Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	polyubiquitin modification-dependent protein binding	EPS15 UBQLN2 UBQLN1 UBQLN4	2.04e-06	59	31	4	GO:0031593
GeneOntologyMolecularFunction	modification-dependent protein binding	EPS15 UBQLN2 UBQLN1 UBQLN4	2.78e-04	206	31	4	GO:0140030
GeneOntologyMolecularFunction	nuclear retinoid X receptor binding	NCOA1 NCOA6	5.78e-04	23	31	2	GO:0046965
GeneOntologyBiologicalProcess	cytoskeleton-dependent cytokinesis	SEPTIN1 KIF4A KIF4B SEPTIN2	3.79e-05	127	31	4	GO:0061640
GeneOntologyBiologicalProcess	mitotic spindle midzone assembly	KIF4A KIF4B	1.19e-04	11	31	2	GO:0051256
GeneOntologyBiologicalProcess	mitotic spindle elongation	KIF4A KIF4B	1.43e-04	12	31	2	GO:0000022
GeneOntologyBiologicalProcess	spindle midzone assembly	KIF4A KIF4B	1.97e-04	14	31	2	GO:0051255
GeneOntologyBiologicalProcess	spindle elongation	KIF4A KIF4B	1.97e-04	14	31	2	GO:0051231
GeneOntologyBiologicalProcess	cytokinesis	SEPTIN1 KIF4A KIF4B SEPTIN2	2.37e-04	204	31	4	GO:0000910
GeneOntologyCellularComponent	septin complex	SEPTIN1 SEPTIN2	1.92e-04	14	31	2	GO:0031105
GeneOntologyCellularComponent	septin ring	SEPTIN1 SEPTIN2	1.92e-04	14	31	2	GO:0005940
GeneOntologyCellularComponent	septin cytoskeleton	SEPTIN1 SEPTIN2	2.52e-04	16	31	2	GO:0032156
GeneOntologyCellularComponent	midbody	SEPTIN1 KIF4A KIF4B SEPTIN2	3.11e-04	222	31	4	GO:0030496
GeneOntologyCellularComponent	autophagosome	UBQLN2 UBQLN1 UBQLN4	7.20e-04	119	31	3	GO:0005776
GeneOntologyCellularComponent	clathrin vesicle coat	EPS15 CLINT1	1.45e-03	38	31	2	GO:0030125
GeneOntologyCellularComponent	aggresome	EPS15 UBQLN1	1.60e-03	40	31	2	GO:0016235
GeneOntologyCellularComponent	transcription regulator complex	NCOA1 BCL9L NCOA6 ZFHX3 DEPDC1	1.70e-03	596	31	5	GO:0005667
MousePheno	increased dendritic spine number	KIF4A KIF4B	1.08e-05	3	27	2	MP:0021019
MousePheno	decreased brain size	GPC1 KIF4A KIF4B PFDN5 CHD7 UBQLN4	1.71e-05	295	27	6	MP:0000774
MousePheno	dilated third ventricle	NCOA6 PFDN5 CHD7	3.69e-05	34	27	3	MP:0000827
MousePheno	abnormal brain size	GPC1 KIF4A KIF4B PFDN5 CHD7 UBQLN4	6.57e-05	375	27	6	MP:0000771
MousePheno	small hippocampus	KIF4A KIF4B CHD7	9.23e-05	46	27	3	MP:0008283
MousePheno	behavioral developmental delay	KIF4A KIF4B	9.99e-05	8	27	2	MP:0021165
MousePheno	abnormal hippocampus size	KIF4A KIF4B CHD7	1.58e-04	55	27	3	MP:0008281
MousePheno	abnormal dendritic spine number	KIF4A KIF4B	1.60e-04	10	27	2	MP:0021017
Domain	Ubiquilin	UBQLN2 UBQLN1 UBQLN4	8.25e-08	6	31	3	IPR015496
Domain	STI1_HS-bd	UBQLN2 UBQLN1 UBQLN4	4.93e-07	10	31	3	IPR006636
Domain	STI1	UBQLN2 UBQLN1 UBQLN4	4.93e-07	10	31	3	SM00727
Domain	Ubiquilin-1/2	UBQLN2 UBQLN1	2.67e-06	2	31	2	IPR028430
Domain	UBA-like	SMARCAD1 UBQLN2 UBQLN1 UBQLN4	3.68e-06	64	31	4	IPR009060
Domain	6-PGluconate_DH_C-like	UBQLN2 UBQLN1 UBQLN4	3.94e-06	19	31	3	IPR008927
Domain	UBA	UBQLN2 UBQLN1 UBQLN4	1.63e-05	30	31	3	SM00165
Domain	UBA	UBQLN2 UBQLN1 UBQLN4	2.85e-05	36	31	3	PF00627
Domain	UBIQUITIN_1	UBQLN2 UBQLN1 UBQLN4	3.10e-05	37	31	3	PS00299
Domain	UBQ	UBQLN2 UBQLN1 UBQLN4	4.88e-05	43	31	3	SM00213
Domain	UBA	UBQLN2 UBQLN1 UBQLN4	5.24e-05	44	31	3	IPR015940
Domain	UBA	UBQLN2 UBQLN1 UBQLN4	6.39e-05	47	31	3	PS50030
Domain	ubiquitin	UBQLN2 UBQLN1 UBQLN4	6.39e-05	47	31	3	PF00240
Domain	UBIQUITIN_2	UBQLN2 UBQLN1 UBQLN4	9.70e-05	54	31	3	PS50053
Domain	Ubiquitin_dom	UBQLN2 UBQLN1 UBQLN4	1.20e-04	58	31	3	IPR000626
Domain	Septin	SEPTIN1 SEPTIN2	2.06e-04	13	31	2	PF00735
Domain	G_SEPTIN_dom	SEPTIN1 SEPTIN2	2.06e-04	13	31	2	IPR030379
Domain	G_SEPTIN	SEPTIN1 SEPTIN2	2.06e-04	13	31	2	PS51719
Domain	Prefoldin	KIF4A EPS15 PFDN5	2.29e-04	72	31	3	IPR009053
Domain	Septin	SEPTIN1 SEPTIN2	2.40e-04	14	31	2	IPR016491
Domain	P-loop_NTPase	SEPTIN1 KIF4A KIF4B SMARCAD1 CHD7 RHOBTB1 SEPTIN2	3.92e-04	848	31	7	IPR027417
Domain	ZnF_U1	ZFHX3 ZFHX4	1.05e-03	29	31	2	SM00451
Domain	Znf_U1	ZFHX3 ZFHX4	1.05e-03	29	31	2	IPR003604
Domain	SNF2_N	SMARCAD1 CHD7	1.28e-03	32	31	2	PF00176
Domain	SNF2_N	SMARCAD1 CHD7	1.28e-03	32	31	2	IPR000330
Domain	Kinesin_motor_CS	KIF4A KIF4B	2.10e-03	41	31	2	IPR019821
Domain	Kinesin-like_fam	KIF4A KIF4B	2.31e-03	43	31	2	IPR027640
Domain	KINESIN_MOTOR_1	KIF4A KIF4B	2.42e-03	44	31	2	PS00411
Domain	-	KIF4A KIF4B	2.42e-03	44	31	2	3.40.850.10
Domain	Kinesin_motor_dom	KIF4A KIF4B	2.42e-03	44	31	2	IPR001752
Domain	Kinesin	KIF4A KIF4B	2.42e-03	44	31	2	PF00225
Domain	KISc	KIF4A KIF4B	2.42e-03	44	31	2	SM00129
Domain	KINESIN_MOTOR_2	KIF4A KIF4B	2.42e-03	44	31	2	PS50067
Domain	Ubiquitin-rel_dom	UBQLN2 UBQLN1 UBQLN4	3.45e-03	184	31	3	IPR029071
Domain	RHOGAP	DEPDC1 ARHGAP18	5.04e-03	64	31	2	PS50238
Domain	RhoGAP_dom	DEPDC1 ARHGAP18	5.04e-03	64	31	2	IPR000198
Domain	-	DEPDC1 ARHGAP18	5.04e-03	64	31	2	1.10.555.10
Domain	-	SEPTIN1 SMARCAD1 CHD7 RHOBTB1 SEPTIN2	7.19e-03	746	31	5	3.40.50.300
Domain	Rho_GTPase_activation_prot	DEPDC1 ARHGAP18	9.34e-03	88	31	2	IPR008936
Pathway	REACTOME_RORA_ACTIVATES_GENE_EXPRESSION	NCOA1 NCOA6	4.18e-04	18	24	2	M26942
Pathway	REACTOME_MEMBRANE_TRAFFICKING	KIF4A EPS15 KIF4B CLINT1 UBQLN2 UBQLN1	5.25e-04	630	24	6	M11480
Pathway	REACTOME_VESICLE_MEDIATED_TRANSPORT	KIF4A EPS15 KIF4B CLINT1 UBQLN2 UBQLN1	5.95e-04	645	24	6	MM15232
Pathway	REACTOME_CARGO_RECOGNITION_FOR_CLATHRIN_MEDIATED_ENDOCYTOSIS	EPS15 UBQLN2 UBQLN1	6.67e-04	102	24	3	MM15498
Pathway	REACTOME_CARGO_RECOGNITION_FOR_CLATHRIN_MEDIATED_ENDOCYTOSIS	EPS15 UBQLN2 UBQLN1	7.25e-04	105	24	3	M27752
Pubmed	Herp enhances ER-associated protein degradation by recruiting ubiquilins.	UBQLN2 UBQLN1 UBQLN4	2.56e-09	4	31	3	18307982
Pubmed	Proteome-scale mapping of binding sites in the unstructured regions of the human proteome.	SETD1A EPS15 NCOA6 SMARCAD1 CHD7 CLINT1 UBQLN2 UBQLN1	3.15e-09	430	31	8	35044719
Pubmed	Mapping the Ku Interactome Using Proximity-Dependent Biotin Identification in Human Cells.	SUGP1 KIF4A NCOA6 ZFHX3 SCAF11 CHD7 SEPTIN2	4.88e-09	283	31	7	30585729
Pubmed	RTL8 promotes nuclear localization of UBQLN2 to subnuclear compartments associated with protein quality control.	UBQLN2 UBQLN1 UBQLN4	1.28e-08	6	31	3	35247097
Pubmed	Interaction network of human early embryonic transcription factors.	NCOA1 BCL9L SETD1A NCOA6 ZFHX3 CHD7 ZFHX4	2.15e-08	351	31	7	38297188
Pubmed	The ubiquitin-like protein PLIC-2 is a negative regulator of G protein-coupled receptor endocytosis.	EPS15 UBQLN2 UBQLN1	2.24e-08	7	31	3	18199683
Pubmed	Structure of hRpn10 Bound to UBQLN2 UBL Illustrates Basis for Complementarity between Shuttle Factors and Substrates at the Proteasome.	UBQLN2 UBQLN1 UBQLN4	2.24e-08	7	31	3	30664872
Pubmed	Ubiquilin4 is an adaptor protein that recruits Ubiquilin1 to the autophagy machinery.	UBQLN2 UBQLN1 UBQLN4	3.58e-08	8	31	3	23459205
Pubmed	Crosstalk between Lys63- and Lys11-polyubiquitin signaling at DNA damage sites is driven by Cezanne.	EPS15 UBQLN2 UBQLN1 UBQLN4	1.16e-07	50	31	4	31699778
Pubmed	Proximity-dependent Mapping of the Androgen Receptor Identifies Kruppel-like Factor 4 as a Functional Partner.	SUGP1 NCOA1 KIF4A BCL9L NCOA6 CHD7	1.24e-07	268	31	6	33640491
Pubmed	UBQLN2 Mediates Autophagy-Independent Protein Aggregate Clearance by the Proteasome.	UBQLN2 UBQLN1 UBQLN4	1.82e-07	13	31	3	27477512
Pubmed	PRISMA and BioID disclose a motifs-based interactome of the intrinsically disordered transcription factor C/EBPα.	SUGP1 NCOA1 KIF4A NCOA6 PFDN5 CHD7 CLINT1 UBQLN1 SEPTIN2	3.38e-07	1103	31	9	34189442
Pubmed	KIF4 regulates neuronal morphology and seizure susceptibility via the PARP1 signaling pathway.	KIF4A KIF4B	7.69e-07	2	31	2	36482480
Pubmed	The mouse ZFH-4 protein contains four homeodomains and twenty-two zinc fingers.	ZFHX3 ZFHX4	7.69e-07	2	31	2	10873665
Pubmed	KIF4 regulates midzone length during cytokinesis.	KIF4A KIF4B	7.69e-07	2	31	2	21565503
Pubmed	Whole genome expression microarray reveals novel roles for Kif4 in monocyte/macrophage cells.	KIF4A KIF4B	7.69e-07	2	31	2	31486502
Pubmed	Identification of septins in neurofibrillary tangles in Alzheimer's disease.	SEPTIN1 SEPTIN2	7.69e-07	2	31	2	9811347
Pubmed	Assignment of the kinesin family member 4 genes (KIF4A and KIF4B) to human chromosome bands Xq13.1 and 5q33.1 by in situ hybridization.	KIF4A KIF4B	7.69e-07	2	31	2	10773663
Pubmed	A novel microtubule-based motor protein (KIF4) for organelle transports, whose expression is regulated developmentally.	KIF4A KIF4B	7.69e-07	2	31	2	7929562
Pubmed	DEPDC1 and KIF4A synergistically inhibit the malignant biological behavior of osteosarcoma cells through Hippo signaling pathway.	KIF4A DEPDC1	7.69e-07	2	31	2	36849972
Pubmed	The multiple functions of kinesin-4 family motor protein KIF4 and its clinical potential.	KIF4A KIF4B	7.69e-07	2	31	2	30081192
Pubmed	Missense Pathogenic variants in KIF4A Affect Dental Morphogenesis Resulting in X-linked Taurodontism, Microdontia and Dens-Invaginatus.	KIF4A KIF4B	7.69e-07	2	31	2	31616463
Pubmed	Structural basis for the ATP-induced isomerization of kinesin.	KIF4A KIF4B	7.69e-07	2	31	2	23500491
Pubmed	Chromokinesin Kif4 promotes proper anaphase in mouse oocyte meiosis.	KIF4A KIF4B	7.69e-07	2	31	2	31067151
Pubmed	Kif4 regulates the expression of VEGFR1 through the PI3K/Akt signaling pathway in RAW264.7 monocytes/macrophages.	KIF4A KIF4B	7.69e-07	2	31	2	28350061
Pubmed	Binding of murine leukemia virus Gag polyproteins to KIF4, a microtubule-based motor protein.	KIF4A KIF4B	7.69e-07	2	31	2	9658142
Pubmed	Cellular motor protein KIF-4 associates with retroviral Gag.	KIF4A KIF4B	7.69e-07	2	31	2	10559369
Pubmed	A new Drosophila model of Ubiquilin knockdown shows the effect of impaired proteostasis on locomotive and learning abilities.	UBQLN2 UBQLN1	7.69e-07	2	31	2	29247619
Pubmed	Kif4 interacts with EB1 and stabilizes microtubules downstream of Rho-mDia in migrating fibroblasts.	KIF4A KIF4B	7.69e-07	2	31	2	24658398
Pubmed	Towards a molecular understanding of the overlapping and distinct roles of UBQLN1 and UBQLN2 in lung cancer progression and metastasis.	UBQLN2 UBQLN1	7.69e-07	2	31	2	35063704
Pubmed	WDR76 Co-Localizes with Heterochromatin Related Proteins and Rapidly Responds to DNA Damage.	KIF4A SETD1A SCAF11 CHD7 UBQLN1 UBQLN4	1.18e-06	394	31	6	27248496
Pubmed	Proximity-dependent biotin identification (BioID) reveals a dynamic LSD1-CoREST interactome during embryonic stem cell differentiation.	EPS15 ZFHX3 CHD7 ZFHX4 LUC7L2 UBQLN4	1.66e-06	418	31	6	34709266
Pubmed	Identification of the human homologue of mouse KIF4, a kinesin superfamily motor protein.	KIF4A KIF4B	2.31e-06	3	31	2	10978527
Pubmed	KIF4 motor regulates activity-dependent neuronal survival by suppressing PARP-1 enzymatic activity.	KIF4A KIF4B	2.31e-06	3	31	2	16630823
Pubmed	Ubiquilin functions in autophagy and is degraded by chaperone-mediated autophagy.	UBQLN2 UBQLN1	2.31e-06	3	31	2	20529957
Pubmed	CircKIF4A enhances osteosarcoma proliferation and metastasis by sponging MiR-515-5p and upregulating SLC7A11.	KIF4A KIF4B	2.31e-06	3	31	2	35579738
Pubmed	Tumor formation via loss of a molecular motor protein.	KIF4A KIF4B	2.31e-06	3	31	2	16890532
Pubmed	Ubiquitin receptor proteins hHR23a and hPLIC2 interact.	UBQLN2 UBQLN1	2.31e-06	3	31	2	17098253
Pubmed	KIF4 mediates anterograde translocation and positioning of ribosomal constituents to axons.	KIF4A KIF4B	2.31e-06	3	31	2	19158085
Pubmed	Human transcription factor protein interaction networks.	SUGP1 NCOA1 BCL9L SETD1A NCOA6 ZFHX3 SCAF11 CHD7 ZFHX4	2.89e-06	1429	31	9	35140242
Pubmed	A high-throughput approach for measuring temporal changes in the interactome.	GPC1 EPS15 SMARCAD1 PFDN5 CLINT1 UBQLN2 UBQLN1 LUC7L2 SEPTIN2	3.35e-06	1455	31	9	22863883
Pubmed	Wnt signalling regulates paxillin ubiquitination essential for mesodermal cell motility.	UBQLN2 UBQLN1 UBQLN4	3.44e-06	33	31	3	17558393
Pubmed	Expression profiling the human septin gene family.	SEPTIN1 SEPTIN2	4.61e-06	4	31	2	15915442
Pubmed	Kinesin KIF4 regulates intracellular trafficking and stability of the human immunodeficiency virus type 1 Gag polyprotein.	KIF4A KIF4B	4.61e-06	4	31	2	18684836
Pubmed	Characterization of a gamma-adaptin ear-binding motif in enthoprotin.	EPS15 CLINT1	4.61e-06	4	31	2	14675752
Pubmed	PLIC proteins or ubiquilins regulate autophagy-dependent cell survival during nutrient starvation.	UBQLN2 UBQLN1	4.61e-06	4	31	2	19148225
Pubmed	Kif4 Is Essential for Mouse Oocyte Meiosis.	KIF4A KIF4B	4.61e-06	4	31	2	28125646
Pubmed	Behavioral abnormalities observed in Zfhx2-deficient mice.	ZFHX3 ZFHX4	4.61e-06	4	31	2	23300874
Pubmed	UBQLN2 undergoes a reversible temperature-induced conformational switch that regulates binding with HSPA1B: ALS/FTD mutations cripple the switch but do not destroy HSPA1B binding.	UBQLN2 UBQLN1	4.61e-06	4	31	2	36423739
Pubmed	E6AP AZUL interaction with UBQLN1/2 in cells, condensates, and an AlphaFold-NMR integrated structure.	UBQLN2 UBQLN1	4.61e-06	4	31	2	36827983
Pubmed	Dimerization of ubiquilin is dependent upon the central region of the protein: evidence that the monomer, but not the dimer, is involved in binding presenilins.	UBQLN2 UBQLN1	4.61e-06	4	31	2	16813565
Pubmed	A CRISPR-based screen for Hedgehog signaling provides insights into ciliary function and ciliopathies.	KIF4A EPS15 KIF4B C5 RUFY3	5.00e-06	284	31	5	29459677
Pubmed	Nuclear export of ubiquitinated proteins via the UBIN-POST system.	UBQLN2 UBQLN1 UBQLN4	5.30e-06	38	31	3	29666234
Pubmed	Ubiquilin regulates presenilin endoproteolysis and modulates gamma-secretase components, Pen-2 and nicastrin.	UBQLN2 UBQLN1	7.68e-06	5	31	2	15975090
Pubmed	A draft of the human septin interactome.	SEPTIN1 SEPTIN2	7.68e-06	5	31	2	21082023
Pubmed	Ubiquitin-related proteins regulate interaction of vimentin intermediate filaments with the plasma membrane.	UBQLN2 UBQLN1	7.68e-06	5	31	2	10549293
Pubmed	The UBL domain of PLIC-1 regulates aggresome formation.	EPS15 UBQLN1	7.68e-06	5	31	2	17082820
Pubmed	Structural studies of the interaction between ubiquitin family proteins and proteasome subunit S5a.	UBQLN2 UBQLN1	7.68e-06	5	31	2	11827521
Pubmed	Ubiquilin recruits Eps15 into ubiquitin-rich cytoplasmic aggregates via a UIM-UBL interaction.	EPS15 UBQLN1	7.68e-06	5	31	2	16159959
Pubmed	Functional proteomics mapping of a human signaling pathway.	EPS15 NCOA6 UBQLN2 UBQLN1 LUC7L2 UBQLN4	1.20e-05	591	31	6	15231748
Pubmed	The hPLIC proteins may provide a link between the ubiquitination machinery and the proteasome.	UBQLN2 UBQLN1	1.61e-05	7	31	2	10983987
Pubmed	Unbiased screen reveals ubiquilin-1 and -2 highly associated with huntingtin inclusions.	UBQLN2 UBQLN1	1.61e-05	7	31	2	23774650
Pubmed	Ubiquilins Chaperone and Triage Mitochondrial Membrane Proteins for Degradation.	UBQLN2 UBQLN1	1.61e-05	7	31	2	27345149
Pubmed	Unusual chromatin status and organization of the inactive X chromosome in murine trophoblast giant cells.	KIF4A KIF4B	1.61e-05	7	31	2	23362347
Pubmed	Cross-species divergence of the major recognition pathways of ubiquitylated substrates for ubiquitin/26S proteasome-mediated proteolysis.	UBQLN2 UBQLN1	1.61e-05	7	31	2	20059542
Pubmed	Induction of nuclear translocation of constitutive androstane receptor by peroxisome proliferator-activated receptor alpha synthetic ligands in mouse liver.	NCOA1 NCOA6	1.61e-05	7	31	2	17962186
Pubmed	Kinesin family in murine central nervous system.	KIF4A KIF4B	1.61e-05	7	31	2	1447303
Pubmed	Genetic mapping in the mouse of Kif4, a gene encoding a kinesin-like motor protein.	KIF4A KIF4B	1.61e-05	7	31	2	9196009
Pubmed	Highly homologous HERC proteins localize to endosomes and exhibit specific interactions with hPLIC and Nm23B.	UBQLN2 UBQLN1	1.61e-05	7	31	2	18535780
Pubmed	A regulated interaction with the UIM protein Eps15 implicates parkin in EGF receptor trafficking and PI(3)K-Akt signalling.	EPS15 UBQLN1	2.15e-05	8	31	2	16862145
Pubmed	NCOA6 differentially regulates the expression of the CYP2C9 and CYP3A4 genes.	NCOA1 NCOA6	2.15e-05	8	31	2	21292004
Pubmed	EpsinR: an AP1/clathrin interacting protein involved in vesicle trafficking.	EPS15 CLINT1	2.76e-05	9	31	2	12538641
Pubmed	Clint: a novel clathrin-binding ENTH-domain protein at the Golgi.	EPS15 CLINT1	2.76e-05	9	31	2	12429846
Pubmed	Autoubiquitination of the 26S proteasome on Rpn13 regulates breakdown of ubiquitin conjugates.	UBQLN2 UBQLN1 UBQLN4	2.82e-05	66	31	3	24811749
Pubmed	Contribution of epigenetic landscapes and transcription factors to X-chromosome reactivation in the inner cell mass.	KIF4A KIF4B	3.44e-05	10	31	2	29101321
Pubmed	Functional analysis of human microtubule-based motor proteins, the kinesins and dyneins, in mitosis/cytokinesis using RNA interference.	KIF4A KIF4B	4.21e-05	11	31	2	15843429
Pubmed	The aftiphilin/p200/gamma-synergin complex.	EPS15 CLINT1	4.21e-05	11	31	2	15758025
Pubmed	Activating protein-1, nuclear factor-kappaB, and serum response factor as novel target molecules of the cancer-amplified transcription coactivator ASC-2.	NCOA1 NCOA6	4.21e-05	11	31	2	10847592
Pubmed	Multiple developmental defects derived from impaired recruitment of ASC-2 to nuclear receptors in mice: implication for posterior lenticonus with cataract.	NCOA1 NCOA6	4.21e-05	11	31	2	12446761
Pubmed	The Hippocampal Response to Acute Corticosterone Elevation Is Altered in a Mouse Model for Angelman Syndrome.	NCOA1 NCOA6	4.21e-05	11	31	2	36613751
Pubmed	Characterization of nuclear factors modulating the apolipoprotein D promoter during growth arrest: implication of PARP-1, APEX-1 and ERK1/2 catalytic activities.	KIF4A KIF4B	4.21e-05	11	31	2	20493910
Pubmed	Agonist-specific Protein Interactomes of Glucocorticoid and Androgen Receptor as Revealed by Proximity Mapping.	NCOA1 NCOA6 CHD7	4.66e-05	78	31	3	28611094
Pubmed	Amyloid Precursor Protein (APP) May Act as a Substrate and a Recognition Unit for CRL4CRBN and Stub1 E3 Ligases Facilitating Ubiquitination of Proteins Involved in Presynaptic Functions and Neurodegeneration.	UBQLN2 UBQLN1 UBQLN4	4.84e-05	79	31	3	27325702
Pubmed	Identification of a transcriptionally active peroxisome proliferator-activated receptor alpha -interacting cofactor complex in rat liver and characterization of PRIC285 as a coactivator.	NCOA1 NCOA6	5.05e-05	12	31	2	12189208
Pubmed	PAQR9 Modulates BAG6-mediated protein quality control of mislocalized membrane proteins.	UBQLN2 UBQLN1	5.05e-05	12	31	2	31904842
Pubmed	Activating signal cointegrator 2 belongs to a novel steady-state complex that contains a subset of trithorax group proteins.	NCOA1 NCOA6	6.95e-05	14	31	2	12482968
Pubmed	Identification of protein arginine methyltransferase 2 as a coactivator for estrogen receptor alpha.	NCOA1 NCOA6	6.95e-05	14	31	2	12039952
Pubmed	A nuclear factor, ASC-2, as a cancer-amplified transcriptional coactivator essential for ligand-dependent transactivation by nuclear receptors in vivo.	NCOA1 NCOA6	8.02e-05	15	31	2	10567404
Pubmed	Global proteomics of Ubqln2-based murine models of ALS.	EPS15 CLINT1 UBQLN2 UBQLN1	8.31e-05	261	31	4	33277362
Pubmed	SET1 and p300 act synergistically, through coupled histone modifications, in transcriptional activation by p53.	SETD1A NCOA6	9.16e-05	16	31	2	23870121
Pubmed	Localization of septin proteins in the mouse cochlea.	SEPTIN1 SEPTIN2	9.16e-05	16	31	2	22575789
Pubmed	H3K4 mono- and di-methyltransferase MLL4 is required for enhancer activation during cell differentiation.	SETD1A NCOA6	9.16e-05	16	31	2	24368734
Pubmed	Prediction of the coding sequences of mouse homologues of KIAA gene: III. the complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.	SETD1A NCOA6 SCAF11 RUFY3 SEPTIN2	9.79e-05	529	31	5	14621295
Pubmed	PTIP associates with MLL3- and MLL4-containing histone H3 lysine 4 methyltransferase complex.	SETD1A NCOA6	1.17e-04	18	31	2	17500065
Pubmed	Early embryonic lethality of mice with disrupted transcription cofactor PIMT/NCOA6IP/Tgs1 gene.	NCOA1 NCOA6	1.30e-04	19	31	2	22982455
Pubmed	Resetting the epigenetic balance of Polycomb and COMPASS function at enhancers for cancer therapy.	SETD1A NCOA6	1.45e-04	20	31	2	29785026
Pubmed	T0070907, a selective ligand for peroxisome proliferator-activated receptor gamma, functions as an antagonist of biochemical and cellular activities.	NCOA1 NCOA6	1.45e-04	20	31	2	11877444
Pubmed	The histone demethylase Kdm6b regulates subtype diversification of mouse spinal motor neurons during development.	ZFHX3 ZFHX4	1.45e-04	20	31	2	35177643
Pubmed	Direct interaction between hnRNP-M and CDC5L/PLRG1 proteins affects alternative splice site choice.	KIF4A SMARCAD1 CHD7 CLINT1 LUC7L2	1.53e-04	582	31	5	20467437
Pubmed	Nuclear receptor-coregulator interaction profiling identifies TRIP3 as a novel peroxisome proliferator-activated receptor gamma cofactor.	NCOA1 NCOA6	1.60e-04	21	31	2	19596656
Interaction	PAX9 interactions	BCL9L NCOA6 ZFHX3 PFDN5 CHD7 ZFHX4	4.14e-08	130	31	6	int:PAX9
Interaction	EGR2 interactions	NCOA1 BCL9L NCOA6 ZFHX3 CHD7 ZFHX4	2.11e-07	171	31	6	int:EGR2
Interaction	PLAAT3 interactions	UBQLN2 UBQLN1 UBQLN4	5.39e-07	11	31	3	int:PLAAT3
Interaction	ZG16 interactions	UBQLN2 UBQLN1 UBQLN4	7.18e-07	12	31	3	int:ZG16
Interaction	XRCC6 interactions	SUGP1 KIF4A NCOA6 ZFHX3 SCAF11 SMARCAD1 CHD7 UBQLN2 PLGRKT SEPTIN2	7.49e-07	928	31	10	int:XRCC6
Interaction	SERPINI2 interactions	UBQLN2 UBQLN1 UBQLN4	2.65e-06	18	31	3	int:SERPINI2
Interaction	SRGN interactions	UBQLN2 UBQLN1 UBQLN4	3.69e-06	20	31	3	int:SRGN
Interaction	RSRC2 interactions	PFDN5 UBQLN2 UBQLN1 UBQLN4	5.16e-06	75	31	4	int:RSRC2
Interaction	SP7 interactions	SUGP1 NCOA1 BCL9L NCOA6 CHD7 ZFHX4	6.01e-06	304	31	6	int:SP7
Interaction	SMIM2 interactions	UBQLN2 UBQLN1	6.86e-06	3	31	2	int:SMIM2
Interaction	DEFB115 interactions	UBQLN2 UBQLN1	6.86e-06	3	31	2	int:DEFB115
Interaction	SLC5A10 interactions	UBQLN1 UBQLN4	6.86e-06	3	31	2	int:SLC5A10
Interaction	SCG5 interactions	UBQLN2 UBQLN1 UBQLN4	8.37e-06	26	31	3	int:SCG5
Interaction	PPIC interactions	UBQLN2 UBQLN1 UBQLN4	8.37e-06	26	31	3	int:PPIC
Interaction	NSFL1C interactions	GPC1 UBQLN2 UBQLN1 RHOBTB1 UBQLN4	1.04e-05	192	31	5	int:NSFL1C
Interaction	KLHL42 interactions	PFDN5 UBQLN2 UBQLN1 UBQLN4	1.11e-05	91	31	4	int:KLHL42
Interaction	MDK interactions	SETD1A UBQLN2 UBQLN1 UBQLN4	1.11e-05	91	31	4	int:MDK
Interaction	STMN1 interactions	GPC1 KIF4B UBQLN1 UBQLN4 SEPTIN2	1.12e-05	195	31	5	int:STMN1
Interaction	OR4N2 interactions	UBQLN2 UBQLN1 SLC12A7	1.17e-05	29	31	3	int:OR4N2
Interaction	ERP27 interactions	UBQLN2 UBQLN1 UBQLN4	1.30e-05	30	31	3	int:ERP27
Interaction	FEV interactions	SETD1A NCOA6 ZFHX3 CHD7 ZFHX4	1.36e-05	203	31	5	int:FEV
Interaction	CLINT1 interactions	EPS15 PFDN5 CLINT1 UBQLN2 ARHGAP18	1.49e-05	207	31	5	int:CLINT1
Interaction	NME3 interactions	UBQLN2 UBQLN1 PLGRKT UBQLN4	1.62e-05	100	31	4	int:NME3
Interaction	CSTF2T interactions	CLINT1 UBQLN2 UBQLN1 UBQLN4	1.96e-05	105	31	4	int:CSTF2T
Interaction	EPS15 interactions	EPS15 CLINT1 UBQLN2 UBQLN1 ARHGAP18	2.00e-05	220	31	5	int:EPS15
Interaction	MIEF2 interactions	UBQLN2 UBQLN1 UBQLN4	2.09e-05	35	31	3	int:MIEF2
Interaction	GUCA2B interactions	UBQLN2 UBQLN1	2.28e-05	5	31	2	int:GUCA2B
Interaction	TBR1 interactions	BCL9L ZFHX3 CHD7 ZFHX4	2.62e-05	113	31	4	int:TBR1
Interaction	ITPRIPL1 interactions	UBQLN2 UBQLN1 UBQLN4	3.13e-05	40	31	3	int:ITPRIPL1
Interaction	ELK3 interactions	SETD1A PFDN5 CHD7 ZFHX4	3.32e-05	120	31	4	int:ELK3
Interaction	OR6T1 interactions	UBQLN2 UBQLN1 UBQLN4	3.38e-05	41	31	3	int:OR6T1
Interaction	C1QTNF4 interactions	UBQLN2 UBQLN1	3.42e-05	6	31	2	int:C1QTNF4
Interaction	NUP43 interactions	BCL9L SETD1A NCOA6 ZFHX3 SMARCAD1 PFDN5 LUC7L2	3.67e-05	625	31	7	int:NUP43
Interaction	CRX interactions	NCOA1 BCL9L ZFHX3 CHD7 ZFHX4	3.97e-05	254	31	5	int:CRX
Interaction	SMIM19 interactions	UBQLN2 UBQLN1	4.79e-05	7	31	2	int:SMIM19
Interaction	HERPUD1 interactions	UBQLN2 UBQLN1 UBQLN4	5.10e-05	47	31	3	int:HERPUD1
Interaction	EPS15L1 interactions	EPS15 UBQLN2 UBQLN1 LUC7L2	5.74e-05	138	31	4	int:EPS15L1
Interaction	GPR162 interactions	UBQLN2 UBQLN1	6.38e-05	8	31	2	int:GPR162
Interaction	WFDC12 interactions	UBQLN2 UBQLN1	6.38e-05	8	31	2	int:WFDC12
Interaction	IGFBP6 interactions	UBQLN2 UBQLN1 UBQLN4	6.53e-05	51	31	3	int:IGFBP6
Interaction	KDM1A interactions	EPS15 ZFHX3 SMARCAD1 PFDN5 CHD7 ZFHX4 LUC7L2 UBQLN4	6.62e-05	941	31	8	int:KDM1A
Interaction	STAM2 interactions	EPS15 UBQLN2 UBQLN1 UBQLN4	7.34e-05	147	31	4	int:STAM2
Interaction	CEBPA interactions	SUGP1 NCOA1 KIF4A NCOA6 PFDN5 CHD7 CLINT1 UBQLN1 SEPTIN2	7.43e-05	1245	31	9	int:CEBPA
Interaction	TLX3 interactions	BCL9L NCOA6 ZFHX3 CHD7 ZFHX4	7.57e-05	291	31	5	int:TLX3
Interaction	SERPINE1 interactions	UBQLN2 UBQLN1 UBQLN4	7.75e-05	54	31	3	int:SERPINE1
Interaction	SLC17A2 interactions	UBQLN2 SLC12A7 UBQLN4	8.64e-05	56	31	3	int:SLC17A2
Interaction	NPPA interactions	UBQLN2 UBQLN1 UBQLN4	1.01e-04	59	31	3	int:NPPA
Interaction	ZFAND2B interactions	UBQLN2 UBQLN1 UBQLN4	1.06e-04	60	31	3	int:ZFAND2B
Interaction	SEZ6L interactions	UBQLN2 UBQLN1	1.25e-04	11	31	2	int:SEZ6L
Interaction	RTL8A interactions	UBQLN2 UBQLN1	1.25e-04	11	31	2	int:RTL8A
Interaction	PAQR9 interactions	UBQLN2 UBQLN1	1.25e-04	11	31	2	int:PAQR9
Interaction	SLC45A4 interactions	UBQLN1 UBQLN4	1.25e-04	11	31	2	int:SLC45A4
Interaction	HERC3 interactions	NCOA1 UBQLN2 UBQLN1	1.29e-04	64	31	3	int:HERC3
Interaction	PHF5A interactions	SUGP1 SETD1A PFDN5 UBQLN2	1.32e-04	171	31	4	int:PHF5A
Interaction	DESI1 interactions	UBQLN2 UBQLN1 UBQLN4	1.35e-04	65	31	3	int:DESI1
Interaction	VSX1 interactions	ZFHX3 CHD7 ZFHX4	1.41e-04	66	31	3	int:VSX1
Interaction	MYDGF interactions	UBQLN2 UBQLN1 UBQLN4	1.41e-04	66	31	3	int:MYDGF
Interaction	TEAD1 interactions	NCOA1 ZFHX3 CHD7 ZFHX4	1.47e-04	176	31	4	int:TEAD1
Interaction	FDCSP interactions	SCAF11 UBQLN2	1.50e-04	12	31	2	int:FDCSP
Interaction	PSMD8 interactions	PFDN5 UBQLN2 UBQLN1 UBQLN4	1.67e-04	182	31	4	int:PSMD8
Interaction	PPIB interactions	GPC1 SUGP1 UBQLN2 UBQLN1 UBQLN4	1.68e-04	345	31	5	int:PPIB
Interaction	TERF2IP interactions	SUGP1 KIF4A SETD1A NCOA6 SCAF11 CHD7	1.69e-04	552	31	6	int:TERF2IP
Interaction	LHX2 interactions	BCL9L ZFHX3 CHD7 ZFHX4	1.71e-04	183	31	4	int:LHX2
Interaction	RTL8B interactions	UBQLN2 UBQLN1	1.77e-04	13	31	2	int:RTL8B
Interaction	PLAAT2 interactions	UBQLN2 UBQLN1	1.77e-04	13	31	2	int:PLAAT2
Interaction	SOD3 interactions	UBQLN2 UBQLN1	1.77e-04	13	31	2	int:SOD3
Interaction	DAZAP2 interactions	UBQLN2 UBQLN1 UBQLN4 SEPTIN2	1.82e-04	186	31	4	int:DAZAP2
Interaction	UBFD1 interactions	UBQLN2 UBQLN1 UBQLN4	1.83e-04	72	31	3	int:UBFD1
Interaction	YAP1 interactions	KIF4A BCL9L SETD1A NCOA6 CLINT1 UBQLN2 UBQLN1 SEPTIN2	1.90e-04	1095	31	8	int:YAP1
Interaction	SMAP2 interactions	PFDN5 CLINT1 UBQLN2 ARHGAP18	1.93e-04	189	31	4	int:SMAP2
Interaction	DOK4 interactions	SMARCAD1 PFDN5 ARHGAP18	1.98e-04	74	31	3	int:DOK4
Interaction	KIF4B interactions	KIF4A KIF4B	2.06e-04	14	31	2	int:KIF4B
Interaction	H2BC8 interactions	SUGP1 SEPTIN1 KIF4A SCAF11 SMARCAD1 CHD7	2.13e-04	576	31	6	int:H2BC8
Interaction	FOXL1 interactions	ZFHX3 SMARCAD1 CHD7 ZFHX4	2.22e-04	196	31	4	int:FOXL1
Interaction	FZD7 interactions	UBQLN2 UBQLN1 UBQLN4	2.23e-04	77	31	3	int:FZD7
Interaction	POU5F1 interactions	SUGP1 KIF4A ZFHX3 SCAF11 CHD7 SEPTIN2	2.29e-04	584	31	6	int:POU5F1
Interaction	GATA2 interactions	NCOA6 ZFHX3 CHD7 ZFHX4	2.36e-04	199	31	4	int:GATA2
Interaction	SOX7 interactions	NCOA1 CHD7 ZFHX4	2.69e-04	82	31	3	int:SOX7
Interaction	GUCA2A interactions	UBQLN2 UBQLN1	2.71e-04	16	31	2	int:GUCA2A
Interaction	FKBP2 interactions	UBQLN2 UBQLN1 UBQLN4	2.79e-04	83	31	3	int:FKBP2
Interaction	ACBD5 interactions	EPS15 UBQLN2 UBQLN1 UBQLN4	2.84e-04	209	31	4	int:ACBD5
Interaction	SCG2 interactions	UBQLN1 UBQLN4	3.07e-04	17	31	2	int:SCG2
Interaction	COL9A2 interactions	UBQLN2 UBQLN1	3.07e-04	17	31	2	int:COL9A2
Interaction	GSC interactions	BCL9L ZFHX3 ZFHX4	3.20e-04	87	31	3	int:GSC
Interaction	NPY interactions	UBQLN2 UBQLN1	3.45e-04	18	31	2	int:NPY
Interaction	DPRX interactions	ZFHX3 ZFHX4	3.45e-04	18	31	2	int:DPRX
Interaction	PRAP1 interactions	UBQLN2 UBQLN1	3.45e-04	18	31	2	int:PRAP1
Interaction	NBL1 interactions	UBQLN2 UBQLN1	3.45e-04	18	31	2	int:NBL1
Interaction	DUXB interactions	CHD7 ZFHX4	3.45e-04	18	31	2	int:DUXB
Interaction	CDIP1 interactions	UBQLN2 UBQLN1	3.45e-04	18	31	2	int:CDIP1
Interaction	H2BC3 interactions	KIF4A SETD1A CHD7 UBQLN1 UBQLN4	3.57e-04	406	31	5	int:H2BC3
Interaction	SNRNP40 interactions	SUGP1 BCL9L ZFHX3 SCAF11 SMARCAD1 PFDN5	3.65e-04	637	31	6	int:SNRNP40
Interaction	SPAG8 interactions	PFDN5 UBQLN1 UBQLN4	3.65e-04	91	31	3	int:SPAG8
Interaction	PRMT2 interactions	NCOA1 SETD1A NCOA6	3.65e-04	91	31	3	int:PRMT2
Interaction	RAD23A interactions	EPS15 UBQLN2 UBQLN1 UBQLN4	3.69e-04	224	31	4	int:RAD23A
Interaction	CSN3 interactions	UBQLN2 UBQLN1	3.85e-04	19	31	2	int:CSN3
Interaction	FLNA interactions	GPC1 EPS15 PFDN5 CLINT1 UBQLN1 LUC7L2	4.00e-04	648	31	6	int:FLNA
Interaction	IST1 interactions	UBQLN2 UBQLN1 ARHGAP18	4.02e-04	94	31	3	int:IST1
Interaction	MLLT6 interactions	EPS15 UBQLN1 UBQLN4	4.14e-04	95	31	3	int:MLLT6
Interaction	RAI2 interactions	UBQLN1 UBQLN4	4.28e-04	20	31	2	int:RAI2
Cytoband	12q12	SCAF11 PFDN5	4.68e-04	47	31	2	12q12
Cytoband	Ensembl 112 genes in cytogenetic band chr5q33	KIF4B CLINT1	2.90e-03	118	31	2	chr5q33
Cytoband	Ensembl 112 genes in cytogenetic band chr2p23	NCOA1 DTNB	4.57e-03	149	31	2	chr2p23
Cytoband	Ensembl 112 genes in cytogenetic band chr2q37	GPC1 SEPTIN2	1.02e-02	226	31	2	chr2q37
Cytoband	Ensembl 112 genes in cytogenetic band chr16p11	SEPTIN1 SETD1A	1.51e-02	278	31	2	chr16p11
GeneFamily	Ubiquilin family	UBQLN2 UBQLN1 UBQLN4	1.80e-08	5	23	3	783
GeneFamily	Septins	SEPTIN1 SEPTIN2	1.20e-04	13	23	2	732
GeneFamily	Zinc fingers C2H2-type\|ZF class homeoboxes and pseudogenes	ZFHX3 ZFHX4	1.61e-04	15	23	2	529
GeneFamily	Kinesins\|Pleckstrin homology domain containing	KIF4A KIF4B	1.55e-03	46	23	2	622
Coexpression	KRAS.AMP.LUNG_UP.V1_DN	SETD1A C5 RHOBTB1 DTNB	2.32e-05	142	31	4	M2859
Coexpression	GSE37605_NOD_VS_C57BL6_IRES_GFP_TREG_UP	NCOA1 CHD7 DTNB LUC7L2	3.61e-05	159	31	4	M8814
Coexpression	GSE20198_IL12_VS_IFNA_TREATED_ACT_CD4_TCELL_DN	NCOA1 SETD1A UBQLN2 UBQLN1	8.64e-05	199	31	4	M7374
Coexpression	GSE36888_UNTREATED_VS_IL2_TREATED_TCELL_17H_UP	PFDN5 C5 RHOBTB1 SEPTIN2	8.64e-05	199	31	4	M8734
Coexpression	GSE3994_WT_VS_PAC1_KO_ACTIVATED_MAST_CELL_DN	GPC1 SUGP1 CHD7 ARHGAP18	8.81e-05	200	31	4	M6372
Coexpression	GSE3982_DC_VS_TH1_UP	GPC1 C5 RUFY3 SEPTIN2	8.81e-05	200	31	4	M5481
Coexpression	GSE40274_FOXP3_VS_FOXP3_AND_LEF1_TRANSDUCED_ACTIVATED_CD4_TCELL_DN	SMARCAD1 ARHGAP18 RUFY3 UBQLN4	8.81e-05	200	31	4	M9188
Coexpression	TABULA_MURIS_SENIS_PANCREAS_PANCREATIC_BETA_CELL_AGEING	NCOA1 CHD7 RHOBTB1 LUC7L2	1.10e-04	212	31	4	MM3816
Coexpression	SHEN_SMARCA2_TARGETS_UP	NCOA1 NCOA6 CLINT1 UBQLN2 SEPTIN2	1.37e-04	429	31	5	M29
CoexpressionAtlas	DevelopingGonad_e11.5_ovary + mesonephros_emap-3226_top-relative-expression-ranked_1000	SETD1A ZFHX3 SCAF11 DEPDC1 SMARCAD1 CHD7 ZFHX4 LUC7L2 RUFY3	1.63e-06	815	31	9	gudmap_developingGonad_e11.5_ovary + mesonephros_1000
CoexpressionAtlas	DevelopingGonad_e11.5_ovary + mesonephros_emap-3226_top-relative-expression-ranked_500	SETD1A ZFHX3 CHD7 ZFHX4 LUC7L2 RUFY3	2.69e-05	417	31	6	gudmap_developingGonad_e11.5_ovary + mesonephros_500
CoexpressionAtlas	DevelopingGonad_e11.5_ovary + mesonephros_emap-3226_top-relative-expression-ranked_200	ZFHX3 ZFHX4 LUC7L2 RUFY3	8.54e-05	161	31	4	gudmap_developingGonad_e11.5_ovary + mesonephros_200
CoexpressionAtlas	DevelopingGonad_e12.5_ovary_emap-28876_top-relative-expression-ranked_1000	SETD1A EPS15 ZFHX3 SCAF11 ZFHX4 LUC7L2 RUFY3	1.29e-04	804	31	7	gudmap_developingGonad_e12.5_ovary_1000
CoexpressionAtlas	DevelopingGonad_e11.5_ovary + mesonephros_emap-3226_k-means-cluster#3_top-relative-expression-ranked_500	CHD7 ZFHX4 RUFY3	1.32e-04	68	31	3	gudmap_developingGonad_e11.5_ovary + mesonephros_k3_500
ToppCell	10x_3'_v2v3-Neoplastic-Differentiated-like-AC-like-AC-like_Prolif-C\|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	KIF4A DEPDC1 CLINT1 SEPTIN2	9.05e-06	191	31	4	588015d76b68488da6aa6603777682f3d81592bf
ToppCell	10x_3'_v2v3-Neoplastic-Stem-like-OPC-like-OPC-like_Prolif-C\|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	KIF4A DEPDC1 CLINT1 SEPTIN2	9.63e-06	194	31	4	ded64ddab86de17fcf8b70d31bc26796eb71d60f
ToppCell	Non-neuronal-Dividing-IPC\|World / Primary Cells by Cluster	KIF4A DEPDC1 CHD7 ZFHX4	1.09e-05	200	31	4	971533181daa1bfac1f1b8c507d2013f891f9078
ToppCell	Thalamus\|World / BrainAtlas - Mouse McCarroll V32	ZFHX3 SCAF11 ZFHX4	7.12e-05	116	31	3	5ddfb2dd5459ff6d7ae38163a38eae64fda283b7
ToppCell	Dividing_Macrophages-Donor_02\|World / lung cells shred on cell class, cell subclass, sample id	KIF4A KIF4B DEPDC1	1.47e-04	148	31	3	66b51aa6690bf8fbc90fa5a6f86191703e2d5046
ToppCell	E18.5-samps-Mesenchymal-Matrix_fibroblast-FB-1\|E18.5-samps / Age Group, Lineage, Cell class and subclass	GPC1 BCL9L NCOA6	1.81e-04	159	31	3	b4bc888e978b1b577721b891b0af6ba9a1607044
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell_cycling\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	KIF4A KIF4B DEPDC1	1.95e-04	163	31	3	3f434015c0cbefb31eeda133c34f75384c5f7e22
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell_cycling-Cycling_Proximal_Tubule_Epithelial_Cell_G2M\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	KIF4A KIF4B DEPDC1	2.02e-04	165	31	3	eec2d327c94832d1390314c93ef6a2be4648478b
ToppCell	renal_papilla_nuclei-Adult_normal_reference-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell_cycling-Cycling_Proximal_Tubule_Epithelial_Cell_G2M\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	KIF4A KIF4B DEPDC1	2.05e-04	166	31	3	2642544070564debe2deb2938d2c33997bf5ef02
ToppCell	3'-Airway_Nasal-Epithelial-Airway_epithelium-respiratory_basal_cell-Suprabasal-\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	CLINT1 ZFHX4 PLGRKT	2.05e-04	166	31	3	9fd9de82f98b9acdaa59ac98fb9664161514aec0
ToppCell	facs-GAT-Fat-3m-Lymphocytic-CD8-positive,_alpha-beta_T_cell\|GAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SEPTIN1 CHD7 SLC12A7	2.05e-04	166	31	3	3695407e4638f3c18fbff63daba52baa9256c429
ToppCell	renal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell_cycling\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	KIF4A KIF4B DEPDC1	2.09e-04	167	31	3	50c29ea660bf07b890e4ac1a1985d0761d863dee
ToppCell	renal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell_cycling-Cycling_Proximal_Tubule_Epithelial_Cell_G2M\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	KIF4A KIF4B DEPDC1	2.13e-04	168	31	3	d35944fd9fea9934ce1e76b2b35d48e2300cca61
ToppCell	droplet-Lung-30m-Hematologic-Lymphocytic_NK_ILC-natural_killer_cell-proliferating_NK\|30m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	GPC1 SEPTIN1 KIF4A	2.17e-04	169	31	3	822e5b6c1e55e196e6d2a38bf183fd220c45703e
ToppCell	PND03-Immune-Immune_Myeloid-Monocytic-Macrophage-iMON-iMON_G2M\|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	KIF4A DEPDC1 CLINT1	2.17e-04	169	31	3	4db49b7eaea34e6558ee73b01e76315e99cc880b
ToppCell	facs-Marrow-T-cells-3m-Myeloid-granulocytopoietic_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GPC1 DEPDC1 DTNB	2.24e-04	171	31	3	913bae728b5e653771a27c79a309eb023699f1d0
ToppCell	facs-Marrow-T-cells-3m-Myeloid-granulocytopoietic_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GPC1 DEPDC1 DTNB	2.24e-04	171	31	3	f28b2336057e353b96a6ff4581ec9fd0ca0789d9
ToppCell	droplet-Lung-nan-21m-Myeloid-Myeloid_Dendritic_Type_2\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CLINT1 RHOBTB1 ARHGAP18	2.36e-04	174	31	3	2afa5eea54b67c549c5058ece98296eee3829c11
ToppCell	PBMC_fresh-frozen-Severe-critical_convalescent_d42-56-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD4_c14-MKI67-CCL5_h\|Severe-critical_convalescent_d42-56 / Compartment, severity and other cell annotations on 10x 3' data (130k)	GPC1 KIF4A DEPDC1	2.61e-04	180	31	3	42f48e646fc6e72ad3cce72409ace3a0b64020a2
ToppCell	droplet-Thymus-nan-24m-Lymphocytic-DN_to_DP_transition,_dividing_(some_are_Cd8+/_Cd4+,_some_undergoing_VDJ_recombination)\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	KIF4A DEPDC1 ARHGAP18	2.65e-04	181	31	3	3fe648db1cb8326066d8bde3ca1287c5c9af19bd
ToppCell	facs-Marrow-Granulocytes-3m-Myeloid-granulocytopoietic_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GPC1 KIF4A DEPDC1	2.65e-04	181	31	3	566249e04dd491e6287ad2101b7b1ab11031ed8b
ToppCell	facs-Marrow-Granulocytes-3m-Myeloid-granulocytopoietic_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GPC1 KIF4A DEPDC1	2.65e-04	181	31	3	db9528dc7cb0230e4c36cb27da69102c588c7ee9
ToppCell	facs-Marrow-B-cells-18m-Myeloid-granulocytopoietic_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GPC1 KIF4A DEPDC1	2.69e-04	182	31	3	c075756cd4bb484ede1be2bcdb9eac60eab0573a
ToppCell	10x5'-Liver-Lymphocytic_T_CD4/8-lo-Cycling_T\|Liver / Manually curated celltypes from each tissue	KIF4A KIF4B DEPDC1	2.69e-04	182	31	3	81557cdc88777f3bd4e1dd18a760b08fc29122ef
ToppCell	facs-Marrow-B-cells-18m-Myeloid-granulocytopoietic_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GPC1 KIF4A DEPDC1	2.69e-04	182	31	3	9025178ede571e3808d4657ad4892152f336c9b4
ToppCell	URO-Lymphocyte-T_NK-T_NK_proliferative\|URO / Disease, Lineage and Cell Type	KIF4A KIF4B DEPDC1	2.82e-04	185	31	3	0ae9c646679c69a553eda670aef0e0495feb0286
ToppCell	PBMC_fresh-frozen-Severe-critical_progression_d03-09-Hematopoietic-Megakaryocytic\|Severe-critical_progression_d03-09 / Compartment, severity and other cell annotations on 10x 3' data (130k)	KIF4A DEPDC1 RHOBTB1	2.92e-04	187	31	3	69068480f6819a6c8560ecbb05deb156b4055e12
ToppCell	PBMC_fresh-frozen-Severe-critical_progression_d03-09-Hematopoietic-Megakaryocytic-Megakaryocyte-Mega\|Severe-critical_progression_d03-09 / Compartment, severity and other cell annotations on 10x 3' data (130k)	KIF4A DEPDC1 RHOBTB1	2.92e-04	187	31	3	9c8b932a15b8b50982cba4cf8db750e257eb9503
ToppCell	PBMC_fresh-frozen-Severe-critical_progression_d03-09-Hematopoietic\|Severe-critical_progression_d03-09 / Compartment, severity and other cell annotations on 10x 3' data (130k)	KIF4A DEPDC1 RHOBTB1	2.92e-04	187	31	3	46e15419e80bd7180f3171a99d845b01bb635e53
ToppCell	PBMC_fresh-frozen-Severe-critical_progression_d03-09-Hematopoietic-Megakaryocytic-Megakaryocyte\|Severe-critical_progression_d03-09 / Compartment, severity and other cell annotations on 10x 3' data (130k)	KIF4A DEPDC1 RHOBTB1	2.92e-04	187	31	3	0d17b07770e4c881a7ca53a5bd42471457d198fb
ToppCell	5'-Airway_Nasal-Epithelial-Epithelial_transtional-secretory-club_cell-Club_(non-nasal)-Club_(non-nasal)_L.0.4.0.1\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	NCOA1 CHD7 C5	2.92e-04	187	31	3	f5a202d5f8eb57b57d80815ce98774e04c387383
ToppCell	Smart-start-Cell-Wel_seq-Neoplastic-Stem-like-OPC-like-OPC-like_Prolif-E\|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	KIF4B DEPDC1 C5	2.96e-04	188	31	3	0476d7ee3e0ce78c3c5b111e9ade01098f9ea7ec
ToppCell	Multiple_Sclerosis-Lymphocyte-T_NK-T_NK_proliferative\|Multiple_Sclerosis / Disease, Lineage and Cell Type	KIF4A KIF4B DEPDC1	2.96e-04	188	31	3	6c05797a5d0635d89ffcf4aca52178687129ccb4
ToppCell	Somatosensory_Cortex_(S1)-Non-neuronal\|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	ZFHX3 CHD7 ZFHX4	3.01e-04	189	31	3	42ab4cc5fbf8580841f31889446fe4499df1a464
ToppCell	Int-URO-Lymphocyte-T_NK-T_NK_proliferative\|Int-URO / Disease, Lineage and Cell Type	KIF4A KIF4B DEPDC1	3.05e-04	190	31	3	005967c540418b85311308072a07c684f4296aef
ToppCell	normal_Pleural_Fluid-T/NK_cells-Undetermined\|normal_Pleural_Fluid / Location, Cell class and cell subclass	KIF4A KIF4B DEPDC1	3.05e-04	190	31	3	165c61443ff0c8efbdad3b052bb00f46d81c5203
ToppCell	droplet-Marrow-BM_(NON-STC)-30m-Myeloid-granulocytopoietic_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	KIF4A DEPDC1 LUC7L2	3.05e-04	190	31	3	4288189e3a499c395896c950598810b02f401685
ToppCell	10x_3'_v2v3-Non-neoplastic-Lymphoid-CD4/CD8-CD4_rest-C\|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	CLINT1 C5 SEPTIN2	3.05e-04	190	31	3	69c5c4d5f4fb6e5ae2c9dbf9d209faf093c3f769
ToppCell	droplet-Large_Intestine-COLON_PROXIMAL\|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SCAF11 SMARCAD1 CLINT1	3.10e-04	191	31	3	60c986d2dcbc19d9338c03da6cb5e1d92fd48f8e
ToppCell	droplet-Lung-LUNG-30m-Lymphocytic-Proliferating_T\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SEPTIN1 KIF4A DEPDC1	3.10e-04	191	31	3	239300ff76f2c855b2b04d3002461158be90a01b
ToppCell	E17.5-Endothelial-proliferative_endothelial_cell-proliferative_endothelial_cell\|E17.5 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	KIF4A DEPDC1 ARHGAP18	3.10e-04	191	31	3	efe0cb0b6602621f5eda72a723b83b38bf15607f
ToppCell	E17.5-Endothelial-proliferative_endothelial_cell\|E17.5 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	KIF4A DEPDC1 ARHGAP18	3.10e-04	191	31	3	00676c598f6dae0ff9158d064248f1265432f3e1
ToppCell	(3)_Macrophage_Dividing\|World / Lung cell shreds - cell class (v4) and cell subclass (v4)	KIF4A KIF4B DEPDC1	3.10e-04	191	31	3	b42f0b89bb94fd43786ff50f1caeb3ebfbbb43fd
ToppCell	droplet-Large_Intestine-COLON_PROXIMAL-30m\|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SCAF11 SMARCAD1 CLINT1	3.10e-04	191	31	3	973117730d6ba5f127e7a0bfabfd0ff2ca7ac131
ToppCell	367C-Myeloid-Macrophage-FABP4+_Macrophage_proliferating\|367C / Donor, Lineage, Cell class and subclass (all cells)	KIF4A KIF4B DEPDC1	3.25e-04	194	31	3	a12b64945e10f00aa983678a02586c59badc1570
ToppCell	severe-Lymphocytic-CD4_T_cells_2\|severe / Cohort 2 (Rhapsody WB + PBMC) with disease condition, lineage and cell classs	SEPTIN1 BCL9L PFDN5	3.34e-04	196	31	3	1b06639b7d2b81a1e5bcc455f3adda039f42ba57
ToppCell	367C-Myeloid-Macrophage-FABP4+_Macrophage_proliferating\|Myeloid / Donor, Lineage, Cell class and subclass (all cells)	KIF4A KIF4B DEPDC1	3.34e-04	196	31	3	9591a6a3477ed6a1e2e016f7542e38603d8b16cb
ToppCell	5'-Parenchyma_lung-Immune_Lymphocytic-Lymphocytic_T/NK-T_cell-T_cells_proliferating-T_cells_proliferating_L.1.1.3.1\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	SEPTIN1 KIF4A DEPDC1	3.34e-04	196	31	3	9d4f0a95e49bda25864cbe27e4e86096cba5609f
ToppCell	(3)_MNP-(3)_Macrophage_Dividing\|(3)_MNP / Lung cell shreds - cell class (v4) and cell subclass (v4)	KIF4A KIF4B DEPDC1	3.40e-04	197	31	3	048bc4f8fd5d4f394e2384700640f72042336597
ToppCell	3'-Broncho-tracheal-Epithelial-Airway_epithelium-respiratory_basal_cell-Suprabasal-Suprabasal_L.0.0.1.1\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	GPC1 KIF4A DEPDC1	3.40e-04	197	31	3	1d4ccca2ff46fccb3ac052b5148cb7f94231d65a
ToppCell	distal-Hematologic-Proliferating_NK/T-2\|distal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	KIF4A KIF4B DEPDC1	3.40e-04	197	31	3	04b10879e48c101d1de449db0bc6b6484090b965
ToppCell	PCW_10-12-Endothelial-Endothelial_cycling-endo_proliferating2_(14)\|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung	KIF4A DEPDC1 ARHGAP18	3.40e-04	197	31	3	491e12a5fca06b86443c0173f5fa750ea3b8a715
ToppCell	PCW_13-14-Endothelial-Endothelial_cycling-endo_proliferating2_(14)\|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung	KIF4A DEPDC1 ARHGAP18	3.40e-04	197	31	3	8e655db7c6f04d49927a1f0a75178e5955b4af08
ToppCell	10x_3'_v2v3-Neoplastic-Differentiated-like-AC-like-AC-like_Prolif-B\|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	GPC1 KIF4A DEPDC1	3.45e-04	198	31	3	1fa213e79d828bff6465bde116536dd1b80d94e0
ToppCell	cycling_basal_cell\|World / shred by cell class for bronchial biopsy	KIF4A KIF4B DEPDC1	3.45e-04	198	31	3	d5306121a75c5eb37d62c353799a98e6ba5ab63f
ToppCell	Healthy_Control-Lymphoid\|Healthy_Control / Condition, Lineage, Cell class and cell subclass	SEPTIN1 KIF4A DEPDC1	3.45e-04	198	31	3	c176c583f426e4373daca4a696ab8832e838cfbf
ToppCell	distal-1-Hematologic-Proliferating_Macrophage\|1 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	KIF4A KIF4B DEPDC1	3.45e-04	198	31	3	df3f5559ecd1f3cd1fd60e39dbad8741309e83a3
ToppCell	Biopsy_Other_PF-Immune-Proliferating_T_cells\|Biopsy_Other_PF / Sample group, Lineage and Cell type	SEPTIN1 KIF4A DEPDC1	3.50e-04	199	31	3	1d55d06e658939b78ea046553757821381eaa026
ToppCell	COVID-19-Lymphoid-Proliferating_CD4_T_cells\|COVID-19 / Condition, Lineage and Cell class	SEPTIN1 KIF4A DEPDC1	3.50e-04	199	31	3	e1dfc856a85a91e8f7ab8d600a8a891d16b2aefb
ToppCell	10x_3'_v2v3-Neoplastic-Stem-like-NPC-like-NPC-like_Prolif-G\|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	KIF4A DEPDC1 CHD7	3.50e-04	199	31	3	53b3d35767889a152f1f38e8f6f0ba8f7a7690f2
ToppCell	Healthy_Control-Lymphoid-T\|Healthy_Control / Condition, Lineage, Cell class and cell subclass	SEPTIN1 KIF4A DEPDC1	3.50e-04	199	31	3	f22438fc9c02d0a4d7c936f9420b913aca851ea1
ToppCell	control-HLA-DR+_CD83+_Monocyte\|control / Cohort 1 (10x PBMC) with disease condition, cell group and cell class	NCOA1 ZFHX3 RUFY3	3.50e-04	199	31	3	f1b370d2869ad29c9d8ff41fdcc486fffa781ee2
ToppCell	Non-neuronal-Dividing-IPC-IPC-div2\|World / Primary Cells by Cluster	KIF4A CHD7 ZFHX4	3.55e-04	200	31	3	4923d7a4f00853c4d76fc1cc0fa82d522a2302e7
ToppCell	healthy_donor-Lymphocytic-Proliferative_Lymphocyte-\|healthy_donor / Disease condition, Lineage, Cell class and subclass	KIF4A KIF4B DEPDC1	3.55e-04	200	31	3	415e7556b5ac45688e2c6c30a52bd40e0eb27c7d
ToppCell	BAL-Severe-Lymphocyte-T/NK-Other_T-T/NK_proliferative\|Severe / Location, Disease Group, Cell group, Cell class (2021.03.09)	SEPTIN1 KIF4A DEPDC1	3.55e-04	200	31	3	60d11275f06490f86f400a2802492f9c1b570400
ToppCell	Severe-Lymphoid-T-Proliferating_T\|Severe / Condition, Lineage, Cell class and cell subclass	SEPTIN1 KIF4A DEPDC1	3.55e-04	200	31	3	266270c756fb69945449ce02da04743cd31f8158
ToppCell	Fetal_brain-organoid_Tanaka_cellReport-GW10-Stem_cells\|GW10 / Sample Type, Dataset, Time_group, and Cell type.	KIF4A DEPDC1 ZFHX4	3.55e-04	200	31	3	4c22a1f35ff496fa6af2ab171f2936785272bc06
ToppCell	BAL-Severe-Lymphocyte-T/NK-Other_T\|Severe / Location, Disease Group, Cell group, Cell class (2021.03.09)	SEPTIN1 KIF4A DEPDC1	3.55e-04	200	31	3	535f6fba8d03873ba35c9949579161dc41cd7a60
ToppCell	Fetal_brain-fetalBrain_Zhong_nature-GW16-Stem_cells\|GW16 / Sample Type, Dataset, Time_group, and Cell type.	KIF4A DEPDC1 ZFHX4	3.55e-04	200	31	3	b71138729d2a81cc2f30e3bc15853516a525a17f
ToppCell	Severe_COVID-19-T/NK-proliferating_T/NK\|Severe_COVID-19 / Disease group,lineage and cell class （2021.01.30）	SEPTIN1 KIF4A DEPDC1	3.55e-04	200	31	3	52265e761a961f3724b388285e0919bd58847138
ToppCell	Fetal_brain-fetalBrain_Zhong_nature-GW26-OPC_related-OPC\|GW26 / Sample Type, Dataset, Time_group, and Cell type.	KIF4A DEPDC1 CHD7	3.55e-04	200	31	3	02594c1edbc9f2cf831639cd83363abd2551cb94
ToppCell	LPS_IL1RA-Endothelial-Endothelial-Alv_Gen_Intermediate\|LPS_IL1RA / Treatment groups by lineage, cell group, cell type	RHOBTB1 ARHGAP18 SEPTIN2	3.55e-04	200	31	3	b70b7adb7c187e6253c7f0bb4c1f09c85ef7142c
ToppCell	BAL-Severe-Lymphocyte-T/NK-Other_T-T/NK_proliferative\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	SEPTIN1 KIF4A DEPDC1	3.55e-04	200	31	3	dd7ad295ab3ba4c19babffb1625900db414bb5a9
ToppCell	Non-neuronal-Dividing-IPC-IPC-div2-5\|World / Primary Cells by Cluster	KIF4A CHD7 ZFHX4	3.55e-04	200	31	3	dc1c1506823eaa105f1532c6b5d4efa14e788314
ToppCell	Caecum-(5)_Dendritic_cell-(52)_cycling_DCs\|Caecum / shred on region, Cell_type, and subtype	KIF4A DEPDC1 RHOBTB1	3.55e-04	200	31	3	3b04d08e9122c23f42f66bc74c06cf24e1693987
ToppCell	Caecum-Dendritic_cell-cycling_DCs\|Caecum / Region, Cell class and subclass	KIF4A DEPDC1 RHOBTB1	3.55e-04	200	31	3	608be9bfe74f8d3202aa92b2905452a06f340f76
ToppCell	Biopsy_IPF-Immune-Proliferating_T_cells\|Biopsy_IPF / Sample group, Lineage and Cell type	SEPTIN1 KIF4A DEPDC1	3.55e-04	200	31	3	c43d1a83b2a8ad060f3d80c9438da8b7a5e307fb
ToppCell	healthy_donor-Lymphocytic-Proliferative_Lymphocyte\|healthy_donor / Disease condition, Lineage, Cell class and subclass	KIF4A KIF4B DEPDC1	3.55e-04	200	31	3	e4eb915c29909cf8535a3603c68976545c05e54b
ToppCell	mLN-Macrophage-LYVE1_Macrophage\|Macrophage / Region, Cell class and subclass	SCAF11 CLINT1 ARHGAP18	3.55e-04	200	31	3	e3c15e0e1c2602b0cc9ab8cc50c978d265350c94
ToppCell	Biopsy_Control_(H.)-Immune-Proliferating_T_cells\|Biopsy_Control_(H.) / Sample group, Lineage and Cell type	SEPTIN1 KIF4A DEPDC1	3.55e-04	200	31	3	dd374e153106fff8a22483ba7f63b3fa3d3ab2ea
ToppCell	BAL-Severe-Lymphocyte-T/NK-Other_T-T/NK_proliferative-\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)	SEPTIN1 KIF4A DEPDC1	3.55e-04	200	31	3	0e44a55d65b72eb40543d3bde301f8598ac251c3
ToppCell	5'-Parenchyma_lung-Immune_Lymphocytic-Lymphocytic_T/NK-T_cell\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	SEPTIN1 KIF4A DEPDC1	3.55e-04	200	31	3	6145bdee0d9954da7b096be4fe797066a6df2bd0
ToppCell	Fetal_brain-fetalBrain_Zhong_nature-GW26-OPC_related\|GW26 / Sample Type, Dataset, Time_group, and Cell type.	KIF4A DEPDC1 CHD7	3.55e-04	200	31	3	46521d83b917b0357601db8783c8da6b73730d60
ToppCell	Fetal_brain-fetalBrain_Zhong_nature-GW16-Stem_cells-Stem_cells\|GW16 / Sample Type, Dataset, Time_group, and Cell type.	KIF4A DEPDC1 ZFHX4	3.55e-04	200	31	3	8f3067b52865a0f5488e4df0d5a4fea80135cef5
ToppCell	BAL-Severe-Lymphocyte-T/NK-Other_T-T/NK_proliferative-\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	SEPTIN1 KIF4A DEPDC1	3.55e-04	200	31	3	3c3ac587ad98e3f6be809eac18c7742a23140de1
ToppCell	Brain_organoid-organoid_Tanaka_cellReport-5w-Neuronal-Intermediate\|5w / Sample Type, Dataset, Time_group, and Cell type.	SETD1A ZFHX3 ZFHX4	3.55e-04	200	31	3	c92e4fc0442404481fcac623d691dae6215b852d
ToppCell	Fetal_brain-organoid_Tanaka_cellReport-GW10-Stem_cells-Neuroepithelial_cell\|GW10 / Sample Type, Dataset, Time_group, and Cell type.	KIF4A DEPDC1 ZFHX4	3.55e-04	200	31	3	0632b8d3a1be437f146bc86aae9646303e37a0bd
ToppCell	BAL-Severe-Lymphocyte-T/NK-Other_T\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	SEPTIN1 KIF4A DEPDC1	3.55e-04	200	31	3	5c84aaedac9f27da0da0493dab7c8f7a4d66888c
ToppCell	5'-Parenchyma_lung-Immune_Lymphocytic-Lymphocytic_T/NK-T_cell-T_cells_proliferating\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	SEPTIN1 KIF4A DEPDC1	3.55e-04	200	31	3	f95769e24763900eac317c6f8adbf064bae9feaf
Drug	2f34	EPS15 CLINT1 UBQLN2 UBQLN1 UBQLN4	5.19e-06	188	31	5	CID006420160
Drug	Trimethoprim [738-70-5]; Down 200; 13.8uM; MCF7; HT_HG-U133A	GPC1 SUGP1 NCOA1 ZFHX3 RUFY3	7.02e-06	200	31	5	4701_DN
Drug	Ivermectin [70288-86-7]; Down 200; 4.6uM; PC3; HT_HG-U133A	SUGP1 NCOA1 ZFHX3 CHD7 C5	7.02e-06	200	31	5	5853_DN
Drug	chloroacetyl-CoA	PFDN5 DTNB	1.07e-05	4	31	2	CID003081467
Drug	androstan-3-ol	NCOA1 NCOA6	2.68e-05	6	31	2	ctd:C000658
Drug	retinyl stearate	NCOA6 PFDN5	3.75e-05	7	31	2	CID006438398
Drug	Trichostatin A, from Streptomyces sp.; Down 200; 0.1uM; MCF7; HT_HG-U133A	SUGP1 ZFHX3 LUC7L2 RUFY3	6.53e-05	161	31	4	4768_DN
Drug	Trichostatin A, Streptomyces sp.; Down 200; 0.1uM; MCF7; HT_HG-U133A	NCOA6 SCAF11 RHOBTB1 LUC7L2	9.43e-05	177	31	4	6972_DN
Drug	Ethaverine hydrochloride [985-13-7]; Up 200; 9.2uM; HL60; HT_HG-U133A	GPC1 ZFHX3 SLC12A7 RUFY3	1.17e-04	187	31	4	3037_UP
Drug	Pyrvinium pamoate [3546-41-6]; Down 200; 3.4uM; PC3; HT_HG-U133A	SUGP1 NCOA1 ZFHX3 C5	1.37e-04	195	31	4	6339_DN
Drug	Clebopride maleate [84370-95-6]; Up 200; 8.2uM; HL60; HT_HG-U133A	SUGP1 SETD1A DTNB RUFY3	1.37e-04	195	31	4	1292_UP
Drug	arteether	PFDN5 CLINT1	1.39e-04	13	31	2	CID000072416
Drug	Mifepristone [84371-65-3]; Down 200; 9.4uM; PC3; HT_HG-U133A	SUGP1 CLINT1 ZFHX4 RUFY3	1.40e-04	196	31	4	5827_DN
Drug	Xamoterol hemifumarate [73210-73-8]; Up 200; 5uM; HL60; HT_HG-U133A	GPC1 ZFHX3 ZFHX4 RUFY3	1.40e-04	196	31	4	3064_UP
Drug	Muramic acid, N-acetyl [10597-89-4]; Up 200; 13.6uM; HL60; HT_HG-U133A	GPC1 NCOA1 SETD1A C5	1.40e-04	196	31	4	1326_UP
Drug	AH23848 hemicalcium salt hydrate; Up 200; 1uM; MCF7; HT_HG-U133A	GPC1 SUGP1 DTNB RUFY3	1.42e-04	197	31	4	6890_UP
Drug	Carbinoxamine maleate salt [3505-38-2]; Down 200; 9.8uM; PC3; HT_HG-U133A	SUGP1 NCOA1 RHOBTB1 RUFY3	1.42e-04	197	31	4	7138_DN
Drug	Gliquidone [33342-05-1]; Down 200; 7.6uM; HL60; HT_HG-U133A	SUGP1 SETD1A RHOBTB1 RUFY3	1.42e-04	197	31	4	3126_DN
Drug	Florfenicol [73231-34-2]; Down 200; 11.2uM; MCF7; HT_HG-U133A	SUGP1 NCOA1 ZFHX3 RUFY3	1.42e-04	197	31	4	5300_DN
Drug	genistein; Down 200; 10uM; MCF7; HT_HG-U133A_EA	NCOA1 SCAF11 C5 SLC12A7	1.45e-04	198	31	4	1073_DN
Drug	Oxprenolol hydrochloride [6452-73-9]; Down 200; 13.2uM; PC3; HT_HG-U133A	SUGP1 NCOA1 RHOBTB1 RUFY3	1.45e-04	198	31	4	5871_DN
Drug	Equilin [474-86-2]; Down 200; 15uM; PC3; HT_HG-U133A	SUGP1 ZFHX3 CHD7 SLC12A7	1.45e-04	198	31	4	4659_DN
Drug	Ribavirin [36791-04-5]; Down 200; 16.4uM; HL60; HT_HG-U133A	SUGP1 NCOA1 ZFHX4 RUFY3	1.45e-04	198	31	4	3142_DN
Drug	Flumethasone [2135-17-3]; Down 200; 9.8uM; MCF7; HT_HG-U133A	SUGP1 NCOA1 ZFHX3 RUFY3	1.48e-04	199	31	4	3410_DN
Drug	Spironolactone [52-01-7]; Down 200; 9.6uM; PC3; HT_HG-U133A	ZFHX3 CHD7 C5 RUFY3	1.48e-04	199	31	4	5781_DN
Drug	Bupropion hydrochloride [31677-93-7]; Down 200; 14.4uM; PC3; HT_HG-U133A	SUGP1 NCOA1 ZFHX3 SLC12A7	1.51e-04	200	31	4	5782_DN
Drug	K2PtCl4	PFDN5 DTNB	1.62e-04	14	31	2	CID003013632
Disease	amyotrophic lateral sclerosis type 15 (implicated_via_orthology)	UBQLN2 UBQLN1 UBQLN4	9.48e-10	3	30	3	DOID:0060206 (implicated_via_orthology)
Disease	frontotemporal dementia (implicated_via_orthology)	UBQLN2 UBQLN1 UBQLN4	2.07e-07	12	30	3	DOID:9255 (implicated_via_orthology)
Disease	amyotrophic lateral sclerosis (implicated_via_orthology)	UBQLN2 UBQLN1 UBQLN4	3.78e-06	30	30	3	DOID:332 (implicated_via_orthology)
Disease	phosphatidylcholine measurement	SUGP1 NCOA1 ZFHX3 CHD7	1.89e-04	284	30	4	EFO_0010226
Disease	testosterone measurement	NCOA1 NCOA6 ZFHX3 CHD7 UBQLN2 ZFHX4 UBQLN4	2.35e-04	1275	30	7	EFO_0004908
Disease	Immunologic Deficiency Syndromes	CHD7 C5	2.49e-04	23	30	2	C0021051
Disease	low density lipoprotein cholesterol measurement, response to escitalopram, response to citalopram	ZFHX3 PLGRKT	2.72e-04	24	30	2	EFO_0004611, EFO_0006329, EFO_0007871
Disease	neurodegenerative disease (implicated_via_orthology)	UBQLN2 UBQLN1 UBQLN4	4.28e-04	145	30	3	DOID:1289 (implicated_via_orthology)
Disease	epilepsy (implicated_via_orthology)	KIF4A KIF4B SLC12A7	6.02e-04	163	30	3	DOID:1826 (implicated_via_orthology)
Disease	lung adenocarcinoma	NCOA1 SLC12A7 DTNB	7.28e-04	174	30	3	EFO_0000571
Disease	obesity (implicated_via_orthology)	NCOA1 ZFHX3 ZFHX4	1.34e-03	215	30	3	DOID:9970 (implicated_via_orthology)
Disease	neutrophil count, basophil count	NCOA1 CHD7 SLC12A7	1.51e-03	224	30	3	EFO_0004833, EFO_0005090
Disease	breast carcinoma (is_marker_for)	NCOA1 ZFHX3	2.06e-03	66	30	2	DOID:3459 (is_marker_for)
Disease	total cholesterol measurement, hematocrit, stroke, ventricular rate measurement, body mass index, atrial fibrillation, high density lipoprotein cholesterol measurement, coronary artery disease, diastolic blood pressure, triglyceride measurement, systolic blood pressure, heart failure, diabetes mellitus, glucose measurement, mortality, cancer	SUGP1 ZFHX3	2.25e-03	69	30	2	EFO_0000275, EFO_0000400, EFO_0000712, EFO_0001645, EFO_0003144, EFO_0004340, EFO_0004348, EFO_0004352, EFO_0004468, EFO_0004530, EFO_0004574, EFO_0004612, EFO_0006335, EFO_0006336, EFO_0007928, MONDO_0004992
Disease	Prostatic Neoplasms	NCOA1 ZFHX3 SMARCAD1 CHD7	3.35e-03	616	30	4	C0033578
Disease	Malignant neoplasm of prostate	NCOA1 ZFHX3 SMARCAD1 CHD7	3.35e-03	616	30	4	C0376358
Disease	reaction time measurement	GPC1 NCOA1 ZFHX3 TOPAZ1	4.24e-03	658	30	4	EFO_0008393
Disease	glycoprotein measurement	SUGP1 ZFHX3	6.52e-03	119	30	2	EFO_0004555
Disease	C-reactive protein measurement	NCOA6 SCAF11 CHD7 DTNB SEPTIN2	6.88e-03	1206	30	5	EFO_0004458

Protein segments in the cluster

Peptide	Gene	Start	Entry
EQQKMHLMDQPNRMM	CHD7	76	Q9P2D1
MIQQQNMQQPMNVMT	CLINT1	506	Q14677
MTIRQQIMQLKIMTN	GPC1	451	P35052
AMKQAVMEMMSQKIQ	PFDN5	126	Q99471
QLIMQSEMRERQMAM	PLGRKT	31	Q9HBL7
MRMISRMSQNVDMPK	DEPDC1	621	Q5TB30
QQQQQQQMMMMLMMQ	NCOA6	1026	Q14686
EMMQTAMQNTMLING	C5	281	P01031
NMNMNVNMNMNMNLN	BCL9L	771	Q86UU0
VNMNMNMNLNVQMTP	BCL9L	776	Q86UU0
VQMTPQQQMLMSQKM	BCL9L	786	Q86UU0
QRKIMLNMFLDTMMA	DTNB	201	O60941
RMMKNQRVQLMRQMK	KIF4A	641	O95239
WMMKNQRVQLMRQMK	KIF4B	641	Q2VIQ3
QQEISSMQMKLMEMK	EPS15	486	P42566
TLMMEQRSQMLKQMQ	SLC12A7	926	Q9Y666
NMMQPQMNVMQQQMN	SCAF11	1206	Q99590
MSAQAQMRAMLDQLM	LUC7L2	1	Q9Y383
QISMRQEMELAMKML	RUFY3	366	Q7L099
MCNVMMQLRKMANHP	SMARCAD1	771	Q9H4L7
TNVQNMNPMMAQMQM	NCOA1	1326	Q15788
RMMVENIMNKEAFMN	RHOBTB1	446	O94844
MPMSFQMQTQMLTRL	SETD1A	676	O15047
RRMQEMLEKMQAQMQ	SEPTIN1	346	Q8WYJ6
DMIMQHKRAMQDMQL	SUGP1	456	Q8IWZ8
HMHNMMLLQQNMKQI	ZFHX4	791	Q86UP3
AMMQEMMRNQDRALS	UBQLN1	246	Q9UMX0
NKMTVMNVAMVMAPN	ARHGAP18	471	Q8N392
VRQNRSKENVSMMML	TOPAZ1	726	Q8N9V7
RMQEMIARMQAQMQM	SEPTIN2	331	Q15019
MQQQLMASPEMMIQI	UBQLN2	171	Q9UHD9
RHMIMANPQMQQLME	UBQLN4	216	Q9NRR5
AMMQEMMRNQDRALS	UBQLN4	256	Q9NRR5
EKHMHNMMLLQQNMT	ZFHX3	826	Q15911