Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionbeta-adrenergic receptor kinase activity

GRK5 GRK6

6.83e-054682GO:0047696
GeneOntologyMolecularFunctionG protein-coupled receptor kinase activity

GRK5 GRK6

2.37e-047682GO:0004703
DomainZinc_finger_PHD-type_CS

BPTF ING1 NFXL1 BAZ1B

7.26e-0565644IPR019786
DomainDDT

BPTF BAZ1B

1.15e-045642SM00571
DomainWSD

BPTF BAZ1B

1.15e-045642PF15613
DomainWHIM1

BPTF BAZ1B

1.15e-045642PF15612
DomainDDT_dom

BPTF BAZ1B

1.15e-045642IPR018501
DomainWHIM1_dom

BPTF BAZ1B

1.15e-045642IPR028942
DomainWHIM2_dom

BPTF BAZ1B

1.15e-045642IPR028941
DomainDDT

BPTF BAZ1B

1.72e-046642PS50827
DomainRGS

RGS5 GRK5 GRK6

2.32e-0435643PF00615
DomainRGS

RGS5 GRK5 GRK6

2.32e-0435643SM00315
DomainGPCR_kinase

GRK5 GRK6

2.40e-047642IPR000239
DomainRGS

RGS5 GRK5 GRK6

2.53e-0436643PS50132
DomainRGS

RGS5 GRK5 GRK6

3.21e-0439643IPR016137
DomainZnf_FYVE_PHD

BPTF ING1 SYTL2 BAZ1B

1.62e-03147644IPR011011
DomainPHD

BPTF ING1 BAZ1B

2.17e-0375643PF00628
DomainZnf_PHD-finger

BPTF ING1 BAZ1B

2.52e-0379643IPR019787
DomainPHD

BPTF ING1 BAZ1B

3.53e-0389643SM00249
DomainBromodomain_CS

BPTF BAZ1B

3.56e-0326642IPR018359
DomainZnf_PHD

BPTF ING1 BAZ1B

3.76e-0391643IPR001965
DomainDnaJ_domain_CS

DNAJB1 DNAJC2

3.84e-0327642IPR018253
DomainZF_PHD_2

BPTF ING1 BAZ1B

4.24e-0395643PS50016
DomainZF_PHD_1

BPTF ING1 BAZ1B

4.37e-0396643PS01359
DomainPROTEIN_KINASE_ATP

STK32A TLK1 GRK5 GRK6 STK32B RYK

4.80e-03459646PS00107
DomainbZIP_1

ATF6 CREB3L2

6.04e-0334642PF00170
DomainProt_kinase_dom

STK32A TLK1 GRK5 GRK6 STK32B RYK

6.50e-03489646IPR000719
DomainPROTEIN_KINASE_DOM

STK32A TLK1 GRK5 GRK6 STK32B RYK

6.75e-03493646PS50011
DomainBROMODOMAIN_1

BPTF BAZ1B

7.13e-0337642PS00633
DomainBromodomain

BPTF BAZ1B

7.51e-0338642PF00439
DomainSer/Thr_kinase_AS

STK32A TLK1 GRK5 GRK6 STK32B

7.53e-03357645IPR008271
DomainS_TKc

STK32A TLK1 GRK5 GRK6 STK32B

7.70e-03359645SM00220
DomainPROTEIN_KINASE_ST

STK32A TLK1 GRK5 GRK6 STK32B

7.97e-03362645PS00108
DomainBROMODOMAIN_2

BPTF BAZ1B

8.70e-0341642PS50014
DomainBROMO

BPTF BAZ1B

9.11e-0342642SM00297
DomainBromodomain

BPTF BAZ1B

9.11e-0342642IPR001487
Domain-

BPTF BAZ1B

9.11e-03426421.20.920.10
DomainProtein_kinase_ATP_BS

STK32A TLK1 GRK5 GRK6 STK32B

9.60e-03379645IPR017441
DomainPkinase

STK32A TLK1 GRK5 GRK6 STK32B

9.81e-03381645PF00069
Pubmed

Comprehensive interactome profiling of the human Hsp70 network highlights functional differentiation of J domains.

DNAJB1 ATF6 HSP90B1 TXLNA CCDC88A NAA15 MYO6 EFR3B NFXL1 BAZ1B DNAJC2 MPP7 NOL8 EFR3A

1.09e-061487691433957083
Pubmed

A Degradation Motif in STAU1 Defines a Novel Family of Proteins Involved in Inflammation.

DNAJB1 RBM22 TXLNA MYO6 CNOT10 DDX60 SMC6 NFXL1 SMG5 NOL8

1.62e-06724691036232890
Pubmed

Two-marker association tests yield new disease associations for coronary artery disease and hypertension.

HSP90B1 MYO6 STK32B

2.11e-061369321626137
Pubmed

Beta-arrestin-mediated beta1-adrenergic receptor transactivation of the EGFR confers cardioprotection.

GRK5 GRK6

3.88e-06269217786238
Pubmed

Role for the regulator of G-protein signaling homology domain of G protein-coupled receptor kinases 5 and 6 in beta 2-adrenergic receptor and rhodopsin phosphorylation.

GRK5 GRK6

3.88e-06269220038610
Pubmed

Chromosomal mapping of the genes GPRK5 and GPRK6 encoding G protein-coupled receptor kinases GRK5 and GRK6.

GRK5 GRK6

1.16e-0536927789183
Pubmed

G Protein-coupled receptor kinases phosphorylate LRP6 in the Wnt pathway.

GRK5 GRK6

1.16e-05369219801552
Pubmed

EFR3s are palmitoylated plasma membrane proteins that control responsiveness to G-protein-coupled receptors.

EFR3B EFR3A

1.16e-05369225380825
Pubmed

Defective lymphocyte chemotaxis in beta-arrestin2- and GRK6-deficient mice.

GRK5 GRK6

1.16e-05369212032308
Pubmed

T6BP and NDP52 are myosin VI binding partners with potential roles in cytokine signalling and cell adhesion.

MYO6 TAX1BP1

1.16e-05369217635994
Pubmed

Mechanistic Insights into Recognitions of Ubiquitin and Myosin VI by Autophagy Receptor TAX1BP1.

MYO6 TAX1BP1

1.16e-05369229940186
Pubmed

The Wnt receptor Ryk plays a role in mammalian planar cell polarity signaling.

MYO6 RYK

1.16e-05369222773843
Pubmed

Expression of G-protein-coupled receptor kinases in pregnant term and non-pregnant human myometrium.

GRK5 GRK6

1.16e-05369210467231
Pubmed

Granulocyte chemotaxis and disease expression are differentially regulated by GRK subtype in an acute inflammatory arthritis model (K/BxN).

GRK5 GRK6

1.16e-05369218662895
Pubmed

G-protein receptor kinases 2, 5 and 6 redundantly modulate Smoothened-GATA transcriptional crosstalk in fetal mouse hearts.

GRK5 GRK6

2.32e-05469229969579
Pubmed

Reduced expression of G protein-coupled receptor kinases in schizophrenia but not in schizoaffective disorder.

GRK5 GRK6

2.32e-05469221784156
Pubmed

Phosphorylation and desensitization of the human thromboxane receptor-alpha by G protein-coupled receptor kinases.

GRK5 GRK6

2.32e-05469211504827
Pubmed

Myosin VI-Dependent Actin Cages Encapsulate Parkin-Positive Damaged Mitochondria.

MYO6 TAX1BP1

2.32e-05469229398621
Pubmed

Targeting USP10 induces degradation of oncogenic ANLN in esophageal squamous cell carcinoma.

RBM22 HSP90B1 TXLNA NAA15 DSTN MYO6 DDX60 BAZ1B LANCL2 DNAJC2 NOL8

3.51e-051257691136526897
Pubmed

c-Src, Insulin-Like Growth Factor I Receptor, G-Protein-Coupled Receptor Kinases and Focal Adhesion Kinase are Enriched Into Prostate Cancer Cell Exosomes.

GRK5 GRK6

3.86e-05569227232975
Pubmed

Aberrantly expressed recoverin is functionally associated with G-protein-coupled receptor kinases in cancer cell lines.

GRK5 GRK6

3.86e-05569212507501
Pubmed

The leukodystrophy protein FAM126A (hyccin) regulates PtdIns(4)P synthesis at the plasma membrane.

EFR3B EFR3A

3.86e-05569226571211
Pubmed

A human MAP kinase interactome.

PROM1 ATF6 HSP90B1 TLK1 CCDC88A MYO6 MYNN

5.09e-0548669720936779
Pubmed

Tagging genes with cassette-exchange sites.

BPTF TLK1 ZFP42 NAA15 BAZ1B SMG5

5.50e-0533569615741177
Pubmed

beta2-Adrenergic receptor regulation by GIT1, a G protein-coupled receptor kinase-associated ADP ribosylation factor GTPase-activating protein.

GRK5 GRK6

5.79e-0566929826657
Pubmed

Phosphorylation and desensitization of human endothelin A and B receptors. Evidence for G protein-coupled receptor kinase specificity.

GRK5 GRK6

5.79e-0566929211925
Pubmed

Structure of Myosin VI/Tom1 complex reveals a cargo recognition mode of Myosin VI for tethering.

MYO6 TAX1BP1

5.79e-05669231371777
Pubmed

Myosin VI Contains a Compact Structural Motif that Binds to Ubiquitin Chains.

MYO6 TAX1BP1

5.79e-05669226971995
Pubmed

β-arrestin-biased agonism of β-adrenergic receptor regulates Dicer-mediated microRNA maturation to promote cardioprotective signaling.

GRK5 GRK6

5.79e-05669229627294
Pubmed

beta-Arrestin-biased agonism of the angiotensin receptor induced by mechanical stress.

GRK5 GRK6

5.79e-05669220530803
Pubmed

Combinatorial depletions of G-protein coupled receptor kinases in immune cells identify pleiotropic and cell type-specific functions.

GRK5 GRK6

5.79e-05669236451830
Pubmed

The GRK4 subfamily of G protein-coupled receptor kinases. Alternative splicing, gene organization, and sequence conservation.

GRK5 GRK6

5.79e-05669210506199
Pubmed

Beta-arrestin2-mediated inotropic effects of the angiotensin II type 1A receptor in isolated cardiac myocytes.

GRK5 GRK6

5.79e-05669217060617
Pubmed

BioID-based intact cell interactome of the Kv1.3 potassium channel identifies a Kv1.3-STAT3-p53 cellular signaling pathway.

DNAJB1 HSP90B1 CCDC88A MYO6 EFR3B LANCL2 MPP7 EFR3A

7.94e-0570869839231216
Pubmed

A potent modifier of liver cancer risk on distal mouse chromosome 1: linkage analysis and characterization of congenic lines.

ATF6 RGS5

8.09e-05769215238534
Pubmed

Members of the G protein-coupled receptor kinase family that phosphorylate the beta2-adrenergic receptor facilitate sequestration.

GRK5 GRK6

8.09e-0576928672451
Pubmed

PtdIns4P synthesis by PI4KIIIα at the plasma membrane and its impact on plasma membrane identity.

EFR3B EFR3A

8.09e-05769223229899
Pubmed

Determination of bradykinin B2 receptor in vivo phosphorylation sites and their role in receptor function.

GRK5 GRK6

8.09e-05769211517230
Pubmed

Prediction of the coding sequences of mouse homologues of KIAA gene: III. the complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.

CCDC88A SETBP1 SANBR EFR3B SMG5 ANKH EFR3A

8.65e-0552969714621295
Pubmed

hsp70-DnaJ chaperone pair prevents nitric oxide- and CHOP-induced apoptosis by inhibiting translocation of Bax to mitochondria.

DNAJB1 ATF6

1.08e-04869214752510
Pubmed

In-Depth In Vivo Crosslinking in Minutes by a Compact, Membrane-Permeable, and Alkynyl-Enrichable Crosslinker.

BPTF RBM22 HSP90B1 TLK1 GRK5 GRK6 SANBR NFXL1 GRIA2 MYNN PEX11A

1.20e-041442691135575683
Pubmed

FOXA1 Directs H3K4 Monomethylation at Enhancers via Recruitment of the Methyltransferase MLL3.

DNAJB1 ZFP42 DSTN DEUP1 NOL8

1.37e-0424869527926873
Pubmed

Toll-like receptors differentially regulate GPCR kinases and arrestins in primary macrophages.

GRK5 GRK6

1.38e-04969218180038
Pubmed

The Autophagy Receptor TAX1BP1 and the Molecular Motor Myosin VI Are Required for Clearance of Salmonella Typhimurium by Autophagy.

MYO6 TAX1BP1

1.38e-04969226451915
Pubmed

Developmental heterogeneity of embryonic neuroendocrine chromaffin cells and their maturation dynamics.

RGS5 LRP1B

1.38e-04969236237181
Pubmed

The RNA-mediated estrogen receptor α interactome of hormone-dependent human breast cancer cell nuclei.

DNAJB1 RBM22 CNOT10 MKRN1 BAZ1B UTRN DNAJC2 MPP7 HMG20B NOL8 EFR3A

1.66e-041497691131527615
Pubmed

Synucleins are a novel class of substrates for G protein-coupled receptor kinases.

GRK5 GRK6

1.73e-041069210852916
Pubmed

Identification of Novel CK2 Kinase Substrates Using a Versatile Biochemical Approach.

HSP90B1 NAA15

1.73e-041069230855574
Pubmed

RNF43 inhibits WNT5A-driven signaling and suppresses melanoma invasion and resistance to the targeted therapy.

HSP90B1 CCDC88A MYO6 EFR3B UTRN

1.80e-0426369534702444
Pubmed

Endoplasmic reticulum stress during the embryonic development of the central nervous system in the mouse.

ATF6 HSP90B1

2.11e-041169217913437
Pubmed

Cochlear hair cell innervation is dependent on a modulatory function of Semaphorin-3A.

MYO6 GRIA2

3.48e-041469236284453
Pubmed

ZW10 links mitotic checkpoint signaling to the structural kinetochore.

SMG5 KNL1

3.48e-041469215824131
Pubmed

Normal development and fertility of knockout mice lacking the tumor suppressor gene LRP1b suggest functional compensation by LRP1.

HSP90B1 LRP1B

3.48e-041469215082773
Pubmed

From the Cover: Indispensability of the glutamate transporters GLAST and GLT1 to brain development.

NAA15 GRIA2

3.48e-041469216880397
Pubmed

Adaptation to ER stress is mediated by differential stabilities of pro-survival and pro-apoptotic mRNAs and proteins.

ATF6 HSP90B1

4.01e-041569217090218
Pubmed

ATG5 is required for B cell polarization and presentation of particulate antigens.

DNAJB1 HSP90B1 TXLNA GRK5 LANCL2 DNAJC2 EFR3A

4.79e-0470169730196744
Pubmed

N-Terminal Acetyltransferase Naa40p Whereabouts Put into N-Terminal Proteoform Perspective.

DNAJB1 HSP90B1 NAA15 MYO6 BAZ1B UTRN KNL1 NOL8

5.16e-0493469833916271
Pubmed

A genome-wide RNAi screen identifies multiple synthetic lethal interactions with the Ras oncogene.

PROM1 NAA15 SYTL2 KNL1 NOL8

5.17e-0433169519490893
Pubmed

A Rich1/Amot complex regulates the Cdc42 GTPase and apical-polarity proteins in epithelial cells.

SH3KBP1 MPP7

5.18e-041769216678097
Pubmed

Motor protein-dependent transport of AMPA receptors into spines during long-term potentiation.

MYO6 GRIA2

5.81e-041869218311135
Pubmed

Genome-wide analysis of BMI in adolescents and young adults reveals additional insight into the effects of genetic loci over the life course.

SEC16B EFR3B

5.81e-041869223669352
Pubmed

Hrd1-mediated ACLY ubiquitination alleviate NAFLD in db/db mice.

HSP90B1 MYO6

6.49e-041969232888949
Pubmed

MYC multimers shield stalled replication forks from RNA polymerase.

DNAJB1 BPTF RBM22 HSP90B1 BAZ1B RYK KNL1 NOL8

7.50e-0498969836424410
Pubmed

Voltage-dependent conformational changes of Kv1.3 channels activate cell proliferation.

HSP90B1 DDX60 SYTL2 TRPM1

7.93e-0420869433230847
Pubmed

Promyelocytic leukemia protein interacts with the apoptosis-associated speck-like protein to limit inflammasome activation.

NAA15 PSTPIP1

7.95e-042169224407287
Pubmed

Mammalian HSP40/DNAJ homologs: cloning of novel cDNAs and a proposal for their classification and nomenclature.

DNAJB1 DNAJC2

8.73e-042269211147971
Pubmed

E-cadherin interactome complexity and robustness resolved by quantitative proteomics.

DNAJB1 MYO6 SH3KBP1 UTRN MPP7 EFR3A

9.03e-0456569625468996
Pubmed

Cooperative polarization of MCAM/CD146 and ERM family proteins in melanoma.

CCDC88A MYO6 EFR3B UTRN EFR3A

9.28e-0437769538117590
Pubmed

CDNF and MANF regulate ER stress in a tissue-specific manner.

ATF6 HSP90B1

1.04e-032469235129674
Pubmed

Mouse Fem1b interacts with the Nkx3.1 homeoprotein and is required for proper male secondary sexual development.

HSP90B1 HMG20B

1.04e-032469218816836
Pubmed

Prediction of the coding sequences of unidentified human genes. XVIII. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro.

SYTL2 ANKH KNL1

1.08e-0310169310997877
Pubmed

Phenotypic and Interaction Profiling of the Human Phosphatases Identifies Diverse Mitotic Regulators.

DNAJB1 HSP90B1 CCDC88A EFR3B UTRN MPP7 KNL1 EFR3A

1.10e-03104969827880917
Pubmed

Resolution of cell fate decisions revealed by single-cell gene expression analysis from zygote to blastocyst.

BPTF ING1 MKRN1 BAZ1B MYNN HMG20B CREB3L2

1.10e-0380869720412781
Pubmed

Interactome and Proteome Dynamics Uncover Immune Modulatory Associations of the Pathogen Sensing Factor cGAS.

TXLNA DDX60 TAX1BP1 BAZ1B

1.11e-0322869430471916
Pubmed

Functional proteomics mapping of a human signaling pathway.

DSTN MYO6 TAX1BP1 SYTL2 UTRN KNL1

1.14e-0359169615231748
Pubmed

MicroRNAs and target site screening reveals a pre-microRNA-30e variant associated with schizophrenia.

GRIA2 UTRN

1.32e-032769220347265
Pubmed

Recruitment of the Mammalian Histone-modifying EMSY Complex to Target Genes Is Regulated by ZNF131.

RBM22 TXLNA ING1

1.39e-0311069326841866
Pubmed

The protein kinase complement of the human genome.

STK32A STK32B

1.42e-032869212471243
Pubmed

Endoplasmic reticulum resident protein 44 (ERp44) deficiency in mice and zebrafish leads to cardiac developmental and functional defects.

ATF6 HSP90B1

1.42e-032869225332179
Pubmed

PRISMA and BioID disclose a motifs-based interactome of the intrinsically disordered transcription factor C/EBPα.

DNAJB1 BPTF RBM22 TLK1 TXLNA NAA15 KNL1 HMG20B

1.51e-03110369834189442
Pubmed

Proteomic analyses reveal distinct chromatin-associated and soluble transcription factor complexes.

BPTF ATF6 RBM22 ING1 NFXL1 SMG5 HMG20B

1.54e-0385769725609649
Pubmed

A chromatin modulator sustains self-renewal and enables differentiation of postnatal neural stem and progenitor cells.

PLA2G7 PROM1

1.63e-033069231065682
Pubmed

The PHLPP1 N-Terminal Extension Is a Mitotic Cdk1 Substrate and Controls an Interactome Switch.

CCDC88A MPP7 KNL1 EFR3A

1.70e-0325669433397691
Pubmed

The unfolded protein response: integrating stress signals through the stress sensor IRE1α.

ATF6 HSP90B1

1.74e-033169222013210
Pubmed

Proximity biotinylation and affinity purification are complementary approaches for the interactome mapping of chromatin-associated protein complexes.

DNAJB1 TXLNA CNOT10 TAX1BP1 SMC6 UTRN

1.77e-0364569625281560
Pubmed

Association of mitotic regulation pathway polymorphisms with pancreatic cancer risk and outcome.

SMC6 RYK

1.85e-033269220056645
InteractionLRRC63 interactions

LRRC63 HSP90B1

1.02e-052652int:LRRC63
InteractionLCK interactions

CCDC88A DSTN MYO6 CNOT10 SH3KBP1 EFR3B UTRN MPP7 EFR3A

1.69e-05463659int:LCK
GeneFamilyPHD finger proteins

BPTF ING1 BAZ1B

8.87e-049038388
GeneFamilyBasic leucine zipper proteins

ATF6 CREB3L2

4.75e-0349382506
GeneFamilyDNAJ (HSP40) heat shock proteins|C2 tensin-type domain containing

DNAJB1 DNAJC2

4.75e-0349382584
CoexpressionDING_LUNG_CANCER_EXPRESSION_BY_COPY_NUMBER

ING1 GOLGA7 MYNN RYK DNAJC2

5.85e-06100675M14670
CoexpressionHAMAI_APOPTOSIS_VIA_TRAIL_UP

BPTF HSP90B1 CCDC88A NAA15 MYO6 TAX1BP1 SMC6 BAZ1B TRPM1 KNL1

6.18e-066566710M18979
CoexpressionBAELDE_DIABETIC_NEPHROPATHY_DN

HSP90B1 TLK1 DSTN ING1 GRK5 TAX1BP1 CREB3L2 EFR3A

1.55e-05437678M4665
CoexpressionAtlasFacebaseRNAseq_e10.5_Neural Epithelium Flanking Eminence_top-relative-expression-ranked_2500_k-means-cluster#5

PROM1 CCDC88A SETBP1 SH3KBP1 SMC6 SANBR BAZ1B MYNN DNAJC2 MPP7 KNL1 NOL8

7.11e-068316512Facebase_RNAseq_e10.5_Neural Epithelium Flanking Eminence_2500_K5
CoexpressionAtlasFacebaseRNAseq_e10.5_Neural Epithelium Flanking Eminence_top-relative-expression-ranked_500_k-means-cluster#3

PROM1 SMC6 SANBR DNAJC2 KNL1 NOL8

2.68e-05192656Facebase_RNAseq_e10.5_Neural Epithelium Flanking Eminence_500_K3
ToppCell(11)_FOXN4+-(2)_GFP_FOXI1|(11)_FOXN4+ / shred by cell type by condition

BPTF TLK1 CCDC88A NAA15 TAX1BP1 UTRN

5.87e-0719868676d40b8c2f8399725b3a62ee2ae0896559cf91eb
ToppCellTCGA-Bone_and_Soft_Tissue-Primary_Tumor-Sarcoma-Undifferentiated_Pleomorphic_Sarcoma-4|TCGA-Bone_and_Soft_Tissue / Sample_Type by Project: Shred V9

DNAJB1 GRK5 TAX1BP1 STK32B DNAH17

1.74e-061316852ccf679b5035b7b9cdb9a9a660cad90288592187
ToppCell356C-Myeloid-Macrophage-SPP1+_Macrophage_2|Myeloid / Donor, Lineage, Cell class and subclass (all cells)

PLA2G7 C10orf67 STK32B ANKH FILIP1L

3.28e-06149685a6c24d8f3b5f08587f0a12cd63d166b68ea000c7
ToppCelldroplet-Marrow-nan-3m|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CCDC88A SH3KBP1 BAZ1B UTRN FILIP1L

9.17e-061846851154a5ad7b8512272b7476f949ddac350910bfb7
ToppCellfacs-Pancreas-Endocrine-3m|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HSP90B1 CCDC88A TAX1BP1 GRIA2 ANKH

1.10e-05191685b3de0393d6510543533cd851e47a0f95739a0e4e
ToppCellMyeloid-Myeloid-B_(Activated_Macrophage)|Myeloid / shred on cell class and cell subclass (v4)

HSP90B1 CCDC88A DSTN SMC6 PEX11A

1.10e-051916857bf125249af1e8bb138ed4d999fdd74b03ab2447
ToppCellmoderate-Epithelial-FOXN4+|Epithelial / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls

CNOT10 SANBR UTRN DEUP1 KNL1

1.18e-05194685dff3fb10372053951d41e0ccd41aac3ece6009bd
ToppCellsevere-CD8+_Tem|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

DNAJB1 HSP90B1 DSTN MYO6 SYTL2

1.37e-052006856aa77955017d073a96324e4db6b9950a2ec46cf8
ToppCellfrontal_cortex-Neuronal-GABAergic_neuron-Sst-Sst_Esm1|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

STK32A PLA2G7 STK32B CREB3L2

3.55e-05121684056d0f0f7a4d1b2d38b83647bbe4468b7c959ce6
ToppCellHippocampus-Macroglia-POLYDENDROCYTE-P5-P5_2-Sox4-POLYDENDROCYTE_(Neurogenesis.Sox4.Gad2)|Hippocampus / BrainAtlas - Mouse McCarroll V32

SEC16B TRPM1 PSTPIP1 KNL1

3.90e-051246841483be8700eca7e2c288784a290d945d4022b17f
ToppCellprimary_visual_cortex-Neuronal-GABAergic_neuron-Sst-Sst_Crh_4930553C11Rik_|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

STK32A PLA2G7 STK32B CREB3L2

6.44e-05141684ad9a25569c142fb68ded34aeba0cd9be8124ce56
ToppCellPND14-Immune-Immune_Lymphocytic_T/NK-Lymphocytic_T-CD4_T-CD4_T_prolif|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

WFIKKN2 TRPM1 DNAJC2 HELB

8.19e-051506847bc61eb4b8c4a1909f4b7bcd1c6a88ef46102669
ToppCell356C-Myeloid-Macrophage-SPP1+_Macrophage_2|Macrophage / Donor, Lineage, Cell class and subclass (all cells)

C10orf67 STK32B ANKH FILIP1L

9.77e-051576847ceae5fe00c91d4feb8c314d3a31f027c03fa56f
ToppCellfrontal_cortex-Neuronal-GABAergic_neuron-Sst|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

STK32A STK32B UTRN CREB3L2

1.08e-04161684dccb61d5e17a8f1c6d1fc146ee389f567659a0f0
ToppCellStriatum-Endothelial-MURAL-M1(Rgs5Acta2)-M1_3|Striatum / BrainAtlas - Mouse McCarroll V32

DSTN RGS5 TAX1BP1 FILIP1L

1.16e-04164684e24b06a14565f7798ac50c2fe3f34d4547b9000e
ToppCellSigmoid-Macrophage-Macrophage|Macrophage / Region, Cell class and subclass

PLA2G7 UTRN ANKH FILIP1L

1.27e-04168684bb16e135b6ae0d66615420b61edd6f62f2a3233c
ToppCell5'-GW_trimst-1.5-LargeIntestine-Mesenchymal-fibroblastic-Stromal_1_(ADAMDEC1+)|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

DNAJB1 PROM1 ZNF492 KNL1

1.33e-04170684a7184dc41f90caa753860ed0f65a18133f84bc5f
ToppCellprimary_visual_cortex-Neuronal-GABAergic_neuron-Sst|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

STK32A STK32B UTRN CREB3L2

1.33e-041706848ab67e2b6e30fdf9e9a2c02e31d4df34e751a3ed
ToppCellTCGA-Lung-Primary_Tumor-Lung_Carcinoma-Lung_Adenocarcinoma_Mixed_Subtype-4|TCGA-Lung / Sample_Type by Project: Shred V9

STK32A SH3KBP1 SYTL2 CREB3L2

1.52e-041766840923b01137d6f9956ca815b41102c81e82624065
ToppCellFetal_29-31_weeks-Mesenchymal-vascular_smooth_muscle_cell-D150|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

RGS5 SYTL2 GRIA2 FILIP1L

1.58e-04178684066dbc4cc2083c549d98122ed44707127f34d582
ToppCelldroplet-Limb_Muscle-MUSCLE-30m|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TAX1BP1 BAZ1B UTRN FILIP1L

1.58e-0417868401dafd19de04eff459253eaa9a35debf8f3deedf
ToppCellfacs-Brain_Non-Myeloid-Cerebellum-24m-Mesenchymal|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

C20orf96 RGS5 CCDC81 FILIP1L

1.58e-041786847467e5ab2fcb39cc4a2c7dd69722c91def3b6aea
ToppCellfacs-Lung-EPCAM-24m-Myeloid-Dendritic_Cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DDX60 SYTL2 NFXL1 MPP7

1.65e-041806845b7d2336ed09d07f6b8dd91c1fa9c5ade633c104
ToppCellfacs-Lung-24m-Hematologic-myeloid-myeloid_dendritic_cell-dendritic_cell|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

DDX60 SYTL2 NFXL1 MPP7

1.65e-04180684d33bb00f2b7d07dda9015cb8eafd742c2b2e9ace
ToppCelldroplet-Lung-1m-Endothelial-arterial_endothelial-pulmonary_artery_endothelial_cell-pulmonary_artery_endothelial_cell_l25|1m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

PROM1 UTRN RYK CREB3L2

1.69e-04181684136b0c60680068838d184d32aa99d7bea8718dbc
ToppCelldroplet-Marrow-nan-3m-Hematologic-nan|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MYO6 SH3KBP1 SYTL2 UTRN

1.72e-04182684e78ba2c5cae480c16a596ce7c3bf2d480becacf4
ToppCellPrimary_Motor_Cortex_(M1)-Non-neuronal-Macroglial-Oligo-OPC-OPC_L1-6_MYT1|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

STK32A PROM1 DDX60 STK32B

1.72e-04182684a05e5978ef5f7fac7eeb2ba1c0103ea90d5e9136
ToppCelldroplet-Marrow-nan-3m-Hematologic|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MYO6 SH3KBP1 SYTL2 UTRN

1.72e-041826841710eab3037a87609d21838be2d2d29c3bc36651
ToppCellPrimary_Motor_Cortex_(M1)-Non-neuronal-Macroglial-Oligo-OPC|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

STK32A PROM1 DDX60 STK32B

1.72e-04182684831b5ce46b41efe01c4db6016c2f43148611373d
ToppCellLA-07._Pericyte|World / Chamber and Cluster_Paper

RGS5 GRK5 SYTL2 UTRN

1.76e-04183684e3835db4795362b0442d5893baf2a78efcc20428
ToppCell3'-GW_trimst-2-SmallIntestine-Mesenchymal-stromal_related-ICC|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

MYO6 RGS5 WFIKKN2 LRP1B

1.76e-04183684262387ee8d43b96e5f1a77c75124459a506a6172
ToppCell3'-GW_trimst-2-SmallIntestine-Mesenchymal-stromal_related|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

MYO6 RGS5 WFIKKN2 LRP1B

1.76e-04183684c85a707acbcb582912e8ac080a36d05f91cfd7a2
ToppCelldroplet-Kidney-KIDNEY-1m-Epithelial-Epcam____podocyte-2|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

STK32A STK32B TRPM1 UTRN

1.80e-04184684e123ad8ee46a032825a0bd4b3586ddcb3eda03d4
ToppCelldroplet-Marrow-nan-3m-Lymphocytic-late_pro-B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ATF6 SETBP1 RYK CREB3L2

1.80e-0418468442cadfdb5d29a50bd7e901ddd14d42b39e8474f0
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Cortical_Thick_Ascending_Limb_Cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

STK32A STK32B LRP1B CREB3L2

1.80e-04184684e8238fe58f94b4f5700ab7f343fb06ea61e899a9
ToppCellCOVID-19-Heart-Pericyte|Heart / Disease (COVID-19 only), tissue and cell type

RGS5 GRK5 SETBP1 SYTL2

1.80e-0418468421790cdfa3b4036ad413fd44b94e31563116f25f
ToppCellprimary_auditory_cortex_(A1C)-Non-neuronal-Macroglial-Oligo-OPC-OPC_L1-6_MYT1|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

STK32A PROM1 DDX60 STK32B

1.83e-04185684efc5d564f8793c751ba640aef60f761e4b081d3f
ToppCellChildren_(3_yrs)-Epithelial-alveolar_epithelial_cell_type_1|Children_(3_yrs) / Lineage, Cell type, age group and donor

DSTN C10orf67 GRK5 EFR3B

1.83e-041856841c222f7285d6e3dae0354dc7e853ddc0ea55e63e
ToppCellFetal_29-31_weeks-Mesenchymal-chondrocyte-D150|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

STK32A STK32B WFIKKN2 GRIA2

1.83e-041856848ed10ba581849c9c4ac4397226be2b62b4b3b900
ToppCellprimary_auditory_cortex_(A1C)-Non-neuronal-Macroglial-Oligo-OPC|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

STK32A PROM1 DDX60 STK32B

1.83e-04185684fba2dc46cd98ab9c78e788959c2121aa10d148b2
ToppCellFetal_29-31_weeks-Mesenchymal-chondrocyte|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

STK32A STK32B WFIKKN2 GRIA2

1.83e-04185684b8052cebb73f41abe6faf0aa847be7c8ef23ae94
ToppCelldroplet-Spleen-nan-3m|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SH3KBP1 SMC6 UTRN FILIP1L

1.87e-0418668426f1e9930adf2fe4af0819e56f69915bd8330e4a
ToppCelldroplet-Spleen-nan-3m-Lymphocytic|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SH3KBP1 SMC6 UTRN FILIP1L

1.91e-0418768491c8e93bde0d1d1a4e324b0acf2afda00f4fb3bf
ToppCellPrimary_Visual_cortex_(V1C)-Non-neuronal-Macroglial-Oligo-OPC|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

STK32A PROM1 DDX60 STK32B

1.91e-04187684daff7ccd3f1924cf2b34d3aca3eccde245aaf371
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Cortical_Thick_Ascending_Limb_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

STK32A STK32B LRP1B CREB3L2

1.91e-041876847ea8731288e2a99f45e3958590ee1d76f49ae888
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Distal_tubule_epithelial_cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

DSTN MYO6 SYTL2 LRP1B

1.91e-0418768477886f99c229610abd28c4c370d2c7d1536c9782
ToppCelldroplet-Spleen-nan-3m-Lymphocytic-nan|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SH3KBP1 SMC6 UTRN FILIP1L

1.91e-04187684382db691eb0b3e089e816bed3d6699cc2d4e1bda
ToppCellPrimary_Visual_cortex_(V1C)-Non-neuronal-Macroglial-Oligo-OPC-OPC_L1-6_MYT1|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

STK32A PROM1 DDX60 STK32B

1.91e-041876845b7a1edee602e55d3400dc17dbb6b8aaa26defc0
ToppCellCOVID-19-lung-Plasma_cells_PRDM1/BLIMP_int|COVID-19 / Disease (COVID-19 only), tissue and cell type

DNAJB1 HSP90B1 KNL1 CREB3L2

1.95e-04188684599195338070ac6b79bd114609d9e10cac4f1df4
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Cortical_Thick_Ascending_Limb_Cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

STK32A STK32B LRP1B CREB3L2

1.95e-041886842ee64bc73a2251fd9f374be759b442cf4ed0d19e
ToppCellAdult-Epithelial-alveolar_epithelial_cell_type_1-D231|Adult / Lineage, Cell type, age group and donor

STK32A DSTN GRK5 EFR3B

1.99e-041896845a04cb25f8f0447b2cecdb6c3695029281aca26d
ToppCell3'-GW_trimst-1.5-LargeIntestine-Mesenchymal-myocytic-SMC_(PLPP2+)|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

DSTN RGS5 SETBP1 FILIP1L

2.03e-04190684e102622f05c7f3e1bd8b224ea159d57033793ee0
ToppCellIPF-Lymphoid-T|IPF / Disease state, Lineage and Cell class

GRK5 SYTL2 MPP7 HELB

2.03e-04190684d57df208aaf7a5554899bb9107c80b443fd0cf93
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Cortical_Thick_Ascending_Limb_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

STK32A STK32B LRP1B CREB3L2

2.03e-04190684cc17ab84a9328124f146951c06be3eff9650d9fd
ToppCell3'-GW_trimst-1.5-LargeIntestine-Mesenchymal-myocytic|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

DSTN RGS5 SETBP1 FILIP1L

2.07e-04191684de2cd94ee88a7754f86d39469e38374d668210c7
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Cortical_Thick_Ascending_Limb_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

STK32A STK32B LRP1B CREB3L2

2.07e-04191684963f4f2e852bbb4faf070aafb0d368297abacd3b
ToppCellPBMC_fresh-frozen-Mild-Moderate_progression_d02_child-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell|Mild-Moderate_progression_d02_child / Compartment, severity and other cell annotations on 10x 3' data (130k)

DNAJB1 NFXL1 ANKH HELB

2.11e-041926841c0ce299cee9ab5cdea256f3e8c1e5598577a8b6
ToppCellCOPD-Lymphoid-T|World / Disease state, Lineage and Cell class

GRK5 SYTL2 MPP7 HELB

2.11e-04192684eb4909574fb5fc91399463523e2737095773200a
ToppCellH1299-infected|H1299 / Cell line, Condition and Strain

BPTF CCDC88A BAZ1B DNAJC2

2.11e-041926849cf8049bdc3e0f81ce69042beac72b08d8f38b4e
ToppCellCOPD-Lymphoid|COPD / Disease state, Lineage and Cell class

GRK5 SH3KBP1 SYTL2 MPP7

2.11e-04192684064fefb8212fadab0ff441f4bf643559b7fdb25d
ToppCellCOVID-19-Heart-Fib_+_EC_+_Pericyte|Heart / Disease (COVID-19 only), tissue and cell type

RGS5 GRK5 SETBP1 CREB3L2

2.11e-0419268460b1312e84f6d6448365a952469c506c00b5fe93
ToppCellIPF-Lymphoid-T|World / Disease state, Lineage and Cell class

GRK5 SYTL2 MPP7 HELB

2.11e-04192684b25ba1f3bc842c22602b2aeed3b1b5082863e4fa
ToppCelldroplet-Bladder-nan-3m-Endothelial-endothelial_cell|Bladder / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PROM1 RGS5 EFR3B FILIP1L

2.16e-041936848be24713f8ba2545b7647d1994e9e993623ddaa3
ToppCelldroplet-Bladder-nan-3m-Endothelial-endothelial_cell|Bladder / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PROM1 RGS5 EFR3B FILIP1L

2.16e-0419368419dfc4a2c91fcea4f5991e7c44df46faeecb06b8
ToppCelldroplet-Bladder-nan-3m-Endothelial|Bladder / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PROM1 RGS5 EFR3B FILIP1L

2.16e-04193684351e0acd411a9eb0dbc0e358d0d1e3759753fa40
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Epithelial|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

PROM1 MYO6 STK32B LRP1B

2.24e-041956846477e6e7be5bd8eb99119a12ae16334ccddecd43
ToppCellCOPD-Lymphoid-T|COPD / Disease state, Lineage and Cell class

GRK5 SYTL2 MPP7 HELB

2.29e-0419668430e53b8050d2a041f855d0e39bbd8f923c64c489
ToppCellMild|World / Disease group and Cell class

DDX60 MKRN1 UTRN HELB

2.29e-041966845e4ed4a5a437cfa002b92775992a791e27aa4c27
ToppCellMatrixFB-Fibroblast-B_(Myofibroblast)|MatrixFB / shred on cell class and cell subclass (v4)

HSP90B1 DSTN FILIP1L CREB3L2

2.29e-0419668438ea0eaf42f95c321ca23570d0d7752980cf00f8
ToppCellP07-Mesenchymal-myocytic_cell|P07 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

RGS5 RYK FILIP1L CREB3L2

2.33e-04197684378299fe2ec6ed2fc858febb78ff1ac0898e457d
ToppCellCOVID_non-vent-Lymphocytic-T_cell-CD8+_Memory_T_cell|COVID_non-vent / Disease condition, Lineage, Cell class and subclass

DSTN MYO6 SYTL2 UTRN

2.33e-04197684836061acd7f0d5de89b16f52ec679bdf09eac9db
ToppCellParenchymal-NucSeq-Epithelial-Epi_alveolar-AT1|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

DSTN C10orf67 GRK5 EFR3B

2.33e-041976848d5097898dd01cedb04cb694cb480c931e08462c
ToppCellPND10-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_airway|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

HSP90B1 RYK FILIP1L CREB3L2

2.33e-0419768426475b9e4d6bfc0ae818dea13d139888ed7e92f1
ToppCellkidney_cells-Adult_normal_reference-Mesenchymal-Myocytic_interstitial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

DSTN GRIA2 UTRN FILIP1L

2.33e-041976848b3bf5b45e49bf1c60e4d2703b470bb890385f67
ToppCellTransverse-Dendritic_cell-Lymphoid_DC|Dendritic_cell / Region, Cell class and subclass

MYO6 SYTL2 CCDC81 RYK

2.33e-041976848545baf923ddf84c5ce9414a36d810603be52401
ToppCellkidney_cells-Adult_normal_reference-Mesenchymal|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

DSTN GRIA2 UTRN FILIP1L

2.33e-0419768402e70768a917c5f097bc653e9e965a1000289d2e
ToppCellTransverse-(5)_Dendritic_cell-(53)_Lymphoid_DC|Transverse / shred on region, Cell_type, and subtype

SANBR CCDC81 RYK FILIP1L

2.33e-0419768415b87fd3906d7388c271d30d0c64b1bcc490801c
ToppCellH1299-infected-SARSCoV2|infected / Cell line, Condition and Strain

CCDC88A MYO6 DNAJC2 NOL8

2.33e-041976840fa3e4cf93e77d78b1f97b906c5b13ca741ae17e
ToppCellPND10-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_airway-SCMF|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

HSP90B1 RYK FILIP1L CREB3L2

2.33e-04197684155e63b33302a87393ace699b2f6d73abe9c5763
ToppCellTransverse-Dendritic_cell-Lymphoid_DC|Transverse / Region, Cell class and subclass

SANBR CCDC81 RYK FILIP1L

2.33e-04197684a58af0ea82f76f2a7abac1f62629ff20d552fc63
ToppCellPND10-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_airway-SCMF-SCMF_mature|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

HSP90B1 RYK FILIP1L CREB3L2

2.38e-04198684a4005a49cf6709b543994ceb51ecd5dc46197fa9
ToppCellPND10-Mesenchymal-Mesenchymal_myocytic|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

DSTN RYK FILIP1L CREB3L2

2.38e-04198684a699b365d3b6149f13f02b2e2ae9b6fdce761848
ToppCellnormal_Lung-Fibroblasts-Smooth_muscle_cells|Fibroblasts / Location, Cell class and cell subclass

DSTN RGS5 SYTL2 FILIP1L

2.42e-04199684d65847ceb68a560798df3f73e6f838e7c3e38a1c
ToppCellmild-low-quality_cells|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

BPTF SYTL2 UTRN HELB

2.42e-04199684f0b0097df0026496470a80d8cc9375ffd8389b00
ToppCell(00)_Basal-(2)_GFP_FOXI1|(00)_Basal / shred by cell type by condition

BPTF CCDC88A NAA15 MYO6

2.42e-0419968419674e1eaeb51e4196d847cb62aa437c852951d3
ToppCell10x_3'_v3-spleen_(10x_3'_v3)-lymphocytic-T_lymphocytic-naive_thymus-derived_CD8-positive,_alpha-beta_T_cell|spleen_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

DNAJB1 DSTN MYO6 SYTL2

2.42e-04199684db05c16d80f5a74bfa048a5c92917d312d26f769
ToppCell(04)_Interm._basal>secr.-(2)_GFP_FOXI1|(04)_Interm._basal>secr. / shred by cell type by condition

BPTF NAA15 MYO6 TAX1BP1

2.42e-0419968453ca3861f9e00dab3f3fbefb0837857ee39ab084
ToppCellmild-CD4+_Tcm|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

DNAJB1 TLK1 DDX60 HELB

2.42e-0419968406c8a0e39f7a33736548f04a5e2263334c8541cf
ToppCellmild-MAIT|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

DNAJB1 DDX60 SYTL2 UTRN

2.42e-04199684cbe1fb6d2c5fca7a1baf1ad20afcdf8e8e11bd84
ToppCell3'-GW_trimst-1.5-SmallIntestine-Mesenchymal-fibroblastic-Stromal_2_(NPY+)|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

PROM1 GRK5 LANCL2 FILIP1L

2.42e-0419968405777e92344aedabfb5a72207c6632dc64205534
ToppCellsevere-gd_T|severe / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

HSP90B1 DSTN MYO6 SYTL2

2.42e-04199684e5a17a9f8f3be05d6abe1116607d17633df3c7ef
ToppCell(01)_IL1RL1+-(2)_GFP_FOXI1|(01)_IL1RL1+ / shred by cell type by condition

BPTF CCDC88A NAA15 SMC6

2.42e-04199684a2f7d0cabf35b80fe239fae34a77bf9344d5d743
ToppCellmild-CD8+_Tem|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

MYO6 DDX60 SYTL2 UTRN

2.47e-04200684d8aec4904c9420b8f9d7508658ba1e36c66cdfcc
ToppCellproximal-mesenchymal-Vascular_Smooth_Muscle-3|proximal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

RGS5 GRK5 SYTL2 FILIP1L

2.47e-042006845c0135d3cb6f7fa904e9760904dfe5f11c7e9102
ToppCellCaecum|World / Region, Cell class and subclass

DNAJB1 HSP90B1 SYTL2 CREB3L2

2.47e-04200684f8e3285f5ea7fef1b7b7089bd8b0f1ddb0625dfb
ToppCellproximal-3-mesenchymal-Vascular_Smooth_Muscle|3 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

RGS5 GRK5 SYTL2 FILIP1L

2.47e-04200684870ab11343711f64fe6d6a858fc420fe17f1636a
ToppCellsevere-gd_T|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

HSP90B1 DSTN MYO6 SYTL2

2.47e-042006842253d74049cc49c92e897ff4aa298d913daeb739
ToppCellParenchymal-10x3prime_v2-Immune_Myeloid-Myeloid-Megakaryocyte|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations

DNAJB1 GRK6 SYTL2 ANKH

2.47e-042006840d76b006d8e8b32174e65e400acd0674354b962c
ToppCellVE|World / Condition, Cell_class and T cell subcluster

BPTF DDX60 GRK6 UTRN

2.47e-042006848ae7cb81de3ffac5acdf3466d4b516d80cac95d3
ToppCellParenchymal-10x3prime_v2-Immune_Myeloid-Myeloid|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations

DNAJB1 GRK6 SYTL2 ANKH

2.47e-04200684cc8368665bc6bb7c4f39632ccff07ceaa98a7b65
ComputationalSignaling.

PROM1 SLC10A1 ING1 GRK5 SETBP1 FILIP1L

1.90e-04219426MODULE_129
Diseaseplatelet reactivity measurement, thrombus formation measurement

RGS5 SETBP1

9.06e-057622EFO_0004985, EFO_0007615
DiseaseQRS duration, response to sulfonylurea

LRRC63 LANCL2

1.07e-0323622EFO_0005055, EFO_0007922
DiseaseCone-Rod Dystrophy 2

PROM1 ATF6

1.70e-0329622C3489532
DiseaseR-6-hydroxywarfarin measurement

ZFP42 DDX60 LRP1B

1.80e-03114623EFO_0803327
DiseaseParkinson's disease (biomarker_via_orthology)

GRK5 GRK6

1.82e-0330622DOID:14330 (biomarker_via_orthology)
DiseaseHuntington disease, disease progression measurement

TRPM1 EFR3A

1.82e-0330622EFO_0008336, MONDO_0007739
Diseasecoronary aneurysm

GRK5 SETBP1

2.47e-0335622EFO_1000881
DiseaseAPOE carrier status, cerebral amyloid angiopathy

SETBP1 EFR3A

3.54e-0342622EFO_0006790, EFO_0007659
Diseasebody fat percentage

BPTF SEC16B MKRN1 SETBP1 FILIP1L

3.62e-03488625EFO_0007800
Diseaseage at menopause

TLK1 ZFP42 GRK6 HELB

3.77e-03302624EFO_0004704

Protein segments in the cluster

PeptideGeneStartEntry
EKMRKVYLAKEKNTS

CXorf58

296

Q96LI9
ASMSEEQRKEYLKKK

BAZ1B

536

Q9UIG0
CQSRKKKKEYMLGLE

ATF6

321

P18850
YDMKVRKCSTPEEIK

DSTN

16

P60981
KQKVSDMKYKAVRTE

DEUP1

411

Q05D60
KEYSTRDKVKLMKFS

BPTF

1806

Q12830
YSGCTKKMKISHKRL

DNAJB1

176

P25685
GRTKKDCMKRYKELV

DNAJC2

586

Q99543
KREKICRQDTSFMKK

EFR3A

511

Q14156
CMETHYEKVLKKVSK

GOLGA7

81

Q7Z5G4
MTKEKYGKECKICAR

RBM22

36

Q9NW64
KAMESKKTYEQKCRD

PSTPIP1

136

O43586
EKKKCKMSYLEQQAE

C20orf96

181

Q9NUD7
KKTCYEMKKFLLYAR

LRP1B

1566

Q9NZR2
TCKEMKRKASEIKEA

NFXL1

826

Q6ZNB6
KVFKEEKYLKEAMEC

LANCL2

336

Q9NS86
KLVIKKMDARKYEES

DDX60

1061

Q8IY21
LYSSKKDDKMKEISR

LINC00474

11

Q9P2X8
PKDKDKMKACYRRSM

CCDC88A

1476

Q3V6T2
CYKSRAEAKRMKVAK

GRIA2

836

P42262
VKAAMRKVVTKYILC

OR4M1

296

Q8NGD0
KVDKCSRQDTVFMKK

EFR3B

506

Q9Y2G0
LSRKDKKTNKSMYEC

MPP7

326

Q5T2T1
YLKVEEVVTKCKIKM

MYNN

101

Q9NPC7
YLNKIKSCFTKMTKV

KNL1

1996

Q8NG31
SRKFKTMKDVYTEKR

LRRC63

131

Q05C16
VGCLYEKESMKKSLK

NOL8

576

Q76FK4
SKCAKYMLKANLIKE

NAA15

446

Q9BXJ9
MKKCYSPDKERKMIT

PLA2G7

331

Q13093
CYEKFKTPKDKTKMI

SLC10A1

306

Q14973
RKTLDMIKKIADDKY

HSP90B1

466

P14625
RYKSFSIKILKDMKE

ERVK-9

306

P63126
SKVPKKDFEKVCMEY

IGSF22

196

Q8N9C0
IDCKKFAKDMRSLDK

DNAH17

1311

Q9UFH2
KFLKDKMEETQCYKR

CCDC81

471

Q6ZN84
KMYSVTKERDDLKNK

FILIP1L

556

Q4L180
IAACYVYRKQKKKME

ANKH

446

Q9HCJ1
RATGKMYACKRLEKK

GRK5

206

P34947
RATGKMYACKKLEKK

GRK6

206

P43250
RKMCYKKLEEVKTSA

RYK

191

P34925
TVDFKKLMKYCRIKH

HELB

866

Q8NG08
SRRKKKEYMDSLEKK

CREB3L2

311

Q70SY1
KLILKYKEAMSNKAC

MKRN1

356

Q9UHC7
EAYKMCTEKIQEKKI

HMG20B

141

Q9P0W2
KARKMIYKSTDLNKD

SYTL2

236

Q9HCH5
DKCMKLYKTLSEVKL

UTRN

1476

P46939
KCNKYADELAKMELK

TAX1BP1

551

Q86VP1
KMYHQLKKCETRKLS

SMG5

261

Q9UPR3
ACEDYKKIKSPAKMA

RGS5

96

O15539
TMDKALEKSKKERAY

ING1

406

Q9UK53
KMKLTFEQVYSDCKK

PROM1

551

O43490
EMDSRTKSKDYCKVI

SH3KBP1

261

Q96B97
MKRVTCDRAKKEKSA

PEX11A

146

O75192
KVCIVQKNDTKKMYA

STK32A

36

Q8WU08
KYIKRNTKENKDCEM

SANBR

206

Q6NSI8
RYKSFSIKILKDMKE

ERVK-9

306

P63128
KEDKEMRKKYGSLSV

C10orf67

331

Q8IYJ2
YIQMKSLKACKREIK

CNOT10

226

Q9H9A5
EKYKERLNKCISMSK

TLK1

261

Q9UKI8
KFSEKISCVHMKRKY

SSX6P

41

Q7RTT6
EAYNKCIKDYMKSIK

nan

91

Q56UQ5
CIKDYMKSIKGKLEE

nan

96

Q56UQ5
CMALKADVVAKKRAY

SMC6

346

Q96SB8
AELLMQDCKKLEKYK

SEC16B

386

Q96JE7
LECSLEYMKKGVKKE

ZFP42

116

Q96MM3
EESMAKALVACKLYK

TRPM1

636

Q7Z4N2
LRKYCKSMDECKVHK

ZNF492

81

Q9P255
KVCIVQKRDTKKMYA

STK32B

36

Q9NY57
VRKMCNYTKILSTKK

SETBP1

1411

Q9Y6X0
KIKKLEKETTMYRSR

TXLNA

421

P40222
KSCVAARYMDVKGKK

WFIKKN2

86

Q8TEU8
LKNKIKYRAEACIKM

MYO6

806

Q9UM54