Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
DomainIRO

IRX5 IRX3 IRX1 IRX4

1.15e-0861004SM00548
DomainIroquois_homeo

IRX5 IRX3 IRX1 IRX4

1.15e-0861004IPR003893
DomainHomeobox_KN

IRX5 IRX3 IRX1 MEIS1 IRX4

2.34e-08171005PF05920
DomainHomeobox_KN_domain

IRX5 IRX3 IRX1 MEIS1 IRX4

2.34e-08171005IPR008422
DomainHomeobox

IRX5 CERS6 IRX3 IRX1 MEIS1 IRX4 ZFHX4

2.64e-042341007PF00046
DomainHOMEOBOX_1

IRX5 CERS6 IRX3 IRX1 MEIS1 IRX4 ZFHX4

2.78e-042361007PS00027
DomainPAN_AP

MST1 MST1L

2.81e-0451002SM00473
DomainHOX

IRX5 CERS6 IRX3 IRX1 MEIS1 IRX4 ZFHX4

2.85e-042371007SM00389
DomainHOMEOBOX_2

IRX5 CERS6 IRX3 IRX1 MEIS1 IRX4 ZFHX4

3.00e-042391007PS50071
DomainHomeobox_dom

IRX5 CERS6 IRX3 IRX1 MEIS1 IRX4 ZFHX4

3.00e-042391007IPR001356
DomainPAN

MST1 MST1L

5.86e-0471002PS50948
DomainPan_app

MST1 MST1L

5.86e-0471002IPR003609
DomainPAN_1

MST1 MST1L

5.86e-0471002PF00024
Domain-

IRX5 CERS6 IRX3 IRX1 MEIS1 IRX4 ZFHX4

8.21e-0428310071.10.10.60
DomainDUF4599

SPATA31C2 SPATA31C1

1.81e-03121002PF15371
DomainDUF4599

SPATA31C2 SPATA31C1

1.81e-03121002IPR027970
DomainHomeodomain-like

IRX5 CERS6 IRX3 IRX1 MEIS1 IRX4 ZFHX4

2.05e-033321007IPR009057
DomainHomeobox_CS

IRX5 IRX3 IRX1 IRX4 ZFHX4

3.26e-031861005IPR017970
DomainKringle

MST1 MST1L

3.66e-03171002IPR000001
DomainKringle_CS

MST1 MST1L

3.66e-03171002IPR018056
DomainKRINGLE_2

MST1 MST1L

3.66e-03171002PS50070
DomainKringle

MST1 MST1L

3.66e-03171002PF00051
DomainKRINGLE_1

MST1 MST1L

3.66e-03171002PS00021
DomainKR

MST1 MST1L

3.66e-03171002SM00130
Pubmed

Comparison of Iroquois gene expression in limbs/fins of vertebrate embryos.

IRX5 IRX3 IRX1 IRX4

1.22e-096106420408909
Pubmed

Organization of mouse Iroquois homeobox genes in two clusters suggests a conserved regulation and function in vertebrate development.

IRX5 IRX3 IRX1 IRX4

1.22e-096106411042145
Pubmed

Iroquois homeobox 3 regulates odontoblast proliferation and differentiation mediated by Wnt5a expression.

IRX5 IRX3 IRX1 IRX4

1.22e-096106436773339
Pubmed

Regulated expression patterns of IRX-2, an Iroquois-class homeobox gene, in the human breast.

IRX5 IRX3 IRX1 IRX4

1.22e-096106410370142
Pubmed

The prepattern transcription factor Irx3 directs nephron segment identity.

IRX5 IRX3 IRX1 IRX4

2.83e-097106417875669
Pubmed

Sensitive nonradioactive detection of mRNA in tissue sections: novel application of the whole-mount in situ hybridization protocol.

IRX5 IRX3 IRX1 IRX4

5.65e-098106411118473
Pubmed

The Iroquois homeobox gene Irx2 is not essential for normal development of the heart and midbrain-hindbrain boundary in mice.

IRX5 IRX3 IRX1 IRX4

1.01e-089106414585979
Pubmed

Gene and cluster-specific expression of the Iroquois family members during mouse development.

IRX5 IRX3 IRX1 IRX4

1.01e-089106411520674
Pubmed

Patterning the embryonic heart: identification of five mouse Iroquois homeobox genes in the developing heart.

IRX5 IRX3 IRX1 IRX4

2.65e-0811106410926765
Pubmed

The Hematopoietic TALE-Code Shows Normal Activity of IRX1 in Myeloid Progenitors and Reveals Ectopic Expression of IRX3 and IRX5 in Acute Myeloid Leukemia.

IRX5 IRX3 IRX1

2.75e-083106335328612
Pubmed

Iroquois genes influence proximo-distal morphogenesis during rat lung development.

IRX5 IRX3 IRX1

2.74e-075106316299054
Pubmed

Expression of two novel mouse Iroquois homeobox genes during neurogenesis.

IRX5 IRX3 IRX1

2.74e-075106310704856
Pubmed

Expression of Irx6 during mouse morphogenesis.

IRX5 IRX3 IRX4

2.74e-075106311335133
Pubmed

Sequence and evolution of the human T-cell antigen receptor beta-chain genes.

CD8B TRBC2 TRBC1

5.47e-07610633860845
Pubmed

Mst1-FoxO signaling protects Naïve T lymphocytes from cellular oxidative stress in mice.

FOXO1 MST1 MST1L

5.47e-076106319956688
Pubmed

Cardiomyopathy in Irx4-deficient mice is preceded by abnormal ventricular gene expression.

IRX5 IRX3 IRX1 IRX4

1.16e-0626106411238910
Pubmed

Identification of a novel mouse Iroquois homeobox gene, Irx5, and chromosomal localisation of all members of the mouse Iroquois gene family.

IRX5 IRX3 IRX1

1.52e-068106310822268
Pubmed

IRX3 and IRX5 Inhibit Adipogenic Differentiation of Hypertrophic Chondrocytes and Promote Osteogenesis.

IRX5 IRX3

9.20e-062106232662900
Pubmed

Cloning, sequencing, and expression of human macrophage stimulating protein (MSP, MST1) confirms MSP as a member of the family of kringle proteins and locates the MSP gene on chromosome 3.

MST1 MST1L

9.20e-06210628393443
Pubmed

MSP is a negative regulator of inflammation and lipogenesis in ex vivo models of non-alcoholic steatohepatitis.

MST1 MST1L

9.20e-062106227609031
Pubmed

Hepatocyte growth factor-like protein is required for prostate tumor growth in the TRAMP mouse model.

MST1 MST1L

9.20e-062106224980820
Pubmed

Structure of the human D1F15S1A locus: a chromosome 1 locus with 97% identity to the chromosome 3 gene coding for hepatocyte growth factor-like protein.

MST1 MST1L

9.20e-062106210728827
Pubmed

Genetically selected Marchigian Sardinian alcohol-preferring (msP) rats: an animal model to study the neurobiology of alcoholism.

MST1 MST1L

9.20e-062106216961763
Pubmed

Inhibiting endothelial cell Mst1 attenuates acute lung injury in mice.

MST1 MST1L

9.20e-062106239253972
Pubmed

The Iroquois homeobox proteins IRX3 and IRX5 have distinct roles in Wilms tumour development and human nephrogenesis.

IRX5 IRX3

9.20e-062106230246301
Pubmed

Cerebral ischemia-reperfusion is modulated by macrophage-stimulating 1 through the MAPK-ERK signaling pathway.

MST1 MST1L

9.20e-062106232017081
Pubmed

Functional consequences of the macrophage stimulating protein 689C inflammatory bowel disease risk allele.

MST1 MST1L

9.20e-062106224409221
Pubmed

Hepatocyte-specific expression of the mouse hepatocyte growth factor-like protein.

MST1 MST1L

9.20e-06210628340069
Pubmed

Biological effects of targeted inactivation of hepatocyte growth factor-like protein in mice.

MST1 MST1L

9.20e-06210629486989
Pubmed

Structure and function of the PLAA/Ufd3-p97/Cdc48 complex.

PLAA VCP

9.20e-062106219887378
Pubmed

Treatment with XMU-MP-1 erases hyperglycaemic memory in hearts of diabetic mice.

MST1 MST1L

9.20e-062106233887258
Pubmed

HGFL supports mammary tumorigenesis by enhancing tumor cell intrinsic survival and influencing macrophage and T-cell responses.

MST1 MST1L

9.20e-062106225938541
Pubmed

Mst1 regulates post-infarction cardiac injury through the JNK-Drp1-mitochondrial fission pathway.

MST1 MST1L

9.20e-062106229760744
Pubmed

An Armadillo motif in Ufd3 interacts with Cdc48 and is involved in ubiquitin homeostasis and protein degradation.

PLAA VCP

9.20e-062106219805280
Pubmed

Loss of Iroquois homeobox transcription factors 3 and 5 in osteoblasts disrupts cranial mineralization.

IRX5 IRX3

9.20e-062106227453922
Pubmed

Mst1 deletion reduces hyperglycemia-mediated vascular dysfunction via attenuating mitochondrial fission and modulating the JNK signaling pathway.

MST1 MST1L

9.20e-062106231206688
Pubmed

Extensive pleiotropism and allelic heterogeneity mediate metabolic effects of IRX3 and IRX5.

IRX5 IRX3

9.20e-062106234083488
Pubmed

AAA-ATPase p97/Cdc48p, a cytosolic chaperone required for endoplasmic reticulum-associated protein degradation.

IGHM VCP

9.20e-062106211756557
Pubmed

Canonical Wnt/β-catenin activity and differential epigenetic marks direct sexually dimorphic regulation of Irx3 and Irx5 in developing mouse gonads.

IRX5 IRX3

9.20e-062106232108023
Pubmed

VPS13D interacts with VCP/p97 and negatively regulates endoplasmic reticulum-mitochondria interactions.

VPS13D VCP

9.20e-062106234133214
Pubmed

Mst1 inhibition attenuates non-alcoholic fatty liver disease via reversing Parkin-related mitophagy.

MST1 MST1L

9.20e-062106230708325
Pubmed

Melatonin alleviates postinfarction cardiac remodeling and dysfunction by inhibiting Mst1.

MST1 MST1L

9.20e-062106227696525
Pubmed

FOXO1 suppresses PGC-1β gene expression in skeletal muscles.

FOXO1 PPARGC1B

9.20e-062106232433820
Pubmed

Wnt/β-catenin promotes gastric fundus specification in mice and humans.

IRX5 IRX3 IRX1

2.17e-0518106328052057
Pubmed

The Ron/STK receptor tyrosine kinase is essential for peri-implantation development in the mouse.

MST1 MST1L

2.76e-053106210225971
Pubmed

Inhibition of MST1 ameliorates neuronal apoptosis via GSK3β/β-TrCP/NRF2 pathway in spinal cord injury accompanied by diabetes.

MST1 MST1L

2.76e-053106238430683
Pubmed

TRAF2 functions as an activator switch in the reactive oxygen species-induced stimulation of MST1.

MST1 MST1L

2.76e-053106226698664
Pubmed

Inhibition of endogenous Mst1 prevents apoptosis and cardiac dysfunction without affecting cardiac hypertrophy after myocardial infarction.

MST1 MST1L

2.76e-053106217395874
Pubmed

Mst1 participates in the atherosclerosis progression through macrophage autophagy inhibition and macrophage apoptosis enhancement.

MST1 MST1L

2.76e-053106227496379
Pubmed

Receptor tyrosine kinase Ron is expressed in mouse reproductive tissues during embryo implantation and is important in trophoblast cell function.

MST1 MST1L

2.76e-053106212606483
Pubmed

Identification of the vertebrate Iroquois homeobox gene family with overlapping expression during early development of the nervous system.

IRX3 IRX1

2.76e-05310629486539
Pubmed

Mst1-mediated phosphorylation of Nur77 improves the endometrial receptivity in human and mice.

MST1 MST1L

2.76e-053106236623453
Pubmed

CircRbms1 fosters MST1 mRNA and protein levels to motivate myocardial ischaemia-reperfusion injury via autophagic status.

MST1 MST1L

2.76e-053106238288506
Pubmed

The proto-oncogene RON is involved in development of epithelial, bone and neuro-endocrine tissues.

MST1 MST1L

2.76e-05310628545120
Pubmed

Hepatocyte growth factor-like protein is a positive regulator of early mammary gland ductal morphogenesis.

MST1 MST1L

2.76e-053106225049204
Pubmed

Characterization of the mouse cDNA and gene coding for a hepatocyte growth factor-like protein: expression during development.

MST1 MST1L

2.76e-05310621832957
Pubmed

Activation of pro-survival CaMK4β/CREB and pro-death MST1 signaling at early and late times during a mouse model of prion disease.

MST1 MST1L

2.76e-053106225183307
Pubmed

MST1 mediates neuronal loss and cognitive deficits: A novel therapeutic target for Alzheimer's disease.

MST1 MST1L

2.76e-053106235525373
Pubmed

MST1 coordinately regulates autophagy and apoptosis in diabetic cardiomyopathy in mice.

MST1 MST1L

2.76e-053106227510910
Pubmed

Hippo kinases Mst1 and Mst2 maintain NK cell homeostasis by orchestrating metabolic state and transcriptional activity.

MST1 MST1L

2.76e-053106238898027
Pubmed

WASP and Mst1 coregulate B-cell development and B-cell receptor signaling.

MST1 MST1L

2.76e-053106232045478
Pubmed

Impaired liver regeneration in aged mice can be rescued by silencing Hippo core kinases MST1 and MST2.

MST1 MST1L

2.76e-053106227940445
Pubmed

Macrophage stimulating protein is a target-derived neurotrophic factor for developing sensory and sympathetic neurons.

MST1 MST1L

2.76e-053106212538524
Pubmed

Mst1 controls lymphocyte trafficking and interstitial motility within lymph nodes.

MST1 MST1L

2.76e-053106219339990
Pubmed

Melatonin activates Parkin translocation and rescues the impaired mitophagy activity of diabetic cardiomyopathy through Mst1 inhibition.

MST1 MST1L

2.76e-053106230063115
Pubmed

Mst1-mediated phosphorylation of Bcl-xL is required for myocardial reperfusion injury.

MST1 MST1L

2.76e-053106227218122
Pubmed

Genetic deletion of Mst1 alters T cell function and protects against autoimmunity.

MST1 MST1L

2.76e-053106224852423
Pubmed

IRX3 and IRX5 collaborate during ovary development and follicle formation to establish responsive granulosa cells in the adult mouse†.

IRX5 IRX3

2.76e-053106232507881
Pubmed

Macrophage-stimulating protein cooperates with erythropoietin to induce colony formation and MAP kinase activation in primary erythroid progenitor cells.

MST1 MST1L

2.76e-053106212804176
Pubmed

Hippo Kinase MST1-Mediated Cell Metabolism Reprograms the Homeostasis and Differentiation of Granulocyte Progenitor Cells.

MST1 MST1L

2.76e-053106237184367
Pubmed

FTO Obesity Variant Circuitry and Adipocyte Browning in Humans.

IRX5 IRX3

2.76e-053106226287746
Pubmed

Combination of melatonin and irisin ameliorates lipopolysaccharide-induced cardiac dysfunction through suppressing the Mst1-JNK pathways.

MST1 MST1L

2.76e-053106231976559
Pubmed

Over-expressed MST1 impaired spatial memory via disturbing neural oscillation patterns in mice.

MST1 MST1L

2.76e-053106232468668
Pubmed

Nicorandil alleviates myocardial injury and post-infarction cardiac remodeling by inhibiting Mst1.

MST1 MST1L

2.76e-053106229127009
Pubmed

Mst1 Kinase Regulates the Actin-Bundling Protein L-Plastin To Promote T Cell Migration.

MST1 MST1L

2.76e-053106227465533
Pubmed

Suramin protects hepatocytes from LPS-induced apoptosis by regulating mitochondrial stress and inactivating the JNK-Mst1 signaling pathway.

MST1 MST1L

2.76e-053106230771091
Pubmed

MST1 mediates the N-methyl-D-aspartate-induced excitotoxicity in mouse cortical neurons.

MST1 MST1L

2.76e-053106234967918
Pubmed

Embryonic retinoic acid synthesis is essential for heart morphogenesis in the mouse.

IRX5 IRX3 IRX4

3.02e-0520106311245568
Pubmed

Inhibition of TLR4-induced IκB kinase activity by the RON receptor tyrosine kinase and its ligand, macrophage-stimulating protein.

MST1 MST1L

5.50e-054106221078906
Pubmed

Hyperglycemia-Induced Overexpression of PH Domain Leucine-Rich Repeat Protein Phosphatase 1 (PHLPP1) Compromises the Cardioprotective Effect of Ischemic Postconditioning Via Modulation of the Akt/Mst1 Pathway Signaling.

MST1 MST1L

5.50e-054106235715527
Pubmed

Rab13 acts downstream of the kinase Mst1 to deliver the integrin LFA-1 to the cell surface for lymphocyte trafficking.

MST1 MST1L

5.50e-054106225074980
Pubmed

MST1 deficiency promotes B cell responses by CD4+ T cell-derived IL-4, resulting in hypergammaglobulinemia.

MST1 MST1L

5.50e-054106228527887
Pubmed

Mst1 directs Myosin IIa partitioning of low and higher affinity integrins during T cell migration.

MST1 MST1L

5.50e-054106225133611
Pubmed

The Mst1 and Mst2 kinases control activation of rho family GTPases and thymic egress of mature thymocytes.

MST1 MST1L

5.50e-054106222412158
Pubmed

Mst1 regulates hepatic lipid metabolism by inhibiting Sirt1 ubiquitination in mice.

MST1 MST1L

5.50e-054106226903296
Pubmed

Glyceraldehyde-3-phosphate dehydrogenase interacts with proapoptotic kinase mst1 to promote cardiomyocyte apoptosis.

MST1 MST1L

5.50e-054106223527007
Pubmed

MST1 functions as a key modulator of neurodegeneration in a mouse model of ALS.

MST1 MST1L

5.50e-054106223818595
Pubmed

Mammalian sterile 20-like kinase 1 suppresses lymphoma development by promoting faithful chromosome segregation.

MST1 MST1L

5.50e-054106222926556
Pubmed

Identification of components of the murine histone deacetylase 6 complex: link between acetylation and ubiquitination signaling pathways.

PLAA VCP

5.50e-054106211689694
Pubmed

Mst1/2 Kinases Modulate Glucose Uptake for Osteoblast Differentiation and Bone Formation.

MST1 MST1L

5.50e-054106229474739
Pubmed

mTORC2 regulates cardiac response to stress by inhibiting MST1.

MST1 MST1L

5.50e-054106225843706
Pubmed

Thioredoxin-1 functions as a molecular switch regulating the oxidative stress-induced activation of MST1.

MST1 MST1L

5.50e-054106223085515
Pubmed

Distinct steps in dislocation of luminal endoplasmic reticulum-associated degradation substrates: roles of endoplamic reticulum-bound p97/Cdc48p and proteasome.

IGHM VCP

5.50e-054106214607830
Pubmed

MST1 controls murine neutrophil homeostasis via the G-CSFR/STAT3 axis.

MST1 MST1L

5.50e-054106236618429
Pubmed

OSM mitigates post-infarction cardiac remodeling and dysfunction by up-regulating autophagy through Mst1 suppression.

MST1 MST1L

5.50e-054106227825852
Pubmed

LncRNA SNHG17 knockdown promotes Parkin-dependent mitophagy and reduces apoptosis of podocytes through Mst1.

MST1 MST1L

5.50e-054106232627655
Pubmed

Macrophage MST1/2 Disruption Impairs Post-Infarction Cardiac Repair via LTB4.

MST1 MST1L

5.50e-054106234515499
Pubmed

Functional role of Mst1/Mst2 in embryonic stem cell differentiation.

MST1 MST1L

5.50e-054106224224013
Pubmed

A cell-intrinsic role for Mst1 in regulating thymocyte egress.

MST1 MST1L

5.50e-054106219692642
Pubmed

Melatonin protects against diabetic cardiomyopathy through Mst1/Sirt3 signaling.

MST1 MST1L

5.50e-054106228480597
Cytoband5p15.3

IRX1 IRX4

2.39e-041010725p15.3
GeneFamilyTALE class homeoboxes and pseudogenes

IRX5 IRX3 IRX1 MEIS1 IRX4

3.44e-0826665526
CoexpressionGSE2770_TGFB_AND_IL4_VS_IL12_TREATED_ACT_CD4_TCELL_2H_DN

ALDH8A1 RABAC1 EXOC3-AS1 RASAL3 TIMP1 TMED9 GNAS

1.49e-051971057M6075
CoexpressionGSE40274_FOXP3_VS_FOXP3_AND_PBX1_TRANSDUCED_ACTIVATED_CD4_TCELL_UP

PPP4R1 NHSL2 ATP10D MST1 KCNQ5 IGHM KBTBD11

1.64e-052001057M9181
ToppCell367C-Lymphocytic-CD8+_Cytotoxic_T-cell-CD8+_Cytotoxic_T_cell_0|367C / Donor, Lineage, Cell class and subclass (all cells)

APOBEC3D LPAR5 MMP25 CD8B MAP3K9 TRBC2 TRBC1

1.12e-071581077c08b5e12cc2975e52965e22ec987d0d45a9a68e9
ToppCell3'_v3-GI_small-bowel-Lymphocytic_Invariant-Inducer-like-ILC3|GI_small-bowel / Manually curated celltypes from each tissue

SHANK1 CERS6 MEIS1 IRX4 MMP25 KBTBD11

3.06e-061661076773673a5d0430640439845b264740bfbbdad0cb2
ToppCell3'_v3-GI_small-bowel-Lymphocytic_Invariant-Inducer-like|GI_small-bowel / Manually curated celltypes from each tissue

SHANK1 CERS6 MEIS1 IRX4 MMP25 KBTBD11

3.17e-0616710763ae46c6363da76c8e1f5579e6027bf88ed637a44
ToppCellE18.5-samps-Mesenchymal-Pericyte|E18.5-samps / Age Group, Lineage, Cell class and subclass

VTN MINK1 KCNQ5 AOC3 RFLNA GNAS

4.88e-0618010760b1d370db64862fe1c7ea0ffaf06d03ec82e6e70
ToppCellcellseq-Mesenchymal-Fibroblastic-Fibroblastic_1-Mesothelial|cellseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

SHANK1 VTN MST1 ZFHX4 TIMP1 RFLNA

5.89e-0618610767812ed80d2378aca9957ef22fc3c8fb7fb58434b
ToppCellPCW_10-12-Epithelial-Epithelial_alveolar-distal-epi_SOX9^high_Etv5^high_distal_(10)|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung

IRX5 ARHGEF28 IRX3 HID1 IRX1 MAP3K9

6.07e-061871076db2974e2e87ac9f1c2407a371d5ed89af09fc9b7
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Immune-Lymphocytic_T/NK|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

TMC6 CD8B RASAL3 KCNQ5 TRBC2 TRBC1

7.06e-061921076b498618505bb1b7ff9574d06875dd272c11bac39
ToppCell5'-GW_trimst-2-SmallIntestine-Endothelial-lymphatic_endothelial-LEC4_(STAB2+)|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

RELN MYCT1 IRX3 HID1 KBTBD11 GNAS

7.06e-0619210765388f3115ab285f3f3001af1d71543ed64b9e044
ToppCellPCW_07-8.5-Epithelial-Epithelial_alveolar-distal|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

IRX5 ARHGEF28 IRX3 HID1 IRX1 MAP3K9

7.06e-061921076b7c01e12b3e9be960a741b08835f1dfff65d0d47
ToppCellPCW_07-8.5-Epithelial-Epithelial_alveolar-distal-epi_CTGF^high_distal_(3)|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

IRX5 ARHGEF28 IRX3 HID1 IRX1 MAP3K9

7.27e-061931076ab78fb1603ea6f720ba2d30148fe65dccf271fe1
ToppCell5'-GW_trimst-2-SmallIntestine-Endothelial-lymphatic_endothelial|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

RELN MYCT1 IRX3 HID1 KBTBD11 GNAS

7.27e-061931076ef007b736da56529ec628fc3df86a335e7ec3f18
ToppCellAdult-Immune-T_lymphocyte-D231|Adult / Lineage, Cell type, age group and donor

FOXO1 CD8B RASAL3 KCNQ5 TRBC2 TRBC1

7.49e-0619410765c1dca33f382f37a7deb23e573578343c3b54986
ToppCellSubstantia_nigra|World / BrainAtlas - Mouse McCarroll V32

IRX5 IRX3 IRX1 ZFHX4 SLC4A9

8.63e-06115107518174b8d57d444fab1e9d2b13d22939c83c958e0
ToppCellLA-10._Endothelium_II|LA / Chamber and Cluster_Paper

DCST1 PTPRM KBTBD11 TSGA10IP PKN3

1.81e-051341075048fa6ccf305d22d9a53db4ab385f39f558010d8
ToppCellFrontal_cortex-Endothelial-ENDOTHELIAL_STALK-Flt1_1-Endothelial_Stalk.Flt1.Gkn3_(Gkn3)|Frontal_cortex / BrainAtlas - Mouse McCarroll V32

MYCT1 IRX3 MMP25 MST1

1.83e-05651074c736a773a1b9cb16b51849a3bf0ccd9aeec7b342
ToppCellFrontal_cortex-Endothelial-ENDOTHELIAL_STALK-Flt1_1-Endothelial_Stalk.Flt1.Gkn3_(Gkn3)-|Frontal_cortex / BrainAtlas - Mouse McCarroll V32

MYCT1 IRX3 MMP25 MST1

1.83e-056510748f7eac868f1605830cc97d9d1676f3ebff47d49b
ToppCellFrontal_cortex-Endothelial-ENDOTHELIAL_STALK-Flt1_1-Endothelial_Stalk.Flt1.Gkn3_(Gkn3)--|Frontal_cortex / BrainAtlas - Mouse McCarroll V32

MYCT1 IRX3 MMP25 MST1

1.83e-05651074350f33bcc5924d7e3c3318391d33a984763fe206
ToppCellPND01-03-samps-Mesenchymal-Pericyte-pericyte_E|PND01-03-samps / Age Group, Lineage, Cell class and subclass

VTN MINK1 KCNQ5 RFLNA TRBC1

1.88e-05135107535928195cf34f055b353562c96f451aef2344d64
ToppCellE18.5-samps-Mesenchymal-Pericyte-pericyte_C|E18.5-samps / Age Group, Lineage, Cell class and subclass

VTN KCNQ5 AOC3 RFLNA CPEB1

3.22e-0515110753f2abaa42876ce7a71d934ff16abe0cab0991a05
ToppCellTCGA-Cervix-Primary_Tumor-Cervical_Carcinoma-Keratinizing_Cervical_Squamous_Cell_Carcinoma-3|TCGA-Cervix / Sample_Type by Project: Shred V9

PPP4R1 LPAR5 ATP10D VPS13D RNF225

3.76e-051561075ffb9249a115ce31f50b99a7a3d40bf48b9d7f2b0
ToppCellsaliva-Severe-critical_progression_d12-22_no-steroids-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD4_c09-GZMK-FOS_l|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)

LPAR5 MYCT1 PAQR4 TRBC2 TRBC1

3.87e-0515710750a552abfd139afc8516c38ca568f9922511dddce
ToppCell356C-Lymphocytic-CD8+_Cytotoxic_T-cell-CD8+_Cytotoxic_T_cell_3|356C / Donor, Lineage, Cell class and subclass (all cells)

CD8B RASAL3 CHSY3 TRBC2 TRBC1

4.11e-0515910752fb1d2ff52920aeb48d048cf29f0cd45f944a73d
ToppCell3'-GW_trimst-1-LargeIntestine-Hematopoietic-B_cells-CLP|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

RASAL3 IGHM TRBC2 TRBC1 TSGA10IP

4.77e-051641075f5cacd7b2329cb0c7c1696eb4d8f89a4bbd9dda1
ToppCellPosterior_cortex-Endothelial-ENDOTHELIAL_STALK-Flt1_1-Endothelial_Stalk.Flt1.Car4_(Car4)-|Posterior_cortex / BrainAtlas - Mouse McCarroll V32

MYCT1 IRX3 MMP25 CD8B

5.04e-05841074f7ce09c6fb2795b7aecabce00cb9830b3c1a7d0e
ToppCellPosterior_cortex-Endothelial-ENDOTHELIAL_STALK-Flt1_1-Endothelial_Stalk.Flt1.Car4_(Car4)|Posterior_cortex / BrainAtlas - Mouse McCarroll V32

MYCT1 IRX3 MMP25 CD8B

5.04e-058410745d5e519a6652029b9f5275c8e648bbb123fd07b9
ToppCellPosterior_cortex-Endothelial-ENDOTHELIAL_STALK-Flt1_1-Endothelial_Stalk.Flt1.Car4_(Car4)--|Posterior_cortex / BrainAtlas - Mouse McCarroll V32

MYCT1 IRX3 MMP25 CD8B

5.04e-058410742b477de422a9f6a8474cba05094577b88236a4f0
ToppCellVE-Treg-exh_CD4|VE / Condition, Cell_class and T cell subcluster

MINK1 TATDN2 ANO8 MMP25 MST1

5.20e-0516710751036ac1ef9440612500137af9d1929672b077e4d
ToppCell3'-GW_trimst-1-LargeIntestine-Hematopoietic-B_cells|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

IRX1 TCL1B RASAL3 IGHM TSGA10IP

5.65e-051701075e319ab46842d028898c09d6d8f056f896edb1558
ToppCellE16.5-samps-Epithelial-Alveolar_epithelial_precursor-Uncommitted_AE_cell|E16.5-samps / Age Group, Lineage, Cell class and subclass

IRX5 CDC20B IRX3 IRX1 MAP3K9

5.65e-0517010755a64e05c263df915085988d881808221e2c0f2e2
ToppCellPND28-Immune-Immune_Lymphocytic_T/NK|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

CD8B RASAL3 IGHM TRBC2 TRBC1

6.31e-05174107576694cd8a1162047a9ee60521ce84201b4378a47
ToppCell3'-GW_trimst-2-SmallIntestine-Endothelial-lymphatic_endothelial-LEC3_(ADGRG3+)|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

RELN DSCAM NHSL2 MYCT1 MAGED4

6.49e-05175107543be63976da5ad0764d24d90919a77ce46068f52
ToppCellPND14-Immune-Immune_Lymphocytic_T/NK-Lymphocytic_T-CD4_T-CD4_T_mature|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

RASAL3 KBTBD11 TRBC2 TRBC1 IL6R

6.49e-051751075f7547eade69aa1d012db963adf59f36a309beae6
ToppCell10x3'2.3-week_14-16-Myeloid_neutrophil-granulo-eo/baso/mast-basophil|week_14-16 / cell types per 3 fetal stages;per 3',per 5'

LPAR5 ATP10D MMP25 CD8B RASAL3

6.66e-051761075581d78811b2d99f38a2c7cc268aeb1cf932379c2
ToppCellPND14-Immune-Immune_Lymphocytic_T/NK-Lymphocytic_T-CD4_T|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

RASAL3 KBTBD11 TRBC2 TRBC1 IL6R

6.84e-0517710750d6167c6a11c7dec0717ae7c8b4c45341585804f
ToppCell3'-Adult-LargeIntestine-Endothelial-lymphatic_endothelial-LEC1_(ACKR4+)|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

RELN MYCT1 IRX3 ZFHX4 TIMP1

6.84e-051771075dfaed388926ce050730492a532824af68bf4feff
ToppCellfacs-Heart-RV-18m-Mesenchymal-valve_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

VTN STEAP4 GRM7 PPARGC1B AOC3

6.84e-0517710757c3d46ebd7e8726be6871aa9763e281fc0ec6ac8
ToppCellPND10-Immune-Immune_Lymphocytic_T/NK-Lymphocytic_T-CD4_T|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

RASAL3 KBTBD11 TRBC2 TRBC1 IL6R

6.84e-05177107513f22e578728be477b097889af483b1e3f3e18bb
ToppCellfacs-Heart-RV-18m-Mesenchymal-valve_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

VTN STEAP4 GRM7 PPARGC1B AOC3

6.84e-051771075e7b1f3092e6b8d0d580f82648035f5ad12be6961
ToppCell10x_3'_v2v3-Non-neoplastic-Myeloid-DC-DC3-B|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

VTN MINK1 CERS6 MMP25 PKN3

6.84e-051771075d34b086a5931d7f1737a504952d51c47693e91a8
ToppCellPND10-Immune-Immune_Lymphocytic_T/NK-Lymphocytic_T-CD8_T-CD8_T_mature|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

CD8B RASAL3 KBTBD11 TRBC2 TRBC1

7.03e-051781075934a2a7b35a23b56e34d4d0ef68c271513ef1fe9
ToppCellPND14-Immune-Immune_Lymphocytic_T/NK-Lymphocytic_T|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

CD8B RASAL3 KBTBD11 TRBC2 TRBC1

7.03e-051781075a8d6aae3c35de6e7d1421cc48e58688adbdf16aa
ToppCelldroplet-Marrow-nan-3m-Hematologic-hematopoietic_precursor_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MYCT1 MEIS1 CD8B RASAL3 KBTBD11

7.03e-0517810758aef208b6351143562c87715bb11628880abce94
ToppCellControl-T/NK-NK|Control / Disease group,lineage and cell class （2021.01.30）

MEIS1 KCNQ5 PWWP3A TRBC2 TRBC1

7.03e-051781075079fd19bdeed86bf985c4083af432432d66ad546
ToppCellPND10-Immune-Immune_Lymphocytic_T/NK-Lymphocytic_T-CD4_T-CD4_T_mature|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

RASAL3 KBTBD11 TRBC2 TRBC1 IL6R

7.22e-0517910758498f94202434b3cb5d84f1a37d3ad191baf664e
ToppCellHealthy_Control-Lymphoid-T-NK|Healthy_Control / Condition, Lineage, Cell class and cell subclass

CD8B RASAL3 CHSY3 TRBC2 TRBC1

7.22e-0517910754cd0bb3a99f85ff599b4b79a6a9ace3e51f8b296
ToppCell3'-GW_trimst-1-SmallIntestine-Hematopoietic-B_cells|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

IRX1 TCL1B RASAL3 IGHM TRBC2

7.41e-051801075cb6b11883f42c8beff07f899036c803d786ac6a3
ToppCellPND10-Immune-Immune_Lymphocytic_T/NK-Lymphocytic_T|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

CD8B RASAL3 KBTBD11 TRBC2 TRBC1

7.61e-05181107561c6e000db7047fda4b4bb5024f3af24577e7d29
ToppCellPND07-Immune-Immune_Lymphocytic_T/NK-Lymphocytic_T|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

CD8B RASAL3 KBTBD11 TRBC2 TRBC1

7.61e-0518110756a32eb83aa39484ca43c91e6b58302d8dea84b7e
ToppCellPND14-Immune-Immune_Lymphocytic_T/NK|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

CD8B RASAL3 IGHM TRBC2 TRBC1

7.61e-0518110755e1b784c6bd445593855751329ead0eecd5e1736
ToppCellPND10-Immune-Immune_Lymphocytic_T/NK-Lymphocytic_T-CD8_T|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

CD8B RASAL3 KBTBD11 TRBC2 TRBC1

7.81e-051821075c7e07570480295e1ad3c5fbbb16b8e4df90c690d
ToppCell5'-Parenchyma_lung-Endothelial-Lymphatic_EC-endothelial_cell_of_lymphatic_vessel-Lymphatic_EC_differentiating-Lymphatic_EC_differentiating_L.2.5.1.0|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

RELN MYCT1 ZFHX4 KBTBD11 CHSY3

7.81e-05182107553c267ee327e116dbd89d5927ed3bdf78d25ee62
ToppCellPND10-Immune-Immune_Lymphocytic_T/NK|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

CD8B RASAL3 IGHM TRBC2 TRBC1

8.01e-051831075f929c4a42855313641008385f4e785e2a1c5a139
ToppCell3'-GW_trimst-1.5-SmallIntestine-Endothelial-lymphatic_endothelial-LEC4_(STAB2+)|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

RELN MYCT1 IRX3 HID1 KBTBD11

8.01e-051831075a90ffd9c50caa65f537a2e441e37655e1b622327
ToppCell3'-GW_trimst-1.5-SmallIntestine-Endothelial-lymphatic_endothelial|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

RELN MYCT1 IRX3 HID1 KBTBD11

8.01e-05183107513ad20ec140ef5b96fdace3369b5befc0f40bb76
ToppCellPND03-Immune-Immune_Lymphocytic_T/NK-Lymphocytic_T|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

CD8B RASAL3 KBTBD11 TRBC2 TRBC1

8.01e-05183107541ae679e7332fcafa9101e62a4a910ebae63e87c
ToppCellControl-Epithelial_alveolar-AT_2|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

IRX5 ARHGEF28 STEAP4 IRX3 IRX1

8.22e-05184107551e129b3fcc2df083eda05a3afe3717218b1e52b
ToppCellPND07-Immune-Immune_Lymphocytic_T/NK|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

CD8B RASAL3 IGHM TRBC2 TRBC1

8.22e-0518410756642958a81f945da5b26e78d8ad1ef3f27cf8ac8
ToppCell3'-Parenchyma_lung-Endothelial-Lymphatic_EC-endothelial_cell_of_lymphatic_vessel-Lymphatic_EC_mature-Lymphatic_EC_mature_L.2.5.3.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

DSCAM MYCT1 TIMP1 KBTBD11 RFLNA

8.22e-0518410751a4297b9d3cc4744bea0408fd5ee7b33ba2a1d78
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive|renal_medulla_nuclei / Celltypes from Cells and Nuclei per compartment and clinical group

FOXO1 CERS6 PRAG1 PDLIM5 IL6R

8.22e-051841075d2bf0135eb56bb410997dccea39c5ede88a0617f
ToppCell368C-Lymphocytic-CD8+_Cytotoxic_T-cell-CD8+_Cytotoxic_T_cell_0|368C / Donor, Lineage, Cell class and subclass (all cells)

PDPR ATP10D MTM1 TRBC2 TRBC1

8.22e-051841075d48807f9da48bdd015a54c606d2e2a311f181396
ToppCellPCW_05-06-Epithelial-Epithelial_alveolar-distal-epi_SOX9^high_Etv5^high_distal_(10)|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung

IRX5 ARHGEF28 IRX3 IRX1 MAP3K9

8.22e-051841075fa4915b0498f3069fd5ef497286445528f75187e
ToppCellControl-Epithelial_alveolar-AT_2-AT2_Progenitor|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

IRX5 ARHGEF28 STEAP4 IRX3 IRX1

8.43e-0518510758ca1374501eca01d8468130b74d50abfd4329fbe
ToppCellkidney_cells-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_ascending_limb_epithelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

IRX5 RABAC1 IRX3 IRX1 MST1L

8.43e-0518510756da9a06e1514d5d5f47359a14637f02539846096
ToppCellkidney_cells-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_ascending_limb_epithelial_cell-Ascending_Thin_Limb_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

IRX5 RABAC1 IRX3 IRX1 MST1L

8.43e-0518510754a188e2566a75d1b4f3c879a8c241c277c4b451c
ToppCelldroplet-Bladder-Unstain-18m-Endothelial-nan|Bladder / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

VTN MYCT1 STEAP4 IRX3 PKN3

8.65e-051861075e3a14f3ccadbf3211822c67b8956ee01f563307a
ToppCell3'-Child04-06-SmallIntestine-Endothelial-lymphatic_endothelial-LEC3_(ADGRG3+)|Child04-06 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

RELN MYCT1 TIMP1 KBTBD11 GNAS

8.65e-05186107530dd4164c101006c8d95922d89652b82dbe4b5ea
ToppCell3'-Child04-06-SmallIntestine-Endothelial-lymphatic_endothelial|Child04-06 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

RELN MYCT1 TIMP1 KBTBD11 GNAS

8.65e-051861075eeacf59a9e6bf1c9fd59b6b13d35e8abae228cf0
ToppCellPCW_13-14-Epithelial-Epithelial_alveolar-distal-epi_SOX9^high_Etv5^high_distal_(10)|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung

IRX5 ARHGEF28 IRX3 IRX1 MAP3K9

8.65e-051861075bb0bfe9a015151be08a6ffc5d82896d0556d76de
ToppCell356C-Endothelial_cells-Endothelial-E-|356C / Donor, Lineage, Cell class and subclass (all cells)

MYCT1 GRM7 PTPRM CHSY3 PKN3

8.65e-0518610752e024097ee361eeb1d855a4edb8ac8cdad35da06
ToppCell356C-Endothelial_cells-Endothelial-E|356C / Donor, Lineage, Cell class and subclass (all cells)

MYCT1 GRM7 PTPRM CHSY3 PKN3

8.65e-051861075c3449e54454009973818fc1101933c6f0168258c
ToppCellPCW_10-12-Epithelial-Epithelial_proliferating-epi_proliferating1_(8)|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung

IRX5 ARHGEF28 IRX3 IRX1 MAP3K9

8.87e-051871075c2940aec30b3c2c113f6a65126dc6f1969cf301e
ToppCell3'_v3-blood-Lymphocytic_T_CD8-Trm/em_CD8|blood / Manually curated celltypes from each tissue

APOBEC3D CD8B RASAL3 TRBC2 TRBC1

9.09e-05188107521730497f95dc271e4cdfaaf1da8b9ac6eec2ded
ToppCellE18.5-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_vascular-Pericyte|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

KCNQ5 AOC3 RFLNA GNAS CPEB1

9.09e-051881075a906c29e3fda22eecfec3e5cac706c417bf2b7a4
ToppCellPCW_07-8.5-Epithelial-Epithelial_alveolar-distal-epi_SFTPC^high_distal_(9)|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

IRX5 ARHGEF28 IRX3 IRX1 MAP3K9

9.32e-0518910755d9da836ce4308b8458bb3be3871a0aca734b6cd
ToppCellE17.5-Mesenchymal-developing_mesenchymal_cell-mesenchymal_myogenic_precursor_(Axin2+)|E17.5 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

VTN KCNQ5 AOC3 RFLNA GNAS

9.32e-05189107526cfe5b7e7f477f225f4e9f25f983f432f01e183
ToppCellASK428-Epithelial-Transformed_epithelium|ASK428 / Donor, Lineage and Cell class of Lung cells from Dropseq

VTN CDC20B MST1 ZFHX4 TIMP1

9.32e-05189107587189275234b5d59484c58acbb14a09903f2b578
ToppCellPCW_07-8.5-Epithelial-Epithelial_airway-epi_proximal_progenitor1_(6)|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

IRX5 ARHGEF28 IRX3 IRX1 KLHL32

9.32e-0518910757659c7bbd58ee959a159294fb8d17317bbcc5681
ToppCellAT2_cells-Cryobiopsy_01|World / lung cells shred on cell class, cell subclass, sample id

IRX5 STEAP4 IRX3 MST1 CFAP221

9.32e-0518910752d32f09efa982ae458568f6b1cd06bb5078d42a3
ToppCellPCW_05-06-Epithelial-Epithelial_proliferating-epi_proliferating2_(13)|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung

IRX5 ARHGEF28 IRX3 HID1 IRX1

9.32e-051891075c8b8f860aaf6c73863cd79941db6b469c830ef06
ToppCellE17.5-Mesenchymal-developing_mesenchymal_cell|E17.5 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

VTN KCNQ5 AOC3 RFLNA GNAS

9.56e-0519010752ab604d35456beba71c25511e0f819000e6642d2
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Immune-Lymphocytic_T/NK-T_Cell-|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

TMC6 CD8B RASAL3 KCNQ5 TRBC2

9.56e-051901075ba61f04fd38efae01f721ba616252d1372ff1002
ToppCellPCW_07-8.5-Epithelial-Epithelial_alveolar-distal-epi_SOX9^high_Etv5^high_distal_(10)|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

IRX5 ARHGEF28 IRX3 IRX1 MAP3K9

9.56e-051901075625c08a0e5227efc46daa512fd579c3938ff76c7
ToppCellE18.5-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_vascular-Pericyte-Pericyte_mature|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

KCNQ5 AOC3 RFLNA GNAS CPEB1

9.56e-051901075951e067d14412db67dc3babcdf61e41717d7b429
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Immune-Lymphocytic_T/NK-T_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

TMC6 CD8B RASAL3 KCNQ5 TRBC2

9.56e-0519010755a37568000dfc33fcbb59b578c1963fb7cf872ec
ToppCellPND10-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_vascular-Pericyte-Pericyte_mature|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

VTN KCNQ5 AOC3 RFLNA CPEB1

9.56e-0519010757fec459cd2ad12c2923a03d098289337c0a4c1d3
ToppCellBac-SEP-Lymphocyte-T_NK-CD8_TEM|Bac-SEP / Disease, Lineage and Cell Type

LIMA1 CD8B RASAL3 TRBC2 TRBC1

9.80e-05191107584e3aaed71bd35d73af475d610d1b7e71df9ce3f
ToppCell3'-Pediatric_IBD-SmallIntestine-Endothelial-lymphatic_endothelial-LEC3_(ADGRG3+)|Pediatric_IBD / Celltypes from developing, pediatric, Crohn's, & adult GI tract

RELN MYCT1 TIMP1 KBTBD11 GNAS

9.80e-051911075361b123c8289015206d5e706ab2c615d9a724179
ToppCell3'-Pediatric_IBD-SmallIntestine-Endothelial-lymphatic_endothelial|Pediatric_IBD / Celltypes from developing, pediatric, Crohn's, & adult GI tract

RELN MYCT1 TIMP1 KBTBD11 GNAS

9.80e-051911075011dc22c488369734749e839d65d52fe46b6a1a4
ToppCellwk_08-11-Epithelial-Proximal_epithelial-GHRL+_NE_precursor|wk_08-11 / Celltypes from embryonic and fetal-stage human lung

IRX5 IRX3 HID1 KLHL32 HEPN1

9.80e-051911075f0a81f621e63e87ff62224b33cf0c71dfac1d6e2
ToppCellControl-Myeloid-Macrophage_Alveolar|Myeloid / Disease state, Lineage and Cell class

LIMA1 ARHGEF28 PRAG1 PTPRM AOC3

9.80e-051911075a7bb8aba9c59c037d995a77928cc7b4d5cbb82b9
ToppCellPCW_07-8.5-Immune_Lymphocytic-Immune_Lymphocytic_B|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

RASAL3 KCNQ5 IGHM TRBC2 TRBC1

9.80e-051911075beb15dcc6df156ab342fc21a60a874c868780ce4
ToppCellPCW_07-8.5-Epithelial-Epithelial_proliferating-epi_proliferating2_(13)|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

IRX5 ARHGEF28 IRX3 IRX1 MAP3K9

1.00e-04192107525378b5e4b0cea8415ff125783511fc25a56fc00
ToppCell10x5'-lymph-node_spleen-Lymphocytic_T_CD4-Tregs|lymph-node_spleen / Manually curated celltypes from each tissue

FOXO1 LIMA1 TRBC2 TRBC1 IL6R

1.00e-04192107504bd6e135733570e877af9460f87379ed0a5c5f8
ToppCellILEUM-inflamed-(7)_Endothelial_cell-(7)_Lymphatics|(7)_Endothelial_cell / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)

RELN CERS6 ZFHX4 KBTBD11 GNAS

1.00e-041921075d43caf42ec744e895137f31ef65a990e250669d2
ToppCellPCW_13-14-Epithelial-Epithelial_proliferating-epi_proliferating1_(8)|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung

IRX5 IRX3 IRX1 CFAP221 MAP3K9

1.00e-0419210758898332387e5d746feb346ce1dabd6b2218fc6e5
ToppCellPCW_07-8.5-Epithelial-Epithelial_proliferating-epi_proliferating1_(8)|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

IRX5 ARHGEF28 IRX3 HID1 IRX1

1.03e-041931075979980369d2dbee9dc4770d72b93037abd7786eb
ToppCellCOVID-19-lung-CD4+_T_cells_metabolically_active|COVID-19 / Disease (COVID-19 only), tissue and cell type

TMC6 CD8B RASAL3 TRBC2 TRBC1

1.03e-041931075326fd2ce2c4b51e5a38f2a7a09f22f8f0e92735a
ToppCellPCW_05-06-Epithelial-Epithelial_proliferating|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung

IRX5 ARHGEF28 IRX3 HID1 IRX1

1.03e-0419310755f0eba7b1440beb891d94a288f7f18a4e13c3a88
ToppCellInfluenza_Severe-CD8+_Tem|World / Disease group and Cell class

LIMA1 CD8B RASAL3 TRBC2 TRBC1

1.03e-041931075fce6138712353fba14eb046e10d54e112372658e
ToppCellPCW_07-8.5-Epithelial-Epithelial_alveolar-distal-epi_SOX9^high_Etv5^medium_distal_(2)|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

IRX5 ARHGEF28 IRX3 HID1 IRX1

1.03e-0419310754b8202fcfe639a73f69a13f48fc3601ade256346
Diseaseevent-related brain oscillation

KANSL3 GNAS

7.21e-0541032EFO_0004358
Diseasebombesin receptor-activated protein C6orf89 measurement

RASAL3 IGHM

1.20e-0451032EFO_0801428
Diseaserenal overload-type gout

SPATA31C2 SPATA31C1

1.79e-0461032EFO_0021525
Diseaseobesity (is_implicated_in)

MKKS PPARGC1B GNAS IL6R

2.96e-04911034DOID:9970 (is_implicated_in)
Diseaseeosinophil cationic protein measurement

SPATA31C2 SPATA31C1

3.33e-0481032EFO_0010913
Diseaselongitudinal alcohol consumption measurement

SPATA31C2 SPATA31C1

4.28e-0491032EFO_0007645
DiseaseCrohn Disease

VTN MST1 SLC22A4

7.19e-04501033C0010346
Diseaseegg allergy measurement, parental genotype effect measurement

SPATA31C2 SPATA31C1

9.18e-04131032EFO_0005939, EFO_0007018
Diseaseintracranial aneurysm (biomarker_via_orthology)

TIMP1 AOC3

9.18e-04131032DOID:10941 (biomarker_via_orthology)
DiseaseMyopia

IRX5 KCNQ5

1.23e-03151032C0027092
Diseasecoronary thrombosis, GM11992

DSCAM GPATCH1

1.40e-03161032EFO_0001124, EFO_1000883
Diseaseamygdala volume change measurement

SPATA31C2 SPATA31C1

1.40e-03161032EFO_0021490
DiseaseLung diseases

IRX5 IRX3 IRX1

2.60e-03781033C0024115
DiseaseDown syndrome (is_marker_for)

RELN TIMP1

2.66e-03221032DOID:14250 (is_marker_for)
Diseasecongenital heart disease (is_implicated_in)

MKKS IRX1

3.17e-03241032DOID:1682 (is_implicated_in)
Diseaseinflammatory bowel disease (implicated_via_orthology)

MST1 MST1L

3.44e-03251032DOID:0050589 (implicated_via_orthology)

Protein segments in the cluster

PeptideGeneStartEntry
NSLQRHLPQSWRSRS

C2orf16

836

Q68DN1
HLPQSWRSRSRTFQA

C2orf16

841

Q68DN1
WRSGPRSAQRRNAVS

GNAS

591

P84996
SDPQFQWSVRRASNL

SLC4A9

291

Q96Q91
WSSRSPQERSRVLNQ

ALDH8A1

61

Q9H2A2
RLPANRRFQITWFVS

APOBEC3D

91

Q96AK3
WTSGLPRQERSTSRQ

CBY3

26

A6NI87
ARQTRQRLSINWSNF

FAM193A

1241

P78312
KSLFQRWSVRRSSSP

ATP10D

626

Q9P241
TRRQRRQNRSSWIDP

ANO8

706

Q9HCE9
PRFSVQGSRVASSLW

AOC3

321

Q16853
AVLWVNRPQRSSRSR

CD300C

201

Q08708
RFRLSTSWRVPFINS

CPXCR1

131

Q8N123
AVQSLQLSPRTRGSW

RASAL3

981

Q86YV0
LTQVSTWFANARRRL

IRX4

186

P78413
TLTQVSTWFANARRR

IRX5

156

P78411
ITRSANLTDQPSWNR

MEIS1

201

O00470
FQGRWSPSFSRVQLS

ARHGEF28

221

Q8N1W1
WSPAVRTLRNITNNA

PAXIP1

331

Q6ZW49
TWRVRSFPQSSQLSQ

MMP25

121

Q9NPA2
SNLSWQSQTRRTPSL

KIDINS220

1346

Q9ULH0
EELNWSFLRSTRRPF

MKKS

506

Q9NPJ1
TWRASQPSLTVRAQL

MAGED4

371

Q96JG8
WTLARPDATQSQRRR

LPAR5

216

Q9H1C0
FNRRQWTSLSLRVTA

LIMA1

6

Q9UHB6
RSRWPAVFTRVSVFV

MST1L

691

Q2TV78
NNALRTLRGSWFRNT

LRRC53

116

A6NM62
VQKSWSFNDRTRFRP

KCNQ5

461

Q9NR82
TLQRWFFLPRRASQE

CANT1

291

Q8WVQ1
AALGTSWTQRRTQPL

EXOC3-AS1

56

Q8N2X6
WTPSTFVSSRQNRAD

GPATCH1

71

Q9BRR8
RQATRIPLNGTWLFT

LDHAL6B

31

Q9BYZ2
VPRWDFQTGRQLRTS

PDPR

446

Q8NCN5
SSSWIINQRTAIRFR

ABCC11

221

Q96J66
LRPVSTSSSWIGNQR

HROB

101

Q8N3J3
RDLQTLFWRSRVTNP

NAGS

466

Q8N159
WRPRTGTTQSRSFRI

PDLIM5

271

Q96HC4
RLPRNVSAWLSTSTN

GGN

606

Q86UU5
TAPSTSARLRAFGWQ

PAQR4

166

Q8N4S7
TISPRTRFRWIQANY

RELN

1736

P78509
AGQPRKSSSSRRNAW

FOXO1

146

Q12778
NITVTAVARNPRWLS

IL6R

221

P08887
ATGFSPRQIQVSWLR

IGHM

136

P01871
NNTRAAWRISTAPLR

DCST1

156

Q5T197
RIYWLRQRQAPSSDS

CD8B

51

P10966
WFRQRRNQEKPSTLT

CERS6

116

Q6ZMG9
DNPSQLIWTSSRSAR

HSD17B7

161

P56937
ALRRREWNTQRASFS

HEPN1

31

Q6WQI6
TLWNSPSRNRSLQLS

MAP7D1

276

Q3KQU3
SPITTRWQQSQTRAL

CDC20B

71

Q86Y33
FPTSRRHRFWQSQLS

KANSL3

286

Q9P2N6
TSRTLENNRRNVWFA

GRM7

351

Q14831
WVLADSNFVRSPSQR

CPEB1

411

Q9BZB8
SSSSWLTRRAIRPEN

EMD

196

P50402
AAWRRQIRQFSRVSP

EME2

291

A4GXA9
ARSRWPAVFTRVSVF

MST1

686

P26927
ANLSSAWRNNSVPLR

SLC22A4

56

Q9H015
PTRSLRTSTWRLAQD

NDUFS4

31

O43181
TPRRWNTQQDSTLER

MAP3K9

971

P80192
PTRTWNRAELAISTF

PTPRM

136

P28827
PFFRTTNWQALLART

PKN3

816

Q6P5Z2
LTQVSTWFANARRRL

IRX3

171

P78415
ILSTRNWPNRAVEFS

FAM149B1

391

Q96BN6
QAVRARPRSNSAWQI

MINK1

691

Q8N4C8
FDPLINNTWLSRSRA

CFAP221

446

Q4G0U5
TARNRYASQWTLNRP

DSCAM

1741

O60469
RKPSRWLQTFLSSSQ

PWWP3A

596

Q2TAK8
SFKFWRAPSRTSQDR

RTTN

1526

Q86VV8
SPSFNNLRRRQWRKT

TSGA10IP

296

Q3SY00
ASLTRPNRRLRWNSF

STARD13

576

Q9Y3M8
SRSRSPQWRRSRSAQ

SRRM2

506

Q9UQ35
SRSAQRWGRSRSPQR

SRRM2

516

Q9UQ35
SRRLSWGSSRRRNNS

TATDN2

66

Q93075
SDPSRWVRQAAFQSL

PPP4R1

301

Q8TF05
VRRSWLAVNQAFPVS

SPATA31C2

596

B4DYI2
SSWRQPVNVFLSSGR

NHSL2

111

Q5HYW2
LTQVSTWFANARRRL

IRX1

171

P78414
RRRASAPISQWSSSR

MYCT1

96

Q8N699
QAWREQRRPSTSSAS

HID1

661

Q8IV36
CSNPSQQVRSRPWSR

PPARGC1B

316

Q86YN6
SVRRSWLAVNQAFPV

SPATA31C1

601

P0DKV0
SWSAVRPLRQARSQL

KBTBD11

391

O94819
PARNRRTSLWAVSLS

TEX51

131

A0A1B0GUA7
WQNEARRRSTLFLST

SHANK1

1246

Q9Y566
RFSRWFSNPSRSGSR

EIF4ENIF1

336

Q9NRA8
SRALAAQRTWARFIP

CHSY3

186

Q70JA7
GPRRQSSLFQWENSR

CHST4

116

Q8NCG5
RFRQTSESTNQRVLW

TMED9

191

Q9BVK6
APWNSLSLAQRRGFT

TIMP1

126

P01033
SWPNILFQASARRAA

ZFHX4

3476

Q86UP3
VATFRSRNRIPVLSW

MTM1

216

Q13496
SRRLSLASPAWVFNA

RNF225

186

M0QZC1
DFRWALSQSNPSALR

VCP

451

P55072
SSRLRVSATFWQNPR

TRBC1

76

P01850
APLGRRRVQSQWAST

TINF2

261

Q9BSI4
LTSSQQWQSLTPRAR

WDR97

51

A6NE52
SLGRPSRWFTASVQL

RFLNA

186

Q6ZTI6
RTTRLWAPDSPNRSF

PLAA

41

Q9Y263
SLPSVSNAVNWREFR

STEAP4

366

Q687X5
SEQRRPRFQAGTWSR

PRAG1

621

Q86YV5
VVRFNPSRREWARAS

TCL1B

36

O95988
AFVRRIPWTAASSQL

SLIRP

21

Q9GZT3
TIRPWSTFVDQQRFS

RABAC1

41

Q9UI14
STTPSNERKLNRAFW

YTHDC2

1311

Q9H6S0
SSRLRVSATFWQNPR

TRBC2

76

A0A5B9
RSSRPLLGNFVRSAW

TMC6

111

Q7Z403
SRRQPRVVSQWSTSA

POMZP3

171

Q6PJE2
QNSRRPSRATWLSLF

VTN

391

P04004
RKPDRRRSTTQTWSF

VPS13D

3701

Q5THJ4
VWQTRRTKPRFQSDT

KLHL32

276

Q96NJ5