage, Cell class and subclass	SLIT2 FBLN1 FBN1 PAM LAMC1 LIMCH1 PLEKHH2	1.60e-07	194	92	7	68bcc1fe8dc8d5f23a12154fc9b41362fdef0b1d
ToppCell	COVID-19-Heart-Fib_1\|Heart / Disease (COVID-19 only), tissue and cell type	CFH SLIT2 FBLN1 FBN1 ADGRB3 LAMC1 PLEKHH2	1.65e-07	195	92	7	f423baa36ac7cdc383c033e35a7d17e6bf913323
ToppCell	LA-02._Fibroblast_II\|World / Chamber and Cluster_Paper	CFH SLIT2 FBLN1 FBN1 ADGRB3 LAMC1 PLEKHH2	1.65e-07	195	92	7	a78b605b49acd8c9d68716266ca269dafcd910b9
ToppCell	5'-Parenchyma_lung-Mesenchymal-Fibroblastic-fibroblastic_type_2-Alveolar_fibroblasts-Alveolar_fibroblasts_L.2.1.1.0\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	SLIT2 FBLN1 FBN1 ADGRB3 LAMC1 LIMCH1 PLEKHH2	1.65e-07	195	92	7	df409f94f4e83be89f7a608058ee07ce3ce3a149
ToppCell	COVID-19-Fibroblasts-Alveolar_FB\|COVID-19 / group, cell type (main and fine annotations)	SLIT2 FBLN1 FBN1 ADGRB3 LAMC1 LIMCH1 PLEKHH2	1.65e-07	195	92	7	603050beeb33c331d4b2e3fa46cae3f3e0e4bdc7
ToppCell	droplet-Bladder-nan-3m-Epithelial-luminal_bladder_epithelial_cell_(umbrella_cell)\|Bladder / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GDPD1 ATRN SCUBE2 WFDC2 PRRG4 PSAPL1 NOTCH1	1.65e-07	195	92	7	d6e2a5a15bea16de5f7ff09318c67d46ea923203
ToppCell	5'-Parenchyma_lung-Mesenchymal-Fibroblastic-fibroblastic_type_2-Alveolar_fibroblasts\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	SLIT2 FBLN1 FBN1 ADGRB3 LAMC1 LIMCH1 PLEKHH2	1.65e-07	195	92	7	4243190ad291d56694e2155954dbaa879c9d3844
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	CFH FBLN1 FBN1 NALCN LAMC3 LTBP1 PDZRN4	1.65e-07	195	92	7	edd4cd8402af81737b2074f9dce71cc6ab09be7e
ToppCell	3'-Parenchyma_lung-Mesenchymal-Fibroblastic-fibroblastic_type_2-Peribronchial_fibroblasts\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	CFH SLIT2 FBLN1 FBN1 LAMC1 LTBP1 PLEKHH2	1.65e-07	195	92	7	1236dc60288c7dd91868e86e9174a2dacd3b11b3
ToppCell	Bronchial-NucSeq-Stromal-Fibroblastic-Fibro_myofibroblast\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	CFH SLIT2 FBN1 NALCN ADGRB3 LTBP1 PLEKHH2	1.65e-07	195	92	7	f5e91ce20a7ce528dc4c1a968c7bf096bf45c528
Computational	Metal / Ca ion binding.	SLIT2 FBLN1 THBS4 FBN1 PAM LTBP1 RET	4.69e-06	133	55	7	MODULE_324
Computational	Complement.	CFH C4A C4B C8A	5.05e-06	23	55	4	MODULE_130
Computational	Neighborhood of HPX	CFH HGFAC C8A C8B F12	3.36e-05	73	55	5	CAR_HPX
Computational	Genes in the cancer module 58.	CFH C4B C8A	1.58e-04	21	55	3	MODULE_58
Computational	Neighborhood of IGFBP1	CFH HGFAC C8A F12	1.98e-04	57	55	4	CAR_IGFBP1
Computational	ECM and collagens.	SLIT2 FBLN1 FBN1 VWF DENND4B LTBP1	9.69e-04	225	55	6	MODULE_47
Computational	Trachea genes.	CFH SLIT2 FBLN1 VWF WFDC2 GCLC MUC5B LTBP1	1.14e-03	415	55	8	MODULE_6
Drug	Rgd Peptide	FBLN1 THBS4 FBN1 VWF RNGTT ADGRB3 LAMC1 LAMC3 ADAMTSL4	5.43e-07	239	92	9	CID000104802
Drug	AC1NE3ZR	CFH VWF C4A ABCC10	3.49e-06	26	92	4	CID004636208
Drug	I-hu	BSND CFH C4A	1.03e-05	11	92	3	CID009547901
Drug	geldanamycin; Down 200; 1uM; MCF7; HG-U133A	MST1R KLHL24 THBS4 RARA SCUBE2 RET C2CD5	1.30e-05	192	92	7	611_DN
Drug	Trioxsalen [3902-71-4]; Down 200; 17.6uM; PC3; HT_HG-U133A	FBLN1 KLHL24 FBN1 WFDC2 TRIM62 MYLIP USP48	1.44e-05	195	92	7	5736_DN
Drug	Fenbufen [36330-85-5]; Up 200; 15.8uM; MCF7; HT_HG-U133A	CCN6 ADAM19 ADGRB3 MUC5B LIMCH1 MUC5AC ADAMTSL4	1.54e-05	197	92	7	2308_UP
Drug	Dihydroergocristine mesylate [24730-10-7]; Down 200; 5.6uM; MCF7; HT_HG-U133A	RARA SCUBE2 ARHGEF10 TRIM62 ARIH2 LTBP1 USP48	1.59e-05	198	92	7	7034_DN
Drug	Grgds	FBLN1 THBS4 VWF LAMC1 ADAMTSL4	2.19e-05	83	92	5	CID000123811
Disease	Complement deficiency disease	CFH C4A C4B C8A C8B FCN3	6.58e-10	33	89	6	C0272242
Disease	Antibody Deficiency Syndrome	CFH C4A C8A C8B FCN3	1.34e-09	17	89	5	C0003257
Disease	Immunologic Deficiency Syndromes	CFH C4A C8A C8B FCN3	7.18e-09	23	89	5	C0021051
Disease	neurexophilin-1 measurement	CFH C8A C8B	1.47e-06	8	89	3	EFO_0008244
Disease	Ectopia Lentis	FBN1 ADAMTSL4	9.00e-06	2	89	2	C0013581
Disease	tumor necrosis factor receptor superfamily member 19 measurement	CFH TNFRSF19	9.00e-06	2	89	2	EFO_0020808
Disease	Ectopia lentis isolated	FBN1 ADAMTSL4	9.00e-06	2	89	2	C1851286
Disease	Familial ectopia lentis	FBN1 ADAMTSL4	9.00e-06	2	89	2	C2746069
Disease	Isolated ectopia lentis	FBN1 ADAMTSL4	9.00e-06	2	89	2	cv:C1851286
Disease	Ectopia lentis	FBN1 ADAMTSL4	9.00e-06	2	89	2	cv:C0013581
Disease	Neisseriaceae Infections	C8A C8B	2.69e-05	3	89	2	C0085396
Disease	Pachymeningitis	C8A C8B	2.69e-05	3	89	2	C0030167
Disease	Meningitis	C8A C8B	2.69e-05	3	89	2	C0025289
Disease	glycoprotein measurement	CFH HGFAC CMIP SCUBE2 F12	3.11e-05	119	89	5	EFO_0004555
Disease	cholangiocarcinoma (is_marker_for)	PRRG4 MUC5B MUC5AC NOTCH1	4.28e-05	64	89	4	DOID:4947 (is_marker_for)
Disease	toll-like receptor 2 measurement	CFH ABCC10	5.38e-05	4	89	2	EFO_0020777
Disease	septin-10 measurement	CFH C8B	5.38e-05	4	89	2	EFO_0802053
Disease	syntaxin-1a measurement	CFH HGFAC	8.94e-05	5	89	2	EFO_0020759
Disease	cyclin-H measurement	CFH C8B	8.94e-05	5	89	2	EFO_0801508
Disease	matrix extracellular phosphoglycoprotein measurement	CFH F12	8.94e-05	5	89	2	EFO_0020557
Disease	progonadoliberin-1 measurement	CFH F12	1.34e-04	6	89	2	EFO_0801924
Disease	CD63 antigen measurement	CFH F12	1.34e-04	6	89	2	EFO_0022033
Disease	NKG2-E type II integral membrane protein measurement	CFH C8B	1.34e-04	6	89	2	EFO_0801842
Disease	serine/threonine-protein kinase ULK3 measurement	CFH F12	1.34e-04	6	89	2	EFO_0803065
Disease	semenogelin-1 measurement	C8A C8B	1.34e-04	6	89	2	EFO_0802051
Disease	glucosidase 2 subunit beta measurement	CFH F12	1.34e-04	6	89	2	EFO_0801628
Disease	cadherin-15 measurement	CFH F12	1.87e-04	7	89	2	EFO_0020211
Disease	C-C motif chemokine 1 measurement	CFH C8B	1.87e-04	7	89	2	EFO_0008041
Disease	mesangial proliferative glomerulonephritis (biomarker_via_orthology)	FBN1 VWF	2.49e-04	8	89	2	DOID:4783 (biomarker_via_orthology)
Disease	sulfatase-modifying factor 1 measurement	C8A C8B	2.49e-04	8	89	2	EFO_0802098
Disease	Marfan Syndrome, Type I	FBN1 LAMC1	3.19e-04	9	89	2	C4721845
Disease	complement component C8 measurement	CFH C8B	3.19e-04	9	89	2	EFO_0008094
Disease	Fuchs endothelial corneal dystrophy	CFH LAMC1	3.98e-04	10	89	2	Orphanet_98974
Disease	bone morphogenetic protein 7 measurement	CFH F12	3.98e-04	10	89	2	EFO_0020187
Disease	transmembrane glycoprotein NMB measurement	CFH F12	3.98e-04	10	89	2	EFO_0008303
Disease	WNT1-inducible-signaling pathway protein 1 measurement	C8A C8B	3.98e-04	10	89	2	EFO_0008321
Disease	pulmonary fibrosis (biomarker_via_orthology)	VWF MUC5AC NOTCH1	4.69e-04	50	89	3	DOID:3770 (biomarker_via_orthology)
Disease	PR domain zinc finger protein 1 measurement	CFH BSN	4.86e-04	11	89	2	EFO_0801904
Disease	peptidyl-glycine alpha-amidating monooxygenase measurement	PAM F12	4.86e-04	11	89	2	EFO_0801871
Disease	pulmonary fibrosis	MUC5B MUC5AC	4.86e-04	11	89	2	EFO_0009448
Disease	Marfan Syndrome	FBN1 LAMC1	4.86e-04	11	89	2	C0024796
Disease	transmembrane protein 87B measurement	CFH F12	6.87e-04	13	89	2	EFO_0802158
Disease	idiopathic pulmonary fibrosis	MUC5B MUC5AC ABCC10	6.90e-04	57	89	3	EFO_0000768
Disease	membranous glomerulonephritis (biomarker_via_orthology)	CFH LRP2	8.00e-04	14	89	2	DOID:10976 (biomarker_via_orthology)
Disease	Kartagener syndrome (implicated_via_orthology)	SLIT2 ODAD2	8.00e-04	14	89	2	DOID:0050144 (implicated_via_orthology)
Disease	C-C motif chemokine 19 measurement	CFH BSN	8.00e-04	14	89	2	EFO_0008047
Disease	systemic lupus erythematosus (is_implicated_in)	CFH C4A C4B	8.82e-04	62	89	3	DOID:9074 (is_implicated_in)
Disease	mannan-binding lectin serine protease 1 measurement	CFH FCN3	9.21e-04	15	89	2	EFO_0008223
Disease	Proteinuria	VWF LRP2	9.21e-04	15	89	2	HP_0000093
Disease	coronary artery disease	BSND HGFAC DPYD CMIP ADAM19 DEFB127 LAMC1 PLEKHH2 BSN USP48 ABCC10	9.25e-04	1194	89	11	EFO_0001645
Disease	interstitial lung disease	MUC5B THSD7B MUC5AC	1.11e-03	67	89	3	EFO_0004244
Disease	venous thromboembolism, fibrinogen measurement	HGFAC VWF LRP4	1.11e-03	67	89	3	EFO_0004286, EFO_0004623
Disease	renal cell carcinoma (is_implicated_in)	HNF1B C4A C4B	1.20e-03	69	89	3	DOID:4450 (is_implicated_in)
Disease	prostate carcinoma	HNF1B SCUBE2 GCLC DENND4B LAMC1 ODAD2 PLEKHH2 BSN ADAMTSL4	1.47e-03	891	89	9	EFO_0001663
Disease	glaucoma (is_marker_for)	CFH MUC5AC	1.65e-03	20	89	2	DOID:1686 (is_marker_for)
Disease	glomerulonephritis (biomarker_via_orthology)	FBN1 LTBP1	1.65e-03	20	89	2	DOID:2921 (biomarker_via_orthology)
Disease	coagulation factor measurement	CFH VWF	1.65e-03	20	89	2	EFO_0004634
Disease	nephrosis (biomarker_via_orthology)	CFH LRP2	2.00e-03	22	89	2	DOID:2527 (biomarker_via_orthology)
Disease	mental or behavioural disorder	HNF1B ADAM19 RNGTT NALCN	2.14e-03	179	89	4	EFO_0000677
Disease	vitronectin measurement	CFH C8B	2.18e-03	23	89	2	EFO_0021843
Disease	venous thromboembolism, tissue plasminogen activator measurement	VWF LRP4	2.18e-03	23	89	2	EFO_0004286, EFO_0004791
Disease	sleep duration, low density lipoprotein cholesterol measurement	BSND ATXN7L2 GCLC	2.66e-03	91	89	3	EFO_0004611, EFO_0005271

Protein segments in the cluster

Peptide	Gene	Start	Entry
LGDTQNCQLRCRDRD	TMEM59L	36	Q9UK28
NCQLRCRDRDLGPQP	TMEM59L	41	Q9UK28
NECLGGVPECRDLQV	BACH1	261	O14867
ADCCRIQLQLPGKQD	ARHGEF10	806	O15013
QDVAGRGCCRDPNAQ	CCDC187	406	A0A096LP49
EVQGSQRCELNCRPR	ADAMTSL4	411	Q6UY14
CRAGIQERRRECDNP	C8A	551	P07357
CEQRAARVQQPDCRE	C4B	716	P0C0L5
GEEVRRCNEQRCPAP	ADGRB3	496	O60242
DAFRCRLRNCQDPIN	ADGRB3	1156	O60242
GTLCREQARQCDLPE	ADAM19	471	Q9H013
SLKEIRNGCQQPCDR	CMIP	351	Q8IY22
GQLCVADRENGRIQC	PAM	696	P19021
GLACGQDPELVRNIC	DPYD	681	Q12882
ELLQRPGNARCADCG	ADAP1	11	O75689
EPRARRVQCNRCNEV	ARIH2	241	O95376
CVAEDCNELPPRRNT	CFH	16	P08603
ECDLNRQCGVINPET	ATXN7L2	236	Q5T6C5
VCEQPLGLECRAQAQ	MUC5B	2351	Q9HC84
CIGNPDEDCERFRQL	PDZRN4	616	Q6ZMN7
VRCQQRNCIPIGEQL	PAAT	211	Q9H8K7
AICLICGDRQDLEQP	RARA	331	P10276
CIRVLCIGNENNQRA	ANKAR	846	Q7Z5J8
NLDREVCSRCGQPVD	DZIP1L	66	Q8IYY4
VNLLRCQEGPRNCRE	FCN3	81	O75636
CQEGPRNCRELLSQG	FCN3	86	O75636
GACGELRQPQDICRL	ABCC10	236	Q5T3U5
DPQIAICLDCLRNNG	PCGF5	136	Q86SE9
RQDVNECGQKPGLCR	NOTCH1	176	P46531
CERENTFECQNPRRC	LY6K	46	Q17RY6
PVGDCDFNVRLQCIE	RNGTT	371	O60942
CCGDNQAPVTEILRQ	NLRP10	226	Q86W26
EANEELRCAQLQPRG	HOOK2	416	Q96ED9
RNQECIALPENICGI	ATRN	776	O75882
ECQLCEVENRYQGNP	ATRN	1136	O75882
ERAICPLCQAELNVG	BSN	461	Q9UPA5
TQRGRCEDIDECLNP	LTBP1	991	Q14766
DRERLCGQAPQCVLA	PCDH8	91	O95206
NQIANELCECPELLG	GCLC	606	P48506
ECLENEKPDGNCRLN	DEFB105A	56	Q8NG35
ANGEDCLNQVCRRLG	MYLIP	21	Q8WY64
QRACQCEGKDNRIPL	GDPD1	121	Q8N9F7
PRECTESEFRCVNQQ	LRP2	3756	P98164
CSREEGLVCRNQDQQ	MUC5AC	1811	P98088
CSREEGLVCRNQDQQ	MUC5AC	4021	P98088
ICRVNEVPEALCENG	DEFB127	36	Q9H1M4
RLCNIEPDERCFLGN	HGFAC	276	Q04756
RGDPCNTICCREDLN	PLBD1	466	Q6P4A8
DGCSEEQLRQLCQRL	PLEKHH2	1306	Q8IVE3
IRDLCQARDCQNPNA	GPRC6A	426	Q5T6X5
LAPNGRNCQDIDECV	FBLN1	516	P23142
VCQRNCREPGDIFSE	CCN6	336	O95389
NCPCLRDLQPDQARR	FZD8	566	Q9H461
EQLDPCNCLGIQRFA	KLHL24	161	Q6TFL4
QEPQGCRCPLDRFQD	BSND	226	Q8WZ55
IDECLQNGRICNNGR	FBN1	531	P35555
LLDPRTQQECAQCGV	FNDC11	246	Q9BVV2
IIEDVQRLPGNDICC	ASAP1	441	Q9ULH1
RRLCLALDEPQLCNG	DENND4B	1236	O75064
RLCQCSDNIDPNAVG	LAMC1	826	P11047
RERCILCPNGTFQNE	SCUBE2	651	Q9NQ36
EQRLEENLPTRCGFC	C2CD5	451	Q86YS7
GRCVNRRLLCNGDND	C8B	131	P07358
AQRCGQGACRREDPQ	CTU2	441	Q2VPK5
QGACRREDPQACIEE	CTU2	446	Q2VPK5
CEQRAARVQQPDCRE	C4A	716	P0C0L4
TDVRIRNGLLNCNDC	LIMCH1	1056	Q9UPQ0
EECNRAECLQRGVSP	HNF1B	266	P35680
VLGQERRNHSCEPCQ	F12	426	P00748
LGVRQAQPLCEELCQ	RTBDN	106	Q9BSG5
RQAPEGALCQDCVRQ	PSAPL1	176	Q6NUJ1
VVGALGECCQERENR	ODAD2	776	Q5T2S8
APQEQEELLECRRRC	PPP1R3G	66	B7ZBB8
CVQDVAPNLQRCERL	NPB	86	Q8NG41
RGCKAERNCRNPELN	THBS4	416	P35443
NFPQLGLCRDQCQVD	WFDC2	86	Q14508
CPQSCEERNLRENGY	VWF	1126	P04275
VCDMCGNGRLEQRPE	SPIDR	796	Q14159
DCPNCQELERLGAAA	SP7	271	Q8TDD2
QNGAQCIVRINEPIC	SLIT2	1131	O94813
TPGNLERECNEELCN	PRRG4	61	Q9BZD6
QDINICPQDCLRGSI	RET	576	P07949
VCAQCLRNGQVIEPD	ZC3H7A	711	Q8IWR0
QRCENRLECNGAISA	ZNF415	56	Q09FC8
QQEFRDRSGNCVPCN	TNFRSF19	36	Q9NS68
ADEVNCPICQGTLRE	TRIM10	11	Q9UDY6
EQLRECGFLRTPEQC	ZKSCAN2	536	Q63HK3
CHQQLQELEEGCRPE	TEX28	116	O15482
EACIVEGELLQQCPR	THSD7B	386	Q9C0I4
CPECREGLLCQQQRD	USP48	841	Q86UV5
EEDCRLNGPQKQDLC	ZNF425	111	Q6IV72
RQEAQGARDCPECRR	TRIM62	41	Q9BVG3
ESRCERQLPEQQLCR	MST1R	811	Q04912
LQAVDNEGNPLCLRC	ZRANB3	901	Q5FWF4
RPCESNECGNAIRQN	ZNF554	271	Q86TJ5
TLIQGLNECCNVRPE	AK7	691	Q96M32
KENVEGNLCDRCRPG	LAMC3	451	Q9Y6N6
QQNCRPRTGEENCNV	LRP4	346	O75096
CNDPNIIRREDCNGI	NALCN	1046	Q8IZF0