Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	Pyrin domain binding	NLRP7 NLRP2	3.32e-05	3	67	2	GO:0032090
GeneOntologyMolecularFunction	mannosyl-oligosaccharide 1,2-alpha-mannosidase activity	MAN1A2 MAN1A1	3.07e-04	8	67	2	GO:0004571
GeneOntologyMolecularFunction	aspartic-type endopeptidase inhibitor activity	NLRP7 NLRP2	3.93e-04	9	67	2	GO:0019828
GeneOntologyMolecularFunction	mannosyl-oligosaccharide mannosidase activity	MAN1A2 MAN1A1	4.91e-04	10	67	2	GO:0015924
GeneOntologyMolecularFunction	interleukin-1 binding	NLRP7 NLRP2	7.16e-04	12	67	2	GO:0019966
GeneOntologyMolecularFunction	alpha-mannosidase activity	MAN1A2 MAN1A1	1.13e-03	15	67	2	GO:0004559
GeneOntologyMolecularFunction	DNA helicase activity	SETX MCM2 MCM3	1.19e-03	62	67	3	GO:0003678
GeneOntologyMolecularFunction	caspase binding	NLRP7 NLRP2	1.29e-03	16	67	2	GO:0089720
GeneOntologyMolecularFunction	mannosidase activity	MAN1A2 MAN1A1	1.29e-03	16	67	2	GO:0015923
GeneOntologyBiologicalProcess	nuclear cell cycle DNA replication initiation	MCM2 MCM3	1.03e-04	5	67	2	GO:1902315
GeneOntologyBiologicalProcess	mitotic DNA replication initiation	MCM2 MCM3	1.03e-04	5	67	2	GO:1902975
GeneOntologyBiologicalProcess	cell cycle DNA replication initiation	MCM2 MCM3	1.03e-04	5	67	2	GO:1902292
GeneOntologyBiologicalProcess	premeiotic DNA replication	MCM2 MCM3	1.55e-04	6	67	2	GO:0006279
GeneOntologyBiologicalProcess	motile cilium assembly	FSIP2 CFAP206 CFAP70 JHY	1.93e-04	88	67	4	GO:0044458
GeneOntologyBiologicalProcess	ubiquitin-dependent glycoprotein ERAD pathway	MAN1A2 MAN1A1	2.87e-04	8	67	2	GO:0097466
GeneOntologyBiologicalProcess	protein deglycosylation involved in glycoprotein catabolic process	MAN1A2 MAN1A1	2.87e-04	8	67	2	GO:0035977
GeneOntologyBiologicalProcess	mannose trimming involved in glycoprotein ERAD pathway	MAN1A2 MAN1A1	2.87e-04	8	67	2	GO:1904382
GeneOntologyBiologicalProcess	protein alpha-1,2-demannosylation	MAN1A2 MAN1A1	2.87e-04	8	67	2	GO:0036508
GeneOntologyBiologicalProcess	protein demannosylation	MAN1A2 MAN1A1	2.87e-04	8	67	2	GO:0036507
GeneOntologyCellularComponent	chromosome, telomeric region	SETX NLRP7 SUN1 MCM2 MCM3 NLRP2	2.53e-05	176	69	6	GO:0000781
GeneOntologyCellularComponent	pericentriolar material	TCP1 TUBG2 CEP152	1.06e-04	28	69	3	GO:0000242
GeneOntologyCellularComponent	MCM complex	MCM2 MCM3	5.79e-04	11	69	2	GO:0042555
GeneOntologyCellularComponent	CMG complex	MCM2 MCM3	5.79e-04	11	69	2	GO:0071162
GeneOntologyCellularComponent	outer dynein arm	DNAI2 CFAP70	6.94e-04	12	69	2	GO:0036157
GeneOntologyCellularComponent	DNA replication preinitiation complex	MCM2 MCM3	8.18e-04	13	69	2	GO:0031261
Domain	TCEAL1	TCEAL7 TCEAL4 TCEAL2	3.82e-06	9	68	3	IPR010370
Domain	TF_A-like/BEX	TCEAL7 TCEAL4 TCEAL2	1.63e-05	14	68	3	IPR021156
Domain	BEX	TCEAL7 TCEAL4 TCEAL2	1.63e-05	14	68	3	PF04538
Domain	MCM_N	MCM2 MCM3	1.94e-04	6	68	2	IPR027925
Domain	MCM_N	MCM2 MCM3	1.94e-04	6	68	2	PF14551
Domain	MCM_CS	MCM2 MCM3	1.94e-04	6	68	2	IPR018525
Domain	Glyco_hydro_47	MAN1A2 MAN1A1	2.71e-04	7	68	2	PF01532
Domain	-	MAN1A2 MAN1A1	2.71e-04	7	68	2	1.50.10.50
Domain	MCM_OB	MCM2 MCM3	3.61e-04	8	68	2	IPR033762
Domain	MCM_2	MCM2 MCM3	3.61e-04	8	68	2	PS50051
Domain	MCM_1	MCM2 MCM3	3.61e-04	8	68	2	PS00847
Domain	MCM_OB	MCM2 MCM3	3.61e-04	8	68	2	PF17207
Domain	Glyco_hydro_47	MAN1A2 MAN1A1	3.61e-04	8	68	2	IPR001382
Domain	MCM	MCM2 MCM3	4.63e-04	9	68	2	SM00350
Domain	MCM_dom	MCM2 MCM3	4.63e-04	9	68	2	IPR001208
Domain	MCM	MCM2 MCM3	4.63e-04	9	68	2	IPR031327
Domain	MCM	MCM2 MCM3	4.63e-04	9	68	2	PF00493
Domain	-	ARID3A KDM5A	1.33e-03	15	68	2	1.10.150.60
Domain	BRIGHT	ARID3A KDM5A	1.33e-03	15	68	2	SM00501
Domain	ARID_dom	ARID3A KDM5A	1.33e-03	15	68	2	IPR001606
Domain	ARID	ARID3A KDM5A	1.33e-03	15	68	2	PS51011
Domain	ARID	ARID3A KDM5A	1.33e-03	15	68	2	PF01388
Domain	DAPIN	NLRP7 NLRP2	2.88e-03	22	68	2	PS50824
Domain	PYRIN	NLRP7 NLRP2	2.88e-03	22	68	2	PF02758
Domain	DAPIN	NLRP7 NLRP2	2.88e-03	22	68	2	IPR004020
Domain	PYRIN	NLRP7 NLRP2	2.88e-03	22	68	2	SM01289
Domain	NACHT	NLRP7 NLRP2	3.15e-03	23	68	2	PS50837
Domain	NACHT_NTPase	NLRP7 NLRP2	3.15e-03	23	68	2	IPR007111
Pathway	REACTOME_N_GLYCAN_TRIMMING_AND_ELONGATION_IN_THE_CIS_GOLGI	MAN1A2 MAN1A1	1.27e-04	5	51	2	M27954
Pathway	REACTOME_N_GLYCAN_TRIMMING_AND_ELONGATION_IN_THE_CIS_GOLGI	MAN1A2 MAN1A1	1.27e-04	5	51	2	MM15670
Pubmed	Genetic analysis of the proximal portion of the mouse t complex: evidence for a second inversion within t haplotypes.	TCP1 TBXT ITPR3	2.84e-07	7	71	3	3455895
Pubmed	Genetic interactions between doublecortin and doublecortin-like kinase in neuronal migration and axon outgrowth.	RELN MAPT DCLK1	6.79e-07	9	71	3	16387638
Pubmed	INVESTIGATIONS OF THE NATURE OF T-ALLELES IN THE MOUSE. I. GENETIC ANALYSIS OF A SERIES OF MUTANTS DERIVED FROM A LETHAL ALLELE.	TBXT ITPR3	4.11e-06	2	71	2	14167577
Pubmed	Genetic mapping of the human homologue (T) of mouse T(Brachyury) and a search for allele association between human T and spina bifida.	TCP1 TBXT	4.11e-06	2	71	2	8733136
Pubmed	The Effects of Alpha Boswellic Acid on Reelin Expression and Tau Phosphorylation in Human Astrocytes.	RELN MAPT	4.11e-06	2	71	2	27567921
Pubmed	NLRP2 controls age-associated maternal fertility.	NLRP7 NLRP2	4.11e-06	2	71	2	27881734
Pubmed	NLRP2 is highly expressed in a mouse model of ischemic stroke.	NLRP7 NLRP2	4.11e-06	2	71	2	27693696
Pubmed	Curtailed, a new dominant T-allele in the house mouse.	TBXT ITPR3	4.11e-06	2	71	2	5906493
Pubmed	Motor and cognitive stereotypies in the BTBR T+tf/J mouse model of autism.	TBXT ITPR3	4.11e-06	2	71	2	21040460
Pubmed	A major testicular cell protein specified by a mouse T/t complex gene.	TCP1 TBXT	4.11e-06	2	71	2	455464
Pubmed	Reproductive Outcomes from Maternal Loss of Nlrp2 Are Not Improved by IVF or Embryo Transfer Consistent with Oocyte-Specific Defect.	NLRP7 NLRP2	4.11e-06	2	71	2	33090377
Pubmed	A genetic association study of NLRP2 and NLRP7 genes in idiopathic recurrent miscarriage.	NLRP7 NLRP2	4.11e-06	2	71	2	23360675
Pubmed	Splicing factor SC35 promotes tau expression through stabilization of its mRNA.	SRSF2 MAPT	4.11e-06	2	71	2	21333649
Pubmed	Gene mapping within the T/t complex of the mouse. III: t-Lethal genes are arranged in three clusters on chromosome 17.	TBXT ITPR3	4.11e-06	2	71	2	6509553
Pubmed	Molecular probes define different regions of the mouse t complex.	TBXT ITPR3	4.11e-06	2	71	2	2981632
Pubmed	An alpha globin pseudogene is located within the mouse t complex.	TCP1 ITPR3	4.11e-06	2	71	2	6321339
Pubmed	Brachyury and the T-box genes.	TBXT ITPR3	4.11e-06	2	71	2	9309177
Pubmed	An additional type of male sterility and inherited urinary obstruction in mice with the t-haplotype th7.	TBXT ITPR3	4.11e-06	2	71	2	8690273
Pubmed	Nlrp2, a maternal effect gene required for early embryonic development in the mouse.	NLRP7 NLRP2	4.11e-06	2	71	2	22295082
Pubmed	Suppressing NLRP2 expression accelerates hepatic steatosis: A mechanism involving inflammation and oxidative stress.	NLRP7 NLRP2	4.11e-06	2	71	2	30454891
Pubmed	Mouse t haplotypes.	TBXT ITPR3	4.11e-06	2	71	2	3909941
Pubmed	NLRP2 inflammasome in dorsal root ganglion as a novel molecular platform that produces inflammatory pain hypersensitivity.	NLRP7 NLRP2	4.11e-06	2	71	2	31162334
Pubmed	T(16: 17)43H translocation as a tool in analysis of the proximal part of chromosome 17 (including T-t gene complex) of the mouse.	TBXT ITPR3	4.11e-06	2	71	2	7390155
Pubmed	Assignment of intrachain disulfide bonds and characterization of potential glycosylation sites of the type 1 recombinant human immunodeficiency virus envelope glycoprotein (gp120) expressed in Chinese hamster ovary cells.	MAN1A2 MAN1A1 GBA2	5.43e-06	17	71	3	2355006
Pubmed	The human cytoplasmic dynein interactome reveals novel activators of motility.	HYOU1 TRIO TCP1 POLR1C MCM3 CEP152 MCCC1 HERC2 PDZRN3 FAM83H	8.93e-06	853	71	10	28718761
Pubmed	Glycosylation inhibitors and neuraminidase enhance human immunodeficiency virus type 1 binding and neutralization by mannose-binding lectin.	MAN1A2 MAN1A1 GBA2	9.06e-06	20	71	3	12560567
Pubmed	Influence of N-linked glycans in V4-V5 region of human immunodeficiency virus type 1 glycoprotein gp160 on induction of a virus-neutralizing humoral response.	MAN1A2 MAN1A1 GBA2	1.22e-05	22	71	3	8673525
Pubmed	Effect of various glycosidase treatments on the resistance of the HIV-1 envelope to degradation.	MAN1A2 MAN1A1 GBA2	1.22e-05	22	71	3	9109416
Pubmed	Folding of the human immunodeficiency virus type 1 envelope glycoprotein in the endoplasmic reticulum.	MAN1A2 MAN1A1 GBA2	1.22e-05	22	71	3	11530211
Pubmed	Mosaic moles and non-familial biparental moles are not caused by mutations in NLRP7, NLRP2 or C6orf221.	NLRP7 NLRP2	1.23e-05	3	71	2	22909446
Pubmed	Loss of the Maternal Effect Gene Nlrp2 Alters the Transcriptome of Ovulated Mouse Oocytes and Impacts Expression of Histone Demethylase KDM1B.	NLRP7 NLRP2	1.23e-05	3	71	2	36976514
Pubmed	Apoptosis Signal-regulating Kinase 1 Silencing on Astroglial Inflammasomes in an Experimental Model of Ischemic Stroke.	NLRP7 NLRP2	1.23e-05	3	71	2	30172704
Pubmed	Characterization of a cDNA encoding a novel human Golgi alpha 1, 2-mannosidase (IC) involved in N-glycan biosynthesis.	MAN1A2 MAN1A1	1.23e-05	3	71	2	10915796
Pubmed	Gene mapping within the T/t complex of the mouse. I. t-Lethal genes are nonallelic.	TBXT ITPR3	1.23e-05	3	71	2	7074682
Pubmed	Maternal variants in NLRP and other maternal effect proteins are associated with multilocus imprinting disturbance in offspring.	NLRP7 NLRP2	1.23e-05	3	71	2	29574422
Pubmed	tctex-1: a candidate gene family for a mouse t complex sterility locus.	TCP1 TBXT	1.23e-05	3	71	2	2570638
Pubmed	Successful in vitro fertilization and generation of transgenics in Black and Tan Brachyury (BTBR) mice.	TBXT ITPR3	1.23e-05	3	71	2	27515175
Pubmed	Deletion mapping of the T/t complex: evidence for a second region of critical embryonic genes.	TCP1 TBXT	1.23e-05	3	71	2	6825938
Pubmed	eIF4A inhibition allows translational regulation of mRNAs encoding proteins involved in Alzheimer's disease.	MAPT EIF4A1	1.23e-05	3	71	2	20927385
Pubmed	Cyclic AMP-dependent protein kinase enhances SC35-promoted Tau exon 10 inclusion.	SRSF2 MAPT	1.23e-05	3	71	2	24037441
Pubmed	HLA-C expression in extravillous trophoblasts is determined by an ELF3-NLRP2/NLRP7 regulatory axis.	NLRP7 NLRP2	1.23e-05	3	71	2	39052836
Pubmed	Genetic analysis of mouse t haplotypes using mutations induced by ethylnitrosourea mutagenesis: the order of T and qk is inverted in t mutants.	TBXT ITPR3	1.23e-05	3	71	2	3197958
Pubmed	Characterization of a recombinant mouse T haplotype that expresses a dominant lethal maternal effect.	TBXT ITPR3	1.23e-05	3	71	2	6510705
Pubmed	Glycogen synthase kinase-3 plays a crucial role in tau exon 10 splicing and intranuclear distribution of SC35. Implications for Alzheimer's disease.	SRSF2 MAPT	1.23e-05	3	71	2	14602710
Pubmed	Minichromosome maintenance protein 2 and 3 promote osteosarcoma progression via DHX9 and predict poor patient prognosis.	MCM2 MCM3	1.23e-05	3	71	2	28460433
Pubmed	Uncoupling of Pyrin-only protein 2 (POP2)-mediated dual regulation of NF-κB and the inflammasome.	NLRP7 NLRP2	1.23e-05	3	71	2	21976665
Pubmed	Activation of NLRP2 in Triple-Negative Breast Cancer sensitizes chemotherapeutic therapy through facilitating hnRNPK function.	NLRP7 NLRP2	1.23e-05	3	71	2	37499769
Pubmed	Dyrk1A overexpression leads to increase of 3R-tau expression and cognitive deficits in Ts65Dn Down syndrome mice.	SRSF2 MAPT	1.23e-05	3	71	2	28377597
Pubmed	Isolation of a mouse Golgi mannosidase cDNA, a member of a gene family conserved from yeast to mammals.	MAN1A2 MAN1A1	1.23e-05	3	71	2	8144579
Pubmed	Combined lipase deficiency (cld): a lethal mutation on chromosome 17 of the mouse.	TBXT ITPR3	1.23e-05	3	71	2	6857276
Pubmed	Minichromosome Maintenance (MCM) Family as potential diagnostic and prognostic tumor markers for human gliomas.	MCM2 MCM3	1.23e-05	3	71	2	25046975
Pubmed	No evidence for mutations in NLRP7, NLRP2 or KHDC3L in women with unexplained recurrent pregnancy loss or infertility.	NLRP7 NLRP2	1.23e-05	3	71	2	25376457
Pubmed	HIV-1-Tat Protein Inhibits SC35-mediated Tau Exon 10 Inclusion through Up-regulation of DYRK1A Kinase.	SRSF2 MAPT	1.23e-05	3	71	2	26534959
Pubmed	Is there a Brachyury the Second? Analysis of a transgenic mutation involved in notochord maintenance in mice.	TBXT ITPR3	1.23e-05	3	71	2	7589801
Pubmed	Minichromosome maintenance proteins 2, 3 and 7 in medulloblastoma: overexpression and involvement in regulation of cell migration and invasion.	MCM2 MCM3	1.23e-05	3	71	2	20661220
Pubmed	Molecular cloning, chromosomal mapping and tissue-specific expression of a novel human alpha1,2-mannosidase gene involved in N-glycan maturation.	MAN1A2 MAN1A1	1.23e-05	3	71	2	9592125
Pubmed	NLRP2 and FAF1 deficiency blocks early embryogenesis in the mouse.	NLRP7 NLRP2	1.23e-05	3	71	2	28630100
Pubmed	Linkage relationships of markers on chromosome 17 of the house mouse.	TBXT ITPR3	1.23e-05	3	71	2	1225760
Pubmed	A diversified set of testicular cell proteins specified by genes within the mouse t complex.	TCP1 ITPR3	1.23e-05	3	71	2	6684996
Pubmed	Gene body hypomethylation of pyroptosis-related genes NLRP7, NLRP2, and NLRP3 facilitate non-invasive surveillance of hepatocellular carcinoma.	NLRP7 NLRP2	1.23e-05	3	71	2	37273114
Pubmed	Derivation of mutant t-haplotypes of the mouse by presumed duplication or deletion.	TBXT ITPR3	1.23e-05	3	71	2	924142
Pubmed	BAP1 regulation of the key adaptor protein NCoR1 is critical for γ-globin gene repression.	SRSF2 HYOU1 TCP1 KDM5A EIF4A1 POLR1C DIAPH1 MCM2 MCM3 MCCC1 INTS3 FAM83H	1.35e-05	1318	71	12	30463901
Pubmed	Role of asparagine-linked glycosylation in human immunodeficiency virus type 1 transmembrane envelope function.	MAN1A2 MAN1A1 GBA2	1.40e-05	23	71	3	1736542
Pubmed	Functional role of the glycan cluster of the human immunodeficiency virus type 1 transmembrane glycoprotein (gp41) ectodomain.	MAN1A2 MAN1A1 GBA2	1.40e-05	23	71	3	8093218
Pubmed	Glycosylation inhibitors block the expression of LAV/HTLV-III (HIV) glycoproteins.	MAN1A2 MAN1A1 GBA2	1.40e-05	23	71	3	3099781
Pubmed	Role of protein N-glycosylation in pathogenesis of human immunodeficiency virus type 1.	MAN1A2 MAN1A1 GBA2	1.40e-05	23	71	3	3264072
Pubmed	Mammalian BEX, WEX and GASP genes: coding and non-coding chimaerism sustained by gene conversion events.	TCEAL7 TCEAL4 TCEAL2	1.60e-05	24	71	3	16221301
Pubmed	Effect of N-(3-phenyl-2-propenyl)-1-deoxynojirimycin on the lectin binding to HIV-1 glycoproteins.	MAN1A2 MAN1A1 GBA2	1.82e-05	25	71	3	2283726
Pubmed	Site-specific N-glycosylation and oligosaccharide structures of recombinant HIV-1 gp120 derived from a baculovirus expression system.	MAN1A2 MAN1A1 GBA2	2.05e-05	26	71	3	8218172
Pubmed	Acentriolar mitosis activates a p53-dependent apoptosis pathway in the mouse embryo.	TUBG2 TBXT CEP152	2.30e-05	27	71	3	24706806
Pubmed	CEP63 deficiency promotes p53-dependent microcephaly and reveals a role for the centrosome in meiotic recombination.	TUBG2 SUN1 CEP152	2.30e-05	27	71	3	26158450
Pubmed	Amyloid-β peptide alteration of tau exon-10 splicing via the GSK3β-SC35 pathway.	SRSF2 MAPT	2.46e-05	4	71	2	20615469
Pubmed	Pleiotropic action of the murine quaking locus: structure of the qkv allele.	TBXT ITPR3	2.46e-05	4	71	2	1665374
Pubmed	Stabilization of dynamic microtubules by mDia1 drives Tau-dependent Aβ1-42 synaptotoxicity.	MAPT DIAPH1	2.46e-05	4	71	2	28877993
Pubmed	Nod2 improves barrier function of intestinal epithelial cells via enhancement of TLR responses.	NLRP7 NLRP2	2.46e-05	4	71	2	22750073
Pubmed	Genetic and molecular analysis of the proximal region of the mouse t-complex using new molecular probes and partial t-haplotypes.	TCP1 TBXT	2.46e-05	4	71	2	2076813
Pubmed	Interaction of hRad51 and hRad52 with MCM complex: a cross-talk between recombination and replication proteins.	MCM2 MCM3	2.46e-05	4	71	2	15766559
Pubmed	HERC2 Interacts with Claspin and regulates DNA origin firing and replication fork progression.	MCM2 HERC2	2.46e-05	4	71	2	21775519
Pubmed	The FHA and BRCT domains recognize ADP-ribosylation during DNA damage response.	NLRP7 NLRP2	2.46e-05	4	71	2	23964092
Pubmed	A novel mouse chromosome 17 hybrid sterility locus: implications for the origin of t haplotypes.	TCP1 TBXT	4.09e-05	5	71	2	1936961
Pubmed	Embryonic expression of the myelin basic protein gene: identification of a promoter region that targets transgene expression to pioneer neurons.	RELN MAPT	4.09e-05	5	71	2	9736652
Pubmed	Incremental genetic perturbations to MCM2-7 expression and subcellular distribution reveal exquisite sensitivity of mice to DNA replication stress.	MCM2 MCM3	4.09e-05	5	71	2	20838603
Pubmed	Analysis of Ellis van Creveld syndrome gene products: implications for cardiovascular development and disease.	EVC2 TUBG2	4.09e-05	5	71	2	19251731
Pubmed	Fas-associated factor 1 is a negative regulator of PYRIN-containing Apaf-1-like protein 1.	NLRP7 NLRP2	4.09e-05	5	71	2	17046979
Pubmed	The interaction between ATRIP and MCM complex is essential for ATRIP chromatin loading and its phosphorylation in mantle cell lymphoma cells.	MCM2 MCM3	4.09e-05	5	71	2	29442041
Pubmed	ATR-mediated phosphorylation of FANCI regulates dormant origin firing in response to replication stress.	MCM2 MCM3	4.09e-05	5	71	2	25843623
Pubmed	Identifying biological pathways that underlie primordial short stature using network analysis.	SRSF2 HYOU1 TCP1 EIF4A1 SUN1 MCM2 MCM3 HERC2 FAM83H ITPR3	4.25e-05	1024	71	10	24711643
Pubmed	Chr21 protein-protein interactions: enrichment in proteins involved in intellectual disability, autism, and late-onset Alzheimer's disease.	RELN MAN1A2 PDE9A TRIO TUBG2 KDM5A EIF4A1 POLR1C HERC2 DCLK1 ADD3	5.62e-05	1285	71	11	35914814
Pubmed	Role of oligosaccharides in the processing and maturation of envelope glycoproteins of human immunodeficiency virus type 1.	MAN1A2 MAN1A1 GBA2	6.03e-05	37	71	3	2541446
Pubmed	Biosynthesis and processing of human immunodeficiency virus type 1 envelope glycoproteins: effects of monensin on glycosylation and transport.	MAN1A2 MAN1A1 GBA2	6.03e-05	37	71	3	2542563
Pubmed	Pairwise interactions of the six human MCM protein subunits.	MCM2 MCM3	6.13e-05	6	71	2	15236977
Pubmed	Expression Analyses of Cep152, a Responsible Gene Product for Autosomal Recessive Primary Microcephaly, during Mouse Brain Development.	TUBG2 CEP152	6.13e-05	6	71	2	35259752
Pubmed	Highly stable loading of Mcm proteins onto chromatin in living cells requires replication to unload.	MCM2 MCM3	6.13e-05	6	71	2	21220507
Pubmed	Minichromosome maintenance proteins are direct targets of the ATM and ATR checkpoint kinases.	MCM2 MCM3	6.13e-05	6	71	2	15210935
Pubmed	Basal level of FANCD2 monoubiquitination is required for the maintenance of a sufficient number of licensed-replication origins to fire at a normal rate.	MCM2 MCM3	6.13e-05	6	71	2	24658369
Pubmed	Functional screening of five PYPAF family members identifies PYPAF5 as a novel regulator of NF-kappaB and caspase-1.	NLRP7 NLRP2	6.13e-05	6	71	2	12387869
Pubmed	Evolution of mouse chromosome 17 and the origin of inversions associated with t haplotypes.	TCP1 TBXT	6.13e-05	6	71	2	2717616
Pubmed	Multiple origins of Cajal-Retzius cells at the borders of the developing pallium.	RELN MAPT	6.13e-05	6	71	2	16041369
Pubmed	The eukaryotic Mcm2-7 replicative helicase.	MCM2 MCM3	6.13e-05	6	71	2	22918583
Pubmed	In vivo interaction of human MCM heterohexameric complexes with chromatin. Possible involvement of ATP.	MCM2 MCM3	6.13e-05	6	71	2	9099751
Interaction	CCT5 interactions	SRSF2 HYOU1 TCP1 TUBG2 MAPT EIF4A1 DNAI2 MCM2 TNK2 KLHL8	1.47e-05	525	71	10	int:CCT5
Interaction	ATRIP interactions	POLR1C MCM2 MCM3 HERC2 INTS3	2.13e-05	95	71	5	int:ATRIP
Interaction	CLU interactions	SETX MAN1A2 MAN1A1 HYOU1 MAPT POLR1C MCM2	2.47e-05	245	71	7	int:CLU
Interaction	STIP1 interactions	EVC2 SRSF2 HYOU1 TCP1 MAPT DNAI2 DIAPH1 MCM2 MCM3 WDFY4 ADD3 FAM83H LRRC9	4.33e-05	1006	71	13	int:STIP1
Interaction	CCT3 interactions	EPS15 TCP1 TUBG2 MAPT POLR1C DNAI2 MCM2 TNK2 KLHL8 WDFY4	4.83e-05	604	71	10	int:CCT3
Cytoband	6q22	MAN1A1 MFSD4B	6.56e-05	8	71	2	6q22
Cytoband	6q15	CFAP206 C6orf163	1.07e-03	31	71	2	6q15
GeneFamily	Transcription elongation factor A like family	TCEAL7 TCEAL4 TCEAL2	1.55e-06	9	49	3	1216
GeneFamily	Mannosidases alpha class 1	MAN1A2 MAN1A1	4.30e-05	4	49	2	1193
GeneFamily	MCM family	MCM2 MCM3	2.56e-04	9	49	2	1085
GeneFamily	AT-rich interaction domain containing	ARID3A KDM5A	7.39e-04	15	49	2	418
GeneFamily	NLR family	NLRP7 NLRP2	2.07e-03	25	49	2	666
GeneFamily	Pyrin domain containing\|Pyrin and HIN domain family	NLRP7 NLRP2	2.07e-03	25	49	2	994
GeneFamily	Transient receptor potential cation channels	TRPM3 MCOLN2	2.60e-03	28	49	2	249
ToppCell	droplet-Lung-18m-Hematologic-lymphocytic-plasma_cell\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	RELN MAN1A1 ARID3A TUBG2 LRRC2 LAX1 JHY	8.22e-09	164	71	7	b92e7c91910d518627376166c6ea9ed333b3d07e
ToppCell	droplet-Lung-18m-Hematologic-lymphocytic-plasma_cell-plasma_cell\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	RELN MAN1A1 ARID3A TUBG2 LRRC2 LAX1 JHY	8.22e-09	164	71	7	a1e43c6b3e2553f5604100db6e92bf244b70c36d
ToppCell	droplet-Lung-nan-18m-Lymphocytic-plasma_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	RELN MAN1A1 TUBG2 LRRC2 LAX1 JHY	2.43e-07	163	71	6	5efecdd8a069a822bc9d35b407092925a865e629
ToppCell	droplet-Lung-nan-18m-Lymphocytic-Plasma_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	RELN MAN1A1 TUBG2 LRRC2 LAX1 JHY	2.43e-07	163	71	6	0d94a427f86e62aba12c397c6d7b8cd297f3a0e5
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast-proliferative_fibroblast\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	TCEAL7 ZFHX4 TCEAL4 LAMA2 SLC28A3 DCLK1	3.95e-07	177	71	6	b872ee91e01265b101b81bd304cf6b95d5419e68
ToppCell	moderate-Myeloid-pDC\|moderate / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls	ARID3A NLRP7 CCDC183 WDFY4 PDZRN3 MCOLN2	4.35e-07	180	71	6	a0751ad5e42a21cb107d900abfa9ee967a0069fc
ToppCell	PND10-Immune-Immune_Lymphocytic_T/NK-Lymphocytic_B-B-B_prolif\|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	MAN1A1 ARID3A MCM2 MCM3 USP1 MCOLN2	4.80e-07	183	71	6	956ff95aef9c5521b6a3ba7ac6df0aad242c1c35
ToppCell	Biopsy_Control_(H.)-Mesenchymal-Mesothelial_cells\|Biopsy_Control_(H.) / Sample group, Lineage and Cell type	TCEAL7 ZFHX4 TRPM3 SLC28A3 PLOD2 DCLK1	7.83e-07	199	71	6	ca970114b5aef4518ce580897a62ac88688b2671
ToppCell	facs-Marrow-B-cells-24m-Lymphocytic-early_pro-B_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TCEAL7 PDE9A ZFHX4 GUCY2F DNAI2	3.44e-06	144	71	5	1d05aa08603cba28c0c6511767e434c1f592a3aa
ToppCell	facs-Marrow-B-cells-24m-Lymphocytic-early_pro_B_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TCEAL7 PDE9A ZFHX4 GUCY2F DNAI2	3.44e-06	144	71	5	d3f6f5da56794367ee3776bfd3a9dcf893efe0f0
ToppCell	droplet-Thymus-nan-21m-Myeloid-Plasma_cells_and_B_cells\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	RELN EVC2 MAN1A1 ARID3A ABHD3	6.68e-06	165	71	5	21a82a975f550080b6674750b06212205cd16742
ToppCell	356C-Fibroblasts-Fibroblast-D\|356C / Donor, Lineage, Cell class and subclass (all cells)	RELN EVC2 ZFHX4 LAMA2 LRRC2	6.88e-06	166	71	5	7286a37b2827f3747469ffd0d76cbe81116db7ee
ToppCell	356C-Fibroblasts-Fibroblast-D-\|356C / Donor, Lineage, Cell class and subclass (all cells)	RELN EVC2 ZFHX4 LAMA2 LRRC2	6.88e-06	166	71	5	7c2eee0a4f45795a956acf936b85bdb35f1b1624
ToppCell	facs-Brain_Non-Myeloid-Striatum-3m-Mesenchymal-Ependyma\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CAPSL CFAP206 SLC28A3 CFAP70 JHY	9.40e-06	177	71	5	ae01c19403a09f7ba5e4beafdfcd1b8eebdadcb7
ToppCell	facs-Brain_Non-Myeloid-Striatum-3m-Mesenchymal-ependymal_cell\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CAPSL CFAP206 SLC28A3 CFAP70 JHY	9.40e-06	177	71	5	bd3d07bdef6e903995d4bbfb6ff3a5e1d9fb70cc
ToppCell	NS-moderate-d_16-33-Myeloid-pDC\|d_16-33 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	ARID3A NLRP7 CCDC183 WDFY4 MCOLN2	1.02e-05	180	71	5	144818e69613296cde43f29cb8c20899c670b319
ToppCell	21-Trachea-Epithelial-Multiciliated_precursor\|Trachea / Age, Tissue, Lineage and Cell class	CAPSL CFAP206 CEP152 PLOD2 JHY	1.08e-05	182	71	5	6e35892fa959ee31591850ded8f1088195ddeb01
ToppCell	normal_Lung-B_lymphocytes-GrB-secreting_B_cells\|normal_Lung / Location, Cell class and cell subclass	ARID3A HYOU1 NLRP7 CCDC183 WDFY4	1.10e-05	183	71	5	c930b957d16f9b0904b6c424acd914532e5cc137
ToppCell	droplet-Marrow-nan-3m-Lymphocytic-late_pro-B_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	EVC2 MAN1A1 HYOU1 LAX1 JHY	1.13e-05	184	71	5	42cadfdb5d29a50bd7e901ddd14d42b39e8474f0
ToppCell	E18.5-Epithelial-Epithelial_Airway-Ciliated/Deuterosomal-Ciliated\|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	CAPSL DNAI2 CFAP206 CFAP70 JHY	1.13e-05	184	71	5	797b6a6d6f6aafae98f75ca8bffe8263f8d3ff9b
ToppCell	E18.5-Epithelial-Epithelial_Airway-Ciliated/Deuterosomal-Ciliated-Ciliated_mature\|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	CAPSL DNAI2 CFAP206 CFAP70 JHY	1.13e-05	184	71	5	77d5b60a20b277f589b18f7a131142a7ef2dac17
ToppCell	5'-Airway_Nasal-Immune_Myeloid-Dendritic-plasmacytoid_dendritic_cell\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	ARID3A NLRP7 CCDC183 WDFY4 MCOLN2	1.19e-05	186	71	5	0096a61b1841784c913752b4f3639200446cc02c
ToppCell	5'-Airway_Nasal-Immune_Myeloid-Dendritic-plasmacytoid_dendritic_cell-Plasmacytoid_DCs-Plasmacytoid_DCs_L.1.5.1.0\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	ARID3A NLRP7 CCDC183 WDFY4 MCOLN2	1.19e-05	186	71	5	6345777847960c71a2ba3ce5a49c72c34ebd0e73
ToppCell	5'-Airway_Nasal-Immune_Myeloid-Dendritic-plasmacytoid_dendritic_cell-Plasmacytoid_DCs\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	ARID3A NLRP7 CCDC183 WDFY4 MCOLN2	1.19e-05	186	71	5	9e159ad7289dcae2ec7ce655df746f46801b81d3
ToppCell	facs-Lung-EPCAM-3m-Epithelial-Ciliated_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CAPSL DNAI2 CFAP206 CFAP70 JHY	1.23e-05	187	71	5	04dba2ed09ee4180830bdf0191921696697ea234
ToppCell	P15-Epithelial-airway_epithelial_cell-club_cell\|P15 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	CAPSL DNAI2 CFAP206 CFAP70 JHY	1.23e-05	187	71	5	a70aaae32426e9ddb1cbfbd0e0db24ccc96b9f40
ToppCell	facs-Lung-EPCAM-3m-Epithelial-ciliated_columnar_cell_of_tracheobronchial_tree\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CAPSL DNAI2 CFAP206 CFAP70 JHY	1.23e-05	187	71	5	805dafe22f835ece4dd091d8030d0a63b52a48dd
ToppCell	P15-Epithelial-airway_epithelial_cell\|P15 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	CAPSL DNAI2 CFAP206 CFAP70 JHY	1.26e-05	188	71	5	e3e71c0f2e374330620cb4d27638953ffa9f5298
ToppCell	facs-Lung-24m-Epithelial-airway_epithelial-lung_ciliated_cell\|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	CAPSL DNAI2 ABHD3 CFAP206 CFAP70	1.29e-05	189	71	5	1c28ad1263891d963e483b6847d8e89cc1b2d07e
ToppCell	facs-Lung-24m-Epithelial-airway_epithelial-lung_ciliated_cell-ciliated_cell\|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	CAPSL DNAI2 ABHD3 CFAP206 CFAP70	1.29e-05	189	71	5	00b20c2ed7876486c8e42e3a5b13023f44987a34
ToppCell	facs-Lung-nan-3m-Epithelial-Ciliated_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TRPM3 CAPSL DNAI2 CFAP206 CFAP70	1.32e-05	190	71	5	e243b5fbb17b9ec3cc90bbe970c1d30b0fd1c2e1
ToppCell	ILEUM-non-inflamed-(7)_Endothelial_cell-(7)_Lymphatics\|(7)_Endothelial_cell / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)	EPS15 RELN EVC2 MAN1A1 ADD3	1.32e-05	190	71	5	9ce301841ce9486701fa28eb2a9929e35d476878
ToppCell	facs-Lung-nan-3m-Epithelial-ciliated_columnar_cell_of_tracheobronchial_tree\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TRPM3 CAPSL DNAI2 CFAP206 CFAP70	1.32e-05	190	71	5	fe844559b95832845d2e8d3ab4b57e3d558bc372
ToppCell	PBMC_fresh-frozen-Mild-Moderate_progression_d02_child-Lymphocytic-Lymphocytic_B-B_cell-B_c02-MS4A1-CD27\|Mild-Moderate_progression_d02_child / Compartment, severity and other cell annotations on 10x 3' data (130k)	EPS15 TRIO POLR1C MFSD4B WDFY4	1.43e-05	193	71	5	08696a99309f5b088692ddac8cca35413b5e810d
ToppCell	Tracheal-NucSeq-Stromal-Peri/Epineurial_-NAF_endoneurial\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	ZFHX4 TUBG2 LAMA2 PDZRN3 DCLK1	1.43e-05	193	71	5	549a0b750c860b615aff767ad04c9a9d20f802f0
ToppCell	Control_saline-Epithelial_airway-airway_epithelial-Ciliated\|Control_saline / Treatment groups by lineage, cell group, cell type	CAPSL DNAI2 CFAP206 CFAP70 LRRC9	1.50e-05	195	71	5	60067b5359174f0d1a8b5748bfc0690762e9e740
ToppCell	IPF-Stromal-Myofibroblast\|World / Disease state, Lineage and Cell class	TCEAL7 LAMA2 PLOD2 PDZRN3 DCLK1	1.54e-05	196	71	5	7fc9894ceb79dab9f0495acc84e2d6d0d1c69bb7
ToppCell	Biopsy_Other_PF-Mesenchymal-Mesothelial_cells\|Biopsy_Other_PF / Sample group, Lineage and Cell type	ZFHX4 TRPM3 TCEAL2 SLC28A3 PLOD2	1.61e-05	198	71	5	86736f01e61bf4961f060b24ee1f1f48340737dd
ToppCell	MS-Multiple_Sclerosis-Myeloid-pDC\|Multiple_Sclerosis / Disease, condition lineage and cell class	ARID3A NLRP7 CCDC183 WDFY4 MCOLN2	1.65e-05	199	71	5	c10c8c9322cad4996e4aa11a8680e3d781644ace
ToppCell	Bronchial-10x5prime-Epithelial-Epi_airway_ciliated-Deuterosomal\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	CAPSL DNAI2 CFAP206 CFAP70 LRRC9	1.65e-05	199	71	5	92778939e9d06599c7d06cfd8f4362b97ed0606b
ToppCell	CV-Moderate-2\|CV / Virus stimulation, Condition and Cluster	SRSF2 TCP1 EIF4A1 MCM2 MCM3	1.65e-05	199	71	5	2d98424a5247e87f98095c11fb945289092a9d75
ToppCell	CD8+_Memory_T_cell-CV-2\|CD8+_Memory_T_cell / cell class, Virus stimulation and cluster	SRSF2 TCP1 EIF4A1 MCM2 MCM3	1.65e-05	199	71	5	1e33d8e2e0d6a54ef6e2e13f986e19fd209275a8
ToppCell	CV-Moderate-2\|Moderate / Virus stimulation, Condition and Cluster	SRSF2 TCP1 EIF4A1 MCM2 MCM3	1.65e-05	199	71	5	70d6f2a328eec4cb2cecb7cd85859fba9e15c9c8
ToppCell	CV-Mild-2\|Mild / Virus stimulation, Condition and Cluster	SRSF2 TCP1 EIF4A1 MCM2 MCM3	1.65e-05	199	71	5	d88cc07053a852e6c468538a0a851ffa09f97a0d
ToppCell	Fetal_brain-fetalBrain_Zhong_nature-GW09-Stem_cells-Stem_cells\|GW09 / Sample Type, Dataset, Time_group, and Cell type.	SRSF2 ZFHX4 ABHD3 MCM2 MCM3	1.69e-05	200	71	5	c00cc0b91baa37828895d9d6b8acbc6aa503215a
ToppCell	Fetal_brain-fetalBrain_Zhong_nature-GW09-Stem_cells\|GW09 / Sample Type, Dataset, Time_group, and Cell type.	SRSF2 ZFHX4 ABHD3 MCM2 MCM3	1.69e-05	200	71	5	9e1b62a703fb7d413ce580448a1df5127c28e8a7
ToppCell	Biopsy_Control_(H.)-Mesenchymal-PLIN2+_Fibroblasts\|Biopsy_Control_(H.) / Sample group, Lineage and Cell type	ZFHX4 LAMA2 LRRC2 PDZRN3 DCLK1	1.69e-05	200	71	5	cdaf462b1db29dab61038eeab5ddd3eef3386763
ToppCell	Control-PLT_5\|World / Disease Group and Platelet Clusters	MAPT CFAP70 POTEJ PADI1	4.93e-05	126	71	4	4ba753c4e83eb1d41964edfa22135e047f06c481
ToppCell	368C-Myeloid-Macrophage-FABP4+_Macrophage\|Macrophage / Donor, Lineage, Cell class and subclass (all cells)	MAN1A1 CAPSL CFAP206 LAX1	8.73e-05	146	71	4	5b2608b56204dda9a773988f42ff00a9fa743a39
ToppCell	PND01-03-samps-Epithelial-Epithelial-non_alveolar\|PND01-03-samps / Age Group, Lineage, Cell class and subclass	CAPSL DNAI2 CFAP206 CFAP70	1.05e-04	153	71	4	fc0d2d50aa3b6b2772bbf3626c9df5c5e8d7d11e
ToppCell	PND01-03-samps-Epithelial-Epithelial-non_alveolar-Ciliated_cell_of_lung_parenchyma\|PND01-03-samps / Age Group, Lineage, Cell class and subclass	CAPSL DNAI2 CFAP206 CFAP70	1.05e-04	153	71	4	2482247d9c39c7b99bb45fb9153442f64fd6012f
ToppCell	primary_visual_cortex-Neuronal-glutamatergic_neuron-L2/3_IT-L2/3_IT_VISp_Adamts2\|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	EVC2 ZFHX4 CAPSL PDZRN3	1.13e-04	156	71	4	2cd007b423c2395c5ce331902e7f27c805755eb3
ToppCell	Children_(3_yrs)-Mesenchymal-chondrocyte\|Children_(3_yrs) / Lineage, Cell type, age group and donor	TCEAL7 ZFHX4 LAMA2 PDZRN3	1.16e-04	157	71	4	f147e24f2ece82e1c54750868954d09b3c461804
ToppCell	3'-GW_trimst-2-SmallIntestine-Mesenchymal-fibroblastic-mLTo\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	MAPT CFAP206 CFAP70 DCLK1	1.16e-04	157	71	4	c779a53b2c67d566f5d417e753cd17196a6bfd1c
ToppCell	severe_COVID-19-pDC\|severe_COVID-19 / disease group, cell group and cell class (v2)	NLRP7 CCDC183 NLRP2 MCOLN2	1.21e-04	159	71	4	ea5088d27e42b8850455764d53b757ea8d8f14bc
ToppCell	PND28-Immune-Immune_Lymphocytic_T/NK-Lymphocytic_ILC-NK-NK-NK_prolif\|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	MCM2 MCM3 CEP152 USP1	1.24e-04	160	71	4	5cc1b75e3c20d83112b3aa2f3c749a6c73910a2d
ToppCell	E16.5-Epithelial-Epithelial_Airway-Ciliated/Deuterosomal-Deuterosomal-Deuterosomal_G2M\|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	CAPSL DNAI2 CFAP206 CFAP70	1.37e-04	164	71	4	d9531848105d606adedde65426177cf851140e31
ToppCell	Ciliated_cells-B-Cryobiopsy_01\|World / lung cells shred on cell class, cell subclass, sample id	CAPSL DNAI2 CFAP206 CFAP70	1.37e-04	164	71	4	0e9961acbb1d6c0089e6805ba6756736fa4d8bed
ToppCell	NS-critical-d_07-13-Myeloid-pDC\|d_07-13 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	NLRP7 CCDC183 WDFY4 MCOLN2	1.40e-04	165	71	4	17d5c4a111d9b5400780bc5e7b93ce2f5d69ceb7
ToppCell	facs-Lung-24m-Hematologic-lymphocytic-plasma_cell-plasma_cell\|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	MAN1A1 TBXT LAX1 MCOLN2	1.43e-04	166	71	4	139bf49eb3624d9eec7e8a2cb33d69716d63a7c5
ToppCell	facs-Lung-24m-Hematologic-lymphocytic-plasma_cell\|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	MAN1A1 TBXT LAX1 MCOLN2	1.43e-04	166	71	4	85f59c3cc7db8863ec0044f1fcc14580834f830b
ToppCell	facs-Lung-18m-Hematologic-lymphocytic-plasma_cell-plasma_cell\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	MAN1A1 TUBG2 LAX1 MCOLN2	1.47e-04	167	71	4	8ec7a98b542b134f48df8fbec351693cc5cfe55c
ToppCell	PND03-Immune-Immune_Lymphocytic_T/NK-Lymphocytic_ILC-NK-ILC-ILC_prolif\|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	MCM2 MCM3 USP1 LAX1	1.47e-04	167	71	4	53e32d6687a07f486141df9f4ab998af4c03a507
ToppCell	facs-Lung-18m-Hematologic-lymphocytic-plasma_cell\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	MAN1A1 TUBG2 LAX1 MCOLN2	1.47e-04	167	71	4	a9f28c4649ce344ae3ba3a3acb58da9c7efad901
ToppCell	Adult-Mesenchymal-chondrocyte-D175\|Adult / Lineage, Cell type, age group and donor	ZFHX4 TRPM3 LAMA2 DCLK1	1.50e-04	168	71	4	14071b961c9bdb54a8259b12a88237b802cbde36
ToppCell	facs-Lung-EPCAM-18m-Lymphocytic-plasma_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MAN1A1 TUBG2 LAX1 MCOLN2	1.53e-04	169	71	4	e348d9877a1bcad4f33dd7b2ce6cb0049583c4d2
ToppCell	TCGA-Liver-Primary_Tumor-Hepatocellular_Carcinoma-Hepatocellular_Carcinoma-4\|TCGA-Liver / Sample_Type by Project: Shred V9	ARID3A PDE9A ABHD3 C6orf163	1.53e-04	169	71	4	0a3ba6b5d6cff9d3d7f56046063cfc3a37ae1156
ToppCell	facs-Lung-EPCAM-18m-Lymphocytic-Plasma_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MAN1A1 TUBG2 LAX1 MCOLN2	1.53e-04	169	71	4	3167ca0c826244280e0e07d1e02656cf5e4e75a5
ToppCell	Bronchial_Brush-Immune-B_cells\|Immune / Tissue, Lineage and Cell class of Lung Cells from 10X	ARID3A SUN1 LAX1 ADD3	1.57e-04	170	71	4	53e9372cb06a2dc5c8ecb3f9af42f3c23da96431
ToppCell	3'-Broncho-tracheal-Immune_Myeloid-Dendritic-plasmacytoid_dendritic_cell-Plasmacytoid_DCs-Plasmacytoid_DCs_L.1.5.1.1\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	ARID3A NLRP7 WDFY4 MCOLN2	1.60e-04	171	71	4	4fd2c7977c512c51507f055fc74b111c0228ed8b
ToppCell	COVID-19_Convalescent-cDC\|COVID-19_Convalescent / Disease condition and Cell class	MCM3 NLRP2 JHY MCOLN2	1.60e-04	171	71	4	9ccaa9f1629818b0f63a5d930ee78c01e04cd98d
ToppCell	TCGA-Brain-Primary_Tumor-Low_Grade_Glioma-Astrocytoma-10\|TCGA-Brain / Sample_Type by Project: Shred V9	WDFY4 PADI1 JHY LRRC9	1.60e-04	171	71	4	74be8d3bf6b99e2d734635a8b1a7c41e8c596959
ToppCell	COVID-19_Convalescent-cDC-\|COVID-19_Convalescent / Disease condition and Cell class	MCM3 NLRP2 JHY MCOLN2	1.60e-04	171	71	4	fb5fae8b3adafcbb7c5618d887966b418355ed4d
ToppCell	facs-Lung-Endomucin-3m-Endothelial-Lymphatic_endothelial_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	RELN TUBG2 LAX1 JHY	1.64e-04	172	71	4	b3c4adccc34bb9e4e78e40f4e2e23736c347cc75
ToppCell	3'-Broncho-tracheal-Mesenchymal-Fibroblastic-fibroblastic_type_1-Adventitial_fibroblasts-\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	TRIO LAMA2 DCLK1 ADD3	1.64e-04	172	71	4	e37c0b5b547a7345179ab258dd2141fec7064c17
ToppCell	facs-Heart-RV-18m-Lymphocytic-B_cell\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	RELN ARID3A MCM2 LAX1	1.64e-04	172	71	4	2dcc9d67d6ecc35940eabbc8ed528f5f884f6976
ToppCell	facs-Lung-Endomucin-3m-Endothelial-endothelial_cell_of_lymphatic_vessel\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	RELN TUBG2 LAX1 JHY	1.64e-04	172	71	4	2f1673fcb2356684d60871debb0f159aec553a1c
ToppCell	facs-Heart-RV-18m-Lymphocytic-B_cell\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	RELN ARID3A MCM2 LAX1	1.64e-04	172	71	4	64d2edbd8e2640b76225597883b1a524e6b1dd3b
ToppCell	facs-Heart-RV-18m-Lymphocytic\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	RELN ARID3A MCM2 LAX1	1.64e-04	172	71	4	d061ea21bee179df5a525842e9a48621a8e1461b
ToppCell	PND07-28-samps-Epithelial-Epithelial-non_alveolar-Ciliated_cell_of_lung_parenchyma\|PND07-28-samps / Age Group, Lineage, Cell class and subclass	CAPSL DNAI2 CFAP206 CFAP70	1.72e-04	174	71	4	f41d05a3703d7092bd3c4a97c15ae13069aaa4ad
ToppCell	facs-Marrow-B-cells-18m-Lymphocytic-early_pro-B_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SLC30A5 PDE9A TUBG2 CAPSL	1.72e-04	174	71	4	268be5e7d2a18b866770b7cdb966c3958c7e6534
ToppCell	PND14-Immune-Immune_Myeloid-DC-cDC1-cDC1_prolif\|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	ARID3A MCM2 WDFY4 CCDC93	1.72e-04	174	71	4	09b091e24317c3f7bac043f04762a533e30793de
ToppCell	facs-Marrow-B-cells-18m-Lymphocytic-early_pro_B_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SLC30A5 PDE9A TUBG2 CAPSL	1.72e-04	174	71	4	4cdf2eedc28d88d18241ee390092426fdf849e79
ToppCell	normal_Lymph_Node-Myeloid_cells-pDCs\|Myeloid_cells / Location, Cell class and cell subclass	ARID3A HYOU1 SUN1 MCOLN2	1.72e-04	174	71	4	2274648b80dd74f3c948a779bba3391095964c34
ToppCell	BAL-Control-Myeloid-cDC-cDC-cDC_11\|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)	FSIP2 TRPM3 WDFY4 MCOLN2	1.72e-04	174	71	4	c8cec89369cf3896c5626e447051e76a142cb6df
ToppCell	systemic_lupus_erythematosus-managed-Lymphocytic_B-plasmablast-male\|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex	MAN1A1 NLRP7 MCM2 CEP152	1.75e-04	175	71	4	89bf89466191da14896ed8928027f5b911436c22
ToppCell	BAL-Control-cDC_11\|Control / Compartment, Disease Groups and Clusters	FSIP2 EVC2 TRPM3 WDFY4	1.75e-04	175	71	4	daf014e15a354956e9149c83fd89d0af0d07eb00
ToppCell	PND07-28-samps-Epithelial-Epithelial-non_alveolar\|PND07-28-samps / Age Group, Lineage, Cell class and subclass	CAPSL DNAI2 CFAP206 CFAP70	1.75e-04	175	71	4	c01a15b2084da4a18f8ff3623f44eb9dfe499f10
ToppCell	facs-Marrow-B-cells-18m-Hematologic-Unknown_Progenitor\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	RELN EVC2 TUBG2 LAX1	1.79e-04	176	71	4	5f9ae5eb45603ed0422a3a993ecdbe2ce05d6e45
ToppCell	normal_Lymph_Node-Myeloid_cells-pDCs\|normal_Lymph_Node / Location, Cell class and cell subclass	ARID3A HYOU1 SUN1 MCOLN2	1.79e-04	176	71	4	476794ef75ce5ab732d78cfeb4944e2f841e3e92
ToppCell	droplet-Marrow-BM-1m-Lymphocytic-late_pro-B_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	HYOU1 MAPT LAX1 ITPR3	1.79e-04	176	71	4	2e9073166da4d9fae70ba4f3fdcad35523caf7cd
ToppCell	droplet-Lung-LUNG-1m-Lymphocytic-plasma_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MAN1A1 ARID3A HYOU1 LAX1	1.83e-04	177	71	4	c6812679aa6522d03bd29144e71c5fae6a92325e
ToppCell	droplet-Lung-LUNG-1m-Lymphocytic-Plasma_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MAN1A1 ARID3A HYOU1 LAX1	1.83e-04	177	71	4	ff97398d2adb83063b7c53a264bfae86ea7ea304
ToppCell	3'-Broncho-tracheal-Immune_Myeloid-Dendritic-plasmacytoid_dendritic_cell-Plasmacytoid_DCs\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	ARID3A NLRP7 WDFY4 MCOLN2	1.83e-04	177	71	4	8887ff6341eb070bdaa890cc2cd7745f0cf1b0af
ToppCell	3'-Broncho-tracheal-Immune_Myeloid-Dendritic-plasmacytoid_dendritic_cell\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	ARID3A NLRP7 WDFY4 MCOLN2	1.83e-04	177	71	4	507f06d31ab773099c9431b6f433899dc97b5566
ToppCell	3'-Broncho-tracheal-Immune_Myeloid-Dendritic-plasmacytoid_dendritic_cell-Plasmacytoid_DCs-Plasmacytoid_DCs_L.1.5.1.0\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	ARID3A NLRP7 WDFY4 MCOLN2	1.91e-04	179	71	4	c9f45cfea0ceb0cdc31bcfd123aeab69aeb35c35
ToppCell	IIH-matDC\|IIH / Condition, Cell_class and T cell subcluster	TCEAL7 GUCY2F PLOD2 DCLK1	1.91e-04	179	71	4	5999c85ce3bab5309ff1ed154be7e32b037750b1
ToppCell	IIH-matDC-\|IIH / Condition, Cell_class and T cell subcluster	TCEAL7 GUCY2F PLOD2 DCLK1	1.91e-04	179	71	4	46074b2781ed79e2979428b3ec81504621d3903c
ToppCell	facs-Brain_Non-Myeloid-Cortex_-18m-Mesenchymal-ependymal_cell\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CAPSL CFAP206 CFAP70 JHY	1.95e-04	180	71	4	2b8447c3487b0f29e1d5ded980fe5a96dffd7a9e
ToppCell	facs-Brain_Non-Myeloid-Cortex_-18m-Mesenchymal-Ependyma\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CAPSL CFAP206 CFAP70 JHY	1.95e-04	180	71	4	babbdc9d3127c62c8db1ce33e0be61669e004893
Computational	Neighborhood of PRKDC	ARID3A TCP1 DIAPH1 MCM2 MCM3 USP1	5.00e-05	191	38	6	MORF_PRKDC
Computational	Neighborhood of MLH1	TCP1 MCM3 USP1	4.25e-04	42	38	3	GNF2_MLH1
Computational	Neighborhood of RRM1	TCP1 MCM2 MCM3 USP1	4.40e-04	102	38	4	MORF_RRM1
Computational	Neighborhood of APEX1	SRSF2 TCP1 EIF4A1 MCM3	6.71e-04	114	38	4	GCM_APEX1
Computational	Neighborhood of BUB1B	TCP1 MCM2 MCM3	6.71e-04	49	38	3	GNF2_BUB1B
Computational	Neighborhood of HAT1	MCM2 MCM3 USP1	7.12e-04	50	38	3	GNF2_HAT1
Computational	Genes upregulated in subsets of cells of a given type within various tumors	MCM2 MCM3 USP1	7.12e-04	50	38	3	GAVISH_3CA_MALIGNANT_METAPROGRAM_2_CELL_CYCLE_G1_S
Computational	Neighborhood of DNMT1	TCP1 MCM2 MCM3 USP1	7.64e-04	118	38	4	MORF_DNMT1
Computational	Neighborhood of MCM4	TCP1 MCM2 MCM3	8.45e-04	53	38	3	GNF2_MCM4
Computational	Neighborhood of RAD23A	HYOU1 TCP1 EIF4A1 DIAPH1 MCM2 MCM3	1.27e-03	348	38	6	MORF_RAD23A
Computational	Neighborhood of MCM5	MCM2 MCM3 USP1	1.27e-03	61	38	3	GNF2_MCM5
Computational	Neighborhood of XRCC5	SRSF2 TCP1 DIAPH1 MCM2 USP1	1.33e-03	235	38	5	MORF_XRCC5
Disease	Progressive supranuclear palsy	SRSF2 MAPT	8.27e-05	6	70	2	C0038868
Disease	Ophthalmoplegia, Progressive Supranuclear	SRSF2 MAPT	8.27e-05	6	70	2	C4551862
Disease	Supranuclear Palsy, Progressive, 1	SRSF2 MAPT	8.27e-05	6	70	2	C4551863
Disease	primary biliary cirrhosis	ARID3A MAPT CAPSL WDFY4	2.87e-04	133	70	4	EFO_1001486
Disease	venous thromboembolism	RELN TRPM3 STX10 NLRP2 CCDC93 ITPR3	7.85e-04	460	70	6	EFO_0004286
Disease	Precancerous Conditions	TRIO MAGED4 TNK2	2.30e-03	110	70	3	C0032927
Disease	Condition, Preneoplastic	TRIO MAGED4 TNK2	2.30e-03	110	70	3	C0282313

Protein segments in the cluster

Peptide	Gene	Start	Entry
MRQMVQDFDHDKQEA	CEP152	656	O94986
VMVVNGKDDMHDVED	ADD3	626	Q9UEY8
DMDHVMKAKSIREFD	ABHD3	291	Q8WU67
MDDEMKREHLAAEQR	C6orf163	131	Q5TEZ5
DDIRMEMDDFNEVFQ	DIAPH1	381	O60610
SMSEHEANSERFEME	DNAI2	56	Q9GZS0
MDDFIREVNAMHSLD	TNK2	171	Q07912
RMKEHMEDRVNVADF	CFAP206	381	Q8IYR0
RNDFLDDLHMDMLEE	PDZRN3	516	Q9UPQ7
VMDTHGSNEKFLEDM	PADI1	311	Q9ULC6
EMDNHMSDKDESCYD	INTS3	516	Q68E01
LDMMKAARDGVEDHS	ITPR3	1346	Q14573
NEDMHDSESYRRMLE	LRRC9	456	Q6ZRR7
KMNDQDRTSIHEAME	MCM2	591	P49736
FKTMDVDMAEEHARA	MAGED4	616	Q96JG8
HEMEEEASGKAAQMA	JHY	86	Q6NUN7
HTDMEAELEDMRAEA	SLC2A7	246	Q6PXP3
RELMADSENMDVLHE	HERC2	3906	O95714
FMTMNAEDEKRDAEH	KCNK3	246	O14649
MSFGRDMELEHFDER	DCLK1	1	O15075
HSEENSEMFMEGANK	FSIP2	2126	Q5CZC0
DFTVSAMHGDMDQKE	EIF4A1	296	P60842
AESHNRIDLMDMADQ	KLHL8	176	Q9P2G9
ARHAEIMDSFKEKME	PDE9A	426	O76083
FTQSEDSQMKHREEM	LAX1	351	Q8IWV1
DSQMKHREEMSNEDS	LAX1	356	Q8IWV1
KHERAGYLDEDQMEM	EVC2	626	Q86UK5
MESERDRQHFDKEVM	LRRC2	331	Q9BYS8
EMIDEKLMFHVDNGA	LAMA2	2991	P24043
HFGDEDQAMRAFELM	NLRP2	371	Q9NX02
DDVEEFHERAQEAMM	KDM5A	851	P29375
FHERAQEAMMDETPD	KDM5A	856	P29375
SEDRFLHIMEDDSME	KDM5A	1476	P29375
EMDFEMIETNDTMRH	MFSD4B	451	Q5TF39
AFDMFMEDKTSVNEH	RELN	2696	P78509
RLMKEVMEHYADQDD	PLOD2	91	O00469
FDKMSDMDRTAIHEV	MCM3	411	P25205
AMTHDEDLDRRYNME	CCDC93	446	Q567U6
HMAQIEGLMDDVDFK	HYOU1	326	Q9Y4L1
MDDDNNRTLDFKEFM	CAPSL	51	Q8WWF8
VMESEMKFDKDHDGL	GBA2	651	Q9HCG7
NNDIRMEMAFHEASK	CFAP70	751	Q5T0N1
ASDVFEMMKDLRHEN	GUCY2F	591	P51841
EEDMIDTFQFPDMDH	CCDC183	491	Q5T5S1
EADRNSMHVDMADEA	MCCC1	81	Q96RQ3
DTLFIMEMKHEFEEA	MAN1A1	246	P33908
MSDKTDHEARKMYDD	MAN1A2	411	O60476
HDGMLDRDEFAVAMF	EPS15	176	P42566
LDEMNAQHFLDMADK	FAM83H	181	Q6ZRV2
RNAMAHRDSEMKEEC	MCOLN2	26	Q8IZK6
RFHDKRDAEDAMDAM	SRSF2	61	Q01130
DFLHENSMLREEIAM	POTEJ	606	P0CG39
FMQSILHTMEREADD	SETX	266	Q7Z333
NDFMCDEMERSLHDA	TCP1	381	P17987
HFGDEDQAMRAFELM	NLRP7	336	Q8WX94
VDVVHMDENSLEFDM	POLR1C	51	O15160
NREHMEDDDEEMQQK	SLC28A3	66	Q9HAS3
EEHFEDMASDEDMKP	ARID3A	111	Q99856
HFKDEEMTREGDEME	TCEAL7	56	Q9BRU2
HDMNFSNEDMIREFD	TCEAL4	146	Q96EI5
MSQDDHGLEQEMERE	ZFHX4	1431	Q86UP3
DAFAQEMDHTQSRMD	STX10	196	O60499
MAHEASENDMVDDIS	TRPM3	701	Q9HCF6
DLEERMDEGDAAIMH	WDFY4	816	Q6ZS81
AIHDMNFSNEDMIRE	TCEAL2	156	Q9H3H9
MAEPRQEFEVMEDHA	MAPT	1	P10636
AFLDAKERSDHKEMM	TBXT	216	O15178
KLRMYQMEAEDTDSH	SMCO2	231	A6NFE2
RDMFVEMLDDFRDNH	ZBTB1	501	Q9Y2K1
MFKSAIMEENERDHR	ZBTB1	561	Q9Y2K1
FDNDDLMAKMAEHPE	SLC30A5	166	Q8TAD4
EDMFKDNFDEMDRSR	TUBG2	411	Q9NRH3
ETDFMAFHQEHEVRM	SUN1	421	O94901
INSIEMDSMRHSEDF	USP1	246	O94782
DMDMIRDCAEKVASH	TRIO	981	O75962