Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctioninorganic anion transmembrane transporter activity

GABRB2 SLC6A18 GABRB3 ABCC1 BEST3 ABCC5 ABCC9 ANO5 SLC26A1 SLC6A3 SLC6A11 CLCN5

2.32e-0917113712GO:0015103
GeneOntologyMolecularFunctiontransporter activity

GABRB2 CYC1 SLC6A18 GABRB3 ABCC1 NIPAL4 ATP7B SLC25A33 FLVCR1 BEST3 ABCC5 ABCC9 GJC2 ANO5 ATP8B1 PKD1L2 ATP9A CYB561A3 SLC26A1 MFSD12 SLC6A3 MFSD14A SLC6A11 PIEZO2 SLC25A12 CLCN5 NPC1L1 CACNA1H KCNT1 MCOLN3

2.64e-09128913730GO:0005215
GeneOntologyMolecularFunctiontransmembrane transporter activity

GABRB2 CYC1 SLC6A18 GABRB3 ABCC1 NIPAL4 ATP7B SLC25A33 FLVCR1 BEST3 ABCC5 ABCC9 GJC2 ANO5 PKD1L2 CYB561A3 SLC26A1 MFSD12 SLC6A3 MFSD14A SLC6A11 PIEZO2 SLC25A12 CLCN5 CACNA1H KCNT1 MCOLN3

2.73e-08118013727GO:0022857
GeneOntologyMolecularFunctionmonoatomic anion transmembrane transporter activity

GABRB2 SLC6A18 GABRB3 BEST3 ANO5 SLC26A1 SLC6A3 SLC6A11 CLCN5 MCOLN3

9.15e-0815113710GO:0008509
GeneOntologyMolecularFunctionchloride transmembrane transporter activity

GABRB2 SLC6A18 GABRB3 BEST3 ANO5 SLC26A1 SLC6A3 SLC6A11 CLCN5

2.02e-071251379GO:0015108
GeneOntologyMolecularFunctioninorganic molecular entity transmembrane transporter activity

GABRB2 CYC1 SLC6A18 GABRB3 ABCC1 NIPAL4 ATP7B BEST3 ABCC5 ABCC9 ANO5 PKD1L2 SLC26A1 SLC6A3 SLC6A11 SLC25A12 CLCN5 CACNA1H KCNT1 MCOLN3

2.39e-0775813720GO:0015318
GeneOntologyMolecularFunctionmonoatomic ion transmembrane transporter activity

GABRB2 CYC1 SLC6A18 GABRB3 NIPAL4 ATP7B BEST3 ABCC9 ANO5 PKD1L2 SLC26A1 SLC6A3 SLC6A11 PIEZO2 SLC25A12 CLCN5 CACNA1H KCNT1 MCOLN3

2.07e-0679313719GO:0015075
GeneOntologyMolecularFunctionsulfur compound transmembrane transporter activity

ABCC1 ABCC5 SLC26A1 MFSD12 SLC6A11 SLC25A12

3.81e-06611376GO:1901682
GeneOntologyMolecularFunctionactive transmembrane transporter activity

CYC1 SLC6A18 ABCC1 ATP7B ABCC5 ABCC9 CYB561A3 SLC26A1 MFSD12 SLC6A3 SLC6A11 SLC25A12 CLCN5

2.54e-0547713713GO:0022804
GeneOntologyMolecularFunctionATPase-coupled inorganic anion transmembrane transporter activity

ABCC1 ABCC5 ABCC9

3.66e-05101373GO:0043225
GeneOntologyMolecularFunctionmonoatomic anion channel activity

GABRB2 GABRB3 BEST3 ANO5 CLCN5 MCOLN3

7.74e-051031376GO:0005253
GeneOntologyMolecularFunctiongated channel activity

GABRB2 GABRB3 BEST3 ABCC9 ANO5 PIEZO2 CLCN5 CACNA1H KCNT1 MCOLN3

1.05e-0433413710GO:0022836
GeneOntologyMolecularFunctionphenanthrene-9,10-epoxide hydrolase activity

AKR7A2 AKR7L

1.40e-0431372GO:0019119
GeneOntologyMolecularFunctionphenanthrene-epoxide hydrolase activity

AKR7A2 AKR7L

1.40e-0431372GO:0019118
GeneOntologyMolecularFunctionsodium:chloride symporter activity

SLC6A18 SLC6A3 SLC6A11

2.00e-04171373GO:0015378
GeneOntologyMolecularFunctionchannel activity

GABRB2 GABRB3 BEST3 ABCC9 GJC2 ANO5 PKD1L2 PIEZO2 CLCN5 CACNA1H KCNT1 MCOLN3

2.73e-0452513712GO:0015267
GeneOntologyMolecularFunctionpassive transmembrane transporter activity

GABRB2 GABRB3 BEST3 ABCC9 GJC2 ANO5 PKD1L2 PIEZO2 CLCN5 CACNA1H KCNT1 MCOLN3

2.77e-0452613712GO:0022803
GeneOntologyMolecularFunctionmonoatomic anion:sodium symporter activity

SLC6A18 SLC6A3 SLC6A11

2.82e-04191373GO:0015373
GeneOntologyMolecularFunctionchloride channel activity

GABRB2 GABRB3 BEST3 ANO5 CLCN5

3.15e-04861375GO:0005254
GeneOntologyMolecularFunctionmonoatomic ion channel activity

GABRB2 GABRB3 BEST3 ABCC9 ANO5 PKD1L2 PIEZO2 CLCN5 CACNA1H KCNT1 MCOLN3

3.31e-0445913711GO:0005216
GeneOntologyMolecularFunctionligand-gated monoatomic ion channel activity

GABRB2 GABRB3 BEST3 ABCC9 ANO5 KCNT1 MCOLN3

3.77e-041931377GO:0015276
GeneOntologyMolecularFunctionligand-gated monoatomic anion channel activity

GABRB2 GABRB3 BEST3 ANO5

3.82e-04501374GO:0099095
GeneOntologyMolecularFunctionligand-gated channel activity

GABRB2 GABRB3 BEST3 ABCC9 ANO5 KCNT1 MCOLN3

4.27e-041971377GO:0022834
GeneOntologyMolecularFunctionchloride:monoatomic cation symporter activity

SLC6A18 SLC6A3 SLC6A11

5.06e-04231373GO:0015377
GeneOntologyMolecularFunctionmonoatomic cation transmembrane transporter activity

CYC1 SLC6A18 NIPAL4 ATP7B ABCC9 PKD1L2 SLC6A3 SLC6A11 PIEZO2 SLC25A12 CACNA1H KCNT1 MCOLN3

6.61e-0466413713GO:0008324
GeneOntologyMolecularFunctionmonoatomic anion:monoatomic cation symporter activity

SLC6A18 SLC6A3 SLC6A11

7.32e-04261373GO:0015296
GeneOntologyMolecularFunctionglutathione transmembrane transporter activity

ABCC1 ABCC5

9.59e-0471372GO:0034634
GeneOntologyMolecularFunctioninorganic cation transmembrane transporter activity

CYC1 SLC6A18 NIPAL4 ATP7B ABCC9 PKD1L2 SLC6A3 SLC6A11 SLC25A12 CACNA1H KCNT1 MCOLN3

1.30e-0362713712GO:0022890
GeneOntologyMolecularFunctionmetal ion transmembrane transporter activity

SLC6A18 NIPAL4 ATP7B ABCC9 PKD1L2 SLC6A3 SLC6A11 CACNA1H KCNT1 MCOLN3

1.40e-0346513710GO:0046873
GeneOntologyMolecularFunctionprimary active transmembrane transporter activity

CYC1 ABCC1 ATP7B ABCC5 ABCC9 CYB561A3

1.45e-031781376GO:0015399
GeneOntologyMolecularFunctionmodified amino acid transmembrane transporter activity

ABCC1 ABCC5 SLC25A12

1.48e-03331373GO:0072349
GeneOntologyMolecularFunctionprotease binding

BCL2L10 POLG ATP9A SLC6A3 BAG6 PINK1

1.57e-031811376GO:0002020
GeneOntologyMolecularFunctiontripeptide transmembrane transporter activity

ABCC1 ABCC5

1.63e-0391372GO:0042937
GeneOntologyMolecularFunctionheme transmembrane transporter activity

FLVCR1 ABCC5

1.63e-0391372GO:0015232
GeneOntologyMolecularFunctionepoxide hydrolase activity

AKR7A2 AKR7L

2.47e-03111372GO:0004301
GeneOntologyMolecularFunctionsulfur amino acid transmembrane transporter activity

MFSD12 SLC25A12

2.47e-03111372GO:0000099
GeneOntologyMolecularFunctionneutral L-amino acid transmembrane transporter activity

SLC6A18 MFSD12 SLC25A12

2.78e-03411373GO:0015175
GeneOntologyBiologicalProcessmonoatomic anion transport

GABRB2 GABRB3 ABCC1 BEST3 ABCC5 ABCC9 ANO5 ATP8B1 SLC26A1 TG CLCN5 MCOLN3

2.97e-0918313512GO:0006820
GeneOntologyBiologicalProcessmonoatomic ion transport

GABRB2 CYC1 SLC6A18 ATG5 GABRB3 ABCC1 NIPAL4 ATP7B FLVCR1 BEST3 ABCC5 ABCC9 GJC2 ANO5 ATP8B1 PKD1L2 EFHB NKAIN2 SLC26A1 TG SLC6A3 SLC6A11 PIEZO2 SLC25A12 CLCN5 UBR3 CACNA1H KCNT1 MCOLN3

1.56e-08137413529GO:0006811
GeneOntologyBiologicalProcessmonoatomic ion transmembrane transport

GABRB2 CYC1 SLC6A18 ATG5 GABRB3 ABCC1 NIPAL4 ATP7B BEST3 ABCC5 ABCC9 GJC2 ANO5 ATP8B1 PKD1L2 SLC26A1 SLC6A3 SLC6A11 PIEZO2 SLC25A12 CLCN5 UBR3 CACNA1H KCNT1 MCOLN3

5.76e-08111513525GO:0034220
GeneOntologyBiologicalProcessmonoatomic anion transmembrane transport

GABRB2 GABRB3 ABCC1 BEST3 ABCC5 ABCC9 ANO5 SLC26A1 CLCN5 MCOLN3

6.69e-0815313510GO:0098656
GeneOntologyBiologicalProcessinorganic ion transmembrane transport

GABRB2 CYC1 SLC6A18 ATG5 GABRB3 NIPAL4 ATP7B BEST3 ABCC5 ABCC9 GJC2 ANO5 PKD1L2 SLC26A1 SLC6A3 SLC6A11 SLC25A12 CLCN5 UBR3 CACNA1H KCNT1 MCOLN3

7.36e-07101713522GO:0098660
GeneOntologyBiologicalProcessinner ear development

GABRB2 ATG5 GABRB3 AHI1 HLA-E DUOX2 ATP8B1 FREM2 PLPPR4 MCOLN3

6.64e-0625313510GO:0048839
GeneOntologyBiologicalProcessear development

GABRB2 ATG5 GABRB3 AHI1 HLA-E DUOX2 ATP8B1 FREM2 PLPPR4 MCOLN3

1.87e-0528513510GO:0043583
GeneOntologyBiologicalProcesschloride transport

GABRB2 GABRB3 BEST3 ANO5 ATP8B1 SLC26A1 CLCN5

2.15e-051281357GO:0006821
GeneOntologyBiologicalProcessinorganic anion transport

GABRB2 GABRB3 BEST3 ANO5 ATP8B1 SLC26A1 TG CLCN5

2.48e-051801358GO:0015698
GeneOntologyBiologicalProcessmonoatomic cation transport

CYC1 SLC6A18 ATG5 NIPAL4 ATP7B FLVCR1 ABCC5 ABCC9 GJC2 PKD1L2 EFHB NKAIN2 SLC6A3 SLC6A11 PIEZO2 SLC25A12 UBR3 CACNA1H KCNT1 MCOLN3

6.44e-05115713520GO:0006812
GeneOntologyBiologicalProcesssulfur compound transport

ABCC1 ABCC5 SLC26A1 MFSD12 SLC6A11

6.72e-05651355GO:0072348
GeneOntologyBiologicalProcesschloride transmembrane transport

GABRB2 GABRB3 BEST3 ANO5 SLC26A1 CLCN5

9.53e-051121356GO:1902476
GeneOntologyBiologicalProcessmonoatomic cation transmembrane transport

CYC1 SLC6A18 ATG5 NIPAL4 ATP7B ABCC5 ABCC9 GJC2 PKD1L2 SLC6A3 SLC6A11 PIEZO2 SLC25A12 UBR3 CACNA1H KCNT1 MCOLN3

1.44e-0494213517GO:0098655
HumanPhenoSensory ataxia

AARS1 POLG FLVCR1 PIEZO2

2.49e-0516584HP:0010871
HumanPhenoDecreased nerve conduction velocity

AARS1 ATP7B PDK3 SPTLC2 POLG FLVCR1 GJC2 GFM2

3.26e-05112588HP:0000762
HumanPhenoAbnormality of peripheral nerve conduction

AARS1 ATP7B PDK3 SPTLC2 POLG FLVCR1 GJC2 EMILIN1 GFM2

3.85e-05149589HP:0003134
HumanPhenoAbnormal peripheral nerve morphology by anatomical site

AARS1 ATP7B PDK3 SPTLC2 POLG FLVCR1 GJC2 EMILIN1 GFM2

5.00e-05154589HP:0045010
HumanPhenoAbnormal nerve conduction velocity

AARS1 ATP7B PDK3 SPTLC2 POLG FLVCR1 GJC2 GFM2

5.06e-05119588HP:0040129
HumanPhenoAbnormal head movements

GABRB3 AARS1 GJC2 HIBCH CACNA1H

9.90e-0542585HP:0002457
DomainGABAAb_rcpt

GABRB2 GABRB3

1.55e-0431352IPR002289
DomainNA_NEUROTRAN_SYMP_2

SLC6A18 SLC6A3 SLC6A11

2.78e-04181353PS00754
DomainSNF

SLC6A18 SLC6A3 SLC6A11

3.29e-04191353PF00209
DomainNa/ntran_symport

SLC6A18 SLC6A3 SLC6A11

3.29e-04191353IPR000175
DomainNA_NEUROTRAN_SYMP_1

SLC6A18 SLC6A3 SLC6A11

3.29e-04191353PS00610
DomainNA_NEUROTRAN_SYMP_3

SLC6A18 SLC6A3 SLC6A11

3.29e-04191353PS50267
DomainGal_Lectin

ADGRL1 PKD1L2

5.11e-0451352PF02140
DomainLectin_gal-bd_dom

ADGRL1 PKD1L2

5.11e-0451352IPR000922
DomainSUEL_LECTIN

ADGRL1 PKD1L2

5.11e-0451352PS50228
DomainADAM_spacer1

ADAMTS1 ADAMTS6 ADAMTS15

5.88e-04231353IPR010294
DomainADAM_spacer1

ADAMTS1 ADAMTS6 ADAMTS15

5.88e-04231353PF05986
DomainABC_membrane

ABCC1 ABCC5 ABCC9

6.69e-04241353PF00664
DomainPeptidase_M12B_ADAM-TS

ADAMTS1 ADAMTS6 ADAMTS15

6.69e-04241353IPR013273
DomainABC_TM1F

ABCC1 ABCC5 ABCC9

1.06e-03281353PS50929
DomainABC1_TM_dom

ABCC1 ABCC5 ABCC9

1.06e-03281353IPR011527
Domain-

ATP7B ATP8B1 ATP9A

1.57e-033213533.40.1110.10
Domain-

ATP7B ATP8B1 ATP9A

1.57e-033213532.70.150.10
DomainGPS

ADGRL1 PKD1L2 ADGRL4

1.88e-03341353SM00303
DomainATPase_P-typ_cyto_domN

ATP7B ATP8B1 ATP9A

2.04e-03351353IPR023299
DomainGPS

ADGRL1 PKD1L2 ADGRL4

2.04e-03351353PF01825
DomainATPase_P-typ_P_site

ATP7B ATP8B1 ATP9A

2.21e-03361353IPR018303
DomainP_typ_ATPase

ATP7B ATP8B1 ATP9A

2.21e-03361353IPR001757
DomainGPS

ADGRL1 PKD1L2 ADGRL4

2.21e-03361353PS50221
DomainATPASE_E1_E2

ATP7B ATP8B1 ATP9A

2.21e-03361353PS00154
DomainATPase_P-typ_transduc_dom_A

ATP7B ATP8B1 ATP9A

2.40e-03371353IPR008250
DomainGPS

ADGRL1 PKD1L2 ADGRL4

2.40e-03371353IPR000203
DomainE1-E2_ATPase

ATP7B ATP8B1 ATP9A

2.40e-03371353PF00122
DomainGAIN_dom_N

ADGRL1 ADGRL4

2.73e-03111352IPR032471
DomainPKD_channel

PKD1L2 MCOLN3

2.73e-03111352PF08016
DomainGAIN

ADGRL1 ADGRL4

2.73e-03111352PF16489
DomainPKD1_2_channel

PKD1L2 MCOLN3

2.73e-03111352IPR013122
DomainPep_M12B_propep

ADAMTS1 ADAMTS6 ADAMTS15

2.79e-03391353PF01562
DomainPeptidase_M12B_N

ADAMTS1 ADAMTS6 ADAMTS15

2.79e-03391353IPR002870
DomainDISINTEGRIN_1

ADAMTS1 ADAMTS6 ADAMTS15

3.00e-03401353PS00427
DomainReprolysin

ADAMTS1 ADAMTS6 ADAMTS15

3.00e-03401353PF01421
DomainADAM_MEPRO

ADAMTS1 ADAMTS6 ADAMTS15

3.00e-03401353PS50215
DomainDISINTEGRIN_2

ADAMTS1 ADAMTS6 ADAMTS15

3.00e-03401353PS50214
DomainPeptidase_M12B

ADAMTS1 ADAMTS6 ADAMTS15

3.00e-03401353IPR001590
DomainDisintegrin_dom

ADAMTS1 ADAMTS6 ADAMTS15

3.22e-03411353IPR001762
DomainABC_transporter_CS

ABCC1 ABCC5 ABCC9

3.45e-03421353IPR017871
DomainOLF

ADGRL1 OLFML3

3.84e-03131352PF02191
DomainOLF

ADGRL1 OLFML3

3.84e-03131352PS51132
DomainOlfac-like_dom

ADGRL1 OLFML3

3.84e-03131352IPR003112
DomainOLF

ADGRL1 OLFML3

3.84e-03131352SM00284
DomainP_typ_ATPase_c

ATP8B1 ATP9A

4.46e-03141352IPR032630
DomainP-type_ATPase_N

ATP8B1 ATP9A

4.46e-03141352IPR032631
DomainP-type_ATPase_IV

ATP8B1 ATP9A

4.46e-03141352IPR006539
DomainPhoLip_ATPase_C

ATP8B1 ATP9A

4.46e-03141352PF16212
DomainPhoLip_ATPase_N

ATP8B1 ATP9A

4.46e-03141352PF16209
DomainABC_tran

ABCC1 ABCC5 ABCC9

5.04e-03481353PF00005
DomainABC_TRANSPORTER_2

ABCC1 ABCC5 ABCC9

5.04e-03481353PS50893
DomainABC_TRANSPORTER_1

ABCC1 ABCC5 ABCC9

5.34e-03491353PS00211
DomainABC_transporter-like

ABCC1 ABCC5 ABCC9

5.65e-03501353IPR003439
DomainNADP_OxRdtase_dom

AKR7A2 AKR7L

6.57e-03171352IPR023210
DomainCarboxyPept-like_regulatory

CPD TENM4

6.57e-03171352IPR008969
DomainAldo_ket_red

AKR7A2 AKR7L

6.57e-03171352PF00248
DomainAldo/ket_red/Kv-b

AKR7A2 AKR7L

6.57e-03171352IPR001395
PathwayREACTOME_TRANSPORT_OF_SMALL_MOLECULES

SLC6A18 ABCC1 NIPAL4 ATP7B FLVCR1 BEST3 ABCC5 ABCC9 ANO5 ATP8B1 ATP9A SLC26A1 SLC6A3 SLC6A11 CLCN5 MCOLN3

3.69e-0568110416MM14985
PathwayREACTOME_TRANSPORT_OF_SMALL_MOLECULES

SLC6A18 ABCC1 NIPAL4 ATP7B FLVCR1 BEST3 ABCC5 ABCC9 ANO5 ATP8B1 ATP9A SLC26A1 SLC6A3 SLC6A11 CLCN5 MCOLN3

9.27e-0573610416M27287
Pubmed

Irisin Mediates Effects on Bone and Fat via αV Integrin Receptors.

CYC1 ABCC1 AARS1 ADAMTS1 PDK3 SPTLC2 TM9SF1 HLA-E LAMB1 NIPSNAP3A CPD OLFML3 GFM2 AKR7A2 LRPPRC RBM12 GANAB SLC25A12 CLCN5 AKR7L TMX4 BAG6 RPL11

1.65e-0814511392330550785
Pubmed

Prediction of the coding sequences of unidentified human genes. XI. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro.

LARP1 GRAMD4 EPM2AIP1 RBM12 SEL1L3 KBTBD11

3.39e-0610113969872452
Pubmed

LMBR1L regulates lymphopoiesis through Wnt/β-catenin signaling.

CYC1 ABCC1 AARS1 ADAMTS1 SPTLC2 TM9SF1 FLVCR1 CPD ATP9A NSUN2 LRPPRC GANAB SLC25A12 SEC23IP BAG6

5.97e-069421391531073040
Pubmed

Quantitative high-confidence human mitochondrial proteome and its dynamics in cellular context.

CYC1 ATP7B PDK3 SLC25A33 POLG ADCK1 NIPSNAP3A NSUN2 GFM2 AKR7A2 LRPPRC CRYZ SLC25A12 HIBCH CSKMT PINK1

1.33e-0511361391634800366
Pubmed

The mouse Rhl1 and Rhag genes: sequence, organization, expression, and chromosomal mapping.

HLA-E AKR7A2 AKR7L

1.34e-0512139310495887
Pubmed

Chronic treatment with the complex I inhibitor MPP+ depletes endogenous PTEN-induced kinase 1 (PINK1) via up-regulation of Bcl-2-associated athanogene 6 (BAG6).

BAG6 PINK1

1.59e-052139232332095
Pubmed

β-cell proliferation is associated with increased A-type γ-aminobutyric acid receptor expression in pancreatectomized mice.

GABRB2 GABRB3

1.59e-052139223486367
Pubmed

Sedation and anesthesia mediated by distinct GABA(A) receptor isoforms.

GABRB2 GABRB3

1.59e-052139213679430
Pubmed

Increased expression of GABA(A) receptor beta-subunits in the hippocampus of patients with temporal lobe epilepsy.

GABRB2 GABRB3

1.59e-052139214503638
Pubmed

Direct binding of GABAA receptor β2 and β3 subunits to gephyrin.

GABRB2 GABRB3

1.59e-052139223205938
Pubmed

Leukemia inhibitory factor regulates trafficking of T-type Ca2+ channels.

LIF CACNA1H

1.59e-052139221178106
Pubmed

Effects of maturation on RNA transcription and protein expression of four MRP genes in human placenta and in BeWo cells.

ABCC1 ABCC5

1.59e-052139212646196
Pubmed

Estrous cycle variations in GABA(A) receptor phosphorylation enable rapid modulation by anabolic androgenic steroids in the medial preoptic area.

GABRB2 GABRB3

1.59e-052139222989919
Pubmed

ATPase Class I Type 8B Member 1 and protein kinase C zeta induce the expression of the canalicular bile salt export pump in human hepatocytes.

ATP8B1 PRKCZ

1.59e-052139219809379
Pubmed

Attenuating GABA(A) receptor signaling in dopamine neurons selectively enhances reward learning and alters risk preference in mice.

GABRB3 SLC6A3

1.59e-052139222114279
Pubmed

Unbiased Profiling of the Human Proinsulin Biosynthetic Interaction Network Reveals a Role for Peroxiredoxin 4 in Proinsulin Folding.

CYC1 PDK3 LARP1 DUOX2 NSUN2 ALKBH5 GRAMD4 GANAB HIBCH RPL11

1.87e-054641391032457219
Pubmed

Construction of a multi-functional cDNA library specific for mouse pancreatic islets and its application to microarray.

ABCC1 ADAMTS1 HLA-E ATP8B1 CFB LIF SLC25A12 SEL1L3 RPL11

1.97e-05371139915747579
Pubmed

The interactome of intact mitochondria by cross-linking mass spectrometry provides evidence for coexisting respiratory supercomplexes.

CYC1 PDK3 ADCK1 AKR7A2 LRPPRC CRYZ SLC25A12 HIBCH AKR7L

2.47e-05382139929222160
Pubmed

Evolutionary trajectory of receptor binding specificity and promiscuity of the spike protein of SARS-CoV-2.

CYC1 CFB TG

2.74e-0515139336305765
Pubmed

Delineating WWOX Protein Interactome by Tandem Affinity Purification-Mass Spectrometry: Identification of Top Interactors and Key Metabolic Pathways Involved.

PDK3 SPTLC2 NSUN2 TXNDC11 GANAB SLC25A12 SEC23IP

2.84e-05217139730619736
Pubmed

Modulatory effects of plant phenols on human multidrug-resistance proteins 1, 4 and 5 (ABCC1, 4 and 5).

ABCC1 ABCC5

4.75e-053139216156793
Pubmed

Transgenic overexpression of furin increases epileptic susceptibility.

GABRB2 GABRB3

4.75e-053139230333479
Pubmed

[Purification of recombinant AKR7A5 protein and measurement of substrate specificity of AKR7A5 towards naphthoquinone and its derivatives].

AKR7A2 AKR7L

4.75e-053139222863590
Pubmed

Endogenous Parkin Preserves Dopaminergic Substantia Nigral Neurons following Mitochondrial DNA Mutagenic Stress.

POLG SLC6A3

4.75e-053139226182419
Pubmed

The membrane protein ATPase class I type 8B member 1 signals through protein kinase C zeta to activate the farnesoid X receptor.

ATP8B1 PRKCZ

4.75e-053139218668687
Pubmed

BAG6 promotes PINK1 signaling pathway and is essential for mitophagy.

BAG6 PINK1

4.75e-053139233522017
Pubmed

Characterisation of a novel mouse liver aldo-keto reductase AKR7A5.

AKR7A2 AKR7L

4.75e-053139212123834
Pubmed

Genotypes and phenotypes of congenital goitre and hypothyroidism caused by mutations in dual oxidase 2 genes.

DUOX2 TG

4.75e-053139224735383
Pubmed

Aldo-keto reductase 7A5 (AKR7A5) attenuates oxidative stress and reactive aldehyde toxicity in V79-4 cells.

AKR7A2 AKR7L

4.75e-053139224590062
Pubmed

GABAA receptor beta 1, beta 2, and beta 3 subunits: comparisons in DBA/2J and C57BL/6J mice.

GABRB2 GABRB3

4.75e-05313927893750
Pubmed

Differential expression of GABAA/benzodiazepine receptor beta 1, beta 2, and beta 3 subunit mRNAs in the developing mouse cerebellum.

GABRB2 GABRB3

4.75e-05313921282920
Pubmed

The multidrug resistance protein family.

ABCC1 ABCC5

4.75e-053139210581366
Pubmed

Conjugate export pumps of the multidrug resistance protein (MRP) family: localization, substrate specificity, and MRP2-mediated drug resistance.

ABCC1 ABCC5

4.75e-053139210581368
Pubmed

A family of drug transporters: the multidrug resistance-associated proteins.

ABCC1 ABCC5

4.75e-053139210944550
Pubmed

The ADAMTS (A Disintegrin and Metalloproteinase with Thrombospondin motifs) family.

ADAMTS1 ADAMTS6

4.75e-053139226025392
Pubmed

Protrudin modulates seizure activity through GABAA receptor regulation.

GABRB2 GABRB3

4.75e-053139231772151
Pubmed

Novel homodimeric and heterodimeric rat gamma-hydroxybutyrate synthases that associate with the Golgi apparatus define a distinct subclass of aldo-keto reductase 7 family proteins.

AKR7A2 AKR7L

4.75e-053139212071861
Pubmed

Mouse aldo-keto reductase AKR7A5 protects V79 cells against 4-hydroxynonenal-induced apoptosis.

AKR7A2 AKR7L

4.75e-053139216919859
Pubmed

Time and concentration dependency of P-gp, MRP1 and MRP5 induction in response to gemcitabine uptake in Capan-2 pancreatic cancer cells.

ABCC1 ABCC5

4.75e-053139225564970
Pubmed

AKR7A5 knockout promote acute liver injury by inducing inflammatory response, oxidative stress and apoptosis in mice.

AKR7A2 AKR7L

4.75e-053139239365156
Pubmed

Double deletion of PINK1 and Parkin impairs hepatic mitophagy and exacerbates acetaminophen-induced liver injury in mice.

ATG5 PINK1

4.75e-053139230818124
Pubmed

Expression and distribution of GABAA receptor subtypes in human alcoholic cerebral cortex.

GABRB2 GABRB3

4.75e-053139211085308
Pubmed

A novel histochemistry assay to assess and quantify focal cytochrome c oxidase deficiency.

POLG LRPPRC

4.75e-053139229660116
Pubmed

GABAA receptor beta subunit mRNA expression in the human alcoholic brain.

GABRB2 GABRB3

4.75e-053139215337300
Pubmed

GABA neurotransmitter signaling in the developing mouse lens: dynamic regulation of components and functionality.

GABRB2 GABRB3 SLC6A11

4.88e-0518139318985723
Pubmed

A Multipronged Unbiased Strategy Guides the Development of an Anti-EGFR/EPHA2-Bispecific Antibody for Combination Cancer Therapy.

ABCC1 FLVCR1 ADGRL1 RICTOR CPD ITGA7 LRPPRC GANAB SEC23IP

5.25e-05421139936976175
Pubmed

The repertoire of solute carriers of family 6: identification of new human and rodent genes.

SLC6A18 SLC6A3 SLC6A11

7.88e-0521139316125675
Pubmed

A mitochondrial protein compendium elucidates complex I disease biology.

CYC1 PDK3 SPTLC2 SLC25A33 POLG ADCK1 NIPSNAP3A GFM2 AKR7A2 LRPPRC SLC25A12 HIBCH AKR7L PINK1

8.25e-0510471391418614015
Pubmed

Aflatoxin B1 aldehyde reductase (AFAR) genes cluster at 1p35-1p36.1 in a region frequently altered in human tumour cells.

AKR7A2 AKR7L

9.47e-054139212879023
Pubmed

Characterization of P4 ATPase Phospholipid Translocases (Flippases) in Human and Rat Pancreatic Beta Cells: THEIR GENE SILENCING INHIBITS INSULIN SECRETION.

ATP8B1 ATP9A

9.47e-054139226240149
Pubmed

LERK-7: a ligand of the Eph-related kinases is developmentally regulated in the brain.

EFNA5 EPHB1

9.47e-05413929245480
Pubmed

Laminin-111 restores regenerative capacity in a mouse model for alpha7 integrin congenital myopathy.

LAMB1 ITGA7

9.47e-054139219074617
Pubmed

Longitudinal tracking of neuronal mitochondria delineates PINK1/Parkin-dependent mechanisms of mitochondrial recycling and degradation.

SLC6A3 PINK1

9.47e-054139234362731
Pubmed

Differential cell surface expression of GABAA receptor alpha1, alpha6, beta2 and beta3 subunits in cultured mouse cerebellar granule cells influence of cAMP-activated signalling.

GABRB2 GABRB3

9.47e-054139211902122
Pubmed

Parkin and PINK1 mitigate STING-induced inflammation.

POLG PINK1

9.47e-054139230135585
Pubmed

Atg5-dependent autophagy contributes to the development of acute myeloid leukemia in an MLL-AF9-driven mouse model.

ATG5 MLLT3

9.47e-054139227607576
Pubmed

Celecoxib upregulates multidrug resistance proteins in colon cancer: lack of synergy with standard chemotherapy.

ABCC1 ABCC5

9.47e-054139218690847
Pubmed

PINK1 phosphorylates Drp1S616 to regulate mitophagy-independent mitochondrial dynamics.

ATG5 PINK1

9.47e-054139232484300
Pubmed

Differential assembly diversifies GABAA receptor structures and signalling.

GABRB2 GABRB3

9.47e-054139235355020
Pubmed

Inhibitory synapse formation in a co-culture model incorporating GABAergic medium spiny neurons and HEK293 cells stably expressing GABAA receptors.

GABRB2 GABRB3

9.47e-054139225489750
Pubmed

cGMP transport by vesicles from human and mouse erythrocytes.

ABCC1 ABCC5

9.47e-054139217229149
Pubmed

GABAA Receptors and the Diversity in their Structure and Pharmacology.

GABRB2 GABRB3

9.47e-054139228528665
Pubmed

A53T human α-synuclein overexpression in transgenic mice induces pervasive mitochondria macroautophagy defects preceding dopamine neuron degeneration.

SLC6A3 PINK1

9.47e-054139225609609
Pubmed

Dopamine neuron morphology and output are differentially controlled by mTORC1 and mTORC2.

RICTOR SLC6A3

9.47e-054139235881440
Pubmed

Human skeletal muscle drug transporters determine local exposure and toxicity of statins.

ABCC1 ABCC5

9.47e-054139219940267
Pubmed

Differential, strain-specific cellular and subcellular distribution of multidrug transporters in murine choroid plexus and blood-brain barrier.

ABCC1 ABCC5

9.47e-054139216361063
Pubmed

Identification of 18 mouse ABC genes and characterization of the ABC superfamily in Mus musculus.

ABCC1 ABCC5 ABCC9

1.04e-0423139310708515
Pubmed

Avoiding mouse traps in schizophrenia genetics: lessons and promises from current and emerging mouse models.

GABRB2 AHI1 RTN4R

1.19e-0424139321821099
Pubmed

Transporter gene expression in lactating and nonlactating human mammary epithelial cells using real-time reverse transcription-polymerase chain reaction.

ABCC1 ABCC5

1.57e-045139212388627
Pubmed

Laminin-111 protein therapy prevents muscle disease in the mdx mouse model for Duchenne muscular dystrophy.

LAMB1 ITGA7

1.57e-045139219416897
Pubmed

Differential expression of GABAA/benzodiazepine receptor subunit mRNAs and ligand binding sites in mouse cerebellar neurons following in vivo ethanol administration: an autoradiographic analysis.

GABRB2 GABRB3

1.57e-04513927643102
Pubmed

mTORC2 phosphorylates protein kinase Cζ to regulate its stability and activity.

RICTOR PRKCZ

1.57e-045139224375676
Pubmed

Novel protein complexes containing autophagy and UPS components regulate proteasome-dependent PARK2 recruitment onto mitochondria and PARK2-PARK6 activity during mitophagy.

ATG5 PINK1

1.57e-045139236357363
Pubmed

Multiple members of a third subfamily of P-type ATPases identified by genomic sequences and ESTs.

ATP8B1 ATP9A

1.57e-04513929548971
Pubmed

GABAA receptors: structure, function, pharmacology, and related disorders.

GABRB2 GABRB3

1.57e-045139234417930
Pubmed

Expression of ephrinA5 during development and potential involvement in the guidance of the mesostriatal pathway.

SLC6A3 EFNA5

1.57e-045139219576892
Pubmed

Metalloproteinase Adamts16 Is Required for Proper Closure of the Optic Fissure.

ADAMTS6 ADAMTS15

1.57e-045139229625437
Pubmed

GABA uptake transporters support dopamine release in dorsal striatum with maladaptive downregulation in a parkinsonism model.

SLC6A3 SLC6A11

1.57e-045139233009395
Pubmed

The brefeldin A-inhibited GDP/GTP exchange factor 2, a protein involved in vesicular trafficking, interacts with the beta subunits of the GABA receptors.

GABRB2 GABRB3

1.57e-045139215198677
Pubmed

Identification of a novel partner of duox: EFP1, a thioredoxin-related protein.

DUOX2 TXNDC11

1.57e-045139215561711
Pubmed

γ-Aminobutyric Acid Type A (GABAA) Receptor Subunits Play a Direct Structural Role in Synaptic Contact Formation via Their N-terminal Extracellular Domains.

GABRB2 GABRB3

1.57e-045139227129275
Pubmed

Involvement of gp130-associated cytokine signaling in Müller cell activation following optic nerve lesion.

LIF LRPPRC

1.57e-045139220091786
Pubmed

Efflux protein expression in human stem cell-derived retinal pigment epithelial cells.

ABCC1 ABCC5

1.57e-045139222272278
Pubmed

Proteomic identification of common SCF ubiquitin ligase FBXO6-interacting glycoproteins in three kinds of cells.

CYC1 EIF3E LAMB1 CPD TXNDC11 LRPPRC GANAB SLC25A12 SEL1L3 TMEM131

1.88e-046131391022268729
Pubmed

Neuron-specific protein network mapping of autism risk genes identifies shared biological mechanisms and disease-relevant pathologies.

GABRB2 GABRB3 PDK3 ADCK1 ADGRL1 RICTOR AKR7A2 SLC6A11 LRPPRC TENM4 PLPPR4 AKR7L TMX4 UBR3

1.98e-0411391391436417873
Pubmed

KCTD13-mediated ubiquitination and degradation of GluN1 regulates excitatory synaptic transmission and seizure susceptibility.

CYC1 GABRB3 LARP1 ADGRL1 GJC2 ATP9A GRM2 HAPLN1 RIN1 LRPPRC TENM4 SLC25A12 PLPPR4 KBTBD11 PCDH1 RPL11

2.01e-0414311391637142655
Pubmed

Chr21 protein-protein interactions: enrichment in proteins involved in intellectual disability, autism, and late-onset Alzheimer's disease.

ATG5 AARS1 ADAMTS1 POLG LAMB1 ABCC5 EYA3 NSUN2 TXNDC11 SEC23IP SHARPIN MLLT3 TMEM131 REPS2 PINK1

2.03e-0412851391535914814
Pubmed

SERBP1 Promotes Stress Granule Clearance by Regulating 26S Proteasome Activity and G3BP1 Ubiquitination and Protects Male Germ Cells from Thermostimuli Damage.

ABCC1 AARS1 SPTLC2 EIF3E EYA3 PPCS NSUN2 LRPPRC GANAB SLC25A12 SEC23IP RPL11

2.22e-048781391237223481
Pubmed

A new cytosolic pathway from a Parkinson disease-associated kinase, BRPK/PINK1: activation of AKT via mTORC2.

RICTOR PINK1

2.35e-046139221177249
Pubmed

Duox expression and related H2O2 measurement in mouse thyroid: onset in embryonic development and regulation by TSH in adult.

DUOX2 TG

2.35e-046139217332529
Pubmed

The GABAA Receptor β Subunit Is Required for Inhibitory Transmission.

GABRB2 GABRB3

2.35e-046139229706582
Pubmed

Integrins as receptors for laminins.

LAMB1 ITGA7

2.35e-046139211054877
Pubmed

Palmitoylation of gephyrin controls receptor clustering and plasticity of GABAergic synapses.

GABRB2 GABRB3

2.35e-046139225025157
Pubmed

Genetic, personality, and environmental predictors of drug use in adolescents.

GABRB3 SLC6A3

2.35e-046139219717274
Pubmed

Migration defects of cdk5(-/-) neurons in the developing cerebellum is cell autonomous.

GABRB2 GABRB3

2.35e-046139210407039
Pubmed

Evolution of GABA(A) receptor diversity in the human genome.

GABRB2 GABRB3

2.35e-046139210023064
Pubmed

Identification of new ciliary signaling pathways in the brain and insights into neurological disorders.

GABRB2 FLVCR1 ADGRL1 ATP9A GRM2 PIP5K1C TENM4 PLPPR4

2.36e-04405139838187761
Pubmed

Prediction of the coding sequences of mouse homologues of KIAA gene: II. The complete nucleotide sequences of 400 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.

ADGRL1 ATP9A PIP5K1C EPM2AIP1 GANAB TENM4 SEL1L3 CACNA1H

2.44e-04407139812693553
Pubmed

Proline-rich sequence recognition: II. Proteomics analysis of Tsg101 ubiquitin-E2-like variant (UEV) interactions.

LARP1 SEC23IP BAG6

2.85e-0432139319542561
Pubmed

Semaphorin 3E/PlexinD1 signaling is required for cardiac ventricular compaction.

ADAMTS1 IRX3 ADAMTS15

2.85e-0432139331434798
GeneFamilyATP binding cassette subfamily C

ABCC1 ABCC5 ABCC9

3.87e-0513953807
GeneFamilyADAM metallopeptidases with thrombospondin type 1 motif

ADAMTS1 ADAMTS6 ADAMTS15

1.28e-041995350
GeneFamilyAdhesion G protein-coupled receptors, subfamily L

ADGRL1 ADGRL4

1.63e-044952918
CoexpressionMANNO_MIDBRAIN_NEUROTYPES_HGABA

GABRB2 GABRB3 COL6A6 ABCC5 ADGRL1 RICTOR ANO5 IRX3 ATP9A NKAIN2 PIEZO2 EFNA5 SLC25A12 PLPPR4 KBTBD11 MLLT3 PRKCZ CCDC17 PCDH1 EPHB1

1.45e-06110613820M39071
CoexpressionGSE24972_WT_VS_IRF8_KO_SPLEEN_FOLLICULAR_BCELL_DN

AHI1 C11orf54 NIPSNAP3A NSUN2 CFB TENM4 RBPMS2 TMEM131

1.14e-052001388M8096
CoexpressionMILI_PSEUDOPODIA_HAPTOTAXIS_DN

ABCC1 SPTLC2 TM9SF1 POLG HLA-E LAMB1 ABCC5 CPD GRAMD4 TXNDC11 MFSD14A LIF GANAB PCDH1

2.16e-0570313814MM1055
CoexpressionAtlaskidney_e15.5_Podocyte_MafB_top-relative-expression-ranked_1000

GABRB2 ADAMTS1 PDK3 TMEM176A ATP8B1 OLFML3 CFB ADGRL4 DOCK5 FREM2 CRYZ PIEZO2 EFNA5 CLCN5 SEL1L3 KBTBD11 CYP7B1

1.65e-0581413517gudmap_kidney_e15.5_Podocyte_MafB_1000
ToppCellEndothelial_cells-Endothelial-B|Endothelial_cells / lung cells shred on cell class, cell subclass, sample id

GJC2 EMILIN1 DOCK5 LIF PIEZO2 EFNA5 KBTBD11 ADAMTS15 PRKCZ

1.18e-08196139936f95f9ef74eb951e41ef46fd136ceaef45208fc
ToppCellcellseq-Mesenchymal-Fibroblastic-Fibroblastic_2-AF1|cellseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

COL6A6 ADAMTS1 TMEM176A LAMB1 EMILIN1 OLFML3 PIEZO2 CYP7B1 MCOLN3

1.29e-081981399f1374f7a50244d59c766ac41f44c08c9117407d2
ToppCelldistal-mesenchymal-Alveolar_Fibroblast-2|distal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

COL6A6 ADAMTS1 TMEM176A LAMB1 EMILIN1 OLFML3 PIEZO2 CYP7B1 MCOLN3

1.35e-08199139928c1722deef3b8347371c7359be7c64b95780de3
ToppCell3'-Broncho-tracheal-Endothelial-Blood_vessel_EC-pulmonary_artery_endothelial_cell-EC_arterial-EC_arterial_L.2.4.0.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

ADAMTS1 HLA-E GRM2 NKAIN2 ADGRL4 PLPPR4 TIE1 ADAMTS6

7.79e-08174139818ab52d8bbca0507fee220e0c4fc765fc47dda34
ToppCelltumor_Lung-Fibroblasts-Pericytes|tumor_Lung / Location, Cell class and cell subclass

ADAMTS1 LAMB1 ABCC9 ITGA7 PLPPR4 RBPMS2 CACNA1H PCDH1

1.15e-071831398a03dd563af9b15cb1f5de5732a229405a9f82d84
ToppCell5'-Parenchyma_lung-Mesenchymal-Fibroblastic-fibroblastic_type_2-Alveolar_fibroblasts-Alveolar_fibroblasts_L.2.1.1.1|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

COL6A6 ADAMTS1 LAMB1 EMILIN1 OLFML3 PIEZO2 PLPPR4 CYP7B1

1.30e-0718613985473283fb95cee556b1f6934cf72169b676b5bcc
ToppCell367C-Fibroblasts-Fibroblast-C_(Myofibroblast)-|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)

COL6A6 TMEM176A LAMB1 EMILIN1 OLFML3 PIEZO2 CYP7B1 MCOLN3

1.94e-0719613986730743cf088c419ccc2d28765769fc09d3ba6a7
ToppCell367C-Fibroblasts-Fibroblast-C_(Myofibroblast)|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)

COL6A6 TMEM176A LAMB1 EMILIN1 OLFML3 PIEZO2 CYP7B1 MCOLN3

1.94e-07196139821dab89f3699037138a9c7a0e4dc98739a9fad9c
ToppCell3'-Parenchyma_lung-Mesenchymal-Fibroblastic-fibroblastic_type_2|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

COL6A6 ADAMTS1 LAMB1 EMILIN1 OLFML3 PIEZO2 CYP7B1 MCOLN3

1.94e-0719613989737a5f006d37b549f281e1863aca558e1e4dc99
ToppCell3'-Parenchyma_lung-Mesenchymal-Fibroblastic-fibroblastic_type_2-Alveolar_fibroblasts|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

COL6A6 ADAMTS1 LAMB1 EMILIN1 OLFML3 PIEZO2 CYP7B1 MCOLN3

1.94e-071961398cecf82cd5e0a3835d655f5e7478578674a63ce25
ToppCell3'-Parenchyma_lung-Mesenchymal-Fibroblastic-fibroblastic_type_2-Alveolar_fibroblasts-Alveolar_fibroblasts_L.2.1.1.1|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

COL6A6 ADAMTS1 LAMB1 EMILIN1 OLFML3 PIEZO2 PLPPR4 CYP7B1

2.02e-07197139894a9603cbd3516fbcce871909693b88f20d41713
ToppCelltumor_Lung-Endothelial_cells-Lymphatic_ECs|Endothelial_cells / Location, Cell class and cell subclass

GJC2 EMILIN1 DOCK5 PIEZO2 EFNA5 KBTBD11 PRKCZ EPHB1

2.02e-071971398a05237ee6d31d9eab491dd7007859d6285cf1424
ToppCellnormal_Lung-Fibroblasts-COL13A1+_matrix_FBs|normal_Lung / Location, Cell class and cell subclass

COL6A6 TMEM176A LAMB1 EMILIN1 OLFML3 FZD1 PIEZO2 MCOLN3

2.02e-0719713986c57ab2efb8363828e24211c4d45e58bb73a9a4d
ToppCellcellseq-Mesenchymal-Fibroblastic-Fibroblastic_2|cellseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

COL6A6 ADAMTS1 LAMB1 EMILIN1 OLFML3 PIEZO2 CYP7B1 MCOLN3

2.18e-07199139866a79732caf2f04c09b4d9832377aa01ca477677
ToppCellBronchial-10x5prime-Endothelial-Endothelia_vascular-VE_systemic_arterial|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

ADAMTS1 LAMB1 NKAIN2 ADGRL4 TIE1 ADAMTS6 NPC1L1 PCDH1

2.18e-0719913986a2943a23fdd2ec814662db7c21a0d6804a6cbbc
ToppCell343B-Fibroblasts-Fibroblast-G|343B / Donor, Lineage, Cell class and subclass (all cells)

COL6A6 ADAMTS1 TMEM176A LAMB1 EMILIN1 OLFML3 PIEZO2 MCOLN3

2.18e-071991398f4b6c095cbe7a38b310adc49be4069e4d56e6a66
ToppCell343B-Fibroblasts-Fibroblast-G-|343B / Donor, Lineage, Cell class and subclass (all cells)

COL6A6 ADAMTS1 TMEM176A LAMB1 EMILIN1 OLFML3 PIEZO2 MCOLN3

2.18e-0719913989c6d1c328bfbb6547f4c7bb2a784576a56bd72af
ToppCellmedial-mesenchymal-Alveolar_Fibroblast|medial / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

COL6A6 ADAMTS1 TMEM176A EMILIN1 OLFML3 PIEZO2 CYP7B1 MCOLN3

2.27e-072001398c22cbfecee00183dd4be678f116ab9fd9ad0a4dd
ToppCellLung_Parenchyma-Severe-Mesenchymal-Mesenchymal-Fibroblasts-1|Severe / Location, Disease Group, Cell group, Cell class (2021.03.09)

COL6A6 TMEM176A LAMB1 ABCC9 EMILIN1 OLFML3 PIEZO2 CYP7B1

2.27e-072001398c3d4ce70ab51d74c9fe2f5864e52a4a9d7570e10
ToppCellParenchyma_Control_(B.)-Stromal-TX-Fibroblasts-1|Parenchyma_Control_(B.) / Sample group, Lineage and Cell type

COL6A6 ADAMTS1 LAMB1 EMILIN1 OLFML3 PIEZO2 PLPPR4 CYP7B1

2.27e-072001398aa1a35dcca3b799241eef4237f6eb94660e019f0
ToppCellmedial-2-mesenchymal-Alveolar_Fibroblast|2 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

COL6A6 ADAMTS1 TMEM176A EMILIN1 OLFML3 PIEZO2 CYP7B1 MCOLN3

2.27e-072001398cc6062dac07916c29091fc6bee2b864d29e6525b
ToppCellLung_Parenchyma-Severe-Mesenchymal-Mesenchymal-Fibroblasts-1-|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

COL6A6 TMEM176A LAMB1 ABCC9 EMILIN1 OLFML3 PIEZO2 CYP7B1

2.27e-072001398137f8f9d255c66336d4f8b44b2e3f3de721f2bf0
ToppCellLung_Parenchyma-Control-Mesenchymal-Mesenchymal-Fibroblasts-1|Control / Location, Disease Group, Cell group, Cell class (2021.03.09)

COL6A6 ADAMTS1 LAMB1 EMILIN1 OLFML3 PIEZO2 PLPPR4 CYP7B1

2.27e-072001398a510deaada669e690329183e18df02870bd204b3
ToppCellmedial-mesenchymal-Alveolar_Fibroblast-2|medial / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

COL6A6 ADAMTS1 TMEM176A EMILIN1 OLFML3 PIEZO2 CYP7B1 MCOLN3

2.27e-0720013985c0716bf375c8158f7dc2c82bf5eaf37af594dd0
ToppCellParenchyma_COVID-19-Stromal-TX-Fibroblasts-1|Parenchyma_COVID-19 / Sample group, Lineage and Cell type

COL6A6 TMEM176A LAMB1 ABCC9 EMILIN1 OLFML3 PIEZO2 CYP7B1

2.27e-07200139825d3865aa2ced11a5ed40013e83b47d942fdf582
ToppCellLung_Parenchyma-Control-Mesenchymal-Mesenchymal-Fibroblasts-1-|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

COL6A6 ADAMTS1 LAMB1 EMILIN1 OLFML3 PIEZO2 PLPPR4 CYP7B1

2.27e-072001398dd4228cbed8a4395166a6332e08d44d88bebe3b9
ToppCell5'-GW_trimst-2-SmallIntestine-Mesenchymal-fibroblastic-Stromal_1_(CCL11+)|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

MYH8 COL6A6 TMEM176A HAPLN1 RIN1 CYP7B1 CCDC17

1.18e-061721397afa36501d48b1456c511fa0d5d326ec05bdc380f
ToppCell5'-Parenchyma_lung-Mesenchymal-Mesenchymal_Myocytic-pericyte_cell-Pericytes-Pericytes_L.2.3.3.0|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

GABRB2 ADAMTS1 LAMB1 ABCC9 HAPLN1 HOXA6 CACNA1H

1.54e-061791397dc6cd46fa652b296ddbc41855f6377946d0a4cdc
ToppCellCOVID-19-Heart-Lymph_EC|Heart / Disease (COVID-19 only), tissue and cell type

HLA-E DOCK5 PIEZO2 EFNA5 KBTBD11 PRKCZ REPS2

1.54e-061791397411620201a860716a8773b92f50f7b94ef34a586
ToppCell3'-Parenchyma_lung-Endothelial-Lymphatic_EC-endothelial_cell_of_lymphatic_vessel-Lymphatic_EC_differentiating-Lymphatic_EC_differentiating_L.2.5.1.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

ADAMTS1 GJC2 DOCK5 PIEZO2 EFNA5 TIE1 KBTBD11

1.66e-061811397e898ecb8d8f2eb2204225b7b0d665cadcd241139
ToppCellfacs-Lung-24m-Endothelial-lymphatic_endothelial-lymphatic_endothelial_cell|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

EMILIN1 HAPLN1 EFNA5 KBTBD11 PRKCZ KCNT1 EPHB1

1.72e-0618213972cc434e46985c66fc36de05344a67aa96d90abc9
ToppCell5'-Adult-LargeIntestine-Mesenchymal-fibroblastic-Stromal_3_(C7+)|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

ADAMTS1 LAMB1 ABCC9 EMILIN1 OLFML3 PIEZO2 MCOLN3

1.72e-0618213973dfa9187e9d2bab1d199079d29209c4648220ada
ToppCellfacs-Lung-24m-Endothelial-lymphatic_endothelial|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

EMILIN1 HAPLN1 EFNA5 KBTBD11 PRKCZ KCNT1 EPHB1

1.72e-0618213970cde2775bdaaa2172499925bd59b0ac2d545eb27
ToppCellfacs-Lung-24m-Endothelial-lymphatic_endothelial-lymphatic_endothelial_cell-lymphatic_endothelial_cell|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

EMILIN1 HAPLN1 EFNA5 KBTBD11 PRKCZ KCNT1 EPHB1

1.72e-0618213973e7457b2a70b45735fb75d6617b7f34cef28758e
ToppCell5'-Parenchyma_lung-Endothelial-Lymphatic_EC-endothelial_cell_of_lymphatic_vessel-Lymphatic_EC_differentiating-Lymphatic_EC_differentiating_L.2.5.1.1|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

GJC2 DOCK5 SLC6A11 PIEZO2 EFNA5 TIE1 KBTBD11

1.78e-0618313974d16bfbadf2cd13008c35e23dd2b5b4ecf92ee11
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic-thymocyte|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GABRB2 ANO5 PKD1L2 NKAIN2 FREM2 PIEZO2 TENM4

1.85e-0618413972cbed6462fea2622871bb7e49b0df3d984239281
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Cortical_Thick_Ascending_Limb_Cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

SLC25A33 CCDC148 EFNA5 TENM4 SLC25A12 CLCN5 MAPK4

1.85e-061841397e8238fe58f94b4f5700ab7f343fb06ea61e899a9
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GABRB2 ANO5 PKD1L2 NKAIN2 FREM2 PIEZO2 TENM4

1.85e-061841397ea7a7e2bac46d4d2c31a5d576b38a032b5335062
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic-proliferating_thymocyte;_DN_to_DP_transition,_dividing_(some_are_Cd8+/_Cd4+,_some_undergoing_VDJ_recombination)|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GABRB2 ANO5 PKD1L2 NKAIN2 FREM2 PIEZO2 TENM4

1.85e-0618413972b19a8c5f823e00812908b23e66bb4e563278aff
ToppCellpdx-Tumor_cells-T5|Tumor_cells / Sample and Cell Type and Tumor Cluster (all cells)

PCSK2 ABCC1 FREM2 CLCN5 RBPMS2 MLLT3 EPHB1

2.06e-0618713977e376831a11ee72ed87abcdac631ca46ae29c250
ToppCellkidney_cells-Hypertensive_with+without-CKD-Endothelial-lymphatic_endothelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

HLA-E GJC2 EMILIN1 DOCK5 PIEZO2 TIE1 EPHB1

2.06e-06187139765d406122dffe18279f14a1ed35ba091730b97be
ToppCellkidney_cells-Hypertensive_with+without-CKD-Endothelial-lymphatic_endothelial_cell-lymphatic_endothelial_cell_of_renal_cortex-lymphatic_endothelial_cell_of_renal_cortex|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

HLA-E GJC2 EMILIN1 DOCK5 PIEZO2 TIE1 EPHB1

2.06e-0618713974c15c0ed41a55271fc793cb76fee97fa64190369
ToppCellkidney_cells-Hypertensive_with+without-CKD-Endothelial-lymphatic_endothelial_cell-lymphatic_endothelial_cell_of_renal_cortex|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

HLA-E GJC2 EMILIN1 DOCK5 PIEZO2 TIE1 EPHB1

2.06e-0618713975274f2b302bbf7fed30c480af4f35058d2cf61e0
ToppCell3'-GW_trimst-2-SmallIntestine-Endothelial-lymphatic_endothelial|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

BCL2L10 HLA-E GJC2 DOCK5 TIE1 KBTBD11 UBR3

2.29e-06190139732400c62cb9de4c2b24af4206c21a0215ab12212
ToppCell3'-GW_trimst-2-SmallIntestine-Endothelial-lymphatic_endothelial-LEC4_(STAB2+)|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

BCL2L10 HLA-E GJC2 DOCK5 TIE1 KBTBD11 UBR3

2.29e-061901397b2bd2cb384bb8a5662064ed1aee68e905e1f780d
ToppCell(5)_Fibroblasts-(5)_Fibroblast-C_(Myofibroblast)|(5)_Fibroblasts / Lung cell shreds - cell class (v4) and cell subclass (v4)

COL6A6 LAMB1 OLFML3 PIEZO2 PLPPR4 CYP7B1 MCOLN3

2.29e-06190139771e112dfb8c3190fe0286b45a046ea789eb6a8db
ToppCell367C-Endothelial_cells-Endothelial-F_(Lymphatics)|Endothelial_cells / Donor, Lineage, Cell class and subclass (all cells)

GJC2 EMILIN1 DOCK5 PIEZO2 EFNA5 KBTBD11 PRKCZ

2.45e-0619213975e709c0714e8eba27e03a6def0544256bedb3ced
ToppCell367C-Endothelial_cells-Endothelial-F_(Lymphatics)-|Endothelial_cells / Donor, Lineage, Cell class and subclass (all cells)

GJC2 EMILIN1 DOCK5 PIEZO2 EFNA5 KBTBD11 PRKCZ

2.45e-0619213975f4f44f15d3a2846981e68296643a4634930a211
ToppCell(5)_Fibroblast-C_(Myofibroblast)|World / Lung cell shreds - cell class (v4) and cell subclass (v4)

COL6A6 LAMB1 EMILIN1 OLFML3 PIEZO2 PLPPR4 CYP7B1

2.62e-06194139729a72e565c19407bbd198cfbc2a78106fe830d05
ToppCellIPF-Endothelial-Lymphatic|Endothelial / Disease state, Lineage and Cell class

EMILIN1 DOCK5 PIEZO2 EFNA5 KBTBD11 ADAMTS15 PRKCZ

2.72e-061951397de88e9d22044b4b3e29676ad02b3e9299cc920ad
ToppCell5'-Parenchyma_lung-Mesenchymal-Fibroblastic-fibroblastic_type_2-Alveolar_fibroblasts|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

COL6A6 ADAMTS1 LAMB1 EMILIN1 OLFML3 PIEZO2 CYP7B1

2.72e-0619513974243190ad291d56694e2155954dbaa879c9d3844
ToppCelldistal-Endothelial-Lymphatic-2|distal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

EMILIN1 LIF PIEZO2 EFNA5 TIE1 KBTBD11 EPHB1

2.72e-061951397f45c1349932ee7eb419cced8a4fdedae3610953f
ToppCelldroplet-Bladder-nan-24m-Endothelial|Bladder / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ADAMTS1 ITGA7 TXNDC11 ADGRL4 TIE1 RBPMS2 CACNA1H

2.81e-0619613979a90dd26e7a43e3fd55e7c5d8354cfa4cdd5a6cc
ToppCellCOVID-19-kidney-TAL|kidney / Disease (COVID-19 only), tissue and cell type

ADAMTS1 CPD CCDC148 EFNA5 TENM4 CLCN5 CACNA1H

2.81e-06196139704f5eb206ed3016a737609a3ebac0c1fcabb94ef
ToppCelldroplet-Bladder-nan-24m-Endothelial-endothelial_cell|Bladder / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ADAMTS1 ITGA7 TXNDC11 ADGRL4 TIE1 RBPMS2 CACNA1H

2.81e-06196139704dfef1bd4ebb0e9469ae80024dc177e469a2560
ToppCellCOPD-Stromal-Myofibroblast|World / Disease state, Lineage and Cell class

COL6A6 ADAMTS1 LAMB1 EMILIN1 OLFML3 PIEZO2 CYP7B1

2.90e-061971397d51f484b4e01ac64233950d0b97fa88825ea1dbb
ToppCell3'-Parenchyma_lung-Mesenchymal-Fibroblastic-fibroblastic_type_2-Alveolar_fibroblasts-Alveolar_fibroblasts_L.2.1.1.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

COL6A6 LAMB1 EMILIN1 OLFML3 PIEZO2 CYP7B1 MCOLN3

2.90e-06197139713896ec65ccda0b928c91d41112dc01b480036b7
ToppCelldroplet-Bladder-nan-24m-Endothelial-endothelial_cell|Bladder / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ADAMTS1 ITGA7 TXNDC11 ADGRL4 TIE1 RBPMS2 CACNA1H

2.90e-061971397488e85991c5e668afb7672942726d9295b8fc7d8
ToppCell367C-Fibroblasts-Fibroblast-C_(Myofibroblast)|367C / Donor, Lineage, Cell class and subclass (all cells)

COL6A6 LAMB1 EMILIN1 OLFML3 PIEZO2 CYP7B1 MCOLN3

3.00e-061981397a9afedbc0556faf4a46f7bf28f4a9adb3bc859d8
ToppCellParenchymal-10x5prime-Stromal-Fibroblastic-Fibro_peribronchial|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

TMEM176A LAMB1 EMILIN1 OLFML3 HAPLN1 FZD1 PLPPR4

3.00e-061981397300d7cc56207d77168390fa1ffcbcf76767b1b80
ToppCellTransplant_Alveoli_and_parenchyma-Endothelial-Lymphatic|Endothelial / Tissue, Lineage and Cell class of Lung Cells from 10X

CYC1 EMILIN1 DOCK5 PIEZO2 EFNA5 KBTBD11 PRKCZ

3.00e-0619813977a99c341736a4a2ac48ef8e2f7951f21a7378946
ToppCell367C-Fibroblasts-Fibroblast-C_(Myofibroblast)-|367C / Donor, Lineage, Cell class and subclass (all cells)

COL6A6 LAMB1 EMILIN1 OLFML3 PIEZO2 CYP7B1 MCOLN3

3.00e-0619813977b5350768f306ec528e271d2ac4470bf668ec6f0
ToppCellproximal-mesenchymal-Alveolar_Fibroblast|proximal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

COL6A6 TMEM176A LAMB1 EMILIN1 OLFML3 PIEZO2 MCOLN3

3.10e-0619913977f4840ae6a888380feca722543e5e52783f3e35d
ToppCellproximal-3-mesenchymal-Alveolar_Fibroblast|3 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

COL6A6 TMEM176A LAMB1 EMILIN1 OLFML3 PIEZO2 MCOLN3

3.10e-061991397301d02bbb37e6f1d24b6e865bc3fe3e91260eb30
ToppCellproximal-mesenchymal-Alveolar_Fibroblast-3|proximal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

COL6A6 TMEM176A LAMB1 EMILIN1 OLFML3 PIEZO2 MCOLN3

3.10e-0619913979a16e519fb0651a7c4d8e05b931df4fb3b0eb3d1
ToppCell(5)_Fibroblast-G|World / Lung cell shreds - cell class (v4) and cell subclass (v4)

COL6A6 ADAMTS1 LAMB1 EMILIN1 OLFML3 PIEZO2 MCOLN3

3.10e-061991397b4a737575be9f8c65771832dd8cd25328d5dae0d
ToppCell356C-Fibroblasts-Fibroblast-J_(Lipofibroblast)|356C / Donor, Lineage, Cell class and subclass (all cells)

COL6A6 ADAMTS1 TMEM176A EMILIN1 OLFML3 CFB CYP7B1

3.10e-061991397675f7c56b03a7918e2d9ca99440df6f27ad8e838
ToppCell356C-Fibroblasts-Fibroblast-J_(Lipofibroblast)-|356C / Donor, Lineage, Cell class and subclass (all cells)

COL6A6 ADAMTS1 TMEM176A EMILIN1 OLFML3 CFB CYP7B1

3.10e-06199139797d74985018816754d11a55b9fb689690ecb1374
ToppCelldistal-mesenchymal-Alveolar_Fibroblast|distal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

COL6A6 TMEM176A EMILIN1 OLFML3 PIEZO2 CYP7B1 MCOLN3

3.10e-061991397655d07cf9a2fd9b945a2ed4f824cba0297de72a8
ToppCellBiopsy_Other_PF-Mesenchymal-Myofibroblasts|Biopsy_Other_PF / Sample group, Lineage and Cell type

COL6A6 LAMB1 EMILIN1 OLFML3 PIEZO2 PLPPR4 CYP7B1

3.21e-062001397e504570fd7eec1524c401b1cfa9d10822d80d994
ToppCelldistal-2-mesenchymal-Alveolar_Fibroblast|2 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

COL6A6 TMEM176A EMILIN1 OLFML3 PIEZO2 CYP7B1 MCOLN3

3.21e-06200139712b705dabec1b3752a488a891eda1a5123fcdc41
ToppCellTracheal-10x5prime-Endothelial-Endothelia_vascular-VE_systemic_arterial|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

ADAMTS1 NKAIN2 ADGRL4 SLC6A3 SLC6A11 TIE1 ADAMTS6

3.21e-0620013975ec31c1be6bcc4124e1489d136570f3de33cc2e9
ToppCellParenchymal-10x5prime-Stromal-Fibroblastic-Fibro_alveolar|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

COL6A6 TMEM176A LAMB1 EMILIN1 OLFML3 PIEZO2 CYP7B1

3.21e-0620013978c62f05c6042f24287a73fbdf80ff4a56f7ff403
ToppCellTracheal-10x5prime-Stromal-Fibroblastic-Fibro_peribronchial|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

COL6A6 LAMB1 EMILIN1 OLFML3 HAPLN1 PLPPR4 CYP7B1

3.21e-0620013978ab0051544ea32eb8b3f7f8ba7582deaf8bf26c0
ToppCellParenchymal-10x5prime-Stromal-Fibroblastic|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

COL6A6 TMEM176A LAMB1 EMILIN1 OLFML3 PIEZO2 CYP7B1

3.21e-0620013976e3d1ae0ef84d3075afa40129a41169996462672
ToppCellBronchial-10x5prime-Stromal-Fibroblastic-Fibro_alveolar|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

COL6A6 TMEM176A LAMB1 EMILIN1 OLFML3 PIEZO2 CYP7B1

3.21e-062001397cb31cfcfa8e6d6cc610c4c22e97bc009dd8a9e7c
ToppCellBiopsy_IPF-Mesenchymal-Myofibroblasts|Biopsy_IPF / Sample group, Lineage and Cell type

COL6A6 LAMB1 EMILIN1 OLFML3 PIEZO2 PLPPR4 CYP7B1

3.21e-062001397c2c6f687c49ba790174b27c7b8b084af30b34c86
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_connecting_tubule_epithelial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

RTN4R LAMB1 CFB EFNA5 NPC1L1 MAPK4

8.35e-061521396eee86b508b8f140ea44e21d8c04c409a7b689e39
ToppCellkidney_cells-Adult_normal_reference-Mesenchymal--glomerular_mesenchymal_cell-Renin-positive_Juxtaglomerular_Granular_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

PCSK2 DUOX2 ITGA7 EMILIN1 ADAMTS6 RBPMS2

1.20e-051621396c7114e24cb5525abb9780ca3d35dbcc4eabd4b64
ToppCellkidney_cells-Adult_normal_reference-Mesenchymal--glomerular_mesenchymal_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

PCSK2 DUOX2 ITGA7 EMILIN1 ADAMTS6 RBPMS2

1.20e-051621396f1851a173d3bcca2981d934161ec85d1cc0af5a2
ToppCellkidney_cells-Adult_normal_reference-Mesenchymal-|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

PCSK2 DUOX2 ITGA7 EMILIN1 ADAMTS6 RBPMS2

1.20e-0516213965d902bb31e691aea9749617cc88303c2448f24b8
ToppCellfacs-Kidney-nan-24m-Epithelial-epithelial_cell_of_proximal_tubule|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SLC6A18 C11orf54 TMEM176A CFB AKR7A2 CRYZ

1.33e-051651396906321cb5f299d77436fb5540fd8c52d7532beca
ToppCellfacs-Kidney-nan-24m-Epithelial-epithelial_cell_of_proximal_tubule|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SLC6A18 C11orf54 TMEM176A CFB AKR7A2 CRYZ

1.33e-05165139602a09d0918b103aca21c36b42c5a8a8ebad8686c
ToppCellPND03-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_airway-ASMC-ASMC_prolif|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

NIPAL4 MYH8 ABCC9 FREM2 RBPMS2 MYBPC3

1.43e-05167139691b14df450bfb6a2b406c88f8c75cd51eeb9e82b
ToppCellPND01-03-samps-Endothelial-Postnatal_endothelial-endothelial_cells_D|PND01-03-samps / Age Group, Lineage, Cell class and subclass

ATP8B1 ADGRL4 PIEZO2 TIE1 PCDH1 EPHB1

1.80e-051741396b4f3f5334803e5903bc496decf923f2e44f7fa3c
ToppCellfacs-Lung-ENDOMUCIN-18m-Endothelial-Lymphatic_endothelial_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NIPAL4 DUOX2 HAPLN1 RIN1 EFNA5 KBTBD11

1.86e-0517513969d082ba0e350162aa6e71b668be074b12a27c7ab
ToppCell5'-Adult-LymphNode-Mesenchymal-Pericytes-Contractile_pericyte_(PLN+)|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

ADAMTS1 ITGA7 PLPPR4 RBPMS2 CACNA1H HACD1

1.86e-051751396294a70786260c9a2b1ba16c88819d786698609e7
ToppCell3'-GW_trimst-1-SmallIntestine-Mesenchymal-mesothelial_cell-Mesothelium_(RGS5+)|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

ATP7B NKAIN2 FREM2 BCO2 MCOLN3 EPHB1

1.86e-051751396f5451c29c487b998778e50349b3d774d5e20fd28
ToppCellfacs-Lung-ENDOMUCIN-18m-Endothelial-endothelial_cell_of_lymphatic_vessel|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NIPAL4 DUOX2 HAPLN1 RIN1 EFNA5 KBTBD11

1.86e-051751396f641f34b52aec5d047430a6f9d026e915da6c11d
ToppCell5'-Adult-LymphNode-Mesenchymal-Pericytes|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

ADAMTS1 ITGA7 PLPPR4 RBPMS2 CACNA1H HACD1

1.86e-051751396798f33bd340261c048b7b45c842b2ccd1ea1fb60
ToppCellfacs-Aorta|facs / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MYH8 IRX3 CFB ADGRL4 HAPLN1 TIE1

1.92e-0517613960b3491451be02c18a16cdb875645be47eb867a7f
ToppCell356C-Fibroblasts-Fibroblast-C_(Myofibroblast)-|356C / Donor, Lineage, Cell class and subclass (all cells)

COL6A6 LAMB1 EMILIN1 OLFML3 PIEZO2 CYP7B1

1.98e-051771396cdfd2f0ee2f692271b1525e414b0f645cdadb1f6
ToppCellfacs-Brain_Non-Myeloid-Cortex_-18m-Neuronal-Granular_Neuron_CB_Gabra6|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RTN4R NPFFR1 TENM4 PLPPR4 SEL1L3 ADAMTS15

1.98e-0517713969b02fd91c110b405eba6cb74ceb90b1286535973
ToppCellfacs-Marrow-B-cells-18m-Hematologic-hematopoietic_stem_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TMEM176A TXNDC11 TG SEL1L3 CACNA1H MCOLN3

1.98e-05177139635d42b07d9c31528bf59199e361bb8a3bfbe3b75
ToppCell356C-Fibroblasts-Fibroblast-C_(Myofibroblast)|356C / Donor, Lineage, Cell class and subclass (all cells)

COL6A6 LAMB1 EMILIN1 OLFML3 PIEZO2 CYP7B1

1.98e-051771396db222faaecbe5600da39277243c4e7e764eb63c9
ToppCell3'-Parenchyma_lung-Endothelial-Lymphatic_EC-endothelial_cell_of_lymphatic_vessel-Lymphatic_EC_differentiating-Lymphatic_EC_differentiating_L.2.5.1.1|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

GJC2 DOCK5 PIEZO2 EFNA5 TIE1 KBTBD11

2.05e-051781396ad3de3e03a401dac64431a541899445262246347
ToppCell3'_v3-bone_marrow-Hematopoietic_Erythro-Mega-Erythrocytic-Meg|bone_marrow / Manually curated celltypes from each tissue

GABRB2 EMILIN1 PIEZO2 RBPMS2 ADAMTS15 HACD1

2.18e-05180139644ba37bead1ac39bce4d3eef00961063c50ced0d
ToppCellPericytes-SSc-ILD_01|World / lung cells shred on cell class, cell subclass, sample id

ITGA7 OLFML3 RBPMS2 CACNA1H KCNT1 EPHB1

2.25e-05181139635c470988a93381eefa300831aabb813fa1b90bd
ToppCell5'-Adult-LymphNode-Mesenchymal-fibroblastic-Transitional_Stromal_3_(C3+)|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

ADAMTS1 CFB LIF TENM4 CYP7B1 CYB5D1

2.25e-051811396ab66a89f316b935d9ba1277426d976b1e9e39757
ToppCellfacs-Liver-Hepatocytes-24m-Epithelial|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ATP7B ATP8B1 ATP9A SLC26A1 PCDH1 ENTPD8

2.32e-051821396770ce9f3f4538d0181a0181543841bc964c68274
DiseaseGoiter

DUOX2 TG CLCN5

3.02e-0671323C0018021
DiseaseAbsence seizure

GABRB3 CACNA1H

1.99e-0521322cv:C0014553
DiseaseYu-Zhi constitution type

GABRB2 FREM2 PIEZO2

3.83e-05151323EFO_0007638
Diseaseattention deficit hyperactivity disorder (implicated_via_orthology)

ADGRL1 ADGRL4 SLC6A3

2.64e-04281323DOID:1094 (implicated_via_orthology)
DiseaseThyroid Dyshormonogenesis 1

DUOX2 TG

2.94e-0461322C1848805
DiseaseEPILEPSY, CHILDHOOD ABSENCE, 1

GABRB3 CACNA1H

2.94e-0461322C1838604
DiseaseIdiopathic generalized epilepsy

GABRB3 CACNA1H

2.94e-0461322cv:C0270850
DiseaseAkinetic Petit Mal

GABRB3 CACNA1H

4.11e-0471322C0001890
DiseaseEpilepsy, Absence, Atypical

GABRB3 CACNA1H

4.11e-0471322C0751124
DiseaseAbsence Seizure Disorder

GABRB3 CACNA1H

4.11e-0471322C4553705
DiseaseJuvenile Absence Epilepsy

GABRB3 CACNA1H

4.11e-0471322C4317339
DiseaseChildhood Absence Epilepsy

GABRB3 CACNA1H

4.11e-0471322C4281785
DiseaseEpilepsy, Minor

GABRB3 CACNA1H

4.11e-0471322C4552765
DiseaseAbsence Epilepsy

GABRB3 CACNA1H

4.11e-0471322C0014553
Diseasechildhood absence epilepsy (is_implicated_in)

GABRB3 CACNA1H

5.46e-0481322DOID:1825 (is_implicated_in)
DiseaseSudden Cardiac Death

PPP1R13L MYBPC3

5.46e-0481322C0085298
DiseaseDistal arthrogryposis

MYH8 PIEZO2

7.00e-0491322cv:C0265213
Disease4-vinylphenol sulfate measurement

GABRB3 EPHB1

8.73e-04101322EFO_0021149
DiseaseDiamond-Blackfan anemia (implicated_via_orthology)

FLVCR1 RPL11

8.73e-04101322DOID:1339 (implicated_via_orthology)
DiseaseDelirium

SLC6A3 LIF

8.73e-04101322C0011206
Diseaseautistic disorder (is_implicated_in)

GABRB2 LAMB1 SLC25A12

8.84e-04421323DOID:12849 (is_implicated_in)
DiseaseFamilial dilated cardiomyopathy

ABCC9 PPCS MYBPC3

1.01e-03441323C0340427
DiseaseLeigh Disease

POLG GFM2 LRPPRC

1.23e-03471323C0023264
Diseaselifestyle measurement, depressive symptom measurement

SLC6A18 ATP8B1 PLPPR4 KBTBD11

1.29e-031051324EFO_0007006, EFO_0010724
DiseaseBipolar Disorder

GABRB2 GABRB3 POLG HLA-E SLC6A3 TENM4 MLLT3 PRKCZ

1.41e-034771328C0005586
Diseaseventricular enlargement measurement

ABCC1 NKAIN2

1.50e-03131322EFO_0010570
DiseaseCongenital Hypothyroidism

DUOX2 TG

1.50e-03131322C0010308
Diseasehypothyroidism (implicated_via_orthology)

DUOX2 TG

1.50e-03131322DOID:1459 (implicated_via_orthology)
Diseasecongenital hypothyroidism (implicated_via_orthology)

DUOX2 TG

1.74e-03141322DOID:0050328 (implicated_via_orthology)
Diseasecognitive function measurement

GABRB2 ATG5 ABCC5 ATP8B1 NKAIN2 ADGRL4 LRPPRC GANAB EFNA5 TENM4 RBPMS2 CACNA1H TMEM131 PCDH1 MYBPC3

1.92e-03143413215EFO_0008354
Diseaseleukemia

PPP1R13L FANCC PRKCZ

1.94e-03551323C0023418
Disease5-oxoproline measurement

CYC1 SHARPIN

2.29e-03161322EFO_0010988
Diseaseretinopathy

TENM4 CYP7B1

2.58e-03171322EFO_0003839
DiseasePsychoses, Substance-Induced

GRM2 SLC6A3

2.58e-03171322C0033941
Diseasevisfatin measurement

GRAMD4 PCDH1

2.58e-03171322EFO_0801230
DiseaseChild Behaviour Checklist assessment

PCSK2 TENM4

2.90e-03181322EFO_0005661
DiseaseCongenital Fiber Type Disproportion

ITGA7 HACD1

2.90e-03181322C0546264
DiseaseSchizophrenia

RTN4R RBM12

2.90e-03181322cv:C0036341
Diseasebreast carcinoma (is_marker_for)

ATP7B BCL2L10 FZD1

3.26e-03661323DOID:3459 (is_marker_for)
DiseasePsychoses, Drug

GRM2 SLC6A3

3.94e-03211322C0033937

Protein segments in the cluster

PeptideGeneStartEntry
QDPGLGLRLIYFSYD

TRBV28

56

A0A5B6
RYAEQIPVTFVLGFY

BEST3

71

Q8N1M1
PAVVVGFSAALGYRY

ADGRL4

541

Q9HBW9
YSQRLGAGDLYPLFA

ADCK1

371

Q86TW2
PYDPGAGLVIFYDFL

CCDC17

391

Q96LX7
RHFGLRFYAYNPLAG

AKR7A2

216

O43488
RFYAYNPLAGGLLTG

AKR7A2

221

O43488
IYQAILDQYPGDLFG

CCDC148

266

Q8NFR7
LDQYPGDLFGRRTLY

CCDC148

271

Q8NFR7
GLRFYAYNPLAGGLL

AKR7L

191

Q8NHP1
LESFGPLGLFYEYLE

ANO5

661

Q75V66
AYLGYPGNRFELVAL

BCL2L10

66

Q9HD36
QPFLQRYYEVLGAAA

BAG6

291

P46379
AFGQNEPILLYIYDF

AHI1

906

Q8N157
VIGFIDFGVVQRYFP

ATP7B

941

P35670
NYFVVRYSLEFGPPD

ADGRL1

386

O94910
RAPLRNKYFFGEGYT

ALKBH5

126

Q6P6C2
SGYAGFILPIEVYFK

MLLT3

76

P42568
FGDGIGRYNIFTYLR

GRM2

446

Q14416
FFPYRLVGLAVGLYA

GRAMD4

351

Q6IC98
PLGVAFYFIQKYFRV

ABCC9

1141

O60706
SLREGLYFNPYFPGQ

CYC1

226

P08574
PAEENGFRYIPFRIY

ATG5

176

Q9H1Y0
GGIEFPQIYYDRFSG

BCO2

461

Q9BYV7
LVAGPDLEYFQRRYF

CYB5D1

6

Q6P9G0
PGLYIVGQRDLLFNY

ATP8B1

1016

O43520
RANGTGYFYVLAPKV

ADAMTS15

621

Q8TE58
RDFLYPAVAPGQVYD

ADAMTS6

471

Q9UKP5
EILDFFYGYQVIPGS

RBM12

871

Q9NTZ6
ELYLLFRPFKGYEGS

RBPMS2

46

Q6ZRY4
ATGPRQYDGIFYEFR

NIPSNAP3A

26

Q9UFN0
GAAIGIPYFTAYRAL

CRYZ

126

Q08257
RGAFYLLGEAYFIQP

ADAMTS1

146

Q9UHI8
YGLGEIFPIENIYSA

EYA3

496

Q99504
GQLVYGGFLYFARRP

OLFML3

211

Q9NRN5
GYFLPRLQGKLGYFL

HIBCH

181

Q6NVY1
FRLAQEGIYTLYPFI

NSUN2

601

Q08J23
DYLDVYVFGVGPLVN

CFB

421

P00751
PIIYGYFNENFRRGF

NPFFR1

326

Q9GZQ6
GPLTRNGFYLAFQDY

EPHB1

166

P54762
YQFGYRKFDGVEGPR

LARP1

361

Q6PKG0
PDGRFLRGYEQFAYD

HLA-E

126

P13747
FLGQLPLYQAGYDAL

HOXA6

21

P31267
VGLLYVGGYERPFAQ

RNGTT

486

O60942
LGVIRYLGFFAKYNL

MCOLN3

386

Q8TDD5
AFLVGQYLLYGFEVR

GJC2

226

Q5T442
VYGYDLGGRFVDFQP

MAPK4

11

P31152
AFDGVYQPPLRGQFY

ENTPD8

336

Q5MY95
ALFILYYTAQGEPFP

LIF

61

P15018
GINPLIDRYFYVSIG

FREM2

1401

Q5SZK8
AGNGLYNFIVPLRAY

KCNT1

791

Q5JUK3
FHIYFLVPAIIYGGD

DUOX2

1246

Q9NRD8
FPRQFIYYLVELLGA

HARBI1

41

Q96MB7
GFPSRILYGDFKQRY

MYH8

711

P13535
AIAYEIFGLVNPFYG

PINK1

441

Q9BXM7
ELIYSIAGGNPYGLF

PCDH1

751

Q08174
LGPLAELFDYGLQQY

PERCC1

171

A0A1W2PR82
QELGPFRGITYFAYL

CSKMT

221

A8MUP2
LFGTIQYRPRYITGY

NKAIN2

51

Q5VXU1
YGRIYGAGQPFAERL

POLG

951

P54098
AGFVRVPEGAYLEFF

LAMB1

586

P07942
GPTEAVGYFLYNLID

LRPPRC

576

P42704
LEYALVNYIFFGRGP

GABRB2

321

P47870
LLEYAFVNYIFFGRG

GABRB3

321

P28472
FASVPLYQGFLIIGY

ATP9A

866

O75110
IPKGFSYLNERGYVA

RICTOR

811

Q6R327
CNGLGPALYGFIFYI

MFSD14A

381

Q96MC6
LSPQDLRFGEGVYYL

PKD1L2

1241

Q7Z442
YFLFLNRYFEVGAPV

NPC1L1

886

Q9UHC9
EAFLAAGYGVLFLYR

PPCS

71

Q9HAB8
PQYQRKGYGRFLIDF

KAT6A

651

Q92794
YGVYIQAAGGPLAFL

ABCC5

846

O15440
LGDLGGYYFRFLPQK

CFAP300

6

Q9BRQ4
YGLMYFGPEELRFSR

FZD1

306

Q9UP38
GYYGQGFPSFLRNKI

DOCK5

1366

Q9H7D0
AYENYLLVFIRGVGP

EPM2AIP1

186

Q7L775
ARYNFFIILYPVGVA

HACD1

201

B0YJ81
GIYDAHIRLNGYPFL

CLCN5

626

P51795
VALFTQGLGYAPIDY

FANCC

131

Q00597
FGDFYRLLVPGTYNL

CPD

416

O75976
EIIEPVYFYIGIVFG

DPY19L4

156

Q7Z388
GAAEYLYFFRVLVPA

EIF3E

146

P60228
GYLPLGFEFAVEITY

FLVCR1

441

Q9Y5Y0
NFRYPPAGVERVFYG

EFHB

296

Q8N7U6
LGFEFRPGREYFYIS

EFNA5

126

P52803
YFIDRDGPLFRYVLN

KCTD6

56

Q8NC69
GLNYSRLLFGIQYPD

CYP7B1

481

O75881
QGVTIFYVDRLGYYP

SPAM1

86

P38567
PYFFERQEELGGAVY

ITGA7

386

Q13683
VVFYGGASLVYRLPQ

CYB561A3

56

Q8NBI2
TVPFDRVLLNDGGYY

EMILIN1

886

Q9Y6C2
GYIRNPYNIFDGIIV

CACNA1H

851

O95180
QEGYVPRNYFGLFPR

PPP1R13L

806

Q8WUF5
AALLYYGPFIVIFQF

MFSD12

126

Q6NUT3
PYIEFGKGFEYRTQL

COL6A6

1346

A6NMZ7
LQGVVFPYFPRLGRY

HAPLN1

156

P10915
FPYFPRLGRYNLNFH

HAPLN1

161

P10915
QGYGAFLPYAAELPI

IRX3

71

P78415
PLGLIYFFVQRFYVA

ABCC1

1121

P33527
GPGLFRGLAALQYLY

RTN4R

146

Q9BZR6
FGLFLYKEQGYHRLP

RIN1

671

Q13671
RYVAGIEGFFGPLKY

SEL1L3

406

Q68CR1
YGLETYLGPLQVAYR

GFM2

551

Q969S9
PDAVTGYYLNRAGFE

TAF10

131

Q12962
ILSAVLGGFFYIRDY

TMEM176A

66

Q96HP8
YAPVAFRYFRELFGI

PIP5K1C

136

O60331
TEGGEPYRLYNLDVF

GANAB

271

Q14697
YGVRQDGDPAFLYLL

SHARPIN

286

Q9H0F6
GFFNIYHPLDPVAYR

SEC23IP

816

Q9Y6Y8
YGLPISRLYARYFQG

PDK3

326

Q15120
VLYNYLFVAGGVAPA

KBTBD11

356

O94819
EEGYLAFYRGLFAQL

SLC25A33

281

Q9BSK2
YGGGAFLIPYVIALV

SLC6A18

51

Q96N87
FLPPYTFQIRVGALY

SNAPC1

66

Q16533
RYEGFFGLYRGLIPQ

SLC25A12

381

O75746
LGYFLPAEFLYRIDQ

C11orf54

291

Q9H0W9
YLGLYAVGNFLPSDE

PLPPR4

321

Q7Z2D5
RYRGPGIFEDLQNYI

TMX4

121

Q9H1E5
GALYIRGLGEFTPLY

SCLY

266

Q96I15
FGIPIERLYVTYFGG

AARS1

126

P49588
VGYFGPTQFYIALKL

REPS2

101

Q8NFH8
YGLDFYVVLGRPGFS

RPL11

126

P62913
PLGYFFVNRASGYLQ

THAP9

336

Q9H5L6
GVRVFRFGGPLYYAN

SLC26A1

536

Q9H2B4
RFGGPLYYANKDFFL

SLC26A1

541

Q9H2B4
VGYGVLTLFGYLRDF

SPTLC2

76

O15270
AIEYAPYGNLLDFLR

TIE1

916

P35590
YKNGGGAFLVPYLLF

SLC6A3

91

Q01959
EIPYQAEVLDGYLGF

TMEM131

421

Q92545
EAVPPNDYYARLFGI

PIEZO2

296

Q9H5I5
GSLYVGDFNYIRRIF

TENM4

1241

Q6N022
YKNGGGAFLIPYVVF

SLC6A11

81

P48066
RQNYGFYIGLGLAFL

NIPAL4

51

Q0D2K0
LDFLSNYEPGVLGYF

TXNDC11

226

Q6PKC3
PRFIFCLIQYLREGY

UBR3

211

Q6ZT12
VAARPGRFFGVYLLY

SLX1A

6

Q9BQ83
GRFFGVYLLYCLNPR

SLX1A

11

Q9BQ83
ADVQFALGLPFYPAY

TG

2626

P01266
NRFPNFLGIIRLYDY

UBQLN3

331

Q9H347
LYYFEFVVDDLPIRG

TM9SF1

126

O15321
VYIDFPGGILSFYGV

TRIM16L

281

Q309B1
NYIAPEILRGEEYGF

PRKCZ

416

Q05513
VPELIIGNGYYFRVF

MYBPC3

1126

Q14896
GVRKLPFAEGLYHFY

PCSK2

56

P16519