Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionG protein-coupled receptor activity

OR5D16 ADORA2B TPRA1 OR9G1 OR8B4 CALCR OR10A4 OR2M5 OR10C1 OR2M3 OR9G9

7.48e-068844911GO:0004930
GeneOntologyMolecularFunctionolfactory receptor activity

OR5D16 OR9G1 OR8B4 OR10A4 OR2M5 OR10C1 OR2M3 OR9G9

9.17e-06431498GO:0004984
GeneOntologyMolecularFunctiontransmembrane signaling receptor activity

OR5D16 ADORA2B TPRA1 OR9G1 OR8B4 CALCR OR10A4 OR2M5 OR10C1 OR2M3 IL17RD OR9G9 EPHA4

1.58e-0513534913GO:0004888
GeneOntologyMolecularFunctionL-ornithine transmembrane transporter activity

SLC7A2 SLC7A3

5.87e-055492GO:0000064
GeneOntologyMolecularFunctionL-lysine transmembrane transporter activity

SLC7A2 SLC7A3

2.10e-049492GO:0015189
GeneOntologyMolecularFunctionL-arginine transmembrane transporter activity

SLC7A2 SLC7A3

4.52e-0413492GO:0061459
GeneOntologyMolecularFunctionL-amino acid transmembrane transporter activity

SLC7A2 SLC7A3 SLC38A11

7.06e-0471493GO:0015179
GeneOntologyMolecularFunctionbasic amino acid transmembrane transporter activity

SLC7A2 SLC7A3

1.09e-0320492GO:0015174
GeneOntologyMolecularFunctionoutward rectifier potassium channel activity

PKD2 KCNK13

1.99e-0327492GO:0015271
GeneOntologyMolecularFunctionamino acid transmembrane transporter activity

SLC7A2 SLC7A3 SLC38A11

2.18e-03105493GO:0015171
GeneOntologyBiologicalProcessdetection of chemical stimulus involved in sensory perception of smell

OR5D16 OR9G1 OR8B4 OR10A4 OR2M5 OR10C1 OR2M3 OR9G9

5.33e-06432478GO:0050911
GeneOntologyBiologicalProcesssensory perception of smell

OR5D16 OR9G1 OR8B4 OR10A4 OR2M5 OR10C1 OR2M3 OR9G9

9.13e-06465478GO:0007608
GeneOntologyBiologicalProcessdetection of chemical stimulus involved in sensory perception

OR5D16 OR9G1 OR8B4 OR10A4 OR2M5 OR10C1 OR2M3 OR9G9

1.24e-05485478GO:0050907
GeneOntologyBiologicalProcessdetection of chemical stimulus

OR5D16 OR9G1 OR8B4 OR10A4 OR2M5 OR10C1 OR2M3 OR9G9

2.16e-05524478GO:0009593
GeneOntologyBiologicalProcesssensory perception of chemical stimulus

OR5D16 OR9G1 OR8B4 OR10A4 OR2M5 OR10C1 OR2M3 OR9G9

2.94e-05547478GO:0007606
GeneOntologyBiologicalProcessdetection of stimulus

OR5D16 OR9G1 OR8B4 OR10A4 PKD2 OR2M5 OR10C1 OR2M3 OR9G9

3.10e-05722479GO:0051606
GeneOntologyBiologicalProcessdetection of stimulus involved in sensory perception

OR5D16 OR9G1 OR8B4 OR10A4 OR2M5 OR10C1 OR2M3 OR9G9

4.56e-05582478GO:0050906
GeneOntologyBiologicalProcessG protein-coupled receptor signaling pathway

OR5D16 ADORA2B TPRA1 OR9G1 OR8B4 CALCR OR10A4 MUC19 OR2M5 OR10C1 OR2M3 OR9G9

4.96e-0513954712GO:0007186
GeneOntologyBiologicalProcessL-ornithine transmembrane transport

SLC7A2 SLC7A3

7.58e-056472GO:1903352
GeneOntologyBiologicalProcessornithine transport

SLC7A2 SLC7A3

1.06e-047472GO:0015822
GeneOntologyBiologicalProcessL-arginine import across plasma membrane

SLC7A2 SLC7A3

1.41e-048472GO:0097638
GeneOntologyBiologicalProcessL-lysine transmembrane transport

SLC7A2 SLC7A3

2.26e-0410472GO:1903401
GeneOntologyBiologicalProcessL-lysine transport

SLC7A2 SLC7A3

2.26e-0410472GO:1902022
GeneOntologyBiologicalProcessL-arginine transmembrane transport

SLC7A2 SLC7A3

5.24e-0415472GO:1903826
HumanPhenoElevated gamma-glutamyltransferase level

PKD2 PEX2 XK

3.99e-054783HP:0030948
HumanPhenoAbnormal gamma-glutamyltransferase level

PKD2 PEX2 XK

4.26e-054883HP:0034444
DomainOlfact_rcpt

OR5D16 OR9G1 OR8B4 OR10A4 OR2M5 OR10C1 OR2M3 OR9G9

7.59e-06393498IPR000725
DomainCat_AA_permease

SLC7A2 SLC7A3

2.02e-053492IPR004755
DomainGPCR_Rhodpsn_7TM

OR5D16 ADORA2B OR9G1 OR8B4 OR10A4 OR2M5 OR10C1 OR2M3 OR9G9

5.29e-05670499IPR017452
Domain7tm_1

OR5D16 ADORA2B OR9G1 OR8B4 OR10A4 OR2M5 OR10C1 OR2M3 OR9G9

5.74e-05677499PF00001
DomainG_PROTEIN_RECEP_F1_1

OR5D16 ADORA2B OR9G1 OR8B4 OR10A4 OR2M5 OR10C1 OR2M3 OR9G9

6.28e-05685499PS00237
DomainCAT3

SLC7A2 SLC7A3

6.71e-055492IPR015606
DomainAA_permease_C

SLC7A2 SLC7A3

6.71e-055492PF13906
DomainCAT_C

SLC7A2 SLC7A3

6.71e-055492IPR029485
DomainG_PROTEIN_RECEP_F1_2

OR5D16 ADORA2B OR9G1 OR8B4 OR10A4 OR2M5 OR10C1 OR2M3 OR9G9

6.72e-05691499PS50262
DomainGPCR_Rhodpsn

OR5D16 ADORA2B OR9G1 OR8B4 OR10A4 OR2M5 OR10C1 OR2M3 OR9G9

6.79e-05692499IPR000276
DomainAA/rel_permease1

SLC7A2 SLC7A3

5.16e-0413492IPR002293
DomainAA_permease_2

SLC7A2 SLC7A3

5.16e-0413492PF13520
DomainAA-permease/SLC12A_dom

SLC7A2 SLC7A3

1.51e-0322492IPR004841
DomainAA_permease

SLC7A2 SLC7A3

1.51e-0322492PF00324
PathwayREACTOME_OLFACTORY_SIGNALING_PATHWAY

OR5D16 OR9G1 OR8B4 OR10A4 OR2M5 OR10C1 OR2M3 OR9G9

5.06e-06417348M4072
PathwayKEGG_OLFACTORY_TRANSDUCTION

OR5D16 OR9G1 OR8B4 OR10A4 OR2M5 OR10C1 OR2M3

3.26e-05389347M14091
PathwayREACTOME_SENSORY_PERCEPTION

OR5D16 OR9G1 OR8B4 OR10A4 OR2M5 OR10C1 OR2M3 OR9G9

1.05e-04636348M41834
Pubmed

Different evolutionary processes shaped the mouse and human olfactory receptor gene families.

OR5D16 OR9G1 OR8B4 OR10A4 OR2M5 OR10C1 OR2M3

5.59e-0734050711875048
Pubmed

The olfactory receptor gene superfamily of the mouse.

OR5D16 OR9G1 OR8B4 OR10A4 OR2M5 OR10C1 OR2M3

5.59e-0734050711802173
Pubmed

A unified nomenclature for vertebrate olfactory receptors.

OR5D16 OR9G1 OR8B4 OR10A4 OR2M5 OR10C1 OR2M3

5.92e-0734350732295537
Pubmed

Odorant receptor expressed sequence tags demonstrate olfactory expression of over 400 genes, extensive alternate splicing and unequal expression levels.

OR5D16 OR9G1 OR8B4 OR10A4 OR2M5 OR10C1 OR2M3

6.28e-0734650714611657
Pubmed

A new member of the cationic amino acid transporter family is preferentially expressed in adult mouse brain.

SLC7A2 SLC7A3

6.07e-0635029334265
Pubmed

Differential topochemistry of three cationic amino acid transporter proteins, hCAT1, hCAT2 and hCAT3, in the adult human brain.

SLC7A2 SLC7A3

6.07e-06350222870827
Pubmed

The human olfactory receptor gene family.

OR5D16 OR9G1 OR8B4 OR10A4 OR2M5 OR10C1 OR2M3

1.19e-0554150714983052
Pubmed

High-throughput microarray detection of olfactory receptor gene expression in the mouse.

OR2M5 OR2M3

1.21e-05450215377787
Pubmed

DEFOG: a practical scheme for deciphering families of genes.

OR5D16 OR8B4 OR10A4 OR10C1 OR2M3

1.59e-0521950512213199
Pubmed

IL-17A expression by both T cells and non-T cells contribute to HSV-IL-2-induced CNS demyelination.

RAG2 IL17RD

5.64e-05850236817487
Pubmed

Heterotypic interactions among NACHT domains: implications for regulation of innate immune responses.

XK NLRP4

7.25e-05950215107016
Pubmed

Defining brain wiring patterns and mechanisms through gene trapping in mice.

IL17RD EPHA4

1.82e-041450211242070
Pubmed

Genome-wide SNP associations with rubella-specific cytokine responses in measles-mumps-rubella vaccine recipients.

CNTNAP4 EPHA4

1.82e-041450224811271
Pubmed

Chromosomal location-dependent nonstochastic onset of odor receptor expression.

OR8B4 OR10A4

2.72e-041750220668191
Pubmed

TRIM protein-mediated regulation of inflammatory and innate immune signaling and its association with antiretroviral activity.

TRIM15 TRIM22

3.05e-041850223077300
Pubmed

Dependency of NELF-E-SLUG-KAT2B epigenetic axis in breast cancer carcinogenesis.

NCBP2 PCIF1 CNTNAP4

6.32e-0411650337117180
Pubmed

Amino acid transport across mammalian intestinal and renal epithelia.

SLC7A2 SLC7A3

9.17e-043150218195088
Pubmed

A probabilistic classifier for olfactory receptor pseudogenes.

OR8B4 OR10C1

1.17e-033550216939646
Pubmed

Personal receptor repertoires: olfaction as a model.

OR8B4 OR10C1

1.38e-033850222908908
Cytoband11q11

OR5D16 OR9G9

1.22e-034750211q11
GeneFamilyOlfactory receptors, family 9

OR9G1 OR9G9

1.11e-0323392156
ToppCellprimary_auditory_cortex_(A1C)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_D_(IT_RORB_THEMIS_LINC00507)_5-Exc_L5-6_RORB_LINC00320|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

CNTNAP4 SLC38A11 TRIM22 DNAH14

3.91e-051734944ec147479b359cce1975d57a50ee1437a0e1e663
ToppCellprimary_auditory_cortex_(A1C)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_D_(IT_RORB_THEMIS_LINC00507)_2|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

FIBIN SLC38A11 DNAH14 EPHA4

3.91e-051734948335b77f730ed43fc348a005566e73a103c6774b
ToppCellfacs-Heart-RV-18m-Mesenchymal-smooth_muscle_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TMEM198 XK RASL12 SLC38A11

4.09e-05175494d8e385320f554d974538b7cdc4f8e4767f1455f2
ToppCellE16.5-Mesenchymal-Mesenchymal_structural-Fibroblastic-Chondrocyte|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

ADORA2B SLC7A2 ZC3H11A FIBIN

4.09e-051754948b498eea1ec1c1f27b171025c3d08adf3687bafc
ToppCellE16.5-Mesenchymal-Mesenchymal_structural-Fibroblastic-Chondrocyte-Chondrocyte_mature|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

ADORA2B SLC7A2 ZC3H11A FIBIN

4.09e-05175494a5db428b078938627e61b7e944c1e0c1d61ac2da
ToppCellfacs-Heart-RV-18m-Mesenchymal-smooth_muscle_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TMEM198 XK RASL12 SLC38A11

4.09e-05175494cf15465855602ba135752c18755e3e058dbd42ec
ToppCellAnterior_Cingulate_gyrus_(CgG)-Neuronal-Inh_GABAergic-i_Gaba_2-GABA_VIP_1-Inh_L1_SST_CXCL14|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

SLC7A2 SLC7A3 CALCR CNTNAP4

4.46e-05179494c7afbd10072d36a35cd20ae73670d76b9cefd22d
ToppCellprimary_auditory_cortex_(A1C)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_D_(IT_RORB_THEMIS_LINC00507)_5|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

CNTNAP4 SLC38A11 TRIM22 EPHA4

4.66e-051814946e8c5460021d3999daec58e3d6661a6fa998fd16
ToppCellSubstantia_nigra-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)|Substantia_nigra / BrainAtlas - Mouse McCarroll V32

SLC7A3 TMEM179 CNTNAP4 DISP2

5.40e-05188494b73e8a40393c3f656e2fcfe395a761b1f985c254
ToppCell15-Trachea-Epithelial-Neuroendocrine|Trachea / Age, Tissue, Lineage and Cell class

TMEM179 DISP2 KCNK13 SLC38A11

5.74e-0519149476311fa5f3ae9bb27cf04387a8c92300f2888c28
Diseasememory performance

PCIF1 XK RASL12 CFAP46 EPHA4

5.24e-04409485EFO_0004874
Diseasepseudotumor cerebri

OR9G1 OR9G9

8.21e-0426482EFO_1001132

Protein segments in the cluster

PeptideGeneStartEntry
FTDLCVYFFTFIFCH

CAMLG

271

P49069
FCTDFYGCLFLACFV

ADORA2B

71

P29275
HFQGFFVATIYCFCN

CALCR

381

P30988
AEGYEDCCLAAYAFF

CFAP46

1316

Q8IYW2
GFFCDCTFSAYTGPF

CNTNAP4

981

Q9C0A0
AATCFYAFVGFDCIA

SLC7A2

261

P52569
GFASFFFQSLCCFFG

DISP2

1101

A7MBM2
CVFLVDFEFGCATSY

RAG2

181

P55895
FGCLFFEVSACLDFE

RASL12

156

Q9NYN1
CLCQFFFSAGLAYSE

OR9G1

96

Q8NH87
FSGCLVQFFFFCTFV

OR5D16

96

Q8NGK9
FFLFNLSFIDLCYSC

OR8B4

61

Q96RC9
FFFCFFVNSECYVLV

OR8B4

101

Q96RC9
GFWIFSQYCFLDFCN

LY6G5C

126

Q5SRR4
CFAYFLQDFCGCEVA

IL17RD

376

Q8NFM7
CGFCFVEYYSRADAE

NCBP2

81

P52298
CFFICFFLSEVSGFE

ITIH2

6

P19823
YFALFSCLFGICDAV

EPHA4

6

P54764
FSYCGSREIAHFFCD

OR2M3

166

Q8NG83
FSYCGSREIAHFFCD

OR2M5

166

A3KFT3
FFFESSCPYTFCRHC

MUC19

496

Q7Z5P9
FCAKSSFLFDVYFTC

PEX2

266

P28328
DSLYFCFVAFSTIGF

KCNK13

226

Q9HB14
GFNESDRLVYFCCFF

NLRP4

301

Q96MN2
CLCQFFFSAGLAYSE

OR9G9

96

P0C7N8
QMYFFFFFGAAECCL

OR10A4

101

Q9H209
FFSLAFCDFCLKFLF

ARAF

106

P10398
GVSFECFASPLNCYF

PCIF1

506

Q9H4Z3
FFKAFYECLAACEGS

CRTAP

236

O75718
CSIFGYFVDIEQCEF

DNAH14

1831

Q0VDD8
CFLQEGFYSCEAFLY

CENPI

426

Q92674
FFCMSFFCHLCQGYF

FIBIN

6

Q8TAL6
CIFFATCGYLTFTGF

SLC38A11

211

Q08AI6
GAATCFYAFVGFDCI

SLC7A3

256

Q8WY07
FFFLFFGATECCLLA

OR10C1

101

Q96KK4
TFLFCPTEYCGTFCY

OGA

211

O60502
CEGLYFFEFVSCSAF

CMTM4

81

Q8IZR5
GLCCVDATTFLYFSF

TPRA1

256

Q86W33
YSFFLGCFGVDRFCL

TM2D2

156

Q9BX73
FICEECGKSFSYFSY

ZNF19

161

P17023
CACYFLAFLFSFVVV

TMEM179

11

Q6ZVK1
EDCYFFFYSTCTKGD

ZC3H11A

6

O75152
YFFCENDAEFLCVFC

TRIM15

91

Q9C019
ECNECGKFFTYYSSF

ZNF211

286

Q13398
FFLAACEIIFCFFIF

PKD2

471

Q13563
EDCYFFFYSTCTKGD

ZC3H11B

6

A0A1B0GTU1
PCDFSAFGVFGCQYF

TRIM22

336

Q8IYM9
TCCFTCFDQGFLYAG

WDR87

206

Q6ZQQ6
FRCFEVFCIYFQSGN

XK

81

P51811
CLFGVVYCFFGYRCF

TMEM198

46

Q66K66
YDECGDAFSCYSFFT

ZNF527

276

Q8NB42